Digital Commons Network^™

Quantification Of Antiviral Drug Tenofovir (Tfv) By Surface-Enhanced Raman Spectroscopy (Sers) Using Cumulative Distribution Functions (Cdfs), Marguerite R. Butler, Jana Hrncirova, Meredith Clark, Sucharita Dutta, John B. Cooper

Chemistry & Biochemistry Faculty Publications

Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive spectroscopic technique that generates signal-enhanced fingerprint vibrational spectra of small molecules. However, without rigorous control of SERS substrate active sites, geometry, surface area, or surface functionality, SERS is notoriously irreproducible, complicating the consistent quantitative analysis of small molecules. While evaporatively prepared samples yield significant SERS enhancement resulting in lower detection limits, the distribution of these enhancements along the SERS surface is inherently stochastic. Acquiring spatially resolved SERS spectra of these dried surfaces, we have shown that this enhancement is governed by a power law as a function of analyte concentration. Consequently, by definition, …

Exploration Of Potential Broad-Spectrum Antiviral Targets In The Enterovirus Replication Element: Identification Of Six Distinct 5' Cloverleaves, Morgan G. Daniels, Meagan E. Werner, Rockwell T. Li, Steven M. Pascal

Chemistry & Biochemistry Faculty Publications

Enterovirus genomic replication initiates at a predicted RNA cloverleaf (5′CL) at the 5′ end of the RNA genome. The 5′CL contains one stem (SA) and three stem-loops (SLB, SLC, SLD). Here, we present an analysis of 5′CL conservation and divergence for 209 human health-related serotypes from the enterovirus genus, including enterovirus and rhinovirus species. Phylogenetic analysis indicates six distinct 5′CL serotypes that only partially correlate with the species definition. Additional findings include that 5′CL sequence conservation is higher between the EV species than between the RV species, the 5′CL of EVA and EVB are nearly identical, and RVC has the …

Exploring Interdisciplinary Literacy Practices Supporting Youth Creativity, Critical Literacy, And Climate Change From An Interdisciplinary Perspective, Thomas W. Bean

Teaching & Learning Faculty Publications

Norfolk, Virginia endures frequent tide- and rain-impacted flooding with king tides and flooding neighborhoods. The heavy rainfall envelops parking lots at the naval airbase, and plans are underway to create barrier sea walls that can be adjusted based on conditions. Given various dire predications for future sea level rise, Old Dominion University has created a “Maritime Consortium” aimed at bringing together interested faculty and students from a range of fields (e.g., oceanography, engineering, education, and other fields). At this stage the focus is on compiling a directory of interested parties. So far regular meetings have been held to learn about …

Differences In Urine Creatinine And Osmolality Between Black And White Americans After Accounting For Age, Moisture Intake, Urine Volume, And Socioeconomic Status, Patrick B. Wilson, Ian P. Winter, Josie Burdin

Exercise Science Faculty Publications

Urine osmolality is used throughout research to determine hydration levels. Prior studies have found black individuals to have elevated urine creatinine and osmolality, but it remains unclear which factors explain these findings. This cross-sectional, observational study sought to understand the relationship of self-reported race to urine creatinine and urine osmolality after accounting for age, socioeconomic status, and fluid intake. Data from 1,386 participants of the 2009–2012 National Health and Nutrition Examination Survey were utilized. Age, poverty-to-income ratio (PIR), urine flow rate (UFR), fluid intake, estimated lean body mass (LBM), urine creatinine, and urine osmolality were measured. In a sex-specific manner, …

Advanced Air Mobility, Economic Impacts, And Equity Considerations, Robert M. Mcnab

Economics Faculty Publications

Advanced Air Mobility (AAM) may, in the coming decades, result in tens of thousands of new jobs and billions of dollars in additional economic activity. While much of the discussion surrounding AAM focuses on the technical aspects of the nascent industry, estimates of the potential economic impact vary significantly. Much less attention has been paid in the literature to potential externalities, positive and negative, and how these externalities may impact estimates of economic impact. We argue that much work remains to be done before policy advisors and decisions makers can formulate and implement strategies based on the projections of future …

Removing Development Incentives In Risky Areas Promotes Climate Adaptation, Hannah Druckenmiller, Yanjun (Penny) Liao, Sophie Pesek, Margaret Walls, Shan Zhang

Economics Faculty Publications

As natural disasters grow in frequency and intensity with climate change, limiting the populations and properties in harm’s way will be key to adaptation. This study evaluates one approach to discouraging development in risky areas—eliminating public incentives for development, such as infrastructure investments, disaster assistance and federal flood insurance. Using machine learning and matching techniques, we examine the Coastal Barrier Resources System (CBRS), a set of lands where these federal incentives have been removed. We find that the policy leads to lower development densities inside designated areas, increases development in neighbouring areas, reduces flood damages and alters local demographics. Our …

Energy Efficiency In Additive Manufacturing: Condensed Review, Ismail Fidan, Vivekanand Naikwadi, Suhas Alkunte, Roshan Mishra, Khalid Tantawi

Engineering Technology Faculty Publications

Today, it is significant that the use of additive manufacturing (AM) has growing in almost every aspect of the daily life. A high number of sectors are adapting and implementing this revolutionary production technology in their domain to increase production volumes, reduce the cost of production, fabricate light weight and complex parts in a short period of time, and respond to the manufacturing needs of customers. It is clear that the AM technologies consume energy to complete the production tasks of each part. Therefore, it is imperative to know the impact of energy efficiency in order to economically and properly …

Ground Tire Rubber As A Sustainable Additive: Transforming Desert Sand Behavior, Nabil Ismael, Dalya Ismael, Asmaa Al-Ahmad

Engineering Technology Faculty Publications

Managing waste tires presents a significant challenge globally, particularly in regions experiencing high temperatures and shortage of landfill sites. This issue is affecting countries like Kuwait, where the abundance of waste tires is a major source of environmental and safety risks, particularly during the intensely hot summer months. This extreme heat has sparked numerous fires, leading to substantial air pollution due to thick black smoke. Given the limited disposal options, recycling waste tires and finding practical applications for ground tire rubber (GTR) is essential. To address the challenge, a comprehensive laboratory testing program was conducted, using locally produced rubber aggregates …

Digitalization Of Railway Transportation Through Ai-Powered Services: Digital Twin Trains, Salih Sarp, Murat Kuzlu, Vukica Jovanovic, Zekeriya Polat, Ozgur Guler

Engineering Technology Faculty Publications

Digitalization is a key concept that transformed the various industries through technologies like Internet of Things (IoT), Artificial Intelligence (AI), and Digital Twin (DT). Although innovations provided by the advancement of digitalization have paved the way for more efficient operations and products for transportation, the rail transportation sector struggles to keep up with the rest of the transportation industry, since trains are designed to last for decades, and the insufficient infrastructure investment leads to multiple railroad derailments across the globe. Therefore, the primary aim is to transform current railway systems into human-centric, adaptable, sustainable and future-proof networks, aligning with Industry …

A Benchmark Framework For Data Visualization And Explainable Ai (Xai), Murat Kuzlu, Gokcen Ozdemir, Umut Ozdemir

Engineering Technology Faculty Publications

This research introduces a benchmark framework, called EDUMX, designed for machine learning (ML)-based forecasting and XAI tasks, leveraging the Streamlit open-source Python library. The framework offers a comprehensive suite of functionalities, including data loading, feature selection, relationship analysis, data preprocessing, model selection, metric evaluation, training, and real-time monitoring. Users can easily upload data in diverse formats, explore relationships between variables, preprocess data using various techniques, and assess the performance of the ML model using customizable metrics. With its user-friendly interface, this framework offers invaluable insights for forecasting tasks in various domains, catering to the evolving needs of predictive analytics. EDUMX …

Dynamics Of Cell Membrane Lesions And Adaptive Conductance Under The Electrical Stress, Mantas Silkunas, Olga N. Pakhomova, Giedre Silkuniene, Andrei G. Pakhomov

Bioelectrics Publications

Exceeding physiological limits of the cell membrane potential compromises structural integrity, enabling the passage of normally impermeant solutes and disrupting cell function. Electropermeabilization has been studied extensively at the cellular scale, but not at the individual membrane lesion level. We employed fast total internal reflection fluorescence (TIRF) imaging of Ca(2+) entry transients to discern individual lesions in a hyperpolarized cell membrane and characterize their focality, thresholds, electrical conductance, and the lifecycle. A diffuse and momentary membrane permeabilization without a distinct pore formation was observed already at a -100 mV threshold. Polarizing down to -200 mV created focal pores with a …

Photoluminescence Switching In Quantum Dots Connected With Fluorinated And Hydrogenated Photochromic Molecules, Ephraiem S. Sarabamoun, Jonathan M. Bietsch, Pramod Aryal, Amelia G. Reid, Maurice Curran, Grayson Johnson, Esther H. R. Tsai, Charles W. Machan, Guijun Wang, Joshua J. Choi

Chemistry & Biochemistry Faculty Publications

We investigate switching of photoluminescence (PL) from PbS quantum dots (QDs) crosslinked with two different types of photochromic diarylethene molecules, 4,4'-(1-cyclopentene-1,2-diyl)bis[5-methyl-2-thiophenecarboxylic acid] (1H) and 4,4'-(1-perfluorocyclopentene-1,2-diyl)bis[5-methyl-2-thiophenecarboxylic acid] (2F). Our results show that the QDs crosslinked with the hydrogenated molecule (1H) exhibit a greater amount of switching in photoluminescence intensity compared to QDs crosslinked with the fluorinated molecule (2F). With a combination of differential pulse voltammetry and density functional theory, we attribute the different amount of PL switching to the different energy levels between 1H and 2F molecules which result in different potential barrier …

Synthesis Of Bis-Thioacid Derivatives Of Diarylethene And Their Photochromic Properties, Pramod Aryal, Jonathan Bietsch, Gowri Sankar Grandhi, Richard Chen, Surya B. Adhikari, Ephraiem S. Sarabamoun, Joshua J. Choi, Guijun Wang

Chemistry & Biochemistry Faculty Publications

Diarylethenes (DAEs) are an important class of photoswitchable compounds that typically undergo reversible photochemical conversions between the open and closed cyclized forms upon treatment with UV light or visible light. In this study, we introduced thioacid functional groups to several photochromic dithienylethene (DTE) derivatives and established a method that can be used to prepare these photoswitchable thioacids. Four thioacid-functionalized diarylethene derivatives were synthesized through the activation of carboxylic acids with N-hydroxysuccinimide, followed by reactions with sodium hydrosulfide with yields over 90%. These derivatives exhibited reversible photoswitching and photochromic properties upon treatment with ultraviolet (UV) and visible lights. The thioacid groups …

Parametric Study Of The Effect Of Increased Magnetic Field Exposure On Microalgae Chlorella Vulgaris Growth And Bioactive Compound Production, Sharanabasaweshwara Asundi, Sanurag Rout, Simone Stephen, Sanghamitra Khandual, Sandipan Dutta, Sandeep Kumar

Mechanical & Aerospace Engineering Faculty Publications

This parametric study aimed to analyze the effects of increased magnetic field exposure (MFE) on the growth and production of the bioactive compounds of Chlorella (C.) vulgaris. With the intent of studying the effect of an increased MFE, the magnetic field typically experienced by life on Earth was amplified by an order of magnitude. In the increased-MFE environment, six treatments of C. vulgaris with two repetitions for each treatment were exposed to a magnetic field of 5 Gauss (500 µT) about each axis, which was generated in a state-of-the-art Helmholtz cage. The treatments and the control were characterized by the …

The Feasibility Of Motion Tracking Camera System For Magnetic Suspension Wind Tunnel Tests, Hisham M. Shehata, David Cox, Mark Schoenenberger, Colin Britcher, Eli Shellabarger, Timothy Schott, Brendan Mcgovern

Mechanical & Aerospace Engineering Faculty Publications

The Entry Systems Modeling (ESM) Program at NASA has actively participated in the re-development of the Magnetic Suspension Balance System (MSBS) at the six-inch subsonic wind tunnel at NASA Langley Research Center. This initiative aims to enhance the MSBS system's capabilities, enabling the testing of stingless entry vehicle models at supersonic speeds. To achieve this, control algorithms are required to ensure magnetic levitation control and stability for models during free-oscillation dynamic responses. Currently, the system relies on electromagnetic position sensors to provide real-time 3 degrees of freedom control of a rigid body. While this approach has proven successful for subsonic …

Hardness Removal By A Continuous Flow Electrochemical Reactor From Different Types Of Water, Shahad Fadhil Alrubaye, Naseer A. Al Haboubi, Hussein A. Al-Amili, Aiman H. Al-Allaq, Dhuha Ahmed Mohammed

Mechanical & Aerospace Engineering Faculty Publications

The present study focuses on the technique of hardness removal by using a novel reactor performing an electrocoagulation (EC) process. The variation of alkalinity is also recorded. Continuous flow experiments were conducted for Total Hardness (TH) removal using a transparent plastic reactor using aluminum plate electrodes that have holes so that the water flows through the plates in a zigzag way. The influence of various operating parameters such as the number of plates (two and four), flow rate (600, 1000 L/h), and water type (Tigris River & rejected water from Reverse Osmosis system RO) was investigated. The results showed that …

Parametric Optimization Of Friction Stir Welding Of Aa6061-T6 Samples Using The Copper Donor Stir-Assisted Material Method, Aiman H. Al-Allaq, Joseph Maniscalco, Srinivasa Naik Bhukya, Zhenhua Wu, Abdelmageed Elmustafa

Mechanical & Aerospace Engineering Faculty Publications

This study presents an optimization of the process parameters for the effect of copper (Cu) donor material percentage on the friction stir welding (FSW) of AA6061-T6 alloy. Extensive factorial experiments were conducted to determine the significance of the rotational speed (ω), the transverse speed (v), the interface coefficient of friction (μ), and the Cu donor material percentage in the plunge, left, right, and downstream zones. Design Expert 13 software was used to identify the number of simulation experiments to be conducted using the Abaqus simulation software. From Design Expert 13, which is a thorough multi-objective optimization analysis software, we were …

Development Of A Two-Finger Haptic Robotic Hand With Novel Stiffness Detection And Impedance Control, Vahid Mohammadi, Ramin Shahbad, Mojtaba Hosseini, Mohammad Hossein Gholampour, Saeed Shiry Ghidary, Farshid Najafi, Ahad Behboodi

Mechanical & Aerospace Engineering Faculty Publications

Haptic hands and grippers, designed to enable skillful object manipulation, are pivotal for high-precision interaction with environments. These technologies are particularly vital in fields such as minimally invasive surgery, where they enhance surgical accuracy and tactile feedback: in the development of advanced prosthetic limbs, offering users improved functionality and a more natural sense of touch, and within industrial automation and manufacturing, they contribute to more efficient, safe, and flexible production processes. This paper presents the development of a two-finger robotic hand that employs simple yet precise strategies to manipulate objects without damaging or dropping them. Our innovative approach fused force-sensitive …

Factors Affecting Electrocoagulation Process For Different Water Types: A Review, Shahad Fadhil Abed Al-Rubaye, Naseer A. Alhaboubi, Aiman H. Al-Allaq

Mechanical & Aerospace Engineering Faculty Publications

Raw water must meet specific physical, chemical, and biological requirements to be suitable for drinking. There are various techniques available for treating wastewater, and aside from conventional methods that involve chemicals, electrocoagulation is an efficient and advanced approach. Electrocoagulation has proven effective in treating many pollutants, including bacteria, viruses, iron, fluoride, sulfate, boron, hardness, and turbidity. Total suspended solids, organic and inorganic materials, chemical oxygen demand COD, biochemical oxygen demand BOD, and color. It finds extensive application in treating different types of water and wastewater due to its exceptional ability to remove diverse contaminants. Recently, electrocoagulation has garnered significant attention …

A Comprehensive Review Of Piezoelectric Ultrasonic Motors: Classifications, Characterization, Fabrication, Applications, And Future Challenges, Sidra Naz, Tian-Bing Xu

Mechanical & Aerospace Engineering Faculty Publications

Piezoelectric ultrasonic motors (USMs) are actuators that use ultrasonic frequency piezoelectric vibration-generated waves to transform electrical energy into rotary or translating motion. USMs receive more attention because they offer distinct qualities over traditional magnet-coil-based motors, such as miniaturization, great accuracy, speed, non-magnetic nature, silent operation, straightforward construction, broad temperature operations, and adaptability. This review study focuses on the principle of USMs and their classifications, characterization, fabrication methods, applications, and future challenges. Firstly, the classifications of USMs, especially, standing-wave, traveling-wave, hybrid-mode, and multi-degree-of-freedom USMs, are summarized, and their respective functioning principles are explained. Secondly, finite element modeling analysis for design and …

Forced Displacement Technique For Measuring Blunt Body Aerodynamics In A Magnetic Suspension Wind Tunnel, Mark Schoenenberger, David Cox, Colin Britcher, Caleb Hull

Mechanical & Aerospace Engineering Faculty Publications

The Old Dominion University/NASA Langley 6-Inch Magnetic Suspension Wind Tunnel has developed the ability to levitate blunt bodies which can oscillate freely about the yaw axis. This allows for the measurement of static and dynamic stability coefficients without sting interference. The magnetic suspension controller introduces other translational forces which affect the vehicle dynamics complicating data reduction. Exciting model oscillations in a reliable way has also been a challenge. A new test method has been developed that produces capsule oscillations from forced oscillatory translational motion at the resonant yaw oscillatory frequency of the capsule. After oscillations are excited, the translational forcing …

The Benefits Of Interdisciplinary Learning Opportunities For Undergraduate Mechanical Engineering Students, Isaac Koduah Kumi, Stacie I. Ringleb, Francisco Cima, Orlando M. Ayala, Krishnanand Kaipa, Jennifer Jill Kidd, Kristie Gutierrez, Pilar Pazos, Danielle Marie Rhemer

Mechanical & Aerospace Engineering Faculty Publications

Two project-based learning approaches were implemented in a 100-level information literacy class in the Mechanical Engineering program at a mid-Atlantic university. One approach, the treatment group, partnered engineering students with education students to develop and deliver engineering lessons to elementary school students. In the second approach, the comparison group, engineering students were partnered with their engineering classmates to work on an engineering problem using the engineering design process. The two projects were designed to have similar durations and course point values. For both projects, teams were formed, and peer evaluations were completed using the Comprehensive Assessment of Team Member Effectiveness …

Fabrication Of Smooth Sac305 Thin Film Via Magnetron Sputtering, M. Ojha, A. A. Elmustafa

Mechanical & Aerospace Engineering Faculty Publications

SAC305 (96.5 wt% Sn, 3 wt% Ag, 0.5 wt%Cu) solder is increasingly becoming popular due to its reliability good characteristics and performance in addition to the environmental concerns and regulations that restrict the use of lead in nano/microelectronic products. In nano/microelectronics, manufacturing smooth solder coatings free of defects such as voids and cracks, which can compromise joint reliability is crucial. Magnetron sputtering offers a high degree of control over film thickness and composition, resulting in films with excellent uniformity and adhesion. Despite these advantages, fabricating continuous and robust SAC305 films using magnetron sputtering remains a difficult task with limited research …

Reflections Of Undergraduate Engineering Students Completing A Cross Disciplinary Robotics Project With Pre-Service Teachers And Fifth Graders In An Electromechanical Systems Course, Krishnanand Kaipa, Jennifer Kidd, Isaac Koduah Kumi, Stacie I. Ringleb, Orlando M. Ayala, Kristie Gutierrez, Francisco Cima, Danielle Marie Rhemer

Mechanical & Aerospace Engineering Faculty Publications

Engineering is becoming increasingly cross-disciplinary, requiring students to develop skills in multiple engineering disciplines (e.g., mechanical engineering students having to learn the basics of electronics, instrumentation, and coding) and interprofessional skills to integrate perspectives from people outside their field. In the workplace, engineering teams are frequently multidisciplinary, and often, people from outside of engineering are part of the team that brings a product to market. Additionally, teams are often diverse in age, race, gender, and in other areas. Teams that creatively utilize the contrasting perspectives and ideas arising from these differences can positively affect team performance and generate solutions effective …

Weak-Strong Beam-Beam Simulation With Crab Cavity Noises For The Hadron Storage Ring Of The Electron-Ion Collider, Y. Luo, B. Gamage, C. Montag, D. Marx, D. Xu, F. Willeke, H. Huang, H. Lovelace Iii, J. Berg, M. Blaskiewicz, S. Peggs, T. Satogata, V. Ptitsyn, V. Morozov, Y. Hao

Mathematics & Statistics Faculty Publications

The Electron Ion Collider (EIC), to be constructed at Brookhaven National Laboratory, will collide polarized high-energy electron beams with hadron beams, achieving luminosities of up to 1 X 10³⁴cm⁻²s⁻¹ in the center-mass energy range of 20-140 GeV. Crab cavities are employed to compensate for the geometric luminosity loss caused by a large crossing angle of 25 mrad in the interaction region. The phase noise in crab cavities will induce a significant emittance growth for the hadron beams in the Hadron Storage Ring (HSR). Various models have been utilized to study the effects of crab cavity …

A Novel Computational Analysis Of Boundary-Driven Two-Dimensional Heat Flow With Internal Heat Generation, Muhammad Abid, Madiha Bibi, Nasir Yasin, Muhammad Shahid

Mathematics & Statistics Faculty Publications

Accurate numerical solution of parabolic and elliptic partial differential equations governing two-dimensional heat transfer is critical for engineering simulations but computationally challenging. This work employs key numerical techniques finite differences, conjugate gradients, and Crank-Nicolson time stepping to solve the heat diffusion equation and analyze method performance. The Poisson equation is discretized using second-order central finite differences and solved with the conjugate gradient approach to determine the steady state solution. The transient heat equation is integrated in time via the Crank-Nicolson implicit scheme, also utilizing conjugate gradients. The methods effectively compute solutions matching analytical and boundary conditions. Convergence and stability are …

Plasma Protein Signatures Of Adult Asthma, Gordon J. Smilnak, Yura Lee, Abhijnan Chattopadhyay, Annah B. Wyss, Julie D. White, Sinjini Sikdar, Jianping Jin, Andrew J. Grant, Alison A. Motsinger-Reif, Jian-Liang Li, Mikyeong Lee, Bing Yu, Stephanie J. London

Mathematics & Statistics Faculty Publications

Background: Adult asthma is complex and incompletely understood. Plasma proteomics is an evolving technique that can both generate biomarkers and provide insights into disease mechanisms. We aimed to identify plasma proteomic signatures of adult asthma.

Methods: Protein abundance in plasma was measured in individuals from the Agricultural Lung Health Study (ALHS) (761 asthma, 1095 non-case) and the Atherosclerosis Risk in Communities study (470 asthma, 10,669 non-case) using the SOMAScan 5K array. Associations with asthma were estimated using covariate adjusted logistic regression and meta-analyzed using inverse-variance weighting. Additionally, in ALHS, we examined phenotypes based on both asthma and seroatopy (asthma with …

Understanding The Application Of Evolutionary Psychology In Consumer Behavior: A Review And Future Research Agenda, Faegheh Taheran, Veronica L. Thomas, Kendra Fowler, Abdolati Mortazavi

Marketing Faculty Publications

This paper is the first to offer a comprehensive literature review of the role of evolutionary psychology (EP) in marketing and consumer behavior. This study takes a holistic approach, combining techniques of a systematic review with bibliometric analysis, to provide a performance analysis and identify theories and methodologies used in the literature. Most importantly, by studying the current state of EP, we elucidate six major themes: the role of gender in families, the role of affect in consumer behavior, food preferences and shopping behavior, motivations for and consequences of status signaling, the impact of ovulation on consumer motives and behaviors, …

Narrative Transportation: A Systematic Literature Review And Future Research Agenda, Veronica L. Thomas, Jaime L. Grigsby

Marketing Faculty Publications

Consumers are inundated with opportunities to become engaged with marketing-generated stories, from watching an influencer detail her adventures abroad or a commercial about a military service member who makes it home just in time for the holidays. When consumers become so engaged with a story that they begin to connect with the story characters and imagine what will happen next, they experience a process known as narrative transportation, which has significant positive outcomes for marketers. Given the value that narrative transportation provides to marketers, we conduct a systematic literature review to both synthesize and provide direction on the literature of …

International Master's Degree Students' Experiences Of Support At A Finnish University, Anduena Ballo, Sotiria Varis, Charles Mathies, Kalypso Filippou

Educational Leadership & Workforce Development Faculty Publications

This phenomenographic study explores international master’s degree students’ ways of experiencing support in Finnish higher education. The study draws on Schlossberg’s Transition Model and the Culturally Engaging Campus Environments Model as a conceptual framework. The phenomenographic analysis of 17 interviews with international master’s degree students identified four ways of experiencing support as: (a) study system adjustment, (b) learning enhancement, (c) personal growth, and (d) autonomy development. The findings identified participants’ experiencing support in relationships, use of information, communication, services, the flexibility of studies, learning and study environments. The presence of two indicators, Humanizing Educational Environments and Availability of Holistic Support …