Digital Commons Network^™

Impact Of Educational Attainment On Coronary Heart Disease Risk Among Black Individuals, Lyndzee Bensky

Undergraduate Student Symposium

Coronary heart disease disproportionately affects Black individuals and is caused by the buildup of fatty acids in the heart. Research has shown a correlation between educational attainment and the diagnosis of coronary heart disease in Black individuals. Higher levels of education—ranging from high school diplomas to college degrees—may enhance individuals' understanding of health issues and preventive measures related to this disease. This study aims to explore the relationship between educational attainment and coronary heart disease among Black individuals. Using a cross-sectional study design, the researchers will analyze data from the 2023 National Health Interview Survey. The study will create an …

Investigation Children's Sensory Responses To Stressful Stimuli Using Eye Tracking Technology, Pearly Trivedi

Undergraduate Student Symposium

Children diagnosed with Autism Spectrum Disorder (ASD) often have a challenging time navigating stressful situations. This can be connected to the differences in emotional regulation and sensory processing when compared to children who are neurotypical. Despite the research performed on ASD, there seems to be a gap in understanding how effectively children with ASD are able to reconnect with reality after experiencing an overstimulating environment. To bridge the gap, this study was performed to use advanced eye-tracking technology to gather objective data on key indicators such as facial expressions, pupil dilation, and eye movement patterns. By comparing the responses of …

Modeling Nicotine, At-1001, & Varenicline At The α3β4 Nicotine Acetylcholine Receptor, Japji G. Madan, Mourya Khandai, Andersen Cheong

Undergraduate Student Symposium

The escalating prevalence of nicotine addiction among adolescents has been linked to the increasing use of e-cigarettes, known as vapes. Approximately, 1.63 million students in the United States (ages 11-18) use vapes, reflecting a concerning trend of nicotine dependence among adolescents. Activation of the nicotine acetylcholine receptor (nAChR) can modulate the dopamine pathways in the mesolimbic system, increasing nicotine addictive behavior. A 3-D printed molecular model was prepared using the PDB file 6PV7, to explore the molecular dynamics of one of the binding sites between subunits A and B of the pentameric receptor. This model highlights the binding of two …

Playing Stereoscopic Video Games Enhances The Precision But Not The Accuracy Of Depth Perception, Charlene Li, Nada Bleibel, Lara Cereminati, Yingzi Luo, Betty Z. Li Ph.D., Dennis M. Levi Ph.D., Sandy W. Chat

Undergraduate Student Symposium

Purpose. We recently reported that playing immersive video games in a three-dimensions (3D) environment boosts stereo vision in young adults with normal vision. Here we asked whether the improvement in stereoscopic acuity (precision) was the result of a reduced disparity pedestal, as indicated by a decreased subjective depth bias (accuracy).

Methods. Twenty-one university students with normal visual acuity and stereoacuity were recruited. All of them had limited previous video game experience, and none had ever played 3D video games. Participants were required to play stereoscopic 3D video games for a total of 40 hours, 2 hours per session, over 4-5 …

Psychedelic Substituted Phenethylamine Alters Human Neural Progenitor Cell Morphology, Proliferation, And Survival, Omar E. Saleh, Grace K. Wong, Chase A. Gonzales, Mark Apterman, Laury Pierre, Stacey Doret, Isaac Hai, Travis J.A. Craddock

Undergraduate Student Symposium

Examining how psychedelic substituted phenethylamines affect neural plasticity is key to understanding harms and potential medical implications of recreational drugs. The microtubule cytoskeleton has been proposed to modulate the effects of phenethylamines as a downstream effector and through scaffolding mechanisms. Microtubules play a crucial role in neurite outgrowth, protein transport, and synaptic stability in cells. Our group has shown that specific psychedelic substituted phenethylamines (25B-NBF, 25C-NBF, and DMBMPP) alter microtubule formation in a dose-dependent manner. As these phenethylamines limit microtubule capacities, they may impact cytoskeletal-mediated neural plasticity. This study’s purpose is to determine if substituted phenethylamines, 25B-NBF, 25C-NBF, and DMBMPP …

Resilience And Its Effects On Psychological Well Being During The Covid-19 Pandemic, Taylor Reinsel

Undergraduate Student Symposium

Stressors and trauma in life are unavoidable. However, the way we respond and adapt to them can be within our control. This response differs from person to person, but there are factors that can influence the likelihood of an individual rebounding from a crisis, as well as factors that can put them at a higher risk of developing mental illness. One of the main factors that influences Psychological Well Being is the presence of Resilience. The main goal of this study was to examine how factors of Resilience relate to Psychological Well Being and COVID-19 Well Being during the COVID-19 …

Sgi-1027 Small Molecule Inhibits Dnmt And Promotes P21-Mediated Apoptosis Via Epigenetic Alterations In Sk-N-Sh Neuroblastoma Cells, Sadhna Seth, Anika Singh, Shyam Sundar Jaganathan Ph.D.

Undergraduate Student Symposium

Neuroblastoma is an aggressive childhood cancer originating from neural crest cells. Treatment for high-risk neuroblastoma includes chemotherapy. Emerging evidence indicates that DNMT inhibitor codenamed SGI-1027 may facilitate cell cycle arrest and induce apoptosis by modulating cell cycle regulatory pathways. Therefore, we hypothesize that SGI-1027 treatment could lead to apoptosis mediated cell death in SK-N-SH cells through the upregulation of p21 transcription.

This study investigated whether SGI-1027, a DNA methyltransferase inhibitor, causes DNA methylation and upregulation of p21 through a p53-independent pathway, which could lead to cell cycle arrest and intrinsic-pathway mediated apoptosis in SK-N-SH cells. To assess the effects of …

Spliceosomal Modulation Induces Immunogenicity Of Melanoma Cells And In Vivo Immune Response, Sadeeshkumar Velayutham, Shweta Shah, Tulsi Desai, Keiran S.M. Smalley Ph.D., Aveta Singh Ph.D., Jun Yong Choi Ph.D.

Undergraduate Student Symposium

Melanoma is an aggressive skin cancer with high mortality rates, often driven by BRAF and NRAS mutations. While targeted therapies like Vemurafenib have improved outcomes in BRAF-mutant melanoma, resistance and adverse effects limit their long-term efficacy. There is an urgent need for novel therapeutic approaches to overcome these challenges. This study investigates the efficacy of novel anti-melanoma compounds, 2155-14 and 2155-18, targeting spliceosomal proteins, in a xenograft model derived from the A375 BRAF/NRAS double mutant cell line. Seven-week-old mice were implanted with A375 BRAF/NRAS mutant cells and treated with 2155-14 or 2155-18. Treatments were administered subcutaneously thrice weekly. Tumor growth …

Targeting The Renin-Angiotensin System For The Treatment Of Cerebral Amyloid Angiopathy, Ariana Hernandez, Chana Vogel, Victoria Pulido-Correa, Natalia Noto, Yazmin Restrepo, Shay Moen, Julianna Bonetti

Undergraduate Student Symposium

Cerebral amyloid angiopathy (CAA), the accumulation of amyloid proteins in the cerebral vasculature, can increase the risk of stroke, vascular cognitive impairment, and dementia. CAA is highly comorbid with Alzheimer’s disease and contributes to Alzheimer’s pathology by affecting the clearance of amyloid from the brain. Epidemiological studies suggest that certain renin-angiotensin system-targeting drugs, commonly used for the treatment of hypertension, decrease the risk of dementia. This study assesses whether two FDA-approved RAS-targeting drugs: telmisartan [a brain-penetrant angiotensin receptor blocker (ARB)], and lisinopril [a brain-penetrant angiotensin-converting enzyme (ACE) inhibitor]; can be repurposed to mitigate CAA, associated neuropathologies, and cognitive decline in …

Synergistic Anticancer Effects Of Jq-1 And Doxorubicin Via Myc Downregulation And Apoptosis Induction, Abby Morrill, Srika Saai Talanki, Sneha Subhash, Sabrin Safar, Maria Moreno Hollweg, Kyuree Chang, María Guillén-Méndez, Swara Chindahade

Undergraduate Student Symposium

Aggressive cancers are particularly challenging due to their rapid growth, ability to adapt, and resistance to single therapies. Combination therapies or a multipronged approach can increase tumor cell killing and limit the development of drug resistance. The potential of combining conventional chemotherapy with targeted therapies was investigated. To determine the best drug combinations, viability assays using an 8 x 8 dose response matrix format (checkerboard) with small-step serial dilutions of cytotoxic and targeted drugs was performed. The resulting viability data, as determined by MTS assay, was analyzed using the web application SynergyFinder. The results indicated that the combined drug treatment …

Write To Calm: How College Students Use Writing To Manage Stress And Anxiety, Tanvi Rudrangi

Undergraduate Student Symposium

Writing has gained attention for its mental health benefits, particularly among high-stress populations, such as adolescents and young adults. College students, facing academic pressures, social challenges, and transitions to adulthood, are an ideal group for studying the potential therapeutic impact of this practice. This study explores how college students use writing as a tool to manage stress and anxiety. The different forms of writing therapy, a technique involving writing to process emotions and experiences, that are explored in this study include free-form journaling, expressive writing (e.g., letters, personal essays, etc.), creative writing (e.g., poetry, stories, etc.), and structured writing, which …

My Oath Of Healing And Living, Samuel B. John Mph

be Still

No abstract provided.

Nsu Kpcom Link - Spring 2025 - Volume 4.1, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

The Halmos Pulse, Spring 2025, Claudia Diaz, Dahlilah Bernstein

The Halmos Pulse

No abstract provided.

Lessons From The Picu, Lia M. Smerina

be Still

No abstract provided.

Sacred Oath Of Healing - Volume 9

be Still

No abstract provided.

The Healing Power Of A Welcomed Hug, Tara Mckenna

be Still

No abstract provided.

Cultural And Religious Perspectives On Suicide And Healing, Arielle Friedman

be Still

This essay is built off of a paper I wrote in a college global health course on culture and mental illness. I have always been fascinated by cultural interpretations of illness & believe that as a future physician, it is my responsibility to educate myself and others on the complex interplay between religious ideologies & recognition/management of biological disease in order to provide appropriate patient-centered care.

Embracing The Sacred Oath Of Healing: Lessons From When Breath Becomes Air, Rudayna S. Tabbara

be Still

This essay explores how When Breath Becomes Air embodies the Sacred Oath of Healing through Paul Kalanithi’s journey as a physician and a patient.

Helping As A Student, Dayna R. Smerina

be Still

Being a medical student can sometimes feel powerless. However, there are special ways that students can make an impact on their patient's lives.

Nourishing The Body, Nurturing The Soul, Vidhi Raval

be Still

No abstract provided.

Beyond Myself - Healing Through Pain, Marianne Koleng

be Still

In this piece I reflect on the importance of setbacks, non-linear growth, injuries, and pain and their ability to provide self-reflection, a platform for growth, and an crucial reminder of the fragility of life. I have often been self-critical for not following a "traditional" path in life, and reflecting on my experiences allows me to show myself grace and hopefully may influence others to do so as well.

The Sacrifices Of Being Away, Claudia Pedreira

be Still

No abstract provided.

Revealing The Indonesian Crazy Rich Prisoner On Social Media: A Multimodal Discourse Analysis, Krisna Megantari, Heru Nugroho, Dian Arymami

The Qualitative Report

Although flexing is commonly perceived as a negative connotation in society, this phenomenon on digital media industry is fantastically entertaining. This study aims to reveal how the media shapes the phenomenon of Indonesian crazy rich prisoners. Using a multimodal discourse analysis on the YouTube video screenshots were analyzed qualitatively. In dissecting this, three terms are used: representational meaning, interactive meaning, and compositional meaning (Van Leeuwen & Jewitt, 2004). Findings shed some light on three symbolic language themes: hedonism, spectacle society, and homo digitalis. The present study theoretically and practically contributes to the dimensions of the digital media industry, where media …

Understanding Tourist Behavior In Heritage Hotels: A Netnographic Analysis Through The Lens Of The C-A-C Model, Narayan Prabhu, Naresh P. Nayak, Chuyen T. Nguyen, Gunveen Kaur Walia

The Qualitative Report

Tourist behavior in heritage hotels significantly impacts guest experiences and loyalty. This study explores tourist perceptions of Rajasthan's heritage hotels, a prime location due to its numerous converted historical structures. Employing a netnographic approach, the research analyzes online reviews from 2020 to mid-2023 on Google Reviews. Findings reveal a combination of positive and negative comments across cognitive (infrastructure, environment, history, architecture), affective (service experience, ambiance), and conative (revisit intentions, recommendations) factors. While guests expressed strong positive cognitive and affective responses, some management practices received negative feedback. High revisit intentions and recommendations suggest an overall positive experience. The study adds to …

The Current - Volume 35 Issue 11, Nova Southeastern University

Student Newspapers

No abstract provided.

Reliability And Validity In Qualitative Research Revisited And The Role Of Ai, Prokopis A. Christou

The Qualitative Report

The evolving nature of research and the integration of new technologies, such as Artificial Intelligence (AI), introduce new challenges and threats, necessitating a re-examination of the key criteria of reliability and validity. In this paper, I revisit these concepts in the context of qualitative research, highlighting their evolving meanings and significance. I begin by defining reliability and validity and explaining their importance. Following this, I discuss strategies for establishing these criteria within qualitative studies and offer guidelines for maintaining rigor in the current research landscape. While emphasizing the need for human oversight, intervention, and interpretation, I underscore how to ensure …

Group Dynamics Of Solution-Oriented Virtual Teams In Indonesian Startups: A Thematic Analysis, Tri Astuti, Avin Fadilla Helmi, Bagus Riyono

The Qualitative Report

The relationship between employees is currently undergoing quite significant changes. Initially, relationships were formed through direct interaction in traditional teams. However, in recent decades, relationships have not only occurred directly but can also occur because technology and networks, such as virtual teams, mediate them. The change from traditional teams to virtual teams results in changes in relationship dynamics. With this change, the question asked in this study is, how are group dynamics formed in virtual teams? Through this question, the purpose of the study was identified, namely, to develop a theory of virtual team group dynamics in startup companies. The …

Child Marriage Traditions In Pakistan: Reconstructing (In) Security And Subjective Well-Being Of Children, Makhtoom Ahmed, Muhammad Zaman, Hifza Irfan

The Qualitative Report

This article reports on child marriage traditions in the past and in contemporary times vis-a-vis promoting security, insecurity, and well-being in Pakistan. Although the practice of child marriage has begun to decline due to social change, modernisation, and development in urban areas, it tends to linger on in rural communities within Pakistan. In such communities, there is a general perception that early marriage is in the interest and well-being of couples as it allows them to experience long-term marital intimacy and life satisfaction. The present study is part of an extensive ethnographic study in which the authors analysed interview data …

Exploring The Causes Of Plwha Non-Adherence With Antiretroviral Therapy: Implications For Practice In The Post-Covid-19 Era, A Phenomenological Study, Adriani Suwito, Evi Hasnita, Nurhayati -. Nurhayati, Oktavianis -. Oktavianis

The Qualitative Report

One of the goals of HIV/AIDS health services is to combat patients’ non-adherence with medication. This is the key to providing effective care for these patients. If a patient is rebellious or undisciplined in following his treatment regimen, the consequences can include decreased production, increased morbidity, and even death. However, in the post-COVID-19 period, where health protocol adherence remains strong, there are concerns regarding the potential spread of HIV/AIDS. The purpose of this qualitative phenomenon study is to investigate the factors that contribute to non-adherence to medicine in HIV/AIDS patients during the post-COVID-19 condition to remove barriers to patient treatment. …