Digital Commons Network^™

A Genome-To-Genome Analysis Of Associations Between Human Genetic Variation, Hiv-1 Sequence Diversity, And Viral Control, Istvan Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. Mclaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio Lopez-Galindez, Concepcion Casado, Andri Rauch, Huldrych F. Gunthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltan Kutalik, Todd M. Allen, Viktor Muller, P. Richard Harrigan, David Heckerman, Amalio Telenti, Jacques Fellay

Biology Faculty Articles

HIV-1 sequence diversity is affected by selection pressures arising from host genomic factors. Using paired human and viral data from 1071 individuals, we ran >3000 genome-wide scans, testing for associations between host DNA polymorphisms, HIV-1 sequence variation and plasma viral load (VL), while considering human and viral population structure. We observed significant human SNP associations to a total of 48 HIV-1 amino acid variants (p<2.4 × 10⁻¹²). All associated SNPs mapped to the HLA class I region. Clinical relevance of host and pathogen variation was assessed using VL results. We identified two critical advantages to the use of viral variation …

Exploring Life And Death At The Cellular Level: An Examination Of How Our Cells Can Live Without Us, Emily F. Schmitt Lavin

Quadrivium: A Journal of Multidisciplinary Scholarship

During the academic year (2012–2013) students and faculty in the Farquhar College of Arts and Sciences focused on the annual theme of “Life and Death.” To this end, we have been focusing all aspects of academic growth around this theme. It has guided our coursework, study groups, invited lecture series, Faculty Lecture Series, and even our Commencement speaker’s address (Farquhar College of Arts and Sciences, 2013). In this paper the idea of life and death will be examined from a cellular and molecular level, and the idea of what happens to our biological pieces (cells, proteins, tissues, etc.) once they …

From The Editors, Eric Mason, Andrea E. Shaw-Nevins

Quadrivium: A Journal of Multidisciplinary Scholarship

No abstract provided.

Prospective Elementary Teachers’ Views On Their Teachers And Their Effectiveness, Mehmet Karakas

The Qualitative Report

In this paper future elementary teachers reflect on their past experiences and talk about their teachers and the way they were taught, and portray the characteristics of effective and not so effective teachers. The study also highlights Turkish teachers` way of instruction and the strategies they use. Participants were 41 sophomore and 62 junior prospective elementary teachers enrolled in a small university in northeastern Turkey. Data were collected using mostly the document analysis techniques. Findings show that effective teachers are caring, loving, funny, and patient, show special in and out of class interest in students, and are fair to everyone. …

The Current Volume 24 : Issue 9, Nova Southeastern University

Student Newspapers

No abstract provided.

Bobby Fischer In Socio-Cultural Perspective: Application Of Hiller’S (2011) Multi-Layered Chronological Chart Methodology, Jospeh G. Ponterotto, Jason D. Reynolds

The Qualitative Report

This article presents a case study application of Hiller’s (2011) Multi - Layered Chronological Chart (MLCC) methodology to the life story of former World Chess Champion Bobby Fischer. Designed for use in qualitative biographical studies, the MLCC is adapted here for psychobiographical research. In 1972, Fischer became an American Cold War hero as he wrestled the World Chess Championship from a half century of Soviet domination. His rapid rise to world fame was followed by infamy as Fischer abandoned competitive chess, grew increasingly Anti - Semitic and Anti - American, became a fugitive from U.S. justice, and died in relative …

Playing Set® To Discover Qualitative Data Analysis, Jean Scandlyn, Sarah Hautzinger

The Qualitative Report

This article describes the use of an experiential classroom exercise using the card game Set® to introduce concepts related to qualitative approaches to research design and analysis, particularly those based in an interpretive framework. The multiple components of the game, which centers on visual pattern recognition, parallel the “organic” complexity of ethnographic investigation and demonstrate how strong interpretations can be supported with qualitative evidence. The first author adapted the exercise, originally developed by the second author for teaching undergraduate anthropology students, for use in workshops teaching qualitative research to mid - career professionals working on health - related projects in …

The Current Volume 24 : Issue 7, Nova Southeastern University

Student Newspapers

No abstract provided.

The Sexy Issue: Visual Expressions Of Heteronormativity And Gender Identities In Cosmopolitan Magazine, Michael J. Saraceno, Rachel B. Tambling

The Qualitative Report

The current study used a qualitative image analysis to explore observed interactional behaviors communicated through images printed in Cosmopolitan magazine during the calendar year of 2009 as a means to infer social values . Two general inquiries were used to guide the manner with which behavior was observed: is a heteronormative bias present and what values regarding the expressions of sexual orientation and gender identities can be inferred from these images. The sample consisted of 722 individual images depicting groups of two or more persons. Images were coded for group gender composition, activities engaged in, and physical touch . Results …

The Repetitive Component Of The Sunflower Genome As Shown By Different Procedures For Assembling Next Generation Sequencing Reads, Lucia Natali, Rosa Maria Cossu, Elena Barghini, Tommaso Giordani, Matteo Buti, Flavia Mascagni, Michele Morgante, Navdeep Gill, Nolan Kane, Loren Rieseberg, Andrea Cavallini

Biology Faculty Articles

Background

Next generation sequencing provides a powerful tool to study genome structure in species whose genomes are far from being completely sequenced. In this work we describe and compare different computational approaches to evaluate the repetitive component of the genome of sunflower, by using medium/low coverage Illumina or 454 libraries.

Results

By varying sequencing technology (Illumina or 454), coverage (0.55 x-1.25 x), assemblers and assembly procedures, six different genomic databases were produced. The annotation of these databases showed that they were composed of different proportions of repetitive DNA families. The final assembly of the sequences belonging to the six databases …

Com Outlook Fall 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

2013 Survey Of Juvenile Law, Michael J. Dale

Faculty Scholarship

No abstract provided.

Allied Health Students’ Perceptions Of Class Difficulty: The Case Of Undergraduate Human Anatomy And Physiology Classes, Diana Sturges, Trent Mauner

Internet Journal of Allied Health Sciences and Practice

Purpose: The Human Anatomy and Physiology (HAP) course is required of all allied health majors. Students need to earn a grade of “C” or better, and many students find this class academically challenging. This study investigated allied health students’ perceptions of what makes the undergraduate class difficult. Methods: A 28-question survey targeted 403 students enrolled in three HAP sections taught by the same instructor. Results: Students returned 279 surveys (68% return rate). Qualitative and quantitative data supported a three factor model in making this class difficult: discipline, student, and teaching related factors. Students consider that discipline factors are more important …

Pharmacological Characterization Of A Novel Non-At1, Non-At2 Angiotensin Binding Site Identified As Neurolysin, Jamala D. Swindle, Kira L. Santos, Robert C. Speth

HPD Articles

The discovery of a novel non-AT1, non-AT2 binding site for angiotensins in the rodent brain and testis that is unmasked by the organomercurial compound para-chloromercuribenzoic acid (PCMB) has catalyzed efforts to purify and characterize this protein. We recently reported that this protein is neurolysin and now report upon the specificity of this binding site for various neuropeptides. Competition binding assays in rat brain and testis used (125)I-Sar(1), Ile(8) angiotensin II (Ang II) as the radioligand in the presence of saturating concentrations of AT1 and AT2 receptor antagonists and 100 μM parachloromercuribenzoate. Primary screening of 36 peptides and other compounds at …

Trick Or Treat: The Application Of The State Udap Statutes To Government Agencies In The Florida Dependency Process, Michael Flynn

Faculty Scholarship

No abstract provided.

Accuracy Assessment Of Noaa's Florida Keys Benthic Habitat Map, Brian K. Walker, Ian Rodericks, Amanda Costaregni

Marine & Environmental Sciences Faculty Reports

This report describes the methodologies, analyses, and results for an independent accuracy assessment of a thematic benthic habitat map produced by NOAA for the Florida Keys. It is an analysis of four regional accuracy assessments. Over the course of the Florida Keys mapping project, NOAA amended part of the classification scheme. The original scheme for mapping benthic cover was a tiered approach where certain benthic cover categories were given priority over others (e.g. coral was most important). Recently, this was modified to a dominant benthic cover scheme where the habitat is characterized by the single most dominant cover type and …

Nomenclatural Transfers In The Pantropical Genus Myrsine (Myrsinaceae), Jon M. Ricketson, John J. Pipoly Iii

Marine & Environmental Sciences Faculty Articles

The names of 14 taxa of Rapanea Aubl. are transferred to Myrsine L. (Myrsinaceae). The 14 new combinations include: M. acutiloba (Mez) Ricketson & Pipoly [≡ R. acutiloba Mez]; M. amischocarpa (A. C. Sm.) Ricketson & Pipoly [≡ R. amischocarpa A. C. Sm.]; M. boivinii (Mez) Ricketson & Pipoly [≡ R. boivinii Mez]; M. comorensis (Mez) Ricketson & Pipoly [≡ R. comorensis Mez]; M. courboniana (Mez) Ricketson & Pipoly [≡ R. courboniana Mez]; M. crassiramea (A. C. Sm.) Ricketson & Pipoly [≡ R. crassiramea A. C. Sm.]; M. daphnoides (Mez) Ricketson & Pipoly [≡ R. daphnoides Mez]; M. forbesii (Mez) …

Evaluation Of Factors That Increase The Severity Of Dysmenorrhoea Among University Female Students In Maiduguri, North Eastern Nigeria, Roland Nnaemeka Okoro, Helen Malgwi, Glory Ogechi Okoro

Internet Journal of Allied Health Sciences and Practice

Dysmenorrhoea is defined as painful menses in women.1 Dysmenorrhoea is frequently encountered in young women around adolescence. It affects the quality of life (QOL) of women during reproductive age. The aetiology of primary dysmenorrhoea is not precisely understood, but most symptoms can be explained by the action of uterine prostaglandins, particularly PG F2α. It may be associated with other symptoms such as nausea, vomiting, diarrhoea, back pain, fatigue, headache, dizziness, and fainting. These symptoms could be very severe and social activity is very limited during menstruation, reducing quality of life in women. Severity of symptoms is usually assessed by grading …

Promoting Health And Wellbeing For People With Attention Deficit Hyperactivity Disorder: An Occupational Perspective, Danielle Hitch, Negar Lavasani, Genevieve Pepin, Karen Stagnitti

Internet Journal of Allied Health Sciences and Practice

Purpose: To provide an overview of current knowledge and practice that supports an occupational perspective to health promotion for people with attention deficit hyperactivity disorder (ADHD).Method: Evidence was identified from a range of electronic databases using inclusion and exclusion criteria. Studies were subjected to a process of critical appraisal using scales for both quantitative and qualitative research, with only those ranked in the top four levels included. The scales used for this critique were the levels of evidence for quantitative research defined by the Australian National Health and Medical Research Council (NHMRC) and the Rosalind Franklin Qualitative Research Appraisal Instrument …

Exploring Life And Death At The Cellular Level: An Examination Of How Our Cells Can Live Without Us, Emily F. Schmitt Lavin

Biology Faculty Articles

No abstract provided.

The Current Volume 24 : Issue 5, Nova Southeastern University

Student Newspapers

No abstract provided.

Surviving: One Family’S Experience With Cancer, Jennifer M. Denmon

The Qualitative Report

People experience trauma in many ways. Discussing the trauma in the form of illness narratives can be beneficial, not only to the patient, but for their families as well (Hydén, 1997). Illness narratives are becoming more popular in the medical field, but mostly are written from the perspective of the patient and their spouse. Little is written from the perspective of the children. In this article, my immediate family and I write our narratives detailing the experience of my father’s cancer. Major themes that emerged from our stories are disbelief, unreliable memories, wanting to forge ahead, and a stronger family. …

Migratory Patterns And Habitat Use Of The Sand Tiger Shark (Carcharias Taurus) In The Western North Atlantic Ocean, Shara Marie Teter

HCNSO Student Theses and Dissertations

Large population declines for sand tiger sharks (Carcharias taurus) in parts of its global range are well documented, resulting in a strong need for biologically informed conservation and management measures. Although sand tigers in the western North Atlantic have been listed as a Species of Concern by the US government since 1997, details of their seasonal migratory movements and especially vertical habitat use patterns along the US East Coast are limited. Understanding these movement patterns is vital to reducing fishery-related mortality of these sharks and informing other management efforts aimed at recovery of their stocks in the US Atlantic. …

The Current Volume 24 : Issue 4, Nova Southeastern University

Student Newspapers

No abstract provided.

The Tiger Genome And Comparative Analysis With Lion And Snow Leopard Genomes, Yun Sung Cho, Li Hu, Haolong Hou, Hang Lee, Jiaohui Xu, Soowhan Kwon, Sukhun Oh, Hak-Min Kim, Sungwoong Jho, Sangsoo Kim, Young-Ah Shin, Byung Chul Kim, Hyunmin Kim, Chang-Uk Kim, Shu-Jin Luo, Warren E. Johnson, Klaus-Peter Koepfli, A. Schmidt-Kunzel, Jason A. Turner, L. Marker, Cindy K. Harper, Susan M. Miller, Wilhelm Jacobs, Laura D. Bertola, Tae Hyung Kim, Sunghoon Lee, Qian Zhou, Hyun-Ju Jung, Xiao Xu, Priyvrat Gadhvi, Pengwei Xu, Yingqi Xiong, Yadan Luo, Shengkai Pan, Caiyun Gou, Xiuhui Chu, Jilin Zhang, Sanyang Liu, Jing He, Ying Chen, Linfeng Yang, Yulan Yang, Jiaju He, Sha Liu, Junyi Wang, Chul Hong Kim, Hwanjong Kwak, Jong-Soo Kim, Seungwoo Hwang, Junsu Ko, Chang-Bae Kim, Sangtae Kim, Damdin Bayarlkhagva, Woon Kee Paek, Seong-Jin Kim, Stephen J. O'Brien, Jun Wang, Jong Bhak

Biology Faculty Articles

Tigers and their close relatives (Panthera) are some of the world’s most endangered species. Here we report the de novo assembly of an Amur tiger whole-genome sequence as well as the genomic sequences of a white Bengal tiger, African lion, white African lion and snow leopard. Through comparative genetic analyses of these genomes, we find genetic signatures that may reflect molecular adaptations consistent with the big cats’ hypercarnivorous diet and muscle strength. We report a snow leopard-specific genetic determinant in EGLN1 (Met39>Lys39), which is likely to be associated with adaptation to high altitude. We also detect a …

A Qualitative Exploration Of Emerging Adults’ And Parents’ Perspectives On Communicating Adulthood Status, Jessica F. Jablonski, Sara Dettinger Martino

The Qualitative Report

In this study the authors examine parent - child communication in Emerging Adulthood. Thirty - seven college students and one or both of their parents completed written questionnaires assessing whether the parent had verbally communicated or did some action to acknowledge the Emerging Adult’s maturity. Communication about changes in the parent - child relationship, as well as the Emerging Adult’s decision - making abilities, obligations to the family, and financial responsibilities were also assessed. The responses to the open ended questions were qualitatively analyzed using grounded theory. The findings indicated that the Emerging Adults’ and parents’ responses were very similar, …

Buoy Gear- A Potential For Bycatch Reduction In The Small-Scale Swordfish Fisheries: A Florida Experience And Indian Ocean Perspective., Evgeny V. Romanov, David W. Kerstetter, Travis Allan Moore, Pascal Bach

Marine & Environmental Sciences Faculty Proceedings, Presentations, Speeches, Lectures

A swordfish buoy gear, an innovative fishing practice developed in USA in early 2000s, provide a possibility of direct swordfish targeting yielding high CPUE of target species and very low bycatch levels. Here we present a summary of US experience and discuss potential application of this gear in the Indian Ocean region in the perspective of small-scale fisheries development and bycatch reduction.

Shared Mycobacterium Avium Genotypes Observed Among Unlinked Clinical And Environmental Isolates, M. Ashworth Dirac, Kris M. Weigel, Mitchell A. Yakrus, Annie L. Becker, Hui-Ling Chen, Gina Fridley, Arthur Sikora, Cate Speake, Elizabeth D. Hilborn, Stacy Pfaller, Gerard A. Cangelosi

Chemistry and Physics Faculty Articles

Our understanding of the sources of Mycobacterium avium infection is partially based on genotypic matching of pathogen isolates from cases and environmental sources. These approaches assume that genotypic identity is rare in isolates from unlinked cases or sources. To test this assumption, a high-resolution PCR-based genotyping approach, large-sequence polymorphism (LSP)-mycobacterial interspersed repetitive unit–variable-number tandem repeat (MIRU-VNTR), was selected and used to analyze clinical and environmental isolates of M. avium from geographically diverse sources. Among 127 clinical isolates from seven locations in North America, South America, and Europe, 42 genotypes were observed. Among 12 of these genotypes, matches were seen in …

A Pre-Zygotic Barrier To Hybridization In Two Con-Generic Species Of Scleractinian Corals, Andrew H. Baird, Vivian R. Cumbo, Joana Figueiredo, Saki Harii

Marine & Environmental Sciences Faculty Articles

Hybridization is often cited as a potential source of evolutionary novelty in the order Scleractinia. While hybrid embryos can be produced in vitro, it has been difficult to identify adult hybrids in the wild. Here, we tested the potential for hybridization between two closely related species in the family Fungiidae. We mixed approximately 5000 eggs of Ctenactis echinata with sperm from C. crassa. No hybrid embryos were produced. This observation adds to a growing body of evidence for pre-zygotic barriers to hybridization in corals and challenges the claim that hybridization is a major source of evolutionary novelty …

The Current Volume 24 : Issue 2, Nova Southeastern University

Student Newspapers

No abstract provided.