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Articles 2791 - 2820 of 7452
Full-Text Articles in Entire DC Network
Genomic Analysis Of Acropora Cervicornis Mucus And Sediments In The Florida Keys Tavernier Nursery, Rachel Zimmerman
Genomic Analysis Of Acropora Cervicornis Mucus And Sediments In The Florida Keys Tavernier Nursery, Rachel Zimmerman
HCNSO Student Theses and Dissertations
White Band disease has devastated the staghorn coral Acropora cervicornis in recent decades, and it continues to impinge upon restoration efforts. The etiological agent(s) remain unknown as Koch’s postulates have yet to be satisfied, but disease may originate when opportunistic pathogens in the surface mucus layer exploit a stressed host. Using 16s rRNA sequencing, differences in the taxonomic diversity and relative abundances of bacteria within the mucus of A. cervicornis were documented between colonies of the same genotype, genotypes (n=8) categorized as having either high or low WBD susceptibility, and during a transplantation event. A. cervicornis colonies suspended from midwater …
A Comparison Of Benthic Habitats And Faunas Between The Miami Terrace (Proposed Calypso Pipeline Site) And The Pourtales Terrace (Coral Habitat Of Particular Concern), Laura Dell
HCNSO Student Theses and Dissertations
Quantitative photographs of benthic communities at two northern Miami Terrace sites, originally investigated as part of an environmental impact survey in advance of the proposed Calypso pipeline, and two Pourtalès Terrace sites, investigated as part of an exploration of deep-sea coral and sponge ecosystems (DSCEs) within the Pourtalès Terrace Deep-water Coral Habitat Area of Particular Concern (CHAPC), were reanalyzed and compared for similarities and differences. Both terraces are part of an elongated lithified platform that parallels the southeastern Florida coast at depths averaging between 250 and 450 m. Although both sites have similar geological origins and lie under the Florida …
Next Generation Sequencing Methods For Coastal Zone Water Quality Monitoring, Catherine Iskrenko
Next Generation Sequencing Methods For Coastal Zone Water Quality Monitoring, Catherine Iskrenko
HCNSO Student Capstones
When analyzing the water quality of the coastal zone, culture-based techniques have been utilized most often to identify Fecal Indicator Bacteria in samples. Since the advent of the Sanger Method for DNA sequencing, other techniques have arisen that provide significantly more information on the microorganisms in sample, but they are still not the mainstream for water quality analysis. This capstone reviews and compares culture-based techniques, DNA sequencing, RNA sequencing, qPCR for biomarker, and 16S rDNA sequencing to highlight their merits and shortcomings for analyzing environmental water samples. The technique presented that provides the broadest range of information (including the identification …
Meta-Analytic Summary Of Parasites And Diseases Of Elasmobranchs Found In Florida Waters, Alexis S. Modzelesky
Meta-Analytic Summary Of Parasites And Diseases Of Elasmobranchs Found In Florida Waters, Alexis S. Modzelesky
HCNSO Student Capstones
Elasmobranchs have conservational and commercial importance. There is a need for a more complete understanding of their health, due to their ability to shape trophic webs and their money-making potential with fishers and ecotourists. Sharks have been known to influence the strength of food webs, including reef ecosystems where many fish species are harvested for food. The investigation of pathogenic agents and diseases in elasmobranchs has been biased to favor those natural enemies that inhabit the digestive system and epidermal surfaces. Certain groups of parasites such as cestodes, copepods, and monogeneans, were most often recorded in this study. The bacterial …
Microbial Ecology Of South Florida Surface Waters: Examining The Potential For Anthropogenic Influences, Chase P. Donnelly
Microbial Ecology Of South Florida Surface Waters: Examining The Potential For Anthropogenic Influences, Chase P. Donnelly
HCNSO Student Theses and Dissertations
South Florida contains one of the largest subtropical wetlands in the world, and yet not much is known about the microbes that live in these surface waters. These microbes play an important role in chemical cycling and maintaining good water quality for both human and ecosystem health. The hydrology of Florida’s surface waters is tightly regulated with the use of canal and levee systems run by the US Army Corps of Engineers and The South Florida Water Management District. These canals run through the Everglades, agriculture, and urban environments to control water levels in Lake Okeechobee, the Water Conservation Areas, …
Using Expert Interviews Within Modes In Online And Offline Spaces To Extend Comprehensive Literature Review Processes, Alana Morris, Anthony J. Onwuegbuzie, Hannah R. Gerber
Using Expert Interviews Within Modes In Online And Offline Spaces To Extend Comprehensive Literature Review Processes, Alana Morris, Anthony J. Onwuegbuzie, Hannah R. Gerber
The Qualitative Report
In this article, we explore a 7-step process for conducting a comprehensive literature review (CLR). Specifically, after describing each of the steps, we explain the importance of expanding the search beyond traditional databases through 5 multimodal tasks that Onwuegbuzie and Frels (2016) refer to as MODES (Media, Observations, Documents, Experts, and Secondary Data), which can be undertaken separately, or which may interact with each other. Then, we highlight and provide an exemplar process for the Experts task, which motivates researchers to identify, to seek out, and to interview 1 or more experts associated with their research question(s). Furthermore, we illustrate …
Interpersonal Hardiness As A Critical Contributing Factor To Persistence Among International Women In Doctoral Programs: A Trioethnographic Study, Eraldine S. Williams-Shakespeare 2153760, Joyce E. Bronteng, Adhwaa Alahmari
Interpersonal Hardiness As A Critical Contributing Factor To Persistence Among International Women In Doctoral Programs: A Trioethnographic Study, Eraldine S. Williams-Shakespeare 2153760, Joyce E. Bronteng, Adhwaa Alahmari
The Qualitative Report
Women in PhD programs, in particular minority and international women, are especially at risk for drop-out (Castro, Garcia, Cavazos, & Castro, 2011; Haynes et al., 2012). This initial part of a longitudinal trioethnography captures the experiences of three international women in a doctoral program, highlighting the challenges, support systems, and coping mechanisms they engage with in the process of completing their degrees. Discoveries include the identification of “Interpersonal Hardiness” as the potential vehicle which could ensure our success.
Antipredatory Escape Behaviors Of Two Benthic Ctenophores In South Florida, Peter W. Glynn, Brian Coffman, Jeongran Vanderwoude, Nicolas Martinez, Joshua H. Dominguez, Julie M. Gross, Dorothy-Ellen A. Renegar
Antipredatory Escape Behaviors Of Two Benthic Ctenophores In South Florida, Peter W. Glynn, Brian Coffman, Jeongran Vanderwoude, Nicolas Martinez, Joshua H. Dominguez, Julie M. Gross, Dorothy-Ellen A. Renegar
Marine & Environmental Sciences Faculty Articles
Benthic ctenophores, members of the family Coeloplanidae (Order Platyctenida, Phylum Ctenophora) are more widespread and abundant in tropical and subtropical marine environments than formerly recognized. Coeloplanid ctenophores are members of the most speciose family of benthic ctenophores, with 33 recognized species of Coeloplana and one species of the genus Vallicula (Mills 1998). The majority of coeloplanids are ectosymbionts of algae and diverse benthic invertebrates (Matsumoto 1999, Alamaru et al. 2015). Hundreds to thousands of individuals can occupy preferred habitats in < 1 m2 of substrate patches. Galt (1998) noted Vallicula multiformis inhabiting algae in Hawaii at population densities as high as 10,000 …
Creating A Participatory Arts-Based Online Focus Group: Highlighting The Transition From Docmama To Motherscholar, Anna Cohenmiller
Creating A Participatory Arts-Based Online Focus Group: Highlighting The Transition From Docmama To Motherscholar, Anna Cohenmiller
The Qualitative Report
Using Facebook to create a participatory, arts-based online focus group, this study had two primary purposes: (1) to examine how mothers in academia present themselves as they transition from doctoral student mother (“DocMama”) to full time position as motherscholars and (2) to explore the use of a participatory, arts-based online focus group on Facebook to facilitate participant description of experiences and feelings. This study adds both to the research on online research by emphasizing a collaborative nature and art to share experiences, and also to the research about motherscholars, examining the oft overlooked transition from doctoral program to academic career …
Parasitic Indicators Of Foraging Strategies In Wading Birds, Sarah Gumbleton
Parasitic Indicators Of Foraging Strategies In Wading Birds, Sarah Gumbleton
HCNSO Student Theses and Dissertations
Feeding ecology and trophic interactions of six species of wading birds were explored through a combined analysis of stable isotope profiles and endoparasite communities. Stable isotopes broadly characterize the feeding preferences and geographic information, while parasite communities reflect long-term trends in feeding ecology. Deceased birds were obtained from four South Florida wildlife rehabilitation organizations. Of the 81 birds dissected, 73 contained parasites. Parasites were predominately found within the gastrointestinal tract. Host and range extensions were noted for several parasite taxa. Bird host species had a significant effect on the parasite community (P=0.001) while wildlife center location and maturity status did …
Koreans, Americans, Or Korean-Americans: Transnational Adoptees As Invisible Asians, A Book Review, Tairan Qiu
Koreans, Americans, Or Korean-Americans: Transnational Adoptees As Invisible Asians, A Book Review, Tairan Qiu
The Qualitative Report
The book, Invisible Asians: Korean American Adoptees, Asian American Experiences, and Racial Exceptionalism, explores the personal narratives and histories of adult adoptees who were born between 1949 and 1983 and who were adopted from Korea by White parents. Using oral history ethnography, Nelson (2016) seeks to correct, complicate, and contribute to current discussions about transnational adoptions. In this book review, the author provides an overview, a personal reflection, and recommendations for potential audiences of this book.
Applications Of Click Chemistry In The Development Of Hiv Protease Inhibitors, Mukesh Madan Mudgal, Nagaraju Birudukota, Mayur A. Doke
Applications Of Click Chemistry In The Development Of Hiv Protease Inhibitors, Mukesh Madan Mudgal, Nagaraju Birudukota, Mayur A. Doke
Chemistry and Physics Faculty Articles
Acquired Immunodeficiency Syndrome (AIDS) has been devastating for millions of people around the world. Inhibition of the human immunodeficiency virus (HIV) protease is among the most important approaches for the therapeutic intervention in HIV infection. Since the discovery of the HIV-1 protease, this enzyme has been considered as a key target for the inhibition of viral replication. A large body of research has been done to develop an effective HIV-1 protease inhibitor. There are to date 10 HIV-1 protease inhibitor drugs approved by the Food and Drug Administration (FDA) that have improved the survival and quality of life of HIV …
Elderly Patients’ Perception Of Pain Management After Open And Reduction Internal Fixation Surgery, Sharon M. Whyte-Daley
Elderly Patients’ Perception Of Pain Management After Open And Reduction Internal Fixation Surgery, Sharon M. Whyte-Daley
The Qualitative Report
Little is known about pain and pain management in older adults who experience open reduction and internal fixation (ORIF) surgery. This qualitative descriptive phenomenological study explored two research questions: (a) What are the perceptions of pain and pain management in patients between 65 and 75 years of age, 48 hours after ORIF surgery in a community hospital? (b) What are the perceptions of adaptation after ORIF? A pilot study included four patients in two units of a Southern California hospital, followed by open ended, semi-structured interviews with 10 participants. Four themes emerged: (a) elderly patients experience different patterns of pain …
Visual Inspection Of Sequential Data: A Research Instrument For Qualitative Data Analysis, Alaa A. Aldahdouh
Visual Inspection Of Sequential Data: A Research Instrument For Qualitative Data Analysis, Alaa A. Aldahdouh
The Qualitative Report
Sequence analysis has been widely used to investigate the patterns of similarities and differences of sequential data in biology and sociology. However, the debate on the usage of sequence analysis in social sciences has not been settled yet. Among a long list, sequence analysis methods have been criticized for ignoring the qualitative information behind the sequences. This paper presents a new instrument for inspecting sequential data visually in qualitative studies. The method includes building a hierarchical tree of relations among the categories which is then used to recode the categories systematically. The recoding process is meant to give meaning to …
Analytical “Bake-Off” Of Whole Genome Sequencing Quality For The Genome Russia Project Using A Small Cohort For Autoimmune Hepatitis, Daria V. Zhernakova, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, Pavel Dobrynin, Andrey A. Yurchenko, Valentin Shimansky, Irina V. Shcherbakova, Andrey S. Glotov, David L. Valle, Minzhong Tang, Emilia Shin, Kathleen B. Schwarz, Stephen James O'Brien
Analytical “Bake-Off” Of Whole Genome Sequencing Quality For The Genome Russia Project Using A Small Cohort For Autoimmune Hepatitis, Daria V. Zhernakova, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, Pavel Dobrynin, Andrey A. Yurchenko, Valentin Shimansky, Irina V. Shcherbakova, Andrey S. Glotov, David L. Valle, Minzhong Tang, Emilia Shin, Kathleen B. Schwarz, Stephen James O'Brien
Biology Faculty Articles
A comparative analysis of whole genome sequencing (WGS) and genotype calling was initiated for ten human genome samples sequenced by St. Petersburg State University Peterhof Sequencing Center and by three commercial sequencing centers outside of Russia. The sequence quality, efficiency of DNA variant and genotype calling were compared with each other and with DNA microarrays for each of ten study subjects. We assessed calling of SNPs, indels, copy number variation, and the speed of WGS throughput promised. Twenty separate QC analyses showed high similarities among the sequence quality and called genotypes. The ten genomes tested by the centers included eight …
Spatiotemporal Change In The Benthic Community Of Southeast Florida, Nicholas P. Jones
Spatiotemporal Change In The Benthic Community Of Southeast Florida, Nicholas P. Jones
HCNSO Student Theses and Dissertations
High-latitude reefs have been postulated as refugia, centers for resilience or the first areas to undergo re-organization under climate change. The Southeast Florida Reef Tract (SEFRT) is a high-latitude reef system (>25 °N) running parallel to the highly urbanized coastline of southeast Florida. With a benthic community comprised of a mixture of coral reef associated assemblages, the SEFRT is towards the northern limit of stony coral cover due to temperature constraints. This study analyzed spatial variations in benthic cover, spatiotemporal changes in the benthic community and the impact of spatial and temporal fluctuations in temperature on benthic cover on …
Presence/Absence And Density Data For Epipelagic Tows Collected During R/V Blazing Seven Cruises Lf2016a And Lf2016b, Northern Gulf Of Mexico From 2016-06-09 To 2016-07-28, Jay R. Rooker, David Wells
Presence/Absence And Density Data For Epipelagic Tows Collected During R/V Blazing Seven Cruises Lf2016a And Lf2016b, Northern Gulf Of Mexico From 2016-06-09 To 2016-07-28, Jay R. Rooker, David Wells
DEEPEND Datasets
This dataset reports presence/absence and density data for epipelagic tows collected in the northern Gulf of Mexico during R/V Blazing Seven cruises LF2016A and LF2016B (2016-06-09 to 2016-07-28). Larval fishes were sampled from 48 stations and cruise data were collected at each site including latitude/longitude, date, time, environmental data (temperature, salinity, dissolved oxygen) and Sargassum dry weight. Larval catch data before and after the oil spill will be compared to improve our understanding of the causes of temporal variability as it relates to the Deep-Water Horizon oil spill (DWHOS). Habitat associations of selected taxa (billfishes, tunas, dolphinfishes, flyingfishes) will be …
Effects Of Ocean Warming, Sedimentation, And Parental Genotype On The Post-Settlement Survival And Growth Of Acropora Cervicornis Recruits, Jena Robbins
HCNSO Student Theses and Dissertations
Ocean warming and increased sedimentation from coastal activities are major threats to coral persistence. This study assessed the effects of increased temperature and sedimentation on the survival and growth of Acropora cervicornisrecruits. The potential for adults from different regions and genotypes to confer their offspring with higher or lower tolerance to heat and/or sediment was also determined. Gametes were collected and brought to the laboratory for cross fertilization of different genotypes within the regions collected. Larval rearing and settlement were then performed in the laboratory. Newly settled recruits were reared at 29 and 31°C (current summer temperature for August …
Being Māori And Pākehā: Methodology And Method In Exploring Cultural Hybridity, Niki Grennell-Hawke (Ngai Tahu, Ngai Mutunga), Keith Tudor Dr
Being Māori And Pākehā: Methodology And Method In Exploring Cultural Hybridity, Niki Grennell-Hawke (Ngai Tahu, Ngai Mutunga), Keith Tudor Dr
The Qualitative Report
This article addresses the first author’s experience of identifying as both Māori and Pākehā in Aotearoa New Zealand. Based on her own research using both kaupapa research theory and heuristic research method, and supervised by the second author, the article describes her negotiation of the experience of being a hybrid cultural subject and object, of belonging and not belonging. The article extends the practice and understanding of cross-cultural research on a number of levels: the intrapsychic (i.e., within the principal investigator herself), the interpersonal (i.e., between the researcher and supervisor), and the methodological (i.e., between an indigenous and a Western …
National Coral Reef Management Fellows Newsletter Volume 2 | Issue 1, National Oceanic And Atmospheric Administration (Noaa) Coral Reef Conservation Program
National Coral Reef Management Fellows Newsletter Volume 2 | Issue 1, National Oceanic And Atmospheric Administration (Noaa) Coral Reef Conservation Program
National Coral Reef Management Fellowship Newsletter
No abstract provided.
Differential Preservation Of Endogenous Human And Microbial Dna In Dental Calculus And Dentin, Allison E. Mann, Susanna Sabin, Kirsten Ziesemer, Ashild J. Vagene, Hannes Schroeder, Andrew T. Ozga, Krithivasan Sankaranarayanan, Courtney A. Hofman, James A. Fellows Yates, Domingo C. Salazar-Garcia, Bruno Frohlich, Mark Aldenderfer, Menno Hoogland, Christopher Read, George R. Milner, Anne C. Stone, Cecil M. Lewis Jr., Johannes Krause, Corinne Hofman, Kirsten I. Bos, Christina Warinner
Differential Preservation Of Endogenous Human And Microbial Dna In Dental Calculus And Dentin, Allison E. Mann, Susanna Sabin, Kirsten Ziesemer, Ashild J. Vagene, Hannes Schroeder, Andrew T. Ozga, Krithivasan Sankaranarayanan, Courtney A. Hofman, James A. Fellows Yates, Domingo C. Salazar-Garcia, Bruno Frohlich, Mark Aldenderfer, Menno Hoogland, Christopher Read, George R. Milner, Anne C. Stone, Cecil M. Lewis Jr., Johannes Krause, Corinne Hofman, Kirsten I. Bos, Christina Warinner
Biology Faculty Articles
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it has been proposed that dental calculus may provide a more robust environment for DNA preservation than other skeletal remains, but this has not been systematically tested. In this study, shotgun-sequenced data from paired dental calculus and dentin samples from 48 globally distributed individuals are compared using a metagenomic approach. Overall, we find DNA from dental calculus is consistently more abundant and less contaminated than DNA from dentin. The majority of DNA in dental calculus is …
Inventory Of Oceanic Fauna Data Including Species, Weight, And Measurements From R/V Point Sur (Cruise Dp05) In The Gulf Of Mexico From 2017-05-01 To 2017-05-11, April Cook, Tracey Sutton
Inventory Of Oceanic Fauna Data Including Species, Weight, And Measurements From R/V Point Sur (Cruise Dp05) In The Gulf Of Mexico From 2017-05-01 To 2017-05-11, April Cook, Tracey Sutton
DEEPEND Datasets
This dataset includes an inventory of Gulf of Mexico oceanic fauna data including species, weight, and measurements collected from R/V Point Sur (Cruise DP05) from 2017-05-01 to 2017-05-11. The main gear type used was a 10-m2 Multiple Opening Closing Net and Environmental Sensing System (MOCNESS). The MOCNESS was fitted with 6 nets which were opened according to the following depth scheme: net 0 from the surface to 1500m, net 1 from 1500-1200m, net 2 from 200-1000m, net 3 from 1000-600m, net 4 from 600-200m, and net 5 from 200m to the surface. Two trawls were conducted at each station sampled …
Ongoing Transposon-Mediated Genome Reduction In The Luminous Bacterial Symbionts Of Deep-Sea Ceratioid Anglerfishes, Tory Hendry, Lindsay L. Freed, Dana Fadera, Dante Fenolio, Tracey Sutton, Jose Lopez
Ongoing Transposon-Mediated Genome Reduction In The Luminous Bacterial Symbionts Of Deep-Sea Ceratioid Anglerfishes, Tory Hendry, Lindsay L. Freed, Dana Fadera, Dante Fenolio, Tracey Sutton, Jose Lopez
Marine & Environmental Sciences Faculty Articles
Diverse marine fish and squid form symbiotic associations with extracellular bioluminescent bacteria. These symbionts are typically free-living bacteria with large genomes, but one known lineage of symbionts has undergone genomic reduction and evolution of host dependence. It is not known why distinct evolutionary trajectories have occurred among different luminous symbionts, and not all known lineages previously had genome sequences available. In order to better understand patterns of evolution across diverse bioluminescent symbionts, we de novo sequenced the genomes of bacteria from a poorly studied interaction, the extracellular symbionts from the “lures” of deep-sea ceratioid anglerfishes. Deep-sea anglerfish symbiont genomes are …
Southeast Florida Large (>2 Meter) Diseased Coral Colony Intervention Summary Report, Brian K. Walker, Alysha Brunelle
Southeast Florida Large (>2 Meter) Diseased Coral Colony Intervention Summary Report, Brian K. Walker, Alysha Brunelle
Marine & Environmental Sciences Faculty Reports
No abstract provided.
Past, Present, And Future: Narrative Reflections Of A Novice Researcher, Katie L. Laux
Past, Present, And Future: Narrative Reflections Of A Novice Researcher, Katie L. Laux
The Qualitative Report
In this article, I use an autoethnographical approach to explore how I identified my research interests of student voice, action research, and students as scientific researchers. My purpose was to identify some of the influences on my academic life. To achieve this goal, I used my writing as a method of both data collection and analysis combined with my parents’ interpretations of events to create narratives of my lived experiences. This process allowed me to make sense of how my lived experiences shaped my decision to become a doctoral student and the choices I have made as a novice researcher.
Characterization Of The Bioluminescent Symbionts From Ceratioids Collected In The Gulf Of Mexico, Lindsay L. Freed
Characterization Of The Bioluminescent Symbionts From Ceratioids Collected In The Gulf Of Mexico, Lindsay L. Freed
HCNSO Student Theses and Dissertations
Anglerfishes are easily one of the most popular deep-sea creatures due to their menacing appearance, extreme sexual dimorphism, parasitic mating approach, and eye catching bioluminescent lure. Unlike most bioluminescent fishes, which intrinsically generate light, female anglerfishes belonging to nine of the 11 families within the suborder Ceratioidei (deep-sea anglerfishes) have developed a symbiotic relationship with bioluminescent bacteria that are housed within the light organs. Previous molecular work had identified symbionts from two anglerfish species as novel and possibly unculturable taxa (Haygood et al., 1992), but nothing more has been revealed about the bioluminecent symbionts of ceratioids. As part of …
Hypocrisy And Corruption: How Disparities In Power Shape The Evolution Of Social Control, Omar T. Eldakar, J. Oliver Kammeyer, Nikhil Nagabandi, Andrew C. Gallup
Hypocrisy And Corruption: How Disparities In Power Shape The Evolution Of Social Control, Omar T. Eldakar, J. Oliver Kammeyer, Nikhil Nagabandi, Andrew C. Gallup
Biology Faculty Articles
Altruism presents an evolutionary paradox, as altruistic individuals are good for the group yet vulnerable to exploitation by selfish individuals. One mechanism that can effectively curtail selfishness within groups is punishment. Here, we show in an evolutionary game-theoretical model that punishment can effectively evolve and maintain high levels of altruism in the population, yet not all punishment strategies were equally virtuous. Unlike typical models of social evolution, we explicitly altered the extent to which individuals vary in their power over others, such that powerful individuals can more readily punish and escape the punishment of others. Two primary findings emerged. Under …
Identification Of A Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens, Renee Fleeman, Ginamarie Debevec, Kirsten Antonen, Jessie L. Adams, Radleigh Santos, Greg Welmaker, Richard A. Houghten, Marc Giulianotti, Lindsey N. Shaw
Identification Of A Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens, Renee Fleeman, Ginamarie Debevec, Kirsten Antonen, Jessie L. Adams, Radleigh Santos, Greg Welmaker, Richard A. Houghten, Marc Giulianotti, Lindsey N. Shaw
Mathematics Faculty Articles
We have previously reported the use of combinatorial chemistry to identify broad-spectrum antibacterial agents. Herein, we extend our analysis of this technology toward the discovery of anti-resistance molecules, focusing on efflux pump inhibitors. Using high-throughput screening against multi-drug resistant Pseudomonas aeruginosa, we identified a polyamine scaffold that demonstrated strong efflux pump inhibition without possessing antibacterial effects. We determined that these molecules were most effective with an amine functionality at R1 and benzene functionalities at R2 and R3. From a library of 188 compounds, we studied the properties of 5 lead agents in detail, observing a fivefold to eightfold decrease …
Heavy Metal Accumulation In Seagrasses In Southeastern Florida, Erin Smith
Heavy Metal Accumulation In Seagrasses In Southeastern Florida, Erin Smith
HCNSO Student Theses and Dissertations
Seagrass beds are among the most ecologically important systems in the marine environment. They provide the primary production to nearby coral reef and mangrove communities, and seagrasses comprise a large component of the diets of many marine organisms including fishes, small invertebrate species, and many protected species such as manatees and sea turtles. This consumption provides a pathway for many contaminants to enter the marine food web via the seagrasses. The coastal location of seagrass beds causes them to be especially susceptible to anthropogenic pollution, including accumulation of heavy metals, which has been shown to have many adverse health effects …
2018 Commencement-Graduate College Of Engineering And Computing Halmos College Of Natural Sciences And Oceanography H. Wayne Huizenga College Of Business And Entrepreneurship, Nova Southeastern University
2018 Commencement-Graduate College Of Engineering And Computing Halmos College Of Natural Sciences And Oceanography H. Wayne Huizenga College Of Business And Entrepreneurship, Nova Southeastern University
NSU Commencement Programs
No abstract provided.