Digital Commons Network^™

Resting-State Cerebral Perfusion Patterns: An Exploratory Factor Analysis Of Single-Photon Emission Computed Tomography Clinical Data, Scott Harcourt

Theses and Dissertations

Resting-state (RS) networks (neural regions demonstrating a temporal correlation when a person is not engaged in deliberate activity) are a new topic in neuroscience and neuropsychology, not gaining significant traction in the literature until 2005. Few studies have used single-photon emission computed tomography (SPECT) regional cerebral blood flow (rCBF) to analyze RS. The omission is critical because SPECT RS networks have a different structure and statistical representation than functional magnetic resonance imaging (fMRI) RS networks. Moreover, recent fMRI research has explored RS differences in persons with psychopathology but have not studied brain-behavior assessment with the potential of application of neuropsychological …

Sea Turtle Conservation Program - 2021 Report, Derek Burkholder, Abby Nease

Sea Turtle Nesting Trends Technical Reports

No abstract provided.

Building A Community Of Inquiry Through Interactive Materials: The Interactive Syllabus, Joshua Aaron Jones

Nova Law Review

No abstract provided.

Limiting Iron Acquisition Of E. Coli With Anti-Tonb1 And Antitonb2​, Jose Diaz, Ryan Luib, Seethal Doki

Protein Modeling Reports

The bacteria E Coli infect approximately 200,000 individuals in the United States and can lead to critical illnesses. The transfer of iron from the bloodstream to bacteria is one of the main requirements for the survival. One of the mechanisms to obtain iron by use of siderophores and the protein FhuA was investigated. Undergraduate students grouped into teams to each explain a unique molecular story- modeled in Jmol/Pymol and demonstrated through a poster and PowerPoint. Using the PDB file, 2GRX, a drug to inhibit the TonB-Ton Box interaction which provides the FhuA iron mechanism energy to operate was researched. A …

Comparing The Effectiveness Between Ivacaftor And Glpg 1837, Saimi Vanessa Reyes, Jordan Nichole Carreras, Vibha Sankavaram

Protein Modeling Reports

Cystic fibrosis is an autosomal disease that is caused by a defect in the CFTR, or cystic fibrosis transmembrane conductance regulator. It affects more than 70,000 people world-wide and is life-threatening to those affected. To treat this disease there are two drug classes: correctors and potentiators. Correctors aim to correct the misfolded CFTR proteins, while potentiators aid in increasing ion concentration outside of the cells by keeping the channels open for longer periods of time. The aim of this project was to identify the key differences between two similar potentiator drugs, Ivacaftor (Kalydeco®) and GLPG 1837. The research question posed …

How Can We Design An Inhibitor With An Enhanced Binding Affinity That Is Selective For Mmp12 ?, Aisha Y. Abdool, Lyla Abbas, Tassnime Sebaei, Emily Schmitt, Arthur Sikora

Protein Modeling Reports

Matrix metalloproteinase 12 (MMP 12) is one of the twenty-three members of the peptidase M10 family which are primarily responsible for the breakdown of the extracellular matrix. MMP12 plays a key factor in the degradation of elastin and is commonly studied in the lungs of smokers, where MMP12 digests the elastin and serves as a chemokine to recruit a pro-inflammatory immune response. Thus, MMP12 is a major therapeutic target in wound healing and scar formation following a myocardial infarction. Students from the Honors Protein Modeling class at Nova Southeastern University modeled the interactions between MMP12 and various inhibitors. Using the …

A Match Made In Heaven: Exploring Views Of Medicine Students, Pharmacy Interns And Facilitators In An Interprofessional Medicines Pilot Study, Eileen M. Mckinlay, Melanie Brown, Debbie Wallace, Caroline Morris, Amanda Garnett, Ben Gray

Internet Journal of Allied Health Sciences and Practice

Purpose: To date, few interprofessional education initiatives have included just medicine and pharmacy learners. This research sought to explore learners’ and facilitators’ views of an interprofessional education medicines pilot study involving medical students and pharmacy interns. Methods: Qualitative feedback was gathered from the participating learners and a facilitator focus group was undertaken. Results: Medical student and pharmacy intern learners reported enjoying taking part and found the simulation and overall initiative to be authentic. They described learning most about each other’s roles and responsibilities and about teamwork, collaborative management, and collaboration. Some logistical improvements were suggested. The facilitators judged that the …

2021 Nsu Fact Book, Nova Southeastern University

NSU Fact Book

The 29th edition of the Nova Southeastern University (NSU) Fact Book provides perspective on the university’s character, growth, and accomplishments. The 2021 Fact Book includes narrative, numeric, and graphic representation of the university, including history, characteristics, and development of the institution. Data are presented in both tabular and graphic formats to provide pertinent detail, and general trends are highlighted.

Like all previous editions of the Fact Book, this edition is a snapshot of the university during the academic year that concludes in the year of its publication. Therefore, the 2021 Fact Book represents NSU from fall 2020 through spring …

Unexpected Role Of Communities Colonizing Dead Coral Substrate In The Calcification Of Coral Reefs, Manoela Romanó De Orte, David A. Koweek, Tyler Cyronak, Yuichiro Takeshita, Alyssa Griffin, Kennedy Wolfe, Alina Szmant, Robert Whitehead, Rebecca Albright, Ken Caldeira

Marine & Environmental Sciences Faculty Articles

Global and local anthropogenic stressors such as climate change, acidification, overfishing, and pollution are expected to shift the benthic community composition of coral reefs from dominance by calcifying organisms to dominance by non-calcifying algae. These changes could reduce the ability of coral reef ecosystems to maintain positive net calcium carbonate accretion. However, relationships between community composition and calcification rates remain unclear. We performed field experiments to quantify the metabolic rates of the two most dominant coral reef substrate types, live coral and dead coral substrate colonized by a mixed algal assemblage, using a novel underwater respirometer. Our results revealed that …

Karl Tomm’S Internalized Other Interviewing: From Theory To Practice, Robin Akdeniz

Department of Family Therapy Dissertations and Applied Clinical Projects

Over the last 40 years, the Canadian psychiatrist and family therapist Karl Tomm has been a key contributor to postmodern developments in family therapy (Collins & Tomm, 2009; Strong et al., 2008; Tomm, Hoyt, & Madigan, 2001). This dissertation traces the people, ideas, and practices that have influenced Tomm's approach, providing an in- depth examination of the method he developed for putting his ideas into practice: Internalized Other Interviewing (IOI). A systemic, relational approach to the practice of postmodern family therapy uses language as a means to create change. Family therapists routinely use different types of questions to ask clients …

Sibling Conflict And Caregiving For Aging Parents, Jennifer Elise Lawer

Department of Conflict Resolution Studies Theses and Dissertations

This dissertation presents the results of a grounded theory study of the key factors of sibling conflict when caregiving for an aging parent. Following interviews with 30 participants, I conducted initial coding, focused coding and theoretical coding, which led to the development of a theory that explains the relationship of conflict factors such as: beliefs & values, feelings & emotions, roles & expectations, and behaviors & responses. The dissertation includes a discussion of how birth order theories, power theories and psychodynamic theories apply to sibling conflict. In addition, I discuss how the findings apply to conflict resolution skills and offer …

Sex Based Differences In Trust And Dissent: An Exploration Of Leaders And Followers In Healthcare Management, Jennifer De Zayas Carmean

Department of Conflict Resolution Studies Theses and Dissertations

This dissertation is a quantitative study which looks at the ways in which healthcare followers perceive their leaders regarding gender, over the concepts of trust and organizational dissent. The study was open to members of non-clinical healthcare associations, but clinicians were not specifically excluded. Inferential statistics were inconclusive, as they directly contradict literature that directly correlates trust and dissent in the general business world. Reading subtextual, the outcome indicates possible sublimated conflict between and among both genders, for both followers and leaders. Objectively, women showed more trust in their female leaders, but subjectively this was not true. Indicators in the …

2021-2022 Nsu Undergraduate Student Catalog, Nova Southeastern University

Undergraduate Programs Course Catalogs

No abstract provided.

Shaping The Lives Of Little Ones Developmental Equipment Project, Marilyn Tyre

Occupational Therapy Program Student Theses, Dissertations and Capstones

Premature infants in the Neonatal Intensive Care Unit (NICU) may experience extensive hospitalizations due to prematurity and medical complications requiring interventions to sustain life and support physiological development. NICU staff are often focused on immediate medical concerns for these infants and may not consider the development and play needs for these long term hospitalized infants. Occupational therapists are aware of the importance of play and supporting the parental role and co-occupations between the infant and parents. This capstone paper discusses the Shaping the Lives of Little Ones Developmental Equipment Project for infants, nurses, and parents designed to provide opportunities for …

Childhood Play As A Predictor For Development Of Creative Potential In Adulthood: A Mixed Methods Study, Brittany Nicole Saviers

Occupational Therapy Program Student Theses, Dissertations and Capstones

Previous research has demonstrated the benefits of childhood play and creativity in childhood from either a qualitative or quantitative perspective; yet, questions remain regarding the predictive power of childhood play, specifically what types of toys facilitate competencies such as creative potential in adulthood. Utilizing a mixed methods convergent parallel design, the aim of this research was to explore the relationship between the types of toys frequently used during childhood and adult creative potential. Additionally, utilizing adults’ retrospective play stories, the study sought to understand the contribution of play to human development by identifying how qualitative themes ofchildhood play experiences aligned …

Investigation Of Ant Colony Optimization Implementation Strategies For Low-Memory Operating Environments, Douglas Hale

CCAC Theses and Dissertations

In search guided by meta-heuristics, a fundamental tradeoff exists between exploitation of good solutions (intensification) and exploration of the solution space for better solutions (diversification). Over-exploitation can limit the search to suboptimal solutions while over-exploration can reduce the efficiency of the overall search. Ant Colony Optimization (ACO) is a well-known meta-heuristic inspired by biological ants for solving NP-hard combinatorial search problems like the Traveling Salesman Problem (TSP). In nature, biological ant colonies navigate to find efficient paths around complex obstacles by depositing and following simple chemicals called pheromones. ACO algorithms model this behavior by implementing sets of artificial ants which …

Investigating The Structure Of Potential New Drug To Treat Sickle Cell Anemia Through Inhibition Of The Polymerization Of Hemoglobin S​, Brianna M. Lacasse, Isadora R. De Abreu, Rathika Manikandan

Protein Modeling Reports

Sickle cell anemia is a hematologic disorder impacting over 15 million people worldwide. It is caused by a single point mutation in the gene hemoglobin-Betha, where a glu group is replaced by val (GAG --- GTG) in the seventh codon (glu7val) of chromosome 1. In this study, we are comparing the anti-sickling properties of drugs in varied conditions in order to create a drug that is effective in an O2-independent manner and with a 1:1 stoichiometry for lower dosage purposes. We used Pymol and Jmol to compare the structures of the aldehydes GBT-440 and VZHE-039, which interact on the same …

Nsu College Of Pharmacy_Brochure_2021, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Winter 2021 Academic Calendar, Registrar Office

Academic Calendars of the NSU Registrar

No abstract provided.

Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.

Contribution Of The Human Microbiome And Proteus Mirabilis To Onset And Progression Of Rheumatoid Arthritis: Potential For Targeted Therapy, Jessica Kerpez, Marc Kesselman, Michelle Demory Beckler

Internet Journal of Allied Health Sciences and Practice

The human microbiome has been shown to play a role in the regulation of human health, behavior, and disease. Data suggests that microorganisms that co-evolved within humans have an enhanced ability to prevent the development of a large spectrum of immune-related disorders but may also lead to the onset of conditions when homeostasis is disrupted. In many conditions, a link between dysbiosis (microbial imbalance or microbiome upset) has been identified and associated with immune conditions such as rheumatoid arthritis (RA). This review provides insight into how an individual’s unique microbiome, combined with a genetic predisposition and environmental factors may lead …

Deep-Pelagic Research In The Gulf Of Mexico: Ten Years And Counting…, Tracey Sutton

Marine & Environmental Sciences Faculty Articles

No abstract provided.

Context-Responsive Equitable Strategies For Developing Gender-Responsive Curriculums In Nepal, Parbati Dhungana Ms, Roshani Rajbanshi, Lina Gurung

Transformations

We argue that context-responsive equitable strategies support the development of a gender-responsive curriculum in the context of higher education in Nepal. This paper is our reflective journey of curriculum content analysis of the two Master’s programs (Mathematics and English) from an inclusive cultural perspective of gender which engaged us to explore the answer to the question- How can we develop a gender-responsive curriculum? Adapting inclusive cultural perspective and participatory design we engaged with students and faculties and management representatives in the process of gender mainstreaming through action-reflection cycles. Further, we braided discussion with poetry, that is, a poetic inquiry to …

Pause For A Cybersecurity Cause: Assessing The Influence Of A Waiting Period On User Habituation In Mitigation Of Phishing Attacks, Amy Antonucci

CCAC Theses and Dissertations

Social engineering costs organizations billions of dollars a year. Social engineering exploits the weakest link of information security systems, the people who are using them. Phishing is a form of social engineering in which the perpetrator depends on the victim’s instinctual thinking towards an email designed to create a fear or excitement response. It is well-documented in literature that users continue to click on phishing emails costing them and their employers significant monetary resources and data loss. Training does not appear to mitigate the effects of phishing much; other solutions are necessary to mitigate phishing.

Kahneman introduced the concepts of …

Investigating The User Experience With A 3d Virtual Anatomy Application, Winnyanne Kunkle

CCAC Theses and Dissertations

Decreasing hours dedicated to teaching anatomy courses and declining use of human cadavers have spurred the need for innovative solutions in teaching anatomy in medical schools. Advancements in virtual reality (VR), 3D visualizations, computer graphics, and medical graphic images have enabled the development of highly interactive 3D virtual applications. Over recent years, variations of interactive systems on computer-mediated environments have been used as supplementary resource for learners. However, despite the growing sophistication of these resources for learning anatomy, studies show that students predominantly prefer traditional methods of learning and hands-on cadaver-based learning over computer-mediated platforms.

There is limited research on …

A Study Of Factors That Influence Symbol Selection On Augmentative And Alternative Communication Devices For Individuals With Autism Spectrum Disorder, William Todd Dauterman

CCAC Theses and Dissertations

According to the American Academy of Pediatrics (AAP), 1 in 59 children are diagnosed with Autism Spectrum Disorder (ASD) each year. Given the complexity of ASD and how it is manifested in individuals, the execution of proper interventions is difficult. One major area of concern is how individuals with ASD who have limited communication skills are taught to communicate using Augmentative and Alternative Communication devices (AAC). AACs are portable electronic devices that facilitate communication by using audibles, signs, gestures, and picture symbols. Traditionally, Speech-Language Pathologists (SLPs) are the primary facilitators of AAC devices and help establish the language individuals with …

Feature Selection On Permissions, Intents And Apis For Android Malware Detection, Fred Guyton

CCAC Theses and Dissertations

Malicious applications pose an enormous security threat to mobile computing devices. Currently 85% of all smartphones run Android, Google’s open-source operating system, making that platform the primary threat vector for malware attacks. Android is a platform that hosts roughly 99% of known malware to date, and is the focus of most research efforts in mobile malware detection due to its open source nature. One of the main tools used in this effort is supervised machine learning. While a decade of work has made a lot of progress in detection accuracy, there is an obstacle that each stream of research is …

Graduate Catalog And Student Handbook 2021-2022, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice Graduate Course Catalogs

No abstract provided.

Association Between Anthropometric Factors And Balance Among Elderly Fallers And Non-Fallers: A Cross-Sectional Study, Pothiraj Pitchai, Reshma Gurav, Srishti Kuldeep Chauhan

Internet Journal of Allied Health Sciences and Practice

Purpose: Falls are an emerging public health problem causing a cascade of medical, functional, and socio-economic consequences. Apart from other widely explored risk factors affecting balance, anthropometric factors are also known to have an impact on balance. However, this relationship hasn’t been studied extensively in older adults. This study aimed to evaluate the relationship between the anthropometric factors such as Body Mass Index (BMI), Body Fat Mass (BFM), Waist-Hip Ratio (WHR), Lower Limb Length (LLL), Foot Length (FL) and balance in the elderly among fallers and non-fallers. Method: This cross-sectional study was performed on 100 fallers and 100 non-fallers, aged …

2021-2022 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University

Halmos College of Arts and Sciences Course Catalogs

No abstract provided.