Digital Commons Network^™

Comparative Study Of Homocoupling Reactions To Create 2,2'-Bipyridine Adducts, Ethan Depry, Hoa Le

Undergraduate Student Symposium

The project focuses on investigating the synthesis of 2,2’-bipyridine adducts for potential use as ligands in novel organometallic ruthenium complexes. The bipyridine building blocks, based on their excellent bidentate ligands with complexing abilities, will be incorporated into ruthenium complexes in a collaborative project, increasing the photosensitivity of these complexes, and opening the doors for many applications, ranging from synthetic photovoltaics to anti-cancer activity.

The aim of this study was to optimize the preparation of the 2,2’-bipyridine adducts. Prior studies conducted in our lab have compared several homo and cross coupling reactions. It was determined that homocoupling offers a more efficient …

Deficits In Gait Biomechanics In Runners On A University Team: Implications For Preventative Sport Healthcare, W. Zachary Dean

Undergraduate Student Symposium

Sport healthcare providers in team-based settings conduct functional testing to identify injury risk. Results are used in team-based injury prevention programs. This process is different than care for a patient once they become injured. Gait analyses are a functional test for runners. Therefore, we aimed to describe the bilateral running biomechanics in a university cross country team with emphasis on variables linked to running-related injury (RRI). Twenty-seven male (n=10) and female (n=17) distance runners (age, 18-23yrs; height, 1.82±0.57m; mass, 58.4±6.8 kg) from a single university team participated in this descriptive study. Gait was assessed during a treadmill run at a …

Determinants Of Hospital Charges For Hospital Admissions And Readmissions In 2017 In The United States For Bronchitis And Asthma With Complications And Comorbidities (Drg = 202), Japjot Singh

Undergraduate Student Symposium

Understanding hospital charges in the U.S. healthcare system is vital for value-based care, recovery, and socio-economic wellbeing of the public. Hospital charges vary across hospitals regionally as well as nationally. As per the clinical history of hospital in-patient care, there are several determinants of hospital charges that are specific to the patient, disease, hospital, or the chargemaster. Empirical research on hospital in-patient care has bolstered the extant knowledge on the factors that determine the healthcare cost and utilization, but research is limited on how hospital readmissions impact hospital charges. The Agency for Healthcare Research and Quality (AHRQ) has developed a …

Effect Of Gamma Irradiation On Vitamin D Stability In Salmon, Varun Natarajan

Undergraduate Student Symposium

Salmon and other finfish are one of the major dietary sources of vitamin D. However, the presence of pathogenic bacteria, such as vibrio sp and listeria sp, can lead to foodborne illnesses. In 2015, 18% of foodborne illnesses were attributed to finfish. Gamma irradiation can serve as an effective tool to minimize bioburden and thereby decrease the risk of foodborne illnesses. While gamma irradiation has been used on other types of food, including chicken and crustaceans, its effects on fresh finfish has not been studied. This project examines the effect of low dose gamma irradiation on the stability of vitamin …

Effect Of Periodontitis On Inducing Late Onset Alzheimer's Disease (Load) Pathology In Mice, Neha Gupta, Courtney Mai, Miguel Cuello

Undergraduate Student Symposium

Alzheimer’s disease is the most common form of dementia; affecting approximately 50 million people worldwide. Recent evidence indicates poor dental hygiene may accelerate Alzheimer’s degeneration. Experimenters used a mouse model of periodontitis induced by P. gingivalis and investigated the implications of poor dental health on Alzheimer’s Disease and neuroinflammation, as well as memory skills, in relation to aging, gender, and condition. All the mice in the model were the same age, and a total of 8 mice with Alzheimer’s Disease and 8 mice who had Alzheimer’s Disease with inflammation with an equivalent number of males and females were utilized. Experimenters …

Effect Of β-Lactamase Expression And Varying Metabolism On The Inoculum Effect, Kielan Singh, Vijay Patel

Undergraduate Student Symposium

Infections with antibiotic resistant bacteria pose a substantial challenge to the field of medicine. Accordingly, it is of the utmost importance that we understand the mechanisms by which bacteria resist antibiotics towards the development of novel drugs and treatment paradigms. One mechanism by which a population of bacteria can resist an antibiotic is the inoculum effect (IE). During IE, the initial density of the population determines the efficacy of the antibiotic; highly dense populations of bacteria require more antibiotics to kill the population as compared to less dense populations. One mechanism that has been proposed to explain IE is the …

Effects Of Water Hyacinth Management On Fish Populations, Sara Schutt, Mary Hill, Melanie Vasquez

Undergraduate Student Symposium

Invasive water hyacinth (Eichhornia crassipes) creates significant economic and ecological problems in Florida. Removal of this invader cost an estimated $4.19 million in the 2020 fiscal year. Water hyacinth has also been shown to alter water quality and chemistry and reduce fish populations. Current management strategies involve manual removal and the application of herbicide. New methods, including biological control, are being investigated to improve the efficiency of current management methods. Questions about the effects of these novel management strategies have emerged, including the response of fish populations to the new treatments. To answer these questions, we set up …

Emotional Resilience Of The Covid-19 Pandemic On A College Campus, Jenna Binaco

Undergraduate Student Symposium

The perceptions of people during the Covid-19 pandemic cannot always be true. This is due to a life of uncertainty and for many people, fear. Since the pandemic has been around for about two years, this is an excellent opportunity to see how this pandemic has impacted people’s mental health. A way that this information can be recorded is with The Emotional Resilience scale of the Covid-19 Pandemic on a College Campus. Emotional resilience was measured in 1704 American university students, staff, and faculty in October to November 2021 of the Covid-19 pandemic. This was a transitional period for people …

Endoparasite Community Of Common Wood-Warblers (Family Parulidae) In Southeast Florida, Skylar Olsen

Undergraduate Student Symposium

Wood-warblers are small insectivorous passerine birds in the family Parulidae. They are among the first migratory birds in North America to begin their southward migration during the early autumn months and southeast Florida serves as a wintering ground. Although wood-warblers are common and widespread, knowledge of their endoparasite community composition is severely underrepresented in current literature. Carcasses were opportunistically collected from wildlife rescue centers in southeast Florida. The digestive tract of 90 birds representing 5 common wood-warbler species were examined for endoparasites: Common Yellowthroats (Geothlypis trichas), Ovenbirds (Seiurus aurocapilla), Black-and--White Warblers (Mniotilta varia), Palm Warblers (Setophaga palmarum), and American Redstarts …

Examining The Impact Of Mind Wandering On Task Performance: Does Task Difficulty Matter?, Kortne Bajor, Jozef Cruz, Amulya Chowd Koritala, Gargee Pandya

Undergraduate Student Symposium

Mind wandering is a phenomenon in which an individual’s thoughts drift from the current task to a task unrelated thought (TUT). It is known to be affected by various factors such as state of mind, neuroticism, and boredom which may differ for each individual. Task difficulty appears to impact mind wandering rates, such that mind wandering increases on tasks with lower difficulty (Seli et al., 2018). However, prior work has not examined how emotionally valenced mind wandering impact task performance at different levels of task difficulty. Mind wandering typically predicts poorer ongoing task performance (McVay & Kane, 2010) and negatively …

Exploring The Prevalence Of Carpal Tunnel Syndrome (Cts) Symptoms In College Students, Kyrah Maduro

Undergraduate Student Symposium

Carpal tunnel syndrome (CTS) causes functional impairments and is prevalent in occupations involving repetitive hand movements. Given the extensive use of electronic devices for coursework, college students may be at risk for CTS. The purpose of this study was twofold: to examine the symptomology of CTS in college students, and to determine treatment strategies used by occupational therapists (OT) who treat college students with CTS. We developed and administered a 17-question College Student CTS Experiences Survey for students. Participants were recruited via flyers posted on a university campus. Inclusion criteria for responding included being a college student experiencing pain, tingling, …

Firearm-Related Injuries Rates From 2014 To 2017 Among Floridian Children, Joel Marlapudi

Undergraduate Student Symposium

Purpose: To assess the prevalence of firearm-related injuries among pediatric patients in Florida by age, race, and ethnicity.

Method: The dataset from the Florida’s Agency for Health Care Administration from 2014-2017 was utilized for this analysis as well as the Florida Community Health Assessment and Resource Tool Set. The study included ambulatory ED-visits of Floridian patients (aged ≤ 19 years) who had firearm-related Principal Diagnosis coded using the International Classification of Diseases. Patients who reported race as White or Black and Ethnicity as Hispanic or non-Hispanics were included. Patients’ county was categorized into 11 regions defined by Florida Local Health …

Gadra's Allegory, Bianca Vucetich

Undergraduate Student Symposium

“Gadra’s Allegory” is a silent (with no dialogue, but music is utilized) short film that follows a modern day ‘prisoner’ who exemplifies how their society is chained to the screens that surrounds them. The film shows their journey from a repetitive, thoughtless, and disillusioned way of life, to a majestic awakening to the nature of reality. This film is based on and inspired by Plato’s “Allegory of the Cave,”; though the main character of the film is based off the chained prisoner of the allegory, this alternate version shows another path to their own enlightenment and expresses their own internal …

Great Plains Midcontinental Loess Deposits Following Prehistoric Megadroughts And Climate-Change Related Ecosystem Collapse In The Badlands, Melanie Vasquez, Drew Tozer, Catherine Acosta

Undergraduate Student Symposium

Understanding effects of prehistoric extreme climate events on the environment is necessary to help predict effects of modern global climate change. Research shows prehistoric megadroughts caused the collapse of North American grassland ecosystems, allowing wind to erode soils and fined-grained sediment. Timing, severity, and regional extent of these megadroughts remain controversial, but research indicates at least three megadrought periods on the North American midcontinent over the last 20,000 years. Evidence for prehistoric megadroughts is preserved in dune fields and loess deposits throughout the North American Great Plains, including our field area in the Badlands of South Dakota. Loess, composed of …

Ha Ha Ha... Good One!... Not You Hmongs. Laughter, White Privilege, And "Othering" In Medical Cultures, Sarah Soliman

Undergraduate Student Symposium

The response to alternative medical approaches of underprivileged and underrepresented groups detailed by Anne Fadiman differ from the hegemonic alternative approaches exemplified by Norman Cousins. In The Spirit Catches You and You Fall Down, Fadiman describes the inadequate efforts made by healthcare professionals to communicate with the Lee family who did not understand English and had significantly different medicinal practices from Western biomedical practices. Rather than being met with respect and attentiveness, these medical professionals viewed this family as “difficult” and “stupid.” In comparison to the various mistreated groups of minorities, the Hmong are a minority within the minority …

Heavy Metal Contaminants In The Sciaenids From Lake Sabine, Katerina Sawickij

Undergraduate Student Symposium

Lake Sabine is a shallow, estuarine lake situated on the border between Texas and Louisiana with outflow to the Gulf of Mexico. The Louisiana side is a protected natural area while the Texas side is susceptible to pollution from several commercial industries as well as maintenance dredging. This study determined the concentrations of metal(loids) within commercially and economically important fish tissues and compared them intra- and inter-specifically using known diets and a range of sizes. Specimens were collected from Lake Sabine from April through October 2018 from four sciaenid fishes: Atlantic Croaker Micropogonias undulatus, Red Drum Sciaenops ocellatus, …

Human Mtdna Copy Number Quantification, Leonardo Lacayo, Luzcarime Saco-Vertiz

Undergraduate Student Symposium

Our social worlds and physical health are profoundly intertwined, but we have limited tools for studying these important connections. Within the recent psychiatric literature, changes in mitochondrial DNA copy number (mtDNAcn) have been linked to a variety of socially influenced mental illnesses such as major depression. In principle, this biomarker may therefore also be responsive to more subtle changes in our social environments, including life events that attenuate stress.

This poster outlines plans for a novel molecular study of how interspecies social bonding impacts human cells. Specifically, we propose to use quantitative PCR to measure the abundances of (single copy) …

I Can Hear You, I Just Can't Remember You: Deconstructing The Sensory And Cognitive Components Of Hearing Loss, Pranay Narang, Hana Amireh

Undergraduate Student Symposium

Hearing loss is commonly thought of as solely a sensory, not cognitive, problem. According to the effortfulness effect, however, those with presbycusis are burdened with an increased attentional cost for auditory processing, taxing the central executive such that working memory is impaired. The excess strain placed on the central executive to decode sensory noise ultimately impairs one’s capacity to attend to and consolidate memories, compromising retention. We hypothesize that the presence of white noise during encoding will mimic the effect of hearing loss sustained in older adults and will impair the retrieval of auditory information in those with normal hearing. …

Implications Of Covid-19 For Education And Research In Healthcare And Stem: Analysis Of Global Case Studies, Yumna Indorewala

Undergraduate Student Symposium

The novel coronavirus, SARS-CoV-2 has posed a major threat to global education and research in STEM and healthcare. Social distancing guidelines were initially recommended to refrain from face-to-face operations for preventing the transmission of the virus. As schools and higher academic institutions implemented multifarious methods to effectively transition to remote/online or hybrid educational formats, the Coronavirus Infectious Disease 2019 (COVID-19) pandemic introduced further hurdles and necessitated designing, adopting, as well as evaluating the efficacy of new instructional approaches, especially for disciplines that require active, experiential learning such as healthcare and STEM. These effects are accentuated in less developed/developing nations or …

Induction Of Necroptosis In Mcf-7 Breast Cancer Cells Through Caspase-Independent Mechanisms Following Saha Treatment, Grace Waldron

Undergraduate Student Symposium

Currently, many anti-cancer drugs are known to induce programmed cell death (apoptosis) through activation of intrinsic or extrinsic pathways. However, many types of cancer cells have acquired resistance to apoptosis-mediated cell death. Therefore, simultaneous induction of other forms of cell death in addition to apoptosis of cancer cells is becoming an attractive strategy. For this purpose, we initially explored the role of XIAP in caspase-dependent and caspase-independent mechanisms of cell death. Our western blot data revealed that RIPK3 and MLKL levels were significantly elevated in MCF-7 cells following SAHA treatment. During induction of SAHA-induced cell death, the XIAP levels were …

Inter-Limb Kinetic Asymmetries Differ Between Concentric And Eccentric Phases Of The Vertical Jump, Vanessa Alexandre

Undergraduate Student Symposium

Inter-limb asymmetries during the vertical jump (VJ) have been used to identify injury risk and performance deficits with >10% being a threshold. Force, or kinetic asymmetries have typically been studied for the concentric (propulsive) phase of the VJ while eccentric (loading) phase analyses are limited. The purpose of this study was to determine if there were differences in inter-limb asymmetry (%) in impulse (force * time) and peak force between VJ eccentric and concentric phases. Results may inform coaches and sport healthcare providers. Participants were 60 highly skilled males (age, 22.7±1.1yrs.; height, 186.4±6.8cm; mass, 103±21.2kg) undergoing training for the National …

Investigating The Bouba-Kiki Phenomenon In Impression Formation, Pritika Shah

Undergraduate Student Symposium

Humans associate sounds and symbols in non-arbitrary ways. One example of this phenomenon is the Bouba/Kiki effect: the nonword “Bouba” is associated with rounder shapes, whereas “Kiki” is associated with sharper shapes. Although many studies have been done on the Bouba-Kiki effect, it has not been studied in the context of personality judgments and impression formation. Study 1 used a between-subjects design to test the Bouba/Kiki effect in this domain. A person named “Bouba” was rated as more moral than a person named “Kiki”, whereas “Kiki” was rated as more sociable, however no significant difference was found for competence ratings. …

Investigating The Specific Phosphorylation Sites Of The Human Mineralocorticoid Receptor Using Phospho-Mapping, Valentina Guidi

Undergraduate Student Symposium

The purpose of this project is to confirm the specific sites where G protein receptor kinase 5 (GRK-5)- mediated phosphorylation of the mineralocorticoid receptor (MR) of aldosterone occurs. The significance of the study stems from prior findings indicating that e-cigarette vapors induce lung inflammation and tissue destruction. While research has typically focused on the effects of tobacco use, the detrimental influence of e-cigarette vapors, which accumulate in the airway epithelium, must also be identified. This may include desensitization of the beta2-adrenergic receptor (β2AR), a protective receptor against airway inflammation and fibrosis and the only AR subtype expressed in human bronchial …

Measuring The Effect Of Methionine Deprivation In Genome Methylation Of Ccp Genes Within The Prolaris Molecular Score Along Prostate Cancer Cell Lines, Yatin Srinivash Ramesh Babu, Trevor Fuhriman Oms 2, Andy Aleman Espino Oms 2

Undergraduate Student Symposium

Impairment of physiological metabolism is the trademark of various cancers and cancer cells as a component of their mechanism which ultimately bolsters survival. While normal cells are highly regulated and follow a sophisticated mechanism of cellular metabolism to achieve their goals of survival, cancer cells take the dysregulated path for survival, ultimately robbing the overall vital energies of the entire organism. Unfortunately, only a limited number of uniform ways exist that permit for a complete cure of various presentations of cancers. The PC3 cell line has been reported to be dependent upon exogenous pools of methionine, whereas the DU-145 cell …

Minimal K-Blockers Of 123-Avoiding Permutation Matrices, Megan Bennett

Undergraduate Student Symposium

We investigate n × n (0, 1)-matrices A that avoid σk, where σk is the permutation {1, 2,…, k}, and we focus on 123-avoiding permutations. A k-blocker of 123-avoiding permutation matrices is a set of positions in an n × n matrix that intersect each 123-avoiding permutation matrix at least k times. The Hankel cyclic decomposition implies that each k-blockers must have cardinality at least kn. The dimensions of the k-blockers of all permutation matrices are determined by Fulkerson’s generalization of the Frobenius-König theorem: any r × s submatrix is a k-blocker of all permutation matrices if r …

Phage Hunters: The Discovery Of Two Novel Bacteriophages That Infect Gordonia Rubripertincta, Sarah Ballarin, Neel G. Balusa, Melissa Bell, Samia Caballero, Joshua Chan, Maria P. Farez, Ashley Guillen-Tapia, Nashrah Pierre-Louis, Victoria Polishuk, Bhavya Soni

Undergraduate Student Symposium

Antibiotic resistance is a global healthcare concern because it poses a threat to effectively treating bacterial infections and the need for alternative therapeutics are urgently required. Phage therapy, which uses viruses to treat bacterial infections, is a promising alternative to conventional antibiotics. Phages have also been widely used in the food industry to prevent microbial growth on certain foods and are currently being explored as a method for bioremediation of oil spills and wastewater treatment. Although phages are ubiquitous in nature, many have yet to be discovered. Through the SEA-PHAGES (Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science) program …

Physiological Mechanisms Of Pregnancy: How The Kidneys And The Renin-Angiotensin System Protect The Fetus, Raghavi Vuppala, Crystal West

Undergraduate Student Symposium

Physiological changes concurrent with pregnancy include plasma volume expansion with increased sodium retention to enable normal development of the fetus. Expansion of plasma volume and sodium reabsorption are adaptive mechanisms that occur in response to the altered physiological state of pregnancy. These adaptations are mediated by the renin-angiotensin system (RAS) and its primary hormone, angiotensin (Ang) II, acting on the kidney. The role of Ang II in the kidney also involves stimulation of aldosterone release from the adrenal gland, which promotes sodium retention by the kidney. Ang II activates its two main receptors in the kidneys: AT1 and AT2. The …

Raising Awareness About Recognizing Pediatric Obstructive Sleep Apnea Associated With Down Syndrome: Developing A Health Education Program, Mahima Dave

Undergraduate Student Symposium

Down syndrome (DS) is the most prevalent chromosomal disorder in which an extra copy of chromosome-21 disrupts the development of intellectual abilities. Unique physical manifestations places children with DS at high risk for obstructive sleep apnea (OSA) in which repeated blockages of the upper airway cause difficulty breathing during sleep. 80% of children with DS are afflicted with OSA compared to only 2-5% of the general pediatric population. OSA increases incidences of nocturnal sudden cardiac arrest by 2.57-fold compared to the general population. Common signs of OSA include snoring, restlessness during sleep, night waking, and daytime tiredness. Manifestations of OSA, …

Re-Discovery Of Microatolls In The Galapagos Islands, Ecuador, Amber Orr

Undergraduate Student Symposium

Microatolls are coral colonies with a signature ring-like shape. They form in shallow water where depth limits vertical growth, allowing them to be utilized as indicators of current and past sea level. Additional contributors to their formation include accumulation of sediment on the colonies which smothers corallites in the center of the structure, overgrowth by algae, and upper surface abrasion by bioeroding organisms. Microatolls occur at numerous locations in the Indo-West Pacific, however, they are reported at only two known locations in the tropical eastern Pacific: Caño Island, Costa Rica and the Galápagos Islands, Ecuador. More than 50 Porites lobata …

Skill Football Players Outperform And "Outforce" Big-Skill And Big Players In The Vertical Jump, Jeffrey Marin, Erica Vazquez

Undergraduate Student Symposium

Vertical jump (VJ) performance is critical for football players. Position demands vary and may influence VJ loading (eccentric) and propulsion (concentric) forces. Examining forces in addition to jump height (JH) informs training programs. We aimed to determine differences in VJ performance [reactive strength (RSImod, m/s); JH (cm)] and peack concentric (CON-PF) and eccentric (ECC-PF) forces between position groups. Sixty football players (age, 22.6±1.1yrs; ht, 186.4±6.8cm; mass, 103.6±21.2kg) representing three position groups, Skill, Big-Skill, and Big, performed VJ on dual uniaxial force plates. ForceDecks software allowed for calculation of the dependent variables. ECC-PF and CON-PF were normalized to body mass (N/kg). …