The Effects Of Early Exposure To Prescription/Illicit Drugs And Drug Metabolites On Larval Zebrafish Behavioral And Motor Function Development, Jacob Thomas, Dena Weinberger, Bikram Subedi, Brandon Capps

Murray State Theses and Dissertations

THE EFFECTS OF EARLY EXPOSURE TO PRESCRIPTION/ILLICIT DRUGS AND DRUG METABOLITES ON LARVAL ZEBRAFISH BEHAVIORAL AND MOTOR FUNCTION DEVELOPMENT

A Thesis Presented to the Faculty of the Department of Biology

Murray State University

Murray, Kentucky

In Partial Fulfillment of the Requirements for the Degree of Masters In Science

By Jacob Thomas, B.S., Murray State University

December 2024

Acknowledgements

Brandon Capps, who pretty much did a whole third of the legwork on this project and saved me lots of headaches;

Chandler Maddox, one of the University of Kentucky’s finest undergrads who came in from the top rope with a folding chair …

Perceptions Of Benefits From Middle School Agricultural Education Programs, Michael Hunter

Murray State Theses and Dissertations

As agriculture education continues to evolve across the state of Georgia and the country, leaders need to understand the dynamic vision and the importance of this industry. Utilizing P-20 education initiatives and new concepts, leaders can implement agriculture education in more schools to increase diversity and provide students with opportunities to participate in the three-component model of agriculture education. This research aimed to explore the perceived benefits that high school principals, CTAE directors, and agriculture teachers have on middle school agriculture education programs. This research was confined to the Georgia FFA North Region. Findings indicated no significant evidence that middle …

2023-12-08, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Orca Annual Report 2022-23, Msu Orca

Steeplechase: An ORCA Student Journal

Quick Facts about ORCA, AY 22-23

• 12 of 12 slots filled for Posters-at-the-Capitol with projects from the College of Business, the College of Humanities and Fine Arts, the School of Agriculture, and the College of Science, Engineering & Technology
• 350 students presented in both Scholars Weeks with support from 88 individual faculty members
• 20 grants awarded totaling over $15,000
• 17 items published in Steeplechase: An ORCA Student Journal

5th Annual Occupational Therapy Program Research Conference, Kelly L. Taylor Ms, Otr/L, Cbis

Student Scholarship & Creative Works

Occupational Therapy Program RESEARCH CONFERENCE

5TH OT COHORT | CLASS OF 2024

OT Program Student Presentations Graduate Students from the Class of 2024

Phenotypic Plasticity Of Male Calls In Two Populations Of The Katydid Neoconocephalus Triops (Insecta: Tettigoniidae), Oliver M. Beckers, Teiya Kijimoto, Johannes Schul

Faculty & Staff Research and Creative Activity

The ability to respond to environmental changes plays a crucial role for coping with environmental stressors related to climate change. Substantial changes in environmental conditions can overcome developmental homeostasis, exposing cryptic genetic variation. The katydid Neoconocephalus triops is a tropical species that extended its range to the more seasonal environment of North America where it has two reproductive generations per year. The harsher winter conditions required adults to diapause which resulted in substantially different mating calls of the diapausing winter animals compared to the non-overwintering summer animals in northern Florida. The summer call corresponds to that of tropical populations, whereas …

Poly(Propylene Glycol)-Based Non-Isocyanate Polyurethane Ionenes: Thermal, Morphological And Conductive Properties, Jordan C. Pierce, George M. Timmermann, Creston Singer, David Salas-De La Cruz, Kevin Miller

Faculty & Staff Research and Creative Activity

The synthesis and characterization of a series of polyurethane ionenes using a non-isocyanate approach is disclosed. Imidazole-capped, urethane-containing prepolymers are prepared by first reacting carbonyl diimidazole (CDI) with several poly(propylene glycol) (PPG) diols with variable molecular weight, followed by subsequent reaction with 3-aminopropylimidazole (API). Polymerization with 1,4-dibromomethylbenzene followed by anion exchange resulted in the desired polyurethane ionenes bearing the [NTf2] counteranion as a series of viscous liquids. NMR and FTIR spectroscopy are used to characterize the intermediates and final ionenes, including molecular weight determination by end-group analysis. A single glass transition temperature (Tg), as determined by differential scanning …

Multi-Species Host Use By The Parasitoid Fly Ormia Lineifrons, Kyle J. Rogers, Oliver M. Beckers

Faculty & Staff Research and Creative Activity

Antagonistic species relationships such as parasitoid/host interactions lead to evolutionary arms races between species. Many parasitoids use more than one host species, requiring the parasitoid to adapt to multiple hosts, sometimes being the leader or the follower in the evolutionary back-and-forth between species. Thus, multi-species interactions are dynamic and show temporary evolutionary outcomes at a given point in time. We investigated the interactions of the multivoltine parasitoid fly Ormia lineifrons that uses different katydid hosts for each of its fly generations sequentially over time. We hypothesized that this fly is adapted to utilizing all hosts equally well for the population …

2023-08-25, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

2023-06-02, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Determination And Comparison Of Freely Dissolved Pahs Using Different Types Of Passive Samplers In Freshwater, Na Yeong Kim, Bommanna G. Loganathan, Gi Beum Kim

Faculty & Staff Research and Creative Activity

Polycyclic aromatic hydrocarbons (PAHs) are well-known for their recalcitrant properties and biotoxicity in organisms, leading to serious environmental and health problems. Despite various analytical methods available, accurate determination of the bioavailable fraction is warranted in order to evaluate the precise toxic potentials of these compounds. Currently, the passive sampler is used worldwide to measure the bioavailable PAHs in the environment using the equilibrium partitioning principle. In this study, we co-deployed different types of passive samplers, which are linear low-density polyethylene (LLDPE) and low-density polyethylene (LDPE), to determine freely dissolved concentrations (Cfree) of PAHs using the performance reference compounds (PRCs) in …

Designing The Power System Of A Robot, Nolan Hays

Honors College Theses

This thesis outlines the acquired skills and knowledge acquired through the course of four years of Murray State University’s School of Engineering. The capstone for students in the department was to team up and complete an interdisciplinary senior design project using skills from various tracks of engineering. For this thesis, there is a greater emphasis on the electrical engineering track. The objective of the project was to build an autonomous robot to complete the various tasks within the scope of the IEEE SoutheastCon 2023 Hardware Competition. The robot was controlled via a Raspberry Pi 4 Model B. There were three …

Sensor Updates For Bigheaded Carp-Tracking Autonomous Boat, Jordan Kaufmann

Honors College Theses

Bigheaded carp are an invasive species that overpopulate and compete with the native species of Kentucky Lake as well as many other North American aquatic ecosystems. The movement patterns of Bigheaded carp are being studied nationwide by the United States Geological Survey and multiple universities. These studies ultimately seek to control their spread and reduce or reverse the ecosystem destabilization caused by this invasive species. Such studies are currently conducted manually on Kentucky Lake by graduate students affiliated with the Murray State University (MSU) Biology Department and Hancock Biological Station, and these manual studies are an arduous and time-consuming effort. …

A Review Of The Causes Of Optic Nerve Atrophy And Potential Ways Of Axon Regeneration In The Optic Nerve, Cole Wyatt

Honors College Theses

The optic nerve connects the eye to the lateral geniculate nucleus in the brain and is a key component in the human visual pathway. The optic nerve is made up of the axons of approximately 770,000 to 1.2 million specialized neurons called retinal ganglion cells. Like any other organ and tissue in the body, the optic nerve is susceptible to damage or injury. However, unlike some other organs and tissues, once damaged, the optic nerve cannot regenerate. Individuals with damaged optic nerves are said to have Optic Nerve Atrophy and, as of now, there are no cures or treatment options …

Gauging Clientele Knowledge On Alternative Methods Of Payment For Veterinary Services In Relation To Client Satisfaction, Olivia Hritzkowin

Honors College Theses

The following study focuses on the knowledge that veterinary clients possess surrounding alternative methods of payment for veterinary services and its relation to overall client satisfaction, as well as the prevalence of mental health crisis in veterinary professionals as it relates to client satisfaction. An in-depth analysis of online articles and journals was compared to the results of a survey of pet owners and veterinary professionals to obtain results for the study. The results of the analysis of online resources revealed that many pet owners are stressed about paying for veterinary care for their animal and that most are unprepared …

Sex And Environmental Effects On Chemical Signals Of Gryllus Rubens, Marion Davis Creech Iii, Marion Davis Creech Iii

Honors College Theses

Many animals communicate with one another in the context of reproduction, utilizing different modalities. In some cases, more than one modality is used by the sender and receiver. Each modality can provide different sets of information, or function in a different context. Importantly, no matter the modality, the signals should be clearly distinguishable between males and females and need to be reliable even in the face of environmental changes.

In field crickets, there are two major modes of communication. For long-range communication, the males produce acoustic signals to attract females. At short-range, chemical communication involving cuticular hydrocarbons (CHCs) in males …

Free-Body Diagram Analysis And Movement Design Of A Functional Prosthetic Hand, Hayden Smee

Honors College Theses

The loss of a limb is a devastating event to an individual on both physical and psychological levels. Despite decades of advancements in medicine, occupational health, and general safety in society, most people know someone or have encountered individuals affected by limb loss. This project created a prosthetic hand designed to aid those individuals. The hand is a predominantly 3D-printed prosthetic hand that includes an individually moving index finger and opposable thumb capable of grasping a full soda can weighing 385 grams (0.85 pounds). Numerous design solutions for the actuation of the fingers and thumb were considered and rejected. Cable …

A Probabilistic Exploration Of Food Supplementation And Assistance, Logan Mattingly

Honors College Theses

Food insecurity is a stark threat that grips our country and affects households throughout our country. Dietary insufficiency manifests itself in ways that affect health and public safety. According to researchers, individuals who suffer from food insecurity have a higher risk of aggression, anxiety, suicide ideation and depression. These problems tend to occur unequally distributed among those households with lower income. In this work, an exploratory analysis within these data sets will be performed to examine the socio-economic, biographical, nutritional, and geographical principal components of food insecurity among survey participants and how the US Supplemental Nutrition Assistance Program (SNAP) effects …

Programming An Autonomous Robot, Maxwell Brueggeman

Honors College Theses

Ravaged by hurricanes, Florida needed help restoring its natural beauty and returning its wildlife to their homes. This was the task for the IEEE SoutheastCon 2023 Hardware Competition. Florida’s restoration was simulated by returning various ducks and pillars that lay strewn across a game board to their proper places. Ducks needed to return to their pond, pillars needed to be stacked to create statues, and food needed to be placed in the manatee and alligator aquariums. Competing teams were challenged to create an autonomous robot capable of performing these tasks. During the first semester, sensor selection was tackled. Research was …

Review Of Biomedical Applications Of Cardiovascular Tissue Engineering, Natalie M. Howard

Honors College Theses

Tissue engineering can be defined as processes that aim to generate three-dimensional functional tissues in vitrothat have been favorably altered according to the structural, biochemical, electrophysiological, and biomechanical properties of the desired tissue before implantation into the human body. In relation to cardiac tissues, these properties would include the ability to conduct action potentials, withstand systolic pressure, permit sufficient O₂ and CO₂penetration, sufficient vascularization to supply nutrients for cellular activity, surface topology that enables cellular communication, and more. As heart diseases and instances of myocardial infarction continue to rise worldwide, there is an increasing need for …

Reconciling Occupational Safety And Health (Osh) Master's Of Science Curricula With Employer Demands, David W. Wilbanks Ph.D., Csp, Arm, Yousif Abulhassan Ph.D., Csp, Cpe, Jan K. Wachter Sc.D., Mba, Csp, Cih

Faculty & Staff Research and Creative Activity

This study concurrently investigated the characteristics of 20 distance learning United States OSH M.S. programs and 101 OSH employment postings preferring or requiring candidates with an advanced degree. The goal was to determine if there was consensus in the required curricula and employer demands. Such agreement is one of the requirements for achieving occupational closure, an important step for OSH being considered a profession. The results demonstrated there is both diversity in OSH M.S. courses being offered and in knowledge, skills, and abilities being sought by employers. A Pareto comparison analysis illustrated that more OSH M.S. programs should …

Structure And Movement Design To Build A Functional Prosthetic Hand, John Campbell

Honors College Theses

This project aims to create a functional prosthetic hand that will improve upon the previous design for this project. The previous design included four fingers which were moved using a four-bar linkage and slider crank mechanism in combination with a linear actuator to move all four fingers in unison. Two servo motors were used to create an opposable thumb that could be used to grasp objects. Movement of the prosthetic hand was activated using a signal received from a myoelectric sensor. The goal of this project is to study this design and attempt to upgrade the prosthetic hand utilizing a …

Making The Political Personal: Consciousness Raising For The Contemporary Trans Exclusionary Radical Feminist, Danica Fuerst

Honors College Theses

Consciousness raising (CR) typically refers to the specific small group practice pioneered by second-wave feminists, but as networked media gradually replaced the small group process, new forms that are descended from the original CR emerged. This thesis traces consciousness raising from it's origins in the late 1960s and early '70s, through third-wave feminism, to contemporary feminist uses. It analyzes the rhetorical effects and functions of CR from the perspective of Symbolic Convergence theory, considering the various media through which CR is practiced. Finally, using the understanding of CR and its functions that this provides, it analyzes how one specific contemporary …

Poly(Ether Imide)S: Synthesis And Properties, Rachel Price

Honors College Theses

The synthesis of strong polymers is crucial to the creation of heat-resistant, durable, and mechanically useful plastics that we use every day. Poly(ether imide)s are used in applications such as food service, aerospace, automotive, and many more. This thesis will discuss the synthesis and properties of these plastics to help express a larger understanding of these polymers.

Analysis And Methodology Of Helical And Flexible Homopolymer Monte Carlo Simulations, Nathan Roberts

Honors College Theses

The purpose of my work is to analyze the results of Monte Carlo simulations of various types of polymers: a helical homopolymer and a flexible homopolymer. Specific applications of Monte Carlo polymer simulations and parallel tempering replica exchanges are presented. Using temporal analysis, I aim to measure the efficiency of each type of simulation as it relates to equilibration time. For the helical homopolymer model, equilibration time is expanded upon to analyze the rate of structure generation and relevant hyper-phase diagram. Stable states for helical homopolymers will use data generated from parallel tempering replica exchange Monte Carlo simulations created by …

Analyzing Post-Fledging Movements, Survival, And Space Use Of First-Year Black Vultures (Coragyps Atratus) In Kentucky, Philip Kavouriaris, Andrea Darracq

Steeplechase: An ORCA Student Journal

The time span between a fledgling’s first flight from the nest and dispersal from its natal area is known as the post-fledging dependence period. This period is a critical life stage because it affects an individual’s survival and recruitment into adult populations. In Black Vultures, young birds learn to navigate their environment but remain dependent on their parents for food during this prolonged period. We analyzed movement data from nine fledglings equipped with backpack-mounted solar-powered transmitters (GPS/GSM 20-70 PTT, 45g, Microwave Telemetry, Inc.), which included over 450,000 locations collected over a period of approximately 250 days. Home range sizes and …

One-Dimensional And Two-Dimensional Simulations Of Helical Homopolymers: A Comparative Analysis Of Energy Stabilization And Efficiency, Matthew Hooks, Nathan Roberts, Matthew Williams Ph. D.

Steeplechase: An ORCA Student Journal

The purpose of our work is to analyze the results of a two-dimensional parallel tempering simulation of a coarse-grained helical homopolymer. We aim to measure the efficiency of the simulation and apply this efficiency to the theoretical protein free energy landscape.The stable states for helical homopolymers will be analyzed using the folding funnel theory of free energy landscapes for given polymer configurations. The genesis of each simulation is defined by a randomly configured polymer; as time progresses, the energy of each structure decreases until equilibrium is reached. Data collected after equilibrium is reached is used to understand polymer behavior for …

Synthesis And Characterization Of Semi-Interpenetrating And Double Networks Of Sulfonimide- And Imidazolium-Containing Poly(Ionic Liquids), Jeremiah Coughlon, Seth Taylor, Jason Bara, Kevin Miller, Sourav Chatterjee

Scholars Week

In recent years, there has been increased research interest in creating electrically conductive polymer membranes with materials that are widely available and environmentally safe. Herein, we report how polymeric membranes comprised of unique combinations of ionenes and poly(ionic liquids), including a recently developed sulfonimide- and imidazolium-containing methacryloxy-based monomer, were produced via UV photopolymerization. These membranes were specifically tailored to exhibit both ionic conductivity and an affinity for carbon dioxide, which are both crucial characteristics in such applications as electron transport in lithium-ion batteries and gas sorbency in separation techniques. Monomers, such as the aforementioned methacryloxy-based ionic liquid (IL) and C4VIm, …

Synthesis And Properties Of Bio-Based 3d Printable Resins, Cameron Woods, Seth Taylor, Jeremiah Coughlon, Turner Perdue, Sourav Chatterjee, Jason E. Bara

Scholars Week

A photopolymer resin is a monomer that, when introduced to light of a certain wavelength, starts to polymerize into a solid. This has become a growing part of the 3D printing industry. There have been many advancements in the field of 3D printing, however, a lot of these resins are not environmentally friendly and even harmful if not handled in the correct manner. Plant based resins are becoming more and more popular because of their biodegradability and for the possibility of using renewable resources. Glycerol is a plant-based compound that is produced in excess in industry. Glycerol obtained from bioethanol …

One-Dimensional And Two-Dimensional Simulations Of Helical Homopolymers: A Comparative Analysis Of Energy Stabilization And Efficiency​, Nathan Roberts, Matthew Hooks

Scholars Week

The purpose of our work is to analyze the results of a two-dimensional parallel tempering Monte Carlo simulation of a coarse-grained helical homopolymer. The two-dimensional simulation allows Hamiltonian exchanges across both temperature and torsion values, while the one-dimensional simulation exclusively exchanges across temperature values. The genesis of each simulation is defined by a randomly configured polymer; as time progresses, randomly generated movements of monomers decrease the structure’s energy until equilibrium is reached. Equilibrium is determined by finding the absolute minimum of the data series, computing the mean of all remaining data, and finding the intersection between the rolling average and …