Digital Commons Network^™

Targeting Orphan G Protein-Coupled Receptors For The Treatment Of Diabetes And Its Complications: C-Peptide And Gpr146, G. R. Kolar, S. M. Grote, G. L.C. Yosten

Biological Sciences Faculty Research & Creative Works

G protein-coupled receptors (GPCRs) are the most abundant receptor family encoded by the human genome and are the targets of a high percentage of drugs currently in use or in clinical trials for the treatment of diseases such as diabetes and its associated complications. Thus, orphan GPCRs, for which the ligand is unknown, represent an important untapped source of therapeutic potential for the treatment of many diseases. We have identified the previously orphan GPCR, GPR146, as the putative receptor of proinsulin C-peptide, which may prove to be an effective treatment for diabetes-associated complications. For example, we have found a potential …

Privacy Setting Recommendation For Image Sharing, Jun Yu, Zhenzhong Kuang, Zhou Yu, Dan Lin, Jianping Fan

Computer Science Faculty Research & Creative Works

This paper aims to simultaneously consider two inseparable issues for privacy setting recommendation: (1) sensitiveness of visual content of the images being shared; and (2) trustworthiness of users being granted. First, an object-based approach is developed for image content sensitiveness (privacy) representation. Secondly, the users on a social network are clustered into a set of representative social groups to generate a discriminative dictionary for user trustworthiness characterization. Finally, a tree classifier is trained hierarchically to recommend appropriate privacy settings for image sharing.

2-D And 3-D Mapping Of Soil And Rock Structure In Karst Terrain Of Southwestern Missouri Using The Non-Invasive Electrical Resistivity Tomography Method (Ert), Diya Ali Ahmad Alfuqara

Masters Theses

"Electrical resistivity tomography data were acquired in an extensively karstic area of southwestern Missouri. The interpretation of the electrical resistivity tomography data was constrained by multichannel analysis of surface wave data and limited boring control. The objective of the study was to determine if variations in the moisture content of the soil and shallow rock are related to ground surface topography. Analysis of the acquired electrical resistivity tomography data showed that resistivity values of soil and shallow rock beneath and in proximity to identified natural and man-made surface run-off pathways are typically low compared to the resistivity values of soil …

Leveraging Knowledge At Startups, Amruta Anil Ranade

Masters Theses

"Startups contribute to the economy and job creation in the United States. One of the primary assets of startups is tacit knowledge of the employees of the startup. Technical communicators can help startups capture, share, and leverage the tacit knowledge at startups. Technical communicators could benefit from learning how knowledge management initiatives at startups work. The current study is an ethnographic case-study that was conducted at a fast-growing startup in California.

The data for the study was collected through observations, informal and semi-structured formal interviews with participants, and feedback from customers of the startup. The collected data was analyzed based …

Analysis And Implementation Of Accident Tolerant Nuclear Fuels, Benjamin Joseph Prewitt

Masters Theses

"To improve the reliability and robustness of LWR, accident tolerant nuclear fuels and cladding materials are being developed to possibly replace the current UO₂/zirconium system. This research highlights UN and U₃Si₂, two of the most favorable accident tolerant fuels being developed. To evaluate the commercial feasiblilty of these fuels, two areas of research were conducted. Chemical fabrication routes for both fuels were investigated in detail, considering UO₂ and UF₆ as potential starting materials. Potential pathways for industrial scale fabrication using these methods were discussed.

Neutronic performance of 70%UN-30%U₃Si₂ composite …

Media Optimization, Scale-Up And Repeated Fed-Batch Operations For The Production Of 1,3-Propanediol From Glycerol By Halanaerobium Hydrogeniformans, Shivani Kalia

Masters Theses

"The development of renewable energy sources, such as biofuels, is of great interest in today's world due to depletion of fossil fuels and concerns about climate change. The production of the main by-product, crude glycerol, in biodiesel production presents an opportunity for the production of industrially relevant commodities. Crude glycerol in biodiesel waste is highly impure and possesses high salt concentrations and alkalinity, making it infeasible for direct industrial utilization. Moreover, current glycerol purification methods are highly cost-intensive, necessitating a search for cost-effective approaches that are feasible to employ. Genome data analysis of Halanaerobium hydrogeniformans, revealed the metabolic capability …

Overview Of Co₂ Leakage Problems And Sealants For Co₂ Leakage Remediation, Shudai Peng

Masters Theses

"Excessive Carbon Dioxide (CO₂) emission has become a serious issue and caused lots of environmental problems. Carbon Capture and Storage (CCS) program has been developed to reduce the CO₂ content in the atmosphere. CO₂ storage has been targeted mainly on depleted oil or gas reservoirs and deep saline aquifers. However, leakage could occur through wellbores, cap rocks, formation faults, and fractures during and after CO₂ injection. To minimize the risk, different types of sealants have been investigated to prevent CO₂ leaks. The aim of this thesis is to provide a comprehensive review of the materials which could be used as …

Investigating The Sources And Dynamics Of Escherichia Coli In A Missouri Ozarks Watershed, Kaleb Bassett

Masters Theses

"Escherichia coli, an intestinal bacterium, can serve as an indication of the presence of pathogenic microorganisms in water systems used by humans for recreation, agriculture, or drinking water. Many aquatic systems in the United States exceed the E. coli standard, set by the Environmental Protection Agency, for safe drinking water and recreational use. During 2016, a water sampling program was established in the Mill Creek watershed, a rural watershed located near the city of Newburg in Phelps County, Missouri. Water samples were collected before, during, and after storms throughout the year to examine the relationship between E. coli …

Integrating Microgels And Low Salinity Waterflooding To Improve Conformance Control In Fractured Reservoirs, Ali Alhuraishawy, Mingzhen Wei, Baojun Bai, Abdullah Almansour

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The recovery from fractured reservoirs is usually low. The areal heterogeneity is one result of the fractured reservoir. Low salinity waterflooding (LSWF) and preformed particle gel (PPG) have recently investigated by some researchers. The main objective of this study was to determine whether the combining technologies can improve conformance control in fractured sandstone reservoirs. Semi-transparent five-spot models made of sandstone cores and acrylic plates were built. The effect of low salinity waterflooding on oil recovery was studied. Models were designed with three parallel open fractures. Sodium chloride (1.0, 0.1, 0.01, and 0.001 wt. % NaCl) were used for brine flooding …

Ieee Access Special Section Editorial: Emergent Topics For Mobile And Ubiquitous Systems In Smartphone, Iot, And Cloud Computing Era, Takahiro Hara, Stephan Sigg, Lei Shu, Francesco De Pellegrini, Chiara Petrioli, Sanjay Kumar Madria

Computer Science Faculty Research & Creative Works

No abstract provided.

2017 Scholarly Productivity Report, Missouri University Of Science And Technology

Civil, Architectural and Environmental Engineering Scholarly Productivity Reports

No abstract provided.

Chain Transitive Homeomorphisms On A Space: All Or None, Ethan Akin, Juho Rautio

Mathematics and Statistics Faculty Research & Creative Works

Extending earlier work, we consider when a compact metric space can be realized as the omega limit set of a discrete time dynamical system. This is equivalent to asking when the space admits a chain transitive homeomorphism. We approach this problem in terms of various conditions on the connected components of the space. We also construct spaces where all homeomorphisms are chain transitive.

Synthesis And Characterization Of Carbon Doped Tio2 Photocatalysts Supported On Stainless Steel Mesh By Sol-Gel Method, J. O. Tijani, O. O. Fatoba, T. C. Totito, W. D. Roos, L. F. Petrik

Mining Engineering Faculty Research & Creative Works

This study synthesized pure anatase carbon doped TiO₂ photocatalysts supported on a stainless-steel mesh using a sol-gel solution of 8% polyacrylonitrile (PAN)/dimethylformamide (DMF)/TiCl4. The influence of the pyrolysis temperature and holding time on the morphological characteristics, particle sizes and surface area of the prepared catalyst was investigated. The prepared catalysts were characterized by several analytical methods: high resolution scanning electron microscopy (HRSEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), and X-ray photoelectron spectroscopy (XPS). The XRD patterns showed that the supported TiO2 nanocrystals are typically anatase, polycrystalline and body-centered tetragonal in structure. The EDS and XPS results …

The Clustering Of Galaxies In The Completed Sdss-Iii Baryon Oscillation Spectroscopic Survey: Observational Systematics And Baryon Acoustic Oscillations In The Correlation Function, Ashley J. Ross, Florian Beutler, Shun Saito, For Full List Of Authors, See Publisher's Website.

Physics Faculty Research & Creative Works

We present baryon acoustic oscillation (BAO) scale measurements determined from the clustering of 1.2 million massive galaxies with redshifts 0.2 < z < 0.75 distributed over 9300 deg², as quantified by their redshift-space correlation function. In order to facilitate these measurements, we define, describe, and motivate the selection function for galaxies in the final data release (DR12) of the SDSS III Baryon Oscillation Spectroscopic Survey (BOSS). This includes the observational footprint, masks for image quality and Galactic extinction, and weights to account for density relationships intrinsic to the imaging and spectroscopic portions of the survey. We simulate the observed systematic trends in mock galaxy samples and …

Updated Criterion To Select Particle Size Distribution Of Lost Circulation Materials For An Effective Fracture Sealing, Mortadha Alsaba, Mohammed F. Al Dushaishi, Runar Nygaard, Olav Magnar Nes, Arild Saasen

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

This paper presents a new criterion to select particle size distribution (PSD) for an effective fracture sealing. The method was developed based on a comprehensive laboratory investigation that was conducted to determine the relationship between effectiveness of different lost circulation material (LCM) treatments in terms of the sealing efficiency and PSD. The results were compared with the current selection methods, which were developed to enhance the bridging capabilities for drill-in fluid, to investigate their applicability in designing effective treatments for fracture sealing. A statistical investigation was carried out to develop new criteria that suggest PSD based on the expected fracture …

Analysis Of Ior Pilots In Bakken Formation By Using Numerical Simulation, Dheiaa Alfarge, Mingzhen Wei, Baojun Bai, Mortadha Alsaba

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Bakken is the most productive formation among unconventional plays in North America. This formation has 7.4 billion barrels of recoverable oil. However, the primary oil recovery is still low as 5-10%. Miscible natural gas and carbon dioxide (CO₂) might be the most two potential strategies to improve oil recovery in such complex play. In this study, some of the IOR pilots which have been conducted in Montana, North Dakota, and South Saskatchewan have been presented. The performance results of these pilots in US-Bakken versus Canadian-Bakken have been compared. Moreover, the reasons beyond the successful IOR pilots in Canadian-Bakken …

Successful Field Application Of A New Polymer Flooding Technique Suitable For Mature Oilfields Against Low-Oil-Price Background - A Case Study From East China, X. Wu, Y. Wu, C. Xiong, H. Xu, X. Jia, L. Shao, Y. Xiong, J. Zhang, A. Wang, H. Xu, J. Tian, Baojun Bai, X. Tian

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

DGXJ is a sandstone reservoir with temperature of 113 °C, salinity of 36235mg/L, and calcium and magnesium content of 1152mg/L and 30mg/L respectively. The reservoir is not only vertically multilayered and severe heterogeneous, but also witnesses water flowing channels, irregular and imperfect injecting production well patterns, high recovery degree (43%) and high water cut (97%). A new particle-type polymer (SMG) slug combined several small linked-polymer-gel (LPG)slugs and pregelled swellable particle (PSP) was applied during 2011-2015 and achieved remarkable technical and economic effect. The application area is composed of 16 injection wells and 22 production wells. Among the 22 wells, 17 …

A Pore Water Pressure Diffusion Model To Predict Formwork Pressure Exerted By Freshly Mixed Concrete, Chan Kyu Park, Jae Hong Kim, Seong Ho Han

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The formwork pressure exerted by freshly mixed concrete is one of the most important considerations in ensuring the safety of construction in the field. The formwork pressure also affects the quality of concrete structures, determining the final shape of concrete members. Previous studies on the form pressure mostly investigated the intrinsic material effect. For example, the use of self-consolidating concrete increases the maximum pressure on the formwork. The extrinsic factor of a formwork system itself has rarely been considered. In the mockup tests and theoretical evaluations, it is identified that the bleed water-out controlled by the formwork tightness is critical. …

The Ill-Nitrides As A Universal Compound Semiconductor Material: A Review, Chuanle Zhou, Amirhossein Ghods, Vishal G. Saravade, Paresh V. Patel, Kelcy L. Yunghans, Cameron Ferguson, Yining Feng, Xiaodong Jiang, Bahadir Kucukgok, Na Lu, Ian T. Ferguson

Electrical and Computer Engineering Faculty Research & Creative Works

III-nitrides are attracting considerable attention as promising materials for a wide variety of applications due to their wide coverage of direct bandgap range, high electron mobility, high thermal stability and many other exceptional properties. The light-emitting diodes based on Ill-nitrides revolutionize the solid-state lighting industry. Ill-nitrides based solar cells, and thermoelectric generators support the sustainable energy progress, and the III-nitrides are better alternatives for power and radio frequency (RF) electronics compared with silicon. The doped Ill-nitrides' magnetic properties and sensitivity to radiation can contribute to novel spintronic and nuclear detection devices. This paper will review Ill-nitride material properties and their …

No-Boundary Thinking In Bioinformatics, Jason H. Moore, Steven F. Jennings, Casey S. Greene, Lawrence E. Hunter, Andy D. Perkins, Clarlynda Williams-Devane, Donald C. Wunsch, Zhongming Zhao, Xiuzhen Huang

Electrical and Computer Engineering Faculty Research & Creative Works

The following sections are included:
Bioinformatics is a Mature Discipline
The Golden Era of Bioinformatics Has Begun
No-Boundary Thinking in Bioinformatics
References

Electron Impact Excitation-Ionization Of Molecules, Esam Abobakr A. Ali

Doctoral Dissertations

"In the last few decades, the study of atomic collisions by electron-impact has made significant advances. The most difficult case to study is electron impact ionization of molecules for which many approximations have to be made and the validity of these approximations can only be checked by comparing with experiment.

In this thesis, I have examined the Molecular three-body distorted wave (M3DW) or Molecular four-body distorted wave (M4DW) approximations for electron-impact ionization. These models use a fully quantum mechanical approach where all particles are treated quantum mechanically and the post collision interaction (PCI) is treated to all orders of perturbation. …

A Harmonic M-Factorial Function And Applications, Reginald Alfred Brigham Ii

Doctoral Dissertations

"We offer analogs to the falling factorial and rising factorial functions for the set of harmonic numbers, as well as a mixed factorial function called the M-factorial. From these concepts, we develop a harmonic analog of the binomial coefficient and an alternate expression of the harmonic exponential function and establish several identities. We generalize from the harmonic numbers to a general time scale and demonstrate how solutions to some second order eigenvalue problems and partial dynamic equations can be constructed using power series built from the M-factorial function"--Abstract, page iii.

Magneto Inductive Communication System For Underwater Wireless Sensor Networks, Niaz Ahmed

Doctoral Dissertations

"Underwater wireless sensor networks have found a number of applications in underwater environment monitoring, infrastructure monitoring, military applications and ocean exploration. Among the four possible means of underwater wireless communication, namely acoustic, electromagnetic (EM), magneto-inductive (MI) and optics communication, MI communication enjoys the advantages of being low cost and robust equally in air, water and soil. This dissertation presents design and implementation of a low-power and low-cost MI sensor network node that is suited for long-term deployment of underwater and underground infrastructure monitoring, such as bridge scour and levee scour monitoring. The designed MI sensor node combat the directionality of …

Screening Guidelines And Data Analysis For The Application Of In-Situ Polymer Gels For Injection Well Conformance Improvement, Munqith Naeem Rashak Aldhaheri

Doctoral Dissertations

"Excessive water production represents a major industry challenge because of its serious economic and environmental impacts. Polymer gels have been effectively applied to mitigate water production and extend the productive lives of mature oilfields. However, selecting a proper gel technology for a given reservoir is a challenging task for reservoir engineers because of the associated geological and technical complexities and the absence of efficient screening tools.

A comprehensive review for the worldwide gel field projects was conducted to develop an integrated systematic methodology that determines the applicability of three injection well gel technologies including bulk gels, colloidal dispersion gels, and …

In-Situ Assessment Of Concrete Bridge Decks And Pavements Using Stress-Wave Based Methods, Mengxing Li

Doctoral Dissertations

"Concrete infrastructure of United States is aging and deteriorating. Accurate assessment the condition of concrete infrastructure is critical for its maintenance and rehabilitation. Stress-wave based methods, including ultrasonic surface wave (USW) and impact echo (IE), are becoming popular for characterizing defects and mechanical properties of concrete infrastructures. In this dissertation, a comprehensive literature review of seismic wave theory and common types of defects identified in concrete infrastructures, as well as stress-wave based methods used for concrete infrastructure monitoring and characterizing on a selected concrete bridge deck and two concrete pavement segments are present. The utility and reliability of both methods …

Novel Applications Of Pulse Pre-Pump Brillouin Optical Time Domain Analysis For Behavior Evaluation Of Structures Under Thermal And Mechanical Loading, Yi Bao

Doctoral Dissertations

"This study aims to: (1) develop an analytical model for the strain transfer effect of distributed fiber optic sensors in a uniform or non-uniform stress field; (2) develop a measurement approach to monitor strains in concrete and detect damage (e.g. crack and delamination) in bonded and unbonded concrete overlays; (3) characterize the strain and temperature sensitivities of distributed fiber optic sensors at elevated temperatures; (4) develop a thermal annealing approach to enhance the thermal stability and temperature sensitivity of the distributed sensors; and (5) apply the distributed sensors to assess structural behaviors of concrete and steel structures exposed to fire. …

Application Of Quantum Monte Carlo Methods To Molecular Potential Energy Surfaces, Andrew Douglas Powell

Doctoral Dissertations

"Various computational methods have been used to generate potential energy surfaces, which can help us simulate and interpret how atoms or molecules behave during a chemical reaction. For accurate work, ab initio wavefunction methods have traditionally been used, which have some disadvantages. For example, highly accurate methods scale poorly with system size (n⁷ or higher) and are mostly not well parallelized for calculations with multiple processors. One alternative method that has more favorable scaling with system size and is well parallelized is a computational technique called quantum Monte Carlo (QMC). QMC methods scale with the number of electrons as …

Randomized Encoding Of Combinational And Sequential Logic For Resistance To Hardware Trojans, Travis Edward Schulze

Doctoral Dissertations

"Globalization of micro-chip fabrication has opened a new avenue of cyber-crime. It is now possible to insert hardware Trojans directly into a chip during the manufacturing process. These hardware Trojans are capable of destroying a chip, reducing performance or even capturing sensitive data. To date, defensive methods have focused on detection of the Trojan circuitry or prevention through design for security methods.

This dissertation presents a shift away from prevention and detection to a design methodology wherein one no longer cares if a Trojan is present or not. The Randomized Encoding of Combinational Logic for Resistance to Data Leakage or …

Optimal Electric Vehicle Scheduling : A Co-Optimized System And Customer Perspective, Maigha

Doctoral Dissertations

"Electric vehicles provide a two pronged solution to the problems faced by the electricity and transportation sectors. They provide a green, highly efficient alternative to the internal combustion engine vehicles, thus reducing our dependence on fossil fuels. Secondly, they bear the potential of supporting the grid as energy storage devices while incentivizing the customers through their participation in energy markets. Despite these advantages, widespread adoption of electric vehicles faces socio-technical and economic bottleneck. This dissertation seeks to provide solutions that balance system and customer objectives under present technological capabilities. The research uses electric vehicles as controllable loads and resources. The …

Smart Rocks For Bridge Scour Monitoring -- Design And Localization Using Electromagnetic Techniques And Embedded Orientation Sensors, Andro Radchenko

Doctoral Dissertations

"River bridge scour is an erosion process in which flowing water removes sediment materials (such as sand, rocks) from a bridge foundation, river beds and banks. As a result, the level of the river bed near a bridge pier is lowering such that the bridge foundation stability can be compromised, and the bridge can collapse. The scour is a dynamic process, which can accelerate rapidly during a flood event. Thus, regular monitoring of the scour progress is necessary to be performed at most river bridges. Present techniques are usually expensive, require large man/hour efforts, and often lack the real-time monitoring …