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Analysis Of 1,4 Dioxane In Plants, Briannah Spisak Apr 2024

Analysis Of 1,4 Dioxane In Plants, Briannah Spisak

Undergraduate Research Conference at Missouri S&T

Missouri S& T collaborates with University of Iowa on projects to identify the presence of 1,4 Dioxane in tree core samples. The research group will replicate the situation in smaller reactors on campus. The following materials will be used: conetainers, willow cuttings, biochar, and perlite. The plants will be dosed with 1,4-Dioxane and analyzed with Gas ChromatographyMass Spectrometry (GCMS). Plant growth and health will be monitored and related to growth conditions and pollutant exposure. Larger mesocosms will be dosed over the summer and will have in-planta analysis as well. To replicate the field site, exact biochar and perlite from the …


Floating Treatment Wetlands For Zinc Phytoremediation, Grace Duong Apr 2024

Floating Treatment Wetlands For Zinc Phytoremediation, Grace Duong

Undergraduate Research Conference at Missouri S&T

Stormwater pollution from urban and mining areas can pose challenges to downstream waters because of zinc contamination. Floating treatment wetlands (FTWs) have demonstrated the ability to mitigate nutrient and metal contamination. To investigate the effectiveness of native Missouri plants in FTWs, fourteen 10-liter mesocosms were constructed, dosed with nutrients, and placed in a greenhouse. Four mesocosms acted as controls, five contained pickerelweed, and five contained palm sedge. After one week of acclimation, mesocosms were dosed with ZnCl2 in concentrations of 0, 5, and 10 mg/L of zinc. Objectives of this study include characterizing zinc immobilization and assessing both pickerelweed and …


Iron Doped Zeolitic Materials For Propane Dehydrogenation Catalyst, Emily Cahill, Amitava Choudhury Apr 2024

Iron Doped Zeolitic Materials For Propane Dehydrogenation Catalyst, Emily Cahill, Amitava Choudhury

Undergraduate Research Conference at Missouri S&T

This research describes the synthesis of iron-doped zeolitic catalysts for the transformation of propane to propylene. The goal of this research is to develop a dehydrogenation catalyst to convert shale-gas derived cheap propane feedstock to economically valuable propylene, while at the same time making this catalyst sustainable and non-toxic to the environment. Fedoped zeolitic frameworks have shown promising activity in percentage of conversion and in selectivity. In our study we analyzed zeolites ZSM-5 and AIP0-5. These were chosen because they have differences in pore structure , channel sizes, and connectivity between channels. Most importantly the differences in the chemistry as …


Evaluation Of Phosphorus Uptake Within Aquatic Plants For The Use Of Nutrient Removal, Grace Willbanks Apr 2024

Evaluation Of Phosphorus Uptake Within Aquatic Plants For The Use Of Nutrient Removal, Grace Willbanks

Undergraduate Research Conference at Missouri S&T

Stormwater runoff from urban areas can lead to excess nutrients, such as phosphorus or nitrogen, in our waterways. These waste nutrients can lead to overgrowth of algae and plants, deoxygenation of ponds and streams, and death of the aquatic life in these important ecosystems. Currently, floating treatment wetlands are being used to combat these excess nutrients, combining a floating element with an absorptive media, either man-made or natural aquatic plants, into a model to float on an impacted lake. In this research project, multiple small-scale microcosm level experiments were run with different native aquatic plants to test their uptake ability …


Feasibility Of Using Hemp Fiber Reinforcement In 3d Printing Cementitious Composites, Zachary Baldwin, Ali Fasihi, Nicolas Ali Libre Apr 2024

Feasibility Of Using Hemp Fiber Reinforcement In 3d Printing Cementitious Composites, Zachary Baldwin, Ali Fasihi, Nicolas Ali Libre

Undergraduate Research Conference at Missouri S&T

This research is aimed at investigating the f~asibility of implementing natural fibers, such as hemp fibers, in lieu of synthetic fibers as sustainable and environmentally friendly resources in concrete production. In the first stage of this study, a surface treatment was applied to hemp fibers 12 mm± 2 mm in length using a 5 wt% sodium hydroxide (NaOH) solution to determine the effect treated hemp fibers have on cementitious composites. Additionally, three cement mortars were made with different fiber ratios (0.75%, 1.5%, 3%) to determine the optimal hemp fiber content of the mortars. Concrete samples were cast also concrete filaments …


Density Fluctuations Measurements In Supersonic Flows, Allie Dingfield, Davide Vigano Apr 2024

Density Fluctuations Measurements In Supersonic Flows, Allie Dingfield, Davide Vigano

Undergraduate Research Conference at Missouri S&T

Turbulence in compressible flows plays a major role in a variety of aerospace applications. However, due to fluctuating thermodynamic quantities, compressible turbulence is challenging to analyze. Of these quantities, density fluctuations are of high importance due to their role in describing turbulence. A method to obtain quantitative measurements of density fluctuations has been developed using the optical technique of shadowgraph imaging. Shadowgraph imaging has frequently been used to obtain qualitative information about density gradients in fluids. However, quantitative application of these methods is much less common. The quantitative shadowgraph method presented here relates the light intensity variations in an image …


Using Virtual Reality Technologies In Built Environment Education, Rebekah Floyd, Kayla Walters, Stuart Werner Baur Apr 2024

Using Virtual Reality Technologies In Built Environment Education, Rebekah Floyd, Kayla Walters, Stuart Werner Baur

Undergraduate Research Conference at Missouri S&T

Virtual reality (VR) offers transformative potential in built environment education, including human-made surroundings like buildings and infrastructure. This review explores VR's benefits, challenges, and trends in this field. VR fosters immersive learning, allowing students to explore architectural designs and urban planning scenarios. It provides hands-on experiences, enhancing spatial understanding and critical thinking. Simulations enable safe experimentation with design ideas and construction techniques without the real-life limitations or risk holding students back. However, challenges include high costs, technical limitations, and the need for educator training. Ensuring accessibility for all students is crucial. Despite challenges, VR's potential to revolutionize built environment education …


Amendments For Enhanced Remediation Of 1.4 Dioxane And Advances In Application Of Phytoforensics, Kaylee Denbo, Briannah Spisak, Joel Gerard Burken Apr 2024

Amendments For Enhanced Remediation Of 1.4 Dioxane And Advances In Application Of Phytoforensics, Kaylee Denbo, Briannah Spisak, Joel Gerard Burken

Undergraduate Research Conference at Missouri S&T

Missouri S& T collaborates with University of Iowa on projects to identify the presence of 1,4 Dioxane in tree core samples. The research group will replicate the situation in smaller reactors on campus. The following materials will be used: conetainers, willow cuttings, biochar, and perlite. The plants will be dosed with 1,4-Dioxane and analyzed with Gas ChromatographyMass Spectrometry (GCMS). Plant growth and health will be monitored and related to growth conditions and pollutant exposure. Larger mesocosms will be dosed over the summer and will have in-planta analysis as well. To replicate the field site, exact biochar and perlite from the …


Experiential Learning In Rf Circuit Design, Benjamin Cuebas Apr 2024

Experiential Learning In Rf Circuit Design, Benjamin Cuebas

Undergraduate Research Conference at Missouri S&T

This research project will explore the intricacies of Radio Frequency (RF) circuitry design, demonstrating acquired insights by constructing a discrete RF amplifier with digital input attenuation control. The study will delve into a multitude of RF topics such as serial communication, digital data storage, transmission line theory, impedance matching, network parameters, amplifier classes, and Smith chart analysis. The RF amplifier will be designed to have an approximately 15dB input gain/attenuation digitally controlled by an external microcontroller. The device will operate at 50 MHz, in the VHF frequency range, with an input and output impedance of 50 . A network analyzer …


19th Annual Undergraduate Research Conference (Ugrc) - 2024, Missouri University Of Science And Technology Apr 2024

19th Annual Undergraduate Research Conference (Ugrc) - 2024, Missouri University Of Science And Technology

Undergraduate Research Conference at Missouri S&T

No abstract provided.


Editorial For Special Issue “Design, Modeling, Optimization And Control Of Flotation Process”, Fardis Nakhaei, Ahmad Hassanzadeh, Luis A. Cisternas Apr 2024

Editorial For Special Issue “Design, Modeling, Optimization And Control Of Flotation Process”, Fardis Nakhaei, Ahmad Hassanzadeh, Luis A. Cisternas

Mining Engineering Faculty Research & Creative Works

No abstract provided.


Editorial For Special Issue “Design, Modeling, Optimization And Control Of Flotation Process”, Fardis Nakhaei, Ahmad Hassanzadeh, Luis A. Cisternas Apr 2024

Editorial For Special Issue “Design, Modeling, Optimization And Control Of Flotation Process”, Fardis Nakhaei, Ahmad Hassanzadeh, Luis A. Cisternas

Mining Engineering Faculty Research & Creative Works

No abstract provided.


Experimental, Computational, And Machine Learning Methods For Prediction Of Residual Stresses In Laser Additive Manufacturing: A Critical Review, Sung Heng Wu, Usman Tariq, Ranjit Joy, Todd Sparks, Aaron Flood, Frank W. Liou Apr 2024

Experimental, Computational, And Machine Learning Methods For Prediction Of Residual Stresses In Laser Additive Manufacturing: A Critical Review, Sung Heng Wu, Usman Tariq, Ranjit Joy, Todd Sparks, Aaron Flood, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In recent decades, laser additive manufacturing has seen rapid development and has been applied to various fields, including the aerospace, automotive, and biomedical industries. However, the residual stresses that form during the manufacturing process can lead to defects in the printed parts, such as distortion and cracking. Therefore, accurately predicting residual stresses is crucial for preventing part failure and ensuring product quality. This critical review covers the fundamental aspects and formation mechanisms of residual stresses. It also extensively discusses the prediction of residual stresses utilizing experimental, computational, and machine learning methods. Finally, the review addresses the challenges and future directions …


Microwave Holography For Emi Source Imaging, Xin Yan, Jiangshuai Li, Wei Zhang, Kaustav Ghosh, Philippe Sochoux, Daryl G. Beetner, Victor Khilkevich Apr 2024

Microwave Holography For Emi Source Imaging, Xin Yan, Jiangshuai Li, Wei Zhang, Kaustav Ghosh, Philippe Sochoux, Daryl G. Beetner, Victor Khilkevich

Electrical and Computer Engineering Faculty Research & Creative Works

Emission Source Microscopy Technique Can Be Utilized to Localize the Radiation Sources in Complex and Electrically Large Electronic Systems. in the Two-Dimensional Emission Source Microscopy Algorithm, Both Magnitude and Phase of the Field Need to Be Measured, and a Vector Network Analyzer or an Oscilloscope Has to Be Used as a Receiver, Resulting in Reduced Signal-To-Noise Ratio and Longer Measurement Time Compared to a Spectrum Analyzer (SA). in This Article, a Phase less Electromagnetic Interference Source Imaging Method is Proposed based on Microwave Holography. the Field Produced by the Device under Test is Not Measured Directly, Instead, the Interference Pattern …


Convolutional Spiking Neural Networks For Intent Detection Based On Anticipatory Brain Potentials Using Electroencephalogram, Nathan Lutes, V. Sriram Siddhardh Nadendla, K. Krishnamurthy Apr 2024

Convolutional Spiking Neural Networks For Intent Detection Based On Anticipatory Brain Potentials Using Electroencephalogram, Nathan Lutes, V. Sriram Siddhardh Nadendla, K. Krishnamurthy

Computer Science Faculty Research & Creative Works

Spiking neural networks (SNNs) are receiving increased attention because they mimic synaptic connections in biological systems and produce spike trains, which can be approximated by binary values for computational efficiency. Recently, the addition of convolutional layers to combine the feature extraction power of convolutional networks with the computational efficiency of SNNs has been introduced. This paper studies the feasibility of using a convolutional spiking neural network (CSNN) to detect anticipatory slow cortical potentials (SCPs) related to braking intention in human participants using an electroencephalogram (EEG). Data was collected during an experiment wherein participants operated a remote-controlled vehicle on a testbed …


Insight Into Uniform Filming Of Lif-Rich Interphase Via Synergistic Adsorption For High-Performance Lithium Metal Anode, Yufang He, Li Wang, Aiping Wang, Bo Zhang, Hiep Pham, Jonghyun Park, Xiangming He Apr 2024

Insight Into Uniform Filming Of Lif-Rich Interphase Via Synergistic Adsorption For High-Performance Lithium Metal Anode, Yufang He, Li Wang, Aiping Wang, Bo Zhang, Hiep Pham, Jonghyun Park, Xiangming He

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Multi-scale simulation is an important basis for constructing digital batteries to improve battery design and application. Lif-rich solid electrolyte interphase (sei) is experimentally proven to be crucial for the electrochemical performance of lithium metal batteries. However, the lif-rich sei is sensitive to various electrolyte formulas and the fundamental mechanism is still unclear. Herein, the structure and formation mechanism of lif-rich sei in different electrolyte formulas have been reviewed. On this basis, it further discussed the possible filming mechanism of lif-rich sei determined by the initial adsorption of the electrolyte-derived species on the lithium metal anode (lma). It proposed that individual …


Risk–Reward Share Allocation Under Different Integrated Project Delivery Relational Structures: A Monte-Carlo Simulation And Cooperative Game Theoretic Solutions Approach, Radwa Eissa, Mohamad Abdul Nabi, Islam H. El-Adaway Apr 2024

Risk–Reward Share Allocation Under Different Integrated Project Delivery Relational Structures: A Monte-Carlo Simulation And Cooperative Game Theoretic Solutions Approach, Radwa Eissa, Mohamad Abdul Nabi, Islam H. El-Adaway

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Sharing of risks and rewards is considered to be one of the key benefits and principles of integrated project delivery (IPD). Despite its importance, risk–reward strategies are not implemented widely in IPD construction projects due to the lack of a well-defined basis for establishing adequate allocation plans. This paper fills this knowledge gap. This research followed a multistep methodology. First, the authors calculated the risk control valuations of all potential combinations of coalitions for IPD stakeholders. This was performed using interrelated steps of risk identification and quantification, risk assignment based on associated contractual analysis, establishment of a coordination network, and …


Seismicity Characteristics Of The Gulf Of Aqaba Seismogenic Zone And Their Hazard Implications In Northwestern Saudi Arabia, Ali Abdelfattah, Mohamed Ezzelarab, Hazem Badreldin, Hassan Alzahrani, Saleh Qaysi, Bassam Abuamarah, Neil Lennart Anderson Apr 2024

Seismicity Characteristics Of The Gulf Of Aqaba Seismogenic Zone And Their Hazard Implications In Northwestern Saudi Arabia, Ali Abdelfattah, Mohamed Ezzelarab, Hazem Badreldin, Hassan Alzahrani, Saleh Qaysi, Bassam Abuamarah, Neil Lennart Anderson

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The seismogenic characteristics of the Gulf of Aqaba zone have been assessed using the maximum likelihood method to estimate various earthquake recurrence parameters. These parameters encompass the β-value, annual recurrence rate (λ), and maximum probable magnitude (Mmax). This assessment has identified three sub-seismogenic zones, each corresponding to specific structural faults within the Gulf. These zones are associated with the Aragonese, Arnona and Aqaba faults, delineating pull-apart basin structures in the Gulf of Aqaba. An updated earthquake catalogue has been compiled using a unified moment magnitude (Mw) scale to improve the analysis, established by developing two empirical relationships. According to the …


Comprehensive Understanding Of Factors Impacting Competitive Construction Bidding, Muaz O. Ahmed, Islam H. El-Adaway, Aubrie Caldwell Apr 2024

Comprehensive Understanding Of Factors Impacting Competitive Construction Bidding, Muaz O. Ahmed, Islam H. El-Adaway, Aubrie Caldwell

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Construction competitive bidding has been studied by many researchers; however, their focus was mainly on certain bidding aspects. Thus, despite their value, existing bidding models have limited applicability for various reasons including the non-inclusion of some real-life factors that impact bidding-related decisions. As such, there is a need for identifying a comprehensive list of bidding factors that impact construction bidding-related decisions, studying their associations, and identifying understudied factors to direct future research efforts. This paper fills this knowledge gap. First, the authors conducted a systematic selection of 124 construction bidding-related articles published within the past 40 years. Second, the authors …


Utilizing Ensemble Learning In The Classifications Of Ductile And Brittle Failure Modes Of Uhpc Strengthened Rc Members, Woubishet Zewdu Taffese, Yanping Zhu, Genda Chen Apr 2024

Utilizing Ensemble Learning In The Classifications Of Ductile And Brittle Failure Modes Of Uhpc Strengthened Rc Members, Woubishet Zewdu Taffese, Yanping Zhu, Genda Chen

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study aims to achieve the swift and precise classification of ductile and brittle failure modes in flexural reinforced concrete (RC) members, specifically those with tension sides strengthened by ultrahigh performance concrete (UHPC). Employing six ensemble learning techniques—Bagging, Random Forest, AdaBoost, Gradient Boosting, XGBoost, and LightGBM—the authors utilize a comprehensive dataset comprising 14 features, which include manually labeled failure modes obtain from load–deflection curves. The model training spans four scenarios, varying in the inclusion or exclusion of features describing the cross-sectional area of RC members and moment resistance. XGBoost emerges as the most effective classifier, achieving an impressive 84% accuracy …


Effects Of Rest Time And Curing Regime On Short- And Long-Term Strength Of Class C Fly Ash-Based Alkali-Activated Mortars, Cedric Kashosi, Ahmed Gheni, Eslam Gomaa, Mohamed Elgawady Apr 2024

Effects Of Rest Time And Curing Regime On Short- And Long-Term Strength Of Class C Fly Ash-Based Alkali-Activated Mortars, Cedric Kashosi, Ahmed Gheni, Eslam Gomaa, Mohamed Elgawady

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study investigated how different rest times affect the strength development of fly-ash-based alkali-activated mortar (aam) over a period of 90 days. Two types of fly ash with varying calcium oxide contents of 37 and 21% were used. The rest times ranged from 2 to 36 h, and three curing methods (ambient, oven, and steam) were tested. The results showed that the rest time significantly influenced the compressive strength of the aam. The optimal rest time was found to be between 12 and 30 h depending on the curing method and fly ash type. Beyond this range, there were only …


Bioaerosol Size As A Potential Determinant Of Airborne E. Coli Viability Under Ultraviolet Germicidal Irradiation And Ozone Disinfection, Weixing Hao, Yue-Wern Huang, Yang Wang Apr 2024

Bioaerosol Size As A Potential Determinant Of Airborne E. Coli Viability Under Ultraviolet Germicidal Irradiation And Ozone Disinfection, Weixing Hao, Yue-Wern Huang, Yang Wang

Biological Sciences Faculty Research & Creative Works

Ultraviolet germicidal irradiation (UVGI) and ozone disinfection are crucial methods for mitigating the airborne transmission of pathogenic microorganisms in high-risk settings, particularly with the emergence of respiratory viral pathogens such as SARS-CoV-2 and avian influenza viruses. This study quantitatively investigates the influence of UVGI and ozone on the viability of E. coli in bioaerosols, with a particular focus on how E. coli viability depends on the size of the bioaerosols, a critical factor that determines deposition patterns within the human respiratory system and the evolution of bioaerosols in indoor environments. This study used a controlled small-scale laboratory chamber where E. …


Physical And Chemical Methods To Assess Performance Of Tpo-Modified Asphalt Binder, Rebecca M. Herndon, Jay Balasubramanian, Klaus Woelk, Magdy Abdelrahman Apr 2024

Physical And Chemical Methods To Assess Performance Of Tpo-Modified Asphalt Binder, Rebecca M. Herndon, Jay Balasubramanian, Klaus Woelk, Magdy Abdelrahman

Chemistry Faculty Research & Creative Works

The Demand for Effective Asphalt Additives is Growing as Road Infrastructure Ages and More Sustainable Pavement Solutions Are Needed. Tire Pyrolysis Oil (TPO) is an Example Material that Has Been Gaining Attention as a Potential Asphalt Additive. While Physical Performance Grade (PG) Temperatures Are the Predominant Performance Requirements for Asphalt Binders, Chemical Properties Are Also Significant in the Evaluation of Asphalt Performance. There is a Need to Chemically Characterize the Aging of Asphalt Binders Modified with TPO and Link Chemical Changes in Binder Components to Binder Performance. This Study Compares 2%, 4%, and 8% TPO and Asphalt Binder Blends Via …


Multifunctional Models In Digital And Physical Twinning Of The Built Environment—A University Campus Case Study, Genda Chen, Ibrahim Alomari, Woubishet Zewdu Taffese, Zhenhua Shi, Mohammad Hossein Afsharmovahed, Tarutal Ghosh Mondal, Son Nguyen Apr 2024

Multifunctional Models In Digital And Physical Twinning Of The Built Environment—A University Campus Case Study, Genda Chen, Ibrahim Alomari, Woubishet Zewdu Taffese, Zhenhua Shi, Mohammad Hossein Afsharmovahed, Tarutal Ghosh Mondal, Son Nguyen

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The Digital Twin (DT) Concept Has Been Developed for a Single Function in Previous Studies. This Study Aims to Empower DTs with a Layered Integration of Multifunctional Models in the Built Environment. It Develops a Framework of DT Modules in Three Hierarchical Tiers: Region, Asset, and System; Defines a New Concept of the Degree of Digital Twinning (DODT) to the Real World by the Number of Models Enabled by a Common DT Platform; and Enables Spatiotemporal Analysis in Multiple Scales to Couple Nonstructural with Structural Building Components and Connect the Built Environment to Planning Constructions. While the Asset and System …


Cr-Sam: Curvature Regularized Sharpness-Aware Minimization, Tao Wu, Tony Tie Luo, Donald C. Wunsch Mar 2024

Cr-Sam: Curvature Regularized Sharpness-Aware Minimization, Tao Wu, Tony Tie Luo, Donald C. Wunsch

Computer Science Faculty Research & Creative Works

The Capacity to Generalize to Future Unseen Data Stands as One of the Utmost Crucial Attributes of Deep Neural Networks. Sharpness-Aware Minimization (SAM) Aims to Enhance the Generalizability by Minimizing Worst-Case Loss using One-Step Gradient Ascent as an Approximation. However, as Training Progresses, the Non-Linearity of the Loss Landscape Increases, Rendering One-Step Gradient Ascent Less Effective. on the Other Hand, Multi-Step Gradient Ascent Will Incur Higher Training Cost. in This Paper, We Introduce a Normalized Hessian Trace to Accurately Measure the Curvature of Loss Landscape on Both Training and Test Sets. in Particular, to Counter Excessive Non-Linearity of Loss Landscape, …


Mitigation Of Potential Risks In Chemical Laboratories: A Focused Review, Hossein Abedsoltan, Mark B. Shiflett Mar 2024

Mitigation Of Potential Risks In Chemical Laboratories: A Focused Review, Hossein Abedsoltan, Mark B. Shiflett

Chemical and Biochemical Engineering Faculty Research & Creative Works

This review paper presents an analysis of safety practices in chemical laboratories. It encompasses a systematic exploration of various facets including risk assessment, hazard mitigation, and the implementation of safety protocols. Emphasis is placed on the critical role of continuous education and training, advocating a proactive safety culture, and adapting to technological advancements. Additionally, the paper underscores the importance of adhering to regulatory standards, promoting exceeding baseline compliance toward establishing best practices in laboratory safety. This comprehensive approach highlights the dynamic, multifaceted nature of laboratory safety, positioning it as a fundamental aspect of scientific research.


Nitrene-Transfer Chemistry To C-H And C═C Bonds Mediated By Triangular Coinage Metal Platforms Supported By Triply Bridging Pnictogen Elements Sb(Iii) And Bi(Iii), Meenakshi Sharma, Reece M. Fritz, Joseph O. Adebanjo, Zhou Lu, Thomas R. Cundari, Mohammad A. Omary, Amitava Choudhury, Pericles Stavropoulos Mar 2024

Nitrene-Transfer Chemistry To C-H And C═C Bonds Mediated By Triangular Coinage Metal Platforms Supported By Triply Bridging Pnictogen Elements Sb(Iii) And Bi(Iii), Meenakshi Sharma, Reece M. Fritz, Joseph O. Adebanjo, Zhou Lu, Thomas R. Cundari, Mohammad A. Omary, Amitava Choudhury, Pericles Stavropoulos

Chemistry Faculty Research & Creative Works

Tripodal Ligands (TMG3trphen-E) That Feature Heavy Pnictogen Elements (E = Sb(III), Bi(III)) And Tetramethylguanidinyl (TMG) Arms Have Been Explored In Stabilizing Cu(I) And Ag(I) Sites And Facilitating Nitrene-Transfer Chemistry. Compounds [(TMG3trphen-E)M3(Μ-X)3] (M = Cu(I), Ag(I); X = Cl, Br, I) Have Been Generated Upon Extraction Of M3(Μ-X)3 Units From MX Sources, Exhibiting Support Of The Crown-Shaped M3(Μ-X)3 Fragment By M-NTMG Bonds And Triply Bridging E → M3 Interactions. Orbital Interactions Between Cu(I) Sites And NTMG Residues Are More Dominant Than Sb/Bi → Cu3 Donor Interactions Between The Sb 5s Or Bi 6s Orbitals And Admixed Cu 4s/3d Orbitals, With Larger …


Lrs: Enhancing Adversarial Transferability Through Lipschitz Regularized Surrogate, Tao Wu, Tony Tie Luo, Donald C. Wunsch Mar 2024

Lrs: Enhancing Adversarial Transferability Through Lipschitz Regularized Surrogate, Tao Wu, Tony Tie Luo, Donald C. Wunsch

Computer Science Faculty Research & Creative Works

The Transferability of Adversarial Examples is of Central Importance to Transfer-Based Black-Box Adversarial Attacks. Previous Works for Generating Transferable Adversarial Examples Focus on Attacking Given Pretrained Surrogate Models While the Connections between Surrogate Models and Adversarial Trasferability Have Been overlooked. in This Paper, We Propose Lipschitz Regularized Surrogate (LRS) for Transfer-Based Black-Box Attacks, a Novel Approach that Transforms Surrogate Models towards Favorable Adversarial Transferability. using Such Transformed Surrogate Models, Any Existing Transfer-Based Black-Box Attack Can Run Without Any Change, Yet Achieving Much Better Performance. Specifically, We Impose Lipschitz Regularization on the Loss Landscape of Surrogate Models to Enable a Smoother …


The Shock Cone Instabilities And Quasi-Periodic Oscillations Around The Hartle–Thorne Black Hole, Orhan Donmez, Fatih Dogan Mar 2024

The Shock Cone Instabilities And Quasi-Periodic Oscillations Around The Hartle–Thorne Black Hole, Orhan Donmez, Fatih Dogan

Materials Science and Engineering Faculty Research & Creative Works

To explain the observed X-ray data in a black hole–accreting matter system and understand the physical mechanisms behind QPOs, we have numerically modeled the dynamical and oscillation properties of the shock cone formed around both slowly and rapidly rotating Hartle–Thorne black holes, resulting from the mechanism of Bondi–Hoyle–Lyttleton (BHL). According to the numerical simulations, an increase in the quadrupole parameter leads to a decrease in the shock cone opening angle around the black hole. A larger quadrupole parameter results in more matter falling into the black hole within the cone. The combination of the quadrupole parameter and black hole rotation …


Homodimeric Granzyme A Opsonizes Mycobacterium Tuberculosis And Inhibits Its Intracellular Growth In Human Monocytes Via Toll-Like Receptor 4 And Cd14, Valerio Rasi, Kathleen R. Phelps, Keegan R. Paulson, Christopher S. Eickhoff, Mathivanan Chinnaraj, Nicola Pozzi, Marco Di Gioia, Ivan Zanoni, Shubha Shakya, Haley L. Carlson, David A. Ford, Grant R. Kolar, Daniel F. Hoft Mar 2024

Homodimeric Granzyme A Opsonizes Mycobacterium Tuberculosis And Inhibits Its Intracellular Growth In Human Monocytes Via Toll-Like Receptor 4 And Cd14, Valerio Rasi, Kathleen R. Phelps, Keegan R. Paulson, Christopher S. Eickhoff, Mathivanan Chinnaraj, Nicola Pozzi, Marco Di Gioia, Ivan Zanoni, Shubha Shakya, Haley L. Carlson, David A. Ford, Grant R. Kolar, Daniel F. Hoft

Biological Sciences Faculty Research & Creative Works

Mycobacterium tuberculosis (Mtb)-specific γ9δ2 T cells secrete granzyme A (GzmA) protective against intracellular Mtb growth. However, GzmA-enzymatic activity is unnecessary for pathogen inhibition, and the mechanisms of GzmA-mediated protection remain unknown. We show that GzmA homodimerization is essential for opsonization of mycobacteria, altered uptake into human monocytes, and subsequent pathogen clearance within the phagolysosome. Although monomeric and homodimeric GzmA bind mycobacteria, only homodimers also bind cluster of differentiation 14 (CD14) and Toll-like receptor 4 (TLR4). Without access to surface-expressed CD14 and TLR4, GzmA fails to inhibit intracellular Mtb. Upregulation of Rab11FIP1 was associated with inhibitory activity. Furthermore, GzmA colocalized with …