Author Correction: Dense Sampling Of Bird Diversity Increases Power Of Comparative Genomics (Nature, (2020), 587, 7833, (252-257), 10.1038/S41586-020-2873-9), Shaohong Feng, Josefin Stiller, Yuan Deng, Joel Armstrong, Qi Fang, Andrew Hart Reeve, Duo Xie, Guangji Chen, Chunxue Guo, Brant C. Faircloth, Bent Petersen, Zongji Wang, Qi Zhou, Mark Diekhans, Wanjun Chen, Sergio Andreu-Sánchez, Ashot Margaryan, Jason Travis Howard, Carole Parent, George Pacheco, Mikkel Holger S. Sinding, Lara Puetz, Emily Cavill, Ângela M. Ribeiro, Leopold Eckhart, Jon Fjeldså, Peter A. Hosner, Robb T. Brumfield, Les Christidis, Mads F. Bertelsen, Thomas Sicheritz-Ponten, Dieter Thomas Tietze, Bruce C. Robertson

Faculty Publications

In Supplementary Table 1 of this Article, 23 samples (B10K-DU-029-32, B10K-DU-029-33, B10K-DU-029-36 to B10K-DU-029-44, B10K-DU- 029-46, B10K-DU-029-47, B10K-DU-029-49 to B10K-DU-029-53, B10K-DU- 029-75 to B10K-DU-029-77, B10K-DU-029-80, and B10K-DU-030-03; styled in boldface in the revised table) were assigned to the incorrect institution. Supplementary Table 1 has been amended to reflect the correct source institution for these samples, and associated data (tissue, museum ID/source specimen ID, site, state/province, latitude, longitude, date collected and sex) have been updated accordingly. The original table is provided as Supplementary Information to this Amendment, and the original Article has been corrected online.

Α-Cgrp Disrupts Amylin Fibrillization And Regulates Insulin Secretion: Implications On Diabetes And Migraine, Amber L.H. Gray, Aleksandra Antevska, Benjamin A. Link, Bryan Bogin, Susan J. Burke, Samuel D. Dupuy, J. Jason Collier, Zachary A. Levine, Michael D. Karlstad, Thanh D. Do

Division of Basic Science Faculty Publications

Despite being relatively benign and not an indicative signature of toxicity, fibril formation and fibrillar structures continue to be key factors in assessing the structure-function relationship in protein aggregation diseases. The inability to capture molecular cross-talk among key players at the tissue level before fibril formation greatly accounts for the missing link toward the development of an efficacious therapeutic intervention for Type II diabetes mellitus (T2DM). We show that human α-calcitonin gene-related peptide (α-CGRP) remodeled amylin fibrillization. Furthermore, while CGRP and/or amylin monomers reduce the secretion of both mouse Ins1 and Ins2 proteins, CGRP oligomers have a reverse effect on …

Representations Of Female Agency In Medieval French Literature, Mathilde Pointiere

LSU Doctoral Dissertations

This dissertation examines the different ways authors portray female agency in medieval French literature. In focusing on three medieval writers, Chrétien de Troyes, Heldris de Cornouailles and Christine de Pizan, I contend that female agency arises as a result of trauma or crisis. I define my terms as follows: agency is the capacity and intention of performing actions on one’s own behalf. For a fictional character to have agency, therefore, she must be portrayed as having a sense of control and of being the owner of the action she executes. Additionally, I argue that as women characters assume their agency, …

Mental Imagery In Fear Extinction: A Multi-Component Examination Based On Behavioral, Physiological, And Neurological Measures, Xinrui Jiang

LSU Doctoral Dissertations

Imagery has long been utilized in clinical treatments of affective symptoms with the assumption that mental imagery can stand in for its perceptual counterpart and exert regulatory effects over emotional responses. While this assumption has its ground in theoretical framework of mental imagery supported by evidence of neurological overlaps between imagery and perception, and clinical applications of imagery interventions were found to be successful, very little has been done through means of experimental examinations.

This investigation began with a differential fear conditioning study (study 1) to simulate and assess imagery extinction. Results provided support for the efficacy of imagery exposure …

Empowering The Caregiver Network Of Farmers With A Disability: A Case Study Of The North Carolina Agrability Project, Kristoff Minus, Janine Woods, Richie Roberts, Chastity English, Beatriz Rodriguez

Faculty Publications

No abstract provided.

Effects Of Planning And Repeated Writing Interventions On Writing Fluency, Katherine Lea Moore

LSU Doctoral Dissertations

Writing is an essential skill for academic success. Evidence shows students with writing difficulties experience lower overall academic performance (Graham & Perin, 2007). The development of fluent writing is particularly important, as it has been shown to be a strong predictor of global writing quality (Malecki & Jewell, 2003). Limited research exists on writing interventions specifically targeting writing fluency. While performance feedback procedures have been found effective for increasing writing fluency (Hier & Eckert, 2016), interventions such as story-mapping and self-regulation strategy development (SRSD), which target higher order writing skills, have also been shown to improve writing fluency abilities (Harris, …

Lgbtq Youth Homeless Shelter Challenging Perceptions And Interactions With The Built Environment, Mary Oliver

Honors Capstones

No abstract provided.

The Martyrdom And Monster-Ization Of The Mujahideen In The American Christian Mind, Katelyn Prescott

Honors Capstones

No abstract provided.

Green Alga Bicarbonate Transporter And Uses Thereof, James V. Moroney, Marylou C. Machingura, Joanna Bajsa-Hirschel

College of Science Patents

Provided herein are green alga Cia8 polypeptides and the polynucleotides that encode them. Also provided herein are transformed cells and transgenic plants that include one or more of the polynucleotides and/or polypeptides provided herein.

The Modern Plant Breeding Triangle: Optimizing The Use Of Genomics, Phenomics, And Enviromics Data, Jose Crossa, Roberto Fritsche-Neto, Osval A. Montesinos-Lopez, Germano Costa-Neto, Susanne Dreisigacker, Abelardo Montesinos-Lopez, Alison R. Bentley

Faculty Publications

No abstract provided.

Controlling The Orientation Of Fluorescent Dyes Using External Electric Fields, Henry J. Kantrow

Honors Capstones

No abstract provided.

Microparticles And Latexes Prepared Via Suspension Polymerization Of A Biobased Vegetable Oil And Renewable Carboxylic Acid, Anthony Q. Mai, Jackie Davies, Dan Nguyen, Arturo Carranza, Michael Vincent, John A. Pojman

Faculty Publications

© 2020 Wiley Periodicals LLC. Novel bio-based microparticles and latexes are synthesized using green chemistry principles through the reaction of aconitic acid (a sugarcane byproduct) and epoxidized linseed oil (ELO). No volatile solvents have been used, and no initiators are present in this polymerization. Using different agitation techniques, we investigate the particles and latexes formed via suspension polymerization in contrast to bulk dispersion polymerization. With the addition of water and a small amount of surfactant to the ELO and aconitic system, a thermally stable material up to 250°C is created that exhibits adhesive and hydrophobic properties. These microparticle latexes are …

Laser Power Stabilization Via Radiation Pressure, Marina Trad Nery, Jasper R. Venneberg, Nancy Aggarwal, Garrett D. Cole, Thomas Corbitt, Jonathan Cripe, Robert Lanza, Benno Willke

Faculty Publications

This Letter reports the experimental realization of a novel, to the best of our knowledge, active power stabilization scheme in which laser power fluctuations are sensed via the radiation pressure driven motion they induce on a movable mirror. The mirror position and its fluctuations were determined by means of a weak auxiliary laser beam and a Michelson interferometer, which formed the in-loop sensor of the power stabilization feedback control system. This sensing technique exploits a nondemolition measurement, which can result in higher sensitivity for power fluctuations than direct, and hence destructive, detection. Here we used this new scheme in a …

Nitrification Inhibitors Reduce Nitrogen Losses And Improve Soil Health In A Subtropical Pastureland, Yili Meng, Jim J. Wang, Zhuo Wei, Syam K. Dodla, Lisa M. Fultz, Lewis A. Gaston, Ran Xiao, Jong Hwan Park, Guillermo Scaglia

Faculty Publications

Nitrogen (N) fertilizer management in agricultural field affects soil N budget that can have significant implication in greenhouse gas emission and environmental pollution. This study investigates the effects of nitrification inhibitors Dicyandiamide (DCD) and 3,4-dimethyl pyrazole phosphate (DMPP) with urea application on soil N budget and microbial community in a subtropical pasture field. A field experiment consisting of four treatments, including control, urea, urea DCD, and urea DMPP was conducted in 2016 and 2017. Nitrous oxide emission and inorganic-N losses through leaching and runoff were quantified. In addition, soil microbial community response to the imposed treatments was characterized by analysis …

A Theoretical Calculation Of Stacking Fault Energy Of Ni Alloys: The Effects Of Temperature And Composition, Mohammad S. Dodaran, Shengmin Guo, Michael M. Khonsari, Nima Shamsaei, Shuai Shao

Faculty Publications

Combining cluster expansion (CE) method with one dimensional axial Ising model, this work investigated the effects of alloying elements and configurational variations due to temperature on the stacking fault energy (SFE) of FCC Ni binary alloys. Ensembles of large numbers of atomistic structures, each with more than ~400 atoms, were generated to consider sufficient long-range chemical disorder and temperature effects due to configurational entropy. A Monte Carlo Metropolis algorithm was used to generate these structures, whose energies were then evaluated based on the effective cluster interactions obtained from CE. As a baseline, this work had shown the SFE of pure …

Trichoderma Asperellum Inoculation As A Tool For Attenuating Drought Stress In Sugarcane, Daniele Scudeletti, Carlos Alexandre Costa Crusciol, João William Bossolani, Luiz Gustavo Moretti, Letusa Momesso, Brenda Servaz Tubaña, Sérgio Gustavo Quassi De Castro, Elisa Fidêncio De Oliveira, Mariangela Hungria

Faculty Publications

Drought stress is an important concern worldwide which reduces crop yield and quality. To alleviate this problem, Trichoderma asperellum has been used as a plant growth-promoting fungus capable of inducing plant tolerance to biotic and abiotic stresses. Here, we examined the effect of T. asperellum inoculation on sugarcane plant above and belowground development under drought stress and investigated the role of this fungus on inducing tolerance to drought at physiological and biochemical levels. The experiment was performed in pots under greenhouse conditions, with four treatments and four replicates. The treatments consisted of sugarcane plants inoculated or not with T. asperellum …

High Temperature Polymer Electrolytes For Hydrogen Fuel Cells And Electrochemical Pumps, Gokul Venugopalan

LSU Doctoral Dissertations

Hydrogen fuel cell and separation technologies such as proton exchange membrane fuel cells (PEMFCs) and electrochemical hydrogen pump (ECHP) offer a profound advantage in the transition to a low-carbon economy. An imperative hitch in hydrogen fuel cells and ECHP technology has been the electrocatalyst poisoning by carbon monoxide (CO) and other contaminants in the reactant mixture. By operating, hydrogen fuel cells and ECHPs at high temperatures (>200 °C), the effect of CO adsorption on the electrocatalyst surface could be curtailed. The high-temperature operation of devices necessitates a proton exchange membrane (PEM) to operate under anhydrous conditions.

In this work, …

Machine Learning Approach To Pattern Recognition In Nuclear Dynamics From The Ab Initio Symmetry-Adapted No-Core Shell Model, Oleksandr Molchanov

Honors Capstones

No abstract provided.

A Genetic Screen Identifies New Steps In Oocyte Maturation That Enhance Proteostasis In The Immortal Germ Lineage, M Samaddar, J Goudeau, M Sanchez, D H. Hall, M Samaddar, M Ingaramo, C Kenyon

Faculty Publications

Somatic cells age and die, but the germ-cell lineage is immortal. In Caenorhabditis elegans, germline immortality involves proteostasis renewal at the beginning of each new generation, when oocyte maturation signals from sperm trigger the clearance of carbonylated proteins and protein aggregates. Here, we explore the cell biology of this proteostasis renewal in the context of a whole-genome RNAi screen. Oocyte maturation signals are known to trigger protein-aggregate removal via lysosome acidification. Our findings suggest that lysosomes are acidified as a consequence of changes in endoplasmic reticulum activity that permit assembly of the lysosomal V-ATPase, which in turn allows lysosomes to …

Capture And Metabolomic Analysis Of The Human Endometrial Epithelial Organoid Secretome, Constantine A. Simintiras, Pramod Dhakal, Chaman Ranjit, Harriet C. Fitzgerald, Ahmed Z. Balboula, Thomas E. Spencer

Faculty Publications

Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes to offspring susceptibility to chronic adult-onset disorders. However, our understanding of the biochemical composition and mechanisms underpinning UF formation and regulation remain elusive, particularly in humans. To address this challenge, we developed a high-throughput method for intraorganoid fluid (IOF) isolation from human endometrial epithelial organoids. The IOF is biochemically distinct to the extraorganoid fluid (EOF) and cell culture medium as evidenced by the exclusive presence of 17 metabolites in IOF. Similarly, 69 metabolites were unique to EOF, showing asymmetrical apical and basolateral secretion by the in vitro …

Gastrointestinal Microenvironment And The Gut-Lung Axis In The Immune Responses Of Severe Covid-19, Yun Yang, Weishan Huang, Yubo Fan, Guo-Qiang Chen

Faculty Publications

The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented threat to the human health. A close association of the digestive tract is implied by the high frequency of gastrointestinal syndromes among COVID-19 patients. A better understanding of the role of intestinal microenvironment in COVID-19 immunopathology will be helpful to improve the control of COVID-19 associated morbidity and mortality. This review summarizes the immune responses associated with the severity of COVID-19, the current evidence of SARS-CoV-2 intestinal tropism, and the potential involvement of gut microenvironment in COVID-19 severity. Additionally, we …

Physicochemical Properties Of High Protein Rice Flours And Application In A Cupcake, Ricardo Jose Santos Aleman

LSU Master's Theses

Rice (Oryza sativa L.) is an important ingredient for the development of gluten free bakery products. The quality of these types of products varies depending on the levels of rice amylose, particle size of the rice flour, grain length, water absorption rate and the used of other ingredients such as hydrocoillds. This research work aimed to develop a cupcake using high protein brown rice flour in combination with tapioca starch and potato starch of which the formulations were evaluated for textural properties (resilience, springiness, chewiness, cohesiveness and hardness), specific volume, color and sensory attributes, using a mixture design of Simplex-Centroid …

Evaluation Of Vertical And Horizontal Wells For Utilization In Carbon Sequestration, Michael R. Bohnet

Honors Capstones

No abstract provided.

Structure-Activity Relationship Analysis Of Psychedelics In A Rat Model Of Asthma Reveals The Anti-Inflammatory Pharmacophore, Thomas W. Flanagan, Gerald B. Billac, Alexus N. Landry, Melaine N. Sebastian, Stephania A. Cormier, Charles D. Nichols

Division of Basic Science Faculty Publications

Psychedelic drugs can exert potent anti-inflammatory effects. However, anti-inflammatory effects do not appear to correlate with behavioral activity, suggesting different underlying mechanisms. We hypothesized that the distinct structural features of psychedelics underlie functionally selective mechanisms at the target 5-HT2A receptor to elicit maximal anti-inflammatory effects. In order to test this hypothesis, we developed a new rat-based screening platform for allergic asthma. Next, we investigated 21 agonists at the 5-HT2A receptor from the three primary chemotypes (phenylalkylamine, ergoline, and tryptamine) for their ability to prevent airways hyperresponsiveness as a measure of pulmonary inflammation. Furthermore, we assessed each drug for in vitro …

Anesthetic Combination Of Alfaxalone, Dexmedetomidine And Hydromorphone For Comparison Of Endoscopy-Guided Intubation And Blind Orotracheal Intubation In Domestic Rabbits (Oryctolagus Cuniculus), Stephanie Reabel

LSU Master's Theses

Domestic rabbits have a high risk of anesthesia-related mortality compared to other companion animals. Factors that may contribute to increased mortality include drug-induced cardiopulmonary effects (Grint & Murison 2008; Navarrete-Calvo et al. 2013), difficulty performing intubation (Aeschbacher 1995; Flecknell 2016; Wenger et al. 2017) or damage to laryngeal and tracheal tissues following orotracheal intubation (Grint et al. 2006; Phaneuf et al. 2006; Engbers et al. 2017).

Alfaxalone is a neuroactive steroid that produces induction of anesthesia and cardiorespiratory depression in a dose-dependent manner when injected intravenously. The ability to induce anesthesia via an intramuscular (IM) route has several advantages in …

The Second Line Parade And The Construction Of Identity Through Costume In The Group The Undefeated Divas, Gents And Kids., Suellen Da Costa Coelho

LSU Master's Theses

This research aims to investigate the role of costume in identity formation in the second line group The Undefeated Divas, Gents and Kids. The methodology used in this research was data collection through interviews with members of the group. Through these interviews, we seek to establish the importance of costume in reflecting and constructing a sense of community within the group.

While the existing literature focuses on the history of second line parades and their importance in Louisiana’s culture, this research intends to explore costume’s meaning and significance. The purpose of this work is to complement the existing literature in …

Irrigation-Intensive Groundwater Modeling Of Complex Aquifer Systems Through Integration Of Big Geological Data, Hamid Vahdat-Aboueshagh, Frank T.C. Tsai, Dependra Bhatta, Krishna P. Paudel

Faculty Publications

This study identifies hydrogeologic characteristics of complex aquifers based on constructing stratigraphic structure with large, non-uniform well log data. The approach was validated through a modeling study of the irrigation-intensive Chicot aquifer system, which is an important Pleistocene-Holocene aquifer of the Coastal Lowlands aquifer system in the southwestern Louisiana. Various well log types were unified into the same data structure, prioritized based on data sources, and interpolated to generate a detailed stratigraphic structure. More than 29,000 well logs were integrated to construct a stratigraphy model of 56 model layers for the Chicot aquifer system. The stratigraphy model revealed interconnections of …

Aspire To Inspire: A Mentoring Program's Efforts To Inspire Disconnected African American Male Students To Aspire To Their Goals., Khristopher Keon Hobbs

LSU Doctoral Dissertations

ABSTRACT

This study was designed to explore, record, explain and describe the lived experiences of African American male students engaged in mentorship programs for post-secondary education. This study takes an exploratory phenomenological approach to research and is conducted at a mentorship program site. The following research questions guided this study and provided insight into participant’s experiences:

1. How do Black males describe their experience in a holistic mentorship development program that prepares them for post-secondary educational success?
2. How were aspirations for post-secondary education cultivated among Black male students who are currently enrolled in high school and entering their first year in …

Development Of Pudding And Gravy With Rice Starch, Stearic Acid And Lysine, Andrea Suazo Rosales

LSU Master's Theses

Starch is a common ingredient used in the food industry for many products. This study was focused on developing products (gravy and pudding) with a clean label starch. The clean label starch was prepared with rice starch, 1% stearic acid, and 6% lysine, which was gelatinized, freeze-dried, and grinded. Both products were made with three different starch types: rice starch, commercial modified starch, and clean label starch. These starches were analyzed with DSC, SEM, Megazyme Amylose/Amylopectin kit, and RVA. With the results from the RVA, SEM, and DCS it is inferred that the freeze-drying process has altered the structure of …

Effects Of Historical Land-Use Change On Surface Runoff And Flooding In The Amite River Basin, Louisiana, Usa Using Coupled 1d/2d Hec-Ras–Hec-Hms Hydrological Modeling, Alexandre G. H. Cowles

LSU Master's Theses

The Amite River Basin is a largely rural watershed spanning parts of four counties in southern Mississippi and seven parishes in southeast Louisiana, with basinwide imperviousness increasing from 0.82% in 1938 to 3.85% in 2016. The Basin has been the subject of significant research interest since catastrophic flooding in 2016 caused 13 deaths and widespread damages. Rapid development in recent decades has led to an expansion of impervious surfaces in Baton Rouge and surrounding areas, encroaching on floodplains and wetlands. At the basin scale, differences in flooding due to impervious cover changes were found to be somewhat limited, particularly along …