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F21rs Sgcr No. 29 (Nicole Spriggs-Moye, Psif), Taylor Perrodin

Student Senate Enrolled Legislation

A Concurrent Resolution

To appoint Nicole Spriggs-Moye as an executive delegate for the Program Support Initiative Fund Committee

F21rs Sgcr No. 27 (Colin Raby, Psif), Taylor Perrodin

Student Senate Enrolled Legislation

A Concurrent Resolution

To appoint Colin Raby as a Legislative delegate for the Program Support Initiative Fund Committee

Hot Spot Of Ch4 Production And Diffusive Flux In Rivers With High Urbanization, Wei Tang, Y. Jun Xu, Yongmei Ma, Damien T. Maher, Siyue Li

Faculty Publications

Rivers and streams play a central role in global carbon budget, but our knowledge is limited on the magnitude and extent of urbanization influence on riverine methane (CH4) dynamics. In this study, we investigated dissolved CH4 (dCH4) concentration and CH4 diffusive fluxes in 27 river segments of two 4th-order and three 3rd-order tributary rivers to the Yangtze River in China, which drained land areas with varied urbanization intensities. We found that urban development was the key factor responsible for high fluvial dCH4 concentration and diffusive flux, exceeding the influence of agricultural farming, and these headwater rivers were over-saturated in CH4 …

Leptin Receptor Signaling Is Required For Intact Hypoglycemic Counterregulation: A Study In Male Zucker Rats, Christopher D. Morrison, Marina A. Duvall, Cristal M. Hill, Redin A. Spann, David H. Mcdougal

Division of Basic Science Faculty Publications

Hypoglycemia is a major barrier to clinical management of persons with diabetes. Emerging evidence supports a role for leptin in gating hypoglycemic counterregulation. This work demonstrates that male leptin receptor null, Zucker (fa/fa), rats display severe impairments in hypoglycemic counterregulation. Thus, augmenting leptin levels may have clinical utility for preventing hypoglycemia.

Nest Survival Of Seaside Sparrows (Ammospiza Maritima) In The Wake Of The Deepwater Horizon Oil Spill, Megan E. Hart, Anna Perez-Umphrey, Philip C. Stouffer, Christine Bergeon Burns, Andrea Bonisoli-Alquati, Sabrina S. Taylor, Stefan Woltmann

Faculty Publications

In 2010, the Deepwater Horizon oil spill released an estimated 4.9 million barrels of oil into the Gulf of Mexico, damaging coastal ecosystems. Seaside Sparrows (Ammospiza maritima)—a year-round resident of Gulf Coast salt marshes—were exposed to oil, as shown by published isotopic and molecular analyses, but fitness consequences have not been clarified. We monitored nests around two bays in Plaquemines Parish, Louisiana, USA from 2012–2017 to assess possible impacts on the nesting biology of Seaside Sparrows. A majority of nests failed (76% of known-fate nests, N = 252 nests, 3521 exposure-days) during our study, and predation was the main cause …

Effect Of Aerobic Exercise-Induced Weight Loss On The Components Of Daily Energy Expenditure, Nicholas T. Broskey, Corby K. Martin, Jeffrey H. Burton, Timothy S. Church, Eric Ravussin, Leanne M. Redman

Clinical Research Faculty Publications

Introduction Exercise usually results in less weight loss than expected. This suggests increased energy intake and/or deceased expenditure counteract the energy deficit induced by exercise. The aim of this study was to evaluate changes in components of daily energy expenditure (doubly labeled water and room calorimetry) after 24 wk of exercise training with two doses of aerobic exercise. Methods This was an ancillary study in 42 (29 women, 13 men) sedentary, middle-age (47.8 ± 12.5 yr) individuals with obesity (35 ± 3.7 kg·m-2) enrolled in the Examination of Mechanisms of Exercise-induced Weight Compensation study. Subjects were randomized to three groups: …

Effect Of 2-Year Caloric Restriction On Organ And Tissue Size In Nonobese 21- To 50-Year-Old Adults In A Randomized Clinical Trial- To Calerie Study, Wei Shen, Jun Chen, Jane Zhou, Corby K. Martin, Eric Ravussin, Leanne M. Redman

Clinical Research Faculty Publications

Background: Sustained calorie restriction (CR) promises to extend the lifespan. The effect of CR on changes in body mass across tissues and organs is unclear. Objectives: We used whole-body MRI to evaluate the effect of 2 y of CR on changes in body composition. Methods: In an ancillary study of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, 43 healthy adults [25-50 y; BMI (kg/m2): 22-28] randomly assigned to 25% CR (n = 28) or ad libitum (AL) eating (n = 15) underwent whole-body MRI at baseline and month 24 to measure adipose tissue in …

Analysis Of A New Multispecies Tumor Growth Model Coupling 3d Phase-Fields With A 1d Vascular Network, Marvin Fritz, Prashant K. Jha, Tobias Köppl, J. Tinsley Oden, Barbara Wohlmuth

Faculty Publications

In this work, we present and analyze a mathematical model for tumor growth incorporating ECM erosion, interstitial flow, and the effect of vascular flow and nutrient transport. The model is of phase-field or diffused-interface type in which multiple phases of cell species and other constituents are separated by smooth evolving interfaces. The model involves a mesoscale version of Darcy's law to capture the flow mechanism in the tissue matrix. Modeling flow and transport processes in the vasculature supplying the healthy and cancerous tissue, one-dimensional (1D) equations are considered. Since the models governing the transport and flow processes are defined together …

Modeling And Simulation Of Vascular Tumors Embedded In Evolving Capillary Networks, Marvin Fritz, Prashant K. Jha, Tobias Köppl, J. Tinsley Oden, Andreas Wagner, Barbara Wohlmuth

Faculty Publications

In this work, we present a coupled 3D–1D model of solid tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes erosion of the extracellular matrix, interstitial flow, and coupled flow in blood vessels and tissue. We employ continuum mixture theory with stochastic Cahn–Hilliard type phase-field models of tumor growth. The interstitial flow is governed by a mesoscale version of Darcy's law. The flow in the blood vessels is controlled by Poiseuille flow, and Starling's law is applied to model the mass transfer in and out of blood vessels. The evolution of …

Foregut Exclusion Enhances Incretin And Insulin Secretion After Roux-En-Y Gastric Bypass In Adults With Type 2 Diabetes, John P. Kirwan, Christopher L. Axelrod, Emily L. Kullman, Steven K. Malin, Wagner S. Dantas, Kathryn Pergola, Juan Pablo Del Rincon, Stacy A. Brethauer, Sangeeta R. Kashyap, Philip R. Schauer

Division of Basic Science Faculty Publications

Introduction: Patients with type 2 diabetes experience resolution of hyperglycemia within days after Roux-en-Y gastric bypass (RYGB) surgery.This is attributed, in part, to enhanced secretion of hindgut factors following exclusion of the gastric remnant and proximal intestine during surgery. However, evidence of the mechanisms of remission remain limited due to the challenges of metabolic evaluation during the early postoperative period. The purpose of this investigation was to determine the role of foregut exclusion in the resolution of type 2 diabetes after RYGB. Methods: Patients with type 2 diabetes (n = 15) undergoing RYGB had a gastrostomy tube (G-tube) placed in …

Dynamin-Related Protein 1 Regulates Substrate Oxidation In Skeletal Muscle By Stabilizing Cellular And Mitochondrial Calcium Dynamics, William T. King, Christopher L. Axelrod, Elizabeth R.M. Zunica, Robert C. Noland, Gangarao Davuluri, Hisashi Fujioka, Bernard Tandler, Kathryn Pergola, Gerlinda E. Hermann, Richard C. Rogers, Sandra López-Domènech, Wagner S. Dantas, Krisztian Stadler, Charles L. Hoppel, John P. Kirwan

Division of Basic Science Faculty Publications

Mitochondria undergo continuous cycles of fission and fusion to promote inheritance, regulate quality control, and mitigate organelle stress. More recently, this process of mitochondrial dynamics has been demonstrated to be highly sensitive to nutrient supply, ultimately conferring bioenergetic plasticity to the organelle. However, whether regulators of mitochondrial dynamics play a causative role in nutrient regulation remains unclear. In this study, we generated a cellular loss-of-function model for dynamin-related protein 1 (DRP1), the primary regulator of outer membrane mitochondrial fission. Loss of DRP1 (shDRP1) resulted in extensive ultrastructural and functional remodeling of mitochondria, characterized by pleomorphic enlargement, increased electron density of …

Practical Application Of In Vivo Mri-Based Brown Adipose Tissue Measurements In Infants, Emily W. Flanagan, Abby D. Altazan, Owen T. Carmichael, Houchun H. Hu, Leanne M. Redman

Clinical Research Faculty Publications

Objective: The role of brown adipose tissue (BAT) in infant metabolism remains poorly understood, primarily because of the inherent limitation of positron emission tomography/computed tomography imaging to measure BAT, which is not suitable for infants. The aims of this method development study were to assess the feasibility, intra-rater reliability, interscan repeatability, and physiological relevance of measuring BAT in infants using magnetic resonance imaging (MRI). Methods: A total of 10 nonsedated infants (mean age, 22.6 [1.3] days old) completed two 3-T MRI exams using chemical-shift-encoded water-fat scans 6.2 (2.8) days apart. Candidate BAT voxels in the supraclavicular region were identified based …

Legacy Of A 10-Year Multidomain Lifestyle Intervention On The Cognitive Trajectories Of Individuals With Overweight/Obesity And Type 2 Diabetes Mellitus, Kathleen M. Hayden, Rebecca H. Neiberg, Joni K. Evans, José A. Luchsinger, Owen Carmichael, Gareth R. Dutton, Karen C. Johnson, Steven E. Kahn, Stephen R. Rapp, Sevil Yasar, Mark A. Espeland

Clinical Research Faculty Publications

Introduction: Weight loss and increased physical activity interventions are commonly recommended for individuals with type 2 diabetes (T2D) and overweight or obesity. We examined the impact of randomization to an intensive lifestyle intervention (ILI) on trajectories of cognitive function over 10 years in a cohort of participants in a randomized clinical trial who had T2D and overweight/obesity at baseline. Methods: Participants aged 45-76 years were enrolled in 2001-2004 and were randomized to the ILI or a diabetes support and education (DSE) condition. Cognitive function was assessed in 3,938 participants at up to 4 time points 8-18 years after randomization. General …

Carcass Yields And Physical-Chemical Meat Quality Characteristics Of Namibian Red Hartebeest (Alcelaphus Buselaphus) As Influenced By Sex And Muscle, Louwrens C. Hoffman, Diana L. Van Schalkwyk, Magdalena Muller, Tersia Needham, Kenneth W. Mcmillin

Faculty Publications

This study determined the carcass yields of red hartebeest from Namibia and compared the physical-chemical meat quality characteristics of six different muscles (biceps femoris, infraspinatus, longissimus thoracis et lumborum, semimembranosus, semitendinosus, and supraspinatus) for both males and females. Red hartebeest males were heavier (133.92 kg) than females (114.20 kg) but the average dressing percentage did not differ between the two sexes. Muscles from females had a lower mean shear force value of 3.59 kg/1.27 cm ø, compared to males (4.23 kg/1.27 cm ø). The most tender muscle was the infraspinatus of the female treatment group, while the semimembranosus of the …

Effect Of Federal Inspection On Louisiana Wild-Caught Catfish Industry, Prevalence Of Salmonella, And Microbial Characteristics Of Raw Wild-Caught Catfish Fillets, Katheryn Parraga, Silvia Murillo, Cesar Escalante, Evelyn Watts

Faculty Publications

The United States is one of the largest catfish producers in the world. Louisiana is the leading producer of wild-caught catfish. Historically, the U.S. Food and Drug Administration inspected all seafood products; however, in 2008, Congress moved the inspection of fish in the order Siluriformes to the U.S. Department of Agriculture (USDA), Food Safety and Inspection Service. Full enforcement of the rule began on 1 September 2017. The present study was conducted to assess the impact of USDA Siluriformes fish regulation on small Louisiana wild-caught catfish processors and to determine the microbiological quality of and Salmonella prevalence in raw fillets. …

X-Ray Observations Of Two Candidate Symbiotic Binaries In The Galactic Bulge, Joshua Wetuski, R. I. Hynes, T. J. Maccarone, C. Heinke, M. A.P. Torres, P. G. Jonker, Christopher T. Britt, D. Steeghs, G. Nelemans

Faculty Publications

This paper analyses X-ray observations by the Chandra X-ray Observatory of CXOGBS J174614.3-321949 (CXB3) and CXOGBS J173620.2-293338 (CX332), two symbiotic binary star candidates identified by the Galactic Bulge Survey. Using new Chandra observations, we improved their X-ray positional uncertainties to 0.24 and 0.92 arcsec, respectively, confidently associating them with single optical counterparts. In particular, new observations of symbiotic X-ray candidate CX332 further solidify confidence in its coincidence with a carbon star. We demonstrate X-ray variability in both targets with a more recent observation of CX332 showing a decrease in brightness by a factor of 30, while CXB3 observations show it …

A Polynomial Roth Theorem For Corners In Finite Fields, Rui Han, Michael T. Lacey, Fan Yang

Faculty Publications

We prove a Roth-type theorem for polynomial corners in the finite field setting. Let ϕ1 and ϕ2 be two polynomials of distinct degree. For sufficiently large primes p, any subset (Formula presented.) with (Formula presented.) contains three points (Formula presented.). The study of these questions on (Formula presented.) was started by Bourgain and Chang. Our Theorem adapts the argument of Dong, Li, and Sawin, in particular relying upon deep Weil-type inequalities established by N. Katz.

Experimental Study Of The Nature Of The And Excited States In Using The Reaction In Inverse Kinematics, K. Kuhn, F. Sarazin, F. M. Nunes, M. A.G. Alvarez, C. Andreoiu, D. W. Bardayan, P. C. Bender, J. C. Blackmon, M. J.G. Borge, R. Braid, B. A. Brown, W. N. Catford, C. Aa Diget, A. Dipietro, T. E. Drake, P. Figuera, A. B. Garnsworthy, J. Gómez-Camacho, G. Hackman, U. Hager, S. V. Ilyushkin, E. Nácher, P. D. O'Malley, A. Perea, V. Pesudo, S. T. Pittman, D. Smalley, C. E. Svensson, O. Tengblad, P. Thompson, C. Unsworth, Z. M. Wang

Faculty Publications

The nature of the and excited states in is studied using the transfer reaction in inverse kinematics at 10A MeV at TRIUMF ISAC-II, in particular to assess whether either of them can be considered as an excited halo state. The angular distributions for both states are extracted using deuteron- coincidences and analyzed using a transfer model taking into account one-step and two-step processes. A good fit of the angular distributions is obtained considering only the one-step process, whereby an inner neutron of is removed, leaving the halo neutron intact. Higher-order processes however cannot be rejected. The small spectroscopic factors extracted …

Random Matrix Theory In Cd Isotopes, A. J. Majarshin, Yan An Luo, Feng Pan, Jerry P. Draayer

Faculty Publications

Random matrix theory (RMT) is used to provide a measure of the chaoticity (q) of calculated results for the spectra for various Cd isotopes. The goal is to gain a better understanding of the internal dynamics in play; namely, whether it tracks with regular or irregular (chaotic) behavior as determined through an RMT analyses of calculated spectra. The basis-state configurations used to determine the spectra includes all positive, negative, natural (J π = 1-, 2+, ...), and unnatural parity configurations (J π = 0-, 1+, 2-, ...), unless suppressed for comparative purposes. The results show that when intruder-state configurations are …

Exact Solution Of The Two-Axis Two-Spin Hamiltonian, Feng Pan, Yao Zhong Zhang, Xiaohan Qi, Yue Liang, Yuqing Zhang, Jerry P. Draayer

Faculty Publications

Bethe ansatz solution of the two-axis two-spin Hamiltonian is derived based on the Jordan-Schwinger boson realization of the SU(2) algebra. It is shown that the solution of the Bethe ansatz equations can be obtained as zeros of the related extended Heine-Stieltjes polynomials. Symmetry properties of excited levels of the system and zeros of the related extended Heine-Stieltjes polynomials are discussed. As an example of an application of the theory, the two equal spin case is studied in detail, which demonstrates that the levels in each band are symmetric with respect to the zero energy plane perpendicular to the level diagram …

Increases In Adiposity Among Children And Adolescents Over Time: Moving Beyond Bmi, Amanda E. Staiano, Peter T. Katzmarzyk

Population and Public Health Science Faculty Publications

No abstract provided.

Ehealth Interventions Targeting Nutrition, Physical Activity, Sedentary Behavior, Or Obesity In Adults: A Scoping Review Of Systematic Reviews, Melinda J. Hutchesson, Claire Gough, Andre Matthias Müller, Camille E. Short, Megan C. Whatnall, Mavra Ahmed, Nicole Pearson, Zenong Yin, Lee M. Ashton, Carol Maher, Amanda E. Staiano, Chelsea E. Mauch, Ann Desmet, Corneel Vandelanotte

Population and Public Health Science Faculty Publications

A vast body of evidence regarding eHealth interventions for nutrition, physical activity, sedentary behavior, and obesity exists. This scoping review of systematic reviews aimed to evaluate the current level of evidence in this growing field. Seven electronic databases were searched for systematic reviews published until October 27, 2019. The systematic reviews must have included adult participants only and have evaluated eHealth behavioral interventions with the primary aim of changing nutrition, physical activity, and sedentary behavior or treating or preventing overweight and obesity. One hundred and six systematic reviews, published from 2006 to 2019, were included. Almost all (n = 98) …

The Inverse Problem For A Spectral Asymmetry Function Of The Schrödinger Operator On A Finite Interval, B. Malcolm Brown, Karl Michael Schmidt, Stephen P. Shipman, Ian Wood

Faculty Publications

For the Schrödinger equation (Formula presented.) on a finite x-interval, there is defined an “asymmetry function” (Formula presented.), which is entire of order 1/2 and type 1 in λ. Our main result identifies the classes of square-integrable potentials (Formula presented.) that possess a common asymmetry function (Formula presented.). For any given (Formula presented.), there is one potential for each Dirichlet spectral sequence.

On The Genetic Architecture In A Public Tropical Maize Panel Of The Symbiosis Between Corn And Plant Growth-Promoting Bacteria Aiming To Improve Plant Resilience, Rafael Massahiro Yassue, Humberto Fanelli Carvalho, Raysa Gevartosky, Felipe Sabadin, Pedro Henrique Souza, Maria Leticia Bonatelli, João Lúcio Azevedo, Maria Carolina Quecine, Roberto Fritsche-Neto

Faculty Publications

Exploring the symbiosis between plants and plant growth-promoting bacteria (PGPB) is a new challenge for sustainable agriculture. Even though many works have reported the beneficial effects of PGPB in increasing plant resilience for several stresses, its potential is not yet widely explored. One of the many reasons is the differential symbiosis performance depending on the host genotype. This opens doors to plant breeding programs to explore the genetic variability and develop new cultivars with higher responses to PGPB interaction and, therefore, have higher resilience to stress. Hence, we aimed to study the genetic architecture of the symbiosis between PGPB and …

Insights Into The Tectonostratigraphic Setting Of The Southern Appalachians During The Blountian Tectophase From An Integrated Geochemical Analysis Of Magmatic Phenocrysts In The Ordovician Deicke K-Bentonite, Achim D. Herrmann, John T. Haynes, Richard M. Robinet, Jürgen Konzett, Norlene R. Emerson

Faculty Publications

We evaluate competing hypotheses regarding tectonic models of the early Taconic Orogeny in the Southern Appalachians during the Blountian tectophase with new geochemical data obtained from analyses of apatite and zircon phenocrysts, and melt and mineral inclusions therein, from the Ordovician Deicke K-bentonite (453.35 ± 0.10 Ma). Apatite geochemistry confirms that samples from different locations represent the same eruptive event, and zircon geochemistry and U[sbnd]Pb geochronology (including several Grenville-age inherited detrital cores) confirm an evolved magma of continental-arc composition, with the trace-metal geochemistry of magmatic Taconic-age rims on Deicke zircons pointing to a provenance of continental crustal igneous rock melts, …

Atlas Of Receptor Genes Expressed By The Bovine Morula And Corresponding Ligand-Related Genes Expressed By Uterine Endometrium, Lei Sang, Yao Xiao, Zongliang Jiang, Niamh Forde, Xiuchun Cindy Tian, Patrick Lonergan, Peter J. Hansen

Faculty Publications

Regulation of the mammalian embryo involves cell-signaling molecules produced by the maternal oviduct and endometrium. Here, datasets on the transcriptome of the gestational Days 5 and 6 bovine morula and Day 5 maternal endometrium were examined to identify receptor genes expressed by the morula and expression of the corresponding ligand-related genes in the endometrium. A total of 175 receptor genes were identified in the morula, including 48 encoding for growth factors or WNT signaling molecules, 25 for cytokines and chemokines, 35 involved in juxtacrine and matricellular signaling and 25 encoding for receptors for small molecules. Some of the highly-expressed pairs …

More Vigorous Efforts Are Needed To Fight Obesity, A Serious Public Health Problem In China, Gang Hu

Population and Public Health Science Faculty Publications

No abstract provided.

Bulk Scanning Method Of A Heavy Metal Concentration In Tailings Of A Gold Mine Using Swir Hyperspectral Imaging System, Yongsik Jeong, Jaehyung Yu, Lei Wang, Kwang Jae Lee

Faculty Publications

This work introduces a bulk data acquisition method using a hyperspectral imaging system (HIS) to measure chromium (Cr) concentration in the soil samples obtained from tailings of a gold mine considering of the spectral competition between heavy metal elements. The chemical, mineralogical, and spectroscopic analyses in a laboratory environment revealed that heavy metal elements' competitive geochemical behaviors were manifested as spectral competitions between heavy metal elements in tailings. The heavy metal elements can be classified into two groups based on their geochemical behaviors: chromium-nickel (Cr-Ni) and zinc-arsenic-cadmium-lead (Zn-As-Cd-Pb). We found an inverse relationship between the two groups in their spectral …

Preference, Expected Burden, And Willingness To Use Digital And Traditional Methods To Assess Food And Alcohol Intake, Christoph Höchsmann, Nicole Fearnbach, James L. Dorling, Tera L. Fazzino, Candice A. Myers, John W. Apolzan, Corby K. Martin

Clinical Research Faculty Publications

We conducted an online survey to examine the preference, expected burden, and willingness of people to use four different methods of assessing food and alcohol intake such as food/drink record, 24-h recall, Remote Food Photography Method© (RFPM, via SmartIntake® app), and a novel app (PortionSize® ) that allows the in-app portion size estimation of foods/drinks by the user. For food (N = 1959) and alcohol (N = 466) intake assessment, 67.3% and 63.3%, respectively, preferred the RFPM/SmartIntake®, 51.9% and 53.4% preferred PortionSize®, 48.0% and 49.3% the food records, and 32.9% and 33.9% the 24-h recalls (difference in preference across all …

Consensus Revisited: Quantifying Scientific Agreement On Climate Change And Climate Expertise Among Earth Scientists 10 Years Later, Krista F. Myers, Peter T. Doran, John Cook, John E. Kotcher, Teresa A. Myers

Faculty Publications

The scientific consensus on human-caused global warming has been a topic of intense interest in recent decades. This is in part due to the important role of public perception of expert consensus, which has downstream impacts on public opinion and support for mitigation policies. Numerous studies, using diverse methodologies and measures of climate expertise, have quantified the scientific consensus, finding between 90% and 100% agreement on human-caused global warming with multiple studies converging on 97% agreement. This study revisits the consensus among geoscientists ten years after an initial survey of experts, while exploring different ways to define expertise and the …