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Bioelectrical Impedance Phase Angle Is Associated With Physical Performance Before But Not After Simulated Multi-Stressor Military Operations, Alyssa N. Varanoske, Melissa N. Harris, Callie Hebert, Neil M. Johannsen, Steven B. Heymsfield, Frank L. Greenway, Arny A. Ferrando, Jennifer C. Rood, Stefan M. Pasiakos Mar 2023

Bioelectrical Impedance Phase Angle Is Associated With Physical Performance Before But Not After Simulated Multi-Stressor Military Operations, Alyssa N. Varanoske, Melissa N. Harris, Callie Hebert, Neil M. Johannsen, Steven B. Heymsfield, Frank L. Greenway, Arny A. Ferrando, Jennifer C. Rood, Stefan M. Pasiakos

Clinical Research Faculty Publications

Physical performance decrements observed during multi-stressor military operations may be attributed, in part, to cellular membrane dysfunction, which is quantifiable using phase angle (PhA) derived from bioelectrical impedance analysis (BIA). Positive relationships between PhA and performance have been previously reported in cross-sectional studies and following longitudinal exercise training programs, but whether changes in PhA are indicative of acute decrements in performance during military operations is unknown. Data from the Optimizing Performance for Soldiers II study, a clinical trial examining the effects of exogenous testosterone administration on body composition and performance during military stress, was used to evaluate changes in PhA …


Factors Influencing Consumers’ Willingness-To-Try Seafood Byproducts, Silvia Murillo, Ryan Ardoin, Witoon Prinyawiwatkul Mar 2023

Factors Influencing Consumers’ Willingness-To-Try Seafood Byproducts, Silvia Murillo, Ryan Ardoin, Witoon Prinyawiwatkul

Faculty Publications

With increasing global demand for seafood, seafood byproducts (SB) utilization can contribute to a more sustainable food supply chain through waste-to-value food product development. However, consumer perceptions of SB (e.g., fish skin and bones) are underexplored. Therefore, this study aims to evaluate some factors influencing consumers’ willingness-to-try seafood byproducts. An online survey was conducted in the USA regarding intervention of SB informational cues with N = 904 adult seafood consumers internationally. The proportion of consumers willing to try SB increased significantly (McNemar’s test, α = 0.05) from 47% to 68% after SB safety and health claims had been presented in …


Florawear: Wearable Living Interface, Hye Yeon Nam, Janiece Campbell, Andrew M. Webb, Brendan Harmon Feb 2023

Florawear: Wearable Living Interface, Hye Yeon Nam, Janiece Campbell, Andrew M. Webb, Brendan Harmon

Faculty Publications

While nature can benefit people both mentally and physically, contemporary society has become increasingly disconnected from nature. To rebuild a stronger connection with nature in our everyday life, we introduce FloraWear, a do-it-yourself, wearable living interface, that enables people to easily and closely connect with plants. This pictorial introduces how knowledge is built and shared with others using hybrid craft and fabrication, illustrates the material experiments and design development for FloraWear, and discusses how it affects wearers. Then we summarize how FloraWear can help catalyze a shift in people's perspectives towards nature. By developing emotional ties to their wearable plants, …


Gamerfit-Asd Beta Test: Adapting An Evidence-Based Exergaming And Telehealth Coaching Intervention For Autistic Youth, Daniel P. Hatfield, Aviva Must, Winston Kennedy, Amanda E. Staiano, James Slavet, Rachael A. Sabelli, Carol Curtin, Linda G. Bandini, Phillip Nauta, Christopher Stuetzle, April B. Bowling Feb 2023

Gamerfit-Asd Beta Test: Adapting An Evidence-Based Exergaming And Telehealth Coaching Intervention For Autistic Youth, Daniel P. Hatfield, Aviva Must, Winston Kennedy, Amanda E. Staiano, James Slavet, Rachael A. Sabelli, Carol Curtin, Linda G. Bandini, Phillip Nauta, Christopher Stuetzle, April B. Bowling

Population and Public Health Science Faculty Publications

Background: Health disparities faced by autistic youth are exacerbated by inadequate physical activity (PA) and sleep, whereas healthy PA and sleep may improve mood and function. Adaptive Game Squad (AGS) is an evidence-based telehealth coaching and exergaming intervention to improve PA and sleep for adolescents with diverse neurodevelopmental and psychiatric conditions. This study aimed to adapt AGS for autistic youth ages 10–15 years; beta-test the modified intervention for feasibility, accessibility, and engagement; and further refine the intervention for a larger planned demonstration pilot. Methods: Interdisciplinary experts adapted AGS to create GamerFit-ASD, a 12-week intervention that included a progressive exergame schedule, …


Effects Of Neighborhood Disadvantage And Peer Deviance On Conduct Problems: Interactions With Age Of Onset, Courtney Marie Goetz Feb 2023

Effects Of Neighborhood Disadvantage And Peer Deviance On Conduct Problems: Interactions With Age Of Onset, Courtney Marie Goetz

LSU Master's Theses

Youth with conduct problems (CP) generally fall into two developmental classifications, child-onset and adolescent-onset, which exhibit different causal processes and life course trajectories. Research suggests that child-onset CP is more likely to be related to individual predispositions, while adolescent-onset CP is more associated with social factors, such as peer delinquency. Living in impoverished and disorganized neighborhoods increases the risk for associating with deviant peers. Thus, the current study tested the hypothesis that neighborhood factors would be more strongly associated with adolescent-onset CP than child-onset CP, which would be explained by a greater association with deviant peers. Linear and negative binomial …


Propaganda Word Counts, Michael Russo Feb 2023

Propaganda Word Counts, Michael Russo

Libraries Datasets

These files are the raw material for a study of the propaganda used by the George W. Bush administration to persuade Americans to support invading Iraq in 2003. They include documents from The Public Papers of the Presidents of the United States, George W. Bush; transcripts of television news shows on ABC, CBS, CNN, FOX, and NBC; and contemporaneous public opinion polling. All documents are from the 9/11/2001 to 3/19/2003 timeframe. Text analysis of the aforementioned documents is also included. The report of conclusions—as yet unpublished—will be found in a paper entitled “The Work of an Hour: A Case Study …


Temporal Features Of Concepts Are Grounded In Time Perception Neural Networks: An Eeg Study, Karim Johari, Vicky T. Lai, Nicholas Riccardi, Rutvik H. Desai Feb 2023

Temporal Features Of Concepts Are Grounded In Time Perception Neural Networks: An Eeg Study, Karim Johari, Vicky T. Lai, Nicholas Riccardi, Rutvik H. Desai

Faculty Publications

Experimental evidence suggests that modality-specific concept features such as action, motion, and sound partially rely on corresponding action/perception neural networks in the human brain. Little is known, however, about time-related features of concepts. We examined whether temporal features of concepts recruit networks that subserve time perception in the brain in an EEG study using event and object nouns. Results showed significantly larger ERPs for event duration vs object size judgments over right parietal electrodes, a region associated with temporal processing. Additionally, alpha/beta (10–15 Hz) neural oscillation showed a stronger desynchronization for event duration compared to object size in the right …


Opioid And Cannabis Co-Use: The Role Of Opioid Use To Cope With Negative Affect, Julia D. Buckner, Caroline R. Scherzer, Andrew H. Rogers, Michael J. Zvolensky Feb 2023

Opioid And Cannabis Co-Use: The Role Of Opioid Use To Cope With Negative Affect, Julia D. Buckner, Caroline R. Scherzer, Andrew H. Rogers, Michael J. Zvolensky

Faculty Publications

Introduction: The opioid epidemic is a significant public health concern, particularly among adults with chronic pain. There are high rates of cannabis co-use among these individuals and co-use is related to worse opioid-related outcomes. Yet, little work has examined mechanisms underlying this relationship. In line with affective processing models of substance use, it is possible that those who use multiple substances do so in a maladaptive attempt to cope with psychological distress. Method: We tested whether, among adults with chronic lower back pain (CLBP), the relation between co-use and more severe opioid-related problems would occur via the serial effects of …


Early Time-Restricted Eating Affects Weight, Metabolic Health, Mood, And Sleep In Adherent Completers: A Secondary Analysis, Felicia L. Steger, Humaira Jamshed, David R. Bryan, Joshua S. Richman, Amy H. Warriner, Cody J. Hanick, Corby K. Martin, Sarah Jeanne Salvy, Courtney M. Peterson Feb 2023

Early Time-Restricted Eating Affects Weight, Metabolic Health, Mood, And Sleep In Adherent Completers: A Secondary Analysis, Felicia L. Steger, Humaira Jamshed, David R. Bryan, Joshua S. Richman, Amy H. Warriner, Cody J. Hanick, Corby K. Martin, Sarah Jeanne Salvy, Courtney M. Peterson

Clinical Research Faculty Publications

Objective: Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed. Methods: Ninety patients aged 25 to 75 years old with obesity were randomized to early TRE (eTRE; 8-hour eating window from 07:00 to 15:00) or a control schedule (≥12-hour window) for 14 weeks. A per-protocol analysis of weight loss, body composition, cardiometabolic health, and other end points was performed. Results: Participants who adhered to eTRE ≥5 d/wk every week had greater improvements in body weight (−3.7 ± 1.2 …


Evaluation Of The Peer Leadership For Physical Literacy Intervention: A Cluster Randomized Controlled Trial, Ryan M. Hulteen, David R. Lubans, Ryan E. Rhodes, Guy Faulkner, Yan Liu, Patti Jean Naylor, Nicole Nathan, Katrina J. Waldhauser, Colin M. Wierts, Mark R. Beauchamp Feb 2023

Evaluation Of The Peer Leadership For Physical Literacy Intervention: A Cluster Randomized Controlled Trial, Ryan M. Hulteen, David R. Lubans, Ryan E. Rhodes, Guy Faulkner, Yan Liu, Patti Jean Naylor, Nicole Nathan, Katrina J. Waldhauser, Colin M. Wierts, Mark R. Beauchamp

Faculty Publications

Purpose The purpose of this research was to develop, implement, and test the efficacy of a theory-driven, evidence-informed peer leadership program for elementary school students (Grade 6 and 7; age 11–12 years) and the Grade 3/4 students with whom they were partnered. The primary outcome was teacher ratings of their Grade 6/7 students’ transformational leadership behaviors. Secondary outcomes included: Grade 6/7 students’ leadership self-efficacy, as well as Grade 3/4 motivation, perceived competence, general self-concept, fundamental movement skills, school-day physical activity, and program adherence, and program evaluation. Methods We conducted a two-arm cluster randomized controlled trial. In 2019, 6 schools comprising …


Finding Forensic Evidence In The Operating System's Graphical User Interface, Edward X. Wilson Mr. Jan 2023

Finding Forensic Evidence In The Operating System's Graphical User Interface, Edward X. Wilson Mr.

LSU Master's Theses

A branch of cyber security known as memory forensics focuses on extracting meaningful evidence from system memory. This analysis is often referred to as volatile memory analysis, and is generally performed on memory captures acquired from target systems. Inside of a memory capture is the complete state of a system under investigation, including the contents of currently running as well as previously executed applications. Analysis of this data can reveal a significant amount of activity that occurred on a system since the last reboot. For this research, the Windows operating system is targeted. In particular, the graphical user interface component …


Media Literacy In Public Education: A Mixed-Method Exploration, Jessica Wyers Jan 2023

Media Literacy In Public Education: A Mixed-Method Exploration, Jessica Wyers

LSU Doctoral Dissertations

You have to know where you are to know where you’re going. This is the approach I attempt to take to understand next steps in media literacy education and policy. Little research has been done to understand the current state of media literacy education, what is actually happening in the classrooms and education system, to better judge more intentional interventions in the future.

This dissertation explores the current issues in media literacy education in our public schools. I combine the strengths of a qualitative investigation of published public school media literacy curricula with survey data measuring the perceptions of students’ …


Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris Jan 2023

Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris

Faculty Publications

Freeboard—elevation of a structure above the base flood elevation (BFE)—is a critical component in mitigating or avoiding flood losses. However, the unrevealed benefits and savings of freeboard installation have prevented communities from adopting this approach. To improve decision-making for residents, prospective residents, and other stakeholders in flood-vulnerable communities and enhance flood risk mitigation strategies, this study presents the methodology underlying a new webtool, FloodSafeHome, that estimates comprehensively the economic benefits and savings of freeboard installation for new construction of residential buildings. Specifically, the proposed evaluation framework has been designed to calculate monthly savings for individual buildings by assessing freeboard cost, …


Factors That Predict Weight Loss Success Differ By Diet Intervention Type, Jordan Losavio, Michael J. Keenan, Elizabeth A. Gollub, Heidi J. Silver Jan 2023

Factors That Predict Weight Loss Success Differ By Diet Intervention Type, Jordan Losavio, Michael J. Keenan, Elizabeth A. Gollub, Heidi J. Silver

Faculty Publications

Background: Many types of diet intervention can achieve negative energy balance and successful weight loss in persons with obesity. However, within any dietary strategy, there is large inter-individual variation in the weight loss response. The aim of this study is to determine factors that predict weight loss success for diet interventions that vary by macronutrient and caloric composition. Methods: Participants with BMI 30.0 to 49.9 kg/m2 self-selected one of three diet intervention trials for weight loss: low carbohydrate (LOW CHO), low fat (LOW FAT), or low calorie (LOW KCAL). Multivariable regression models were developed to determine the significance of predictor …


“By That Daughter’S Most Devoted Affection”: Anxious And Avoidant Attachments In Opie’S Adeline Mowbray, Meghan E. Hodges Jan 2023

“By That Daughter’S Most Devoted Affection”: Anxious And Avoidant Attachments In Opie’S Adeline Mowbray, Meghan E. Hodges

Comparative Woman

Attachment theory, or the theory that one’s personality and social development is informed greatly by the infant-parent bond, largely arises in the 1950s with the work of John Bowlby. Although the phenomenon was only then beginning to be scientifically evaluated, it has long been observed that the relationship one has with one’s parents is a determinant factor in one’s development. This work investigates the impact of the failure to heal the insecure attachment Amelie Opie’s Adeline Mowbray (1808). Adeline, having grown up in her distant mother’s intellectual shadow, develops a neurotic attachment to her mother which causes romantic maladjustment in …


Modern-Day Neanderthal Genetic Lifewriting, Interspecies Romance, And The Promise Of Multispecies Autoethnography, Travis Brisini Jan 2023

Modern-Day Neanderthal Genetic Lifewriting, Interspecies Romance, And The Promise Of Multispecies Autoethnography, Travis Brisini

Faculty Publications

Advances in contemporary genetic science have reshaped the narratives whereby individuals and communities make sense of their personal, family, and communal histories. In this process, unknown connections have been revealed and familiar orthodoxies disrupted. This essay examines the consequences of a particularly unusual revelation - the dawning awareness of the presence of nonhuman and archaic human DNA in human genetic lines - for efforts at writing about identity and society. In this autoethnographic account, I examine my own genetic inheritance of Neanderthal DNA, and posit a performative concept of genetic life writing that begins to unpack the complexities of this …


Preliminary Findings From A Collaborative Storytelling Program On Life Participation And Communication Among Persons With Aphasia, Bijoyaa Mohapatra, Ranjini Mohan Jan 2023

Preliminary Findings From A Collaborative Storytelling Program On Life Participation And Communication Among Persons With Aphasia, Bijoyaa Mohapatra, Ranjini Mohan

Faculty Publications

Aims: The purpose of this study is to evaluate the outcomes of a remotely delivered collaborative storytelling program based on the TimeslipsTM approach in persons with aphasia (PWA). The program aims to improve social interaction, communication, and participation through a guided experience. Methods: Six PWA of mild-moderate severity and of fluent and nonfluent types participated in the program twice a week for seven weeks. They collaboratively created 28 free-form stories from staged pictures. PWA were tested pre- and post-treatment on several validated outcome measures representing each of the Living with Aphasia: Framework for Outcome Measurement (A-FROM) domains. PWA self-rated on …


Acute Stressors Do Not Impair Short-Term Memory Or Attention In An Aged Mouse Model Of Amyloidosis, Giuliana M. Dimarco, Breanna N. Harris, Alena V. Savonenko, Paul L. Soto Jan 2023

Acute Stressors Do Not Impair Short-Term Memory Or Attention In An Aged Mouse Model Of Amyloidosis, Giuliana M. Dimarco, Breanna N. Harris, Alena V. Savonenko, Paul L. Soto

Faculty Publications

Memory impairment in Alzheimer’s disease patients is thought to be associated with the accumulation of amyloid-beta peptides and tau proteins. However, inconsistent reports of cognitive deficits in pre-clinical studies have raised questions about the link between amyloid-beta and cognitive decline. One possible explanation may be that studies reporting memory deficits often involve behavioral assessments that entail a high stress component. In contrast, in tasks without a high stress component transgenic mice do not consistently show declines in memory. The glucocorticoid cascade hypothesis of aging and the vicious cycle of stress framework suggest that stress exacerbates dementia progression by initiating a …


Process Scores On Measures Of Learning And Memory: Issue 1, Dustin B. Hammers, Matthew Calamia Jan 2023

Process Scores On Measures Of Learning And Memory: Issue 1, Dustin B. Hammers, Matthew Calamia

Faculty Publications

No abstract provided.


Process Scores On Measures Of Learning And Memory: Issue 2, Matthew Calamia, Dustin B. Hammers Jan 2023

Process Scores On Measures Of Learning And Memory: Issue 2, Matthew Calamia, Dustin B. Hammers

Faculty Publications

No abstract provided.


Remote Assessment Of Negative Symptoms Of Schizophrenia, David G. Daniel, Alex S. Cohen, Dawn Velligan, Phillip D. Harvey, Larry Alphs, Michael Davidson, William Potter, Alan Kott, Nina Schooler, Christopher R. Brodie, Raeanne C. Moore, Pierre Lindenmeyer, Stephen R. Marder Jan 2023

Remote Assessment Of Negative Symptoms Of Schizophrenia, David G. Daniel, Alex S. Cohen, Dawn Velligan, Phillip D. Harvey, Larry Alphs, Michael Davidson, William Potter, Alan Kott, Nina Schooler, Christopher R. Brodie, Raeanne C. Moore, Pierre Lindenmeyer, Stephen R. Marder

Faculty Publications

In contrast to the validated scales for face-to-face assessment of negative symptoms, no widely accepted tools currently exist for remote monitoring of negative symptoms. Remote assessment of negative symptoms can be broadly divided into 3 categories: (1) remote administration of an existing negative-symptom scale by a clinician, in real time, using videoconference technology to communicate with the patient; (2) direct inference of negative symptoms through detection and analysis of the patient's voice, appearance, or activity by way of the patient's smartphone or other device; and (3) ecological momentary assessment, in which the patient self-reports their condition upon receipt of periodic …


Guest Editor’S Introduction: The Need For A Broader, More Inclusive Approach To Child And Adolescent Suicide Prevention, Ryan M. Hill Jan 2023

Guest Editor’S Introduction: The Need For A Broader, More Inclusive Approach To Child And Adolescent Suicide Prevention, Ryan M. Hill

Faculty Publications

No abstract provided.


The Effects Of Internet-Based Cognitive Behavioral Therapy For Suicidal Ideation Or Behaviors On Depression, Anxiety, And Hopelessness In Individuals With Suicidal Ideation: Systematic Review And Meta-Analysis Of Individual Participant Data, Lasse B. Sander, Marie Beisemann, Philipp Doebler, Hannah Moon Micklitz, Ad Kerkhof, Pim Cuijpers, Philip Batterham, Alison Calear, Helen Christensen, Eva De Jaegere, Matthias Domhardt, Annette Erlangsen, Ozlem Eylem-Van Bergeijk, Ryan Hill, Charlotte Mühlmann, Marie Österle, Jeremy Pettit, Gwendolyn Portzky, Lena Steubl, Bregje Van Spijker, Joseph Tighe, Aliza Werner-Seidler, Rebekka Büscher Jan 2023

The Effects Of Internet-Based Cognitive Behavioral Therapy For Suicidal Ideation Or Behaviors On Depression, Anxiety, And Hopelessness In Individuals With Suicidal Ideation: Systematic Review And Meta-Analysis Of Individual Participant Data, Lasse B. Sander, Marie Beisemann, Philipp Doebler, Hannah Moon Micklitz, Ad Kerkhof, Pim Cuijpers, Philip Batterham, Alison Calear, Helen Christensen, Eva De Jaegere, Matthias Domhardt, Annette Erlangsen, Ozlem Eylem-Van Bergeijk, Ryan Hill, Charlotte Mühlmann, Marie Österle, Jeremy Pettit, Gwendolyn Portzky, Lena Steubl, Bregje Van Spijker, Joseph Tighe, Aliza Werner-Seidler, Rebekka Büscher

Faculty Publications

Background: Suicide is a global public health problem. Digital interventions are considered a low-threshold treatment option for people with suicidal ideation or behaviors. Internet-based cognitive behavioral therapy (iCBT) targeting suicidal ideation has demonstrated effectiveness in reducing suicidal ideation. However, suicidal ideation often is related to additional mental health problems, which should be addressed for optimal care. Yet, the effects of iCBT on related symptoms, such as depression, anxiety, and hopelessness, remain unclear. Objective: We aimed to analyze whether digital interventions targeting suicidal ideation had an effect on related mental health symptoms (depression, anxiety, and hopelessness). Methods: We systematically searched CENTRAL, …


Effects Of Episodic Food Insecurity On Psychological And Physiological Responses In African American Women With Obesity (Responses): Protocol For A Longitudinal Observational Cohort Study, Candice A. Myers, Robbie A. Beyl, Daniel S. Hsia, Melissa N. Harris, Isabella J. Reed, Danielle D. Eliser, Lauren Bagneris, John W. Apolzan Jan 2023

Effects Of Episodic Food Insecurity On Psychological And Physiological Responses In African American Women With Obesity (Responses): Protocol For A Longitudinal Observational Cohort Study, Candice A. Myers, Robbie A. Beyl, Daniel S. Hsia, Melissa N. Harris, Isabella J. Reed, Danielle D. Eliser, Lauren Bagneris, John W. Apolzan

Clinical Research Faculty Publications

Background: Food insecurity is a risk factor for multiple chronic diseases, including obesity. Importantly, both food insecurity and obesity are more prevalent in African American women than in other groups. Furthermore, food insecurity is considered a cyclic phenomenon, with episodes of food adequacy (ie, enough food to eat) and food shortage (ie, not enough food to eat). More research is needed to better understand why food insecurity is linked to obesity, including acknowledging the episodic nature of food insecurity as a stressor and identifying underlying mechanisms. Objective: The objective of this study is to investigate the episodic nature of food …


Editorial: Stress-Induced Weight Changes, Hassan M. Heshmati, Livio Luzi, Frank L. Greenway, Candida J. Rebello Jan 2023

Editorial: Stress-Induced Weight Changes, Hassan M. Heshmati, Livio Luzi, Frank L. Greenway, Candida J. Rebello

Clinical Research Faculty Publications

No abstract provided.


Core Issues, Case Studies, And The Need For Expanded Legacy African American Genomics, Fatimah Jackson, Carter Clinton, Jennifer Caldwell Jan 2023

Core Issues, Case Studies, And The Need For Expanded Legacy African American Genomics, Fatimah Jackson, Carter Clinton, Jennifer Caldwell

Population and Public Health Science Faculty Publications

Introduction: Genomic studies of Legacy African Americans have a tangled and convoluted history in western science. In this review paper, core issues affecting African American genomic studies are addressed and two case studies, the New York African Burial Ground and the Gullah Geechee peoples, are presented to highlight the current status of genomic research among Africa Americans. Methods: To investigate our target population’s core issues, a metadatabase derived from 22 publicly accessible databases were reviewed, evaluated, and synthesized to identify the core bioethical issues prevalent during the centuries of the African American presence in North America. The sequence of metadatabase …


Comparison Of Selected Exercise Training Modalities In The Management Of Pcos: A Systematic Review And Meta-Analysis To Inform Evidence-Based Guidelines, Giorgia E. Colombo, Xela Dafauce Bouzo, Rhiannon K. Patten, Aya Mousa, Chau Thien Tay, Loyal Pattuwage, Helena J. Teede, Leanne M. Redman, Angelica Lindén Hirschberg, Angelo Sabag Jan 2023

Comparison Of Selected Exercise Training Modalities In The Management Of Pcos: A Systematic Review And Meta-Analysis To Inform Evidence-Based Guidelines, Giorgia E. Colombo, Xela Dafauce Bouzo, Rhiannon K. Patten, Aya Mousa, Chau Thien Tay, Loyal Pattuwage, Helena J. Teede, Leanne M. Redman, Angelica Lindén Hirschberg, Angelo Sabag

Clinical Research Faculty Publications

Background: Polycystic ovary syndrome (PCOS) is a common endocrine condition in women of reproductive age that often presents with reproductive, metabolic, and psychological symptoms. While exercise is part of the management of PCOS, it is unclear which form of exercise may be most effective and for which outcomes. Aim: In order to inform the updated 2023 International evidence-based guideline for the assessment and management of polycystic ovary syndrome, this systematic review aimed to determine the exercise modality that provides the greatest improvement in anthropometric, metabolic, hormonal/reproductive, and psychological outcomes in adult women with PCOS. Methods: Five databases were searched from …


Race And Sex Differences In The Association Between Lifespan Glycemic Status And Midlife Cognitive Function: The Bogalusa Heart Study, Kathryn L. Gwizdala, Lydia A. Bazzano, Robert L. Newton, Owen T. Carmichael Jan 2023

Race And Sex Differences In The Association Between Lifespan Glycemic Status And Midlife Cognitive Function: The Bogalusa Heart Study, Kathryn L. Gwizdala, Lydia A. Bazzano, Robert L. Newton, Owen T. Carmichael

Clinical Research Faculty Publications

Introduction: Glycemic markers throughout life are associated with increased risk of midlife cognitive decline, yet it is unclear whether these associations differ by race and sex. Methods: This study used cross-sectional analysis of prospectively maintained cohort. 1,295 participants in the Bogalusa Heart Study, a biracial epidemiological cohort located in a micropolitan area core setting, provided fasting plasma insulin (FPI) and glucose (FPG) biannually from 1973 to 2016. Memory, executive function (EF), attention, working memory (WM), and global cognition (GC), collected 2013–2016. Glycemic markers (i.e., FPG, FPI, and HOMA-IR) averaged within lifespan epochs (≤ 20 years, childhood/adolescence (C/A); 21–40 years, early …


Midlife Neuropsychological Profiles And Associated Vascular Risk: The Bogalusa Heart Study, Ileana De Anda-Duran, Vijaya B. Kolachalama, Owen T. Carmichael, Phillip H. Hwang, Camilo Fernandez, Rhoda Au, Lydia A. Bazzano, David J. Libon Jan 2023

Midlife Neuropsychological Profiles And Associated Vascular Risk: The Bogalusa Heart Study, Ileana De Anda-Duran, Vijaya B. Kolachalama, Owen T. Carmichael, Phillip H. Hwang, Camilo Fernandez, Rhoda Au, Lydia A. Bazzano, David J. Libon

Clinical Research Faculty Publications

Background: Individuals with Alzheimer's disease (AD) often present with coexisting vascular pathology that is expressed to different degrees and can lead to clinical heterogeneity. Objective: To examine the utility of unsupervised statistical clustering approaches in identifying neuropsychological (NP) test performance subtypes that closely correlate with carotid intima-media thickness (cIMT) in midlife. Methods: A hierarchical agglomerative and k-means clustering analysis based on NP scores (standardized for age, sex, and race) was conducted among 1,203 participants (age 48±5.3 years) from the Bogalusa Heart Study. Regression models assessed the association between cIMT ≥50th percentile and NP profiles, and global cognitive score (GCS) tertiles …


A Data-Driven Examination Of Apathy And Depressive Symptoms In Dementia With Independent Replication, Miguel Vasconcelos Da Silva, Gerardo Javier Melendez-Torres, Zahinoor Ismail, Ingelin Testad, Clive Ballard, Byron Creese, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles Decarli, Bret Borowski Jan 2023

A Data-Driven Examination Of Apathy And Depressive Symptoms In Dementia With Independent Replication, Miguel Vasconcelos Da Silva, Gerardo Javier Melendez-Torres, Zahinoor Ismail, Ingelin Testad, Clive Ballard, Byron Creese, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles Decarli, Bret Borowski

Clinical Research Faculty Publications

Apathy is one of the most common neuropsychiatric symptoms (NPS) and is associated with poor clinical outcomes. Research that helps define the apathy phenotype is urgently needed, particularly for clinical and biomarker studies. We used latent class analysis (LCA) with two independent cohorts to understand how apathy and depression symptoms co-occur statistically. We further explored the relationship between latent class membership, demographics, and the presence of other NPS. The LCA identified a four-class solution (no symptoms, apathy, depression, and combined apathy/depression), reproducible over both cohorts, providing robust support for an apathy syndrome distinct from depression and confirming that an apathy/depression …