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Lignin Cationization For The Removal Of Phosphates And Nitrates From Effluents Of Wastewater Treatment Plants, Fannyuy V. Kewir Dec 2024

Lignin Cationization For The Removal Of Phosphates And Nitrates From Effluents Of Wastewater Treatment Plants, Fannyuy V. Kewir

LSU Master's Theses

The removal of phosphates and nitrates from wastewater treatment plant (WWTP) effluents is important for preventing pollution of receiving waters. In this study, we chemically modified alkaline lignin (aLN) with quaternary ammonium groups to obtain biodegradable cationic lignin (cLN). We characterized the cLN and tested its efficacy for removing phosphates and nitrates in a lab setting and on field-collected WWTP samples. Adsorption isotherm and kinetic studies were performed in aqueous media, and the effects of several variables (contact time, pH, initial concentration, and adsorbent dose) were investigated. The Langmuir isotherm described phosphate and nitrate adsorption well, with R2 values of …

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Biological Control Of Roseau Cane Scale With Parasitoid Wasps In Louisiana, Tanner C. Sparks Dec 2024

Biological Control Of Roseau Cane Scale With Parasitoid Wasps In Louisiana, Tanner C. Sparks

LSU Doctoral Dissertations

Roseau cane scale, Nipponaclerda biwakoensis (Hemiptera: Aclerdidae) is an invasive species of scale insect negatively impacting Phragmites australis (Cyperales: Poaceae) stands within the Mississippi River Delta. The scales were first detected in 2017 from reports of Phragmites die-back within the MRD by landowners. Initial range surveys located RCS infested Phragmites stands were primarily limited to southeastern Louisiana with a single population near Port Arthur, Texas. Follow-up field surveys conducted annually from 2021 to 2023 monitoring further range expansion by the scale show the current range extends nearly 600 km between High Island, Texas and Bayou la Batre, Alabama. Climate matching …

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Screen Media, Obesity, And Nutrition, Amanda E. Staiano, Alyssa M. Button, Gary S. Goldfield, Thomas N. Robinson, Jorge Mota, Susan J. Woolford, Peter T. Katzmarzyk Dec 2024

Screen Media, Obesity, And Nutrition, Amanda E. Staiano, Alyssa M. Button, Gary S. Goldfield, Thomas N. Robinson, Jorge Mota, Susan J. Woolford, Peter T. Katzmarzyk

Population and Public Health Science Faculty Publications

This chapter provides an update on and the synthesis of the most current evidence on screen use, nutritional intake, and obesity in youth. The strongest evidence of a mechanism linking screen media use to obesity is through repeated exposures to unhealthy food marketing and excess eating while viewing screens. Evidence of the neurocognitive effects on dietary consumption via the effects of executive function, satiety, and memory is emerging. Interventions to reduce children's screen time or to incorporate screen media into improving nutrition and obesity outcomes have had mixed results. The evidence base is also limited by imprecise measurements of screen …

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Digital Screen Media Use, Movement Behaviors, And Child Health, Mark S. Tremblay, Nicholas Kuzik, Stuart J.H. Biddle, Valerie Carson, Mai J.M. Chinapaw, Dorothea Dumuid, Wendy Yajun Huang, Travis J. Saunders, Amanda E. Staiano, Russell R. Pate Dec 2024

Digital Screen Media Use, Movement Behaviors, And Child Health, Mark S. Tremblay, Nicholas Kuzik, Stuart J.H. Biddle, Valerie Carson, Mai J.M. Chinapaw, Dorothea Dumuid, Wendy Yajun Huang, Travis J. Saunders, Amanda E. Staiano, Russell R. Pate

Population and Public Health Science Faculty Publications

This chapter summarizes the associations between children's digital screen media use (DSMU) and their health, within the 24-h movement behavior framework (physical activities, sedentary behaviors, sleep), provides recommendations for healthy DSMU, and highlights future research directions. Key concepts include behavior displacement, combined associations, and DSMU context and content. Displacement examples include more DSMU decreasing time for healthier behaviors (e.g., physical activity or sleep) or replacing reading books and magazines with DSMU alternatives (e.g., texting, social media). How DSMU affects the relationships between various combinations of movement behaviors and children's health is largely unknown. Total DSMU is most frequently studied, but …

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Nanofabrication Of Tetraphenyl Porphyrin Surface Assemblies Linked With Tin Tetrachloride: A Scanning Probe Microscopy Investigation, Quynh Do Dec 2024

Nanofabrication Of Tetraphenyl Porphyrin Surface Assemblies Linked With Tin Tetrachloride: A Scanning Probe Microscopy Investigation, Quynh Do

LSU Doctoral Dissertations

Scanning probe microscopy (SPM) and colloidal lithography methods were used to study the covalent coupling of porphyrins to surfaces. In this dissertation, experimental methods for SPM operation, techniques, and applications are described. Measurement of tip-sample interactions between a sharp tip and surface is translated into digital image data maps with x-, y-, and z-data. Colloidal lithography can be used to fabricate test platforms for AFM studies. The periodicity and arrangement of the designed nanostructures is determined by the size of the colloidal particles used for surface masks. Data processing is required to obtain images and topography information from raw AFM …

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Net Evaporation-Induced Mangrove Area Loss Across Low-Lying Caribbean Islands, Isamar M. Cortés, Jorge Lorenzo-Trueba, Andre S. Rovai, Robert R. Twilley, Mark Chopping, Temilola Fatoyinbo Dec 2024

Net Evaporation-Induced Mangrove Area Loss Across Low-Lying Caribbean Islands, Isamar M. Cortés, Jorge Lorenzo-Trueba, Andre S. Rovai, Robert R. Twilley, Mark Chopping, Temilola Fatoyinbo

Faculty Publications

Although mangroves provide many beneficial ecosystem services, such as blue carbon storage and coastal protection, they are currently under threat due to changes in climate conditions, such as prolonged drought exposure. Under drought conditions, evaporation exceeds precipitation and high soil salinities can lead to stunted growth and die-back. To quantify this interplay, we developed a database for low-lying and uninhabited mangrove islands in the Caribbean under various evaporation and precipitation regimes. We extracted physical and biological information from each island using remote sensing techniques and coupled it with a process-based model. We used this database to develop a model that …

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A Temperature Tipping Point In Hypoxic Zone Size, R. Eugene Turner, Nancy N. Rabalais, Cassandra N. Glaspie Dec 2024

A Temperature Tipping Point In Hypoxic Zone Size, R. Eugene Turner, Nancy N. Rabalais, Cassandra N. Glaspie

Faculty Publications

Temperature increases will have ubiquitous effects on aquatic food webs, from microbes to consumers, and affect the quality and quantity of carbon flows within and between water layers. A decline in the biological pump moving carbon from surface to lower layers is anticipated. We reviewed 37 years of data on hypoxic zone size and water quality in the northern Gulf of Mexico to determine if air and bottom water temperature increases (0.5°C decade−1) are significantly related to variations in its areal size. There was no significant decline in important river water quality in the 24 years since the …

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Detecting, Attributing, And Projecting Global Marine Ecosystem And Fisheries Change: Fishmip 2.0, Julia L. Blanchard, Camilla Novaglio, Olivier Maury, Cheryl S. Harrison, Colleen M. Petrik, Denisse Fierro-Arcos, Kelly Ortega-Cisneros, Andrea Bryndum-Buchholz, Tyler D. Eddy, Ryan Heneghan, Kelsey Roberts, Jacob Schewe, Daniele Bianchi, Jerome Guiet, P. Daniel Van Denderen, Juliano Palacios-Abrantes, Xiao Liu, Charles A. Stock, Yannick Rousseau, Matthias Büchner, Ezekiel O. Adekoya, Cathy Bulman, William Cheung, Villy Christensen, Marta Coll, Leonardo Capitani, Samik Datta, Elizabeth A. Fulton, Alba Fuster, Victoria Garza, Matthieu Lengaigne, Max Lindmark, Kieran Murphy Dec 2024

Detecting, Attributing, And Projecting Global Marine Ecosystem And Fisheries Change: Fishmip 2.0, Julia L. Blanchard, Camilla Novaglio, Olivier Maury, Cheryl S. Harrison, Colleen M. Petrik, Denisse Fierro-Arcos, Kelly Ortega-Cisneros, Andrea Bryndum-Buchholz, Tyler D. Eddy, Ryan Heneghan, Kelsey Roberts, Jacob Schewe, Daniele Bianchi, Jerome Guiet, P. Daniel Van Denderen, Juliano Palacios-Abrantes, Xiao Liu, Charles A. Stock, Yannick Rousseau, Matthias Büchner, Ezekiel O. Adekoya, Cathy Bulman, William Cheung, Villy Christensen, Marta Coll, Leonardo Capitani, Samik Datta, Elizabeth A. Fulton, Alba Fuster, Victoria Garza, Matthieu Lengaigne, Max Lindmark, Kieran Murphy

Faculty Publications

There is an urgent need for models that can robustly detect past and project future ecosystem changes and risks to the services that they provide to people. The Fisheries and Marine Ecosystem Model Intercomparison Project (FishMIP) was established to develop model ensembles for projecting long-term impacts of climate change on fisheries and marine ecosystems while informing policy at spatio-temporal scales relevant to the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) framework. While contributing FishMIP models have improved over time, large uncertainties in projections remain, particularly in coastal and shelf seas where most of the world's fisheries occur. Furthermore, previous FishMIP climate …

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Qacdes: Qos-Aware Context-Sensitive Design Of Cyber-Physical Systems, Subhajit Sidhanta, Chanachok Chokwitthaya, Yimin Zhu, Supratik Mukhopadhyay Dec 2024

Qacdes: Qos-Aware Context-Sensitive Design Of Cyber-Physical Systems, Subhajit Sidhanta, Chanachok Chokwitthaya, Yimin Zhu, Supratik Mukhopadhyay

Faculty Publications

There is a lot of confusion and ambiguity regarding the quantification of the Quality of Service (QoS) of a system, especially for cyber-physical systems (CPS) involved in automating or controlling the operations in built environments and critical urban infrastructures, such as office buildings, factories, transportation systems, smart cities, etc. In these cases, the QoS, as experienced by human users, depends on the context in which they (i.e., humans) interact with these systems. Traditionally, the QoS of a CPS has been defined in terms of absolute metrics. Such measures are unable to take into account the variations in performance due to …

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Glucagon-Like Peptide-1 Receptor Agonist-Based Agents And Weight Loss Composition: Filling The Gaps, Robert L. Dubin, Steven B. Heymsfield, Eric Ravussin, Frank L. Greenway Dec 2024

Glucagon-Like Peptide-1 Receptor Agonist-Based Agents And Weight Loss Composition: Filling The Gaps, Robert L. Dubin, Steven B. Heymsfield, Eric Ravussin, Frank L. Greenway

Clinical Research Faculty Publications

Excess adiposity is at the root of type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as first-line treatments for T2D based on significant weight loss results. The composition of weight loss using most diets consists of < 25% fat-free mass (FFM) loss, with the remainder from fat stores. Higher amounts of weight loss (achieved with metabolic bariatric surgery) result in greater reductions in FFM. Our aim was to assess the impact that GLP-1RA-based treatments have on FFM. We analysed studies that reported changes in FFM with the following agents: exenatide, liraglutide, semaglutide, and the dual incretin receptor agonist tirzepatide. We performed an analysis of various weight loss interventions to provide a reference for expected changes in FFM. We evaluated studies using dual-energy X-ray absorptiometry (DXA) for measuring FFM (a crude surrogate for skeletal muscle). In evaluating the composition of weight loss, the percentage lost as fat-free mass (%FFML) was equal to ΔFFM/total weight change. The %FFML using GLP-1RA-based agents was between 20% and 40%. In the 28 clinical trials evaluated, the proportion of FFM loss was highly variable, but the majority reported %FFML exceeding 25%. Our review was limited to small substudies and the use of DXA, which does not measure skeletal muscle mass directly. Since FFM contains a variable amount of muscle (approximately 55%), this indirect measure may explain the heterogeneity in the data. Assessing quantity and quality of skeletal muscle using advanced imaging (magnetic resonance imaging) with functional testing will help fill the gaps in our current understanding.

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The Role Of Government Assistance, Housing, And Employment On Postpartum Maternal Health Across Income And Race: A Mixed Methods Study, Chelsea L. Kracht, Kelsey O. Goynes, Madison Dickey, Briasha Jones, Emerson Simeon, Jada Butler, Maryam Kebbe, Kaja Falkenhain, Emily W. Harville, Elizabeth F. Sutton, Leanne M. Redman Dec 2024

The Role Of Government Assistance, Housing, And Employment On Postpartum Maternal Health Across Income And Race: A Mixed Methods Study, Chelsea L. Kracht, Kelsey O. Goynes, Madison Dickey, Briasha Jones, Emerson Simeon, Jada Butler, Maryam Kebbe, Kaja Falkenhain, Emily W. Harville, Elizabeth F. Sutton, Leanne M. Redman

Clinical Research Faculty Publications

Background: Stressful large-scale events, such as the COVID-19 pandemic and natural disasters, impact birthing individuals’ postpartum experiences and their mental health. Resultant changes in government assistance, housing, and employment may further exacerbate these impacts, with differences experienced by varying income levels and races. This study aimed to examine maternal depression and anxiety in postpartum individuals by income and race during a stressful large-scale event, and the mediating role of government assistance, housing, and employment. Methods: An explanatory sequential mixed methods study was conducted (QUANT + QUAL). For aim 1 (quantitative), birthing individuals who delivered during peak pandemic (June 2020 - …

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A Systematic Umbrella Review And Meta-Meta-Analysis Of Ehealth And Mhealth Interventions For Improving Lifestyle Behaviours, Ben Singh, Mavra Ahmed, Amanda E. Staiano, Claire Gough, Jasmine Petersen, Corneel Vandelanotte, Chelsea Kracht, Christopher Huong, Zenong Yin, Maria F. Vasiloglou, Chen Chia Pan, Camille E. Short, Matthew Mclaughlin, Lauren Von Klinggraeff, Christopher D. Pfledderer, Lisa J. Moran, Alyssa M. Button, Carol A. Maher Dec 2024

A Systematic Umbrella Review And Meta-Meta-Analysis Of Ehealth And Mhealth Interventions For Improving Lifestyle Behaviours, Ben Singh, Mavra Ahmed, Amanda E. Staiano, Claire Gough, Jasmine Petersen, Corneel Vandelanotte, Chelsea Kracht, Christopher Huong, Zenong Yin, Maria F. Vasiloglou, Chen Chia Pan, Camille E. Short, Matthew Mclaughlin, Lauren Von Klinggraeff, Christopher D. Pfledderer, Lisa J. Moran, Alyssa M. Button, Carol A. Maher

Population and Public Health Science Faculty Publications

The aim of this meta-meta-analysis was to systematically review randomised controlled trial (RCT) evidence examining the effectiveness of e- and m-Health interventions designed to improve physical activity, sedentary behaviour, healthy eating and sleep. Nine electronic databases were searched for eligible studies published from inception to 1 June 2023. Systematic reviews with meta-analyses of RCTs that evaluate e- and m-Health interventions designed to improve physical activity, sedentary behaviour, sleep and healthy eating in any adult population were included. Forty-seven meta-analyses were included, comprising of 507 RCTs and 206,873 participants. Interventions involved mobile apps, web-based and SMS interventions, with 14 focused on …

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Multiomics Analysis To Explore Blood Metabolite Biomarkers In An Alzheimer’S Disease Neuroimaging Initiative Cohort, Takaki Oka, Yuki Matsuzawa, Momoka Tsuneyoshi, Yoshitaka Nakamura, Ken Aoshima, Hiroshi Tsugawa, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles Decarli, Bret Borowski Dec 2024

Multiomics Analysis To Explore Blood Metabolite Biomarkers In An Alzheimer’S Disease Neuroimaging Initiative Cohort, Takaki Oka, Yuki Matsuzawa, Momoka Tsuneyoshi, Yoshitaka Nakamura, Ken Aoshima, Hiroshi Tsugawa, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles Decarli, Bret Borowski

Clinical Research Faculty Publications

Alzheimer's disease (AD) is a neurodegenerative disease that commonly causes dementia. Identifying biomarkers for the early detection of AD is an emerging need, as brain dysfunction begins two decades before the onset of clinical symptoms. To this end, we reanalyzed untargeted metabolomic mass spectrometry data from 905 patients enrolled in the AD Neuroimaging Initiative (ADNI) cohort using MS-DIAL, with 1,304,633 spectra of 39,108 unique biomolecules. Metabolic profiles of 93 hydrophilic metabolites were determined. Additionally, we integrated targeted lipidomic data (4873 samples from 1524 patients) to explore candidate biomarkers for predicting progressive mild cognitive impairment (pMCI) in patients diagnosed with AD …

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Investigating The Role That Calcium And The Membrane Play In 8r-Lipoxygenase Catalysis, Kaelie Bernard Dec 2024

Investigating The Role That Calcium And The Membrane Play In 8r-Lipoxygenase Catalysis, Kaelie Bernard

Honors Capstones

No abstract provided.

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Tailoring Ipm Plans To Fight A Cloaked Pest: Helping Smallholder Farmers Combat The Sweetpotato Weevil In Sub-Saharan Africa, Chad A. Keyser, Frederick S. Walters, Haley Turner, Elka Armstrong, Jeff Davis, Brooke Bissinger, Brant Johnson, Agnes Alajo, Paul Musana, Joseph Odongo, Benard Yada, Milton A. Otema Dec 2024

Tailoring Ipm Plans To Fight A Cloaked Pest: Helping Smallholder Farmers Combat The Sweetpotato Weevil In Sub-Saharan Africa, Chad A. Keyser, Frederick S. Walters, Haley Turner, Elka Armstrong, Jeff Davis, Brooke Bissinger, Brant Johnson, Agnes Alajo, Paul Musana, Joseph Odongo, Benard Yada, Milton A. Otema

Faculty Publications

Africa accounts for a significant portion of the world’s sweetpotato production where it is widely grown as a staple crop. In sub-Saharan Africa (SSA), sweetpotato serves as an important year-round source of calories and nutrition, a form of income for smallholder and pre-commercial farmers, and is increasingly used as silage for animal feed. However, yield per hectare is considerably lower in SSA than from other regions primarily due to sweetpotato weevils (SPW, Cylas spp., Coleoptera: Brentidae). Weevil feeding causes physical damage to the root and can induce chemical responses that give the storage root a bitter taste, both of which …

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Resilient, Environment Tolerant And Biocompatible Electroluminescent Devices With Enhanced Luminance Based On Compliant And Self-Adhesive Electrodes, Ya Lu, Yuanyuan Chen, Haoyu Sun, Fang Deng, Changtong Mei, Xinwu Xu, Qinglin Wu, Huining Xiao, Yiying Yue, Jingquan Han Dec 2024

Resilient, Environment Tolerant And Biocompatible Electroluminescent Devices With Enhanced Luminance Based On Compliant And Self-Adhesive Electrodes, Ya Lu, Yuanyuan Chen, Haoyu Sun, Fang Deng, Changtong Mei, Xinwu Xu, Qinglin Wu, Huining Xiao, Yiying Yue, Jingquan Han

Faculty Publications

Electroluminescent (EL) devices are of great significance for expanding the application range of optoelectronics. However, the realization of EL devices with environment-tolerance, stretchability, mechanical cycling stability, self-adhesion, biocompatibility, and high dielectric constant still remains a challenge. Herein, a type of EL device with enhanced comprehensive performances composing of a chlorinated barium titanate/phosphor/polydimethylsiloxane (Cl-BT/phosphor/PDMS) luminescent layer sandwiched between two silver nanowire-cellulose nanocrystal with II crystalline allomorph/Triton X-100 modified polydimethylsiloxane (AgNW-CNC II/TX-PDMS) electrodes fabricated through a full solution-processing strategy is proposed. Environmentally-friendly CNC II with high transmittance acts as an antioxidant, dispersant and film-former for AgNWs. The hydrophilic modification of TX to …

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Early Life Energy Balance: The Development Of Infant Energy Expenditure And Intake In The Context Of Obesity, Emily W. Flanagan, Leanne M. Redman Dec 2024

Early Life Energy Balance: The Development Of Infant Energy Expenditure And Intake In The Context Of Obesity, Emily W. Flanagan, Leanne M. Redman

Clinical Research Faculty Publications

Purpose of Review: This review aims to provide a summary of the current knowledge on measurement tools and most recent evidence for prenatal and postnatal modulators of energy balance in young infants. Recent Findings: The prevention of pediatric obesity depends upon curating the perfect imbalance of energy intake to energy expenditure, taking into consideration the energy needs for healthy growth. We summarize the recent evidence for the programming of fetal and infant metabolism influenced by maternal preconception health, prenatal metabolic milieu, and physical activity behaviors. In the early postnatal environment, caregiver feeding behaviors shape the extent of energy imbalance through …

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Effective Interventions In Preventing Gestational Diabetes Mellitus: A Systematic Review And Meta-Analysis, Wubet Worku Takele, Kimberly K. Vesco, Jami Josefson, Leanne M. Redman, Wesley Hannah, Wesley Hannah, Maxine P. Bonham, Mingling Chen, Sian C. Chivers, Andrea J. Fawcett, Andrea J. Fawcett, Jessica A. Grieger, Nahal Habibi, Gloria K.W. Leung, Kai Liu, Eskedar G. Mekonnen, Eskedar G. Mekonnen, Maleesa Pathirana, Alejandra Quinteros, Rachael Taylor, Gebresilasea G. Ukke, Gebresilasea G. Ukke, Shao J. Zhou, Paul W. Franks, Stephen S. Rich, Robert Wagner, Tina Vilsbøll, Miriam S. Udler, Tiinamaija Tuomi, Arianne Sweeting, Emily K. Sims, Jennifer L. Sherr, Robert K. Semple, Rebecca M. Reynolds Dec 2024

Effective Interventions In Preventing Gestational Diabetes Mellitus: A Systematic Review And Meta-Analysis, Wubet Worku Takele, Kimberly K. Vesco, Jami Josefson, Leanne M. Redman, Wesley Hannah, Wesley Hannah, Maxine P. Bonham, Mingling Chen, Sian C. Chivers, Andrea J. Fawcett, Andrea J. Fawcett, Jessica A. Grieger, Nahal Habibi, Gloria K.W. Leung, Kai Liu, Eskedar G. Mekonnen, Eskedar G. Mekonnen, Maleesa Pathirana, Alejandra Quinteros, Rachael Taylor, Gebresilasea G. Ukke, Gebresilasea G. Ukke, Shao J. Zhou, Paul W. Franks, Stephen S. Rich, Robert Wagner, Tina Vilsbøll, Miriam S. Udler, Tiinamaija Tuomi, Arianne Sweeting, Emily K. Sims, Jennifer L. Sherr, Robert K. Semple, Rebecca M. Reynolds

Clinical Research Faculty Publications

Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR) framework was used to examine intervention characteristics (who, what, when, where, and how). Subgroup analysis was performed by intervention characteristics. Results: 116 studies involving 40,940 participants are included. Group-based physical activity interventions (RR 0.66; 95% CI 0.46, 0.95) reduce the incidence of GDM compared with individual or mixed (individual and group) …

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Precision Stratification Of Prognostic Risk Factors Associated With Outcomes In Gestational Diabetes Mellitus: A Systematic Review, Zhila Semnani-Azad, Romy Gaillard, Alice E. Hughes, Kristen E. Boyle, Kristen E. Boyle, Deirdre K. Tobias, Paul W. Franks, Stephen S. Rich, Robert Wagner, Tina Vilsbøll, Kimberly K. Vesco, Miriam S. Udler, Tiinamaija Tuomi, Arianne Sweeting, Emily K. Sims, Jennifer L. Sherr, Robert K. Semple, Rebecca M. Reynolds, Maria J. Redondo, Leanne M. Redman, Richard E. Pratley, Rodica Pop-Busui, Toni I. Pollin, Wei Perng, Ewan R. Pearson, Susan E. Ozanne, Katharine R. Owen, Richard Oram, Rinki Murphy, Viswanathan Mohan, Shivani Misra, James B. Meigs, Nestoras Mathioudakis, Chantal Mathieu Dec 2024

Precision Stratification Of Prognostic Risk Factors Associated With Outcomes In Gestational Diabetes Mellitus: A Systematic Review, Zhila Semnani-Azad, Romy Gaillard, Alice E. Hughes, Kristen E. Boyle, Kristen E. Boyle, Deirdre K. Tobias, Paul W. Franks, Stephen S. Rich, Robert Wagner, Tina Vilsbøll, Kimberly K. Vesco, Miriam S. Udler, Tiinamaija Tuomi, Arianne Sweeting, Emily K. Sims, Jennifer L. Sherr, Robert K. Semple, Rebecca M. Reynolds, Maria J. Redondo, Leanne M. Redman, Richard E. Pratley, Rodica Pop-Busui, Toni I. Pollin, Wei Perng, Ewan R. Pearson, Susan E. Ozanne, Katharine R. Owen, Richard Oram, Rinki Murphy, Viswanathan Mohan, Shivani Misra, James B. Meigs, Nestoras Mathioudakis, Chantal Mathieu

Clinical Research Faculty Publications

Background: The objective of this systematic review is to identify prognostic factors among women and their offspring affected by gestational diabetes mellitus (GDM), focusing on endpoints of cardiovascular disease (CVD) and type 2 diabetes (T2D) for women, and cardiometabolic profile for offspring. Methods: This review included studies published in English language from January 1st, 1990, through September 30th, 2021, that focused on the above outcomes of interest with respect to sociodemographic factors, lifestyle and behavioral characteristics, traditional clinical traits, and ‘omics biomarkers in the mothers and offspring during the perinatal/postpartum periods and across the lifecourse. Studies that did not report …

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Trajectories Of Offending Over 9 Years After Youths' First Arrest: What Predicts Who Desists And Who Continues To Offend?, Elizabeth Cauffman, Jordan Beardslee, Colleen Sbeglia, Paul J. Frick, Laurence Steinberg Dec 2024

Trajectories Of Offending Over 9 Years After Youths' First Arrest: What Predicts Who Desists And Who Continues To Offend?, Elizabeth Cauffman, Jordan Beardslee, Colleen Sbeglia, Paul J. Frick, Laurence Steinberg

Faculty Publications

Antisocial and illegal behavior generally declines as youth approach adulthood, but there is significant individual variation in the timing of the peak and decline of offending from adolescence to young adulthood. There are two primary research questions in the present study. First, are there subgroups of youth who follow similar patterns of offending over the nine years after their first arrest? Second, what baseline factors predict which youth will follow each pattern of offending? Data were drawn from the Crossroads study, which includes a sample of racially and ethnically diverse boys who were interviewed regularly for 9 years following their …

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Shortened Sleep Duration Impairs Adipose Tissue Adrenergic Stimulation Of Lipolysis In Postmenopausal Women, Prachi Singh, Robbie A. Beyl, Jacqueline M. Stephens, Allison J. Richard, Anik Boudreau, R. Caitlin Hebert, Robert C. Noland, David H. Burk, Sujoy Ghosh, Jaroslaw Staszkiewicz, J. Michael Salbaum, Josiane L. Broussard, Marie Pierre St-Onge, Eric Ravussin, Kara L. Marlatt Dec 2024

Shortened Sleep Duration Impairs Adipose Tissue Adrenergic Stimulation Of Lipolysis In Postmenopausal Women, Prachi Singh, Robbie A. Beyl, Jacqueline M. Stephens, Allison J. Richard, Anik Boudreau, R. Caitlin Hebert, Robert C. Noland, David H. Burk, Sujoy Ghosh, Jaroslaw Staszkiewicz, J. Michael Salbaum, Josiane L. Broussard, Marie Pierre St-Onge, Eric Ravussin, Kara L. Marlatt

Division of Basic Science Faculty Publications

Objective: The objective of this study was to examine the changes in adipose tissue lipolytic capacity and insulin signaling in response to shortened sleep duration (SSD) in postmenopausal women. Methods: Adipose tissue from a randomized crossover study of nine healthy postmenopausal women (mean [SD], age: 59 [4] years; BMI: 28.0 [2.6] kg/m2) exposed to four nights of habitual and SSD (60% of habitual sleep) while following a eucaloric diet was examined ex vivo. Tissue lipolytic capacity was determined by measurement of secreted glycerol. Cellular insulin signaling was determined by measuring insulin-mediated changes in Akt phosphorylation. RNA sequencing examined global transcriptional …

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Exercise Therapy Rescues Skeletal Muscle Dysfunction And Exercise Intolerance In Cardiometabolic Hfpef, Heather Quiriarte, Robert C. Noland, James E. Stampley, Gregory Davis, Zhen Li, Eunhan Cho, Youyoung Kim, Jake Doiron, Guillaume Spielmann, Sujoy Ghosh, Sanjiv J. Shah, Brian A. Irving, David J. Lefer, Timothy D. Allerton Dec 2024

Exercise Therapy Rescues Skeletal Muscle Dysfunction And Exercise Intolerance In Cardiometabolic Hfpef, Heather Quiriarte, Robert C. Noland, James E. Stampley, Gregory Davis, Zhen Li, Eunhan Cho, Youyoung Kim, Jake Doiron, Guillaume Spielmann, Sujoy Ghosh, Sanjiv J. Shah, Brian A. Irving, David J. Lefer, Timothy D. Allerton

Division of Basic Science Faculty Publications

Exercise intolerance, a hallmark of heart failure with preserved ejection fraction (HFpEF) exacerbated by obesity, involves unclear mechanisms related to skeletal muscle metabolism. In a “2-hit” model of HFpEF, we investigated the ability of exercise therapy (voluntary wheel running) to reverse skeletal muscle dysfunction and exercise intolerance. Using state-of-the-art metabolic cages and a multiomic approach, we demonstrate exercise can rescue dysfunctional skeletal muscle lipid and branched-chain amino acid oxidation and restore exercise capacity in mice with cardiometabolic HFpEF. These results underscore the importance of skeletal muscle metabolism to improve exercise intolerance in HFpEF.

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Nest Box-Mounted Pit Tag Readers Reveal Cryptic Recruits Of Cavity-Nesting Waterfowl In South Louisiana, Katie E. Miranda, Kevin M. Ringelman, Dylan L. Bakner Dec 2024

Nest Box-Mounted Pit Tag Readers Reveal Cryptic Recruits Of Cavity-Nesting Waterfowl In South Louisiana, Katie E. Miranda, Kevin M. Ringelman, Dylan L. Bakner

Faculty Publications

Black-bellied Whistling-Ducks (Dendrocygna autumnalis; BBWD) are rapidly expanding northward into the core range of the eastern Wood Duck (Aix sponsa; WODU), yet little is known about BBWD nesting ecology. Typical field methods to study cavity-nesting waterfowl (i.e., weekly nest monitoring) preclude a full understanding of important breeding information, including nest prospecting and parasitic egg laying. To address this, we used subcutaneous passive integrated transponder (PIT) tags embedded in adults and PIT tag readers mounted on nest boxes with the objective to (1) identify individuals that used nest boxes but were not physically captured on a nest, (2) quantify box visitation, …

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The Impact Of Exercise On Gene Regulation In Association With Complex Trait Genetics, Nikolai G. Vetr, Nicole R. Gay, Joshua N. Adkins, Brent G. Albertson, David Amar, Mary Anne S. Amper, Jose Juan Almagro Armenteros, Euan Ashley, Julian Avila-Pacheco, Dam Bae, Ali Tugrul Balci, Marcas Bamman, Nasim Bararpour, Elisabeth R. Barton, Pierre M. Jean Beltran, Bryan C. Bergman, Daniel H. Bessesen, Sue C. Bodine, Frank W. Booth, Brian Bouverat, Thomas W. Buford, Charles F. Burant, Tiziana Caputo, Steven Carr, Toby L. Chambers, Clarisa Chavez, Maria Chikina, Roxanne Chiu, Michael Cicha, Clary B. Clish, Paul M. Coen, Dan Cooper, Elaine Cornell, Gary Cutter Dec 2024

The Impact Of Exercise On Gene Regulation In Association With Complex Trait Genetics, Nikolai G. Vetr, Nicole R. Gay, Joshua N. Adkins, Brent G. Albertson, David Amar, Mary Anne S. Amper, Jose Juan Almagro Armenteros, Euan Ashley, Julian Avila-Pacheco, Dam Bae, Ali Tugrul Balci, Marcas Bamman, Nasim Bararpour, Elisabeth R. Barton, Pierre M. Jean Beltran, Bryan C. Bergman, Daniel H. Bessesen, Sue C. Bodine, Frank W. Booth, Brian Bouverat, Thomas W. Buford, Charles F. Burant, Tiziana Caputo, Steven Carr, Toby L. Chambers, Clarisa Chavez, Maria Chikina, Roxanne Chiu, Michael Cicha, Clary B. Clish, Paul M. Coen, Dan Cooper, Elaine Cornell, Gary Cutter

Clinical Research Faculty Publications

Endurance exercise training is known to reduce risk for a range of complex diseases. However, the molecular basis of this effect has been challenging to study and largely restricted to analyses of either few or easily biopsied tissues. Extensive transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium has provided a unique opportunity to clarify how exercise can affect tissue-specific gene expression and further suggest how exercise adaptation may impact complex disease-associated genes. To build this map, we integrate this multi-tissue atlas of gene expression changes with gene-disease …

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Children’S Individual Differences In The Responses To A New Method For Physical Education, Sara Pereira, Carla Santos, José Maia, Olga Vasconcelos, Eduardo Guimarães, Rui Garganta, Cláudio Farias, Tiago V. Barreira, Go Tani, Peter T. Katzmarzyk, Fernando Garbeloto Dec 2024

Children’S Individual Differences In The Responses To A New Method For Physical Education, Sara Pereira, Carla Santos, José Maia, Olga Vasconcelos, Eduardo Guimarães, Rui Garganta, Cláudio Farias, Tiago V. Barreira, Go Tani, Peter T. Katzmarzyk, Fernando Garbeloto

Population and Public Health Science Faculty Publications

Children’s fundamental movement skills (FMS) require planned and guided interventions to develop appropriately. We investigated the effect of a novel Physical Education (PE) method to develop children’s object control, locomotor skills, and motor competence. Further, we examined children’s trainability, i.e., their differential responses to the new method, and identified low and high responders to the intervention. The study lasted three months and included six to seven-year-old children in two groups: control (the current, official PE program; n = 38) and experimental (the new method; n = 52). Twelve FMS [object control (OC), locomotor (LO)] were reliably assessed using the Meu …

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Sex Differences In Interacting Genetic And Functional Connectivity Biomarkers In Alzheimer’S Disease, Jordan N. Williamson, Shirley A. James, Sean P. Mullen, Bradley P. Sutton, Tracey Wszalek, Beni Mulyana, Peter Mukli, Andriy Yabluchanskiy, Balebail Ashok Raj, Kristin Fargher, Amanda Smith, Lisa Raudin, Gloria Chaing, Norman Relkin, Karen Elizabeth Smith, Hyungsub Shim, Laura L.Boles Ponto, Susan K. Schultz, Antero Sarrael, Raymundo Hernando, Nunzio Pomara, Dick Drost, Andrew Kertesz, John Rogers, Irina Rachinsky, Stephen Pasternak, Elizabether Finger, David Bachman, Kenneth Spicer, Jacobo Mintzer, Bruce L. Miller, Howard J. Rosen, Stephen Correia, Paul Malloy Dec 2024

Sex Differences In Interacting Genetic And Functional Connectivity Biomarkers In Alzheimer’S Disease, Jordan N. Williamson, Shirley A. James, Sean P. Mullen, Bradley P. Sutton, Tracey Wszalek, Beni Mulyana, Peter Mukli, Andriy Yabluchanskiy, Balebail Ashok Raj, Kristin Fargher, Amanda Smith, Lisa Raudin, Gloria Chaing, Norman Relkin, Karen Elizabeth Smith, Hyungsub Shim, Laura L.Boles Ponto, Susan K. Schultz, Antero Sarrael, Raymundo Hernando, Nunzio Pomara, Dick Drost, Andrew Kertesz, John Rogers, Irina Rachinsky, Stephen Pasternak, Elizabether Finger, David Bachman, Kenneth Spicer, Jacobo Mintzer, Bruce L. Miller, Howard J. Rosen, Stephen Correia, Paul Malloy

Clinical Research Faculty Publications

As of 2023, it is estimated that 6.7 million individuals in the United States live with Alzheimer’s disease (AD). Prior research indicates that AD disproportionality affects females; females have a greater incidence rate, perform worse on a variety of neuropsychological tasks, and have greater total brain atrophy. Recent research shows that hippocampal functional connectivity differs by sex and may be related to the observed sex differences in AD, and apolipoprotein E (ApoE) ε4 carriers have reduced hippocampal functional connectivity. The purpose of this study was to determine if the ApoE genotype plays a role in the observed sex differences in …

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Blood And Mri Biomarkers Of Mild Traumatic Brain Injury In Non-Concussed Collegiate Football Players, Eunhan Cho, Joshua Granger, Bailey Theall, Nathan Lemoine, Derek Calvert, Jack Marucci, Shelly Mullenix, Hollis O’Neal, Tomas Jacome, Brian A. Irving, Neil M. Johannsen, Owen Carmichael, Guillaume Spielmann Dec 2024

Blood And Mri Biomarkers Of Mild Traumatic Brain Injury In Non-Concussed Collegiate Football Players, Eunhan Cho, Joshua Granger, Bailey Theall, Nathan Lemoine, Derek Calvert, Jack Marucci, Shelly Mullenix, Hollis O’Neal, Tomas Jacome, Brian A. Irving, Neil M. Johannsen, Owen Carmichael, Guillaume Spielmann

Clinical Research Faculty Publications

Football has one of the highest incidence rates of mild traumatic brain injury (mTBI) among contact sports; however, the effects of repeated sub-concussive head impacts on brain structure and function remain under-studied. We assessed the association between biomarkers of mTBI and structural and functional MRI scans over an entire season among non-concussed NCAA Division I linemen and non-linemen. Concentrations of S100B, GFAP, BDNF, NFL, and NSE were assessed in 48 collegiate football players (32 linemen; 16 non-linemen) before the start of pre-season training (pre-camp), at the end of pre-season training (pre-season), and at the end of the competitive season (post-season). …

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Evidence For A Shock-Compressed Magnetic Field In The Northwestern Rim Of Vela Jr. From X-Ray Polarimetry, Dmitry A. Prokhorov, Yi Jung Yang, Riccardo Ferrazzoli, Jacco Vink, Patrick Slane, Enrico Costa, Stefano Silvestri, Ping Zhou, Niccolò Bucciantini, Alessandro Di Marco, Martin C. Weisskopf, Luca Baldini, Victor Doroshenko, Steven R. Ehlert, Jeremy Heyl, Philip Kaaret, Dawoon E. Kim, Frédéric Marin, Tsunefumi Mizuno, Chi Yung Ng, Melissa Pesce-Rollins, Carmelo Sgrò, Paolo Soffitta, Douglas A. Swartz, Toru Tamagawa, Fei Xie, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno Dec 2024

Evidence For A Shock-Compressed Magnetic Field In The Northwestern Rim Of Vela Jr. From X-Ray Polarimetry, Dmitry A. Prokhorov, Yi Jung Yang, Riccardo Ferrazzoli, Jacco Vink, Patrick Slane, Enrico Costa, Stefano Silvestri, Ping Zhou, Niccolò Bucciantini, Alessandro Di Marco, Martin C. Weisskopf, Luca Baldini, Victor Doroshenko, Steven R. Ehlert, Jeremy Heyl, Philip Kaaret, Dawoon E. Kim, Frédéric Marin, Tsunefumi Mizuno, Chi Yung Ng, Melissa Pesce-Rollins, Carmelo Sgrò, Paolo Soffitta, Douglas A. Swartz, Toru Tamagawa, Fei Xie, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno

Faculty Publications

Synchrotron X-ray emission has been detected from nearly a dozen young supernova remnants (SNRs). X-rays of synchrotron origin exhibit linear polarization in a regular, non-randomly oriented magnetic field. The significant polarized X-ray emission from four such SNRs has already been reported on the basis of observations with the Imaging X-ray Polarimetry Explorer (IXPE). The magnetic-field structure as derived from IXPE observations is radial for Cassiopeia A, Tycho's SNR, and SN 1006, and tangential for RX J1713.7-3946. The latter together with the recent detection of a tangential magnetic field in SNR 1E 0102.2-7219 by the Australia Telescope Compact Array in the …

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-Decay Half-Life Predictions With Support Vector Machine, Amir Jalili, Feng Pan, Jerry P. Draayer, Ai Xi Chen, Zhongzhou Ren Dec 2024

-Decay Half-Life Predictions With Support Vector Machine, Amir Jalili, Feng Pan, Jerry P. Draayer, Ai Xi Chen, Zhongzhou Ren

Faculty Publications

In this study, we investigate the application of support vector machines utilizing a radial basis function kernel for predicting nuclear -decay half-lives. Our approach integrates a comprehensive set of physics-derived features, including characteristics derived from nuclear structure, to systematically evaluate their impact on predictive accuracy. In addition to traditional parameters such as proton and neutron numbers, as well as terms based on the liquid drop model (e.g., volume, surface, Coulomb features), we incorporate decay energies and orbital angular momentum quantum numbers for both parent and daughter nuclei. Our analysis of 2232 nuclear data points demonstrates that the use of the …

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Uncertainty Quantification Of Collective Nuclear Observables From The Chiral Potential Parametrization, Kevin S. Becker, Kristina D. Launey, Andreas Ekström, Tomáš Dytrych, Daniel Langr, Grigor H. Sargsyan, Jerry P. Draayer Dec 2024

Uncertainty Quantification Of Collective Nuclear Observables From The Chiral Potential Parametrization, Kevin S. Becker, Kristina D. Launey, Andreas Ekström, Tomáš Dytrych, Daniel Langr, Grigor H. Sargsyan, Jerry P. Draayer

Faculty Publications

We perform an uncertainty estimate of quadrupole moments and B(E2) transition rates that inform nuclear collectivity. In particular, we study the low-lying states of 6Li and 12C using the ab initio symmetry-adapted no-core-shell model. For a narrow standard deviation of approximately 1% on the low-energy constants which parametrize high-precision chiral potentials, we find output standard deviations in the collective observables ranging from approximately 3%-6%. The results mark the first step towards a rigorous uncertainty quantification of collectivity in nuclei that aims to account for all sources of uncertainty in ab initio descriptions of challenging collective and clustering observables.

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