Digital Commons Network^™

Exploring The Interconnectivity Between Soilless Substrate Hydraulic Properties And Plant Root Morphology, Kristopher S. Criscione

LSU Doctoral Dissertations

Horticultural container production heavily relies upon porous soilless substrates to mass produce specialty crops. Soilless substrates are responsible for continuously maintaining optimal water, mineral nutrients, and air balances to promote healthy root growth and support productive shoot yield (foliage or fruit). Increasing evidence of substrate research continues to highlight the strong relationships associated with root development and substrate physiochemical properties. Despite the importance of the root system for overall plant health, most horticultural research to-date has focused on shoot development. Research tends to report total root biomass as the primary root-growth metric; however, this results in several developmental features becoming …

Multiscale & Multiphysics Model Of Damage In Lithium-Ion Batteries, Edris Akbari

LSU Doctoral Dissertations

The demand for safer and more reliable lithium-ion batteries (LIBs) in electric vehicles has increased significantly, especially in addressing mechanical failures like internal short circuits (ISCs), which can lead to thermal runaway. This research investigates the mechanical behavior and damage mechanisms in lithium-ion pouch cells through a multiscale and multiphysics approach, focusing on Lithium Nickel Manganese Cobalt Oxide (NMC) and Lithium Iron Phosphate (LFP) batteries.

The study involved quasi-static and dynamic mechanical tests, including indentation and high-speed penetration, to evaluate stress-strain responses and fracture behaviors. Anisotropic mechanical properties were measured for individual battery components (anode, cathode, separator, and shell) using …

Advancing Data-Driven Disaster Debris Characterization And Quantification, Jasmine Bekkaye

LSU Doctoral Dissertations

Natural hazards generate tremendous amounts of debris that negatively impact communities and overwhelm waste management infrastructure. The challenge in disaster debris planning and management stems from inconsistent and scarce post-disaster debris quantity data due to the chaotic nature of recovery operations. This leads to a limited understanding of key factors influencing disaster debris generation across hazards and regions, hindering the accuracy and efficiency of modeling. With the increasing availability of comprehensive post-disaster waste datasets, the capacity to understand debris generation is expanding. This dissertation aims to fill knowledge gaps on disaster debris generation as follows: (1) investigate existing technologies for …

Coastal Wetlands In The Anthropocene, John Day, Edward Anthony, Robert Costanza, Douglas Edmonds, Joel Gunn, Charles Hopkinson, Michael E. Mann, James Morris, Michael Osland, Tracy Quirk, Andre Rovai, John Rybczyk, Thomas Spencer, Jessica Stephens, Jaia Syvitski, Robert Twilley, Jenneke Visser, John R. White

Faculty Publications

We review the functioning and sustainability of coastal marshes and mangroves. Urbanized humans have a 7,000-year-old enduring relationship to coastal wetlands. Wetlands include marshes, salt flats, and saline and freshwater forests. Coastal wetlands occur in all climate zones but are most abundant in deltas. Mangroves are tropical, whereas marshes occur from tropical to boreal areas. Quantification of coastal wetland areas has advanced in recent years but is still insufficiently accurate. Climate change and sea-level rise are predicted to lead to significant wetland losses and other impacts on coastal wetlands and the humans associated with them. Landward migration and coastal retreat …

Effect Of Electronegativity On Environmentally Persistent Free Radical (Epfr) Formation, Persistence, And Toxicity On Transition Metal Oxides, Syed Monjur Ahmed

LSU Doctoral Dissertations

Environmentally persistent free radicals (EPFRs) are a group of emerging environmental pollutants. Owing to their resonance structures, EPFRs have significantly higher lifetimes than typical free radicals, and can induce the formation of reactive oxygen species (ROS) known to cause pulmonary and cardiovascular dysfunction. EPFRs form by the adsorption of organic precursors on a transition metal oxide (TMO) surface and exhibit enough stability to cause negative health and environmental effects. While aromatic and substituted aromatic precursors form EPFRs on TMO surface at elevated temperatures and numerous substituted organics are ubiquitous in various industrial processes and household products, studies have largely overlooked …

Rootzone Soil Moisture Dynamics Using Terrestrial Water-Energy Coupling, Vinit Sehgal, Binayak P. Mohanty, Rolf H. Reichle

Faculty Publications

A lack of high-density rootzone soil moisture (θRZ) observations limits the estimation of continental-scale, space-time contiguous θRZ dynamics. We derive a proxy of daily θRZ dynamics — active rootzone degree of saturation (SRZ) — by recursive low-pass (LP) filtering of surface soil moisture (θS) within a terrestrial water-energy coupling (WEC) framework. We estimate the LP filter parameters and WEC thresholds for the piecewise-linear coupling between SRZ and evaporative fraction (EF) at remote sensing and field scale over the Contiguous U.S. We use θS from the Soil Moisture Active-Passive (SMAP) satellite and 218 in-situ stations, with EF from the Moderate Resolution …

Development And Evaluation Of A Colorimetric Lamp Based-Assay Targeting The Bacteroides Hf183 Marker For Tracking Sewage Pollution In Environmental Waters, Mariah C.A. Do Nascimento, Wendy J.M. Smith, Metasebia Gebrewold, Yawen Liu, Stuart L. Simpson, Aaron Bivins, Paula Rahal, Warish Ahmed

Faculty Publications

Surface waters are vulnerable to contamination by human and animal feces, posing risks to human health due to potential exposure to enteric pathogens. This research developed a colorimetric loop-mediated isothermal amplification (cLAMP) assay to detect sewage associated Bacteroides dorei HF183/BacR287 (HF183) marker in wastewater and environmental water samples. The host sensitivity and host specificity of the assay were evaluated, and their performance was compared to the Bacteroides HF183 qPCR assay using control materials (gBlocks), environmental water samples seeded with untreated sewage, and ambient environmental water samples. In serial dilutions of control materials, qPCR produced quantifiable data across all dilutions, while …

Financial Impacts Of 2020 Labor Day Wildfires To Oregon Highways, Kevin Christiansen, Rubayet Bin Mostafiz, Ayat Al Assi, Robert V. Rohli, Carol J. Friedland

Faculty Publications

Wildfire-caused damage to highways has a significant financial cost to the local, regional, and state jurisdictions where they occur. This study examines the financial ramifications of the harm caused to highways by megafires, using a case study of the highways impacted in the U.S. state of Oregon by the five megafires that occurred during the 2020 Labor Day wildfires. This study proposes a method to classify financial road damage from these wildfires based upon curated datasets collected from the Oregon Department of Transportation (ODOT). Hence, this study presents a dataset with labeled classes, which include physical, roadway, and traffic. Physical …

On The Pathogenesis Of Obesity: Causal Models And Missing Pieces Of The Puzzle, Faidon Magkos, Thorkild I.A. Sørensen, David Raubenheimer, Nikhil V. Dhurandhar, Ruth J.F. Loos, Anja Bosy-Westphal, Christoffer Clemmensen, Mads F. Hjorth, David B. Allison, Gary Taubes, Eric Ravussin, Mark I. Friedman, Kevin D. Hall, David S. Ludwig, John R. Speakman, Arne Astrup

Clinical Research Faculty Publications

Application of the physical laws of energy and mass conservation at the whole-body level is not necessarily informative about causal mechanisms of weight gain and the development of obesity. The energy balance model (EBM) and the carbohydrate–insulin model (CIM) are two plausible theories, among several others, attempting to explain why obesity develops within an overall common physiological framework of regulation of human energy metabolism. These models have been used to explain the pathogenesis of obesity in individuals as well as the dramatic increases in the prevalence of obesity worldwide over the past half century. Here, we summarize outcomes of a …

Precision Interventions Targeting The Maternal Metabolic Milieu For Healthy Pregnancies In Obesity, Alexandra M. Niclou, Hannah E. Cabre, Emily W. Flanagan, Leanne M. Redman

Clinical Research Faculty Publications

Purpose of Review: Entering pregnancy with obesity increases the risk of adverse health outcomes for parent and child. As such, research interventions are largely focused on limiting excess gestational weight gain during pregnancy, especially in those with obesity. Yet, while many lifestyle interventions are successful in reducing GWG, few affect pregnancy outcomes. Here we review work targeting the metabolic milieu instead of focusing solely on weight. Recent Findings: Work done in non-pregnant populations suggests that specifically targeting glucose, triglyceride, and leptin levels or inflammatory makers improves the metabolic milieu and overall health. We posit that precision interventions that include strategies …

Brain Insulin Signaling Is Associated With Late-Life Cognitive Decline, Han Tong, Ana W. Capuano, Owen T. Carmichael, Kathryn L. Gwizdala, David A. Bennett, Rexford S. Ahima, Steven E. Arnold, Zoe Arvanitakis

Clinical Research Faculty Publications

Type-2 diabetes is associated with an increased risk of dementia, and the underlying mechanism might involve abnormal insulin signaling in the brain. The objective of this study was to examine the association of postmortem brain insulin signaling with late-life cognitive decline. Among participants of Religious Orders Study, a community-based clinical-pathological cohort, 150 deceased and autopsied older individuals (75 with diabetes matched to 75 without by age at death, sex, and education) had postmortem brain insulin signaling measurements collected in the prefrontal cortex using ELISA and immunohistochemistry. By using adjusted linear mixed-effects models, we examined the association of postmortem brain insulin …

A Quantitative Adverse Outcome Pathway For Embryonic Activation Of The Aryl Hydrocarbon Receptor Of Fishes By Polycyclic Aromatic Hydrocarbons Leading To Decreased Fecundity At Adulthood, Jon A. Doering, Justin Dubiel, Eric Stock, Cameron H. Collins, Ian Frick, Hunter M. Johnson, Christopher M. Lowrey-Dufour, Justin G.P. Miller, Zhe Xia, Gregg T. Tomy, Steve Wiseman

Faculty Publications

Quantitative adverse outcome pathways (qAOPs) describe the response–response relationships that link the magnitude and/or duration of chemical interaction with a specific molecular target to the probability and/or severity of the resulting apical-level toxicity of regulatory relevance. The present study developed the first qAOP for latent toxicities showing that early life exposure adversely affects health at adulthood. Specifically, a qAOP for embryonic activation of the aryl hydrocarbon receptor 2 (AHR2) of fishes by polycyclic aromatic hydrocarbons (PAHs) leading to decreased fecundity of females at adulthood was developed by building on existing qAOPs for (1) activation of the AHR leading to early …

Prescribed Fire Regimes Influence Responses Of Fungal And Bacterial Communities On New Litter Substrates In A Brackish Tidal Marsh, Viet Q. Dao, Crystal N. Johnson, William J. Platt

Faculty Publications

Processes modifying newly deposited litter substrates should affect fine fuels in fire-managed tidal marsh ecosystems. Differences in chemical composition and dynamics of litter should arise from fire histories that generate pyrodiverse plant communities, tropical cyclones that deposit wrack as litter, tidal inundation that introduces and alters sediments and microbes, and interactions among these different processes. The resulting diversity and dynamics of available litter compounds should affect microbial (fungal and bacterial) communities and their roles in litter substrate dynamics and ecosystem responses over time. We experimentally examined effects of differences in litter types produced by different fire regimes and litter loads …

Comparative Transcriptomic Analyses Reveal Differences In The Responses Of Diploid And Triploid Eastern Oysters To Environmental Stress, Rujuta V Vaidya, Sarah Bodenstein, Dildorakhon Rasulova, Jerome F La Peyre, Morgan W Kelly

Faculty Publications

Triploid oysters are commonly used as the basis for production in the aquaculture of eastern oysters along the USA East and Gulf of Mexico coasts. While they are valued for their rapid growth, incidents of triploid mortality during summer months have been well documented in eastern oysters, especially at low salinity sites. We compared global transcriptomic responses of diploid and triploid oysters bred from the same three maternal source populations at two different hatcheries and outplanted to a high (annual mean salinity = 19.4 ± 6.7) and low (annual mean salinity = 9.3 ± 5.0) salinity site. Oysters were sampled …

Fall 2024 Catalog, Lsu Press

LSU Press Seasonal Catalogs

No abstract provided.

Bipolar Membrane Capacitive Deionization For The Selective Capture Of Lithium Ions From Brines And Conversion To Lithium Hydroxide, Tanmay Kulkarni, Aliya Muhammad I. Al Dhamen, Xiaoliu Zhang, Chan Wen Chiu, Hanrui Zhang, Feifei Shi, Revati Kumar, Christopher G. Arges

Faculty Publications

Meeting the increasing demand for lithium in vehicle electrification and renewable energy storage requires innovations in lithium-ion (Li⁺) separations. Traditional solar evaporation methods for lithium recovery are slow and consume tremendous volumes of water and secondary chemicals (acids and bases). This study introduces a bipolar membrane capacitive deionization (BPM-CDI) unit for direct lithium extraction and LiOH production without the external addition of acids and bases. Utilizing de-lithiated lithium-iron-phosphate (LFP) coated carbon cloth electrodes, the BPM-CDI unit demonstrates selective Li⁺ capture over competing ions. Molecular dynamics simulations and H-cell experiments elucidate pH inversion mechanisms during Li⁺ release, …

Spatiotemporal Climatology Of Georgia Tropical Cyclones And Associated Rainfall, Reilly Corkran, Jill Trepanier, Vincent Brown

Faculty Publications

Tropical cyclones (TCs), often characterized by high wind speeds and heavy rainfall, cause widespread devastation, affecting millions of people and leading to economic losses worldwide. TC-specific research in Georgia is scarce, likely due to the minimal geographical extent of its coast and the infrequency of direct landfalls. Research on Georgia TCs does not account for storms that make landfall in other southeastern states (e.g., Florida) and continue north, northeast, or northwest into Georgia. This study used the North Atlantic Basin hurricane database (HURDAT2) to quantify the spatiotemporal patterns of direct and indirect landfalling of Georgia tropical cyclones (>16 ms−1) …

Scene Classification Of Remote Sensing Image Based On Multi-Path Reconfigurable Neural Network, Wenyi Hu, Chunjie Lan, Tian Chen, Shan Liu, Lirong Yin, Lei Wang

Faculty Publications

Land image recognition and classification and land environment detection are important research fields in remote sensing applications. Because of the diversity and complexity of different tasks of land environment recognition and classification, it is difficult for researchers to use a single model to achieve the best performance in scene classification of multiple remote sensing land images. Therefore, to determine which model is the best for the current recognition classification tasks, it is often necessary to select and experiment with many different models. However, finding the optimal model is accompanied by an increase in trial-and-error costs and is a waste of …

Scaling The Polymerization Of Polyaldehydes Through Continuous Flow Synthesis, Jared M. Schwartz, Paul A. Kohl, Anthony Engler

Faculty Publications

A plug flow reactor was constructed to scale the synthesis of metastable, phthalaldehyde-based polymers to achieve production rates of 1–2 kg per day. The flow-induced mixing and in-line polymerization quench and precipitation sequences resulted in improved polymer purity and long-term stability compared to the same materials made from a conventional batch process. Cryogenic rheology was used to probe the complex fluid dynamics encountered during the polymerization of PPA homopolymers. It is envisioned that this continuous flow manufacturing approach could be extended to other low ceiling temperature or aldehyde monomer systems to help implement and support a plastic circular economy. Graphical …

Technician Assignment In Multi-Shift Maintenance Schedules In An Offshore Wind Farm, Md Imran Hasan Tusar, Bhaba R. Sarker

Faculty Publications

Offshore wind farms are becoming more and more important to sustainable energy strategies, yet their maintenance presents unique logistical challenges. The focus of this research is the Technician Assignment Problem (TAP) which involves a complicated and fluctuating scheduling problem. The key objective is to determine the most effective assignment of technicians to maintenance tasks to maximize operational efficiency and ensure reliable service. This study introduces a mathematical optimization model that processes numerous variables—technician availability, skill sets, and temporal constraints—to minimize unmet maintenance needs and ensure equitable workload distribution. The model is based on assumptions derived from actual operational conditions and …

Machine Learning For Automated Classification Of Lung Collagen In A Urethane-Induced Lung Injury Mouse Model, Khalid Hamad Alnafisah, Amit Ranjan, Sushant P. Sahu, Jianhua Chen, Sarah Mohammad Alhejji, Alexandra Noël, Manas Ranjan Gartia, Supratik Mukhopadhyay

Faculty Publications

Dysregulation of lung tissue collagen level plays a vital role in understanding how lung diseases progress. However, traditional scoring methods rely on manual histopathological examination introducing subjectivity and inconsistency into the assessment process. These methods are further hampered by inter-observer variability, lack of quantification, and their time-consuming nature. To mitigate these drawbacks, we propose a machine learning-driven framework for automated scoring of lung collagen content. Our study begins with the collection of a lung slide image dataset from adult female mice using second harmonic generation (SHG) microscopy. In our proposed approach, first, we manually extracted features based on the 46 …

Sustainability Of Asphalt Mixtures Containing 50% Rap And Recycling Agents, Ibrahim Elnaml, Louay N. Mohammad, Gaylon Baumgardner, Samuel Cooper, Samuel Cooper

Faculty Publications

The substitution of virgin asphalt binder with reclaimed asphalt pavement (RAP) has environmental and economic merits, however, cracking susceptibility arises due to the aged asphalt binder within RAP. The objectives of this study are to (1) enhance the cracking resistance of asphalt mixtures containing 50% RAP utilizing recycling agents (RAs) derived from six petroleum-based and bio-based materials, (2) conduct an environmental impact assessment (represented by global warming potential “GWP”) for high-RAP mixtures including RAs, and (3) estimate the cost effectiveness of including high-RAP content in asphalt mixtures. Based on the RAP asphalt binder performance grade (PG), base asphalt binder PG, …

Lignin Cationization For The Removal Of Phosphates And Nitrates From Effluents Of Wastewater Treatment Plants, Fannyuy V. Kewir, Carlos E. Astete, Divine B. Nde, Jessica R. Eberhard, W. David Constant, Cristina M. Sabliov

Faculty Publications

The removal of phosphates and nitrates from wastewater treatment plant (WWTP) effluents is important for preventing pollution of receiving waters. In this study, we chemically modified alkaline lignin (aLN) with quaternary ammonium groups to obtain biodegradable cationic lignin (cLN). We characterized the cLN and tested its efficacy for removing phosphates and nitrates in a lab setting and on field-collected WWTP samples. Adsorption isotherm and kinetic studies were performed in aqueous media, and the effects of several variables (contact time, pH, initial concentration, and adsorbent dose) were investigated. The Langmuir isotherm described phosphate and nitrate adsorption well, with R2 values of …

Prevailing Issues And Actions In Urban Best Practices Across Latin America And The Caribbean, Fabio Capra-Ribeiro

Faculty Publications

This research examines urban best practices (BPs) across Latin America and the Caribbean to illuminate the prevalent issues and actions associated with these locally implemented initiatives. An analysis of 45 BPs from the UN-Habitat repository was conducted using both quantitative and qualitative methods, organized into three phases. The first phase focused on collecting data such as BP sources, countries of origin, and years of implementation. The second phase identified common problems and actions within the BPs. The third phase involved a cross-sectional analysis to identify significant patterns and trends. The study found that many BPs originated from the Dubai International …

Formation And Microwave Losses Of Hydrides In Superconducting Niobium Thin Films Resulting From Fluoride Chemical Processing, Carlos G. Torres-Castanedo, Dominic P. Goronzy, Thang Pham, Anthony Mcfadden, Nicholas Materise, Paul Masih Das, Matthew Cheng, Dmitry Lebedev, Stephanie M. Ribet, Mitchell J. Walker, David A. Garcia-Wetten, Cameron J. Kopas, Jayss Marshall, Ella Lachman, Nikolay Zhelev, James A. Sauls, Joshua Y. Mutus, Corey Rae H. Mcrae, Vinayak P. Dravid, Michael J. Bedzyk, Mark C. Hersam

Faculty Publications

Superconducting niobium (Nb) thin films have recently attracted significant attention due to their utility for quantum information technologies. In the processing of Nb thin films, fluoride-based chemical etchants are commonly used to remove surface oxides that are known to affect superconducting quantum devices adversely. However, these same etchants can also introduce hydrogen to form Nb hydrides, potentially negatively impacting microwave loss performance. Here, comprehensive materials characterization of Nb hydrides formed in Nb thin films as a function of fluoride chemical treatments is presented. In particular, secondary-ion mass spectrometry, X-ray scattering, and transmission electron microscopy reveal the spatial distribution and phase …

The Past And Future Of The Fisheries And Marine Ecosystem Model Intercomparison Project, Camilla Novaglio, Andrea Bryndum-Buchholz, Derek P. Tittensor, Tyler D. Eddy, Heike K. Lotze, Cheryl S. Harrison, Ryan F. Heneghan, Olivier Maury, Kelly Ortega-Cisneros, Colleen M. Petrik, Kelsey E. Roberts, Julia L. Blanchard

Faculty Publications

Climate change is increasingly affecting the world's ocean ecosystems, necessitating urgent guidance on adaptation strategies to limit or prevent catastrophic impacts. The Fisheries and Marine Ecosystem Model Intercomparison Project (FishMIP) is a network and framework that provides standardised ensemble projections of the impacts of climate change and fisheries on ocean life and the benefits that it provides to people. Since its official launch in 2013 as a small, self-organized project within the larger Inter-Sectoral Impact Model Intercomparison Project, the FishMIP community has grown substantially and contributed to key international policy processes, such as the Intergovernmental Panel on Climate Change Assessment …

Evaluation Of Industrial And Consumer 3-D Resin Printer Fabrication Of Microdevices For Quality Management Of Genetic Resources In Aquatic Species, Seyedmajid Hosseini, Jack C. Koch, Yue Liu, Ignatius Semmes, Isabelina Nahmens, W. Todd Monroe, Jian Xu, Terrence R. Tiersch

Faculty Publications

Aquatic germplasm repositories can play a pivotal role in securing the genetic diversity of natural populations and agriculturally important aquatic species. However, existing technologies for repository development and operation face challenges in terms of accuracy, precision, efficiency, and cost-effectiveness, especially for microdevices used in gamete quality evaluation. Quality management is critical throughout genetic resource protection processes from sample collection to final usage. In this study, we examined the potential of using three-dimensional (3-D) stereolithography resin printing to address these challenges and evaluated the overall capabilities and limitations of a representative industrial 3-D resin printer with a price of US$18,000, a …

Esrra Regulates Rplp1-Mediated Translation Of Lysosome Proteins Suppressed In Metabolic Dysfunction-Associated Steatohepatitis And Reversed By Alternate Day Fasting, Madhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, Jin Zhou, Priyanka Guptta, Suganya Sakthivel, Wei Wen Teo, Yadanar Than Naing, Kabilesh Arul, Keziah Tikno, Sung Hee Park, Yajun Wu, Lijin Wang, Boon Huat Bay, Lei Sun, Vincent Giguere, Pierce K.H. Chow, Sujoy Ghosh, Donald P. Mcdonnell, Paul M. Yen, Brijesh K. Singh

Division of Basic Science Faculty Publications

Objective: Currently, little is known about the mechanism(s) regulating global and specific protein translation during metabolic dysfunction-associated steatohepatitis (MASH; previously known as non-alcoholic steatohepatitis, NASH). Methods: Unbiased label-free quantitative proteome, puromycin-labelling and polysome profiling were used to understand protein translation activity in vitro and in vivo. Results: We observed a global decrease in protein translation during lipotoxicity in human primary hepatocytes, mouse hepatic AML12 cells, and livers from a dietary mouse model of MASH. Interestingly, proteomic analysis showed that Rplp1, which regulates ribosome and translation pathways, was one of the most downregulated proteins. Moreover, decreased Esrra expression and binding to …

Effect Of Impaired Awareness Of Hypoglycemia On Glucose Decline During And After Exercise In The T1dexi Study, Jorge L. Jo Kamimoto, Zoey Li, Robin L. Gal, Jessica R. Castle, Francis J. Doyle, Peter G. Jacobs, Corby K. Martin, Roy W. Beck, Peter Calhoun, Michael C. Riddell, Michael R. Rickels

Clinical Research Faculty Publications

Context: Adults with type 1 diabetes (T1D) face the necessity of balancing the benefits of exercise with the potential hazards of hypoglycemia. Objective: This work aimed to assess whether impaired awareness of hypoglycemia (IAH) affects exercise-associated hypoglycemia in adults with T1D. Methods: We compared continuous glucose monitoring (CGM)-measured glucose during exercise and for 24 hours following exercise from 95 adults with T1D and IAH (Clarke score ≥4 or ≥1 severe hypoglycemic event within the past year) to 95 “aware” adults (Clarke score ≤2 and no severe hypoglycemic event within the past year) matched on sex, age, insulin delivery modality, and …

Far From Their Origins: A Transcriptomic Investigation On How 2,4-Di-Tert-Butyl-6-(5-Chloro-2h-Benzotriazol-2-Yl) Phenol Affects Rainbow Trout Alevins, Andreas N.M. Eriksson, Justin Dubiel, Alper James Alcaraz, Jon A. Doering, Steve Wiseman

Faculty Publications

Benzotriazole ultraviolet stabilizers (BUVSs) are a group of widely used chemicals added to a variety of consumer (e.g., plastics) and industrial (e.g., metal coating) goods. Although detected globally as an environmentally persistent pollutant, BUVSs have received relatively little toxicological attention and only recently have been acknowledged to affect development and the endocrine system in vivo. In our previous study, altered behavior, indicative of potential neurotoxicity, was observed among rainbow trout alevins (day 14 posthatching) that were microinjected as embryos with a single environmentally relevant dose of 2,4-di-tert-butyl–6-(5-chloro-2H-benzotriazol-2-yl) phenol (UV-327). In the present follow-up study, we performed whole-transcriptome profiling (RNA sequencing) …