Digital Commons Network^™

Nearly-Lossless-To-Lossy Medical Image Compression By The Optimized Jpegxt And Jpeg Algorithms Through The Anatomical Regions Of Interest, Zhongqiang Li, Alexandra Ramos, Zheng Li, Michelle L. Osborn, Waleed Zaid, Xin Li, Yanping Li, Jian Xu

Faculty Publications

Currently, plenty of image data is generated that complicate storage and image transmission. Great efforts have been attempted on how to increase compression ratio (CR) without loss of critical diagnostic information. In this study, we designed two optimized JPEGXT (JPEGXT_OPT) and JPEG (JPEG_OPT) approaches by amplifying discrete cosine transform coefficients and using the entire anatomical region as ROI (region of interest). We found that ROI percentages have a great impact CR: smaller ROI percentages (10–30 %) could obtain a larger CR. Under the near-lossless compression, JPEGXT_OPT could have CRs up to 4.0 under small ROI percentages (10–30 %), while only …

The State Of Architectural Labor, Ivy Mcclure

Honors Capstones

No abstract provided.

Improvement Of Existing Stage-Top Incubator For Cell Imaging (Stici), Alyson Goree

Honors Capstones

No abstract provided.

On The Application Of Probabilistic Decline Curve Analysis To Unconventional Reservoirs, U. C. Egbe, O. O. Awoleke, O. M. Olorode, S. D. Goddard

Faculty Publications

Several authors have worked on combining decline curve analysis (DCA) models and stochastic algorithms for probabilistic DCAs. However, there are no publications on the application of these probabilistic decline curve models to all the major shale basins in the United States. Also, several empirical and analytical decline curve models have been developed to fit historical production data better; there is no systematic investigation of the relevance of the efforts on new model development compared with the efforts to quantify the uncertainty associated with the “noise” in the historical data. This work compares the uncertainty associated with determining the best-fit model …

Regenerative Medicine For Tendon/Ligament Injuries: De Novo Equine Tendon/Ligament Neotissue Generation And Application, Takashi Taguchi

LSU Doctoral Dissertations

Tendon and ligament injuries are debilitating conditions across species. Poor regenerative capacities of these tissues limit restoration of original functions. The first study evaluated the effect of cellular administration on tendon/ligament injuries in horses using meta-analysis. The cellular administration was effective in restoring ultrasonographic echogenicity and increasing vascularity during early phase of healing. Additionally, it improved microstructural organization of healed tissue in terms of cellularity and fiber alignment. However, the study did not support its use for increasing rate of return to performance, expression/deposition of tendon-specific genes/proteins, or mechanical properties.

The findings led to the second study that engineered implantable …

Synergistic Role Of Temperature And Salinity In Aggregation Of Nonionic Surfactant-Coated Silica Nanoparticles, Yingzhen Ma, Christian Heil, Gergely Nagy, William T. Heller, Yaxin An, Arthi Jayaraman, Bhuvnesh Bharti

Faculty Publications

The adsorption of nonionic surfactants onto hydrophilic nanoparticles (NPs) is anticipated to increase their stability in aqueous medium. While nonionic surfactants show salinity- and temperature-dependent bulk phase behavior in water, the effects of these two solvent parameters on surfactant adsorption and self-assembly onto NPs are poorly understood. In this study, we combine adsorption isotherms, dispersion transmittance, and small-angle neutron scattering (SANS) to investigate the effects of salinity and temperature on the adsorption of pentaethylene glycol monododecyl ether (C12E5) surfactant on silica NPs. We find an increase in the amount of surfactant adsorbed onto the NPs with increasing temperature and salinity. …

Coded Ceramics: Computational Design Of Persian Ceramics, Nasrin Iravani

LSU Doctoral Dissertations

This research explores the use of computer-aided technology and robotics in the creation of digital art and crafts, while also considering the cultural history of digital design. It begins with an examination of the most recognizable styles of Persian ewers made between the years 1,000 and 1,400 AD in the Islamic era. After analyzing a hundred ewers from this period, I classified them based on distinctive features such as openings, necks, bodies, spouts, handles, and bases. Then I designed a series of 3D printed ceramic vessels – titled Coded Ceramics – that were inspired by elements of the historic ewers. …

Integrating Germplasm Repositories Into Oyster Aquaculture Systems At The Pathway, Center, And Network Levels, Sarah R. Bodenstein

LSU Doctoral Dissertations

Germplasm repositories offer many potential benefits to commercial farm operations, including preserving genetic resources and increasing production capabilities. Aquaculture industries have yet to take advantage of repository storage despite decades of research evaluating cryopreservation protocols. Eastern oysters (Crassostrea virginica), for example, are a useful research species when addressing this problem. Oysters are an economically important aquaculture species and a high-throughput cryopreservation method for oysters already exists. To address the gap between protocol research and commercial application a different approach is necessary that can analyze the requirements of repository development at multiple organizational levels. The goal of this dissertation was to …

Shape Memory Polymer-Based Multifunctional Syntactic Foams, Siavash Sarrafan

LSU Doctoral Dissertations

With the increase in popularity of shape memory polymers (SMPs), especially in applications such as aerospace, textile, biomedical engineering, and even structures, the weight of the material and the devices made with it has always been a crucial factor. Using the shape memory polymer as a matrix to make a syntactic foam is one of the best and most affordable approaches to creating a lighter material that still has the shape memory effect. The addition of particles of different stiffness, strength, and size, with variable fractions, creates a composite that enables engineering the mechanical, as well as other physical and …

Functional Domains Of The Hsv-1 Ul37 Protein In Virus Infectivity And Retrograde Transport In Neurons, Carolyn Clark

LSU Doctoral Dissertations

Herpes simplex virus type 1 is large alphaherpesvirus with 20 envelope proteins and 23 tegument proteins. Virus entry is via fusion of the viral envelope with cellular membranes mediated by a complex of viral glycoproteins. Glycoprotein B (gB) is the only fusogenic glycoprotein, while other viral glycoproteins and membrane proteins including gD, gH, gL, gK and UL20 membrane protein modulate gB’s fusogenicity. Previously, Our laboratory developed the HSV-1 (VC2) vaccines strain with partial deletions in the amino termini of gK (ΔgK(31–68)) and the UL20 membrane protein (ΔUL20(4–22)). VC2 enters epithelial cells only via endocytosis followed by release of the capsid …

Kinetic And Chemical Effects Of Clays And Other Fillers In The Preparation Of Epoxy-Vinyl Ether Composites Using Radical-Induced Cationic Frontal Polymerization, Brecklyn R. Groce, Emma E. Lane, Daniel P. Gary, Douglas T. Ngo, Dylan T. Ngo, Fahima Shaon, Jorge A. Belgodere, John A. Pojman

Faculty Publications

Addition of fillers to formulations can generate composites with improved mechanical properties and lower the overall cost through a reduction of chemicals needed. In this study, fillers were added to resin systems consisting of epoxies and vinyl ethers that frontally polymerized through a radical-induced cationic frontal polymerization (RICFP) mechanism. Different clays, along with inert fumed silica, were added to increase the viscosity and reduce the convection, results of which did not follow many trends present in free-radical frontal polymerization. The clays were found to reduce the front velocity of RICFP systems overall compared to systems with only fumed silica. It …

Injectable Antioxidant And Oxygen-Releasing Lignin Composites To Promote Wound Healing, Swathi Balaji, Walker D. Short, Benjamin W. Padon, Jorge A. Belgodere, Sarah E. Jimenez, Naresh T. Deoli, Anna C. Guidry, Justin C. Green, Tanuj J. Prajapati, Fayiz Farouk, Aditya Kaul, Dongwan Son, Olivia S. Jung, Carlos E. Astete, Myungwoong Kim, Jangwook P. Jung

Faculty Publications

The application of engineered biomaterials for wound healing has been pursued since the beginning of tissue engineering. Here, we attempt to apply functionalized lignin to confer antioxidation to the extracellular microenvironments of wounds and to deliver oxygen from the dissociation of calcium peroxide for enhanced vascularization and healing responses without eliciting inflammatory responses. Elemental analysis showed 17 times higher quantity of calcium in the oxygen-releasing nanoparticles. Lignin composites including the oxygen-generating nanoparticles released around 700 ppm oxygen per day at least for 7 days. By modulating the concentration of the methacrylated gelatin, we were able to maintain the injectability of …

The Characterization Of Selected Α- And Β-Carbonic Anhydrases Of Arabidopsis Thaliana, Hiruni Weerasooriya

LSU Doctoral Dissertations

Carbonic anhydrases (CAs) are zinc-metalloenzymes that interconvert two inorganic carbon (Ci) species, CO₂ and HCO₃^-. In Arabidopsis thaliana, there are eight αCA genes, six βCA genes, three γCA genes, and two γCA-like genes. The majority of CA research in plants has focused on finding a link between CA activity and photosynthesis rates. Since the CA genes are expressed in different plant tissues and multiple CA isoforms are distributed among various organelles of the plant cell, I hypothesize that CAs facilitate CO₂ diffusion among cell compartments and maintain Ci pools for carbon-requiring reactions by interconverting …

Inverse Machine Learning Discovered Metamaterials With Record High Recovery Stress, Adithya Challapalli, John Konlan, Guoqiang Li

Faculty Publications

Lightweight shape memory polymer (SMP) metamaterials integrated with high strength, high flexibility, and high recovery stress are highly desired in load carrying structures and devices. A grand challenge is that these desired properties have contradictory requirements, for instance between strength and flexibility, and between flexibility and recovery stress. In this study, an inverse design framework using statistical tools and machine learning models is developed to design thin-walled cellular structures with the desired properties. The discovered thin-walled cellular structures are 3D printed using a novel SMP, which exhibited excellent structural properties with record high specific recovery stress. For comparison purpose, lattice …

Optimization Of Host Cell-Compatible, Antimicrobial Peptides Effective Against Biofilms And Clinical Isolates Of Drug-Resistant Bacteria, Jenisha Ghimire, Robert J. Hart, Anabel Soldano, Charles H. Chen, Shantanu Guha, Joseph P. Hoffmann, Kalen M. Hall, Leisheng Sun, Benjamin J. Nelson, Timothy K. Lu, Jay K. Kolls, Mario Rivera, Lisa A. Morici, William C. Wimley

Faculty Publications

Here, we describe the continued synthetic molecular evolution of a lineage of host-compatible antimicrobial peptides (AMP) intended for the treatment of wounds infected with drug-resistant, biofilm-forming bacteria. The peptides tested are variants of an evolved AMP called d-amino acid CONsensus with Glycine Absent (d-CONGA), which has excellent antimicrobial activities in vitro and in vivo. In this newest generation of rational d-CONGA variants, we tested multiple sequence-structure-function hypotheses that had not been tested in previous generations. Many of the peptide variants have lower antibacterial activity against Gram-positive or Gram-negative pathogens, especially variants that have altered hydrophobicity, secondary structure potential, or spatial …

Image Analysis Methodology For Evaluating Coating Uniformity Of Drug-Coated Angioplasty Balloons, Allison Dobson Zieschang

LSU Master's Theses

Percutaneous transluminal balloon angioplasty (PTA) is a surgical procedure to treat peripheral artery disease, but restenosis causes suboptimal outcomes in many patients. Drug-coated angioplasty balloons (DCBs) were developed to reduce the risk of restenosis by delivering anti-proliferative drugs to the lesion. The efficacy of DCBs depends on factors like drug loading and drug release rate, both of which are directly impacted by the coating uniformity. This thesis evaluates the uniformity of DBCs using fluorescence microscopy, scanning electron microscopy (SEM), qualitative analysis, and an image processing algorithm. Uniformity was quantified by three measurements: histogram standard deviation, histogram percentage of coverage, and …

Removal Of Radionuclides Using Capacitive Deionization, Yusik Won

LSU Doctoral Dissertations

Severe nuclear accidents, including the Fukushima nuclear power plant accident, can lead to the discharge of large amounts of radionuclides into aquatic environments. Some radionuclides such as ¹³⁷Cs and ⁹⁰Sr have long half-lives and can remain in the environment for a long period of time. These radionuclides can be detrimental to humans and the environments because they can cause human and environmental exposure to ionizing radiation and because they can be bioaccumulated and biomagnified. Therefore, in case of a severe accident and a radioactive spill, it is important to quickly clean up and treat radioactively contaminated water to …

Ion Selective And Water Resistant Cellulose Nanofiber/Mxene Membrane Enabled Cycling Zn Anode At High Currents, Wangwang Xu, Xiaobin Liao, Weina Xu, Kangning Zhao, Guang Yao, Qinglin Wu

Faculty Publications

Aqueous rechargeable zinc ion batteries (ZIBs) are regarded as a promising candidates for next-generation energy storage devices but strongly hindered by the limited utilization of the zinc metal anode (below 5%) due to the active water/anion corrosion. Herein, an ion selective and water-resistant cellulose nanofiber (CNF)/MXene composite membrane has been developed through molecular sieving to restrict active water and anions from the electrode/electrolyte interface through dehydration of zinc ions, avoiding the water/anion-induced corrosion/decomposition. In this way, the CNF/MXene@Zn anode exhibits significantly enhanced coulombic efficiency (99.5 % at 10 mA cm-2) and low voltage hysteresis. Moreover, coated with CNF/MXene composite membrane, …

Calibration And Use Of S3f Sensor For Normal And Shear Stress Measurements In Soil, Hussein Alqrinawi

LSU Master's Theses

Innovative sensors can provide new capabilities to monitor and understand the behavior of soil, rock, and geo-structures and help geotechnical engineers make informed decisions about the construction and maintenance of geo-structures. This study introduced, calibrated, and validated one such sensor, the Surface Stress Sensitive Film (S3F) point sensor, for both normal and shear stress measurements in soil along the soil-structure interface. The measurements of S3F sensor rely on the deformation of an elastic film that is monitored by a floating element embedded in the elastic film. This sensor provides measurements of the 3D deformation of the film which are converted …

Seasonal Seepage Fluid Flow And Pressure Detection Beneath Flood Protection Levees In The Lower Mississippi River Valley Using Non-Invasive Geophysical Methods, Daniel Locci

LSU Doctoral Dissertations

This study explores the use of shear-wave seismic reflection and electrical resistivity techniques to complement our understanding of seepage pore pressure variations and soil type estimation beneath earthen levees in the Mississippi River floodplain. The seasonal variations of water level in the river create changes in pore pressure in the adjacent aquifer, which can be detected using time-lapse shear-wave velocity analysis. The seismic reflection patterns during these pressure variations show changes in velocity that can be translated into changes in effective pressure, allowing us to distinguish between confined and leaky aquifers.

In addition, the integration of geophysical methods such as …

Development Of Novel Electrodes And Electrolytes For Safer Aqueous Ammonium Ion Batteries With Enhanced Performance., Shelton Farai Kuchena

LSU Doctoral Dissertations

The Lithium-ion battery (LIBs) system has dominated the battery market because of its superior energy and power density. Problems related to LIBs such as safety, scarcity of cobalt and lithium have led researchers to explore alternative battery systems. NH₄⁺ ion is a nonmetal charge carrier with lower molar mass (18 mol g^-1) and smaller hydrated ionic size (3.31 Å) which results in excellent electrochemical properties. Furthermore, NH₄⁺ ion has a tetrahedral structure that has no preferred orientation as compared to spherical metal ions giving a different intercalation chemistry based on hydrogen bonding. These properties …

Rapid Intensification As A Crucial Hurricane Hazard: Educating And Empowering Young Stakeholders Affected By Hurricanes On The Gulf Coast, Kathleen M. Benedetto

LSU Doctoral Dissertations

In recent decades, the scientific ability to project tropical cyclone (TC) intensities and tracks has improved. Hurricanes undergoing the process of rapid intensification (RI) have created new barriers in formulating predictions of TC paths and peak velocities. Current research suggests the warming climate may produce more intense TCs with a higher probability of undergoing RI during their life cycle. The increased likelihood of rapidly intensifying TCs necessitates the development of an RI climatology spanning the current North Atlantic record. A time series count analysis suggests a significant increasing trend of RI events in the Atlantic basin by 29.1% (17%–45%) from …

Examining The Impact Of Different Street Lighting Schemes On Traffic Safety And Drivers’ Behaviors At Unsignalized Intersections, Hisham Mohamed Abdu Kunnah

LSU Master's Theses

Lack of visibility is one of the main challenges that significantly impact drivers’ ability to safely perform driving tasks at night especially at unsignalized intersections. Several prior studies indicated that lighting enhances nighttime traffic safety. Nevertheless, lighting is not mandatory at unsignalized intersections in many states including Louisiana. This study aimed to investigate if lack of lighting is a contributing factor that affects traffic safety at unsignalized intersections in Louisiana. In addition, this study strived to identify current lighting policies adopted by other states, examine if there are any low-cost countermeasures implemented by other states to improve nighttime visibility, and …

The Hillman Site (16ebr60): A Glimpse Into Pre-Contact South Louisiana, Brandy Kerr

LSU Master's Theses

Situated along the north bank of Bayou Manchac lies the pre- and post-contact Hillman site, 16EBR60. First discovered in 1960 by the landowner, George Menefee, the site was subsequently investigated by Louisiana State University archaeologist Dr. William Haag, who pronounced the site a Marksville village, due to the large number of lithic tools recovered from the site. Subsequent investigations at the site by Surveys Unlimited Research Associates, Inc. (SURA) in 2021 confirmed the Marksville component of the site and found occupation continued into the succeeding Troyville and Coles Creek cultures. The principal research questions asked include: (1) How does the …

20-Year Assessment Of Total Suspended Sediment (Tss) Variability In Barataria Bay From Modis Ocean Color Using A Combination Of Adaptive Semi-Analytical And Neural Network Algorithms, Bijaylaxmi Sahoo

LSU Master's Theses

Barataria Bay, a hydrologically dynamic basin in the northern Gulf of Mexico, exhibits a distinct spatio-temporal distribution of total suspended sediment (TSS). However, studies on sediment distribution are limited by availability of in-situ data as well as the limitation of ocean color algorithms for suspended sediments in shallow optically complex waters. Barataria Bay TSS concentration profile is complex, influenced in the upper basin by fresh water sources such as the Davis Pond Freshwater Diversion, and in the lower bay by the river plume and marine influence near the mouth of the bay. To efficiently study the sediment dynamics in the …

Numerical Flume For Wave Dissipation By Mangrove Prop Roots, Rebecca L. Schurr

LSU Master's Theses

Mangroves provide shorelines with many beneficial engineering services, including shoreline stabilization, wave attenuation, and damage mitigation during tsunami or tropical cyclone events. This research focuses on wave attenuation rates and drag coefficients, and how they are affected by mangrove prop roots. Previous lab research using a physical wave flume has quantified wave height decay and drag coefficients for synthetic mangrove forests and confirmed that attenuation does indeed increase as mangrove forest density increases. This research will use a 3D numerical flume model developed in Proteus, a Python package, to simulate prior physical model experiments. This work will attempt to validate …

Essays On The Economics Of Health And Education, Thao Bui

LSU Doctoral Dissertations

This dissertation consists of three chapters on the economics of health and education. In Chapter 2, I examine the effect of prenatal exposure to Agent Orange, a dioxin- contaminated herbicide that was dispersed on a large scale in South Vietnam for military operations during the Vietnam War, on educational attainment of Vietnamese civilians. The identification strategy exploits province-by-cohort variation in the intensity of Agent Orange sprayed. I find that controlling for conventional bombing, cohorts exposed in utero to Agent Orange (who were born between 1962 and 1971) have lower educational attainment compared to other birth cohorts. The same inference is …

Characterizing Marr Homologs That Mediate Bacterial Fitness And Survival, George Chukwuemeka Nwokocha

LSU Doctoral Dissertations

Plant disease outbreaks are on the rise, threatening food security in many parts of the globe. To address these enormous challenges, new intervention strategies like bio-controls are being used as an important sustainable alternative to mitigate the negative effects of pathogens and increase the quality and productivity of agricultural crops. MarR family transcriptional regulators have been studied for their involvement in regulating bacterial virulence genes that help colonize plant hosts and therefore could serve as targets for biocontrol. The transcriptional regulator PecS, a member of the MarR family, is encoded by select bacterial pathogens and we show here that PecS …

Domain Specific Analysis Of Privacy Practices And Concerns In The Mobile Application Market, Fahimeh Ebrahimi Meymand

LSU Doctoral Dissertations

Mobile applications (apps) constantly demand access to sensitive user information in exchange for more personalized services. These-mostly unjustified-data collection tactics have raised major privacy concerns among mobile app users. Existing research on mobile app privacy aims to identify these concerns, expose apps with malicious data collection practices, assess the quality of apps' privacy policies, and propose automated solutions for privacy leak detection and prevention. However, existing solutions are generic, frequently missing the contextual characteristics of different application domains. To address these limitations, in this dissertation, we study privacy in the app store at a domain level. Our objective is to …

Effects Of Task-Switching On Proactive Control And Metamemory Regulation, Jessica Hacker

LSU Doctoral Dissertations

Past researchers have proposed a relationship between cognitive control and metamemory and several studies have provided the most support for a relationship between task-switching and metamemory regulation. Nevertheless, the evidence has been correlational. To my knowledge, the present study was the first to include an experimental manipulation incorporating a dual-task that required task-switching within a feeling of knowing (FOK) paradigm to directly observe the effects of task-switching on FOK accuracy. Research on cognitive control has demonstrated that engaging in proactive cognitive control typically leads to better performance in cognitive tasks and that young adults are naturally biased to engage in …