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“The Lord Is The Maker Of Them All” Black Membership In White Baptist Churches In Antebellum Louisiana, Alison Foster Apr 2022

“The Lord Is The Maker Of Them All” Black Membership In White Baptist Churches In Antebellum Louisiana, Alison Foster

Honors Capstones

No abstract provided.


Trump’S Trade War: An Economic And Diplomatic Analysis From A Louisianan’S Perspective, Logan P. Berthelot Apr 2022

Trump’S Trade War: An Economic And Diplomatic Analysis From A Louisianan’S Perspective, Logan P. Berthelot

Honors Capstones

No abstract provided.


Louisiana Social Studies: A Look Into The Culture, History And Business Of Our State, Ava Borksey Apr 2022

Louisiana Social Studies: A Look Into The Culture, History And Business Of Our State, Ava Borksey

Honors Capstones

No abstract provided.


Spring 2022 Catalog, Lsu Press Apr 2022

Spring 2022 Catalog, Lsu Press

LSU Press Seasonal Catalogs

No abstract provided.


Resistance Allele Frequency To Cry1ab And Vip3aa20 In Helicoverpa Zea (Boddie) (Lepidoptera: Noctuidae) In Louisiana And Three Other Southeastern U.S. States, Shucong Lin, Isaac Oyediran, Ying Niu, Sebe Brown, Don Cook, Xinzhi Ni, Yan Zhang, Francis P.F. Reay-Jones, Jeng Shong Chen, Zhimou Wen, Marcelo Dimase, Fangneng Huang Apr 2022

Resistance Allele Frequency To Cry1ab And Vip3aa20 In Helicoverpa Zea (Boddie) (Lepidoptera: Noctuidae) In Louisiana And Three Other Southeastern U.S. States, Shucong Lin, Isaac Oyediran, Ying Niu, Sebe Brown, Don Cook, Xinzhi Ni, Yan Zhang, Francis P.F. Reay-Jones, Jeng Shong Chen, Zhimou Wen, Marcelo Dimase, Fangneng Huang

Faculty Publications

The corn earworm/bollworm, Helicoverpa zea (Boddie), is a pest species that is targeted by both Bacillus thuringiensis (Bt) maize and cotton in the United States. Cry1Ab and Vip3Aa20 are two common Bt toxins that are expressed in transgenic maize. The objective of this study was to determine the resistance allele frequency (RAF) to Cry1Ab and Vip3Aa20 in H. zea populations that were collected during 2018 and 2019 from four southeastern U.S. states: Louisiana, Mississippi, Georgia, and South Carolina. By using a group-mating approach, 104 F2 iso-lines of H. zea were established from field collections with most iso-lines (85) from Louisiana. …


Court Legitimacy & The Shadow Docket, Colton J. Tilley Apr 2022

Court Legitimacy & The Shadow Docket, Colton J. Tilley

Honors Capstones

No abstract provided.


Influence Of Climate Change On Immigration Rates In Honduras Internally And Internationally, Revathi Menon Apr 2022

Influence Of Climate Change On Immigration Rates In Honduras Internally And Internationally, Revathi Menon

Honors Capstones

No abstract provided.


Changes In Girls’ Educational Opportunities In Former Afrique Occidentale Française (Aof) States Since Independence (1960), Claire Inderkummen Apr 2022

Changes In Girls’ Educational Opportunities In Former Afrique Occidentale Française (Aof) States Since Independence (1960), Claire Inderkummen

Honors Capstones

No abstract provided.


Wetlands In China: Evolution, Carbon Sequestrations And Services, Threats, And Preservation/Restoration, Siyuan Ye, Lixin Pei, Lei He, Liujuan Xie, Guangming Zhao, Hongming Yuan, Xigui Ding, Shaofeng Pei, Shixiong Yang, Xue Li, Edward Laws Apr 2022

Wetlands In China: Evolution, Carbon Sequestrations And Services, Threats, And Preservation/Restoration, Siyuan Ye, Lixin Pei, Lei He, Liujuan Xie, Guangming Zhao, Hongming Yuan, Xigui Ding, Shaofeng Pei, Shixiong Yang, Xue Li, Edward Laws

Faculty Publications

No abstract provided.


Wetlands In China: Evolution, Carbon Sequestrations And Services, Threats, And Preservation/Restoration, Siyuan Ye, Lixin Pei, Lei He, Liujuan Xie, Guangming Zhao, Hongming Yuan, Xigui Ding, Shaofeng Pei, Shixiong Yang, Xue Li, Edward Laws Apr 2022

Wetlands In China: Evolution, Carbon Sequestrations And Services, Threats, And Preservation/Restoration, Siyuan Ye, Lixin Pei, Lei He, Liujuan Xie, Guangming Zhao, Hongming Yuan, Xigui Ding, Shaofeng Pei, Shixiong Yang, Xue Li, Edward Laws

Faculty Publications

No abstract provided.


Beyond Appetite Regulation: Targeting Energy Expenditure, Fat Oxidation, And Lean Mass Preservation For Sustainable Weight Loss, Berit Østergaard Christoffersen, Guillermo Sanchez-Delgado, Linu Mary John, Donna H. Ryan, Kirsten Raun, Eric Ravussin Apr 2022

Beyond Appetite Regulation: Targeting Energy Expenditure, Fat Oxidation, And Lean Mass Preservation For Sustainable Weight Loss, Berit Østergaard Christoffersen, Guillermo Sanchez-Delgado, Linu Mary John, Donna H. Ryan, Kirsten Raun, Eric Ravussin

Clinical Research Faculty Publications

New appetite-regulating antiobesity treatments such as semaglutide and agents under investigation such as tirzepatide show promise in achieving weight loss of 15% or more. Energy expenditure, fat oxidation, and lean mass preservation are important determinants of weight loss and weight-loss maintenance beyond appetite regulation. This review discusses prior failures in clinical development of weight-loss drugs targeting energy expenditure and explores novel strategies for targeting energy expenditure: mitochondrial proton leak, uncoupling, dynamics, and biogenesis; futile calcium and substrate cycling; leptin for weight maintenance; increased sympathetic nervous system activity; and browning of white fat. Relevant targets for preserving lean mass are also …


Sympathomimetic Increases Resting Energy Expenditure Following Bariatric Surgery: A Randomized Controlled Clinical Trial, Candida J. Rebello, Frank L. Greenway, Dachuan Zhang, William D. Johnson, Emma Patterson, William Raum Apr 2022

Sympathomimetic Increases Resting Energy Expenditure Following Bariatric Surgery: A Randomized Controlled Clinical Trial, Candida J. Rebello, Frank L. Greenway, Dachuan Zhang, William D. Johnson, Emma Patterson, William Raum

Clinical Research Faculty Publications

Objective: The aim of this study was to test the hypothesis that ephedrine + caffeine (EC) reduces the fall in resting energy expenditure (REE) following bariatric surgery. Methods: This 32-week, randomized, double-blinded, placebo-controlled trial included 142 patients who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) surgery. Participants were randomized to either EC or placebo for 27 weeks, beginning 5 weeks post surgery. The primary end points were change in REE (measured), percentage of predicted REE ([measured REE/Harris-Benedict equation-predicted REE] × 100), and body composition. Secondary outcomes included change in percentage of weight. Adverse events (AEs) were recorded. Results: …


Exercise As A Moderator Of Persistent Neuroendocrine Symptoms Of Covid-19, Candida J. Rebello, Christopher L. Axelrod, Charles F. Reynolds, Frank L. Greenway, John P. Kirwan Apr 2022

Exercise As A Moderator Of Persistent Neuroendocrine Symptoms Of Covid-19, Candida J. Rebello, Christopher L. Axelrod, Charles F. Reynolds, Frank L. Greenway, John P. Kirwan

Division of Basic Science Faculty Publications

Precipitated by chronic psychological stress, immune system dysregulation, and a hyperinflammatory state, the sequelae of postacute COVID-19 (long COVID) include depression and new-onset diabetes. We hypothesize that exercise counters the neuropsychiatric and endocrine sequelae of long COVID by inducing the release of circulating factors that mediate the anti-inflammatory response, support brain homeostasis, and increase insulin sensitivity.


Online Bayesian Optimization For A Recoil Mass Separator, S. A. Miskovich, F. Montes, G. P.A. Berg, J. Blackmon, K. A. Chipps, M. Couder, C. M. Deibel, K. Hermansen, A. A. Hood, R. Jain, T. Ruland, H. Schatz, M. S. Smith, P. Tsintari, L. Wagner Apr 2022

Online Bayesian Optimization For A Recoil Mass Separator, S. A. Miskovich, F. Montes, G. P.A. Berg, J. Blackmon, K. A. Chipps, M. Couder, C. M. Deibel, K. Hermansen, A. A. Hood, R. Jain, T. Ruland, H. Schatz, M. S. Smith, P. Tsintari, L. Wagner

Faculty Publications

The Separator for Capture Reactions (SECAR) is a next-generation recoil separator system at the Facility for Rare Isotope Beams (FRIB) designed for the direct measurement of capture reactions on unstable nuclei in inverse kinematics. To maximize the performance of this system, stringent requirements on the beam alignment to the central beam axis and on the ion-optical settings need to be achieved. These can be difficult to attain through manual tuning by human operators without potentially leaving the system in a suboptimal and irreproducible state. In this work, we present the first development of online Bayesian optimization with a Gaussian process …


Sgk1 Is Essential For Meiotic Resumption In Mammalian Oocytes, Edgar Del Llano, Rajan Iyyappan, Daria Aleshkina, Tomas Masek, Michal Dvoran, Zongliang Jiang, Martin Pospisek, Michal Kubelka, Andrej Susor Apr 2022

Sgk1 Is Essential For Meiotic Resumption In Mammalian Oocytes, Edgar Del Llano, Rajan Iyyappan, Daria Aleshkina, Tomas Masek, Michal Dvoran, Zongliang Jiang, Martin Pospisek, Michal Kubelka, Andrej Susor

Faculty Publications

In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic division and become mature (ready for fertilization). At a molecular level, the master regulator of prophase I arrest and meiotic resumption is the maturation-promoting factor (MPF) complex, formed by the active form of cyclin dependent kinase 1 (CDK1) and Cyclin B1. However, we still do not have complete information regarding the factors implicated in MPF activation. In this study we …


Strain Energy-Based Fatigue Failure Analyses Of Lb-Pbf Inconel 718: Effect Of Build Orientation, Arash P. Jirandehi, Behnam Hajshirmohammadi, Patricio Carrion, M. M. Khonsari, Nima Shamsaei, Shuai Shao Apr 2022

Strain Energy-Based Fatigue Failure Analyses Of Lb-Pbf Inconel 718: Effect Of Build Orientation, Arash P. Jirandehi, Behnam Hajshirmohammadi, Patricio Carrion, M. M. Khonsari, Nima Shamsaei, Shuai Shao

Faculty Publications

Additively manufactured Inconel 718 parts fabricated in three build orientations (horizontal, vertical, and angled at 45 degrees) are tested in fully-reversed bending fatigue mode. Damping measurements via the Impulse Excitation technique are used to assess the defects content in the microstructure and fractography analysis is performed to detect the root cause of failure. Two micro- and macro-scale methodologies of fatigue damage estimation based on the dissipated heat per cycle and the statistical estimation of micro-plastic strain energies are used to assess fatigue damage. It is shown that at a given stress level, the vertically built specimens endure the most fatigue …


Are Long-Period Exoplants Around Cool Stars More Common Than We Thought?, Emily Jane Safron Mar 2022

Are Long-Period Exoplants Around Cool Stars More Common Than We Thought?, Emily Jane Safron

LSU Doctoral Dissertations

The Kepler mission has been the catalyst for discovery of nearly 5,000 confirmed and candidate exoplanets. The majority of these candidates orbit Sun-like stars, and have orbital periods comparable to or shorter than that of the Earth, due to the selection bias inherent in the transit method and the limitations of automated transit search algorithms. We aim to develop a richer understanding of the population of exoplanets around the lowest-mass stars, the M spectral type. We are particularly interested in exoplanets with long orbital periods, which are difficult or impossible to find using standard transit search algorithms. In our study, …


Pharmakon In The Firelands: Connecting Historical Discourses And Small-Town Social Contexts With Substance Use Experience, Andrew Robert Burns Mar 2022

Pharmakon In The Firelands: Connecting Historical Discourses And Small-Town Social Contexts With Substance Use Experience, Andrew Robert Burns

LSU Doctoral Dissertations

The ongoing increase in opioid and polysubstance-related overdoses and mortality in United States coincides with a shift in the ways substance use is understood. Once almost exclusively treated as a criminal problem, substance use, and overdose is increasingly viewed in terms of public health and from an urban to rural issue. The discourse surrounding the use of psychoactive substances largely omits the voices of the very people who use them. Likewise, the social context of small towns, at once not quite rural nor entirely urban, is generally given little consideration. To address these gaps in the research, I conduct two …


Novel Roles For Viral Gpcrs In Cmv Latency And Immunity, Timothy White Mar 2022

Novel Roles For Viral Gpcrs In Cmv Latency And Immunity, Timothy White

LSU Doctoral Dissertations

Human cytomegalovirus (HCMV) is a widespread, highly prevalent pathogen with severe consequences in vulnerable populations. HCMV and the related murine cytomegalovirus (MCMV) encode multiple G protein-coupled receptor (GPCR) homologs which are involved in latency, immune evasion, and tissue tropism and dissemination. In this work, we investigate the mechanisms of two CMV-encoded GPCR homologs, HCMV US28 and MCMV M33, in latency and T cell immune evasion. Chapter 2 describes the isolation and immortalization of a salivary gland-derived mesenchymal cell line, termed mSGM. These cells are permissive to MCMV infection and express all three BALB/c mouse MHC class I isotypes, making them …


The Design, Construction, And Testing Of A Recombinant Dna Vaccine For Brucella Abortus And Brucella Melitensis, Stephanie Lynn Korle Mar 2022

The Design, Construction, And Testing Of A Recombinant Dna Vaccine For Brucella Abortus And Brucella Melitensis, Stephanie Lynn Korle

LSU Doctoral Dissertations

Brucella spp. are a bacterium that cause brucellosis, a zoonotic disease, which is commonly seen in cattle, sheep, goats, swine, and canines. Brucellosis is a problem worldwide, although it is eradicated in some countries (Garin-Bastuji et al. 1998). The reason for designing recombinant DNA (rDNA) vaccines opposed to utilizing the live-attenuated vaccines on the market is that they cannot be given to pregnant animals without potentially causing abortion, while an rDNA vaccine should be safe for pregnant animals since it does not contain viable bacteria. Also, there are no serological tests that can accurately distinguish between an animal vaccinated …


Tutorial: Thermomechanical Constitutive Modeling Of Shape Memory Polymers, Cheng Yan, Guoqiang Li Mar 2022

Tutorial: Thermomechanical Constitutive Modeling Of Shape Memory Polymers, Cheng Yan, Guoqiang Li

Faculty Publications

Shape memory polymers (SMPs) are one of the intriguing functional materials and have been widely and intensively studied. In order to apply these new polymers to load bearing engineering structures and devices, developing physics-based thermomechanical constitutive models is mandatory. The aim of this Tutorial is to demonstrate how to establish a thermomechanical constitutive model for SMPs. It begins with classifications of SMPs, followed by a discussion on the underlying physics for different SMPs. After that, three classical SMP thermomechanical modeling frameworks are introduced, which include the visco-elasto-plastic based rheological framework, the storage strain-based phase transition framework, and the representative unit …


Weed Management With Pro-Herbicides Benzobicylon And Florpyrauxifen-Benzyl In Louisiana Rice Production, William Bradley Greer Mar 2022

Weed Management With Pro-Herbicides Benzobicylon And Florpyrauxifen-Benzyl In Louisiana Rice Production, William Bradley Greer

LSU Doctoral Dissertations

Field studies were conducted in 2020 and 2021 to evaluate benzobicyclon tolerance to 71 weedy rice accessions collected from Louisiana and southern Arkansas. Benzobicyclon was applied at 373 g ai ha-1 as a postflood application on 3- to 4-leaf rice. At 28 DAT, less than 15% control was observed on 70% of the accessions and 80% or better control was observed on 3% of accessions. Inconsistent weedy rice control can be attributed to the presence or absence of a functional HIS1 allele. The functional HIS1 allele was present in 96% of accessions when treated with benzobicyclon control was less …


Pemnet: A Transfer Learning-Based Modeling Approach Of High-Temperature Polymer Electrolyte Membrane Electrochemical Systems, Luis A. Briceno-Mena, José A. Romagnoli, Christopher G. Arges Mar 2022

Pemnet: A Transfer Learning-Based Modeling Approach Of High-Temperature Polymer Electrolyte Membrane Electrochemical Systems, Luis A. Briceno-Mena, José A. Romagnoli, Christopher G. Arges

Faculty Publications

Widespread adoption of high-temperature electrochemical systems such as polymer electrolyte membrane fuel cells (HT-PEMFCs) requires models and computational tools for accurate optimization and guiding new materials for enhancing fuel cell performance and durability. While robust and better suited for extrapolation, knowledge-based modeling has limitations as it is time-consuming and requires information about the system that is not always available (e.g., material properties and interfacial behavior between different materials). Data-driven modeling, on the other hand, is easier to implement but often necessitates large datasets that could be difficult to obtain. In this contribution, knowledge-based modeling and data-driven modeling are combined by …


Impact Of New Technologies On Weed Control In Louisiana Rice Production, David C. Walker Mar 2022

Impact Of New Technologies On Weed Control In Louisiana Rice Production, David C. Walker

LSU Doctoral Dissertations

Field studies were conducted in 2018-2021 at the LSU Agricultural Center’s H.R. Caffey Rice Research Station (RRS) near Crowley, LA, and the Dean Lee Research and Extension Center (DLREC) near Alexandria, LA to evaluate off-target florpyrauxifen movement on soybean. Soybean was treated with florpyrauxifen at the V4-V5 or R1-R2 growth stages. Soybean injury was evaluated at 1, 7, 14, and 28 days after treatment (DAT) and soybean plant height (cm) was recorded at 7, 14, and 28 DAT. At soybean maturity, yield and individual yield components were subjected to regression analysis to describe the relationship between florpyrauxifen rate and soybean …


Engineered Cementitious Composites, Gabriel Andres Arce, Marwa Hassan, Hassan Noorvand, Tyson Rupnow, Michele Barbato Mar 2022

Engineered Cementitious Composites, Gabriel Andres Arce, Marwa Hassan, Hassan Noorvand, Tyson Rupnow, Michele Barbato

College of Engineering Patents

Engineered Cementitious Composites (ECC) and cement products including Engineered Cementitious Composites are provided. The ECC can include cement, sugar cane bagasse ash, and fiber. The sugar cane bagasse ash can be processed to provide a partial cement or sand replacement in ECCs and cement products.


Automated Machine Learning: A Case Study Of Genomic “Image-Based” Prediction In Maize Hybrids, Giovanni Galli, Felipe Sabadin, Rafael Massahiro Yassue, Cassia Galves, Humberto Fanelli Carvalho, Jose Crossa, Osval Antonio Montesinos-López, Roberto Fritsche-Neto Mar 2022

Automated Machine Learning: A Case Study Of Genomic “Image-Based” Prediction In Maize Hybrids, Giovanni Galli, Felipe Sabadin, Rafael Massahiro Yassue, Cassia Galves, Humberto Fanelli Carvalho, Jose Crossa, Osval Antonio Montesinos-López, Roberto Fritsche-Neto

Faculty Publications

Machine learning methods such as multilayer perceptrons (MLP) and Convolutional Neural Networks (CNN) have emerged as promising methods for genomic prediction (GP). In this context, we assess the performance of MLP and CNN on regression and classification tasks in a case study with maize hybrids. The genomic information was provided to the MLP as a relationship matrix and to the CNN as “genomic images.” In the regression task, the machine learning models were compared along with GBLUP. Under the classification task, MLP and CNN were compared. In this case, the traits (plant height and grain yield) were discretized in such …


The Herpes Simplex Virus Type-1 (Hsv-1), Vc2 Live-Attenuated Vaccine Strain Induces Robust Antitumor Immune Responses And Ameliorates Intra-Tumor Immunosuppression In An Immunocompetent B16f10-Derived Murine Melanoma Model, Ifeanyi Kingsley Uche Mar 2022

The Herpes Simplex Virus Type-1 (Hsv-1), Vc2 Live-Attenuated Vaccine Strain Induces Robust Antitumor Immune Responses And Ameliorates Intra-Tumor Immunosuppression In An Immunocompetent B16f10-Derived Murine Melanoma Model, Ifeanyi Kingsley Uche

LSU Doctoral Dissertations

Current cancer immunotherapies include immune checkpoint inhibitors, adoptive cellular therapy, and cancer vaccines. While some of these therapies have met with great clinical success, they are associated with several limitations. Oncolytic virotherapy (OVT) has emerged as a bonafide promising immunotherapy, that uses viral infection to liberate tumor antigens in an immunogenic context to promote the development of anti-tumor immune responses. At present, Talimogene laherparepvec (T-VEC; Imlygic™), a modified type 1 herpes simplex virus (HSV-1) is the only FDA approved OVT for human cancer treatment (melanoma). While T-VEC is associated with limited response rates, its modest efficacy supports the continued development …


Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley Mar 2022

Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley

LSU Doctoral Dissertations

Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …


The Potential Of Dietary Bioactive Compounds Against Sars-Cov-2 And Covid-19-Induced Endothelial Dysfunction, Jack N. Losso Mar 2022

The Potential Of Dietary Bioactive Compounds Against Sars-Cov-2 And Covid-19-Induced Endothelial Dysfunction, Jack N. Losso

Faculty Publications

COVID-19 is an endothelial disease. All the major comorbidities that increase the risk for severe SARS-CoV-2 infection and severe COVID-19 including old age, obesity, diabetes, hypertension, respiratory disease, compromised immune system, coronary artery disease or heart failure are associated with dysfunctional endothelium. Genetics and environmental factors (epigenetics) are major risk factors for endothelial dysfunction. Individuals with metabolic syndrome are at increased risk for severe SARS-CoV-2 infection and poor COVID-19 outcomes and higher risk of mortality. Old age is a non-modifiable risk factor. All other risk factors are modifiable. This review also identifies dietary risk factors for endothelial dysfunction. Potential dietary …


My Favorite Murder As Discursive Performance, Taylor Dawson Feb 2022

My Favorite Murder As Discursive Performance, Taylor Dawson

LSU Doctoral Dissertations

My Favorite Murder as Discursive Performance uses performance-centered discourse analysis to explore the major narratives informing the popular true crime comedy podcast, My Favorite Murder (MFM). Hosts, Karen and Georgia draw from podcast, comedy, true crime, feminist, and mental health discourse to create a unique discursive space where “murderinos” (fans of the podcast) express and explore aspects of their own life experiences. I explore the performative strategies MFM uses and the effects of those choices, drawing on some of my own experiences as a murderino. Ultimately I argue that a performance lens reveals some of the imperfect but powerful ways …