Digital Commons Network^™

Reef Fish Demographics On Louisiana Artificial Reefs : The Effects Of Reef Size On Biomass Distribution And Foraging Dynamics, Kirsten A. Simonsen

LSU Doctoral Dissertations

Understanding the role that habitat plays in the life history of reef-associated fishes is particularly significant given the dramatic increase in the number of artificial reefs deployed in coastal ecosystems over the past 50 years. In the Gulf of Mexico, the oil and gas industry has added a significant amount of structure to the Louisiana continental shelf, creating the largest de facto artificial reef deployment area in the world. Noting their usefulness as fish habitat, the Louisiana Artificial Reef Program was established to convert decommissioned platforms into artificial reefs. However, very little quantitative information exists on how these habitats affect …

Synthetic Efforts Toward The Eastern Hemisphere Of Theonellamide C, Douglas D. Wong

LSU Doctoral Dissertations

The theonellamides (TNMs) A-F are bicyclic dodecapeptides isolated from marine sponges of the genus Theonella and were shown to display potent antifungal activity. Despite considerable synthetic effort to produce TNM F by the Shioiri group in the early 1990s, a total synthesis of a TNM has yet to be reported. This dissertation describes our efforts toward some of the required amino acid residues of TNM C and the eastern hemisphere. The production of erythro-β-hydroxyasparagine (eHyAsn) followed the synthesis of threo-β-HyAsn by Boger and co-workers, utilizing a key Sharpless aminohydroxylation reaction. The eHyAsn building block, Boc-eHyAsn(OTBS)-OH, was coupled with HCl.Phe.OMe using …

Fluorescent Materials For Chemical Sensing, Brian Gerard Imsick

LSU Doctoral Dissertations

Materials incorporating fluorescent π-electron conjugated molecular species for sensing and imaging are advantageous over other detection or identification methods such as colorimetric reporters. Fluorescent materials offer easy recognition of binding events due to the highly sensitive nature of fluorescence techniques down to the single molecule level. The properties of fluorescent molecules allow for rapid attenuation of observable readout due to the facile transport of excited state energy via both inter- and intramolecular pathways. This dissertation primarily focused on the development and study of a general platform for ratiometric fluorescent chemosensing using surface-immobilized oligomers, as well as in depth explorations of …

Oligomers Of Beta-L-Arabinosides Of Hydroxyproline : Synthesis Of The Carbohydrate Epitope Of The Art V 1 Allergen, Ning Xie

LSU Doctoral Dissertations

The pollen of mugwort is a major contributor to hay fever in Europe and North America. The chemical structure of Art v 1, the major allergen of mugwort, has been elucidated. A notable motif in Art v 1 – characterized by clusters of contiguous â-arabinosides of hydroxyproline – was found to be a key recognition element for antibodies generated in response to the natural protein. This dissertation details the chemical synthesis of oligomers of â-arabinosides of hydroxyproline and the search to establish the minimal carbohydrate epitope of Art v 1. The â-arabinoside motif, being a 1,2-cis glycoside, presents a considerable …

Thinking Together About The Common Good: The Political Implications Of Thomas Aquinas's Theory Of Conscience, Angela Concetta Miceli

LSU Doctoral Dissertations

This dissertation examines the problems confronted by claims of ‘freedom of conscience’ in contemporary political society, and argues that freedom of conscience is a critical foundational component of any free political regime. Yet, conscience is often invoked as the final authority or justification for any choice, regardless whether the action or choice violates the common good. In this case, there is a risk that conscience can become identified with subjectivism, radical individualism, or autonomy. I suggest that a re-examination of the theory of conscience found in Aquinas, especially as it relates to human reason, natural law, and prudence, contributes toward …

Soil Organic Carbon Determination For Louisiana Soils Via Portable X-Ray Fluorescence Spectroscopy, Sara Kathryn Nuss

LSU Master's Theses

As scientists work to investigate the mechanisms underlying the depletion of carbon from terrestrial ecosystems, there has been an urgent call for the development of test methods that offer reduced analysis times for soil organic carbon (SOC) determinations. Traditional laboratory techniques can be time-consuming and costly, making high-volume sample analyses problematic. Portable x-ray fluorescence spectroscopy (PXRF) provides quantitative, multi-elemental data for soil samples in as little as 60 seconds; and, unlike other spectroscopic methods, differences in elemental concentrations between field-moist and oven-dry samples are considered to be negligible when soil moisture contents are less than 20%, by weight. This study …

Evolutionary Assembly Of The Neotropical Montane Avifauna, Andres M. Cuervo

LSU Doctoral Dissertations

Three fundamental processes are thought to underlie biodiversity patterns: speciation, dispersal, and extinction. Biodiversity patterns in species-rich tropical mountains vary along horizontal (barriers), and vertical (elevation) dimensions. In this dissertation, I set out to explore the interplay between historical and ecological mechanisms hypothesized to shape diversification of Neotropical cloud forest birds. In the second chapter, I conducted comparative analyses using species-specific ecological traits, and 3,175 mtDNA sequences collected across the range of 45 co-distributed birds. First, I found that niche breadth, dispersal ability, and clade age influence lineage diversity (population differentiation). In particular, species that are old, poor dispersers, and …

Role Of Retrotransposons As A Major Source Of Intra- And Inter-Individual Epigenetic Variations In The Mammalian Genome, Muhammad Badre Ekram

LSU Doctoral Dissertations

Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements partially escape this repression mechanism. I used two approaches as my dissertation study to identify unmethylated intracisternal A-particles (IAPs) and also to understand why some of IAPs escape DNA methylation-mediated repression. Firstly, I sought to catalog the retrotransposons (LTRs and LINEs only) in the mouse genome known as ‘epialleles’ which escape the repression variably even in individuals with an identical genome sequence. Using bioinformatic approaches, 143 candidate epialleles were first identified based on their promoter activity and association with active histone modification marks. Detailed methylation analyses suggested …

Patterns And Pathways Of Wetland Sedimentation And Landscape Change In Coastal Louisiana, Andrew William Tweel

LSU Doctoral Dissertations

Coastal Louisiana wetlands exist in a dynamic physical environment and retracted dramatically in the last century. Here I examine the spatial and temporal variability of this landscape with an emphasis on the interactions between anthropogenic landscape modifications and geological processes.

The Mississippi River watershed underwent drastic changes during the past 200 years, beginning with widespread land clearing and, later, large-scale reservoir construction. These modifications caused increases in suspended sediment concentrations, then sharp decreases, and have remained relatively stable since 1960. I show how changes in land area of the Mississippi River birdfoot delta reflect these fluctuations, and that they are …

The Idiosyncratic Fantasies Of Bele Bachem : The Life And Work Of Germany's Forgotten Postwar Artist, Lydia Jane Dorsey

LSU Master's Theses

This thesis constitutes the first comprehensive analysis written in English on the life and work of German-born, post-World War II artist, Bele Bachem. By translating and critically analyzing her diverse oeuvre, which spanned both fields of "applied" and "fine" arts, this thesis examines the three stages of the artist’s career: Bachem’s "Poetic Miniatures" and theater set design under the Third Reich (1938-1945), her postwar commercial work after West Germany’s Wirtschaftswunder for Rosenthal Porcelain (1949-1966), and her mature style of narrative fantasy paintings and female portraits completed in the Schwabing bohemian district of Munich (1957-1986). With this thesis, I aim to …

Reaction Of Green Leaf Volatiles As A Source Of Secondary Organic Aerosols In Fog Droplets, Amie Kathryn Hansel

LSU Master's Theses

Green leaf volatiles (GLVs) are a group of biogenic volatile organic compounds (BVOCs) released into the atmosphere by vegetation when plants undergo stress or mechanical damage. BVOCs produce secondary organic aerosol (SOA) in the gas phase; however, their oxidation as a source of SOA in the liquid phase has not been investigated. Once released into the atmosphere, water-soluble GLVs partition into atmospheric water phases such as fog, mist, dew or rain, where they are oxidized by hydroxyl radicals (ÿOH). Photochemical oxidation yields products that are higher in molecular weight, more polar, more oxygenated, and lower in vapor pressure. When the …

Causes And Consequences Of Conflict : Exploring The Influence Of Honor-Based Norms And Values On The Experience Of Intimate Partner Violence In The United States, Michelle Elaine Pence

LSU Doctoral Dissertations

The three studies in this dissertation were posed with the common goal of revealing possible explanations for variations in the causes and consequences of interpersonal violence across regional cultures of the United States. Study 1 posed and tested two hypotheses related to the distribution of male-perpetrated intimate partner homicide across regions of the United States. The South and West, two regions characterized in full (the South) or in part (the West) by honor cultures, emerged as the regions with the highest rates of argument- and conflict- related, male-on-female intimate partner homicides in single victim/single offender incidents. Explanations provided at the …

Role Of Nod2/Rip2 Signaling In Acute Bacterial Pneumonia And Sepsis, Balamayooran Theivanthiran

LSU Doctoral Dissertations

Bacterial pneumonia and sepsis are two important causes of mortality in the world. Emergence of multidrug resistant bacteria has necessitated the development of new treatment and/or prevention strategies to augment host immune defense. In this context, the innate host defense is critical in clearing pathogenic bacteria from the host. Early neutrophil recruitment is a critical step in a multistep requence leading to bacterial clearance. Pattern recognition receptors (PRRs) play a critical role in the innate immune system. Receptor interacting protein 2 (RIP-2) is an adaptor for the nod-like receptors (NLR) NOD1 and NOD2. Nucleotide oligomerisation domain 2 (NOD2) is an …

Socially Oriented Negative Self-Referent Cognition : The Development And Validation Of A Measure, Brittany Moree Rudy

LSU Doctoral Dissertations

Social phobia, a debilitating disorder among children and adolescents, is thought to be made up of cognitive, behavioral, and physiological components. However, in children, the cognitive component of this disorder has been largely neglected by researchers. Therefore, the purpose of this study was to create and validate a new instrument, the "Socially Oriented Negative Anxious Statement (SONAS) scale,” that assesses socially oriented negative self-referent cognition in a younger population. Measurement validation procedures including, reliability, validity, and factor analysis, were utilized to examine the proposed questionnaire. Results indicated that the SONAS scale demonstrated good psychometric properties, including a sound two-factor structure …

Synthesis, Characterization And Biological Studies Of Carboranyl-Porphyrin Bioconjugates For Treatment Of Brain Tumors, Naga Venkata Satya Dinesh Kumar Bhupathiraju

LSU Doctoral Dissertations

Chapter 1 gives a brief introduction to brain tumors, approaches to deliver drug across the blood brain barrier (BBB), boron neutron capture therapy (BNCT) for brain tumors, application of carboranyl derivatives in attempt to treat brain tumors using BNCT. Chapter 2 involves synthesis, characterization and toxicity studies (In vitro and In vivo) of high boron containing pegylated cobaltabisdicarbollide porphyrin for treatment of brain tumors using BNCT. To improve the selectivity towards brain tumors we attempted conjugate several peptides to this non-toxic pegylated cobaltabiscabollide porphyrin. In vivo studies were conducted in collaboration with Dr. David G. Baker at LSU veterinary Medicine. …

Diversity And Activity Of Aerobic Thermophilic Carbon Monoxide-Oxidizing Bacteria On Kilauea Volcano, Hawaii, Caitlin Elizabeth King

LSU Doctoral Dissertations

Aerobic carbon monoxide (CO) oxidation is used by phylogenetically and physiologically diverse microorganisms inhabiting a variety of terrestrial and aquatic ecosystems. Activity assays, culture-based studies, and molecular-based approaches targeting the coxL gene, encoding the large subunit of CO dehydrogenase, were used to investigate the role of temperature in structuring CO-oxidizing communities at Kilauea Volcano, Hawai’i. CO uptake activity was assessed for unvegetated and vegetated temperate volcanic deposits that experience different temperature regimes due to plant development during ecosystem succession. Both CO-oxidizing communities had similar short-term responses to temperature; however, results from extended incubations (30 d) at elevated temperature (55 °C) …

The Rebranding Of The Brooklyn Nets : A Discourse Analysis, Michael Shane Wunderlich

LSU Master's Theses

This study examined the rebranding of the Brooklyn Nets. A discourse analysis was conducted that observed messages generated by the Brooklyn Nets, selected media sources and fans regarding a number of elements relating to the Brooklyn Nets’ rebrand. Branding is important to businesses and building brand equity and brand associations with the external public is important for businesses looking to succeed in a profit driven world. This is no different for professional sports franchises who also focus on building brand equity and brand associations with sports fans and other members of the general public. By first examining the methods taken …

The Louisiana Recovery School District's Long Term Relationship To Student Dropout And Achievement, Jandel Crutchfield

LSU Doctoral Dissertations

May 14, 2013 marked the 10 year anniversary of the creation of the Louisiana Recovery School District (RSD), the turnaround intervention for low performing public schools. Since 2003, the RSD has grown to include over 80 schools across the state. The purpose of this multilevel longitudinal study was to examine the relationship of the Louisiana Recovery School District to student and school outcomes including risk of dropout and standardized test scores. The dissertation measured these influences over time (2007-2010). The data collected were derived from Louisiana’s Educational Assessment Program (LEAP) and quantitative data on dropout status from the Louisiana Department …

Improving Routines : Self-Monitoring By Adolescents Diagnosed With Attention-Deficit/Hyperactivity Disorder, Meghan Ann Geary

LSU Doctoral Dissertations

Attention-Deficit/Hyperactivity Disorder (ADHD), though commonly diagnosed in childhood, continues to present with problematic symptoms through adolescence and adulthood (Barkley, Fischer, Edelbrock, & Smallish, 1990; Young & Amarasinghe, 2010). Despite the number of adolescents suffering from ADHD and the detrimental effects the symptoms can have on their lives, there is a paucity of research in interventions tailored to this population (Young & Amarasinghe, 2010). Additionally, an even smaller portion of this research addresses daily routines for adolescents, despite findings that maintaining routines are often very difficult for adolescents with ADHD (Bloomquist, 2005; Coghill et al., 2008; Pfiffner et al. 2007; Robin, …

Examining Neotropical Primate Community Structure At Regional And Local Scales : Insights From Taxonomic And Phylogenetic Approaches, Maria Mercedes Gavilanez

LSU Doctoral Dissertations

Understanding mechanisms underlying distribution of biodiversity remains a central issue in ecology. I integrate ecological and phylogenetic information at multiple spatial scales to better understand neotropical primate distribution and community structure. I investigate the variation within species ranges in relation to species richness and patterns of species relatedness. Results suggest positive associations among species throughout their distributions, whereby species tend to present higher richness within their ranges than average richness for the entire taxon. However, comparing empirical distributions to a null model of range cohesion suggests mechanisms other than dispersal are setting a limit to the number of species capable …

Investigating "Experimentalism" : A Case Study Of The Tuba And Its Repertoire, Andrew Brian Larson

LSU Doctoral Dissertations

The extant repertoire for the tuba serves as a landmark for how the tuba was perceived at that moment in time by that composer. This document contains a brief analysis of the tuba “experiment” that has been ongoing since its invention. In addition, it contains a brief parallel case study of the saxophone and how this instrument, invented at about the same time as the tuba, has embraced experimentalism and modern performance. This document contains five major sections. The first provides a brief history of the tuba and its predecessors. The second introduces numerical data representing the performance frequency of …

Optimizing Yield And Crop Nitrogen Response Characterization By Integrating Spectral Reflectance And Agronomic Properties In Sugarcane And Rice, Yumiko Kanke

LSU Doctoral Dissertations

Nitrogen (N) is one of the most important and limiting nutrients in crop production. The best management practices for N fertilization is always challenging due to its dynamic system in the nature. Remote sensing has emerged as one of the most useful technologies in modern agriculture for non-invasive monitoring of plant N status. The objectives of this research were to 1) determine the effect of water background turbidity and depth on red and red-edge reflectance based prediction models for biomass and grain yield in rice, 2) evaluate agronomic parameters of different sugar cane varieties in response to variable levels of …

Nanoindentation Characterization Of Clay Minerals And Clay-Based Hybrid Bio-Geomaterials, Rohit Raj Pant

LSU Doctoral Dissertations

Layered hydrous aluminosilicates are key constituent minerals in rocks, soils, and other parts of the Earth crust. Understanding mechanical properties of these aluminosilicates is crucial for seismic study, stability of parent rocks and geomaterials, and for geophysical subsurface exploration. Recently, growing prospects of clay based nanocomposites have renewed further interest in understanding the fundamental elastic and plastic properties of hydrous aluminosilicates. Their distinct, nanoscale layered crystal structure is known to result in anisotropic responses to loading, however, owing to their tiny sizes; it is a significant challenge to determine the anisotropic properties. There is a little data available in the …

Laser Ablation Sample Transfer For Mass Spectrometry, Sung-Gun Park

LSU Doctoral Dissertations

In this research, a new ambient sampling technique for mass spectrometry was developed that uses an infrared laser to ablate materials under ambient conditions that are captured in a solvent or on a surface. An infrared optical parametric oscillator (OPO) laser system at 3 μm wavelength was focused onto samples for ablation at atmospheric pressure. The ablated materials were transferred to a solvent or surface. For off-line electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) analysis, the ablated material was captured in a static solvent droplet that was deposited on a MALDI target or flow-injected into a nanoelectrospray source. The …

A Novel System To Study Seed Recalcitrance And Dormancy - Comparative Proteomics Between Two Spartina Species, Yi Wang

LSU Doctoral Dissertations

Spartina alterniflora is a dominant salt marsh cordgrass along the U.S. Atlantic and Gulf coasts, and the species is widely used for wetland restoration in Louisiana. S. alterniflora seeds are shed dormant from the mother plant. However, long-term preservation of S. alterniflora seeds is challenging because the seeds are recalcitrant, losing viability when dried below 45% water content. In this dissertation, I investigated the following three aspects of S. alterniflora: recalcitrance, dormancy release by cold stratification and the effect of drying temperature on the critical water content. Comparative proteomics between S. alterniflora and orthodox, desiccation tolerant Spartina pectinata seeds identified …

Silver Nanoparticles As Drug Delivery Systems, Ammar Tahseen Qureshi

LSU Doctoral Dissertations

The goal of this project is to study the potential applications of silver nanoparticles (SNPs) in the medical device and pharmaceutical industries. Bone cements have been used in the orthopedic surgeries for many years to anchor prosthetics while filling up the spaces between the prostheses and bone. Antibiotics are an active component of bone cements but the increasing bacterial resistance to these antibiotics and difficulty of shaping and molding the bone cements increases the need for new antimicrobial biomaterials. Adult stem cell based regenerative therapies have been one of the most widely researched areas of tissue engineering. This is due …

Bioremediation Of Chlorinated Ethanes And Ethenes In Vertical Flow Engineered Wetland Systems, Christopher Akudo

LSU Doctoral Dissertations

Sustainable treatment of chlorinated ethanes and ethenes contaminated groundwater using vertical flow engineered wetland systems were investigated in microcosm and column studies. Experiments on environmental and biogeochemical factors that affect system performance were conducted, and a numerical model involving advection, sorption, and sequential biodegradation was developed to describe the fate and transport of the contaminants of concern in the treatment wetland bed. 1,1-dichloroethane (1,1-DCA) and cis-1,2-dichloroethene (cis-1,2-DCE) were used as the chemicals of interest. The presence of cis-1,2-DCE inhibited dechlorination of 1,1-DCA but cis-1,2-DCE dechlorination was not affected by the presence of 1,1-DCA. Simulation runs showed that the treatment bed …

The Role Of Polyamines In Osmotic Stress Tolerance In Gulf Killifish Fundulus Grandis, Ying Guan

LSU Doctoral Dissertations

Polyamines are a diverse class of aliphatic molecules that are highly polycationic at physiological intracellular pH. Polyamine levels are regulated by the coordinated actions of arginase (Arg), ornithine decarboxylase (Odc), and polyamine oxidase (Pao). Although little is known of their functions in fish, polyamines have been implicated in diverse physiological processes, including RNA transcription, cell growth, cell proliferation, and cell apoptosis. The main objective of this study was to describe the transcription and enzymatic activities of key enzymes for polyamine metabolism, to measure polyamine levels, and to assess putative roles of polyamines in the gills of the Gulf killifish (Fundulus …

An Examination Of Induced Anxiety And Its Interaction With Trait Anxiety On Executive Functioning Tasks, Joseph Harris

LSU Master's Theses

Anxiety is a common human experience which has been shown to have detrimental effects on cognitive abilities, particularly the executive abilities of inhibition, shifting and updating. Previous studies in this area have been highly specific in their focus, leaving gaps in the literature. As a result, the general nature of anxiety’s effect on executive functioning has yet to be fully defined. The current study attempted to establish such a definition by exploring the effects of state anxiety and trait anxiety on each of the executive functions, both in terms of task performance and efficiency. In addition, because working memory has …

Measuring Safety Climate As An Indicator Of Effective Safety And Health Programs In The Construction Industry, Charles Francis Pecquet

LSU Doctoral Dissertations

The purpose of this study was to measure the safety climate, safe behaviors, and EMR, of construction companies in southeastern Louisiana, and to measure selected demographic variables of construction workers employed at these companies. Two hundred and eight workers from twenty nine construction companies agreed to participate in the study. The Safety Climate Survey (SCS) was utilized to measure the safety climate level and safe behaviors of participants and collect selected demographic variables. Additionally, companies were asked to provide their Experience Modification Rates and North American Industry Classification System codes. A six-item Likert-type scale was utilized to measure safety climate …