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Articles 1441 - 1470 of 8029
Full-Text Articles in Entire DC Network
Applying Spatial Video Geonarratives And Physiological Measurements To Explore Perceived Safety In Baton Rouge, Louisiana, Alina Ristea, Michael Leitner, Bernd Resch, Judith Stratmann
Applying Spatial Video Geonarratives And Physiological Measurements To Explore Perceived Safety In Baton Rouge, Louisiana, Alina Ristea, Michael Leitner, Bernd Resch, Judith Stratmann
Faculty Publications
Spatial crime analysis, together with perceived (crime) safety analysis have tremendously benefitted from Geographic Information Science (GISc) and the application of geospatial technology. This research study discusses a novel methodological approach to document the use of emerg-ing geospatial technologies to explore perceived urban safety from the lenses of fear of crime or crime perception in the city of Baton Rouge, USA. The mixed techniques include a survey, spatial video geonarrative (SVG) in the field with study participants, and the extraction of moments of stress (MOS) from biosensing wristbands. This study enrolled 46 participants who completed geonarratives and MOS detection. A …
Streamline-Based Simulation Of Nanoparticle Transport In Field-Scale Heterogeneous Subsurface Systems, Bin Wang, Yin Feng, John Blears, Karsten Thompson, Richard Hughes
Streamline-Based Simulation Of Nanoparticle Transport In Field-Scale Heterogeneous Subsurface Systems, Bin Wang, Yin Feng, John Blears, Karsten Thompson, Richard Hughes
Faculty Publications
Nanoparticle (NP) transport is increasingly relevant to subsurface engineering applications such as aquifer characterization and enhanced oil recovery. An efficient field-scale simulation framework is critical for predicting NP performance and designing subsurface applications. In this work, for the first time, a streamline-based model is presented to simulate NP transport in field-scale subsurface systems with heterogeneous permeability. It considers a series of smart behaviors exhibited by engineered nanoparticles (NPs), including time-triggered encapsulation, retention, formation damage effects and variable nanofluid viscosity. The key methods employed by the algorithm are streamline-based simulation (SLS) and an operator-splitting (OS) technique for modeling NP transport. The …
Click Conjugation Of Boron Dipyrromethene (Bodipy) Fluorophores To Egfr-Targeting Linear And Cyclic Peptides, Tyrslai M. Williams, Nichole E.M. Kaufman, Zehua Zhou, Sitanshu S. Singh, Seetharama D. Jois, Maria Da Graça H. Vicente
Click Conjugation Of Boron Dipyrromethene (Bodipy) Fluorophores To Egfr-Targeting Linear And Cyclic Peptides, Tyrslai M. Williams, Nichole E.M. Kaufman, Zehua Zhou, Sitanshu S. Singh, Seetharama D. Jois, Maria Da Graça H. Vicente
Faculty Publications
Through a simple 1,3-cycloaddition reaction, three BODIPY-peptide conjugates that target the extracellular domain of the epidermal growth factor receptor (EGFR) were prepared and their ability for binding to EGFR was investigated. The peptide ligands K(N3)LARLLT and its cyclic analog cyclo(K(N3)larllt, previously shown to have high affinity for binding to the extracellular domain of EGFR, were conjugated to alkynyl-functionalized BODIPY dyes 1 and 2 via a copper-catalyzed click reaction. This reaction produced conjugates 3, 4, and 5 in high yields (70-82%). In vitro studies using human carcinoma HEp2 cells that overexpress EGFR demonstrated high cellular uptake, particularly for the cyclic peptide …
Zein And Lignin-Based Nanoparticles As Delivery Systems: Pesticide Release And Nanoparticle Health Impact On Soybean Plants, Fallon Polette Salinas Gonzalez
Zein And Lignin-Based Nanoparticles As Delivery Systems: Pesticide Release And Nanoparticle Health Impact On Soybean Plants, Fallon Polette Salinas Gonzalez
LSU Doctoral Dissertations
This research examined the effect of biodegradable, polymeric, lignin-based nanoparticles (LNPs, 113.8±3.4, negatively charged) and zein nanoparticles (ZNP, 141.6±3.9, positively charged) on soybean plant health. The LNPs were synthesized from lignin, covalently linked to poly(lactic-co-glycolic) acid by emulsion evaporation. ZNPs were synthesized by nanoprecipitation. Soybeans grown hydroponically were treated with three concentrations (0.02, 0.2, and 2 mg/ml) of NPs at 28 days after germination. The effect of ZNPs and LNPs on plant health was determined through analysis of root and stem length, chlorophyll concentration, dry biomass of roots and stem, as well as carbon, nitrogen, and micronutrient absorption after 1, …
Development Of The Cell-Free Protein Biomanufacturing Platform For The Therapeutic Human Protein Production And The Topical Delivery Applications Using The Nanosized Hydrogel System, Jeehye Kim
LSU Doctoral Dissertations
Proteins are highly structural polymers, performing an enormous range of roles within organisms. Unlike synthetic polymers, proteins have a significant hierarchical ordering that can be disrupted by many environmental factors, which limits the scale-up manufacturing capability as well as the utilization of proteins as therapeutic agents. In this study, the Cell-Free Protein Synthesis (CFPS) system was developed to enhance the production capacity and applications of the therapeutic proteins. The CFPS is an advanced biosynthetic and genetic-engineered system. It enables the efficient production of proteins when the conventional cell-based protein synthesis systems cannot be applied, and when sophisticated control is required …
The Barley Hvwrky6 Transcription Factor Is Required For Resistance Against Pyrenophora Teres F. Teres, Prabin Tamang, Jonathan K. Richards, Shyam Solanki, Gazala Ameen, Roshan Sharma Poudel, Priyanka Deka, Karl Effertz, Shaun J. Clare, Justin Hegstad, Achintya Bezbaruah, Xuehui Li, Richard D. Horsley, Timothy L. Friesen, Robert S. Brueggeman
The Barley Hvwrky6 Transcription Factor Is Required For Resistance Against Pyrenophora Teres F. Teres, Prabin Tamang, Jonathan K. Richards, Shyam Solanki, Gazala Ameen, Roshan Sharma Poudel, Priyanka Deka, Karl Effertz, Shaun J. Clare, Justin Hegstad, Achintya Bezbaruah, Xuehui Li, Richard D. Horsley, Timothy L. Friesen, Robert S. Brueggeman
Faculty Publications
Barley is an important cereal crop worldwide because of its use in the brewing and distilling industry. However, adequate supplies of quality malting barley are threatened by global climate change due to drought in some regions and excess precipitation in others, which facilitates epidemics caused by fungal pathogens. The disease net form net blotch caused by the necrotrophic fungal pathogen Pyrenophora teres f. teres (Ptt) has emerged as a global threat to barley production and diverse populations of Ptt have shown a capacity to overcome deployed genetic resistances. The barley line CI5791 exhibits remarkably effective resistance to diverse Ptt isolates …
A Microscale Approach To Investigate Breast Cancer Cellular Communication And Migration, Sharif Mohammad Mizanur Rahman
A Microscale Approach To Investigate Breast Cancer Cellular Communication And Migration, Sharif Mohammad Mizanur Rahman
LSU Doctoral Dissertations
Metastatic breast cancer significantly decreases patient survival, with the majority of deaths caused by secondary metastasis. Cancer metastasis is a multi-step process that starts with the detachment of a cancer cell from the primary tumor and ends with establishing a secondary tumor at a distal location. This work's focus was to use an interdisciplinary microscale approach to study how cancer cells respond to neighboring cells and how they migrate in response to chemical gradients. Two distinct devices, a microfluidic device, and a 3D-printed plate insert, were developed to perform co-culture studies to elucidate the impact of ASCs on cancer cell …
A Burkholderia Thailandensis Deda Family Membrane Protein Is Required For Proton Motive Force Dependent Lipid A Modification, Pradip R. Panta, William T. Doerrler
A Burkholderia Thailandensis Deda Family Membrane Protein Is Required For Proton Motive Force Dependent Lipid A Modification, Pradip R. Panta, William T. Doerrler
Faculty Publications
The DedA family is a conserved membrane protein family found in most organisms. A Burkholderia thailandensis DedA family protein, named DbcA, is required for high-level colistin (polymyxin E) resistance, but the mechanism awaits elucidation. Modification of lipopolysaccharide lipid A with the cationic sugar aminoarabinose (Ara4N) is required for colistin resistance and is dependent upon protonmotive force (PMF) dependent transporters. B. thailandensis ΔdbcA lipid A contains only small amounts of Ara4N, likely leading to colistin sensitivity. Two B. thailandensis operons are required for lipid A modification with Ara4N, one needed for biosynthesis of undecaprenyl-P-Ara4N and one for transport of the lipid …
Resistance To Aflatoxin Accumulation In Maize Mediated By Host-Induced Gene Silencing Of Aspergillus Flavus Alkaline Protease And O-Methyltransferase-A Genes, Olanike Omotola Omolehin
Resistance To Aflatoxin Accumulation In Maize Mediated By Host-Induced Gene Silencing Of Aspergillus Flavus Alkaline Protease And O-Methyltransferase-A Genes, Olanike Omotola Omolehin
LSU Doctoral Dissertations
Aspergillus flavus is a soil-borne fungal pathogen that infects maize and produces aflatoxins. In the current study, portions of the alkaline protease (alk) and the O-methyl transferase (omtA) genes, which are key in A. flavus virulence and aflatoxin biosynthesis, respectively, were targeted for suppression through an RNAi (RNA interference) approach known as Host-Induced Gene Silencing (HIGS). Separate RNAi vectors were designed to carry regions of the alk and omtA gene fragments (Alk-RNAi and OmtA-RNAi) and introduced into B104 maize zygotic embryos. Eight and six transformation events were positive for the alk and omtA transgene, respectively. …
Evaluating Us Consumers' Perception Of Foods Made With Cricket Powder, Ryan Paul Ardoin
Evaluating Us Consumers' Perception Of Foods Made With Cricket Powder, Ryan Paul Ardoin
LSU Doctoral Dissertations
Expanding the consumption of edible insects has been proposed as a strategy for global food security due to their sustainability of production and high nutritional value. In the U.S.A., the idea of eating insects is generally unappealing. This research took a methodical approach to understanding U.S. consumers perceptions of insects as food- specifically, products made with cricket powder. Recent consumer-oriented entomophagy research (2015-2020) was reviewed to consolidate understanding of Westerners’ perceptions of edible insects and to evaluate research trends. An online survey of 1,005 U.S. consumers investigated appropriate products for insect protein powder incorporation (based on willingness to try; WTT), …
Small Molecule Inhibitors Of The Bacterioferritin (Bfrb)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas Aeruginosa Cells, Anabel Soldano, Huili Yao, Achala N.D. Punchi Hewage, Kevin Meraz, Joel K. Annor-Gyamfi, Richard A. Bunce, Kevin P. Battaile, Scott Lovell, Mario Rivera
Small Molecule Inhibitors Of The Bacterioferritin (Bfrb)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas Aeruginosa Cells, Anabel Soldano, Huili Yao, Achala N.D. Punchi Hewage, Kevin Meraz, Joel K. Annor-Gyamfi, Richard A. Bunce, Kevin P. Battaile, Scott Lovell, Mario Rivera
Faculty Publications
© 2020 American Chemical Society. Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe3+ in bacterioferritin and its subsequent mobilization as Fe2+ to satisfy metabolic requirements. In Pseudomonas aeruginosa Fe3+ is compartmentalized in bacterioferritin (BfrB), and its mobilization to the cytosol requires binding of a ferredoxin (Bfd) to reduce the stored Fe3+ and release the soluble Fe2+. Blocking the BfrB-Bfd complex in P. aeruginosa by deletion of the bfd gene triggers an irreversible accumulation of Fe3+ in BfrB, concomitant cytosolic iron deficiency and significant impairment …
Censorship Concerns In College Media: A Multiple Case Study Analysis On The Silencing Of Student Journalists, Haley Nicole Matlock
Censorship Concerns In College Media: A Multiple Case Study Analysis On The Silencing Of Student Journalists, Haley Nicole Matlock
LSU Doctoral Dissertations
The aim of this qualitative study was to conduct a multiple case study that provides an analysis of censorship concerns at campus newspapers affiliated with public, four-year universities. Eighteen individuals from seven institutions participated in interviews. Interviewees consisted of former and current student journalists and advisers who worked at university publications where allegations of censorship have occurred within the last decade. The Student Press Law Center routinely investigates claims of censorship and provides pro bono legal counsel to student journalists (Zagier, 2011). While courts commonly sided with students in disagreements regarding free speech, Hazelwood v Kuhlmeier (1988) scaled back freedoms …
Switching Between Singular Points In Non-Pt -Symmetric Multilayer Structures Using Phase-Change Materials, Yin Huang, Lanyan Wang, Yuecheng Shen, Georgios Veronis
Switching Between Singular Points In Non-Pt -Symmetric Multilayer Structures Using Phase-Change Materials, Yin Huang, Lanyan Wang, Yuecheng Shen, Georgios Veronis
Faculty Publications
We investigate the switching between singular points in non-parity-time-symmetric multilayer structures using phase-change materials at the optical communication wavelength. We first show that absorbing singularities can be switched to exceptional points (EPs) in a two-layer structure consisting of a phase-change material layer and a lossy layer by switching the phase-change material Ge2Sb2Te5 (GST) from its crystalline to its amorphous phase. We also show that spectral singularities (SSs) can be switched to EPs in a three-layer structure consisting of a lossless dielectric layer sandwiched between a GST layer and a gain layer by switching the GST from its crystalline to its …
Climate Change Implications For Tidal Marshes And Food Web Linkages To Estuarine And Coastal Nekton, D D. Colombano, S. Y. Litvin, S. L. Ziegler, S. B. Alford, D. D. Colombano, M. A. Barbeau, J. Cebrian, R. M. Connolly, C. A. Currin, L. A. Deegan, J. S. Lesser, C. W. Martin, A. E. Mcdonald, C. Mcluckie, B. H. Morrison, J. W. Pahl, L. W. Risse, J. A. Smith, L. W. Staver, R. Eugene Turner, N. J. Waltham
Climate Change Implications For Tidal Marshes And Food Web Linkages To Estuarine And Coastal Nekton, D D. Colombano, S. Y. Litvin, S. L. Ziegler, S. B. Alford, D. D. Colombano, M. A. Barbeau, J. Cebrian, R. M. Connolly, C. A. Currin, L. A. Deegan, J. S. Lesser, C. W. Martin, A. E. Mcdonald, C. Mcluckie, B. H. Morrison, J. W. Pahl, L. W. Risse, J. A. Smith, L. W. Staver, R. Eugene Turner, N. J. Waltham
Faculty Publications
Climate change is altering naturally fluctuating environmental conditions in coastal and estuarine ecosystems across the globe. Departures from long-term averages and ranges of environmental variables are increasingly being observed as directional changes [e.g., rising sea levels, sea surface temperatures (SST)] and less predictable periodic cycles (e.g., Atlantic or Pacific decadal oscillations) and extremes (e.g., coastal flooding, marine heatwaves). Quantifying the short- and long-term impacts of climate change on tidal marsh seascape structure and function for nekton is a critical step toward fisheries conservation and management. The multiple stressor framework provides a promising approach for advancing integrative, cross-disciplinary research on tidal …
Elevating Dissolved Oxygen - Reflections On Developing And Using Long - Term Data, Nancy N. Rabalais
Elevating Dissolved Oxygen - Reflections On Developing And Using Long - Term Data, Nancy N. Rabalais
Faculty Publications
This prospectus took me about as long to generate as my 36 - year record of working on the issue of northern Gulf of Mexico (nGOM) oxygen deficiency, or so I felt. There was so much to cover, but I focused on the issue of hypoxia on the Louisiana continental shelf from the early 1980s to present and my participation in the research and outreach. Not that I was ignoring other aspects of my academic research career (e.g., stone crab populations and their differences in physiology and larval development along the nGOM coast; settlement of crab megalopae, especially blue crabs, …
Astronomical Tide And Storm Surge Signals Observed In An Isolated Inland Maar Lake Near The Coast, Mingming Li, Chunyan Li, Lingling Xie, Wei Huang, Quanan Zheng, Keyi Tan, Yingbin Hong
Astronomical Tide And Storm Surge Signals Observed In An Isolated Inland Maar Lake Near The Coast, Mingming Li, Chunyan Li, Lingling Xie, Wei Huang, Quanan Zheng, Keyi Tan, Yingbin Hong
Faculty Publications
Aimed at the explanation of clear tidal signal and storm surge signals in a closed inland lake near the coast (the Huguangyan Lake), this work uses a combined approach with observations and model experiments. Huguangyan Lake is a closed inland freshwater coneless volcanic crater lake near the coast in tropical southern China, less than 5 km from an estuary. It has a diameter of about 1.5 km and relatively deep water of up to 20 m. Bottom pressure was measured from an acoustic Doppler current profiler (ADCP) for 10 days in September 2018 and 10 days in January 2019. The …
The Impact Of Covid-19 On The Use Of Academic Library Resources, Ruth Connell, Lisa Wallis, David Comeaux
The Impact Of Covid-19 On The Use Of Academic Library Resources, Ruth Connell, Lisa Wallis, David Comeaux
Faculty Publications
The COVID-19 pandemic has greatly impacted higher education, including academic libraries. This paper compares the use of library resources (including interlibrary loan, website and discovery tool pageviews, database use, patron interactions, etc.) at three university libraries before and after the pandemic. The latter part of the 2019 and 2020 spring semesters are the timeframes of focus, although two control timeframes from earlier in those semesters are used to determine how the semesters differed when the coronavirus was not a factor. The institutions experienced similar patterns of use across many metrics.
Lsu General Catalog 2021-2022, Louisiana State University And Agricultural And Mechanical College
Lsu General Catalog 2021-2022, Louisiana State University And Agricultural And Mechanical College
LSU General Catalog
The LSU General Catalog describes all undergraduate and graduate departments and programs with degree requirements and courses offered for each one. The LSU General Catalog includes information on registration and financial aid as well as academic services offered to all students.
Louisiana Agriculture Winter, 2021, Lsu Agcenter
Louisiana Agriculture Winter, 2021, Lsu Agcenter
Louisiana Agriculture
No abstract provided.
Northeast- Winter 2021, Lsu Agcenter
Northwest - Winter 2021, Lsu Agcenter
Central- Winter 2021, Lsu Agcenter
Southwest- Winter 2021, Lsu Agcenter
Southeast- Winter 2021, Lsu Agcenter
Bats And Humans During Thesars-Cov-2outbreak: The Case Of Bat-Coronaviruses From Mexico, P Colunga-Salas, G Hernandez-Canchola
Bats And Humans During Thesars-Cov-2outbreak: The Case Of Bat-Coronaviruses From Mexico, P Colunga-Salas, G Hernandez-Canchola
Faculty Publications
The novelSARS-CoV-2coronavirus has attracted attention due to the high number of human cases around the world. It has been proposed that this virus originated in bats, possibly transmitted to humans by an intermediate host, making bats a group of great interest during this outbreak. Almost 10% of the world's bat species inhabit Mexico, and 14 previous novel CoVs have been recorded in Mexican bats. However, the phylogenetic relationships between these viruses and the novel coronavirus are unknown. The aim of this communication was therefore to describe the phylogenetic relationships between Mexican bat-CoVs andSARS-CoV-2. We showed that Mexican bat-CoVs sequences are …
The Interplay Between Environmental Exposures And Covid-19 Risks In The Health Of Children, P D. Sly, B A. Trottier, C M. Bulka, S A. Cormier, P D. Sly, R C. Fry, K W. Kim, S Kleeberger, P Kumar, P J. Landrigan, K L. Carlsen, A Pascale, F Polack, M Ruchirawat, H J. Zar, W A. Suk
The Interplay Between Environmental Exposures And Covid-19 Risks In The Health Of Children, P D. Sly, B A. Trottier, C M. Bulka, S A. Cormier, P D. Sly, R C. Fry, K W. Kim, S Kleeberger, P Kumar, P J. Landrigan, K L. Carlsen, A Pascale, F Polack, M Ruchirawat, H J. Zar, W A. Suk
Faculty Publications
Background: An unusual feature of SARS-Cov-2 infection and the COVID-19 pandemic is that children are less severely affected than adults. This is especially paradoxical given the epidemiological links between poor air quality and increased COVID-19 severity in adults and that children are generally more vulnerable than adults to the adverse consequences of air pollution. Objectives: To identify gaps in knowledge about the factors that protect children from severe SARS-Cov-2 infection even in the face of air pollution, and to develop a transdisciplinary research strategy to address these gaps. Methods: An international group of researchers interested in children's environmental health was …
The Impact Of Covid-19 On Consumer Food Wastejel Codes, B E. Roe, K Bender, D Y. Qi
The Impact Of Covid-19 On Consumer Food Wastejel Codes, B E. Roe, K Bender, D Y. Qi
Faculty Publications
Perhaps no phenomenon has so quickly and radically altered household production parameters and daily food patterns as the onset of the COVID-19 pandemic. We contemplate the immediate and longer-term implications of this public health crisis on the amount of food wasted by consumers. We conclude that the pandemic and its aftermath may improve household skills and management practices in a manner that reduces day-to-day household food waste. However, pandemic-driven disruptions may induce larger intermittent purges of food due to changes in work patterns and food service and food retailing availability. We recommend several steps to reduce waste as the pandemic …
Telehealth And Autism Prior To And In The Age Of Covid-19: A Systematic And Critical Review Of The Last Decade, K S. Ellison, J Guidry, P Picou, P Adenuga, K S. Ellison
Telehealth And Autism Prior To And In The Age Of Covid-19: A Systematic And Critical Review Of The Last Decade, K S. Ellison, J Guidry, P Picou, P Adenuga, K S. Ellison
Faculty Publications
There has been growing interest in the use of telehealth; however, the COVID-19 pandemic and the subsequent isolation and restrictions placed on in-person services have fast-tracked implementation needs for these services. Individuals with autism spectrum disorder (ASD) have been particularly affected due to the often-intensive service needs required by this population. As a result, the aim of this review was to examine the evidence base, methodology, and outcomes of studies that have used telehealth for assessment and/or intervention with children and adolescents with ASD as well as their families over the last decade. Further, the goal is to highlight the …
Experimental Re-Infected Cats Do Not Transmit Sars-Cov-2, N N. Gaudreault, M Carossino, I Morozov, J D. Trujillo, N N. Gaudreault, D W. Madden, K Cool, B L. Artiaga, C Mcdowell, D Bold, V Balaraman, T Kwon, W J. Ma, J Henningson, D W. Wilson, W C. Wilson, U C. Balasuriya, A Garcia-Sastre, J A. Richt
Experimental Re-Infected Cats Do Not Transmit Sars-Cov-2, N N. Gaudreault, M Carossino, I Morozov, J D. Trujillo, N N. Gaudreault, D W. Madden, K Cool, B L. Artiaga, C Mcdowell, D Bold, V Balaraman, T Kwon, W J. Ma, J Henningson, D W. Wilson, W C. Wilson, U C. Balasuriya, A Garcia-Sastre, J A. Richt
Faculty Publications
SARS-CoV-2 is the causative agent of COVID-19 and responsible for the current global pandemic. We and others have previously demonstrated that cats are susceptible to SARS-CoV-2 infection and can efficiently transmit the virus to naive cats. Here, we address whether cats previously exposed to SARS-CoV-2 can be re-infected with SARS-CoV-2. In two independent studies, SARS-CoV-2-infected cats were re-challenged with SARS-CoV-2 at 21 days post primary challenge (DPC) and necropsies performed at 4, 7 and 14 days post-secondary challenge (DP2C). Sentinels were co-mingled with the re-challenged cats at 1 DP2C. Clinical signs were recorded, and nasal, oropharyngeal, and rectal swabs, blood, …
Online-Delivered Group And Personal Exercise Programs To Support Low Active Older Adults' Mental Health During The Covid-19 Pandemic: Randomized Controlled Trial, M R. Beauchamp, R M. Hulteen, G R. Ruissen, Y Liu, M R. Beauchamp, C M. Wierts, K J. Waldhauser, S H. Harden, E Puterman
Online-Delivered Group And Personal Exercise Programs To Support Low Active Older Adults' Mental Health During The Covid-19 Pandemic: Randomized Controlled Trial, M R. Beauchamp, R M. Hulteen, G R. Ruissen, Y Liu, M R. Beauchamp, C M. Wierts, K J. Waldhauser, S H. Harden, E Puterman
Faculty Publications
Background: In response to the COVID-19 pandemic, experts in mental health science emphasized the importance of developing and evaluating approaches to support and maintain the mental health of older adults. Objective: The aim of this study was to assess whether a group-based exercise program relative to a personal exercise program (both delivered online) and waitlist control (WLC) can improve the psychological health of previously low active older adults during the early stages of the COVID-19 pandemic. Methods: The Seniors COVID-19 Pandemic and Exercise (SCOPE) trial was a 3-arm, parallel randomized controlled trial conducted between May and September 2020 in which …