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Articles 1141 - 1170 of 8029
Full-Text Articles in Entire DC Network
From Merging Frameworks To Merging Stars: Experiences Using Hpx, Kokkos And Simd Types, Gregor Dais, Srinivas Yadav Singanaboina, Patrick Diehl, Hartmut Kaiser, Dirk Pfluger
From Merging Frameworks To Merging Stars: Experiences Using Hpx, Kokkos And Simd Types, Gregor Dais, Srinivas Yadav Singanaboina, Patrick Diehl, Hartmut Kaiser, Dirk Pfluger
Faculty Publications
Octo-Tiger, a large-scale 3D AMR code for the merger of stars, uses a combination of HPX, Kokkos and explicit SIMD types, aiming to achieve performance-portability for a broad range of heterogeneous hardware. However, on A64FX CPUs, we encountered several missing pieces, hindering performance by causing problems with the SIMD vectorization. Therefore, we add std:experimental:simd as an option to use in Octo-Tiger's Kokkos kernels alongside Kokkos SIMD, and further add a new SVE (Scalable Vector Extensions) SIMD backend. Additionally, we amend missing SIMD implementations in the Kokkos kernels within Octo-Tiger's hydro solver. We test our changes by running Octo-Tiger on three …
Analyzing Tweeting Patterns And Public Engagement On Twitter During The Recognition Period Of The Covid-19 Pandemic: A Study Of Two U.S. States, Misbah Ul Hoque, Kisung Lee, Jessica L. Beyer, Sara R. Curran, Katie S. Gonser, Nina S.N. Lam, Volodymyr V. Mihunov, Kejin Wang
Analyzing Tweeting Patterns And Public Engagement On Twitter During The Recognition Period Of The Covid-19 Pandemic: A Study Of Two U.S. States, Misbah Ul Hoque, Kisung Lee, Jessica L. Beyer, Sara R. Curran, Katie S. Gonser, Nina S.N. Lam, Volodymyr V. Mihunov, Kejin Wang
Faculty Publications
The abundance of available information on social media can provide invaluable insights into people's responses to health information and public health guidance concerning COVID-19. This study examines tweeting patterns and public engagement on Twitter, as forms of social media, related to public health messaging in two U.S. states (Washington and Louisiana) during the early stage of the pandemic. We analyze more than 7M tweets and 571K COVID-19-related tweets posted by users in the two states over the first 25 days of the pandemic in the U.S. (Feb. 23, 2020, to Mar. 18, 2020). We also qualitatively code and examine 460 …
Maternal Mindful Eating As A Target For Improving Metabolic Outcomes In Pregnant Women With Obesity, Karen L. Lindsay, Jasper Most, Kerrie Buehler, Maryam Kebbe, Abby D. Altazan, Leanne M. Redman
Maternal Mindful Eating As A Target For Improving Metabolic Outcomes In Pregnant Women With Obesity, Karen L. Lindsay, Jasper Most, Kerrie Buehler, Maryam Kebbe, Abby D. Altazan, Leanne M. Redman
Clinical Research Faculty Publications
Background: Maternal diet and eating behaviors have the potential to influence the metabolic milieu in pregnancies complicated by obesity, with implications for the developmental programming of offspring obesity. Emerging evidence suggests that mindfulness during eating may influence metabolic health in non-pregnant populations, but its effects in the context of pregnancy is less well understood. This study explored the individual and combined effects of mindful eating and diet quality on metabolic outcomes among pregnant women with obesity. Methods: In 46 pregnant women (body mas index >30 kg/m2) enrolled in the MomEE observational study, mindful eating (Mindful Eating Questionnaire, MEQ) and energy-adjusted …
See You In The Funny Pages: Forms And Aesthetics Of Newspaper Comic Strips In Bill Watterson's Calvin And Hobbes, Jack Mallard
See You In The Funny Pages: Forms And Aesthetics Of Newspaper Comic Strips In Bill Watterson's Calvin And Hobbes, Jack Mallard
LSU Doctoral Dissertations
This project looks at how Bill Watterson’s aesthetics and his employment of the comics apparatus, as well as his advocacy for learning the history of the formal development (and decline) of the newspaper comic strip, influence Calvin and Hobbes’ approach to art, family, education, and other cultural topics. By adapting Thierry Groensteen’s theory of spatio-topia, a term describing comics’ ability to provoke meaning from how graphic, verbal, and structural elements inhabit space and relate to one another within space, I demonstrate how Bill Watterson’s quality as a comics artist comes as much from his ability to activate spatio-topic potentials …
A Global Ocean Oxygen Database And Atlas For Assessing And Predicting Deoxygenation And Ocean Health In The Open And Coastal Ocean, Marilaure Grégoire, Véronique Garçon, Hernan Garcia, Denise Breitburg, Kirsten Isensee, Andreas Oschlies, Maciej Telszewski, Alexander Barth, Henry C. Bittig, Jacob Carstensen, Thierry Carval, Fei Chai, Francisco Chavez, Daniel Conley, Laurent Coppola, Sean Crowe, Kim Currie, Minhan Dai, Bruno Deflandre, Boris Dewitte, Robert Diaz, Emilio Garcia-Robledo, Denis Gilbert, Alessandra Giorgetti, Ronnie Glud, Dimitri Gutierrez, Shigeki Hosoda, Masao Ishii, Gil Jacinto, Chris Langdon, Siv K. Lauvset, Lisa A. Levin, Karin E. Limburg
A Global Ocean Oxygen Database And Atlas For Assessing And Predicting Deoxygenation And Ocean Health In The Open And Coastal Ocean, Marilaure Grégoire, Véronique Garçon, Hernan Garcia, Denise Breitburg, Kirsten Isensee, Andreas Oschlies, Maciej Telszewski, Alexander Barth, Henry C. Bittig, Jacob Carstensen, Thierry Carval, Fei Chai, Francisco Chavez, Daniel Conley, Laurent Coppola, Sean Crowe, Kim Currie, Minhan Dai, Bruno Deflandre, Boris Dewitte, Robert Diaz, Emilio Garcia-Robledo, Denis Gilbert, Alessandra Giorgetti, Ronnie Glud, Dimitri Gutierrez, Shigeki Hosoda, Masao Ishii, Gil Jacinto, Chris Langdon, Siv K. Lauvset, Lisa A. Levin, Karin E. Limburg
Faculty Publications
In this paper, we outline the need for a coordinated international effort toward the building of an open-access Global Ocean Oxygen Database and ATlas (GO2DAT) complying with the FAIR principles (Findable, Accessible, Interoperable, and Reusable). GO2DAT will combine data from the coastal and open ocean, as measured by the chemical Winkler titration method or by sensors (e.g., optodes, electrodes) from Eulerian and Lagrangian platforms (e.g., ships, moorings, profiling floats, gliders, ships of opportunities, marine mammals, cabled observatories). GO2DAT will further adopt a community-agreed, fully documented metadata format and a consistent quality control (QC) procedure and quality flagging (QF) system. GO2DAT …
Ethnic Diversity And Preferred Leadership Attributes: A Quantitative Analysis With Secondary Use Of Qualitative Data, Maha Kumaran, Keith Walker, Samson Wakibi
Ethnic Diversity And Preferred Leadership Attributes: A Quantitative Analysis With Secondary Use Of Qualitative Data, Maha Kumaran, Keith Walker, Samson Wakibi
Library Diversity and Residency Studies
The broad diversity and leadership landscape in the Canadian academic librarianship was assessed using a survey. The survey was designed using REDCap. It was piloted, translated into French, tested again, and electronically distributed via REDCap to English and French-speaking librarians across Canadian academic institutions. This paper represents a secondary analysis of collected data to determine whether the ethnic backgrounds of librarians have any influence on what they view as the most or least essential attributes in a leader. Secondary use of data means using data for a different purpose (from what it was collected for), sometimes by the same researcher …
Using The Book How To Be An Antiracist In Library Dei Community Programs: Bringing Equity, Diversity, And Inclusion To The Community, Nakia Hoskins
Using The Book How To Be An Antiracist In Library Dei Community Programs: Bringing Equity, Diversity, And Inclusion To The Community, Nakia Hoskins
Library Diversity and Residency Studies
This brief article provides an overview of a program in which the University of North Carolina at Greensboro library hosted a series of book club conversations about racism utilizing the book How to Be an Antiracist by Ibram X. Kendi. The article concludes with some observations and suggestions.
Variedades. Second Edition. Intermediate/ Advanced Spanish Conversation, Carmela V. Mattza
Variedades. Second Edition. Intermediate/ Advanced Spanish Conversation, Carmela V. Mattza
Faculty Publications
VARIEDADES. Second Edition. Intermediate/ Advanced Spanish Conversation is a textbook for the student at the intermediate / advanced intermediate level. Through audiovisual activities, the student is expected to put their previous knowledge into practice and improve their ability to understand, write, listen, and speak in Spanish. VARIEDADES offers communicative activities that can be easily adapted into courses of different levels. In addition, it offers an appendix of activities with films and a Spanish grammar section that by subject directs the student to electronic databases that are freely accessible or are part of the Open Access platform.
Mutations In A Barley Cytochrome P450 Gene Enhances Pathogen Induced Programmed Cell Death And Cutin Layer Instability, Gazala Ameen, Shyam Solanki, Lauren Sager-Bittara, Jonathan Richards, Prabin Tamang, Timothy L. Friesen, Robert S. Brueggeman
Mutations In A Barley Cytochrome P450 Gene Enhances Pathogen Induced Programmed Cell Death And Cutin Layer Instability, Gazala Ameen, Shyam Solanki, Lauren Sager-Bittara, Jonathan Richards, Prabin Tamang, Timothy L. Friesen, Robert S. Brueggeman
Faculty Publications
Disease lesion mimic mutants (DLMMs) are characterized by the spontaneous development of necrotic spots with various phenotypes designated as necrotic (nec) mutants in barley. The nec mutants were traditionally considered to have aberrant regulation of programmed cell death (PCD) pathways, which have roles in plant immunity and development. Most barley nec3 mutants express cream to orange necrotic lesions contrasting them from typical spontaneous DLMMs that develop dark pigmented lesions indicative of serotonin/phenolics deposition. Barley nec3 mutants grown under sterile conditions did not exhibit necrotic phenotypes until inoculated with adapted pathogens, suggesting that they are not typical DLMMs. The F2 progeny …
Whole Genome Comparisons Reveal Panmixia Among Fall Armyworm (Spodoptera Frugiperda) From Diverse Locations, Katrina A. Schlum, Kurt Lamour, Caroline Placidi De Bortoli, Rahul Banerjee, Robert Meagher, Eliseu Pereira, Maria Gabriela Murua, Gregory A. Sword, Ashley E. Tessnow, Diego Viteri Dillon, Angela M. Linares Ramirez, Komivi S. Akutse, Rebecca Schmidt-Jeffris, Fangneng Huang, Dominic Reisig, Scott J. Emrich, Juan Luis Jurat-Fuentes
Whole Genome Comparisons Reveal Panmixia Among Fall Armyworm (Spodoptera Frugiperda) From Diverse Locations, Katrina A. Schlum, Kurt Lamour, Caroline Placidi De Bortoli, Rahul Banerjee, Robert Meagher, Eliseu Pereira, Maria Gabriela Murua, Gregory A. Sword, Ashley E. Tessnow, Diego Viteri Dillon, Angela M. Linares Ramirez, Komivi S. Akutse, Rebecca Schmidt-Jeffris, Fangneng Huang, Dominic Reisig, Scott J. Emrich, Juan Luis Jurat-Fuentes
Faculty Publications
Background: The fall armyworm (Spodoptera frugiperda (J.E. Smith)) is a highly polyphagous agricultural pest with long-distance migratory behavior threatening food security worldwide. This pest has a host range of > 80 plant species, but two host strains are recognized based on their association with corn (C-strain) or rice and smaller grasses (R-strain). The population genomics of the United States (USA) fall armyworm remains poorly characterized to date despite its agricultural threat. Results: In this study, the population structure and genetic diversity in 55 S. frugiperda samples from Argentina, Brazil, Kenya, Puerto Rico and USA were surveyed to further our understanding of …
Behavioral Characteristics And Self-Reported Health Status Among 2029 Adults Consuming A "Carnivore Diet", Belinda S. Lennerz, Jacob T. Mey, Owen H. Henn, David S. Ludwig
Behavioral Characteristics And Self-Reported Health Status Among 2029 Adults Consuming A "Carnivore Diet", Belinda S. Lennerz, Jacob T. Mey, Owen H. Henn, David S. Ludwig
Division of Basic Science Faculty Publications
Background: The "carnivore diet,"based on animal foods and excluding most or all plant foods, has attracted recent popular attention. However, little is known about the health effects and tolerability of this diet, and concerns for nutrient deficiencies and cardiovascular disease risk have been raised. Objectives: We obtained descriptive data on the nutritional practices and health status of a large group of carnivore diet consumers. Methods: A social media survey was conducted 30 March-24 June, 2020 among adults self-identifying as consuming a carnivore diet for ≥6 mo. Survey questions interrogated motivation, dietary intake patterns, symptoms suggestive of nutritional deficiencies or other …
Impact Of Acute Exercise On Peripheral Blood Mononuclear Cells Nutrient Sensing And Mitochondrial Oxidative Capacity In Healthy Young Adults, Bailey Theall, James Stampley, Eunhan Cho, Joshua Granger, Neil M. Johannsen, Brian A. Irving, Guillaume Spielmann
Impact Of Acute Exercise On Peripheral Blood Mononuclear Cells Nutrient Sensing And Mitochondrial Oxidative Capacity In Healthy Young Adults, Bailey Theall, James Stampley, Eunhan Cho, Joshua Granger, Neil M. Johannsen, Brian A. Irving, Guillaume Spielmann
Clinical Research Faculty Publications
Regular exercise is associated with changes in peripheral blood mononuclear cell (PBMC) proportions that have enhanced effector functions in young and old adults; however, the effects of acute exercise on PBMC nutrient sensors and metabolic function in active young adults is unknown. To fill this gap, activation status and nutrient-sensing mechanisms of PBMCs isolated from 21 healthy active adults (20–35 yr; 36.5 ± 6.3 V̇O2peak) were characterized before and after 30 min of moderate-to-vigorous cycling (65%–75% V̇O2peak). In addition, changes in PBMC mitochondrial respiratory function in response to exercise were assessed using high-resolution respirometry. There was an increase in the …
Biological And Environmental Influences On Motor Coordination In Peruvian Children And Adolescents, Sara Pereira, Alcibíades Bustamante, Carla Santos, Donald Hedeker, Go Tani, Rui Garganta, Olga Vasconcelos, Adam Baxter-Jones, Peter T. Katzmarzyk, José Maia
Biological And Environmental Influences On Motor Coordination In Peruvian Children And Adolescents, Sara Pereira, Alcibíades Bustamante, Carla Santos, Donald Hedeker, Go Tani, Rui Garganta, Olga Vasconcelos, Adam Baxter-Jones, Peter T. Katzmarzyk, José Maia
Population and Public Health Science Faculty Publications
This study investigated the associations between biological and environmental factors and gross-motor coordination (GMC) in Peruvian children and adolescents. The sample comprised 7401 boys and girls, aged 6–14 years, recruited from three geographical regions: sea-level, Amazon and high-altitude. Biological variables included age, sex, height, BMI, physical fitness, stunting, and maturational status. Environmental influences included geographical region and school characteristics. Gross-motor coordination was tested with the Körperkoordinationstest für Kinder and the data analyzed by multilevel logistic regression. Results showed a high prevalence of below normal GMC scores. Sex, age, geographical area, biological maturation, BMI (normal versus overweight/obesity), and stunting were all …
The Acute Transcriptional Responses To Dietary Methionine Restriction Are Triggered By Inhibition Of Ternary Complex Formation And Linked To Erk1/2, Mtor, And Atf4, Kirsten P. Stone, Sujoy Ghosh, Jean Paul Kovalik, Manda Orgeron, Desiree Wanders, Landon C. Sims, Thomas W. Gettys
The Acute Transcriptional Responses To Dietary Methionine Restriction Are Triggered By Inhibition Of Ternary Complex Formation And Linked To Erk1/2, Mtor, And Atf4, Kirsten P. Stone, Sujoy Ghosh, Jean Paul Kovalik, Manda Orgeron, Desiree Wanders, Landon C. Sims, Thomas W. Gettys
Division of Basic Science Faculty Publications
The initial sensing of dietary methionine restriction (MR) occurs in the liver where it activates an integrated stress response (ISR) that quickly reduces methionine utilization. The ISR program is regulated in part by ATF4, but ATF4’s prototypical upstream regulator, eIF2α, is not acutely activated by MR. Bioinformatic analysis of RNAseq and metabolomics data from liver samples harvested 3 h and 6 h after initiating MR shows that general translation is inhibited at the level of ternary complex formation by an acute 50% reduction of hepatic methionine that limits formation of initiator methionine tRNA. The resulting ISR is induced by selective …
Ale Beer Containing Free And Immobilized Lactobacillus Brevis, A Potential Delivery System For Probiotics, Kriza Faye Calumba, Vondel Reyes, Franklin Bonilla, Elio Villasmil, Subramaniam Sathivel
Ale Beer Containing Free And Immobilized Lactobacillus Brevis, A Potential Delivery System For Probiotics, Kriza Faye Calumba, Vondel Reyes, Franklin Bonilla, Elio Villasmil, Subramaniam Sathivel
Faculty Publications
Abstract: Probiotics in ale beer may be attractive to health-conscious consumers. However, beer conditions may decrease probiotic viability. Powder produced from durian (Durio zibethinus) rind, a by-product that is currently unutilized, can be used for the immobilization of probiotics. MRS medium was incubated with Lactobacillus brevis and periodically sampled to obtain the growth curve. Ale beer with free L. brevis and cells immobilized in durian rind powder was produced and separately assessed during storage at 21 °C for 24 days. The physico-chemical parameters of both beers did not differ significantly. Durian rind powder conferred protection up to 12 days of …
Household Chaos, Family Routines, And Young Child Movement Behaviors In The U.S. During The Covid-19 Outbreak: A Cross-Sectional Study, Chelsea L. Kracht, Peter T. Katzmarzyk, Amanda E. Staiano
Household Chaos, Family Routines, And Young Child Movement Behaviors In The U.S. During The Covid-19 Outbreak: A Cross-Sectional Study, Chelsea L. Kracht, Peter T. Katzmarzyk, Amanda E. Staiano
Population and Public Health Science Faculty Publications
Background: The home environment is an important facilitator of young child movement behaviors, including physical activity (PA), sleep, and screen-time. Household chaos, characterized by crowding, noise, and disorder in the home, may hinder efforts to obtain adequate amounts of movement behaviors. The COVID-19 outbreak impacted many families, and social distancing during this time may create conditions for more household chaos. Family routines can help establish order in the home and encourage an appropriate balance of movement behaviors, such as less screen-time and more sleep. The purpose of this study was to evaluate the association between household chaos and young child …
Adolescents’ Sedentary Time, Affect, And Contextual Factors: An Ecological Momentary Assessment Study, Chelsea L. Kracht, Robbie A. Beyl, Jaclyn P. Maher, Peter T. Katzmarzyk, Amanda E. Staiano
Adolescents’ Sedentary Time, Affect, And Contextual Factors: An Ecological Momentary Assessment Study, Chelsea L. Kracht, Robbie A. Beyl, Jaclyn P. Maher, Peter T. Katzmarzyk, Amanda E. Staiano
Population and Public Health Science Faculty Publications
Background: Few adolescents achieve sufficient levels of physical activity, and many are spending most of their time in sedentary behavior. Affective response following sedentary time may influence motivation to remain sedentary. Ecological Momentary Assessment (EMA) is a real-time data capture methodology that can be used to identify factors influencing sedentary time, such as the context of the home setting, and resulting affective state within a free-living setting. The purpose of this study was to evaluate the relationship between context at home and adolescent sedentary time, and the relationship of sedentary time and subsequent affect. Methods: Adolescents (n = 284; 10–16 …
Global Effect Of Covid-19 Pandemic On Physical Activity, Sedentary Behaviour And Sleep Among 3- To 5-Year-Old Children: A Longitudinal Study Of 14 Countries, Anthony D. Okely, Katharina E. Kariippanon, Hongyan Guan, Ellie K. Taylor, Thomas Suesse, Penny L. Cross, Kar Hau Chong, Adang Suherman, Ali Turab, Amanda E. Staiano, Amy S. Ha, Asmaa El Hamdouchi, Aqsa Baig, Bee Koon Poh, Borja Del Pozo-Cruz, Cecilia H.S. Chan, Christine Delisle Nyström, Denise Koh, E. Kipling Webster, Himangi Lubree, Hong Kim Tang, Issad Baddou, Jesus Del Pozo-Cruz, Jyh Eiin Wong, Kuston Sultoni, Maria Nacher, Marie Löf, Mingming Cui, Mohammad Sorowar Hossain, P. W.Prasad Chathurangana, Uddhavi Kand, V. P.Pujitha Wickramasinghe, Rebecca Calleia, Shameema Ferdous
Global Effect Of Covid-19 Pandemic On Physical Activity, Sedentary Behaviour And Sleep Among 3- To 5-Year-Old Children: A Longitudinal Study Of 14 Countries, Anthony D. Okely, Katharina E. Kariippanon, Hongyan Guan, Ellie K. Taylor, Thomas Suesse, Penny L. Cross, Kar Hau Chong, Adang Suherman, Ali Turab, Amanda E. Staiano, Amy S. Ha, Asmaa El Hamdouchi, Aqsa Baig, Bee Koon Poh, Borja Del Pozo-Cruz, Cecilia H.S. Chan, Christine Delisle Nyström, Denise Koh, E. Kipling Webster, Himangi Lubree, Hong Kim Tang, Issad Baddou, Jesus Del Pozo-Cruz, Jyh Eiin Wong, Kuston Sultoni, Maria Nacher, Marie Löf, Mingming Cui, Mohammad Sorowar Hossain, P. W.Prasad Chathurangana, Uddhavi Kand, V. P.Pujitha Wickramasinghe, Rebecca Calleia, Shameema Ferdous
Population and Public Health Science Faculty Publications
Background: The restrictions associated with the 2020 COVID-19 pandemic has resulted in changes to young children’s daily routines and habits. The impact on their participation in movement behaviours (physical activity, sedentary screen time and sleep) is unknown. This international longitudinal study compared young children’s movement behaviours before and during the COVID-19 pandemic. Methods: Parents of children aged 3–5 years, from 14 countries (8 low- and middle-income countries, LMICs) completed surveys to assess changes in movement behaviours and how these changes were associated with the COVID-19 pandemic. Surveys were completed in the 12 months up to March 2020 and again between …
E-&Mhealth Interventions Targeting Nutrition, Physical Activity, Sedentary Behavior, And/Or Obesity Among Children: A Scoping Review Of Systematic Reviews And Meta-Analyses, Chelsea L. Kracht, Melinda Hutchesson, Mavra Ahmed, Andre Matthias Müller, Lee M. Ashton, Hannah M. Brown, Ann Desmet, Carol A. Maher, Chelsea E. Mauch, Corneel Vandelanotte, Zenong Yin, Megan Whatnall, Camille E. Short, Amanda E. Staiano
E-&Mhealth Interventions Targeting Nutrition, Physical Activity, Sedentary Behavior, And/Or Obesity Among Children: A Scoping Review Of Systematic Reviews And Meta-Analyses, Chelsea L. Kracht, Melinda Hutchesson, Mavra Ahmed, Andre Matthias Müller, Lee M. Ashton, Hannah M. Brown, Ann Desmet, Carol A. Maher, Chelsea E. Mauch, Corneel Vandelanotte, Zenong Yin, Megan Whatnall, Camille E. Short, Amanda E. Staiano
Population and Public Health Science Faculty Publications
Childhood obesity is a public health concern. Electronic and mobile health (e-&mHealth) approaches can facilitate the delivery of interventions for obesity prevention and treatment. Synthesizing reviews of e-&mHealth interventions to improve weight and weight-related behaviors (physical activity, sedentary behavior, and diet) is useful to characterize the current scope of the literature and identify opportunities for future reviews and studies. Using a scoping review methodology, we aimed to evaluate the breadth and methodological quality of systematic reviews and meta-analyses of e-&mHealth interventions targeting weight and weight-related behaviors in children and adolescents aged < 19 years. A systematic search of seven databases was conducted, including reviews published between 2000 and 2019. Review characteristics were extracted, and methodological quality was assessed using the AMSTAR 2 tool. Forty-five systematic reviews and meta-analyses were included. All reviews evaluated intervention efficacy (100%), but few assessed other aspects (20% in total) such as cost-effectiveness. Smartphone applications (47%), text messages (44%), and websites (35%) were the main modalities. Weight (60%), physical activity (51%), and diet (44%) were frequently assessed, unlike sedentary behavior (8%). Most reviews were rated as having critically low or low methodological quality (97%). Reviews that identify the effective active ingredients of interventions and explore metrics beyond efficacy are recommended.
A Link Between Ph Homeostasis And Colistin Resistance In Bacteria, Pradip R. Panta, William T. Doerrler
A Link Between Ph Homeostasis And Colistin Resistance In Bacteria, Pradip R. Panta, William T. Doerrler
Faculty Publications
Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme colistin resistance of Burkholderia thailandensis. The molecular mechanisms behind this remain unclear. Here, we report that ∆dbcA displays alkaline pH/bicarbonate sensitivity and propose a role of DbcA in extreme colistin resistance of B. thailandensis by maintaining cytoplasmic pH homeostasis. We found that alkaline pH or presence of sodium bicarbonate displays a synergistic effect with colistin against not only extremely colistin resistant species like B. thailandensis and Serratia marcescens, but also a majority of Gram-negative and Gram-positive bacteria tested, suggesting …
Staging Tau Pathology With Tau Pet In Alzheimer’S Disease: A Longitudinal Study, Shi Dong Chen, Jia Ying Lu, Hong Qi Li, Yu Xiang Yang, Jie Hui Jiang, Mei Cui, Chuan Tao Zuo, Lan Tan, Qiang Dong, Jin Tai Yu, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Richard J. Perrin, Leslie M. Shaw, Maria Carrillo, William Potter, Lisa Barnes, Marie Bernard, Hector González, Carole Ho, John K. Hsiao, Jonathan Jackson, Eliezer Masliah, Donna Masterman, Ozioma Okonkwo
Staging Tau Pathology With Tau Pet In Alzheimer’S Disease: A Longitudinal Study, Shi Dong Chen, Jia Ying Lu, Hong Qi Li, Yu Xiang Yang, Jie Hui Jiang, Mei Cui, Chuan Tao Zuo, Lan Tan, Qiang Dong, Jin Tai Yu, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Richard J. Perrin, Leslie M. Shaw, Maria Carrillo, William Potter, Lisa Barnes, Marie Bernard, Hector González, Carole Ho, John K. Hsiao, Jonathan Jackson, Eliezer Masliah, Donna Masterman, Ozioma Okonkwo
Clinical Research Faculty Publications
A biological research framework to define Alzheimer’ disease with dichotomized biomarker measurement was proposed by National Institute on Aging–Alzheimer’s Association (NIA–AA). However, it cannot characterize the hierarchy spreading pattern of tau pathology. To reflect in vivo tau progression using biomarker, we constructed a refined topographic 18F-AV-1451 tau PET staging scheme with longitudinal clinical validation. Seven hundred and thirty-four participants with baseline 18F-AV-1451 tau PET (baseline age 73.9 ± 7.7 years, 375 female) were stratified into five stages by a topographic PET staging scheme. Cognitive trajectories and clinical progression were compared across stages with or without further dichotomy of amyloid status, …
Experimental Investigation Of The Aerodynamics Of A Large Industrial Building With Parapet, Aly Mousaad Aly, Matthew Thomas, Hamzeh Gol-Zaroudi
Experimental Investigation Of The Aerodynamics Of A Large Industrial Building With Parapet, Aly Mousaad Aly, Matthew Thomas, Hamzeh Gol-Zaroudi
Faculty Publications
The aerodynamic performance of a roof depends significantly on its shape and size, among other factors. For instance, large roofs of industrial low-rise buildings may behave differently compared to those of residential homes. The main objective of this study is to experimentally investigate how perimeter solid parapets can alter the flow pattern around a low-rise building with a large aspect ratio of width/height of about 7.6, the case of industrial buildings/shopping centers. Solid parapets of varied sizes are added to the roof and tested in an open-jet simulator in a comparative study to understand their impact on roof pressure coefficients. …
Expanding The Concept Of Comprehensive Area Ratio Parameter To The South-Central States: Towards Simplifying The Structural Evaluation Of Flexible Pavements At The Network Level, Mena Souliman, Samer Dessouky, Nitish R. Bastola
Expanding The Concept Of Comprehensive Area Ratio Parameter To The South-Central States: Towards Simplifying The Structural Evaluation Of Flexible Pavements At The Network Level, Mena Souliman, Samer Dessouky, Nitish R. Bastola
Publications
The surface deflection bowl data collected through falling weight deflectometer (FWD) test is utilized by highway agencies in assessing the performance of the flexible pavement. However, a robust method to evaluate pavement sections utilizing FWD data from all the sensors is seldom developed. There is always a need for DOTs and highway agencies to have a simplified procedure, which can be directly implemented in agencies' databases. This study focuses on expanding and validating the concept of previously developed area ratio parameters towards the pavement section of South-Central States (Arkansas, Louisiana, New Mexico, Oklahoma, and Texas) in effectively analyzing the pavement …
Ncs Assessments Of The Motor, Sensory, And Physical Health Domains, Jane E. Clark, Russell Pate, Rose Marie Rine, Jennifer Christy, Pamela Dalton, Diane L. Damiano, Stephen Daniels, Jonathan M. Holmes, Peter T. Katzmarzyk, Susan Magasi, Ryan Mccreery, Kerry Mciver, Karl M. Newell, Terence Sanger, David Sugden, Elsie Taveras, Steven Hirschfeld
Ncs Assessments Of The Motor, Sensory, And Physical Health Domains, Jane E. Clark, Russell Pate, Rose Marie Rine, Jennifer Christy, Pamela Dalton, Diane L. Damiano, Stephen Daniels, Jonathan M. Holmes, Peter T. Katzmarzyk, Susan Magasi, Ryan Mccreery, Kerry Mciver, Karl M. Newell, Terence Sanger, David Sugden, Elsie Taveras, Steven Hirschfeld
Population and Public Health Science Faculty Publications
As part of the National Children's Study (NCS) comprehensive and longitudinal assessment of the health status of the whole child, scientific teams were convened to recommend assessment measures for the NCS. This manuscript documents the work of three scientific teams who focused on the motor, sensory, or the physical health aspects of this assessment. Each domain team offered a value proposition for the importance of their domain to the health outcomes of the developing infant and child. Constructs within each domain were identified and measures of these constructs proposed. Where available extant assessments were identified. Those constructs that were in …
The Use Of Rna Interference To Investigate The Role Of Zmpr10 In Salt Stress Response And Mtl/Nld/Zmpla1 In The Improvement Of Haploid Induction In Maize, Max Carl Miller
The Use Of Rna Interference To Investigate The Role Of Zmpr10 In Salt Stress Response And Mtl/Nld/Zmpla1 In The Improvement Of Haploid Induction In Maize, Max Carl Miller
LSU Master's Theses
RNA interference (RNAi) is a useful tool in gene characterization and its use is expanding into more practical fields. Two RNAi techniques were used in this case. The studies conducted in the chapter two use transgenic maize lines containing an RNAi construct targeting ZmPR10 to characterize its potential role in growth and development in response to salinity stress. T1 transgenic plants from events A44S1-35-3 and A44S1-3-4, which had significantly reduced ZmPR10 expression compared to the non-transgenic controls, showed no differences compared to the controls in heights after 30 and 60 days, nor did the T2 transgenic from these …
Parallel Coordinates-Based Visualization Of Covid-19 Data, Puja Bhandari
Parallel Coordinates-Based Visualization Of Covid-19 Data, Puja Bhandari
LSU Master's Theses
The number of COVID-19 cases has been continuously increasing worldwide since the beginning of 2020. A lot of efforts have been made in identifying, predicting, and mitigating this deadly virus infection. This requires gaining insight into large collections of the related data, which are multivariate in nature involving many variables/attributes. Here we develop a parallel coordinates system to visualize the COVID-19 data in an interactive manner considering all variables, including location and time. The challenges with this approach include mapping many variables of different types (parallel axes) and occlusion associated with highly cluttered data lines. We adopt several functionalities to …
Cfd Simulations Of Macroscopic And Microscopic Multiphase Fluid Flow And Droplet Interaction, Aaron Harrington
Cfd Simulations Of Macroscopic And Microscopic Multiphase Fluid Flow And Droplet Interaction, Aaron Harrington
LSU Master's Theses
Multiphase flow is a complex phenomenon which can be modeled on numerous different length scales, both macroscopically and microscopically. The use of a Euler-Euler model for Computation Fluid Dynamics (CFD) simulations of subcooled boiling phenomena is discussed in detail. The CFD conditions have been set up to mimic previous experimental conditions. A cylindrical vessel with subcooled liquid flow is heated along part of the axial wall of the vessel. A constant heat flux is applied to produce subcooled boiling. We discuss the development of the phase change within the vessel as well as the temperature profile, and validate the results …
Crystallization-Driven Self-Assembly Of Coil-Comb Shaped Polypeptoid Block Copolymers: Controlling The Growth Of One-Dimensional Nanostructures, Md Asmat Ullah
Crystallization-Driven Self-Assembly Of Coil-Comb Shaped Polypeptoid Block Copolymers: Controlling The Growth Of One-Dimensional Nanostructures, Md Asmat Ullah
LSU Master's Theses
Poly-peptoid based nanoparticles have gained much attention concerning applications in biotechnology or biomedicine due to their biocompatibility and biodegradability. However, the controlled growth of colloidally stable polypeptoid nanostructures of uniform size and controlled geometry remains a major challenge. In this study, the crystallization driven self-assembly (CDSA) of amphiphilic polypeptoid diblock co-polymers, namely poly (N-methyl glycine)-b-poly (N-decyl glycine) (PNMG-b-PNDG), was investigated for the growth of one-dimensional (1D) nanostructures in solution. PNMG-b-PNDG block copolymers (M98D20) were synthesized by sequential benzyl amine-initiated ring-opening polymerizations of the corresponding N-substituted glycine derived N-carboxy anhydrides, in which the degree of …
Evaluating Consumers’ Perception Of Gluten-Free/Clean-Label Muffins, Vanesa Chicaiza
Evaluating Consumers’ Perception Of Gluten-Free/Clean-Label Muffins, Vanesa Chicaiza
LSU Master's Theses
The gluten-free-natural-ingredient (GF/NCL) product demand is globally increasing and driven by the growing prevalence of celiac-diseases. Nevertheless, the quality of GF product is often inferior compared to wheat-flour counterparts due to the removing of gluten, which, compromises the appearance, structure, and nutritional value. The addition of fiber into GF/NCL products has been considered to improve nutritional values while maintaining quality attributes. According to the US-FDA, a product containing ≥2.5 grams of fiber/serving can be claimed as a “good-source-of-fiber.” However, adding dietary fiber to baked products affects their qualities, and hence possibly lowering product acceptability.
The main objective of this research …
Examining The Effectiveness Of “Turn Around Don’T Drown”, Chance D. Bryant
Examining The Effectiveness Of “Turn Around Don’T Drown”, Chance D. Bryant
LSU Master's Theses
Extreme heat is the deadliest weather hazard in the U.S. Flooding is the second worst, and flash flooding is the deadliest form of flooding. The nature of these flood deaths contains a human element that deserves greater study. Since 2004, the National Weather Service has attempted to educate the public with its slogan, ``Turn Around Don’t Drown". Vehicle related mortality rates in Texas since 1996 were examined to answer the question of whether ``Turn Around Don’t Drown" has been effective. The slogan has a large footprint on the social media platform Twitter, with most of the Tweets coming from private …