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Initial Epidemic Area Is Strongly Associated With The Yearly Extent Of Soybean Rust Spread In North America, Christopher C. Mundt, La Rae D. Wallace, Tom W. Allen, Clayton A. Hollier, Robert C. Kemerait, Edward J. Sikora Jul 2013

Initial Epidemic Area Is Strongly Associated With The Yearly Extent Of Soybean Rust Spread In North America, Christopher C. Mundt, La Rae D. Wallace, Tom W. Allen, Clayton A. Hollier, Robert C. Kemerait, Edward J. Sikora

Faculty Publications

Hosts of soybean rust (Phakopsora pachyrhizi) are sensitive to low temperatures, limiting this obligate parasite in the United States to overwintering sites in a restricted area along the Gulf Coast. This temperature sensitivity of soybean rust hosts allowed us to study spatial spread of epidemic invasions over similar territory for seven sequential years, 2005-2011. The epidemic front expanded slowly from early April through July, with the majority of expansion occurring from August through November. There was a 7.4-fold range of final epidemic extent (0.4-3.0 million km2) from the year of smallest final disease extent (2011) to that of the largest …

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Il-4rα On Cd4+ T Cells Plays A Pathogenic Role In Respiratory Syncytial Virus Reinfection In Mice Infected Initially As Neonates, Dahui You, Nico Marr, Jordy Saravia, Bishwas Shrestha, Greg I. Lee, Stuart E. Turvey, Frank Brombacher, De'broski R. Herbert, Stephania A. Cormier Jun 2013

Il-4rα On Cd4+ T Cells Plays A Pathogenic Role In Respiratory Syncytial Virus Reinfection In Mice Infected Initially As Neonates, Dahui You, Nico Marr, Jordy Saravia, Bishwas Shrestha, Greg I. Lee, Stuart E. Turvey, Frank Brombacher, De'broski R. Herbert, Stephania A. Cormier

Faculty Publications

RSV is the major cause of severe bronchiolitis in infants, and severe bronchiolitis as a result of RSV is associated with subsequent asthma development. A biased Th2 immune response is thought to be responsible for neonatal RSV pathogenesis; however, molecular mechanisms remain elusive. Our data demonstrate, for the first time, that IL-4Rα is up-regulated in vitro on human CD4+ T cells from cord blood following RSV stimulation and in vivo on mouse pulmonary CD4+ T cells upon reinfection of mice, initially infected as neonates. Th cell-specific deletion of Il4ra attenuated Th2 responses and abolished the immunopathophysiology upon reinfection, including airway …

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Developing Models Of Disease Transmission: Insights From Ecological Studies Of Insects And Their Baculoviruses, Bret D. Elderd Jun 2013

Developing Models Of Disease Transmission: Insights From Ecological Studies Of Insects And Their Baculoviruses, Bret D. Elderd

Faculty Publications

No abstract provided.

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Dissemination Of Bloodmeal Acquired Rickettsia Felis In Cat Fleas, Ctenocephalides Felis, Chutima Thepparit, Supanee Hirunkanokpun, Vsevolod L. Popov, Lane D. Foil, Kevin R. Macaluso May 2013

Dissemination Of Bloodmeal Acquired Rickettsia Felis In Cat Fleas, Ctenocephalides Felis, Chutima Thepparit, Supanee Hirunkanokpun, Vsevolod L. Popov, Lane D. Foil, Kevin R. Macaluso

Faculty Publications

Background: Cat fleas, Ctenocephalides felis, are known biological vectors for Rickettsia felis. Rickettsial transmission can be vertical via transovarial transmission within a flea population, as well as horizontal between fleas through a bloodmeal. The previously undescribed infection kinetics of bloodmeal-acquired R. felis in cat fleas provides insight into the R. felis-flea interaction. Findings. In the present study, dissemination of R. felis in previously uninfected cat fleas fed an R. felis-infected bloodmeal was investigated. At weekly intervals for 28 days, rickettsial propagation, accumulation, and dissemination in gut epithelial cells, specifically in the hindgut and the specialized cells in the neck region …

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The Urban Health Transition Hypothesis: Empirical Evidence Of An Avian Influenza Kuznets Curve In Vietnam?, James Herbert Spencer Apr 2013

The Urban Health Transition Hypothesis: Empirical Evidence Of An Avian Influenza Kuznets Curve In Vietnam?, James Herbert Spencer

Faculty Publications

The literature on development has focused on the concept of transition in understanding the emergent challenges facing poor but rapidly developing countries. Scholars have focused extensively on the health and urban transitions associated with this change and, in particular, its use for understanding emerging infectious diseases. However, few have developed explicit empirical measures to quantify the extent to which a transitions focus is useful for theory, policy, and practice. Using open source data on avian influenza in 2004 and 2005 and the Vietnam Census of Population and Housing, this paper introduces the Kuznets curve as a tool for empirically estimating …

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Analyzing The Population Structure Of Captive Marmosets Using Alu Retrotransposons, Megan Ranck Apr 2013

Analyzing The Population Structure Of Captive Marmosets Using Alu Retrotransposons, Megan Ranck

Honors Capstones

No abstract provided.

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Effects Of Biogents Sentinel Trap Field Placement On Capture Rates Of Adult Asian Tiger Mosquitoes, Aedes Albopictus, Taryn N. Crepeau, Sean P. Healy, Kristen Bartlett-Healy, Isik Unlu, Ary Farajollahi, Dina M. Fonseca Mar 2013

Effects Of Biogents Sentinel Trap Field Placement On Capture Rates Of Adult Asian Tiger Mosquitoes, Aedes Albopictus, Taryn N. Crepeau, Sean P. Healy, Kristen Bartlett-Healy, Isik Unlu, Ary Farajollahi, Dina M. Fonseca

Faculty Publications

The Biogents® Sentinel (BGS) trap is the standard tool to monitor adult Aedes (Stegomyia) albopictus (Skuse) (Diptera: Culicidae), the Asian tiger mosquito. BGS traps are commonly placed in residential properties during surveillance operations, but locations within properties may have significant differences in ambient light, temperature, and humidity (e.g. between a sunlit lawn and shady underbrush). We examined the effect of BGS trap placement on Ae. albopictus capture rates in three residential properties in Monmouth County, New Jersey, USA. In each property we visually selected locations as shade, partial shade, and sun. Traps in "partial shade" locations were under vegetation and …

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Vitronectin Inhibits Efferocytosis Through Interactions With Apoptotic Cells As Well As With Macrophages, Hong Beom Bae, Jean Marc Tadie, Shaoning Jiang, Dae Won Park, Celeste P. Bell, Lawrence C. Thompson, Cynthia B. Peterson, Victor J. Thannickal, Edward Abraham, Jaroslaw W. Zmijewski Mar 2013

Vitronectin Inhibits Efferocytosis Through Interactions With Apoptotic Cells As Well As With Macrophages, Hong Beom Bae, Jean Marc Tadie, Shaoning Jiang, Dae Won Park, Celeste P. Bell, Lawrence C. Thompson, Cynthia B. Peterson, Victor J. Thannickal, Edward Abraham, Jaroslaw W. Zmijewski

Faculty Publications

Effective removal of apoptotic cells, particularly apoptotic neutrophils, is essential for the successful resolution of acute inflammatory conditions. In these experiments, we found that whereas interaction between vitronectin and integrins diminished the ability of macrophages to ingest apoptotic cells, interaction between vitronectin with urokinase-type plasminogen activator receptor (uPAR) on the surface of apoptotic cells also had equally important inhibitory effects on efferocytosis. Preincubation of vitronectin with plasminogen activator inhibitor-1 eliminated its ability to inhibit phagocytosis of apoptotic cells. Similarly, incubation of apoptotic cells with soluble uPAR or Abs to uPAR significantly diminished efferocytosis. In the setting of LPSinduced ALI, enhanced …

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The Kaposi's Sarcoma-Associated Herpesvirus Orf34 Protein Binds To Hif-1Α And Causes Its Degradation Via The Proteasome Pathway, Muzammel Haque, Konstantin G. Kousoulas Feb 2013

The Kaposi's Sarcoma-Associated Herpesvirus Orf34 Protein Binds To Hif-1Α And Causes Its Degradation Via The Proteasome Pathway, Muzammel Haque, Konstantin G. Kousoulas

Faculty Publications

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi's sarcoma (KS) and two other lymphoproliferative disorders, primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). Kaposi's sarcoma is a highly vascular tumor, and recently both hypoxia-inducible factor 1α (HIF-1α) and HIF-2α were detected in KS samples, indicating a role of HIFs in the KSHV life cycle. Previously, we showed that ORF34, a lytic gene of unassigned function, was activated by hypoxia and that ORF34 transcription was upregulated by both HIFs (M. Haque, D. A. Davis, V. Wang, I. Widmer, and R. Yarchoan, J Virol. 77:6761- 6768, 2003). In the …

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Physiological Effects Of Tourism And Associated Food Provisioning In An Endangered Iguana, Charles R. Knapp, Kirsten N. Hines, Trevor T. Zachariah, Caro Perez-Heydrich, John B. Iverson, Sandra D. Buckner, Shelley C. Halach, Christine R. Lattin, L. Michael Romero Jan 2013

Physiological Effects Of Tourism And Associated Food Provisioning In An Endangered Iguana, Charles R. Knapp, Kirsten N. Hines, Trevor T. Zachariah, Caro Perez-Heydrich, John B. Iverson, Sandra D. Buckner, Shelley C. Halach, Christine R. Lattin, L. Michael Romero

Faculty Publications

© The Author 2013. Deliberately feeding wildlife is an increasingly popular tourism-related activity despite a limited understanding of long-term impacts on the species being fed. As a result, tourist behaviours that may have adverse impacts on imperiled species have often been encouraged without the necessary evaluation or oversight. Here, we report the responses of Northern Bahamian Rock Iguanas (Cyclura cychlura) to human-visitation pressure and associated food provisioning. We compared a variety of blood chemistry parameters of iguanas subjected to supplemental feeding at popular tourist destinations with iguanas occurring on islands where supplemental feeding does not take place. We demonstrate that …

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Intracellular Glucocorticoid Receptors Inspleen, But Not Skin, Vary Seasonally Inwild House Sparrows (Passer Domesticus), Christine R. Lattin, K. Waldron-Francis, L. Michael Romero Jan 2013

Intracellular Glucocorticoid Receptors Inspleen, But Not Skin, Vary Seasonally Inwild House Sparrows (Passer Domesticus), Christine R. Lattin, K. Waldron-Francis, L. Michael Romero

Faculty Publications

Over the short-term and at physiological doses, acute increases in corticosterone (CORT) titres can enhance immune function. There are predictable seasonal patterns in both circulating CORT and immune function across many animal species, but whether CORT receptor density in immune tissues varies seasonally is currently unknown. Using radioligand binding assays, we examined changes in concentrations of glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) in spleen and skin in wild-caught house sparrows in Massachusetts during six different life-history stages: moult, early winter, late winter, pre-egg-laying, breeding and late breeding. Splenic GR and MR binding were highest during the pre-laying period. This …

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Particulate Matter Containing Environmentally Persistent Free Radicals And Adverse Infant Respiratory Health Effects: A Review, Jordy Saravia, Greg I. Lee, Slawo Lomnicki, Barry Dellinger, Stephania A. Cormier Jan 2013

Particulate Matter Containing Environmentally Persistent Free Radicals And Adverse Infant Respiratory Health Effects: A Review, Jordy Saravia, Greg I. Lee, Slawo Lomnicki, Barry Dellinger, Stephania A. Cormier

Faculty Publications

The health impacts of airborne particulate matter (PM) are of global concern, and the direct implications to the development/exacerbation of lung disease are immediately obvious. Most studies to date have sought to understand mechanisms associated with PM exposure in adults/adult animal models; however, infants are also at significant risk for exposure. Infants are affected differently than adults due to drastic immaturities, both physiologically and immunologically, and it is becoming apparent that they represent a critically understudied population. Highlighting our work funded by the ONES award, in this review we argue the understated importance of utilizing infant models to truly understand …

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Synthesis, Characterization And Biological Studies Of Carboranyl-Porphyrin Bioconjugates For Treatment Of Brain Tumors, Naga Venkata Satya Dinesh Kumar Bhupathiraju Jan 2013

Synthesis, Characterization And Biological Studies Of Carboranyl-Porphyrin Bioconjugates For Treatment Of Brain Tumors, Naga Venkata Satya Dinesh Kumar Bhupathiraju

LSU Doctoral Dissertations

Chapter 1 gives a brief introduction to brain tumors, approaches to deliver drug across the blood brain barrier (BBB), boron neutron capture therapy (BNCT) for brain tumors, application of carboranyl derivatives in attempt to treat brain tumors using BNCT. Chapter 2 involves synthesis, characterization and toxicity studies (In vitro and In vivo) of high boron containing pegylated cobaltabisdicarbollide porphyrin for treatment of brain tumors using BNCT. To improve the selectivity towards brain tumors we attempted conjugate several peptides to this non-toxic pegylated cobaltabiscabollide porphyrin. In vivo studies were conducted in collaboration with Dr. David G. Baker at LSU veterinary Medicine. …

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Development Of Safe And Ready To Eat Frozen Oyster Products Using Microwave Steam-Venting Technology, Luis Alberto Espinoza Jan 2013

Development Of Safe And Ready To Eat Frozen Oyster Products Using Microwave Steam-Venting Technology, Luis Alberto Espinoza

LSU Doctoral Dissertations

The Gulf Coast region, principally Louisiana, leads the nation in oyster production. The National Marine Fisheries Service reported that 19.7 million pounds of oyster meat, valued at $62.3 million dollars were harvested from the Gulf Coast region in 2010. One of the main concerns for this industry is the health risk associated with the consumption of oysters, particularly for at-risk populations. Oysters are filter feeders. They tend to concentrate microbes present in surrounding waters, some of which can cause severe illness in susceptible humans. Among pathogens that contaminate the gastrointestinal system of oysters, Vibrio spp (especially V. parahaemolyticus and V. …

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Vibrio Parahaemolyticus Interactions With Chitin In Response To Environmental Factors, Vanessa Molina Jan 2013

Vibrio Parahaemolyticus Interactions With Chitin In Response To Environmental Factors, Vanessa Molina

LSU Doctoral Dissertations

Vibrio parahaemolyticus is a naturally occurring chitinoclastic human pathogen that adsorbs to substrates, including chitinous copepods and oysters, as part of its ecology, a phenomenon that is important in its responses to changes in environmental factors such as temperature and salinity. Little is known about acute responses of V. parahaemolyticus when subjected to abrupt environmental changes such as those encountered during postharvest oyster treatments such as icing, exposure to mammalian host conditions, and transport via ballast water. The following in vitro studies investigated V. parahaemolyticus adsorption and gene expression as a function of substrate, temperature, and salinity as a model …

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Investigation Of Best Practices For Maintenance Of Concrete Bridge Railings, Angel Luis Lence Jan 2013

Investigation Of Best Practices For Maintenance Of Concrete Bridge Railings, Angel Luis Lence

LSU Master's Theses

Biodeterioration on concrete surfaces of vertical elements of bridges represents a serious challenge to the highway infrastructure in Louisiana. This investigation aims to document the causes of biodeterioration of concrete surfaces and to document current conventional and state-of-the-art practices implemented to prevent and clean biofilm. A comprehensive literature review of previous research has been carried out in order to determine the cause and mechanisms of the biodeterioration as well as to identify current methods that state DOTs have implemented in order to maintain their bridges and allow them to function in optimal structural and performance conditions. A survey was developed …

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Power And Purpose : U.S. Foreign Aid And Development, Jeremy L. Wells Jan 2013

Power And Purpose : U.S. Foreign Aid And Development, Jeremy L. Wells

LSU Doctoral Dissertations

Foreign aid represents about 1 percent of the United States federal budget, but it also represents a significant portion of many recipient countries’ gross domestic products. Although there has been substantial interest in foreign aid among international political economy researchers over the last decade or so, there are still few if any answers to the most basic questions: who gets foreign aid, how much, and is it effective? Through a combination of cross-national analyses and a quantitative case study of Afghanistan during the Taliban insurgency of 2003–2009, this dissertation seeks to advance our understanding of the utility of foreign aid …

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Yogurt Cultured Milk Powder As A Substitute For Yogurt Powder, Lijie Song Jan 2013

Yogurt Cultured Milk Powder As A Substitute For Yogurt Powder, Lijie Song

LSU Master's Theses

Commercial yogurt powder has to go through drying process which kills the yogurt culture, so the health benefit of the yogurt culture bacteria are lost. Also, upon reconstitution commercial yogurt powder does not taste like yogurt, it is sour and off flavored. The hypothesis of this study was that yogurt cultured milk powder would have better culture bacterial counts, better physico-chemical and sensory characteristics than commercial yogurt powder currently available. Commercial yogurt powder (CYP) was the control and yogurt cultured milk powder (YCMP) was the treatment. Freeze-dried yogurt starter culture (Lactobacillus bulgaricus and Streptococcus thermophilus at ratio 1:1) was added …

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Fabrication And Characterization Of A Polymeric Nanofluidic Device For Dna Analysis, Jiahao Wu Jan 2013

Fabrication And Characterization Of A Polymeric Nanofluidic Device For Dna Analysis, Jiahao Wu

LSU Doctoral Dissertations

The growing needs for cheaper and faster sequencing of long biopolymers such as DNA and RNA have prompted the development of new technologies. Among the novel techniques for analyzing these biopolymers, an approach using nanochannel based fluidic devices is attractive because it is a label-free, amplification-free, single-molecule method that can be scaled for high-throughput analysis. Despite recent demonstrations of nanochannel based fluidic devices for analyzing physical properties of such biopolymers, most of the devices have been fabricated in inorganic materials such as silicon, silicon nitride and glass using expensive high end nanofabrication techniques such as focused ion beam and electron …

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Controversy Trend Detection In Social Media, Rajshekhar Vishwanath Chimmalgi Jan 2013

Controversy Trend Detection In Social Media, Rajshekhar Vishwanath Chimmalgi

LSU Master's Theses

In this research, we focus on the early prediction of whether topics are likely to generate significant controversy (in the form of social media such as comments, blogs, etc.). Controversy trend detection is important to companies, governments, national security agencies, and marketing groups because it can be used to identify which issues the public is having problems with and develop strategies to remedy them. For example, companies can monitor their press release to find out how the public is reacting and to decide if any additional public relations action is required, social media moderators can moderate discussions if the discussions …

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Concentration And Detection Of Hepatitis A Virus And Its Indicator From Seawater, Jiemin Cormier Jan 2013

Concentration And Detection Of Hepatitis A Virus And Its Indicator From Seawater, Jiemin Cormier

LSU Doctoral Dissertations

Hepatitis A virus (HAV) infection is the leading worldwide cause of acute viral hepatitis, and its outbreaks often occur from fecal contaminated shellfish. HAV is extremely stable in the environment and can survive 3~10 months in water. In addition, HAV can be bio-concentrated by shellfish by as much as 100 fold from fecal contaminated waters. Bacteriophage MS2 is used widely as a surrogate for HAV, and its presence has been proven to be a reliable indication of the presence of HAV. A rapid detection of viral contamination in water environments can prevent economic loss and can identify the source of …

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Mathematical And Computer-Based Models For Optimizing Microwave Heating Processes Of Frozen Oysters, Jie Zhang Jan 2013

Mathematical And Computer-Based Models For Optimizing Microwave Heating Processes Of Frozen Oysters, Jie Zhang

LSU Doctoral Dissertations

Consumers with full-time jobs prefer microwavable-frozen-meals for convenience when lack time to cook. Microwaves do not require a medium for heat transfer and provide quick heating even in low thermal conductivity foods, which does not occur in conventional heating. The main problem in utilizing microwave-heating for cooking is the non-uniform temperature distribution in foods which may result in insufficient lethality of microorganisms in some part. This non-uniformity can be due to a number of factors including composition and geometry of food. The objectives of this study were to develop a mathematical-model based on Maxwell¡¯s equations for predicting the temperature distribution …

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Role Of Nod2/Rip2 Signaling In Acute Bacterial Pneumonia And Sepsis, Balamayooran Theivanthiran Jan 2013

Role Of Nod2/Rip2 Signaling In Acute Bacterial Pneumonia And Sepsis, Balamayooran Theivanthiran

LSU Doctoral Dissertations

Bacterial pneumonia and sepsis are two important causes of mortality in the world. Emergence of multidrug resistant bacteria has necessitated the development of new treatment and/or prevention strategies to augment host immune defense. In this context, the innate host defense is critical in clearing pathogenic bacteria from the host. Early neutrophil recruitment is a critical step in a multistep requence leading to bacterial clearance. Pattern recognition receptors (PRRs) play a critical role in the innate immune system. Receptor interacting protein 2 (RIP-2) is an adaptor for the nod-like receptors (NLR) NOD1 and NOD2. Nucleotide oligomerisation domain 2 (NOD2) is an …

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Treatments To Reduce The Risk Of Vibrio Species In Vitro And In Shucked Oysters, Ronson Renard Scott Jan 2013

Treatments To Reduce The Risk Of Vibrio Species In Vitro And In Shucked Oysters, Ronson Renard Scott

LSU Master's Theses

"Vibrio parahaemolyticus" (Vp) and "Vibrio vulnificus" (Vv) are halophilic bacteria naturally occurring in estuarine environments that may concentrate in filter feeding shellfish. Consumption of raw or under-cooked seafood contaminated with Vp or Vv may lead to the development of acute gastroenteritis or fatal septicemia in at-risk individuals, respectively. This research encompassed two separate but related projects: evaluation of a low temperature pasteurization (LTP) technique for the reduction of Vp and Vv in commercial quantities of shucked oysters (SO) and the investigation of the efficacy of a citrus fruit extract, BIOSECUR® F440D in reducing/eliminating Vv in vitro. Commercially available SO ("Crassostrea …

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Modeling The Influence Of Peromyscus Leucopus Body Mass, Sex, And Habitat On Immature Dermacentor Variabilis Burden, Tad A. Dallas, Stephanie A. Foré, Hyun Joo Kim Dec 2012

Modeling The Influence Of Peromyscus Leucopus Body Mass, Sex, And Habitat On Immature Dermacentor Variabilis Burden, Tad A. Dallas, Stephanie A. Foré, Hyun Joo Kim

Faculty Publications

mmature (larvae and nymph) tick burden on rodents is an important determinant of adult tick population size and understanding infectious disease dynamics. The objective of this research was to build a descriptive model for immature Dermacentor variabilis burden on Peromyscus leucopus. Mice were live-trapped on two permanent grids in an old field and an early successional forest every other month between April and October, 2006-2009. Negative binomial regression was used to examine the association between immature D. variabilis burden and the host related variables of host habitat, body mass, and/or sex. The model containing all three variables had the lowest …

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Hsv-1 Latent Rabbits Shed Viral Dna Into Their Saliva, James M. Hill, Nicole M. Nolan, Harris E. Mcferrin, Christian Clement, Timothy P. Foster, William P. Halford, Konstantin G. Kousoulas, Walter J. Lukiw, Hilary W. Thompson, Ethan M. Stern, Partha S. Bhattacharjee Oct 2012

Hsv-1 Latent Rabbits Shed Viral Dna Into Their Saliva, James M. Hill, Nicole M. Nolan, Harris E. Mcferrin, Christian Clement, Timothy P. Foster, William P. Halford, Konstantin G. Kousoulas, Walter J. Lukiw, Hilary W. Thompson, Ethan M. Stern, Partha S. Bhattacharjee

Faculty Publications

Background: Rabbits latent with HSV-1 strain McKrae spontaneously shed infectious virus and viral DNA into their tears and develop recurrent herpetic-specific corneal lesions. The rabbit eye model has been used for many years to assess acute ocular infections and pathogenesis, antiviral efficacy, as well as latency, reactivation, and recurrent eye diseases. This study used real-time PCR to quantify HSV-1 DNA in the saliva and tears of rabbits latent with HSV-1 McKrae. Methods. New Zealand white rabbits used were latent with HSV-1 strain McKrae and had no ocular or oral pathology. Scarified corneas were topically inoculated with HSV-1. Eye swabs and …

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Analysis Of Drug Resistance Determinants In Klebsiella Pneumoniae Isolates From A Tertiary-Care Hospital In Beijing, China, Bin Li, Yong Yi, Qi Wang, Patrick C.Y. Woo, Lin Tan, Hua Jing, George F. Gao, Cui Hua Liu Jul 2012

Analysis Of Drug Resistance Determinants In Klebsiella Pneumoniae Isolates From A Tertiary-Care Hospital In Beijing, China, Bin Li, Yong Yi, Qi Wang, Patrick C.Y. Woo, Lin Tan, Hua Jing, George F. Gao, Cui Hua Liu

Faculty Publications

Background: The rates of multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) isolates among Enterobacteriaceae isolates, particularly Klebsiella pneumoniae, have risen substantially worldwide. Methodology/Principal Findings: To better understand the molecular mechanisms of drug resistance in K. pneumoniae, we analyzed the drug resistance determinants for K. pneumoniae isolates collected from the 306 Hospital, a tertiary-care hospital in Beijing, China, for the period of September 1, 2010-October 31, 2011. Drug susceptibility testing, PCR amplification and sequencing of the drug resistance determinants were performed. Conjugation experiments were conducted to examine the natural ability of drug resistance to disseminate among Enterobacteriaceae strains using a …

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An Actor-Based Model Of Social Network Influence On Adolescent Body Size, Screen Time, And Playing Sports, David A. Shoham, Liping Tong, Peter J. Lamberson, Amy H. Auchincloss, Jun Zhang, Lara Dugas, Jay S. Kaufman, Richard S. Cooper, Amy Luke Jun 2012

An Actor-Based Model Of Social Network Influence On Adolescent Body Size, Screen Time, And Playing Sports, David A. Shoham, Liping Tong, Peter J. Lamberson, Amy H. Auchincloss, Jun Zhang, Lara Dugas, Jay S. Kaufman, Richard S. Cooper, Amy Luke

Faculty Publications

Recent studies suggest that obesity may be "contagious" between individuals in social networks. Social contagion (influence), however, may not be identifiable using traditional statistical approaches because they cannot distinguish contagion from homophily (the propensity for individuals to select friends who are similar to themselves) or from shared environmental influences. In this paper, we apply the stochastic actor-based model (SABM) framework developed by Snijders and colleagues to data on adolescent body mass index (BMI), screen time, and playing active sports. Our primary hypothesis was that social influences on adolescent body size and related behaviors are independent of friend selection. Employing the …

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A Content Analysis Into The Social Development Campaigns Of The Fédération Internationale De Football Association (Fifa), Tyler Henry Apr 2012

A Content Analysis Into The Social Development Campaigns Of The Fédération Internationale De Football Association (Fifa), Tyler Henry

Honors Capstones

No abstract provided.

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Amending The Stafford Act: Considerations For A Catastrophic Declaration, Ernest Brian Baudoin Apr 2012

Amending The Stafford Act: Considerations For A Catastrophic Declaration, Ernest Brian Baudoin

Honors Capstones

No abstract provided.

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