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Size Effects In Additively Manufactured Inconel-718 Thin Elements And Cellular Structures, Reem Abdelkarim Abo Znemah Jul 2023

Size Effects In Additively Manufactured Inconel-718 Thin Elements And Cellular Structures, Reem Abdelkarim Abo Znemah

LSU Doctoral Dissertations

A current focus in the additive manufacturing (AM) research community is the production of complex shaped metallic parts and cellular structures. Many researchers went on analyzing and simulating these structures without considering the effect of the element thickness and heterogeneous printing parameters on the resulting material behavior. To advance the application of laser powder bed fusion (LPBF), an AM process, in producing Inconel718 (IN718) complex shaped parts and cellular structures, this study aimed to investigate the effect of thin-walled elements thickness on the mechanical characteristics of both the individual elements and overall cellular structure. A multiscale experimental evaluation of the …


Cultural Expression And Relevancy Communicated Through Marching Band Performance In Louisiana, Nicholas Ashton Jul 2023

Cultural Expression And Relevancy Communicated Through Marching Band Performance In Louisiana, Nicholas Ashton

LSU Master's Theses

This study explored the use of marching band membership as a medium of mass communication through in-depth interviews with Louisiana collegiate marching band participants and subsequent analysis. Since these groups tend to serve as their school’s face and brand ambassadors in many cases, this study will look to their constituent members to explore what it is truly like to be a small cog that makes the whole run effectively and efficiently. Intersections of a marching band’s outward-facing image and its members’ personally held values, beliefs, and preferences are of specific interest in an effort to understand the effects of mass …


Women's Interracial Friendships: Cultivating Coalitional Possibilities Across Difference Through Dialogue, Akie Fukushige Wenk Jul 2023

Women's Interracial Friendships: Cultivating Coalitional Possibilities Across Difference Through Dialogue, Akie Fukushige Wenk

LSU Doctoral Dissertations

In my dissertation, I thread through the macro-structure as well as micro-operations of hegemonic ideologies, namely white-supremacist capitalist cis-hetero patriarchy (hooks, 1995, Valdes, 1996), that has historically plagued the United States, eventually gaining a global reach over time. I center interracial friendship between Black and White cis-women, where I locate coalitional possibilities that begin at the grassroots level. I situate this interracial relationship within the socio-ecological system where the personal meets the social (including racialized backgrounds). I use a series of analogies to equate these ideologies as toxins in the air, water, and soil. Soil is where we can work …


The Case For Succession Planning In Higher Education: A Study Of Knowledge Transfer Within Louisiana State University, Leila Shaik Villien Jul 2023

The Case For Succession Planning In Higher Education: A Study Of Knowledge Transfer Within Louisiana State University, Leila Shaik Villien

LSU Doctoral Dissertations

The primary purpose of this study was to explore the challenges, benefits, and perceptions of succession planning among currently employed administrators at research universities in the southern portion of the United States at the level of assistant department head or higher and the accessible population was defined as currently employed administrators at Louisiana State University at the level of assistant department head or higher. Deans, Associate Deans, Department Heads, Assistant Department Heads, and Department Chairs were invited to participate in an online survey designed by the researcher to assess the attitude toward succession planning and training, along with a variety …


Morphological And Molecular Characterization Of The Olfactory System In The Formosan Subterranean Termite, Paula Castillo Jul 2023

Morphological And Molecular Characterization Of The Olfactory System In The Formosan Subterranean Termite, Paula Castillo

LSU Doctoral Dissertations

The Formosan subterranean termite, Coptotermes formosanus, is a eusocial insect species. Its members live in colonies consisting of reproductive (queen and king) and non-reproductive individuals (workers and soldiers). Olfaction is an essential sense for the social life of many insects. However, in termites, little is known about how olfactory cues are perceived in the peripheral sensory system (antennae) and processed in the central nervous system (brain) to elicit different behavioral responses across castes. In this study, we investigated the olfactory system in all castes (soldiers, workers, and reproductive alates), from the antennal and brain morphology to the antennal gene …


Integrating Behavioral Research Findings With A Liberal Arts Paradigm, Jonathan Peterson Jul 2023

Integrating Behavioral Research Findings With A Liberal Arts Paradigm, Jonathan Peterson

LSU Master's Theses

This paper explores the role of behavioral research in understanding the complexity and relevance of creativity. A brief history of the liberal arts and its current application is followed by a discussion of the importance of variability in generating novel and diverse responses, challenging the notion that creativity is solely a product of innate talent. The effects of reinforcement on variability, and how it relates to a complex relationship between reinforcement and the probability of variable responding leads to a discussion of how the combination of previously trained behaviors can lead to creative problem-solving, emphasizing the role of combinatory behavior …


What Happens Online Doesn't Stay Online: Female Elected Officials' Experiences With Online Harassment, Sarah M. Carpenter Jul 2023

What Happens Online Doesn't Stay Online: Female Elected Officials' Experiences With Online Harassment, Sarah M. Carpenter

LSU Doctoral Dissertations

Online harassment towards female elected officials is a prevalent problem that threatens women’s parity in local and state government. It is used for the purpose of diminishing women’s efficacy in government by stifling their voices in public spaces through behaviors that aim to belittle, embarrass and abuse women for existing in traditional masculine spaces that reify a white patriarchal social hierarchy. Female elected officials at all levels of government are susceptible to harassment on- and offline. The aim of this study expands current understandings of how online harassment affects female elected officials by focusing on online harassment experiences of women …


Neural Mechanisms Of Resiliency And Susceptibility After Repeated Social Defeat, Christy R. Wayne Jul 2023

Neural Mechanisms Of Resiliency And Susceptibility After Repeated Social Defeat, Christy R. Wayne

LSU Doctoral Dissertations

Social defeat is a powerful experience leading to drastic changes in physiology and behavior, many of which are negative. For example, repeated social defeat in vertebrates results in reduced reproductive success, sickness, and behavioral abnormalities that threaten individual survival and species persistence. However, little is known about what neural mechanisms are involved in determining whether an individual is resilient or susceptible to repeated social defeat stress. I used a resident-intruder experiment in the African cichlid fish, Astatotilapia burtoni, to create and investigate the behavior and neural correlates of these two opposing groups. Resilient fish used both searching and freezing behaviors …


Advancements In Middle School Agricultural Education: An Examination Of Emerging Trends And Exemplary Programs, Jacob P. Englin Jul 2023

Advancements In Middle School Agricultural Education: An Examination Of Emerging Trends And Exemplary Programs, Jacob P. Englin

LSU Master's Theses

Recent trends in agricultural education have demonstrated that the number of middle school programs and students has been increasing. Despite this, middle school agricultural education students, teachers, and programs often have been considered to be underserved. For example, teachers at this level have expressed that they often lacked the training and resources to meet the needs of this diverse learning population. Even so, middle school agricultural education teachers have continued to provide quality learning experiences for their students. In response, this investigation’s purpose was to examine current trends of middle school agricultural education and the quality of learning conducted by …


Stolen Land: A Marriage Of Text And Music In My Country By Hyo-Won Woo, Nae Rim Moon Jul 2023

Stolen Land: A Marriage Of Text And Music In My Country By Hyo-Won Woo, Nae Rim Moon

LSU Doctoral Dissertations

Hyo-won Woo, a renowned female composer from South Korea, is highly regarded for her contributions to Korean choral music. Woo’s My Country is an 80-minute cantata consisting of 14 movements. As a full-time resident composer for the National Chorus of Korea, Woo composed this work in honor of the March 1st Revolution. She utilized her signature style of storytelling, incorporating narration and solo performers to portray the hardships of Korea during Japan’s colonial era. The cantata takes the mood of Requiem as a poignant symbol of Korea’s painful loss of their country and includes text derived from the resistance efforts …


Learning Dynamic Information Of High-Dimensional Signal Time-Series Using Advanced Machine Learning/Artificial Intelligence, Guannan Liu Jul 2023

Learning Dynamic Information Of High-Dimensional Signal Time-Series Using Advanced Machine Learning/Artificial Intelligence, Guannan Liu

LSU Doctoral Dissertations

In this dissertation, we propose a novel simulation-based device-free indoor localization and tracking system using the received signal strength indicators (RSSIs) of WiFi signals as the input features. The Feko channel-propagation simulation software is used to process the RSSI maps of the given arbitrary indoor geometry. In order to learn the dynamic information of high-dimensional RSSI time-series, we propose three procedures for the localization and dynamic tracking system.

First, The indoor geometry is partitioned into several equi-size zones and the localization problem is treated as the typical \multi-classification" problem. The advanced machine-learning techniques such as decision tree (DT) classifier, random …


Integrating Cultivar Resistance And Entomopathogens For Pest Management Of Sweetpotato Weevil, Cylas Formicarius Elegantulus (Summers), Schyler M. Lee Jul 2023

Integrating Cultivar Resistance And Entomopathogens For Pest Management Of Sweetpotato Weevil, Cylas Formicarius Elegantulus (Summers), Schyler M. Lee

LSU Master's Theses

Sweetpotato, Ipomoea batatas (L.) Lam, is the number one vegetable crop in Louisiana, producing 21,178 kg/ha in the year 2021. The sweetpotato weevil, Cylas formicarius elegantulus (Summers), is an economically important pest of sweetpotato. C. formicarius elegantulus females lay eggs into feeding holes on the storage root surface. Larvae then hatch and tunnel through the sweetpotato flesh where they complete their development. This cryptic-natured brentid can cause up to 100% yield loss when left unmanaged. The Louisiana Department of Agriculture and Forestry mandates protocols to limit C. formicarius elegantulus spread (e.g., clean seed, pheromone trapping, and quarantines); however, scheduled chemical …


The Ọkụmkpọ Masquerades Of The Afikpo Society Of Southeastern Nigeria: An Art Form And An Instrument Of Social Control., Chinenye Miriam Emelogu Jul 2023

The Ọkụmkpọ Masquerades Of The Afikpo Society Of Southeastern Nigeria: An Art Form And An Instrument Of Social Control., Chinenye Miriam Emelogu

LSU Master's Theses

Masquerade performances are prevalent in West Africa, but they hold particular importance among the Igbo of Southeastern Nigeria. This thesis explores the cultural significance and artistic expressions of Okunkpo masquerade at Afikpo, a sub-Igbo group in Nigeria. It demonstrates how Okunkpo has served as a mechanism of social control using humorous skits, storytelling and dance up to the 21st century. Okunkpo is an elaborate and the most attended masquerade performance at Afikpo. It appears only once in a year and is exclusively reserved for male initiates. Its popularity draws audience from far and near. As a community theatre, Okunkpo …


Residential Building Flood Risk Assessment And The Benefits Of Home Elevation, Ayat Al Assi Jul 2023

Residential Building Flood Risk Assessment And The Benefits Of Home Elevation, Ayat Al Assi

LSU Doctoral Dissertations

Evaluating flood risk is an essential component of understanding and increasing community resilience. A robust approach for quantifying flood risk in terms of average annual loss (AAL) in dollars is needed to provide valuable information for stakeholder decision-making inside and outside the special flood hazard area (SFHA, which corresponds to the 100-year floodplain). To further inform flood mitigation strategies, quantifying flood risk reduction with home elevation above an initial first-floor height (FFH0) and the cost effectiveness of federal mitigation assistance for elevation are important steps to enhance awareness of the effect of elevation in reducing flood risk. …


Expressing Outrage, Re-Inventing Hope: Performing Nationhood In Nigerian Standup Comedy., Babasinmisola Fadirepo Jul 2023

Expressing Outrage, Re-Inventing Hope: Performing Nationhood In Nigerian Standup Comedy., Babasinmisola Fadirepo

LSU Doctoral Dissertations

The intersection of the Nigerian national identity and popular culture has been overwhelmingly located in the Nigerian movie industry and the Afrobeats, the flourishing Nigerian popular music. Further, when intervention about the Nigerian national identity is located within standup comedy performances, such analysis is vastly linguistic analysis of the performance. Through the lens of performance studies, this dissertation extends the discussion of the Nigerian national identity to standup comedy performances. In addition to the linguistic analysis of select Nigerian standup comedy performances, this work considers the location, costumes of comic acts, and the settings of the performance studied. Simply, this …


Autism, Comorbidities, And Adaptive Functioning: A Potential Moderator, Joshua J. Montrenes Jul 2023

Autism, Comorbidities, And Adaptive Functioning: A Potential Moderator, Joshua J. Montrenes

LSU Doctoral Dissertations

Deficits in adaptive functioning and the presence of comorbid symptomatology are both commonly associated with autism spectrum disorder (ASD). Previous research has identified relationships between functional level (e.g., intellectual quotient [IQ], adaptive functioning [AF]) and comorbid symptomatology in ASD. However, further insight into the relationship between AF, comorbid psychopathology, and ASD is unclear. Specifically, how AF affects the relationship between ASD and comorbid conditions is not well understood. Whether AF moderates the relationship between autism symptom severity and comorbid symptom severity in toddlers with ASD was examined. ASD symptom severity positively correlated with comorbid symptom severity across domains and negatively …


Preliminary Validation Of Digital Photography To Assess The Home Food Environment, Daniela Quan, Isaac Michael, Elizabeth Gollub Jul 2023

Preliminary Validation Of Digital Photography To Assess The Home Food Environment, Daniela Quan, Isaac Michael, Elizabeth Gollub

Faculty Publications

The home food environment (HFE), the availability and accessibility of foods and food products within the home, has a strong influence on healthy eating behaviors. Studies assessing the HFE commonly utilize a home food inventory (HFI) for data collection. However, this approach tends to be burdensome for participants. This study validated a low-burden digital photo method for assessing the home food environment and confirmed that this method is preferred by participants. Study participants completed an HFI, submitted photos of household foods, then identified preference for the HFI or photo reporting method. Researchers completed an HFI based on each participant’s photo …


Evidence For Two Soybean Looper Strains In The United States With Limited Capacity For Cross-Hybridization, Rodney N. Nagoshi, Jeffrey A. Davis, Robert L. Meagher, Fred R. Musser, Graham P. Head, Hector Portillo, Henry Teran Jul 2023

Evidence For Two Soybean Looper Strains In The United States With Limited Capacity For Cross-Hybridization, Rodney N. Nagoshi, Jeffrey A. Davis, Robert L. Meagher, Fred R. Musser, Graham P. Head, Hector Portillo, Henry Teran

Faculty Publications

The noctuid moth soybean looper (SBL), Chrysodeixis includens (Walker) is an economically important pest of soybeans (Glycine max (L.) Merr.) in the southeastern United States. It has characteristics that are of particular concern for pest mitigation that include a broad host range, the capacity for annual long-distance flight, and resistance in some populations to important pesticides such as pyrethroids and chitin synthesis inhibitor. The biology of SBL in the United States resembles that of the fellow noctuid fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith), a major pest of corn and several other crops. FAW exhibits a population structure in that …


Louisiana Agriculture Magazine, Summer 2023 Jul 2023

Louisiana Agriculture Magazine, Summer 2023

Louisiana Agriculture

Rice, alligators and sugarcane are quintessential Louisiana products, and LSU AgCenter researchers and extension agents devote themselves to helping the producers who grow them. Economists are finding ways to improve the market for alligators while specialists focus on innovation in the sugar industry and creating new varieties of rice.

AgCenter researchers also have an eye on the natural world. They are protecting the roseau cane that thrives on the coast and the ironwood trees of Guam. All these efforts are detailed in this issue of Louisiana Agriculture magazine.


Substantially Enhanced Landscape Carbon Sink Due To Reduced Terrestrial-Aquatic Carbon Transfer Through Soil Conservation In The Chinese Loess Plateau, Lishan Ran, Nufang Fang, Xuhui Wang, Shilong Piao, Chun Ngai Chan, Siliang Li, Yi Zeng, Zhihua Shi, Mingyang Tian, Yi Jun Xu, Junyu Qi, Boyi Liu Jul 2023

Substantially Enhanced Landscape Carbon Sink Due To Reduced Terrestrial-Aquatic Carbon Transfer Through Soil Conservation In The Chinese Loess Plateau, Lishan Ran, Nufang Fang, Xuhui Wang, Shilong Piao, Chun Ngai Chan, Siliang Li, Yi Zeng, Zhihua Shi, Mingyang Tian, Yi Jun Xu, Junyu Qi, Boyi Liu

Faculty Publications

Soil conservation is of global importance, as accelerated soil erosion by human activity is a primary threat to ecosystem viability. However, the significance and role of soil conservation in reshaping landscape carbon (C) accounting has not been comprehensively integrated in the terrestrial C sink. Here, we present the first integrated assessment of the modified terrestrial C sink and aquatic C transport due to soil conservation for the semiarid Chinese Loess Plateau (CLP), the world's most vulnerable region to soil erosion. We show a surprisingly low terrestrial-aquatic C transfer that offset the terrestrial net ecosystem productivity by only 7.5%, which we …


Obesogens And Obesity: State-Of-The-Science And Future Directions Summary From A Healthy Environment And Endocrine Disruptors Strategies Workshop, Jerrold J. Heindel, Jessica A. Alvarez, Ella Atlas, Matthew C. Cave, Vaia Lida Chatzi, David Collier, Barbara Corkey, Douglas Fischer, Michael I. Goran, Sarah Howard, Scott Kahan, Matthias Kayhoe, Suneil Koliwad, Catherine M. Kotz, Michele La Merrill, Tim Lobstein, Carey Lumeng, David S. Ludwig, Robert H. Lustig, Pete Myers, Angel Nadal, Leonardo Trasande, Leanne M. Redman, Matthew S. Rodeheffer, Robert M. Sargis, Jacqueline M. Stephens, Thomas R. Ziegler, Bruce Blumberg Jul 2023

Obesogens And Obesity: State-Of-The-Science And Future Directions Summary From A Healthy Environment And Endocrine Disruptors Strategies Workshop, Jerrold J. Heindel, Jessica A. Alvarez, Ella Atlas, Matthew C. Cave, Vaia Lida Chatzi, David Collier, Barbara Corkey, Douglas Fischer, Michael I. Goran, Sarah Howard, Scott Kahan, Matthias Kayhoe, Suneil Koliwad, Catherine M. Kotz, Michele La Merrill, Tim Lobstein, Carey Lumeng, David S. Ludwig, Robert H. Lustig, Pete Myers, Angel Nadal, Leonardo Trasande, Leanne M. Redman, Matthew S. Rodeheffer, Robert M. Sargis, Jacqueline M. Stephens, Thomas R. Ziegler, Bruce Blumberg

Division of Basic Science Faculty Publications

On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen research to review the state of the science regarding the role of obesogenic chemicals that might be contributing to the obesity pandemic. The workshop's objectives were to examine the evidence supporting the hypothesis that obesogens contribute to the etiology of human obesity; to discuss opportunities for improved understanding, acceptance, and dissemination of obesogens as contributors to the obesity pandemic; and to consider the need for future research and potential mitigation …


Current Discoveries And Future Implications Of Eating Disorders, Bing Feng, Jerney Harms, Emily Chen, Peiyu Gao, Pingwen Xu, Yanlin He Jul 2023

Current Discoveries And Future Implications Of Eating Disorders, Bing Feng, Jerney Harms, Emily Chen, Peiyu Gao, Pingwen Xu, Yanlin He

Division of Basic Science Faculty Publications

Eating disorders (EDs) are characterized by severe disturbances in eating behaviors and can sometimes be fatal. Eating disorders are also associated with distressing thoughts and emotions. They can be severe conditions affecting physical, psychological, and social functions. Preoccupation with food, body weight, and shape may also play an important role in the regulation of eating disorders. Common eating disorders have three major types: anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED). In some cases, EDs can have serious consequences for an individual’s physical and mental health. These disorders often develop during adolescence or early adulthood and affect …


Long-Term Capture Data Uncover Shifts In The Daily Activity Patterns Of Amazonian Birds, Cameron L. Rutt, Philip C. Stouffer, Bruna R. Amaral, David A. Luther Jul 2023

Long-Term Capture Data Uncover Shifts In The Daily Activity Patterns Of Amazonian Birds, Cameron L. Rutt, Philip C. Stouffer, Bruna R. Amaral, David A. Luther

Faculty Publications

Although the duration of biological rhythms varies from milliseconds to decades, daily cycles are especially widespread for individual organisms. These circadian rhythms are synchronized by light–dark cycles, which govern predictable changes in other microclimate variables. Despite the fixed, regular nature of these abiotic cycles at low latitudes, little is known about how different animals structure activity along these gradients. We used 25 years of capture–recapture data and ~ 25 000 unique captures to characterize ‘activity' (time of capture) for 65 species of Amazonian birds in the lowest forest stratum (0–2.5 m). To quantify vertical niche breadths, we also measured foraging …


Measuring In Vivo Adipose Tissue Kinetics In Humans Using The Deuterium (2h)-Labeling Approach, Dereck Kibodeaux, Jonathan Savoie, Eric Ravussin, Mark Fitch, Marc K. Hellerstein, Ursula White Jul 2023

Measuring In Vivo Adipose Tissue Kinetics In Humans Using The Deuterium (2h)-Labeling Approach, Dereck Kibodeaux, Jonathan Savoie, Eric Ravussin, Mark Fitch, Marc K. Hellerstein, Ursula White

Clinical Research Faculty Publications

White adipose tissue is a highly plastic organ that is necessary to maintain whole-body energy homeostasis. The adipose tissue mass and changes in the fat mass or distribution are regulated by changes in the synthesis and breakdown (i.e., turnover) of adipose cells and triacylglycerols. Evidence suggests that the manner and magnitude of subcutaneous adipose tissue expansion (i.e., hypertrophy vs. hyperplasia) and turnover can influence metabolic health, as adipogenesis has been implicated in the pathogenesis of obesity and related diseases. Despite the potential role of adipose turnover in human health, there is a lack of knowledge about the in vivo kinetics …


Current Status Of Us Soil Test Phosphorus And Potassium Recommendations And Analytical Methods, Sarah E. Lyons, Jason D. Clark, Deanna L. Osmond, Md Rasel Parvej, Austin W. Pearce, Nathan A. Slaton, John T. Spargo Jul 2023

Current Status Of Us Soil Test Phosphorus And Potassium Recommendations And Analytical Methods, Sarah E. Lyons, Jason D. Clark, Deanna L. Osmond, Md Rasel Parvej, Austin W. Pearce, Nathan A. Slaton, John T. Spargo

Faculty Publications

Soil testing is the foundation of fertilizer recommendations in the United States. Fertilizer recommendations have primarily been developed by land-grant universities with limited coordination among programs. The individual state approach to develop fertilizer recommendations has resulted in discrepancies in recommended soil sampling protocols, soil analysis methods, and fertilizer recommendations at similar soil nutrient levels. A national survey was developed to summarize the status of soil testing and fertility work in the United States to inform future collaborative efforts among states and regions and identify opportunities to harmonize recommendation guidelines. Topics included relevant funding, multi-state collaborations, state soil-test recommendations and related …


Exploring Barriers To Sars-Cov-2 Testing Uptake In Underserved Black Communities In Louisiana, Peter T. Katzmarzyk, Candice A. Myers, Michelle R. Nelson, Kara D. Denstel, Emily F. Mire, Robert L. Newton, Stephanie T. Broyles, John P. Kirwan Jul 2023

Exploring Barriers To Sars-Cov-2 Testing Uptake In Underserved Black Communities In Louisiana, Peter T. Katzmarzyk, Candice A. Myers, Michelle R. Nelson, Kara D. Denstel, Emily F. Mire, Robert L. Newton, Stephanie T. Broyles, John P. Kirwan

Division of Basic Science Faculty Publications

Objective: To collect qualitative data on approaches that can potentially reduce barriers to, and create strategies for, increasing SARS-CoV-2 testing uptake in underserved Black communities in Louisiana. Methods: A series of eight focus groups, including 41 participants, were conducted in primarily Black communities. The Nominal Group Technique (NGT) was used to determine perceptions of COVID-19 as a disease, access to testing, and barriers limiting testing uptake. Results: Common barriers to SARS-CoV-2 testing were identified as lack of transportation, misinformation/lack of information, lack of time/long wait times, fear of the test being uncomfortable and/or testing positive, the cost of testing, and …


Association Between Maternal And Infant Screen Time With Child Growth And Development: A Longitudinal Study, Chelsea L. Kracht, Leanne M. Redman, Jayne Bellando, Rebecca A. Krukowski, Aline Andres Jul 2023

Association Between Maternal And Infant Screen Time With Child Growth And Development: A Longitudinal Study, Chelsea L. Kracht, Leanne M. Redman, Jayne Bellando, Rebecca A. Krukowski, Aline Andres

Clinical Research Faculty Publications

Background: Sedentary screen time is an early, modifiable risk factor for obesity and poor child development. Objectives: To examine the relationship between maternal and infant screen time with child growth and development. Methods: Pregnant women were recruited for a cohort study related to maternal and infant development. Screen time was assessed in mothers during pregnancy, and subsequently in children at 3 months, 12 months, and 24 months of age. Child anthropometry was measured, and nuclear magnetic resonance quantified child fat mass. Fat mass index (FMI) was calculated. The Bayley Scales of Infant Development-III were used to assess child development. Linear …


A Feasibility Study Of The Combination Of Intranasal Insulin With Dulaglutide For Cognition In Older Adults With Metabolic Syndrome At High Dementia Risk – Study Rationale And Design, Tal Davidy, Iscka Yore, Tali Cukierman-Yaffe, Ramit Ravona-Springer, Abigail Livny, Orit H. Lesman-Segev, Yossi Azuri, Owen Carmichael, Dimitrios Kapogiannis, Henrik Zetterberg, Hung Mo Lin, Mary Sano, Michal Schnaider Beeri Jul 2023

A Feasibility Study Of The Combination Of Intranasal Insulin With Dulaglutide For Cognition In Older Adults With Metabolic Syndrome At High Dementia Risk – Study Rationale And Design, Tal Davidy, Iscka Yore, Tali Cukierman-Yaffe, Ramit Ravona-Springer, Abigail Livny, Orit H. Lesman-Segev, Yossi Azuri, Owen Carmichael, Dimitrios Kapogiannis, Henrik Zetterberg, Hung Mo Lin, Mary Sano, Michal Schnaider Beeri

Clinical Research Faculty Publications

Introduction: We present the rationale and design of a double-blind placebo-controlled feasibility trial combining intranasal insulin (INI) with dulaglutide, a GLP-1 receptor agonist, to improve cognition in older adults with metabolic syndrome (MetS) and mild cognitive impairment (MCI). Since both INI and dulaglutide have beneficial effects on the cerebrovascular disease (CVD), we anticipate that improved CVD will underlie the hypothesized cognitive benefits. Methods: This 12-months trial will include 80 older adults aged > 60 with MetS and MCI, randomized to 4 groups: INI/dulaglutide injection, intranasal placebo/dulaglutide injection, INI/placebo injection, and intranasal placebo/placebo injection. Feasibility of combining INI with dulaglutide will be …


Transcription Factor Pecs Mediates Agrobacterium Fabrum Fitness And Survival, George C. Nwokocha, Prava Adhikari, Asif Iqbal, Hannah Elkholy, William T. Doerrler, John C. Larkin, Anne Grove Jul 2023

Transcription Factor Pecs Mediates Agrobacterium Fabrum Fitness And Survival, George C. Nwokocha, Prava Adhikari, Asif Iqbal, Hannah Elkholy, William T. Doerrler, John C. Larkin, Anne Grove

Faculty Publications

The transcriptional regulator PecS is encoded by select bacterial pathogens. For instance, in the plant pathogen Dickeya dadantii, PecS controls a range of virulence genes, including pectinase genes and the divergently oriented gene pecM, which encodes an efflux pump through which the antioxidant indigoidine is exported. In the plant pathogen Agrobacterium fabrum (formerly named Agrobacterium tumefaciens), the pecS-pecM locus is conserved. Using a strain of A. fabrum in which pecS has been disrupted, we show here that PecS controls a range of phenotypes that are associated with bacterial fitness. PecS represses flagellar motility and chemotaxis, which are processes that are …


Reducing The Generation Time In Winter Wheat Cultivars Using Speed Breeding, Adam Schoen, Sydney Wallace, Meghan Fisher Holbert, Gina Brown-Guidera, Stephen Harrison, Paul Murphy, Nicholas Sanantonio, David Van Sanford, Richard Boyles, Mohamed Mergoum, Nidhi Rawat, Vijay Tiwari Jul 2023

Reducing The Generation Time In Winter Wheat Cultivars Using Speed Breeding, Adam Schoen, Sydney Wallace, Meghan Fisher Holbert, Gina Brown-Guidera, Stephen Harrison, Paul Murphy, Nicholas Sanantonio, David Van Sanford, Richard Boyles, Mohamed Mergoum, Nidhi Rawat, Vijay Tiwari

Faculty Publications

Reducing generation time is critical to achieving the goals of genetic gain in important crops like wheat (Triticum aestivum). Speed breeding (SB) has been shown to considerably reduce generation times in crop plants. Unlike spring wheat cultivars, winter wheat varieties require typically 6–9 weeks of cold treatment, called vernalization, for flowering which extends the generation time for the development of improved winter wheat cultivars. Here, we optimized the SB method using a set of 48 diverse soft red winter wheat (SRWW) cultivars by testing vernalization duration, light and temperature requirements, and the viability of seeds harvested after different durations post-anthesis …