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Consumer Behavior Analysis Approach To Teacher Choice Of Reading Interventions, Rochelle N. Picardo
Consumer Behavior Analysis Approach To Teacher Choice Of Reading Interventions, Rochelle N. Picardo
LSU Doctoral Dissertations
The use of Evidence-based Practices (EBPs) in schools is heavily emphasized in educational research and policy; however, many teachers do not use EBPs for reading instruction and intervention. Previous research on the limited use of EBPs in classrooms has primarily focused on teacher characteristics, such as their attitudes or beliefs toward these practices. As an alternative to this view, this study applied a behavioral economic approach to understanding teacher choice (i.e., EBPs over other alternatives, such as interventions with a base of limited empirical support; low-value practices [LVPs]). Hypothetical Intervention Choice Tasks were developed and used to evaluate how both …
The Relationship Between Communicative And Social Deficits And Challenging Behavior In Angelman Syndrome, Cassie Chanel Feck
The Relationship Between Communicative And Social Deficits And Challenging Behavior In Angelman Syndrome, Cassie Chanel Feck
LSU Doctoral Dissertations
Angelman Syndrome (AS) is a low-incidence neurodevelopmental disorder characterized by deficits in speech, motor, and social development as well as related differences in challenging behavior, seizures, and sleep issues. AS has a known genetic etiology and research conducted with this population has overwhelmingly focused on exploring the genetic and biological underpinnings of the disorder (e.g., applied gene therapies). At present, far less research on supporting the social, communicative, and behavioral needs of this population and how these specific deficits contribute to the individual’s overall functioning. The goals of this study were to characterize the use of Augmentative and Alternative Communication …
Speculative Telephone: Oral Historians And Digital Librarians On How Libraries Could Be, Kae Kratcha
Speculative Telephone: Oral Historians And Digital Librarians On How Libraries Could Be, Kae Kratcha
Journal of Critical Digital Librarianship
In the summer of 2023, librarian and oral historian Kae Bara Kratcha interviewed three oral historians about their relationships to libraries and their dreams for what digital libraries could be. Then they played portions of each oral historian interview for a digital librarian and asked the librarian to speculate about what their jobs and lives would be like if they implemented the oral historians' ideas about digital libraries. “Speculative Telephone: Oral Historians and Digital Librarians on How Libraries Could Be” is eleven edited audio tracks of wide-ranging conversation on topics like public space, online communities, library anxiety, relationships with library …
Desire Paths In The Information Landscape, Victoria Van Hyning, Mason A. Jones, Travis Wagner
Desire Paths In The Information Landscape, Victoria Van Hyning, Mason A. Jones, Travis Wagner
Journal of Critical Digital Librarianship
Libraries and archives serve so many different users who come to information institutions with various perspectives, needs, experiences, and desires around accessing physical or digital collections. While our users may find what they are looking for immediately, many have to beat their own paths through complex systems and metadata that doesn’t align with their needs. Their search strategies may leave digital “desire paths”–alternative routes through the information landscape that can show us how to better meet their needs. This article covers three scenarios where users’ desire paths can be seen or where gaps around user experience can be better addressed. …
The Product Of Distributions And Stochastic Differential Equations Arising From Powers Of Infinite Dimensional Brownian Motions, Un Cig Ji, Hui-Hsiung Kuo, Hara-Yuko Mimachi, Kimiaki Saitô
The Product Of Distributions And Stochastic Differential Equations Arising From Powers Of Infinite Dimensional Brownian Motions, Un Cig Ji, Hui-Hsiung Kuo, Hara-Yuko Mimachi, Kimiaki Saitô
Journal of Stochastic Analysis
No abstract provided.
Editors' Introduction, Leah Powell Duncan, Janina Mueller, Rachel Starry, Sl Ziegler, Emily M. Zinger
Editors' Introduction, Leah Powell Duncan, Janina Mueller, Rachel Starry, Sl Ziegler, Emily M. Zinger
Journal of Critical Digital Librarianship
Editors' Introduction. Special Issue, "Turning it Off and Back On Again: Speculative Digital Librarianship"
Examining The Relations Between Number Of Opportunities To Self-Monitor And Self-Monitoring On-Task Or Accuracy In Children, Alison Ruby
LSU Doctoral Dissertations
Difficulties in academic achievement have been linked to adverse outcomes such as increased problem behavior and delays in development (Hinshaw, 1992). Early education should include training to self-monitor, as self-monitoring can improve academic performance and has a wide range of uses (Harris et al., 2005). Previous literature typically uses frequent self-monitoring opportunities ranging from every 30 seconds to 1 minute. The purpose of this study was to identify the effects of the number of self-monitoring opportunities when self-monitoring on-task behavior and self-monitoring accuracy of task completion, on-task behavior, disruptions, and accuracy of self-monitoring (types of errors) and determine the preferences …
Age, Growth, And Mortality Of Blackfin Tuna In The Gulf Of Mexico, E. M. Gutierrez, E. T. Lang, M. S. Lovell, J. Lang, B. J. Falterman, S. R. Midway, M. A. Dance
Age, Growth, And Mortality Of Blackfin Tuna In The Gulf Of Mexico, E. M. Gutierrez, E. T. Lang, M. S. Lovell, J. Lang, B. J. Falterman, S. R. Midway, M. A. Dance
Faculty Publications
Objective: An otolith-based aging approach was used to evaluate age and growth relationships, sexual dimorphism in growth, and derive mortality estimates for Blackfin Tuna Thunnus atlanticus in the Gulf of Mexico (GOM). Methods: Blackfin Tuna (n = 395) were sampled from recreational fisheries and aged from 0 to 13 years, representing an increase over previous estimates of longevity for the species. Result: Rapid growth was exhibited during the first two years of life, and the Richards growth function provided a better fit (L∞ = 907 mm, k = 0.112 /year, a = 1.05, b = 0.25) to the data compared …
Consumer Engagement In Fashion Circularity In China: Exploring Consumer Online Fashion Resale Through The Lens Of Social Practice Theory, Sujun Liu, Chuanlan Liu, Chunmin Lang
Consumer Engagement In Fashion Circularity In China: Exploring Consumer Online Fashion Resale Through The Lens Of Social Practice Theory, Sujun Liu, Chuanlan Liu, Chunmin Lang
Faculty Publications
Fashion resale has emerged as a notable strategy for the fashion industry to reduce its environmental footprint by promoting fashion circularity. Despite extensive research on consumer awareness of resale and the purchase of pre-owned items, there remains a gap in understanding the factors that influence consumers’ participation in resale markets, encompassing both selling and buying practices. Drawing on social practice theory (SPT), this qualitative study examines the nuanced factors influencing consumers’ online resale practices and investigates how online fashion resale practices (OFRPs) have become integrated into their daily consumption patterns. In-depth interviews were conducted with thirty experienced Chinese consumers engaged …
Improving School Discipline, Climate, And Culture: Interactive Guidance For Schools And Districts, Gwendolyn Murray
Improving School Discipline, Climate, And Culture: Interactive Guidance For Schools And Districts, Gwendolyn Murray
Reports
This interactive guide is designed to support K-12 school districts and schools to proactively improve school environments by supporting teacher development and building systems to promote positive student behaviors. Practices and strategies in the guide can be used to reduce exclusionary discipline and improve school climate and culture. Activities enable users to think critically about school discipline and invest in data-driven and prevention-oriented systems to address students' challenging and problematic behaviors.
Hepatic Interoception In Health And Disease, Hans Rudolf Berthoud, Heike Münzberg, Christopher D. Morrison, Winfried L. Neuhuber
Hepatic Interoception In Health And Disease, Hans Rudolf Berthoud, Heike Münzberg, Christopher D. Morrison, Winfried L. Neuhuber
Division of Basic Science Faculty Publications
The liver is a large organ with crucial functions in metabolism and immune defense, as well as blood homeostasis and detoxification, and it is clearly in bidirectional communication with the brain and rest of the body via both neural and humoral pathways. A host of neural sensory mechanisms have been proposed, but in contrast to the gut-brain axis, details for both the exact site and molecular signaling steps of their peripheral transduction mechanisms are generally lacking. Similarly, knowledge about function-specific sensory and motor components of both vagal and spinal access pathways to the hepatic parenchyma is missing. Lack of progress …
Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev
Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev
Clinical Research Faculty Publications
Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE™) 2 trial tested translation of these findings to humans. CALERIE™ randomized healthy, nonobese men and premenopausal women (age 21–50y; BMI 22.0–27.9 kg/m2), to 25% CR or ad-libitum (AL) control (2:1) for 2 years. Prior analyses of CALERIE™ participants' blood chemistries, immunology, and epigenetic data suggest the 2-year CR intervention slowed biological aging. Here, we extend these analyses to test effects of CR on telomere length (TL) attrition. TL was quantified in blood samples collected at baseline, 12-, …
Phytochemical Profiling And Bioactive Potential Of Grape Seed Extract In Enhancing Salinity Tolerance Of Vicia Faba, Doaa E. Elsherif, Fatmah A. Safhi, Prasanta K. Subudhi, Abdelghany S. Shaban, Mai A. El-Esawy, Asmaa M. Khalifa
Phytochemical Profiling And Bioactive Potential Of Grape Seed Extract In Enhancing Salinity Tolerance Of Vicia Faba, Doaa E. Elsherif, Fatmah A. Safhi, Prasanta K. Subudhi, Abdelghany S. Shaban, Mai A. El-Esawy, Asmaa M. Khalifa
Faculty Publications
Salinity stress poses a significant threat to crop productivity worldwide, necessitating effective mitigation strategies. This study investigated the phytochemical composition and potential of grape seed extract (GSE) to mitigate salinity stress effects on faba bean plants. GC–MS analysis revealed several bioactive components in GSE, predominantly fatty acids. GSE was rich in essential nutrients and possessed a high antioxidant capacity. After 14 days of germination, GSE was applied as a foliar spray at different concentrations (0, 2, 4, 6, and 8 g/L) to mitigate the negative effects of salt stress (150 mM NaCl) on faba bean plants. Foliar application of 2–8 …
Stacked Noise Reduction Auto Encoder–Ocean: A Novel Personalized Recommendation Model Enhanced, Bixi Wang, Wenfeng Zheng, Ruiyang Wang, Siyu Lu, Lirong Yin, Lei Wang, Zhengtong Yin, Xinbing Chen
Stacked Noise Reduction Auto Encoder–Ocean: A Novel Personalized Recommendation Model Enhanced, Bixi Wang, Wenfeng Zheng, Ruiyang Wang, Siyu Lu, Lirong Yin, Lei Wang, Zhengtong Yin, Xinbing Chen
Faculty Publications
With the continuous development of information technology and the rapid increase in new users of social networking sites, recommendation technology is becoming more and more important. After research, it was found that the behavior of users on social networking sites has a great correlation with their personalities. The five characteristics of the OCEAN personality model can cover all aspects of a user’s personality. In this research, a micro-directional propagation model based on the OCEAN personality model and a Stacked Denoising Auto Encoder (SDAE) was built through the application of deep learning to a collaborative filtering technique. Firstly, the dimension of …
Evaluating The Relationship Between Parent-Adolescent Communication, Social Media Use, And Psychological Well-Being In Adolescents, Johannah Smith
Evaluating The Relationship Between Parent-Adolescent Communication, Social Media Use, And Psychological Well-Being In Adolescents, Johannah Smith
LSU Doctoral Dissertations
Adolescents, particularly teenage girls, use social media substantially more than any other age group (Boneva et al., 2006; Gross, 2004; Padilla-Walker et al., 2020). Greater social media use has been linked to internalizing and externalizing problems; however, specific social media behavior and the relation to internalizing and externalizing problems is unknown. Additionally, how parent-adolescent communication impacts the relationships has not been explored. This is concerning as specific social media behavior, such as ruminating with peers and general social media addiction, has been linked to adolescents’ psychological well-being. (Sarmiento et al., 2020; Shensa et al., 2017; Nesi et al., 2020). The …
Hydrometeorological Drivers Of The 2023 Louisiana Water Crisis, P. W. Miller, M. Hiatt
Hydrometeorological Drivers Of The 2023 Louisiana Water Crisis, P. W. Miller, M. Hiatt
Faculty Publications
During summer and fall 2023, Louisiana experienced a historic local drought while dry conditions elsewhere in the central US withheld vital runoff from the Mississippi River, leading to below-normal discharge into the Gulf of Mexico. Thus, by late October 2023, Louisiana was gripped by two super-imposed water crises: a severe local drought and saltwater contamination in the Mississippi River channel. This study frames the development of the water emergency through the lens of flash drought using the Evaporative Demand Drought Index (EDDI). The EDDI shows south Louisiana experience a flash drought during June 2023, while the Mississippi River basin was …
Top-Down Control Of Ammonia Oxidizers By Grazing In The North Pacific, Silin Ni, Min Nina Xu, Moge Du, Edward A. Laws, Shuh Ji Kao
Top-Down Control Of Ammonia Oxidizers By Grazing In The North Pacific, Silin Ni, Min Nina Xu, Moge Du, Edward A. Laws, Shuh Ji Kao
Faculty Publications
The impact of grazing pressure on ammonia oxidizers (AO) has never been quantified in the field. Here we develop a new method to quantify the grazing rates on AO in aquatic systems. We introduce 15NH4+ tracer into the traditional dilution experiments to measure AO's apparent growth rates by using the end-product of 15NH4+ oxidation, that is, 15NOx−. Field studies in the North Pacific revealed that 15NOx− in the end-product was sensitive enough to detect AO's grazing rates. Experiments from the lower euphotic zone showed NH4+ replete growth rates of 0.40 …
Farmer's Adaptive Capacity And Adoption Of Strategies To Climate Change Among Mountain Communities In Nepal, Tanvir Hossain
Farmer's Adaptive Capacity And Adoption Of Strategies To Climate Change Among Mountain Communities In Nepal, Tanvir Hossain
LSU Master's Theses
Climate change presents significant challenges to agriculture worldwide, particularly where farming is central to livelihoods. This phenomenon has been linked to decreasing crop yields due to rising temperatures and reduced rainfall, particularly affecting low-income countries with limited adaptive capabilities. Grasping how farmers perceive climate change is essential for developing effective adaptation strategies to lessen its adverse impacts. This study concentrated on investigating the perceptions and adaptive strategies employed by smallholder farmers in Nepal's Mustang district, utilizing primary data sources. Data from 131 randomly selected households were gathered through structured interviews, while focus group discussions provided qualitative insights into farmers' views …
Methods To Manage Survey Error Within Economic Contribution Analysis, Madison Jane Plaisance
Methods To Manage Survey Error Within Economic Contribution Analysis, Madison Jane Plaisance
LSU Master's Theses
The primary objective of this research was to employ strategical methodological approaches to assess the economic value of specific sub-sectors of the green industry within Louisiana. I specifically focused on addressing errors associated with utilizing survey data as the primary data source in such analyses and utilizing approaches such as post-survey stratification and bootstrapping techniques to mitigate these errors.
To achieve this aim, a group of green industry professionals and I selected sectors for analysis based on horticultural licenses issued by the Louisiana Department of Agriculture and Forestry (LDAF). Through collaboration with advisors from the Louisiana Nursery and Landscape Association …
Preserving The Historic And Cultural Music Of Louisiana Through School Music: An Ethnographic Case Study, Christopher S. Song
Preserving The Historic And Cultural Music Of Louisiana Through School Music: An Ethnographic Case Study, Christopher S. Song
LSU Doctoral Dissertations
The purpose of this ethnographic case study was to examine the lives of teachers, students, community members, and culture bearers within a musical community located in South Central Louisiana. The geographic area of focus in this research was Vermilion Parish and its surrounding area, known as Acadiana, the heart of Creole and Cajun culture where Traditional Louisiana Music finds its origins. Participants’ intrinsic cultural understandings of Louisiana’s music and impact on school music programs was examined through ethnographic interview and observation. A resource pedagogy known as funds of knowledge was used as a theoretical framework meant to maintain participants’ intrinsic …
Extreme Climate Events And Agricultural Commodity Markets, Mohammad Abir Chowdhury Shovon
Extreme Climate Events And Agricultural Commodity Markets, Mohammad Abir Chowdhury Shovon
LSU Master's Theses
This article investigates the impact of extreme climate events on U.S. agricultural commodity markets, specifically focusing on corn and soybeans. Using event study methods and a comprehensive dataset of 254 extreme climate events for corn as well as 250 extreme climate events for soybeans in top ten corn & soybeans producing states of the USA between 1995 and 2023, we examine how storms, floods, extreme temperatures, and droughts affect the abnormal returns of these commodities. Our findings indicate that 22.04% of climate events significantly impact corn returns and 21.20% of climate events have significant impact on soybeans returns. Notably, extreme …
Characteristics Influencing Enrollment Choices: A Mixed Methods Analysis Of Factors That Influence Black Students' Decision To Enroll In College Of Agriculture Programs, Jennifer L. Brown
Characteristics Influencing Enrollment Choices: A Mixed Methods Analysis Of Factors That Influence Black Students' Decision To Enroll In College Of Agriculture Programs, Jennifer L. Brown
LSU Doctoral Dissertations
This study aims to identify the barriers that affect Minority enrollment in agriculture, particularly focusing on increasing the enrollment of Black students. There is a significant concern regarding the gap between Black individuals and agriculture enrollment in post-secondary agriculture programs at land-grant institutions. The purpose of this mixed method phenomenology was to (1) identify factors that influence the decision of Black students to enroll in the College of Agriculture and (2) uncover the societal and economic influences that continue to serve as barriers to Black students’ enrolling in agriculture. The quantitative portion of the investigation utilized a web-based instrument structured …
Identifying Self-Efficacy Factors Of Agriscience Teachers When Working With Supervised Agricultural Experiences For Students With Disabilities, Saralyn L. Smith
Identifying Self-Efficacy Factors Of Agriscience Teachers When Working With Supervised Agricultural Experiences For Students With Disabilities, Saralyn L. Smith
LSU Master's Theses
The number of students receiving disability services annually in the U.S. has increased in the last decade. Even with this growing population of students with disabilities, research continues to show a lack of confidence of School Based Agricultural Education (SBAE) teachers in their ability and skills to include these students. The purpose of this qualitative study was to describe the factors that influence how SBAE teachers support students with disabilities in Supervised Agricultural Experience Programs and identify perceived obstacles SBAE teachers have regarding working with students with disabilities. Semi-structed interviews were conducted with twelve SBAE teachers to understand their lived …
Learning Proximal Operators With Gaussian Process And Adaptive Quantization In Distributed Optimization, Aldo Duarte Vera Tudela
Learning Proximal Operators With Gaussian Process And Adaptive Quantization In Distributed Optimization, Aldo Duarte Vera Tudela
LSU Doctoral Dissertations
In networks consisting of agents communicating with a central coordinator and working together to solve a global optimization problem in a distributed manner, the agents are often required to solve private proximal minimization subproblems. Such a setting often requires a further decomposition method to solve the global distributed problem, resulting in extensive communication overhead. In networks where communication is expensive, it is crucial to reduce the communication overhead of the distributed optimization scheme. Integrating Gaussian processes (GP) as a learning component to the Alternating Direction Method of Multipliers (ADMM) has proven effective in learning each agent's local proximal operator to …
Decay Spectroscopy Of 134sb Using X-Array And Saturn, Graeme E. Morgan
Decay Spectroscopy Of 134sb Using X-Array And Saturn, Graeme E. Morgan
LSU Doctoral Dissertations
The ground-state decay of 134Sb is reported by the current evaluated nuclear data to be dominated by a 0-→0+ first-forbidden Gamow-Teller transition to the ground state of 134Te. In 2013, a recoil-ion time-of-flight (RI-TOF) spectroscopy measurement of 134Sb with the Beta-decay Paul Trap (BPT) indicated that the ground-state feeding of 134Te is weaker than reported. Simulation work of 134Sb ground-state decays replicated the RI-TOF results with the addition of a theorised 5-MeV state that was fed with ~17% of the total β-decay strength. To search for higher energy states and transitions that …
Struggling To Be Positive Problem Solvers – A Study On The Relationship Of Elementary Mathematical Self-Concept, Gender, Learner Identification, And Productive Struggle Trajectories On Constructed Response Questions When Being Taught With A Standardized Curriculum, Kali D. Rogers
LSU Doctoral Dissertations
Mathematical word problems are some of the most difficult problems for students to solve due to their complexity and relationship to real-world situations (Şahin et al., 2014; Verschaffel et al., 2020). With math being known for right-or-wrong answers, these open-ended questions cause much confusion and frustration, specifically for students of various subgroups. In the last several decades, educational teaching expectations have shifted from engaging, self-created learning to robotic and redundant curriculum expectations that induce a ‘teaching to the test’ environment (Shafiyeva, 2021). Mathematics is the powerhouse of where students can experience and succeed with productive struggle learning that teaches the …
It’S Britney, Bitch, Mary Hyepock
It’S Britney, Bitch, Mary Hyepock
LSU Doctoral Dissertations
This dissertation engages public rhetorics surrounding pop princess Britney Spears as a case study for examining the rhetoricity of bodily autonomy. Bodily autonomy is commonly understood as the legal right to control what happens to one’s body without external influence or coercion. However, one’s legal access to bodily autonomy is produced, negotiated, and maintained through discourse. In other words, one’s access to so-called “ownership” over their body and agency to make decisions about it is deeply tied to the gendered and racialized symbolic production of citizenship in the United States. Utilizing a reproductive justice framework, I investigate how Britney Spears’ …
An Analysis Of The Musical Gestures In Osvaldo Golijov’S The Dreams And Prayers Of Isaac The Blind And Their Relationship To The Kabbalah Sefirot, Jeremy Gdaniec
LSU Doctoral Dissertations
Osvlado Golijov’s The Dreams and Prayers of Isaac the Blind, scored for klezmer clarinet and string quartet, remains one of his most influential works since its premier in 1994. Inspiration for the work came from the writings of Rabbi Isaac the Blind, a prominent 13th century figurehead in the branch of Jewish mysticism known as Kabbalah. In Kabbalah, symbols known as the sefirot are emanations of creation and the key to unlocking the divine secrets of the God-head. The analysis presented in this document combines musical gesture theory with Kabbalistic concepts for new perspectives on Golijov’s …
Multiphoton Quantum Sensing, Fatemeh Mostafavikhatam
Multiphoton Quantum Sensing, Fatemeh Mostafavikhatam
LSU Doctoral Dissertations
While the fundamental principles of light-matter interaction are well-understood and drive countless technologies, the world of multiphoton processes remains a fascinating puzzle, holding the potential to drastically alter our understanding of how light interacts with matter at its most basic level [1–4]. This rich interplay of light and matter unveils novel phenomena that can be harnessed for sensing with exceptional precision, as exemplified by multiphoton quantum sensing. This thesis delves into the applications of multiphoton quantum protocols, particularly in imaging, communication, and plasmonic sensing, to surpass classical limitations and achieve enhanced sensitivity. We explore the potential of multiphoton quantum processes, …
Temporal Dynamics Of The Multi-Omic Response To Endurance Exercise Training, David Amar, Nicole R. Gay, Pierre M. Jean-Beltran, Dam Bae, Surendra Dasari, Courtney Dennis, Charles R. Evans, David A. Gaul, Olga Ilkayeva, Anna A. Ivanova, Maureen T. Kachman, Hasmik Keshishian, Ian R. Lanza, Ana C. Lira, Michael J. Muehlbauer, Venugopalan D. Nair, Paul D. Piehowski, Jessica L. Rooney, Kevin S. Smith, Cynthia L. Stowe, Bingqing Zhao, Natalie M. Clark, David Jimenez-Morales, Malene E. Lindholm, Gina M. Many, James A. Sanford, Gregory R. Smith, Nikolai G. Vetr, Tiantian Zhang, Jose J. Almagro Armenteros, Julian Avila-Pacheco, Nasim Bararpour, Yongchao Ge, Zhenxin Hou
Temporal Dynamics Of The Multi-Omic Response To Endurance Exercise Training, David Amar, Nicole R. Gay, Pierre M. Jean-Beltran, Dam Bae, Surendra Dasari, Courtney Dennis, Charles R. Evans, David A. Gaul, Olga Ilkayeva, Anna A. Ivanova, Maureen T. Kachman, Hasmik Keshishian, Ian R. Lanza, Ana C. Lira, Michael J. Muehlbauer, Venugopalan D. Nair, Paul D. Piehowski, Jessica L. Rooney, Kevin S. Smith, Cynthia L. Stowe, Bingqing Zhao, Natalie M. Clark, David Jimenez-Morales, Malene E. Lindholm, Gina M. Many, James A. Sanford, Gregory R. Smith, Nikolai G. Vetr, Tiantian Zhang, Jose J. Almagro Armenteros, Julian Avila-Pacheco, Nasim Bararpour, Yongchao Ge, Zhenxin Hou
Clinical Research Faculty Publications
Regular exercise promotes whole-body health and prevents disease, but the underlying molecular mechanisms are incompletely understood1–3. Here, the Molecular Transducers of Physical Activity Consortium4 profiled the temporal transcriptome, proteome, metabolome, lipidome, phosphoproteome, acetylproteome, ubiquitylproteome, epigenome and immunome in whole blood, plasma and 18 solid tissues in male and female Rattus norvegicus over eight weeks of endurance exercise training. The resulting data compendium encompasses 9,466 assays across 19 tissues, 25 molecular platforms and 4 training time points. Thousands of shared and tissue-specific molecular alterations were identified, with sex differences found in multiple tissues. Temporal multi-omic and multi-tissue analyses revealed expansive biological …