Digital Commons Network^™

Characterizing The Role Off The Sp1/Klf Transcription Factor Huckebein In The Drosophila Melanogaster Ventral Nerve Cord, Benjamin Almond

Distinguished Undergraduate Researcher Program

Over the course of embryonic development, the ectodermal cell layer gives rise to a vast array of neurons and glia patterned across the central nervous system (CNS). Neurulation and specification is achieved in the ectoderm through temporospatial patterns of transcription factor (TF) expression, many of which are conserved across evolutionary history. These conserved regulatory motifs allow the use of Drosophila melanogaster to study the mechanisms of neurodevelopment across the animal kingdom. The huckebein (hkb) gene encodes a conserved SP1/KLF TF known to play important roles in cell cycle regulation, tissue morphogenesis during tubular organ development, and gut specification in Drosophila. …

Examining The Pre-Columbian Use Of Psychotropic Plants In The South American Andes: Tobacco, Coca, And Ayahuasca, Jalayne Allison

Distinguished Undergraduate Researcher Program

This thesis offers a literature review that traces the origins and variations in the use of tobacco (Nicotiana sp.), coca (Erythroxylum coca spp.), and ayahuasca (Banisteriopsis caapi) in the Andean highlands and Amazon region along the western coast of South America. This mountainous region stretches across seven countries: Venezuela, Colombia, Ecuador, Peru, Bolivia, and Argentina. Diverse South American Indigenous groups and ancient civilizations, such as the Inca Empire, have inhabited this area. This review delves into key concepts of Andean cosmology, especially those related to ecology and hydrology as interpreted through Inca beliefs. These concepts are pivotal in the application …

Still A Boy’S Club: Women Journalists & Political News Coverage, Khaleel Oudraogo, Elise Strain

Distinguished Undergraduate Researcher Program

We investigate the level of gender parity in political news reporting at the New York Times. We apply a media sociology approach to examine how gender stereotypes, women in media leadership, and women in political leadership interact to affect the extent to which women journalists appear in bylines about domestic and foreign affairs news. We leverage an original data collection of nearly 3,000 news articles published from 2007–2020. We find several key results. First, women are more likely to appear in bylines about domestic political news than foreign affairs news. Second, we find that during Jill Abramson’s tenure as executive …

Developing A Comparative Framework For Organic Matter Loss Using Standardized Soils To Mimic Urbanized Areas, Madison Woodson, Michael (M.P.) Hayes

Distinguished Undergraduate Researcher Program

Rapid urbanization is an ongoing challenge to the natural ecosystem across Louisiana as the state invests in development to accommodate the challenges of flooding in nearby towns and cities. Across Louisiana waterways, flooding from urban developments along with coastal subsidence and relative sea level rise increase the transport of complex organic matter into local water channels. These events lead to higher concentrations of nutrients, specifically bioavailable carbon which can be lost from breakdown of soil organic matter in water. To better understand and predict organic matter transportation due to flooding events caused by urbanization, we studied the availability of organic …

Semantic Control In The Prefrontal Cortex: An Ale Meta-Analysis, Francesca Thomassee, Christopher Cox

Distinguished Undergraduate Researcher Program

Semantic control is the ability to manage our knowledge about the world to ensure that the information produced is appropriate to a given context (Lamdon Ralph et al., 2017). While the left inferior frontal gyrus (LIFG) has been found to be significantly involved in semantic control (Jackson, 2021), it remains unclear if there is a region of the LIFG that is specific to semantic control and is not involved in any other executive tasks. To investigate this, we employed an activation likelihood estimate (ALE) meta-analysis of prior PET and fMRI research including strong-weak association and feature selection tasks. Based on …

Mtor Signaling And Macrophage Recruitment In Polypterus Senegalus, Icyss Sargeant

Distinguished Undergraduate Researcher Program

Tissue regeneration is marked by significant macrophage activity. Macrophages aid in signaling pathways for tissue growth and differentiation. Salamanders are the only limbed vertebrates capable of complete limb regeneration. However, Polypterus senegalus can fully regenerate its fins after injury. It has been determined that mTOR signaling by macrophages is active in early regeneration. In this project, we will test whether mTOR signaling is necessary for the recruitment of macrophages to regenerate fins in Polypterus senegalus. We began with immunofluorescence of liposomes in tissue sections to quantify macrophages recruited by mTOR signaling in fish treated with DMSO and RAPA. RAPA has …

Feelings And Futures: Social Design Addressing Identity And Engagement Of Adolescent Girls In A Community-Based Organization, Eseoghene Mukoro

Distinguished Undergraduate Researcher Program

Community organizations can provide numerous benefits to adolescent youth in various aspects of their lives—socially, psychologically, and physically, to name a few. Unfortunately, many youth-serving organizations aim to serve youth without directly involving their perspectives in the creation of their respective programs. At the Gardere Initiative, adolescent girls appear to have low levels of engagement and belonging, while their male counterparts enjoy activities and spaces catered to them. This poses a question of how this community organization might better serve the desires and life context of these adolescent girls.
Social Design is the practice of designing an intervention (product, service, …

Memory For Everyday Chores In Younger And Older Adults, Cameron Mccleary, Katie Cherry

Distinguished Undergraduate Researcher Program

This study examined episodic memory performance for everyday household chores in younger (18-32 years) and older adults (65-79 years). With the increasing older adult population in the United States, understanding age-related memory differences and identifying strategies to enhance memory performance in later life is needed. Building on previous research demonstrating the pictorial superiority effect and benefits of semantic encoding across the adult lifespan, this study utilized a 2 × 2 × 2 between-groups factorial design to investigate the effects of age group (younger, older), encoding task (standard intentional learning, semantic elaboration), and stimulus format (text only, text with pictorial illustrations) …

Relearning Language: A Meta-Analysis Of Syntactic Priming In Aphasia, Ally Miller, Willem Van Boxtel

Distinguished Undergraduate Researcher Program

Background: Despite the importance of grammatical skills for participation
in daily life, treatments for sentence–level abilities in aphasia
are comparatively scarce. The psycholinguistic paradigm of syntactic
priming has recently been advanced as a potential assessment and
treatment for grammatical skills, and existing evidence on priming in
aphasia is highly promising. Nevertheless, a comprehensive analysis of
the strength of priming effects in aphasia, as well as treatment components
which might amplify these effects, has not been reported.
This meta–analysis synthesizes existing findings on syntactic priming
in aphasia, aiming to provide a comprehensive picture of priming
effects and their potential application for …

Motor Planning And Execution During Feeding In Autistic Children, Iresa Lincoln

Distinguished Undergraduate Researcher Program

Autism is one of the most common pediatric developmental disability diagnoses, diagnosed in approximately 1 in 31 children in the U.S. and 1 in 100 children globally. Autism is often characterized by differences in social communication and repetitive patterns of behavior, activities,
or interests; however, prevalence of clinically significant motor differences in autistic individuals is between 50-95%. These motor differences often interfere with activities of daily living and community participation. Research assessing motor control in autism has yielded mixed findings as to whether the motor differences observed in autistic individuals are associated with differences in motor planning or motor execution. …

Bridging Distances: Exploring Teleoperation’S Present And Prospects In The Construction Industry, Marc Hebert, Aras Maqsoodi, Ali Kazemian

Distinguished Undergraduate Researcher Program

Telerobotics has enabled major advancements and developments in multiple fields by providing safer robotic solutions. The construction industry has previously employed teleoperation, but its use has been limited in scope and primarily focused on earthwork. Teleoperation is a valuable tool for ensuring safe operations in extreme environments and inaccessible areas, enabling construction workers to remotely oversee tasks that are traditionally high-risk. Recent advancements in high-speed telecommunication networks, innovative control systems, and growing research in teleoperation have significant potential and practicality for application in the construction industry. This paper reviews the existing literature on construction teleoperation, emphasizing how advancements in Human-Machine …

Measuring The Rise And Fall Of Plasma 25-Hydroxyvitamin D Concentrations In Blue-Tongued Skinks (Tiliqua Scincoides) Following Ultraviolet B Exposure And Withdrawal, Ashleigh Godke, Haerin Rhim, M. Graciela Aguilar, Keishla Marrero-Acosta, Mark Mitchell

Distinguished Undergraduate Researcher Program

Species-specific husbandry guidelines remain limited for blue-tongued skinks (Tiliqua scincoides), especially in relation to ultraviolet B (UVB) lighting and vitamin D requirements. This study aimed to determine whether UVB exposure is necessary for these skinks and how long 25-hydroxyvitamin D (25-OHD) concentrations persist after UVB withdrawal. Eleven adult skinks who had been fed with wet cat food were exposed to 12 or 2 h of UVB per day for four weeks. Plasma 25-OHD concentrations were very low at the baseline, and significantly increased post-UVB in both groups (p < 0.01), with the 12-hour group increasing from baseline concentrations of 18.5 [12.8–20.5] nmol/L to 820 [730–1251.3] nmol/L and the 2-hour group increasing from baseline concentrations of 22 [15.5–22] nmol/L to 635 [401–892.5] nmol/L. Following the discontinuation of UVB exposure, 25-OHD gradually declined and was not significantly different from baseline concentrations at 7 and 4 months for the 12-hour and 2-hour groups, respectively. Dietary vitamin D3 (2.5 IU/g as dry matter basis), provided through wet cat food alone, appeared insufficient to support sustained plasma 25-OHD concentrations. These findings strongly suggest that blue-tongued skinks rely on UVB exposure to increase their 25-OHD concentrations. Moreover, the shorter 2-hour exposure provided a significant rise in 25-OHD concentrations and remained above baseline for 4 months, suggesting the shorter exposure can benefit these animals, while potentially reducing secondary risks associated with UVB exposure.

Analyzing And Understanding America’S Involvement In The Global War In Terror Through The Oral Histories Of Its Veterans And Other Sources, Bryce Edwards

Distinguished Undergraduate Researcher Program

From 2001 to the early 2020s, the United States and its allies have consistently engaged in political, military, counterinsurgency, and nation building operations in nations such as Afghanistan and Iraq. The efforts of this coalition first rallied to combat the threat of global terrorism after September 11th, yet it would then develop in decades-long assignment to rebuild these countries and their institutions with fundamental (and foreign) western values. This thesis intends to examine the conflict by conducting oral histories of its many veterans, to better understand their lived experience. These interviews will be supported by scholarly works from those involved …

Gullah Geechee, Progenitors For African North American Maternal Lineage, Jennifer Caldwell, Imani Sykes, Robbie Beyl, Tomilowo Abijo, Kiara Charles, Fatimah Jackson

Distinguished Undergraduate Researcher Program

African American ancestral lineages are marked by resilience, shaped by centuries of forced migrations, the Transatlantic and domestic slave trades, and subsequent movements within the United States. These historical events have influenced both the cultural and genetic diversity of Legacy African Americans. This study examined mitochondrial DNA (mtDNA) haplogroups among 189 participants—79 Gullah Geechee and 110 African Americans—to explore the Gullah Geechee as potential progenitors of other Legacy African North American lineages. Haplogroup analysis revealed L2 and L3 as the most frequent among both groups, comprising 34.6% and 38.8% in African Americans and 28.0% and 54.7% in Gullah Geechee, respectively. …

Droplet Microfluidics Integrated With Machine Learning Reveals How Adipose-Derived Stem Cells Modulate Endocrine Response And Tumor Heterogeneity In Er+ Breast Cancer, Calley Chauvin, Braulio Andres Ortega Quesada, Elizabeth Martin, Adam Melvin

Distinguished Undergraduate Researcher Program

Approximately 70% of breast cancer (BC) diagnoses are estrogen receptor positive (ER+) with ∼40% of ER+ BC patients presenting de novo resistance to endocrine therapy (ET). Recent studies identify the tumor microenvironment (TME) as having a key role in endocrine resistance in which adipose-derived stem cells (ASCs) play an essential role in cancer progression. Prior studies have indicated that ASC characteristics such as age and BMI may play a role in cancer progression. Unfortunately, most studies on ASC-BC cross talk have relied on established two-dimensional (2D) culture systems or the use of conditioned media that cannot replicate the complexity of …

Quantifying Uncertainty In Landscape Evolution And Provenance Analysis: Insights From Statistical And Numerical Modelling, Vivian Carmello Grom

LSU Doctoral Dissertations

Landscape evolution models (LEMs) and detrital zircon provenance are widely used to investigate Earth surface processes, yet both face challenges related to quantifying model behavior and interpreting sedimentary signals under realistic, heterogeneous conditions. This thesis addresses these challenges through analysis and case studies that develop and apply new approaches for analyzing landscape dynamics and assessing uncertainties in sediment provenance.

Chapter 1 introduces a quantitative framework for evaluating LEM outputs using Shannon Entropy, Moran’s I, and Geary’s C. Applied to simulations with steady uplift, periodic uplift, spatially variable uplift, and a timeseries of DEMs, these metrics capture spatial organization and information …

Satellite-Mediated Quantum Clock Synchronization: Towards Precise Timing At A Global Scale, Sage B. Ducoing

LSU Doctoral Dissertations

Accurate timekeeping is essential for scientific and technological advancements, particularly in areas of communication, networking, navigation, and high precision measurements. While many methods of time resolution are already established using classical resources, they fail to combine high precision outcomes with large-scale implementations. Additionally, numerous quantum networking architectures using satellite-assisted methods have demonstrated quantum communication on scales exceeding ground-based methods. For these reasons, we propose the use of a time synchronization method by which pairs of highly time-correlated photons are exchanged between clocks on satellites and clocks on Earth, al- lowing users to reconstruct the time offsets between their clocks. This …

Cache-Conscious Sparse Matrix Dense Matrix Multiplication On Gpus, Haoqiang Guo

LSU Doctoral Dissertations

Over the past decade, high-performance deep learning has evolved into a critical research domain, driven by the demand for efficient models and high inference throughput. Deep learning architectures have shifted from stacked convolutional layers to transformer-based models, while pruning techniques and graph-structured data have established sparse matrix–dense matrix multiplication (SpMM) as a fundamental kernel—particularly in graph neural networks (GNNs). Modern GPUs, with their massive parallelism and high-bandwidth memory, offer immense potential for accelerating these workloads. While SpMM implementations using the compressed sparse row (CSR) format remain common to avoid conversion overhead, preprocessing-based methods have recently demonstrated superior potential. In GNN …

Role Of Cellular Stress Responses In Innate Immune Defense Against Acute Respiratory Infections, Amit Sharma

LSU Doctoral Dissertations

The endoplasmic reticulum (ER) stress sensor inositol-requiring enzyme 1α (IRE1α) is an important regulator of innate immune cells. However, its role in pulmonary innate host defenses remains poorly understood. This dissertation elucidates the dual, context-dependent role of IRE1α in host defense against methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. We demonstrate IRE1α’s function as both a detrimental mediator of acute pathology and an essential facilitator of innate immune memory. Our work revealed that acute IRE1α activation during primary MRSA infection is detrimental. In lungs and alveolar macrophages (AMs), IRE1α is activated in response to MRSA infection. Consequently, IRE1α activation triggers a hyperinflammatory …

From Storage Closet To Creative Oasis: How To Set Up An Atelier And Outdoor Space For Young Children, Catherine Lynch, Cynthia Dicarlo

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

Creating meaningful learning spaces doesn't always require a big budget or new construction—sometimes, all it takes is a storage closet, a bit of imagination, and a deep respect for children’s ideas. In this article, I’ll share how we transformed underutilized spaces at our school into a vibrant atelier and outdoor classroom and offer tips to help you do the same.

Supporting Best Practices In Family Engagement: Our Week Of The Young Child Experience, Michelle Fazio Brunson, Faith S. Birdwell, April Giddens

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

Family engagement is a collaborative process where early childhood professionals, families, and children build positive, goal-oriented relationships. Incorporating family engagement into preschool programs is not merely beneficial but essential for promoting holistic child development in programs where children feel safe, cared for, and secure. In this article, we share the benefits of effective family engagement activities for families with young children and describe how we celebrated the National Association for the Education of Young Children's 2025 Week of the Young Child.

Understanding And Supporting Sustained Attention In Young Children: What Research Tells Us About Choice, Play, And Teaching Conditions, Cynthia F. Dicarlo, Carrie L. Ota

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

This article examines how sustained attention develops in young children and how different teaching conditions influence engagement during play. Drawing on studies with two-, three-, and four-year-olds, the findings show a developmental progression in which toddlers benefit from limited, adult-guided choices, while preschoolers sustain attention best when given autonomy to select their own materials. The article highlights how play, intentional choice-making, and age-appropriate scaffolding support children’s emerging self-regulation and engagement. Practical strategies are provided to help teachers design environments and interactions that promote deeper focus and independent learning.

Using Food As A Fun And Effective Teaching Tool In Preschool, Kelly Furr, Melani Duffrin, Eugene A. Geist

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

Food is one of the most engaging, hands-on materials for preschool classrooms. This article highlights research from the Food FAN Academy (Furr, 2023), which demonstrates how food can be used as a teaching tool across early childhood learning environments. Practical strategies are provided for preschool teachers, including detailed lesson plans that connect to early math, science, literacy, and social development. The article emphasizes the importance of using everyday materials, cultural inclusivity, and active learning methods to promote curiosity, health awareness, and foundational skills in young learners.

Abcs Of Behavior: Strategies To Effectively Reduce Challenging Behaviors, Sarah Matthews

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

This paper explores the application of the ABC (Antecedent-Behavior-Consequence) model and functional behavior assessments (FBAs) to understand and manage challenging behaviors in early childhood education settings. Grounded in developmental theory and informed by professional experience as an early interventionist, the paper emphasizes the importance of identifying behavioral triggers and using individualized, developmentally appropriate strategies. The role of collaboration among teachers, families, and specialists is highlighted as essential for consistent and effective intervention. Key strategies discussed include coaching caregivers, embedding interventions within natural classroom environments, and using positive, non-punitive approaches to time-out. The paper advocates for proactive, respectful behavioral guidance practices …

Equity-Aware Natural Hazards Resilience Assessment And Improvement Of Road Networks, Naqib Mashrur

LSU Doctoral Dissertations

As climate change intensifies the frequency and severity of hurricanes, the resulting flood events pose escalating threats to transportation infrastructure and community well-being. This dissertation addresses the intersection of flood resilience, network connectivity, and social equity by integrating principles from network analysis, equity planning, and disaster resilience. The research begins by examining the social dimensions of accessibility loss during hurricane-induced flooding. Spatial and demographic analysis reveals that Native American and Hispanic populations in the case study region experience the most significant reductions in access to essential service facilities, highlighting inequities in systems.

Investigating a region southern Louisiana road network demonstrates …

Bridging Modalities: Enhancing Multimodal Sentiment Analysis For Social Media Networks, Misbah Ul Hoque

LSU Doctoral Dissertations

Social media platforms like X (formerly Twitter) serve as rich sources of textual and visual information, making multimodal sentiment analysis essential for understanding complex human emotions. This dissertation aims to advance multimodal sentiment analysis by improving the semantic alignment and fusion of textual and visual features, thereby enabling more accurate and context-aware sentiment interpretation of social media content.

To address challenges in multimodal integration, this work proposes two complementary MSA approaches. The first approach introduces a similarity-based multi-layer attention neural network (SiMANN) that enhances modality integration through cosine-based similarity fusion and modality-specific attention to emphasize salient features in text and …

Rapid Microbial Activity In Marine Sediments Significantly Enhances Silica Cycling Rates Compared To Abiotic Processes, Panagiotis Michalopoulos, Jeffrey W. Krause, Rebecca A. Pickering, Eleni Rousselaki, Kanchan Maiti, Martial Taillefert, Christophe Rabouille, Rudolph Corvaisier

Faculty Publications

Silicon, earth’s second most abundant element, cycles via biogeochemical processes in terrestrial and oceanic environments. The marine sediment-water interface is thought to divide biological-dominated (water) from abiotic-dominated (sediment) silica cycling processes. Studies indicate marine extremophile bacteria induce silica precipitation, but the quantitative importance of microorganisms in broader sediment silica cycling remains unexplored. We hypothesize that microorganisms significantly influence sediment silica cycling, challenging the prevailing divide of microbial importance. Within hours, sediment microbes expedited silica sequestration through rapid coupled dissolution/reprecipitation processes in marine deltaic sediment experiments. Using radiotracer silicon-32, we reveal that microbial mediation enhanced silica uptake, surpassing abiotic uptake by …

Elucidating The Role Of Marine Benthic Carbon In A Changing World, Cristina Schultz, Jessica Y. Luo, Damian C. Brady, Robinson W. Fulweiler, Matthew H. Long, Colleen M. Petrik, Jeremy M. Testa, Heather M. Benway, David Burdige, Marta M. Cecchetto, Isa Elegbede, Natalya Evans, Alexandra Frenzel, Kayla Gillen, Lisa C. Herbert, Heidi K. Hirsh, Gennadi Lessin, Lisa Levin, Kanchan Maiti, Sairah Malkin, Sarah L. Mincks, Stanley Nmor, Anh Pham, James Pinckney, Christophe Rabouille, Shaily Rahman, Subhadeep Rakshit, Nicholas E. Ray, Dalton K. Sasaki, Samantha A. Siedlecki, Christopher Somes, Aron Stubbins, Olivier Sulpis

Faculty Publications

The ocean plays a major role in controlling atmospheric carbon at decadal to millennial timescales, with benthic carbon representing the only geologic-scale storage of oceanic carbon. Despite its importance, detailed benthic ocean observations are limited and representation of the benthic carbon cycle in ocean and Earth system models (ESMs) is mostly empirical with little prognostic capacity, which hinders our ability to properly understand the long-term evolution of the carbon cycle and climate change-related feedbacks. The Benthic Ecosystem and Carbon Synthesis (BECS) working group, with the support of the US Ocean Carbon & Biogeochemistry Program (OCB), identified key challenges limiting our …

Hurricanes And Human Health In Louisiana: Insights From Hurricanes Laura, Delta, And Ida, Shobha Kumari Yadav, Robert V. Rohli, M. E. Betsy Garrison, Elisabeth Ponce-Garcia, Nazla Bushra, Charleen Mcneill

Faculty Publications

Louisiana is one of the most disaster-prone states, with hurricanes ranking among the most destructive hazards. Hurricanes impede sustainability by straining hospital infrastructure, overwhelming emergency departments, and disrupting continuity of care. Louisiana’s healthcare system, characterized by high uninsured rates, limited rural access, and notable racial and socioeconomic disparities, is particularly vulnerable during disasters. This research explores trends of mental and respiratory health in Louisiana surrounding Hurricanes Laura (2020), Delta (2020), and Ida (2021). Analysis reveals a substantial increase in admissions after landfall of all three storms, with mental health conditions showing a larger surge than respiratory ones in already-vulnerable communities. …

Contrasting Climate Oscillations Impacts On Phytoplankton In The Western And Eastern Tropical Pacific, Lina An, Edward A. Laws, Xin Liu, Ruiying Chen, Shanlin Wang, Shijian Hu, Yuchen Zhang, Yibin Huang, Feipeng Xu, Fei Chai, Bangqin Huang

Faculty Publications

Climate oscillations like the El Niño-Southern Oscillation and Pacific Decadal Oscillation significantly impact marine ecosystems. Traditionally, warm events are thought to suppress nutrient availability, reduce phytoplankton biomass, and change community structure. However, using two decades of field observations, remote sensing, Copernicus reanalysis, and Earth system modeling, we find very different responses in the western tropical Pacific. During El Niño, chlorophyll concentrations and diatom contributions increase, while La Niña reverses that trend. The further amplification of these El Niño-Southern Oscillation-driven contrasts by the Pacific Decadal Oscillation can be attributed to its effects on regional circulation, including the enhancement of eddy activity …