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Structure-Activity Relationships Of Nitroarenes: Mutagenicity, Oxygen Consumption, Toxicity, And Xenobiotic Radical Production., Caroline Ann Metosh-Dickey Jan 1997

Structure-Activity Relationships Of Nitroarenes: Mutagenicity, Oxygen Consumption, Toxicity, And Xenobiotic Radical Production., Caroline Ann Metosh-Dickey

LSU Historical Dissertations and Theses

The nitroreduction of 4NQO and five structural analogs were studied with respect to radical production and mutagenicity. In the umu assay, 4NQO was the most mutagenic analog. Addition of microsomal and cytosolic protein from induced and uninduced rat liver samples decreased 4NQO mutagenicity in the standard strain (Salmonella typhimurium TA 1535/psk1002) 4NQO mutagenicity was also found to be decreased in the nitroreductase-deficient strain (Salmonella typhimurium TA1535NR/psk1002). In several strains of the Protox$\rm\sp{TM}$ assay 4NQO yielded the highest induction rate as compared to other compounds tested. In the presence of ascorbate 4NQO cytotoxicity, but not mutagenicity, was substantially enhanced. Oxygen consumption …

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Nature, Culture And Big Old Trees: Human Relationships With Ceiba (Ceiba Pentandra) And Live Oak (Quercus Virginiana) In The Landscapes Of Guatemala And Louisiana., Katharine Anderson Jan 1997

Nature, Culture And Big Old Trees: Human Relationships With Ceiba (Ceiba Pentandra) And Live Oak (Quercus Virginiana) In The Landscapes Of Guatemala And Louisiana., Katharine Anderson

LSU Historical Dissertations and Theses

The ceiba in Guatemala and the live oak in Louisiana are examples of two trees that attain great size and age within the cultural landscape. Humans have adopted both as symbolic trees; they protect, encourage and even plant them. As the trees age, they become historic landmarks, are indicators of important places, and give character to the landscape. Although each tree is native within portions of each study area, both have taken advantage of human disturbance to expand beyond their original habitats. In addition, they have been moved deliberately by humans to new areas well beyond their geographical limits. Other …

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Development And In Vivo Evaluation Of A Pura Mutant Strain Of The Channel Catfish Pathogen Edwardsiella Ictaluri., Mark Lee Lawrence Jan 1997

Development And In Vivo Evaluation Of A Pura Mutant Strain Of The Channel Catfish Pathogen Edwardsiella Ictaluri., Mark Lee Lawrence

LSU Historical Dissertations and Theses

Edwardsiella ictaluri is the causative agent of enteric septicemia of catfish (ESC), which is the most serious disease affecting the channel catfish industry. Killed vaccines have been inconsistent in providing protection against ESC, and no live attenuated vaccines have been described. The purpose of this study was to develop a nutritionally attenuated mutant strain of E. ictaluri and evaluate its virulence and vaccine efficacy. An E. ictaluri genomic library was constructed, and a clone containing the purA gene was isolated and sequenced. The E. ictaluri purA gene was found to have several features in common with the E. coli purA …

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Moved By The Spirit: Protestant Diffusion And Church Location In Central America, With A Case Study From Southwestern Honduras., Terri Shawn Mitchell Jan 1997

Moved By The Spirit: Protestant Diffusion And Church Location In Central America, With A Case Study From Southwestern Honduras., Terri Shawn Mitchell

LSU Historical Dissertations and Theses

This dissertation traces the evolution of Protestant missions in Central America from the colonial period to the present, focusing on the agents, direction, and methods of Protestant diffusion as well as the changing criteria for site selection. Chapters are arranged chronologically and progress from the macro-scale, Central America, to the micro-scale, six towns in southwestern Honduras (La Esperanza, Intibuca, Yamaranguila, San Juan, Erandique and Gracias). The chapters dealing with Central America outline when and where different mission boards have worked, as well as the geographical, economic, political and theological considerations driving site selection. The focus then narrows to patterns of …

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Caprine Sperm Cells As Vectors For Gene Transfer., Yongxin Sun Jan 1997

Caprine Sperm Cells As Vectors For Gene Transfer., Yongxin Sun

LSU Historical Dissertations and Theses

Goat sperm cells were used as a model to evaluate sperm-mediated gene transfer. Fresh and frozen-thawed goat sperm cells were co-incubated with radio-labelled foreign DNA. After 10 extensive washings, the compacted sperm retained foreign DNA. Confocal microscopy confirmed that the position on the sperm cell responsible for binding of foreign DNA was located in both the anterior and the posterior heads of caprine sperm cells. Furthermore, confocal longitudinal sections of the sperm cells showed that foreign DNA had penetrated into goat sperm nuclei. In this study, 37% of the fresh goat sperm and 33% of the frozen-thawed goat sperm cells …

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Acid Solubilization Of Fish Protein For Production Of Protein Hydrolysate., Ercument Ozer Jan 1997

Acid Solubilization Of Fish Protein For Production Of Protein Hydrolysate., Ercument Ozer

LSU Historical Dissertations and Theses

The mechanism of fish protein solubilization by acid hydrolysis at elevated temperatures was investigated. Rate expressions for the solubilization were determined using pilot scale data with two different rate determination methods. A postulated mechanism was verified and estimated rates were evaluated on five independent verification experiments. A functional relationship between nonprotein byproduct concentration and whiteness of fish protein hydrolysate (FPH) was developed. Initial and set-point operating variables were calculated to produce FPH with acceptable color characteristics for food use. A batch reactor was used for duplicate hydrolysis trials conducted at three acid and three temperature levels for four hours. Samples …

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Ephemeral Hinterlands And The Historical Geography Of Trujillo, Honduras, 1525-1950., Taylor E. Mack Jan 1997

Ephemeral Hinterlands And The Historical Geography Of Trujillo, Honduras, 1525-1950., Taylor E. Mack

LSU Historical Dissertations and Theses

The historical geography of Trujillo, Honduras is told through its changing hinterlands. This dissertation uses world systems to approach and understand the historical geography of Trujillo, however, the focus is on this peripheral area of the world system, rather than on the core. The coast of the western Caribbean experiences economic boom and bust cycles. The periodization of Trujillo's historical geography is based on the city's boom and bust periods, using primary documents from archives in Central America and Spain. Trujillo's first boom period lasted from its founding in 1525 until 1550, based on gold exports from the interior. During …

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The Prism Of Laughter: Antebellum Humorists In Regional Perspective., Henry O. Robertson Jr Jan 1997

The Prism Of Laughter: Antebellum Humorists In Regional Perspective., Henry O. Robertson Jr

LSU Historical Dissertations and Theses

This work revises earlier interpretations of antebellum American humorists and sets forth a new model for understanding their accomplishments. Rooted in historical thinking, this study integrated biography, publishing history, critical responses, and a penetrating analysis of the sketches of several major figures. The first third examined Seba Smith, Joseph C. Neal, and Augustus Baldwin Longstreet. A devotion to their communities in Maine, Philadelphia, and Georgia, respectively, and preference for writing warm, genial selections remained important shared influences while cultural differences between the societies in which each matured and wrote made their humor diverge significantly. In both content and expression their …

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The Effects Of Homogenized Cream And Commercial Buttermilk Powder On Low-Fat Cheddar Cheese., Tonya Conner Schoenfuss Jan 1997

The Effects Of Homogenized Cream And Commercial Buttermilk Powder On Low-Fat Cheddar Cheese., Tonya Conner Schoenfuss

LSU Historical Dissertations and Theses

Seventy percent reduced fat Cheddar cheese was manufactured with homogenized cream and sweet cream buttermilk powder in an effort to improve flavor and texture characteristics. Manufacturing procedures, as well as the chemical, physical and sensory attributes. Pasteurized cream was homogenized (15.8 MPa) with and without the addition of buttermilk powder. The cream was added to pasteurized skim milk to produce two vats of cheese, one with and one without buttermilk powder. After milling, each vat was split to produce a washed curd and normal curd cheese. The four cheeses were sampled at week one, and months one, two and four. …

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Relative Rates Of Molecular Evolution In Rodents And Their Symbionts., Theresa Ann Spradling Jan 1997

Relative Rates Of Molecular Evolution In Rodents And Their Symbionts., Theresa Ann Spradling

LSU Historical Dissertations and Theses

The focus of this dissertation is the relative tempo of molecular evolution among organisms of varying levels of relatedness. Because this is a rapidly expanding area of research, Chapter 1 is devoted to a review of the current state of knowledge on rates of molecular evolution. In Chapter 2, I present an analysis of relative rates of evolution among several distantly related rodents. The heterogeneity in rate of evolution of the cytochrome b gene observed here cannot be explained by metabolic rate, body size, generation time, or nucleotide-generation time. Likewise, there is no evidence that these differences in rate of …

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Indigenous Lands In A Developing Region: A Historical Ethnogeography Of The Pech Indians Of Eastern Honduras, With Emphasis On Recent Settlement And Land Use Changes., James Richard Samson Jan 1997

Indigenous Lands In A Developing Region: A Historical Ethnogeography Of The Pech Indians Of Eastern Honduras, With Emphasis On Recent Settlement And Land Use Changes., James Richard Samson

LSU Historical Dissertations and Theses

Since before Spanish Contact, the Pech Indians have occupied a large portion of northeastern Honduras. Like other native American populations, they have suffered significant territorial reductions and cultural alterations at the hands of European colonists and modern ladino immigrants. Utilizing the methodologies of cultural geography, ethnohistory, and ethnogeography, the Pech, formerly known as the Paya, are scrutinized to illustrate the process by which indigenous peoples are reduced and incorporated into a developing national setting. Part One examines the scholarly record on the ethnohistory of the Pech and their neighbors to delimit their habitats and to document Pech incorporation into the …

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Cloning And Expression Of Capsid Proteins Of Hepatitis A Virus In Escherichia Coli., Lingaiah Chandrashekar Jan 1997

Cloning And Expression Of Capsid Proteins Of Hepatitis A Virus In Escherichia Coli., Lingaiah Chandrashekar

LSU Historical Dissertations and Theses

Hepatitis A virus (HAV), the causative agent of food and water borne acute hepatitis worldwide, is very difficult and expensive to propagate in tissue culture. Large scale production of HAV proteins in E. coli by recombinant DNA techniques would be invaluable for antisera production, biochemical analyses and in developing sensitive diagnostic tests. Therefore, PCR amplified DNA fragments encoding the HAV capsid proteins were cloned individually into prokaryotic expression vectors for production of either recombinant fusion or non-fusion proteins. Cloning and expression of HAV capsid genes, which induced toxic effects in certain host E. coli, was tolerated better by protease-deficient host …

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Amino Acid Requirements And Crystalline Amino Acids For Finishing Pigs., Theresia Alice Knowles Jan 1997

Amino Acid Requirements And Crystalline Amino Acids For Finishing Pigs., Theresia Alice Knowles

LSU Historical Dissertations and Theses

This research was conducted to obtain a better understanding of the amino acid needs of finishing pigs. Twelve experiments were conducted using the urea nitrogen method to determine the lysine requirement of gilts and barrows. Two experiments were conducted to determine the optimum ratio of total sulfur amino acids to lysine for finishing pigs (74 to 111 kg); and three experiments were conducted to evaluate the net energy content of low crude protein, crystalline amino acid supplemented diets for finishing pigs (70 to 117 kg). The lysine requirement of gilts, as determined by the urea nitrogen method, decreased as body …

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Characterization Of The Cytochromes P450-Dependent Hepatic Microsomal Monooxygenase System Of The American Alligator, Alligator Mississippiensis: Influence Of Xenobiotic Chemicals., Robin Parsons Ertl Jan 1997

Characterization Of The Cytochromes P450-Dependent Hepatic Microsomal Monooxygenase System Of The American Alligator, Alligator Mississippiensis: Influence Of Xenobiotic Chemicals., Robin Parsons Ertl

LSU Historical Dissertations and Theses

Alligator mississippiensis contains all of the components of the hepatic microsomal mixed function oxidase system. In general, basal and induced levels of P450 specific content, immunochemically detected abundance and examined activities are less than in mammals. In alligator at least two classes of P450s are inducible by xenobiotics: those induced by 3-methylcholanthrene (3MC) and those induced by phenobarbital (PB). PB and 3MC induce multiple P450 isoforms as detected by western blot and enzymatic analyses. The induced level of alkoxyphenoxazone O-dealkylation (AROD) was 10- to 100-fold lower in alligator than in rat, with the exception of phenylbenzyloxyphenoxazone O-dealkylation. In contrast to …

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Identification And Quantification Of S-(2-(N(7)-Guanyl)Ethyl)Glutathione Dna Adduct In Channel Catfish (Ictalurus Punctatus) After Exposure To 1,2-Dichloroethane., Ahmedin Muktar Jemal Jan 1997

Identification And Quantification Of S-(2-(N(7)-Guanyl)Ethyl)Glutathione Dna Adduct In Channel Catfish (Ictalurus Punctatus) After Exposure To 1,2-Dichloroethane., Ahmedin Muktar Jemal

LSU Historical Dissertations and Theses

The main goal of the study was to provide the basic technical frame work for the use of native fish species as environmental sentinels for potential human exposure to genotoxic agents in general and to 1,2-dichloroethane (ethylene dichloride) in particular. First, LC/MS/ESI/ID and LC/MS/MS/ESI/ID methods for detection and quantification of S- (2-(N$\sp7$-guanyl)ethyl) glutathione DNA adduct from biological samples was developed. The methods were tested by exposing groups of rats with three dose levels of 1,2-dibromoethane. They allowed detection of $\sim$1 adduct in 10$\sp7$ bases. Second, the formation and persistence of DNA adduct in channel catfish (Ictalurus punctatus) from 1,2-dichloroethane exposure …

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Pest Status And Management Of Beet Armyworm, Spodoptera Exigua (Hubner), On Cotton In Louisiana., Victor James Mascarenhas Jan 1997

Pest Status And Management Of Beet Armyworm, Spodoptera Exigua (Hubner), On Cotton In Louisiana., Victor James Mascarenhas

LSU Historical Dissertations and Theses

Field cage studies were conducted to measure the effects of late season beet armyworm, Spodoptera exigua (Hubner), infestations (0, 1, 3, and 6 egg masses per 5.1 row m) on defoliation, fruit damage, and yield of cotton. Light penetration through the canopy was significantly higher in infested plots. Although a trend for increased numbers of damaged fruiting forms with increases in egg mass density was observed, there were no significant differences between infested and control plots. There were no significant differences in the cumulative number of shed fruiting forms or yield between infested and control plots. Field tests were conducted …

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Metamorphosis Of The Hawaiian Stream Goby Sicyopterus Stimpsoni: A Structural, Functional, And Behavioral Analysis., Heiko Lars Schoenfuss Jan 1997

Metamorphosis Of The Hawaiian Stream Goby Sicyopterus Stimpsoni: A Structural, Functional, And Behavioral Analysis., Heiko Lars Schoenfuss

LSU Historical Dissertations and Theses

The endemic goby Sicyopterus stimpsoni is unique among five species of Hawaiian freshwater fishes because it undergoes rapid metamorphosis of cranial structures during postlarval development. These fishes are amphidromous and return after a prolonged stay in the ocean to streams where they are confined to estuaries until completion of cranial restructuring. Within 48 hours after entering fresh water, head width increases significantly, while total length and head length remains unchanged. Weight decreases by approximately 15% during this period. The upper lip enlarges greatly, and the mouth position shifts from terminal to nearly ventral. Shape analysis of radiographs taken from a …

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Aerenchyma Development In The Freshwater Marsh Species Sagittaria Lancifolia L., Elisabeth Ellen Schussler Jan 1997

Aerenchyma Development In The Freshwater Marsh Species Sagittaria Lancifolia L., Elisabeth Ellen Schussler

LSU Historical Dissertations and Theses

Aerenchyma tissue consists of gas channels that provide a pathway for O$\sb2$ transport to waterlogged roots. Aerenchyma gas spaces are formed by cell separation or cell lysis during development. Light microscopy was used to determine how aerenchyma develops in Sagittaria lancifolia, a freshwater marsh species, when plants were grown in hydroponic solution. Petiole aerenchyma was formed by cell separation caused by differential cell expansion and division. In the root cortex, certain radial files of cells separated slightly from adjacent files and then lysed to form gas spaces. Development of root aerenchyma was characterized in S. lancifolia, Zea mays, and Oryza …

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Lectin Binding Affinities Of Egg Coats And Sperm Of The Freshwater Zebra Mussel, Dreissena Polymorpha, Kathryn Margaret Kreimborg Jan 1997

Lectin Binding Affinities Of Egg Coats And Sperm Of The Freshwater Zebra Mussel, Dreissena Polymorpha, Kathryn Margaret Kreimborg

Honors Capstones

No abstract provided.

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Louisiana Agriculture Magazine, Winter 1997, Lsu Agricultural Experiment Station Jan 1997

Louisiana Agriculture Magazine, Winter 1997, Lsu Agricultural Experiment Station

Louisiana Agriculture

No abstract provided.

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Lsu General Catalog 1997-1998, Louisiana State University And Agricultural And Mechanical College Jan 1997

Lsu General Catalog 1997-1998, Louisiana State University And Agricultural And Mechanical College

LSU General Catalog

The LSU General Catalog describes all undergraduate and graduate departments and programs with degree requirements and courses offered for each one. The General Catalog includes information on registration and financial aid as well as academic services offered to all students.

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Front Matter Jan 1997

Front Matter

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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The Shortest Way To Heaven? Moll Flanders' Prepentance Reconsidered, Michael F. Suarez S.J. Jan 1997

The Shortest Way To Heaven? Moll Flanders' Prepentance Reconsidered, Michael F. Suarez S.J.

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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Breaking The Shackles Of The Great Chain Of Being And Liberating Compassion In The Eighteenth Century, Katherine Kerestman Jan 1997

Breaking The Shackles Of The Great Chain Of Being And Liberating Compassion In The Eighteenth Century, Katherine Kerestman

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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The Author As Ghost In The Eighteenth Century, Laura J. Rosenthal Jan 1997

The Author As Ghost In The Eighteenth Century, Laura J. Rosenthal

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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The Transmission Of German Literature And Dissenting Voices In British Culture Thomas Holcroft And The Godwin Circle, Gregory Maertz Jan 1997

The Transmission Of German Literature And Dissenting Voices In British Culture Thomas Holcroft And The Godwin Circle, Gregory Maertz

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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Matching The "Matchless Orinda" To Her Times, Kathleen M. Swaim Jan 1997

Matching The "Matchless Orinda" To Her Times, Kathleen M. Swaim

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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Robert Browning's "In A Gondola" Sources And Circumstances, Murray L. Brown Jan 1997

Robert Browning's "In A Gondola" Sources And Circumstances, Murray L. Brown

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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The Terrible Mother Archetype The Case Of Pope's Dulness And Other Women In Eighteenth-Century Texts, Carl R. Kropf Jan 1997

The Terrible Mother Archetype The Case Of Pope's Dulness And Other Women In Eighteenth-Century Texts, Carl R. Kropf

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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Book Review Corner, Anna Battigelli Jan 1997

Book Review Corner, Anna Battigelli

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.

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