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Selection Of Breeding Stock By U.S. Meat Goat Producers, Narayan Nyaupane, Jeffrey Gillespie, Kenneth Mcmillin, Robert Harrison, Isaac Sitienei Aug 2017

Selection Of Breeding Stock By U.S. Meat Goat Producers, Narayan Nyaupane, Jeffrey Gillespie, Kenneth Mcmillin, Robert Harrison, Isaac Sitienei

Faculty Publications

© 2017 The Author(s). Using nationwide survey data, we investigate U.S. meat goat producer preferences and willingness to pay for meat goat breeding stock attributes. Discrete choice experiments were employed, and mixed logit and latent class models were used for analysis. Results showed that producers preferred animals that were highly masculine/feminine, had good structure and soundness, and were of the Boer breed, whereas they preferred fewer animals that were older, of Kiko and Spanish breeds, and priced higher. Significant preference heterogeneity was found among the respondents. Larger-scale producers had greater preference for high masculinity/femininity, good structure and soundness, and Boer …

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Retinoic Acid Inhibits White Adipogenesis By Disrupting Gadd45a-Mediated Zfp423 Dna Demethylation, Bo Wang, Xing Fu, Mei Jun Zhu, Min Du Aug 2017

Retinoic Acid Inhibits White Adipogenesis By Disrupting Gadd45a-Mediated Zfp423 Dna Demethylation, Bo Wang, Xing Fu, Mei Jun Zhu, Min Du

Faculty Publications

© The Author (2017). Retinoic acid (RA), a bioactive metabolite of Vitamin A, is a critical mediator of cell differentiation. RA blocks adipogenesis, but mechanisms remain to be established. ZFP423 is a key transcription factor maintaining white adipose identity. We found that RA inhibits Zfp423 expression and adipogenesis via blocking DNA demethylation in the promoter of Zfp423, a process mediated by growth arrest and DNA-damage-inducible protein alpha (GADD45A). RA induces the partnering between retinoic acid receptor (RAR) and tumor suppressor inhibitor of growth protein 1 (ING1), which prevents the formation of GADD45A and ING1 complex necessary for locus-specific Zfp423 DNA …

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Structural And Mutational Analyses Of The Leptospira Interrogans Virulence-Related Heme Oxygenase Provide Insights Into Its Catalytic Mechanism, Anabel Soldano, Sebastián Klinke, Lisandro H. Otero, Mario Rivera, Daniela L. Catalano-Dupuy, Eduardo A. Ceccarelli Aug 2017

Structural And Mutational Analyses Of The Leptospira Interrogans Virulence-Related Heme Oxygenase Provide Insights Into Its Catalytic Mechanism, Anabel Soldano, Sebastián Klinke, Lisandro H. Otero, Mario Rivera, Daniela L. Catalano-Dupuy, Eduardo A. Ceccarelli

Faculty Publications

© 2017 Soldano et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Heme oxygenase from Leptospira interrogans is an important virulence factor. During catalysis, redox equivalents are provided to this enzyme by the plastidic-type ferredoxin-NADP+ reductase also found in L. interrogans. This process may have evolved to aid this bacterial pathogen to obtain heme-iron from their host and enable successful colonization. Herein we report the crystal structure of the heme oxygenase-heme complex at …

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Estradiol Modulates Neural Response To Conspecific And Heterospecific Song In Female House Sparrows: An In Vivo Positron Emission Tomography Study, Christine R. Lattin, Frank A. Stabile, Richard E. Carson Aug 2017

Estradiol Modulates Neural Response To Conspecific And Heterospecific Song In Female House Sparrows: An In Vivo Positron Emission Tomography Study, Christine R. Lattin, Frank A. Stabile, Richard E. Carson

Faculty Publications

© 2017 Lattin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Although there is growing evidence that estradiol modulates female perception of male sexual signals, relatively little research has focused on female auditory processing. We used in vivo 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) imaging to examine the neuronal effects of estradiol and conspecific song in female house sparrows (Passer domesticus). We assessed brain glucose metabolism, a measure of neuronal activity, in …

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Economic Growth And Mortality: Do Social Protection Policies Matter?, Usama Bilal, Richard Cooper, Francis Abreu, Claudia Nau, Manuel Franco, Thomas A. Glass Aug 2017

Economic Growth And Mortality: Do Social Protection Policies Matter?, Usama Bilal, Richard Cooper, Francis Abreu, Claudia Nau, Manuel Franco, Thomas A. Glass

Faculty Publications

Background: In the 20th century, periods of macroeconomic growth have been associated with increases in population mortality. Factors that cause or mitigate this association are not well understood. Evidence suggests that social policy may buffer the deleterious impact of economic growth. We sought to explore associations between changing unemployment (as a proxy for economic change) and trends in mortality over 30 years in the context of varying social protection expenditures. Methods: We model change in all-cause mortality in 21 OECD (Organization for Economic Cooperation and Development) countries from 1980 to 2010. Data from the Comparative Welfare States Data Set and …

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Genistein Crosses The Bioartificial Oviduct And Alters Secretion Composition, Constantine A. Simintiras, Roger G. Sturmey Aug 2017

Genistein Crosses The Bioartificial Oviduct And Alters Secretion Composition, Constantine A. Simintiras, Roger G. Sturmey

Faculty Publications

The dietary derived isoflavone and oestrogen analogue, genistein, is known to perturb fundamental reproductive events such as implantation and embryo cleavage. However the question of whether genistein is able to traverse the oviduct epithelial monolayer and impact oviduct fluid secretion remains unclear. This study tests these research questions using a bioartificial oviduct to show that genistein permeates the oviduct lumen in vitro with a biphasic (burst and plateau) kinetic profile, faster than spontaneous diffusion, and alters the amino acid composition of in vitro derived oviduct fluid (ivDOF) but not as an oestrogen analogue. In addition to offering insights into the …

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Evaluation Of Crude Larval Protein And Recombinant Somatic Protein 26/23 (Rhcp26/23) Immunization Against Haemonchus Contortus In Sheep, Omnia M. Kandil, Khaled A. Abdelrahman, Hatem A. Shalaby, Seham H.M. Hendawy, Nadia M.T. Abu El Ezz, Somia A. Nassar, James E. Miller Jul 2017

Evaluation Of Crude Larval Protein And Recombinant Somatic Protein 26/23 (Rhcp26/23) Immunization Against Haemonchus Contortus In Sheep, Omnia M. Kandil, Khaled A. Abdelrahman, Hatem A. Shalaby, Seham H.M. Hendawy, Nadia M.T. Abu El Ezz, Somia A. Nassar, James E. Miller

Faculty Publications

© Kandil, et al. Aim: The aim of this study was to evaluate the potential possibility of crude larval and recombinant (rHcp26/23) antigens of Haemonchus contortus for immunization to control sheep hemonchosis. Materials and Methods: A total of 21 lambs were divided into five groups. Lambs were immunized with larval and recombinant (rHcp26/23) proteins at day 0 and day 14 and after that challenged with 5000 infective larvae of H. contortus on day 42. An unvaccinated positive control group was challenged with L3 in the meantime. An unvaccinated negative control group was not challenged. Results: Fecal egg count reduction taking …

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Effect Of Rickettsia Felis Strain Variation On Infection, Transmission, And Fitness In The Cat Flea (Siphonaptera: Pulicidae), Sean P. Healy, Lisa D. Brown, Melena R. Hagstrom, Lane D. Foil, Kevin R. Macaluso Jul 2017

Effect Of Rickettsia Felis Strain Variation On Infection, Transmission, And Fitness In The Cat Flea (Siphonaptera: Pulicidae), Sean P. Healy, Lisa D. Brown, Melena R. Hagstrom, Lane D. Foil, Kevin R. Macaluso

Faculty Publications

© The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. Rickettsia felis is a human pathogen transmitted by the cat flea, Ctenocephalides felis (Bouché) (str. LSU), as well as an obligate symbiont of the parthenogenic booklouse Liposcelis bostrychophila (Badonnel) (str. LSU-Lb). The influence of genetic variability in these two strains of R. felis on host specialization and fitness and possible resulting differences on infection and transmission kinetics in C. felis is unknown. Utilizing an artificial host system, cat fleas were exposed to a R. felis str. LSU-Lb-infected bloodmeal and monitored for infection at 7-d …

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Louisiana Agriculture Summer, 2017, Lsu Agcenter Jul 2017

Louisiana Agriculture Summer, 2017, Lsu Agcenter

Louisiana Agriculture

No abstract provided.

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Il-4rα On Dendritic Cells In Neonates And Th2 Immunopathology In Respiratory Syncytial Virus Infection, Bishwas Shrestha, Dahui You, Jordy Saravia, David T. Siefker, Sridhar Jaligama, Greg I. Lee, Asmaa A. Sallam, Jeffrey N. Harding, Stephania A. Cormier Jul 2017

Il-4rα On Dendritic Cells In Neonates And Th2 Immunopathology In Respiratory Syncytial Virus Infection, Bishwas Shrestha, Dahui You, Jordy Saravia, David T. Siefker, Sridhar Jaligama, Greg I. Lee, Asmaa A. Sallam, Jeffrey N. Harding, Stephania A. Cormier

Faculty Publications

© Society for Leukocyte Biology. Respiratory syncytial virus (RSV) is one of the leading causes of bronchiolitis in children, and severe RSV infection early in life has been associated with asthma development. Using a neonatal mouse model, we have shown that down-regulation of IL-4 receptor α (IL-4Rα) with antisense oligonucleotides in the lung during neonatal infection protected from RSV immunopathophysiology. Significant down-regulation of IL-4Rα was observed on pulmonary CD11b+ myeloid dendritic cells (mDCs) suggesting a role for IL-4Rα on mDCs in the immunopathogenesis of neonatal RSV infection. Here, we demonstrated that neonatal CD11b+ mDCs expressed higher levels of IL-4Rα than …

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Inversion Of The Imprinting Control Region Of The Peg3 Domain, Joomyeong Kim, Hongzhi He, Hana Kim Jul 2017

Inversion Of The Imprinting Control Region Of The Peg3 Domain, Joomyeong Kim, Hongzhi He, Hana Kim

Faculty Publications

© 2017 Kim et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The imprinting of the mouse Peg3 domain is controlled through a 4-kb genomic region encompassing the bidirectional promoter and 1st exons of Peg3 and Usp29. In the current study, this ICR was inverted to test its orientation dependency for the transcriptional and imprinting control of the Peg3 domain. The inversion resulted in the exchange of promoters and 1st exons between Peg3 …

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Rare Coding Variants Associated With Blood Pressure Variation In 15 914 Individuals Of African Ancestry, Priyanka Nandakumar, Dongwon Lee, Melissa A. Richard, Fasil Tekola-Ayele, Bamidele O. Tayo, Erin Ware, Yun J. Sung, Babatunde Salako, Adesola Ogunniyi, C. Charles Gu, Megan L. Grove, Myriam Fornage, Sharon Kardia, Charles Rotimi, Richard S. Cooper, Alanna C. Morrison, Georg Ehret, Aravinda Chakravarti Jul 2017

Rare Coding Variants Associated With Blood Pressure Variation In 15 914 Individuals Of African Ancestry, Priyanka Nandakumar, Dongwon Lee, Melissa A. Richard, Fasil Tekola-Ayele, Bamidele O. Tayo, Erin Ware, Yun J. Sung, Babatunde Salako, Adesola Ogunniyi, C. Charles Gu, Megan L. Grove, Myriam Fornage, Sharon Kardia, Charles Rotimi, Richard S. Cooper, Alanna C. Morrison, Georg Ehret, Aravinda Chakravarti

Faculty Publications

Objectives: Hypertension is a major risk factor for all cardiovascular diseases, especially among African Americans. This study focuses on identifying specific blood pressure (BP) genes using 15 914 individuals of African ancestry from eight cohorts (Africa America Diabetes Mellitus, Atherosclerosis Risk in Communities Study, Coronary Artery Risk Development in young Adults, Genetics Network, Genetic Epidemiology Network of Arteriopathy, Howard University Family Study, Hypertension Genetic Epidemiology Network, and Loyola University Chicago Cohort) to further genetic findings in this population which has generally been underrepresented in BP studies. Methods: We genotyped and performed various single variant and gene-based exome-wide analyses on 15 …

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Papio Baboon Species Indicative Alu Elements, Mark Batzer, Jerilyn A. Walker, Vallmer E. Jordan, Cody J. Steely, Thomas O. Beckstrom, Cullen L. Mcdaniel, Corey P. St. Romain, Emily C. Bennett, Arianna Robichaux, Brooke N. Clement, Miriam K. Konkel Jul 2017

Papio Baboon Species Indicative Alu Elements, Mark Batzer, Jerilyn A. Walker, Vallmer E. Jordan, Cody J. Steely, Thomas O. Beckstrom, Cullen L. Mcdaniel, Corey P. St. Romain, Emily C. Bennett, Arianna Robichaux, Brooke N. Clement, Miriam K. Konkel

Faculty Publications

The genus of Papio (baboon) has six recognized species separated into Northern and Southern clades, each comprised of three species distributed across the African continent. Geographic origin and phenotypic variants such as coat color and body size have commonly been used to identify different species. The existence of multiple hybrid zones, both ancient and current, have complicated efforts to characterize the phylogeny of Papio baboons. More recently, mitochondrial DNA (mtDNA) and Y-chromosome genetic markers have been utilized for species identification with particular focus on the hybrid zones. Aluelements accumulate in a random manner and are a novel source of …

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Integrated Carbon, Sulfur, And Nitrogen Isotope Chemostratigraphy Of The Ediacaran Lantian Formation In South China: Spatial Gradient, Ocean Redox Oscillation, And Fossil Distribution, W. Wang, C. Guan, C. Zhou, Y. Peng, L. M. Pratt, X. Chen, L. Chen, Z. Chen, X. Yuan, S. Xiao Jul 2017

Integrated Carbon, Sulfur, And Nitrogen Isotope Chemostratigraphy Of The Ediacaran Lantian Formation In South China: Spatial Gradient, Ocean Redox Oscillation, And Fossil Distribution, W. Wang, C. Guan, C. Zhou, Y. Peng, L. M. Pratt, X. Chen, L. Chen, Z. Chen, X. Yuan, S. Xiao

Faculty Publications

© 2017 John Wiley & Sons Ltd The Ediacaran Doushantuo Formation in South China is a prime target for geobiological investigation because it offers opportunities to integrate chemostratigraphic and paleobiological data. Previous studies were mostly focused on successions in shallow-water shelf facies, but data from deep-water successions are needed to fully understand basinal redox structures. Here, we report δ13Ccarb, δ13Corg, δ34Spyr, δ34SCAS, and δ15Nsed data from a drill core of the fossiliferous Lantian Formation, which is a deep-water equivalent of the Doushantuo Formation. Our data confirm a large (>10‰) spatial gradient in δ13Ccarb in the lower Doushantuo/Lantian formations, but …

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Neutral Genetic Processes Influence Mhc Evolution In Threatened Gopher Tortoises (Gopherus Polyphemus), Jean P. Elbers, Rachel W. Clostio, Sabrina S. Taylor Jul 2017

Neutral Genetic Processes Influence Mhc Evolution In Threatened Gopher Tortoises (Gopherus Polyphemus), Jean P. Elbers, Rachel W. Clostio, Sabrina S. Taylor

Faculty Publications

Levels of adaptive genetic variation influence how species deal with environmental and ecological change, but these levels are frequently inferred using neutral genetic markers. Major histocompatibility complex (MHC) genes play a key role in the adaptive branch of the immune system and have been used extensively to estimate levels of adaptive genetic variation. Parts of the peptide binding region, sites where MHC molecules directly interact with pathogen and self-proteins, were sequenced from a MHC class I (95/441 tortoises) and class II (245/441 tortoises) gene in threatened and nonthreatened populations of gopher tortoises (Gopherus polyphemus), and adaptive genetic variation at MHC …

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Examining The Use Of Amazon's Mechanical Turk For Edge Extraction Of The Occlusal Surface Of Fossilized Bovid Teeth, Gregory J. Matthews, George K. Thiruvathukal, Maxwell P. Luetkemeier, Juliet K. Brophy Jul 2017

Examining The Use Of Amazon's Mechanical Turk For Edge Extraction Of The Occlusal Surface Of Fossilized Bovid Teeth, Gregory J. Matthews, George K. Thiruvathukal, Maxwell P. Luetkemeier, Juliet K. Brophy

Faculty Publications

In order to reconstruct environments associated with Plio-Pleistocene hominins in southern Africa, researchers frequently rely upon the animals associated with the hominins, in particular, animals in the Family Bovidae. Bovids in southern Africa are typically identified by their teeth. However, identifying the taxon of a bovid tooth is challenging due to various biasing factors. Furthermore, inaccurate identification of fossil bovids can have significant consequences on the reconstructed paleoenvironment. Recent research on the classification of bovid fossil teeth has relied on using elliptical Fourier analysis to summarize the shape of the outline of the occlusal surface of the tooth and the …

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Galanin-Expressing Gaba Neurons In The Lateral Hypothalamus Modulate Food Reward And Noncompulsive Locomotion, Emily Qualls-Creekmore, Sangho Yu, Marie Francois, John Hoang, Clara Huesing, Annadora Bruce-Keller, David Burk, Hans Rudolf Berthoud, Christopher D. Morrison, Heike Münzberg Jun 2017

Galanin-Expressing Gaba Neurons In The Lateral Hypothalamus Modulate Food Reward And Noncompulsive Locomotion, Emily Qualls-Creekmore, Sangho Yu, Marie Francois, John Hoang, Clara Huesing, Annadora Bruce-Keller, David Burk, Hans Rudolf Berthoud, Christopher D. Morrison, Heike Münzberg

Faculty Publications

© 2017 the authors. The lateral hypothalamus (LHA) integrates reward and appetitive behavior and is composed of many overlapping neuronal populations. Recent studies associated LHA GABAergic neurons (LHAGABA), which densely innervate the ventral tegmental area (VTA), with modulation of food reward and consumption; yet, LHAGABA projections to the VTA exclusively modulated food consumption, not reward. We identified a subpopulation of LHA GABA neurons that coexpress the neuropeptide galanin (LHAGal). TheseLHAGal neurons also modulate food reward, but lack direct VTA innervation. We hypothesized that LHAGal neurons may represent a subpopulation of LHAGABA neurons that mediates food reward independent of direct VTA …

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Akt3 Is Responsible For The Survival And Proliferation Of Embryonic Stem Cells, Ling Wang, Delun Huang, Zongliang Jiang, Yan Luo, Carol Norris, Ming Zhang, Xiuchun Tian, Young Tang Jun 2017

Akt3 Is Responsible For The Survival And Proliferation Of Embryonic Stem Cells, Ling Wang, Delun Huang, Zongliang Jiang, Yan Luo, Carol Norris, Ming Zhang, Xiuchun Tian, Young Tang

Faculty Publications

© 2017. Published by The Company of Biologists Ltd. The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt) pathway plays an important role in regulating cell proliferation, metabolism, and survival. However, the distinct roles of Akt isoforms (Akt1, Akt2, and Akt3) in pluripotent stem cell maintenance are not fully defined. Using mouse embryonic stem cells (ESCs), we show that direct inhibition of Akt activity leads to ESC apoptosis. The Akt3, but not Akt1 or Akt2, activity specifically regulates this effect. Inhibiting Akt3 also leads to a cell cycle arrest at G1 phase. These regulatory roles of Akt3 are dependent on its kinase …

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Timing Of Cherry Tree Blooming: Contrasting Effects Of Rising Winter Low Temperatures And Early Spring Temperatures, Peijian Shi, Zhenghong Chen, Gadi V.P. Reddy, Cang Hui, Jianguo Huang, Mei Xiao Jun 2017

Timing Of Cherry Tree Blooming: Contrasting Effects Of Rising Winter Low Temperatures And Early Spring Temperatures, Peijian Shi, Zhenghong Chen, Gadi V.P. Reddy, Cang Hui, Jianguo Huang, Mei Xiao

Faculty Publications

Phenology reflects the interplay of climate and biological development. Early spring phenological phenomena are particularly important because the end of diapause or dormancy is related not only to heat accumulation in the early spring but also probably to winter low temperatures. Although a warmer winter can reduce overwintering mortality in many insects and plants, it also reduces the accumulation of chilling time that often triggers the end of diapause or dormancy. We examined a continuous 67-year time series of the first flowering date of cherry trees and compared three phenological models based on the temperature-dependent developmental rate: (i) the accumulated …

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Shallow Ponds Are Heterogeneous Habitats Within A Temperate Salt Marsh Ecosystem, Amanda C. Spivak, Kelsey Gosselin, Evan Howard, Giulio Mariotti, Inke Forbrich, Rachel Stanley, Sean P. Sylva Jun 2017

Shallow Ponds Are Heterogeneous Habitats Within A Temperate Salt Marsh Ecosystem, Amanda C. Spivak, Kelsey Gosselin, Evan Howard, Giulio Mariotti, Inke Forbrich, Rachel Stanley, Sean P. Sylva

Faculty Publications

Integrating spatial heterogeneity into assessments of salt marsh biogeochemistry is becoming increasingly important because disturbances that reduce plant productivity and soil drainage may contribute to an expansion of shallow ponds. These permanently inundated and sometimes prominent landscape features can exist for decades, yet little is known about pond biogeochemistry or their role in marsh ecosystem functioning. We characterized three ponds in a temperate salt marsh (MA, USA) over alternating periods of tidal isolation and flushing, during summer and fall, by evaluating the composition of plant communities and organic matter pools and measuring surface water oxygen, temperature, and conductivity. The ponds …

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Anise Oil Dosage And Its Effect On Growth Performance And Jejunal Lesions During A Clostridium Perfringens Challenge In Battery Trials, And Growth Performance In A Floor Pen Trial, J. W. Charal, T. D. Bidner, L. L. Southern, M. E. Janes, M. E. Gutierrez, T. A. Lavergne Jun 2017

Anise Oil Dosage And Its Effect On Growth Performance And Jejunal Lesions During A Clostridium Perfringens Challenge In Battery Trials, And Growth Performance In A Floor Pen Trial, J. W. Charal, T. D. Bidner, L. L. Southern, M. E. Janes, M. E. Gutierrez, T. A. Lavergne

Faculty Publications

© 2017 Poultry Science Association Inc. Anise oil (AO) is a phytochemical with antibiotic properties and it reduces the growth of Clostridium perfringens in vitro, which is the main causal agent of necrotic enteritis. A series of battery experiments was conducted to determine an AO dosage to feed to broilers and its effect during 2 C. perfringens challenges, and a floor pen experiment to determine its effect in performance. Anise oil linearly reduced (P < 0.05) ADFI and ADG, but feeding broilers 500 to 2,000 mg/kg of AO resulted in similar performance with positive control (PC) fed broilers. Broilers were challenged on d 10 (Experiment 2) or on d 10 and 13 (Experiment 3). Broilers fed AO had lower (P < 0.05) ADFI and ADG compared with broilers fed PC from zero to 18 d (Experiment 2). Growth performance of broilers fed AO was not affected (P > 0.05) during Experiment 3. In both challenges, the jejunum of broilers fed AO had fewer and milder (P < 0.05) lesions compared with broilers fed PC or negative control (NC) diets. In a floor pen trial, 1,000 mg/kg of AO was fed to broilers from zero to 42 days. Broilers fed AO or PC had similar (P > 0.10) growth performance for the entire trial. Broilers …

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Intramuscular Immunization Of Mice With The Live-Attenuated Herpes Simplex Virus 1 Vaccine Strain Vc2 Expressing Equine Herpesvirus 1 (Ehv-1) Glycoprotein D Generates Anti-Ehv-1 Immune Responses In Mice, Shiliang A. Liu, Brent A. Stanfield, Vladimir N. Chouljenko, Shan Naidu, Ingeborg Langohr, Fabio Del Piero, Jacqueline Ferracone, Alma A. Roy, Konstantin G. Kousoulas Jun 2017

Intramuscular Immunization Of Mice With The Live-Attenuated Herpes Simplex Virus 1 Vaccine Strain Vc2 Expressing Equine Herpesvirus 1 (Ehv-1) Glycoprotein D Generates Anti-Ehv-1 Immune Responses In Mice, Shiliang A. Liu, Brent A. Stanfield, Vladimir N. Chouljenko, Shan Naidu, Ingeborg Langohr, Fabio Del Piero, Jacqueline Ferracone, Alma A. Roy, Konstantin G. Kousoulas

Faculty Publications

© 2017 American Society for Microbiology. All Rights Reserved. Vaccination remains the best option to combat equine herpesvirus 1 (EHV-1) infection, and several different strategies of vaccination have been investigated and developed over the past few decades. Herein, we report that the liveattenuated herpes simplex virus 1 (HSV-1) VC2 vaccine strain, which has been shown to be unable to enter into neurons and establish latency in mice, can be utilized as a vector for the heterologous expression of EHV-1 glycoprotein D (gD) and that the intramuscular immunization of mice results in strong antiviral humoral and cellular immune responses. The VC2-EHV-1-gD …

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Identification And Characterization Of A Solute Carrier, Cia8, Involved In Inorganic Carbon Acclimation In Chlamydomonas Reinhardtii, Marylou C. Machingura, Joanna Bajsa-Hirschel, Susan M. Laborde, Joshua B. Schwartzenburg, Bratati Mukherjee, Ananya Mukherjee, Steve V. Pollock, Britta Förster, G. Dean Price, James V. Moroney Jun 2017

Identification And Characterization Of A Solute Carrier, Cia8, Involved In Inorganic Carbon Acclimation In Chlamydomonas Reinhardtii, Marylou C. Machingura, Joanna Bajsa-Hirschel, Susan M. Laborde, Joshua B. Schwartzenburg, Bratati Mukherjee, Ananya Mukherjee, Steve V. Pollock, Britta Förster, G. Dean Price, James V. Moroney

Faculty Publications

© The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology. The supply of inorganic carbon (Ci) at the site of fixation by Rubisco is a key parameter for efficient CO2 fixation in aquatic organisms including the green alga, Chlamydomonas reinhardtii. Chlamydomonas reinhardtii cells, when grown on limiting CO2, have a CO2-concentrating mechanism (CCM) that functions to concentrate CO2 at the site of Rubisco. Proteins thought to be involved in inorganic carbon uptake have been identified and localized to the plasma membrane or chloroplast envelope. However, current CCM models suggest that additional molecular components …

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Peg3 Control On The Mammalian Msl Complex, An Ye, Hana Kim, Joomyeong Kim Jun 2017

Peg3 Control On The Mammalian Msl Complex, An Ye, Hana Kim, Joomyeong Kim

Faculty Publications

©2017 Ye et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Peg3 (paternally expressed gene 3) encodes a DNA-binding protein that functions as a transcriptional repressor. Recent studies revealed that PEG3 binds to Msl1 (male-specific lethal 1) and Msl3, the two main components of the MSL complex. In the current study, we investigated potential roles of Peg3 in controlling its downstream genes through H4K16ac, the histone modification by the MSL complex. According to …

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Investigation Of Pseudomonas Fluorescens Strain 3jw1 On Preventing And Reducing Aflatoxin Contaminations In Peanuts, Xiaona Yang, Qi Zhang, Zhi Yuan Chen, Hongxia Liu, Peiwu Li Jun 2017

Investigation Of Pseudomonas Fluorescens Strain 3jw1 On Preventing And Reducing Aflatoxin Contaminations In Peanuts, Xiaona Yang, Qi Zhang, Zhi Yuan Chen, Hongxia Liu, Peiwu Li

Faculty Publications

Pseudomonas fluorescens strain 3JW1, which has a broad-spectrum antimicrobial activity, was studied to investigate whether it affects the amounts of aflatoxin B1 (AFB1) produced by Aspergillus flavus. It was found that the bacterium reduced the amounts of AFB1 in potato dextrose broth (PDB) and peanut medium by 97.8% and 99.4%, respectively. It also reduced AFB1 by ~183 μg/kg (55.8%) when applied onto peanut kernels. This strain reduced AFB1 via three mechanisms. First, it significantly inhibited A. flavus growth; second, our data showed that strain 3JW1 inhibits aflatoxin biosynthesis by A. flavus; and third, P. fluorescens strain 3JW1 is capable of …

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Short Communication: Sensory Analysis Of A Kefir Product Designed For Active Cancer Survivors, K. O'Brien, C. Boeneke, W. Prinyawiwatkul, J. Lisano, D. Shackelford, K. Reeves, M. Christensen, R. Hayward, K. Carabante Ordonez, L. K. Stewart Jun 2017

Short Communication: Sensory Analysis Of A Kefir Product Designed For Active Cancer Survivors, K. O'Brien, C. Boeneke, W. Prinyawiwatkul, J. Lisano, D. Shackelford, K. Reeves, M. Christensen, R. Hayward, K. Carabante Ordonez, L. K. Stewart

Faculty Publications

Kefir is a fermented milk product that is a good source of protein and health-promoting bacteria. It has the potential to improve recovery from exercise and the health and well-being of cancer survivors. The purpose of this study was to explore cancer survivor attitudes about and acceptance of a kefir recovery beverage made from cultured milk, whole fruit, natural sweeteners, and other natural ingredients. Kefir was made by inoculating and fermenting milk with kefir grains. The kefir was then mixed with a fruit base and given to cancer survivors (n = 52) following a bout of exercise. Participants evaluated the …

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Papio Baboon Species Indicative Alu Elements, Jerilyn A. Walker, Vallmer E. Jordan, Cody J. Steely, Thomas O. Beckstrom, Cullen L. Mcdaniel, Corey P. St Romain, Emily C. Bennett, Arianna Robichaux, Brooke N. Clement, Miriam K. Konkel, Mark A. Batzer, Jeffrey Rogers, R. Alan Harris, Muthuswamy Raveendran, Yue Liu, Shwetha Murali, Tauras P. Vilgalys, Jerilyn A. Walker Jun 2017

Papio Baboon Species Indicative Alu Elements, Jerilyn A. Walker, Vallmer E. Jordan, Cody J. Steely, Thomas O. Beckstrom, Cullen L. Mcdaniel, Corey P. St Romain, Emily C. Bennett, Arianna Robichaux, Brooke N. Clement, Miriam K. Konkel, Mark A. Batzer, Jeffrey Rogers, R. Alan Harris, Muthuswamy Raveendran, Yue Liu, Shwetha Murali, Tauras P. Vilgalys, Jerilyn A. Walker

Faculty Publications

© The Author(s) 2017. The genus of Papio (baboon) has six recognized species separated into Northern and Southern clades, each comprised of three species distributed across the African continent. Geographic origin and phenotypic variants such as coat color and body size have commonly been used to identify different species. The existence ofmultiple hybrid zones, both ancient and current, have complicated efforts to characterize the phylogeny of Papio baboons. More recently, mitochondrial DNA (mtDNA) and Y-chromosome genetic markers have been utilized for species identification with particular focus on the hybrid zones. Alu elements accumulate in a random manner and are a …

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Behavioural Response To Song And Genetic Divergence In Two Subspecies Of White-Crowned Sparrows (Zonotrichia Leucophrys), Sara E. Lipshutz, Isaac A. Overcast, Michael J. Hickerson, Robb T. Brumfield, Elizabeth P. Derryberry Jun 2017

Behavioural Response To Song And Genetic Divergence In Two Subspecies Of White-Crowned Sparrows (Zonotrichia Leucophrys), Sara E. Lipshutz, Isaac A. Overcast, Michael J. Hickerson, Robb T. Brumfield, Elizabeth P. Derryberry

Faculty Publications

© 2016 John Wiley & Sons Ltd Divergence in sexual signals may drive reproductive isolation between lineages, but behavioural barriers can weaken in contact zones. Here, we investigate the role of song as a behavioural and genetic barrier in a contact zone between two subspecies of white-crowned sparrows (Zonotrichia leucophrys). We employed a reduced genomic data set to assess population structure and infer the history underlying divergence, gene flow and hybridization. We also measured divergence in song and tested behavioural responses to song using playback experiments within and outside the contact zone. We found that the subspecies form distinct genetic …

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Experimental Method And Statistical Analysis To Fit Tumor Growth Model Using Spect/Ct Imaging: A Preclinical Study, Ivan Hidrovo, Joyoni Dey, Megan E. Chesal, Dmytro Shumilov, Narayan Bhusal, J. Michael Mathis Jun 2017

Experimental Method And Statistical Analysis To Fit Tumor Growth Model Using Spect/Ct Imaging: A Preclinical Study, Ivan Hidrovo, Joyoni Dey, Megan E. Chesal, Dmytro Shumilov, Narayan Bhusal, J. Michael Mathis

Faculty Publications

Background: Over the last decade, several theoretical tumor-models have been developed to describe tumor growth. Oncology imaging is performed using various modalities including computed tomography (CT), magnetic resonance imaging (MRI), single-photon emission computed tomography (SPECT) and fluorodeoxyglucose-positron emission tomography (FDG-PET). Our goal is to extract useful, otherwise hidden, quantitative biophysical parameters (such as growth-rate, tumor-necrotic-factor, etc.) from these serial images of tumors by fitting mathematical models to images. These biophysical features are intrinsic to the tumor types and specific to the study-subject, and expected to add valuable information on the tumor containment or spread and help treatment plans. Thus, fitting …

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3-D Printing Provides A Novel Approach For Standardization And Reproducibility Of Freezing Devices, E. Hu, William Childress, Terrence R. Tiersch Jun 2017

3-D Printing Provides A Novel Approach For Standardization And Reproducibility Of Freezing Devices, E. Hu, William Childress, Terrence R. Tiersch

Faculty Publications

Cryopreservation has become an important and accepted tool for long-term germplasm conservation of animals and plants. To protect genetic resources, repositories have been developed with national and international cooperation. For a repository to be effective, the genetic material submitted must be of good quality and comparable to other submissions. However, due to a variety of reasons, including constraints in knowledge and available resources, cryopreservation methods for aquatic species vary widely across user groups which reduces reproducibility and weakens quality control. Herein we describe a standardizable freezing device produced using 3-dimensional (3-D) printing and introduce the concept of network sharing to …

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