Digital Commons Network^™

Firms’ Darq Readiness And Marketing Implications: A Systematic Literature Review, Ali N. Tehrani, K. Roy, Richard Gruner

Research outputs 2022 to 2026

Purpose – This study aims to systematically review literature across diverse disciplines, including marketing, management and information systems, to synthesise insights on firms’ readiness to adopt and implement DARQ technologies and their marketing implications. DARQ technologies are emerging and cutting-edge technologies, including Distributed Ledger Technology, Artificial Intelligence, Extended Reality and Quantum Computing (hence, DARQ). Design/methodology/approach – Through a systematic review of over 2, 500 papers across three databases, this study distilled a focused sample of 88 papers. It comprehensively explores the reported dimensions, antecedents, outcomes and marketing implications of firms’ readiness for DARQ technologies. Findings – This study identified three …

Social Procurement As A Catalyst For Dei In Construction: Some Takeaways For Hrm?, Jennifer Waterhouse, Robyn Keast, Judy Lundy, Martin Loosemore

Research outputs 2022 to 2026

Purpose: Diversity, equity and inclusion (DEI) initiatives aim to foster workplaces where all employees feel valued and can add value. Increasingly, the success of these initiatives is influenced by environments and interactions beyond organisational boundaries, including recent backlash. Despite this, most DEI research remains focused on intra-organisational aspects and human resource management (HRM) activities. The purpose of this paper is to introduce social procurement as a novel and promising framework for advancing DEI in theory and practice through a collaborative, inter-organisational approach that has the potential to overcome institutional barriers and mitigate backlash. Design/methodology/approach: Data were collected through 15 in-depth …

Depression, Psychological Distress, And Coping Strategies Among African Migrants In Australia: A Cross-Sectional Web-Based Study, Uchechukwu Levi Osuagwu, Lillian Mwanri, Edith N. Botchway-Commey, David Chisanga, Agness Tembo, Nnaemeka Meribe, Kathomi Gatwiri, Obed Adonteng-Kissi, Kerrie P. Doyle, Frank Darkwa Baffour, Ahmed A. Moustafa

Research outputs 2022 to 2026

Background: African migrants constitute a significant proportion of the Australian population. While migration and resettlement offer opportunities, the associated stressors may adversely affect the mental health and well-being of African migrants. This study explored, for the first time, the prevalence of depression and psychological distress among African migrants in Australia and the relationship between coping mechanisms and mental health outcomes. Methods: A web-based cross-sectional survey of adult African migrants in Australia was conducted between February and May 2022. Participants (N = 167) who did not have a refugee status who resided in Australia for at least 12 months were recruited …

Application Of The Paediatric Medical Traumatic Stress Model To The Mental Health Experience Of Young People Living With Type 1 Diabetes: A Qualitative Study, Rigel Paciente, Sara Coombs, Karen Lombardi, Helen Milroy, Keely Bebbington, Heather Roby, Craig E. Taplin, Nicole Wickens, Stella Rose, Alix Woolard

Research outputs 2022 to 2026

Despite the various traumatic events that a young person living with type 1 diabetes (T1D) may experience, little is known about the burden and manifestation of traumatic stress in this population. Though mental health outcomes have been explored generally, medical trauma-sensitive approaches to understanding these experiences remain limited. We utilised a qualitative descriptive approach to explore the impact of T1D on young people’s mental health through the paediatric medical traumatic stress model (PMTS). Young people aged 13–30 living with T1D were interviewed. These interviews were recorded, transcribed, and analysed using Reflexive Thematic Analysis. Three main themes were generated: (1) perceived …

Examining Teachers’ Attitudes Towards Inclusive Education For All: Development Of A New Scale, Stephan Kielblock, Woodcock, John Ehrich

Research outputs 2022 to 2026

Teachers’ attitudes towards inclusive education are widely recognised as a key indicator of the inclusiveness of classroom environments. However, existing instruments inadequately capture teachers’ mindsets in relation to inclusive education for all learners. This study addresses this gap by developing and validating a new cross-cultural measurement instrument: the Attitudes Towards Inclusion for All scale (ATIFA), in both English (ATIFA-EN) and German (ATIFA-DE). Data were collected from pre-service and in-service teachers in Australia (n = 146) and Germany (n = 238). Exploratory factor analysis and Rasch modelling identified four robust subscales—Philosophy, Practice, Social Inclusion, and Support—with strong psychometric properties. Evidence of …

Application Of Artificial Intelligence (Ai) In Cancer Symptom Management For Adult Cancer Survivors: A Scoping Review, Tao Wang, Haiying Wang, Mengyuan Li, Daniel Bressington, Daniel Terry, Guanjin Wang, Wai Hang Kwok, Jing Yu (Benjamin) Tan

Research outputs 2022 to 2026

Background and aim: Artificial Intelligence (AI) has been increasingly used in cancer survivorship to support symptom management. This scoping review aimed to map existing evidence on AI applications in cancer symptom management for adult cancer survivors, including AI model development, AI-enabled intervention delivery and adoption, symptom targets, key features of the AI approaches used, reported outcomes, influencing factors, and research gaps to inform future priorities.

Method: This scoping review was conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews. Eight electronic databases were comprehensively searched in November 2025 and updated in March 2026. Empirical studies published in …

The Unacknowledged Challenge Of Moral Distress For Nurse Academics, Adam Burston, Glenna Mae Guiriba, Meena Gupta, Sara Bayes

Research outputs 2022 to 2026

The pluralistic nature of healthcare presents nurses with situations challenging their moral values which nurses must navigate. Challenges to moral values can result in the experience of moral distress, a problem that is common within the clinical nursing context. Moral distress is a known and well-researched phenomenon within nursing and has long contributed to detrimental effects such as frustration, anger, anxiety, decreased job satisfaction, burnout and ultimately attrition. However, despite extensive research in clinical environments, minimal research exists detailing this concept within the context of nursing academics and educators. Nurses can experience moral distress if they are in or exposed …

Values, Flourishing, And Identity Integration: Understanding Alcohol And Other Drug Use Among African Australian Youth, Abraham Kenin, Justine Dandy, Kwadwo Adusei-Asante, Sonam Pelden

Research outputs 2022 to 2026

Previous research suggests Alcohol and Other Drug (AOD) use by sub-Saharan African (SSA) youth who emigrate to Western cultural contexts like Australia is an indication of their acculturation and is influenced by their values. Although values are distal predictors of AOD use, the extent to which SSA Australian youth apply their values in AOD use could be a function of their psychological flourishing and Bicultural Identity Integration (BII). The aim of this study was to test a predictive model that combines values, psychological flourishing and BII to explore how the interaction of personal values and adaptive resources are related to …

Curiosity In Tourism: A Review And Future Directions, Sten Langmann, Pieter Jan Bezemer, Eerang Park, Sangkyun Kim

Research outputs 2022 to 2026

Curiosity increasingly attracts attention in tourism research. However, the field remains conceptually fragmented around what curiosity is and how it works, often pointing to related yet different understandings of the concept. Drawing on an in-depth analysis of 61 peer-reviewed articles, we aim to build a more coherent agenda for future research by answering two core questions: how has curiosity been conceptualised and studied in tourism research, and what gaps and directions emerge from the literature? The analysis reveals that curiosity has been studied in four primary ways in tourism research: an innate motivational driver, a situational mediating state, an outcome …

Underfunded And Undervalued: Community-Based Health Promotion Practitioners’ Experiences Of Western Australia’S Prevention Sector, Ruth M. Wallace, Leesa N. Costello, Elizabeth J. Cook

Research outputs 2022 to 2026

Prevention is a central policy focus of contemporary health promotion, offering cost-effective strategies to reduce disease burden and improve population well-being. Despite this, Australia allocates a small proportion of its health budget to prevention, with funding models characterized by short-term cycles and competitive tendering. While the consequences for public health are well documented, the impact on the health promotion workforce remains underexplored. Workforce health and stability are critical for program delivery, ethical practice, continuity of relationships with communities, and the capacity to sustain long-term prevention efforts. This qualitative study examined the experience of 19 community-based health promotion practitioners in Western …

Culturally Safe Nursing: Transformative Learning Experiences Through Critical Reflection Assessment, Lesley Andrew, Michelle Pedlow, Bev Ewens

Research outputs 2022 to 2026

Aim: To explore the transformative learning experiences of postgraduate nursing students engaging in an Aboriginal culture and history module, through an analysis of a critical reflection assessment, in particular the student development of cultural awareness and culturally safe practice.

Background: Despite mandated inclusion of Aboriginal cultural content in Australian nursing curricula, culturally unsafe practices and racism persist. Transformative learning, underpinned by critical reflection, can challenge fixed assumptions and promote cultural awareness and culturally safe care.

Design: A qualitative descriptive study using thematic analysis. Methods: Written critical reflections from 15 consenting postgraduate nursing students who completed the Ngany Kalyakal Katatjiny Boordawan …

Rank, Degrading Treatment, And The Italy-Albania Agreement, Jamal Barnes, Obed Adonteng-Kissi

Research outputs 2022 to 2026

In November 2023, Italy signed a five-year agreement with Albania to transfer asylum seekers intercepted in international waters by Italian vessels to Italian-run detention centres in Albania for asylum processing and deportation. The agreement has been controversial and raises several human rights issues. This article examines these human rights concerns and argues that the agreement is degrading by design. Analysing policy documents, legal cases, speeches, international human rights and refugee law, and philosophical and legal scholarship on the concept of degrading treatment, this article argues that the cumulative effect of subjecting people to unnecessary suffering, discrimination, and dehumanisation creates a …

Disrupted Trajectories: Covid-19, Transnational Youth Mobility And Unequal Transitions To Adulthood, Simon Chambers, Anita Harris, Loretta Baldassar

Research outputs 2022 to 2026

While the impact of COVID-19 on youth development has been widely studied, less is known about its effects on transnationally mobile young adults. This longitudinal study of Australian outbound and inbound mobility examines how the pandemic disrupted this population's experiences abroad as they navigated transitions to adulthood. It draws on two waves of survey data collected using a convenience sample between July 2020 and September 2022. Our findings reveal that COVID-19 presented significant challenges to young adults living away from home, with disruptions to their future plans, social connections, and well-being. However, these impacts were not uniform. The pandemic magnified …

Is The Crisis Over? Fostering Innovative Work Behavior In Response To The Constant Pressure Of Resource-Deficiency For Street Level Bureaucrats: The Impact Of Psychosocial Safety Climate, Teamwork, And Work Engagement, Yvonne Brunetto, Matthew Xerri, Geremy Farr-Wharton

Research outputs 2022 to 2026

There is conflicting evidence about the pathways Street Level Bureaucrats’ (SLBs’) use to engage Innovative Work Behavior (IWB). This study uses Street Level Bureaucrat (SLB) and Conservation of Resources (COR) to examine the extent to which SLBs’ work engagement and/or burnout mediates the relationship between Psychosocial Safety Climate (PSC) and teamwork, and IWB. The methods comprised a sample of 259 healthcare SLBs (doctors, nurses, allied health) collected at two times, and analyzed using structural equation modeling. The results show that the variance of PSC and teamwork explained a third of engagement, and engagement-burnout mediated the impact of PSC and teamwork …

Prospective Effects Of Positive Resilience Resources During Young Adulthood: Predicting Daily Stress Responses Three Years Later Amidst A Changing World, Melissa Elwin, Bep Uink, Rachel Delahaye, Alana Battel, Jasmine Powell, Stefano Occhipinti, Jacqueline Allen, Kathryn L. Modecki

Research outputs 2022 to 2026

Background: With young adults' rates of mental health problems alarmingly high, understanding resilience characteristics that help young people adapt, adjust, and even thrive in the face of stress is a pressing need. This study takes a daily diary approach, examining four resilience factors, measured a priori, covering multiple domains. Young adults' daily stress responses (reactivity, recovery, inertia) during the globally stressful lockdown period three years later were then explored as key outcomes. Methods: Leveraging two waves of data, young adults (ages 17–25, N = 108) completed demographic and psychometric measures at Wave 1. Resilience factors were operationalized using residualized scores …

The Future Midwife: A Prisma Scoping Review Of Education, Transition, And Work Readiness Among Midwifery Students, Danielle Gleeson, Tracey Tulleners, Jessica Elliott, Dianne Stratton-Maher, Liz Ryan, Jillian Mcculloch, Geraldine Roderick, Thenuja Jayasinghe, Joanne Buckley, Jamie May Newman, Helen Nutter, Jo Southern, Lisa Beccaria, Georgina Sheridan, Tess Trinder, Haiying Wang, Tao Wang, Sita Sharma, Linda Ng, Jing Yu Tan, Daniel Terry

Research outputs 2022 to 2026

Background: Preparing midwifery graduates to be confident, competent, and resilient is essential for workforce sustainability, yet students report a disconnect between academic preparation and clinical realities. Increasing care complexity, workforce shortages, and variable clinical learning environments globally highlight the need to examine how educational strategies support effective transition to practice. Objective: To map and synthesise the evidence regarding educational approaches, learning experiences, and transition-to-practice factors that influence preparedness for professional practice among midwifery students, and to identify gaps in the existing literature to inform a coherent and future-ready educational framework.

Methods: A PRISMA-ScR-guided scoping review was conducted across seven databases. …

What Is Left After Memory: Love, The Body, And The Unconscious In Little Fish, Paul Longley Arthur, Isabel Smith

Research outputs 2022 to 2026

Chad Hartigan’s science fiction romantic drama Little Fish was released in 2020, soon after the start of the COVID-19 pandemic. However, the disease plaguing communities in Little Fish is not affecting people’s bodies but their minds—those who have contracted Neuroinflammatory Affliction (NIA) are losing their memories. The story centres upon the experiences of one young couple as they anxiously witness the disease take hold of their community, loved ones, and eventually one another. The film explores relationships between memory and identity, and poses questions about the ways these processes interact with those of love and loss. Who are we once …

Musical Training Increases Anticipatory Responding And Predictive Control In Sequence Learning, Li Ann Leow, Jarrad Lum, Sara Johnson, Emily Corti, Welber Marinovic

Research outputs 2022 to 2026

Musicians demonstrate advantages in acquiring motor sequences, showing faster learning and better explicit sequence knowledge than non-musicians. However, it is unclear whether this advantage extends beyond acquisition to the consolidation phase, which is when newly learned skills stabilize and become resistant to interference. Additionally, while interference from executing competing motor tasks is well-established, less is known about whether purely sensory information presented after learning can disrupt consolidation of a bimodal motor sequence. We investigated how post-acquisition sensory interference affects performance of a learned audio-visual sequence, and whether musical training moderates this vulnerability. Participants first learned an explicit sequence in a …

Yorga Moorditj Koort: Aboriginal And Torres Strait Islander Women’S Perspectives About Heart Health On Noongar Boodjar, Elia Bidgood, Cathy Garlett, Richard Chenhall, Amie Bingham, Francine Eades, Emily Banks, Melinda J. Carrington, Grace Joshy, Sandra Eades, Tabassum Rahman

Research outputs 2022 to 2026

In Australia, despite overall declines in cardiovascular disease (CVD)-related mortality, Aboriginal and Torres Strait Islander women develop heart disease earlier and experience more than twice the rate of related morbidity and mortality compared with non-Indigenous women. This study explores Aboriginal women’s understandings of the factors that shape their heart health and lived experiences of CVD. We spoke with 28 Aboriginal women aged ≥18 years—15 semistructured interviews and two yarning circles with an additional 13 Aboriginal women—with/without pre-existing CVD, and 10 healthcare professionals (HCPs) working with Aboriginal communities in the Perth metropolitan region, between May 2024 and April 2025. Data were …

Dietary Patterns And Cognitive Decline In Older Adults: Findings From The Western Australia Memory Study, Carolina Blagojevic Castro, Samantha L. Gardener, Farzana Jahan, Juliana Chen, Belinda M. Brown, Ruey L. Loo, Kevin Taddei, Stephanie R. Rainey-Smith, Michael Weinborn, Ana Caroline R.Dos Reis, Manohar L. Garg, Ralph N. Martins, Hamid R. Sohrabi

Research outputs 2022 to 2026

Background: Preventive strategies, including adherence to specific dietary patterns, have received increasing attention as approaches to reduce cognitive decline and dementia risk. However, findings remain inconsistent, partly due to differences in dietary assessment methods, cognitive outcomes, and THE consideration of genetic susceptibility factors such as apolipoprotein E (APOE) genotype.

Methods: This study examined associations between dietary patterns and longitudinal cognitive change in 185 older adults without dementia from the Western Australia Memory Study. Participants completed a food frequency questionnaire at baseline and underwent comprehensive neuropsychological assessments at baseline and up to five follow-up visits at 18-month intervals. Composite scores were …

Safety And Effectiveness Of Behavioural Activation For Chronic Pain: A Protocol For A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Fangyuan Zheng, Laura Hynes, Richard J. Gray, Irene Ngune, Jacqueline Sin, Martin Jones

Research outputs 2022 to 2026

Background/Objectives: Chronic pain is a prevalent and complex condition associated with substantial physical, psychological, and social burden. Behavioural activation (BA), a structured psychological intervention originally developed for depression, may be relevant to chronic pain through its focus on reducing behavioural avoidance and increasing engagement in meaningful activities. Although BA has been applied in studies involving people with chronic pain, the safety and effectiveness of BA in this population have not been comprehensively synthesised. This systematic review and meta-analysis will examine the safety and effectiveness of BA for people with chronic pain.

The Reliability And Validity Of Manual Palpation To Assess Lower Limb Arterial Occlusion Pressure In Older Adults, For Application In Blood Flow Restriction Exercise, Michael Beere, Isaac Selva Raj, Jeremiah J. Peiffer, Keith D. Hill, Peter K. Edwards, Belinda Brown, Brendan R. Scott

Research outputs 2022 to 2026

(A) Investigate test-retest reliability of posterior tibial pulse palpation to determine arterial occlusion pressure (AOP) and examine validity against hand-held Doppler ultrasound. (B) Investigate the suitability of using 130% systolic brachial blood pressure for prescribing cuff inflation pressure for blood flow restriction (BFR) exercise. Repeated measures, crossover design. Lower limb AOP was assessed in 20 adults ≥ 60 years using hand-held Doppler ultrasound and posterior tibial pulse palpation. Brachial systolic blood pressure (bSBP) was measured to predict cuff inflation pressures (bSBP130%). On three occasions > 24 hours apart, three AOP measurements were recorded by the same blinded rater to determine intra-rater …

Unilateral Numbers Need Context: Reference Values For Single-Leg Cmj Performance Relative To Bilateral Cmj Capacity, Karol Kruczek, Tim Gabbett, Jason Lake, Michał Nowak

Research outputs 2022 to 2026

The single-leg countermovement jump (SL CMJ) is widely used to assess limb-specific neuromuscular function, with interpretation commonly centred on inter-limb asymmetry. However, contextualising unilateral performance relative to bilateral capacity remains less clearly defined. This retrospective cross-sectional study aimed to develop exploratory descriptive benchmarks for SL CMJ kinetic, kinematic, and temporal variables expressed as a percentage of bilateral CMJ performance in a heterogeneous athletic cohort. A total of 348 athletes completed bilateral and unilateral CMJs using dual force plate sampling at 1000 Hz. The best trials were selected using the modified reactive strength index (mRSI), and averaged unilateral variables were expressed …

Codesign And Implementation Of A Tai Chi Intervention For Managing The Fatigue, Sleep Disturbance And Depression Symptom Cluster In Breast Cancer Survivors In Regional Australia: A Feasibility Study Protocol, Suellen Skinner, Wai Hang Kwok, Jing Yu Benjamin Tan, Tao Wang, Daniel Bressington, Liqun Yao, Brona Nic Giolla Easpaig

Research outputs 2022 to 2026

Introduction: Breast cancer survivors (BCS) often experience side effects such as the fatigue, sleep disturbance and depression symptom cluster (FSDSC). Previous studies have demonstrated the potential efficacy of Tai Chi (TC) for improving FSDSC in BCS in a hospital setting in China. This study will explore the feasibility, acceptability and preliminary effects of the Easy 8 Form TC protocol as an adjuvant therapy in BC survivorship care, adapted to a regional Australian community setting.

Methods and analysis: The purpose of the present study is to provide a codesigned TC protocol. This multimethod study comprises a codesign study, followed by a …

Limited Australian Clinical Guidelines For Pain Assessment In Hospitalized Older Adults With Cognitive Impairment: Implications For Safe And Quality Care, Rosemary Saunders, Kaoru Nosaka, Seng Giap Marcus Ang, Natasya Raja Azlan, Aaron Alejandro, Rohini Sharma Bhardwaj, Olivia Gallagher, Irene Ngune, Amineh Rashidi, Yan Hui Celestine Wee, Nilufeur Mckay

Research outputs 2022 to 2026

Introduction – Pain assessment remains challenging in healthcare settings in patients who are unable to self-report their pain. More than 50% of individuals with dementia and other forms of cognitive impairment (CI) experience pain daily. However, pain is frequently overlooked and inadequately assessed by healthcare professionals due to their lack of knowledge and guidelines to inform pain assessment. Pain is also a leading cause of hospital presentation and inappropriate pain assessment can impact on pain management and compromise safe and quality care. Evidence-based guidelines that inform appropriate pain assessment and management are therefore essential. This scoping review aimed to explore …

Applying The Ottawa Charter To Evaluate Health Literacy Outcomes Of The Little Aussie Bugs Course For Australian Early Childhood Educators, Amelia Ruscoe, Elizabeth J. Cook, Eleanor K. O'Brien, Leesa N. Costello, Gillian Kirk, Ros Sambell, Theresa Rayfield, Amanda Devine, Ruth M. Wallace

Research outputs 2022 to 2026

Early childhood offers an important opportunity to lay the foundations for lifelong health literacy. The Little Aussie Bugs (LAB) dialogic book series and online professional development (PD) course were designed to support Early Childhood Education and Care (ECEC) educators to embed health literacy concepts, including hygiene, healthy eating, and oral health, into everyday learning routines. This mixed methods study evaluated the course pilot and examined its contribution through the lens of the Ottawa Charter for Health Promotion—a framework comprising five interrelated action areas: building healthy public policy; creating supportive environments; strengthening community action; developing personal skills; and reorienting health services. …

Sales Innovativeness Climate And B2b Salesperson Performance: The Roles Of Persistence, Entrepreneurial Self-Efficacy And Creative Selling, John Charles Peter Edwards, Steven Peter D'Alessandro, Morgan Miles

Research outputs 2022 to 2026

Purpose: Persistence is widely viewed as essential for success in business to business (B2B) selling, yet it remains unclear how persistence translates into higher sales performance when selling requires experimentation and novel customer solutions. This study examines whether a perceived sales innovativeness climate enables persistence and entrepreneurial self-efficacy (ESE) and, in turn, creative selling, driving B2B sales performance.

Design/methodology/approach: An online survey of 346 US-based B2B salespeople was analyzed using partial least squares structural equation modelling (PLS-SEM).

Findings: The perceived sales-innovativeness climate is positively associated with ESE, persistence, and sales performance. Persistence is positively related to sales performance and ESE, …

Transformative Phygital Service Research (Tpsr): An Agenda For Future Research, Saadia Shabnam, Sanjit K. Roy, Yonathan Silvain Roten, Gaganpreet Singh, Taewon Suh, Hairong Li

Research outputs 2022 to 2026

Purpose – This paper aims to develop a transformative phygital service research (TPSR) framework to explain how hybrid physical-digital service systems shape consumer well-being, autonomy, dignity and inclusion. While prior phygital service research (PSR) advances understanding of hybrid experiences and human-centred ecosystems, key ambiguities persist around agency, governance and interpretive labour in algorithmically mediated interactions. Existing frameworks address value co-creation but lack clarity on how digitally enforced rules and redistributed labour drive transformation. TPSR addresses this gap by theorising contradiction-driven processes through which human–AI arrangements and socio-technical dynamics produce both empowering and erosive outcomes in phygital service environments. Design/methodology/approach – …

Undercooked Or Over Easy? Perceptions Of Initial Teacher Educators On The Growth Of Alternative Authority To Teach Contracts, Sharon A. Louth, Linda Mahony

Australian Journal of Teacher Education

The practice of employing pre-service teachers (PST) in schools prior to the completion of their teacher training, has grown over the last three years as the teacher shortage across Australia and the world worsens. This study examines the perceived impact of Alternative Authority to Teach (AAT) contracts on the teaching profession through the lens of university lecturers working within the Initial Teacher Education (ITE) space. This phenomenological research sought to gain a wider understanding of the impact of AAT contracts on ITE stakeholders and their PST. Qualitative semi-structured interviews were conducted with eleven university lecturers. A thematic analysis of the …

Cognitive Decline In Dutch-Type Hereditary And Sporadic Cerebral Amyloid Angiopathy: A 5-Year Follow-Up Study, Rosemarie Van Dort, Vera C.J. Van Stek-Smits, Sanne E. Schriemer, Reinier G.J. Van Der Zwet, Manon R. Schipper, Sabine Voigt, Ellen P. Hart, Vandhana Easwaran, Hamid R. Sohrabi, Kevin Taddei, Samantha L. Gardener, Ralph N. Martins, Steven M. Greenberg, Matthias J.P. Van Osch, Marianne A.A. Van Walderveen, Marieke J.H. Wermer, Ellis S. Van Etten

Research outputs 2022 to 2026

Introduction: Cerebral amyloid angiopathy (CAA) is associated with cognitive impairment, but its longitudinal course of cognitive decline remains unclear. We investigated domain-specific cognitive trajectories in Dutch-type hereditary (D-CAA) and sporadic CAA (sCAA) to compare patterns and rates of decline. Methods: We included 181 participants – 93 D-CAA mutation carriers (59 without, 34 with prior intracerebral hemorrhage [ICH]) and 88 with sCAA (57 without, 31 with ICH) – who underwent annual neuropsychological assessment. Longitudinal change in global cognition, memory, processing speed, and executive function was analyzed using linear mixed models. Results: Over 5 years, cognitive decline was subtle but measurable. Memory …