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An Open-Source Evaluation Framework For Risc-V Co-Design-Based Decimal Arithmetic, Riaz Ul Haque Mian, Michiko Inoue Aug 2026

An Open-Source Evaluation Framework For Risc-V Co-Design-Based Decimal Arithmetic, Riaz Ul Haque Mian, Michiko Inoue

Research outputs 2022 to 2026

Hardware–software co-design is a balanced strategy for computationally intensive algorithms such as decimal computing. It can provide several Pareto points for the development of embedded systems in terms of hardware cost and performance. In this study, we propose an efficient and accurate evaluation framework for decimal computing. The framework was designed and developed for hardware–software co-design decimal arithmetic using the RISC-V ecosystem. New binary and decimal-oriented instructions supported by an accelerator were developed. The framework can perform cycle-accurate analysis for performance and assess hardware overhead for co-design-based decimal arithmetic. Unlike previous studies that focused primarily on implementing and evaluating individual …


Attenuation Of Redox Interference In Ruo2 Ph Sensor Using A Ta2o5/Nafion Multilayer Architecture, Wade Lonsdale, Magdalena Wajrak, Md Mahamudul Hassan, James Jin Kang Aug 2026

Attenuation Of Redox Interference In Ruo2 Ph Sensor Using A Ta2o5/Nafion Multilayer Architecture, Wade Lonsdale, Magdalena Wajrak, Md Mahamudul Hassan, James Jin Kang

Research outputs 2022 to 2026

Despite the growing preference for solid-state pH sensors due to their advantages over glass pH electrodes, their practical application is still limited by challenges, particularly in metal-oxide based systems. The main issue is their susceptibility to redox-active species such as dissolved oxygen, ascorbic acid, sulfides, and transition-metal ions. In this work, the effects of representative redox interferents, with particular emphasis on ascorbic acid, together with dissolved oxygen and potassium permanganate, were investigated and mitigated through the application of Ta2O5/Nafion overlayers. The solid-state metal-oxide pH-sensitive electrodes were fabricated with laser micro-etching of radio-frequency (RF) sputtered RuO2 thin films deposited on ceramic …


Constitutive Behaviour, Failure Mechanisms, And Life Cycle Assessment Of Internally Cured Fiber-Reinforced High-Strength Concrete, Kastro Kiran V, Dhanya Sathyan, Sanjay Kumar Shukla Aug 2026

Constitutive Behaviour, Failure Mechanisms, And Life Cycle Assessment Of Internally Cured Fiber-Reinforced High-Strength Concrete, Kastro Kiran V, Dhanya Sathyan, Sanjay Kumar Shukla

Research outputs 2022 to 2026

High-strength concrete (HSC) with low water-to-cement ratios undergoes self-desiccation, resulting in incomplete hydration, capillary porosity, and autogenous shrinkage that can compromise long-term performance. Polyethylene glycol (PEG) functions as an internal curing agent by releasing stored water as internal relative humidity decreases, thereby sustaining hydration within the cement matrix. However, the combined influence of PEG grade, dosage, and fibre type on the constitutive response, fracture behaviour, and environmental performance of M65 HSC remains insufficiently understood. This study investigated twelve concrete mixes incorporating three curing regimes viz. Conventional curing, spray curing, and PEG-based internal curing (IC) using PEG 4000 (1.5%) and PEG …


Dietary Vitamin K Intakes And Atherosclerotic Cardiovascular Disease Incidence: Findings From The Uk Biobank, Montana Dupuy, Chengfeng Li, Pratik Pokharel, Liezhou Zhong, Benjamin H. Parmenter, Simone Radavelli-Bagatini, Jack Dalla Via, Allan Linneberg, Jette Jakobsen, Tilman Kühn, Aedín Cassidy, Jonathan M. Hodgson, Joshua R. Lewis, Marc Sim, Nicola P. Bondonno Aug 2026

Dietary Vitamin K Intakes And Atherosclerotic Cardiovascular Disease Incidence: Findings From The Uk Biobank, Montana Dupuy, Chengfeng Li, Pratik Pokharel, Liezhou Zhong, Benjamin H. Parmenter, Simone Radavelli-Bagatini, Jack Dalla Via, Allan Linneberg, Jette Jakobsen, Tilman Kühn, Aedín Cassidy, Jonathan M. Hodgson, Joshua R. Lewis, Marc Sim, Nicola P. Bondonno

Research outputs 2022 to 2026

Background and aims: Vitamin K is essential for processes that inhibit vascular and valvular calcification, attributes of atherosclerotic cardiovascular diseases (ASCVDs) and aortic stenosis (AS). Relationships between dietary vitamin K1 and K2 intakes, ASCVD and AS were explored.

Methods: In 112,111 participants from the UK Biobank without ASCVD or AS (median age 59.7 years, 57.3% female), dietary vitamin K1 (μg/day) and K2 (μgPKeq/day) intakes were calculated from Oxford WebQ 24-h dietary questionnaires, using vitamin K food composition databases. Associations with incident ASCVD, ASCVD subtypes and AS, obtained from self-reports, primary care data, hospital records and death registries, were examined using …


Gut Microbiome Changes In Preclinical Alzheimer’S Disease, D. M. Sithara Dissanayaka, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Thilini N. Jayasinghe, Vincent Ho, Vijay Jayasena, Kevin Taddei, Colin L. Masters, Ralph N. Martins, W. M.A.D.Binosha Fernando Aug 2026

Gut Microbiome Changes In Preclinical Alzheimer’S Disease, D. M. Sithara Dissanayaka, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Thilini N. Jayasinghe, Vincent Ho, Vijay Jayasena, Kevin Taddei, Colin L. Masters, Ralph N. Martins, W. M.A.D.Binosha Fernando

Research outputs 2022 to 2026

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that develops many years before clinical symptoms appear. The biological changes involved in the earliest stages remain poorly understood, particularly during the preclinical stage. Our previous work has identified gradual gut microbial and metabolic changes during this stage, suggesting these may represent early biological shifts that precede disease progression. Recent studies suggest that the gut microbiome may contribute to early AD processes through its effects on immune regulation, metabolism, and gut–brain communication. Changes in gut microbial composition, including reduced levels of short-chain fatty acid (SCFA)-producing bacteria, such as Faecalibacterium, Roseburia, and Eubacterium, …


Is There Mush-Room For Bettongs On Dirk Hartog Island? Environmental Dna Assessment Of Food Resource Availability For Fauna Translocations, Rebecca J. Quah, Saul J. Cowen, Kelly J. Rayner, Aaron J. Brace, Robert A. Davis, Harriet R. Mills, Anna J.M. Hopkins Aug 2026

Is There Mush-Room For Bettongs On Dirk Hartog Island? Environmental Dna Assessment Of Food Resource Availability For Fauna Translocations, Rebecca J. Quah, Saul J. Cowen, Kelly J. Rayner, Aaron J. Brace, Robert A. Davis, Harriet R. Mills, Anna J.M. Hopkins

Research outputs 2022 to 2026

Conservation translocations require careful assessment of dietary resources to ensure population viability. Here, we used environmental DNA metabarcoding to characterise fungal assemblages across three major habitat types on Dirk Hartog Island, Western Australia, prior to the planned reintroduction of two threatened mycophagous species: the boodie (Bettongia lesueur) and woylie (Bettongia ogilbyi). We detected 243 fungal ASVs, of which 75 represented taxa that are likely to produce macroscopic fruiting bodies accessible to mycophagous mammals. Ectomycorrhizal fungi dominated all habitats, with Pezizaceae being the most abundant family—a pattern consistent with known dietary preferences of both species across multiple Australian locations. Fungal community …


Reinforcement Learning For Cathode Material Design Through Sequential Decision-Making Frameworks, Taimoor Muzaffar Gondal, Muhammad Qasim, Yasir Arafat Aug 2026

Reinforcement Learning For Cathode Material Design Through Sequential Decision-Making Frameworks, Taimoor Muzaffar Gondal, Muhammad Qasim, Yasir Arafat

Research outputs 2022 to 2026

The cathode material design is a persistent challenge in the development of next-generation rechargeable batteries. The cathode performance is critically influenced by certain key parameters, i.e., composition, crystal structures, ion transport, and degradation behaviour. Moreover, techno-economic and sustainable considerations also play a pivotal role in the viable cathode material design. In recent years, the integration of static machine learning models with conventional experimental techniques has significantly enhanced the cathode material design. However, the sequential nature of cathode discovery has not been fully captured by these techniques as they do not update their decision strategy based on prior outcomes. In this …


Unilateral Numbers Need Context: Reference Values For Single-Leg Cmj Performance Relative To Bilateral Cmj Capacity, Karol Kruczek, Tim Gabbett, Jason Lake, Michał Nowak Aug 2026

Unilateral Numbers Need Context: Reference Values For Single-Leg Cmj Performance Relative To Bilateral Cmj Capacity, Karol Kruczek, Tim Gabbett, Jason Lake, Michał Nowak

Research outputs 2022 to 2026

The single-leg countermovement jump (SL CMJ) is widely used to assess limb-specific neuromuscular function, with interpretation commonly centred on inter-limb asymmetry. However, contextualising unilateral performance relative to bilateral capacity remains less clearly defined. This retrospective cross-sectional study aimed to develop exploratory descriptive benchmarks for SL CMJ kinetic, kinematic, and temporal variables expressed as a percentage of bilateral CMJ performance in a heterogeneous athletic cohort. A total of 348 athletes completed bilateral and unilateral CMJs using dual force plate sampling at 1000 Hz. The best trials were selected using the modified reactive strength index (mRSI), and averaged unilateral variables were expressed …


What Is Left After Memory: Love, The Body, And The Unconscious In Little Fish, Paul Longley Arthur, Isabel Smith Aug 2026

What Is Left After Memory: Love, The Body, And The Unconscious In Little Fish, Paul Longley Arthur, Isabel Smith

Research outputs 2022 to 2026

Chad Hartigan’s science fiction romantic drama Little Fish was released in 2020, soon after the start of the COVID-19 pandemic. However, the disease plaguing communities in Little Fish is not affecting people’s bodies but their minds—those who have contracted Neuroinflammatory Affliction (NIA) are losing their memories. The story centres upon the experiences of one young couple as they anxiously witness the disease take hold of their community, loved ones, and eventually one another. The film explores relationships between memory and identity, and poses questions about the ways these processes interact with those of love and loss. Who are we once …


Self-Managed Non-Pharmacological Interventions For Post-Treatment Upper Limb Dysfunction Rehabilition Among Breast Cancer Survivors: A Systematic Review, Jinqiu Li, Jing Yu (Benjamin) Tan, Tao Wang, Haiying Wang, Mengyuan Li, Sita Sharma, Linda Deravin, Daniel Terry Aug 2026

Self-Managed Non-Pharmacological Interventions For Post-Treatment Upper Limb Dysfunction Rehabilition Among Breast Cancer Survivors: A Systematic Review, Jinqiu Li, Jing Yu (Benjamin) Tan, Tao Wang, Haiying Wang, Mengyuan Li, Sita Sharma, Linda Deravin, Daniel Terry

Research outputs 2022 to 2026

Purpose: This study aims to identify commonly utilised self-managed non-pharmacological interventions for managing post-treatment ULD among breast cancer survivors, evaluate their effectiveness and safety, and identify the research gaps for future studies. Methods: A systematic review was conducted, and eight English databases (PubMed, Cochrane Library, Embase, CINAHL, Web of Science, Scopus, PsycINFO, and ProQuest) were searched from their inception to 30 September 2025. Google and ResearchGate were also searched to identify any additional eligible studies. Narrative synthesis was used for data analysis. Risk of Bias version 2 was used to assess the quality of the included studies. Results: 5972 studies …


Policy And Regulation In Virtual Power Plants Development, Hemlal Bhattarai, Aziz, Stefan Lachowicz Aug 2026

Policy And Regulation In Virtual Power Plants Development, Hemlal Bhattarai, Aziz, Stefan Lachowicz

Research outputs 2022 to 2026

Electricity systems are changing due to the rapid deployment of distributed energy resources (DER), which also presents significant regulatory obstacles to their coordinated integration into energy markets and power grids. However, the majority of current material in publications concentrate on operational optimization and technical architectures, with little systematic synthesis of the legal and policy frameworks governing the deployment of VPP on a broad scale. To provide grid services, improve flexibility and support decarbonization objectives, virtual power plants (VPP) have become a crucial aggregation method. To close this gap, this research critically looks at the institutional roles, market structures, global policy …


Climate-Driven Degradation And Lifecycle Reliability Of Building-Integrated Photovoltaic Systems: Integration Challenges And Deployment Pathways, Mohammad Nur-E-Alam, Mohammad Khairul Basher, Mohammad Tariqul Islam, Mongi Amami, Rajesh Haldhar, M. Khalid Hossain Aug 2026

Climate-Driven Degradation And Lifecycle Reliability Of Building-Integrated Photovoltaic Systems: Integration Challenges And Deployment Pathways, Mohammad Nur-E-Alam, Mohammad Khairul Basher, Mohammad Tariqul Islam, Mongi Amami, Rajesh Haldhar, M. Khalid Hossain

Research outputs 2022 to 2026

Building-integrated photovoltaics (BIPV) are becoming a more popular source of renewable energy. It is an on-site renewable energy source within buildings but has limited growth due mainly to lifespan issues throughout the entire life cycle from manufacturing to design, installation, electrical integration, operation, and end of life. This paper reviews the climate-driven deterioration mechanisms of BIPV, including thermal cycling, moisture ingress, atmospheric pollutants, wind loads, etc. They relate these climate-driven deterioration mechanisms to BIPV performance deterioration, energy yield reductions, safety concerns related to energy loss, and long-term reliability of BIPV systems across all parts of the BIPV life cycle. Through …


Attraction Of Nocturnal Scarab Beetles By Unusual Floral Volatiles In A Banksia (Proteaceae) With Functionally Diverse Pollinators, S. K. Wawrzyczek, B. Bohman, S. L. Krauss, I. M. Butler, G. R. Flematti, K. Farnier, S. E. Hoebee, R. A. Davis, R. D. Phillips Aug 2026

Attraction Of Nocturnal Scarab Beetles By Unusual Floral Volatiles In A Banksia (Proteaceae) With Functionally Diverse Pollinators, S. K. Wawrzyczek, B. Bohman, S. L. Krauss, I. M. Butler, G. R. Flematti, K. Farnier, S. E. Hoebee, R. A. Davis, R. D. Phillips

Research outputs 2022 to 2026

Pollination by beetles has evolved multiple times in flowering plants but with relatively few plant species adapted specifically to pollination by scarab beetles (Coleoptera: Scarabaeidae). However, some plant species may produce floral scents and offer floral rewards that attract scarabs alongside other pollinator functional groups. In Banksia attenuata (Proteaceae), nocturnal observations led to the discovery of extensive floral visitation by beetles, alongside birds, mammals and diurnal insects. Given the distinctive melon-like floral scent of B. attenuata, we predicted long-distance attraction of beetles by chemical cues. We undertook floral visitor surveys aided by camera traps and video recordings, and quantified insect …


Differential Effects Of Physical Activity Interventions On Gross And Fine Motor Difficulties In Children With Autism Spectrum Disorder: Insights From A Multilevel Meta-Analysis With Moderator Analyses, Changhui Peng, Jinrong He, Kai Xu, Xueping Wu, Dandan Wang, Lei Zhang Aug 2026

Differential Effects Of Physical Activity Interventions On Gross And Fine Motor Difficulties In Children With Autism Spectrum Disorder: Insights From A Multilevel Meta-Analysis With Moderator Analyses, Changhui Peng, Jinrong He, Kai Xu, Xueping Wu, Dandan Wang, Lei Zhang

Research outputs 2022 to 2026

Background Difficulties in gross and fine motor skills negatively affect the healthy development of children with autism spectrum disorder (ASD), yet evidence for physical activity interventions (PAIs) remains limited and inconsistent. Therefore, this study aimed to investigate the differential effects of PAIs on gross and fine motor difficulties in children with ASD and to explore potential moderators. Methods Following PRISMA guidelines, empirical studies published from inception to April 21, 2026 were systematically searched across PubMed, Web of Science, Embase, the Cochrane Library, and SPORTDiscus. Effect sizes were synthesized using a three-level random-effects model and were expressed as Hedges’ g (g). …


Experimental Thermal-Hydraulic Performance Enhancement Of A Parabolic-Trough Solar Collector Using 3d-Printed Propeller-Shaped Turbulators, Shayan Pourhemmati, Barun Kumar Das, Majid Tolouei-Rad, Abdellah Shafieian Aug 2026

Experimental Thermal-Hydraulic Performance Enhancement Of A Parabolic-Trough Solar Collector Using 3d-Printed Propeller-Shaped Turbulators, Shayan Pourhemmati, Barun Kumar Das, Majid Tolouei-Rad, Abdellah Shafieian

Research outputs 2022 to 2026

This experimental study investigates the thermal-hydraulic performance of a parabolic trough collector (PTC) equipped with propeller-shaped turbulators, which were 3D printed and installed along the absorber tube to enhance convective heat-transfer by increasing flow mixing. Nine turbulator configurations were tested by varying the blade angle (β = 22.5° and 45°, and β = 67.5°) and the number of turbulators (Nt = 6, 12, and Nt = 18) over a Reynolds number range of 1000 to 6000. To ensure a rigorous and unbiased comparison, all experiments were conducted under identical operating conditions, including a constant inlet temperature and a constant Reynolds …


Plant-Based Diets, Ultra-Processed Foods, And Risks Of Mortality And Major Chronic Diseases: A Prospective Cohort Study, Alysha S. Thompson, Amy Jennings, Nicola P. Bondonno, Aedín Cassidy, Tilman Kühn Aug 2026

Plant-Based Diets, Ultra-Processed Foods, And Risks Of Mortality And Major Chronic Diseases: A Prospective Cohort Study, Alysha S. Thompson, Amy Jennings, Nicola P. Bondonno, Aedín Cassidy, Tilman Kühn

Research outputs 2022 to 2026

Background: Higher-quality plant-based diets (PBDs) are associated with lower risks of mortality and chronic disease, but whether ultra-processed food (UPF) content affects these associations remains unclear. We examined whether UPF content influences the relationship between plant-based dietary patterns and risks of mortality and major chronic diseases, accounting for nutrient quality. Methods: This prospective cohort study included 124,836 UK Biobank participants aged 40–70 years (recruited 2006–2010). Dietary intake was assessed using the Oxford WebQ 24-h recall. Four modified Plant-Based Diet Indices (PDIs) were derived to distinguish healthy (hPDI) and unhealthy (uPDI) patterns with high- and low-UPF content, using the Nova classification …


Post-Vaccination Confidence In Covid-19 Vaccines And Associated Determinants In Post-War Context Of Tigray, Northern Ethiopia: A Mixed-Methods Study, Genanew Kassie Getahun, Yohannes Addisu Wondimagegne, Alemayehu Deressa, Barkot Tamiru, Trhas Tadesse Berhe, Moges Mekonnen, Tsegay Hadgu, Znabu Hadush Kahsay, Mussie Alemayehu, Gebrehaweria Gebrekurstos, Joy Kenyi, Eshetu Girma, Finina Abebe Ware, Nardos Gelana, Menen Tsegaw, Eyob Ketema Bogale, Asaye Alamneh Gebeyehu Aug 2026

Post-Vaccination Confidence In Covid-19 Vaccines And Associated Determinants In Post-War Context Of Tigray, Northern Ethiopia: A Mixed-Methods Study, Genanew Kassie Getahun, Yohannes Addisu Wondimagegne, Alemayehu Deressa, Barkot Tamiru, Trhas Tadesse Berhe, Moges Mekonnen, Tsegay Hadgu, Znabu Hadush Kahsay, Mussie Alemayehu, Gebrehaweria Gebrekurstos, Joy Kenyi, Eshetu Girma, Finina Abebe Ware, Nardos Gelana, Menen Tsegaw, Eyob Ketema Bogale, Asaye Alamneh Gebeyehu

Research outputs 2022 to 2026

Introduction It is widely recognized that access to and utilization of health services are negatively impacted by war. These effects worsen particularly when combined with pandemics such as COVID-19. Therefore, this study aimed to assess adults' COVID-19 post-vaccination confidence in the conflict-affected region of Tigray, Northern Ethiopia. Methods The study employed a concurrent parallel mixed-methods design, combining a quantitative survey of 1599 adults and six key informant interviews and six focus group discussions. Survey participants were selected using a multistage cluster sampling technique, while qualitative participants were purposively sampled. Quantitative data were collected using a pre-tested, structured questionnaire administered via …


Source-Specific Nitrate And Nitrite Intake And Bladder Cancer: Findings From The Danish Diet, Cancer And Health Cohort, Dorit W. Erichsen, Cecilie Kyrø, Jörg Schullehner, Susanne Rosthøj, Catherine P. Bondonno, Liezhou Zhong, Ole Raaschou-Nielsen, Pratik Pokharel, Torben Sigsgaard, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Christina Dahl, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno Aug 2026

Source-Specific Nitrate And Nitrite Intake And Bladder Cancer: Findings From The Danish Diet, Cancer And Health Cohort, Dorit W. Erichsen, Cecilie Kyrø, Jörg Schullehner, Susanne Rosthøj, Catherine P. Bondonno, Liezhou Zhong, Ole Raaschou-Nielsen, Pratik Pokharel, Torben Sigsgaard, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Christina Dahl, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno

Research outputs 2022 to 2026

Introduction Nitrate and nitrite, present in ground and drinking water, as well as foods, may contribute to bladder cancer through the formation of carcinogenic N -nitrosamines. However, risk likely depends on both the source and endogenous nitrosating factors. Methods Among participants of the Danish Diet, Cancer, and Health Cohort (N = 54,610) with no history of cancer, source-specific nitrate and nitrite intakes (drinking water, plant sources, naturally occurring animal sources, and additive-permitted meat sources) were estimated from national water monitoring data and food frequency questionnaires using food databases. Bladder cancer cases were ascertained through the Danish Cancer Registry. Multivariable-adjusted Cox …


Basketball Players Jump And Maximal Strength Performance Improvements After French Contrast Training, Yiqing Xie, Yemin Han, Qing Du, Zhen Zhang, Rodrigo Ramirez-Campillo, Kai Xu Aug 2026

Basketball Players Jump And Maximal Strength Performance Improvements After French Contrast Training, Yiqing Xie, Yemin Han, Qing Du, Zhen Zhang, Rodrigo Ramirez-Campillo, Kai Xu

Research outputs 2022 to 2026

(1) Background: French contrast training (FCT) enhances sports performance, but its long-term efficacy in elite basketball players remains unclear. This study compared FCT and traditional strength training (TST) on jump performance and lower-limb strength.

(2) Methods: Sixteen elite basketball players (age 22.4 ± 1.4 years; 14 male, 2 female) were randomly assigned to 8 weeks of FCT (n = 8) or TST (n = 8). The TST protocol consisted of barbell back squat, barbell Bulgarian split squat, conventional deadlift, and barbell hip thrust (4 sets of 8, 6, 4, 4 repetitions at 80%, 95%, 90%, 90% of one-repetition maximum [1RM]; …


Dietary Patterns And Cognitive Decline In Older Adults: Findings From The Western Australia Memory Study, Carolina Blagojevic Castro, Samantha L. Gardener, Farzana Jahan, Juliana Chen, Belinda M. Brown, Ruey L. Loo, Kevin Taddei, Stephanie R. Rainey-Smith, Michael Weinborn, Ana Caroline R.Dos Reis, Manohar L. Garg, Ralph N. Martins, Hamid R. Sohrabi Aug 2026

Dietary Patterns And Cognitive Decline In Older Adults: Findings From The Western Australia Memory Study, Carolina Blagojevic Castro, Samantha L. Gardener, Farzana Jahan, Juliana Chen, Belinda M. Brown, Ruey L. Loo, Kevin Taddei, Stephanie R. Rainey-Smith, Michael Weinborn, Ana Caroline R.Dos Reis, Manohar L. Garg, Ralph N. Martins, Hamid R. Sohrabi

Research outputs 2022 to 2026

Background: Preventive strategies, including adherence to specific dietary patterns, have received increasing attention as approaches to reduce cognitive decline and dementia risk. However, findings remain inconsistent, partly due to differences in dietary assessment methods, cognitive outcomes, and THE consideration of genetic susceptibility factors such as apolipoprotein E (APOE) genotype.

Methods: This study examined associations between dietary patterns and longitudinal cognitive change in 185 older adults without dementia from the Western Australia Memory Study. Participants completed a food frequency questionnaire at baseline and underwent comprehensive neuropsychological assessments at baseline and up to five follow-up visits at 18-month intervals. Composite scores were …


Early-Onset Colorectal Cancer With Liver-Only Metastases: A Retrospective Cohort Study Integrating Prospectively Collected Real-World Clinical And Molecular Data From An Australian National Database (2009–2024) To Guide Treatment Planning, Savio G. Barreto, Christos S. Karapetis, Shahid Ullah, Matthew Burge, Susan Caird, Angus Campbell, Azim Jalali, Ross Jennens, Muhammad A. Khattak, Belinda Lee, Stephanie H. Lim, Shehara Mendis, Louise Nott, Timothy J. Price, Jeremy D. Shapiro, Jeanne Tie, Javier Torres, Colin Williams, Rachel Wong, Vanessa Wong, Peter Gibbs Aug 2026

Early-Onset Colorectal Cancer With Liver-Only Metastases: A Retrospective Cohort Study Integrating Prospectively Collected Real-World Clinical And Molecular Data From An Australian National Database (2009–2024) To Guide Treatment Planning, Savio G. Barreto, Christos S. Karapetis, Shahid Ullah, Matthew Burge, Susan Caird, Angus Campbell, Azim Jalali, Ross Jennens, Muhammad A. Khattak, Belinda Lee, Stephanie H. Lim, Shehara Mendis, Louise Nott, Timothy J. Price, Jeremy D. Shapiro, Jeanne Tie, Javier Torres, Colin Williams, Rachel Wong, Vanessa Wong, Peter Gibbs

Research outputs 2022 to 2026

Objective: To leverage the Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) registry (an Australian cancer database) to explore the ideal timing and sequence of therapies and the factors influencing these decisions in colorectal cancer (CRC) patients with liver-only metastases to inform contemporary decision-making and future trials.

Study Type: Retrospective registry-based cohort study using the TRACC registry.

Setting and Participants: Consecutive patients with liver-only metastatic CRC enrolled in the TRACC registry.

Main Outcome Measures: To explore cancer biology, intended treatment at presentation, actual treatment received and the resultant outcomes for early-onset CRC (EOCRC) (≤ 50 years) and late-onset CRC (LOCRC) …


Evaluating Echo2 Biochar As Sustainable Bitumen Binder Modifier In Road Pavements: High-Temperature Performance Characterisation, Adeel Iqbal, Nuha S. Mashaan, Themelina Paraskeva, Mohamed A. Shahin Aug 2026

Evaluating Echo2 Biochar As Sustainable Bitumen Binder Modifier In Road Pavements: High-Temperature Performance Characterisation, Adeel Iqbal, Nuha S. Mashaan, Themelina Paraskeva, Mohamed A. Shahin

Research outputs 2022 to 2026

The incorporation of bio-derived modifiers in bitumen binders presents a practical pathway toward sustainable, carbon-sequestering road pavement infrastructure. This study evaluates commercially produced ECHO2 softwood biochar as a modifier for Australian viscosity-graded C170 bitumen, combining microstructural, thermal, physical, and rheological characterization to assess its suitability as a high-temperature reinforcing modifier. In this study, biochar was incorporated at 3%, 6%, 9%, and 12% by weight, utilizing particles smaller than 75 µm to maximize interfacial interaction. Characterization via SEM-EDS, XRD, and TGA revealed a highly stable, carbon-rich, amorphous material with a rough, porous morphology, favourable for physical interlocking with the bitumen matrix. …


Exploring Traditional Breast Cancer Risk Genes Among Aboriginal And Torres Strait Islander Women, Katie Meehan, Leanne Pilkington, Azim Khan, Nicholas Pachter, Lisa Spalding, Ayeisha Milligan Armstrong, Cameron Redfern, Andrew Redfern Aug 2026

Exploring Traditional Breast Cancer Risk Genes Among Aboriginal And Torres Strait Islander Women, Katie Meehan, Leanne Pilkington, Azim Khan, Nicholas Pachter, Lisa Spalding, Ayeisha Milligan Armstrong, Cameron Redfern, Andrew Redfern

Research outputs 2022 to 2026

Background: Germline pathogenic variants in BRCA1/2 increase breast and ovarian cancer risk, but their prevalence in Aboriginal and Torres Strait Islander (herein referred to as Aboriginal) families has never been studied. Consequently, their contribution to breast cancer in this population is unknown.

Methods: This retrospective cohort study included 259 Aboriginal women and 789 age- and remoteness-matched non-Aboriginal women diagnosed with breast cancer (2001–2016). We assessed family history, genetic service referral and testing rates, and pathogenic variant rates in the context of testing access.

Results: Family history data were available for more Aboriginal than non-Aboriginal cases (46% vs. 34%, p < 0.001), with no difference in reported first-degree relatives with breast (22.5% vs. 22.4%, p = 0.98) or ovarian cancer (4.2% vs. 2.2%, p = 0.29). Similar proportions were referred to genetic services for testing eligibility (5.4% vs. 7.2%, p = 0.392). Of those referred, similar proportions were offered testing (86% vs. 81%, p = 0.66). Across the full cohort, BRCA1/2 pathogenic variants were detected in 0.77% of Aboriginal versus 2.4% of non-Aboriginal women (p = 0.127); any pathogenic gene variant was detected in 0.77% versus 3.0% (p = 0.039).

Conclusions: …


Leveraging Artificial Intelligence To Enhance Marine Biosecurity, Marnie L. Campbell, Chi T.U. Le, Jumana Abu-Khalaf, Craig D.H. Sherman Aug 2026

Leveraging Artificial Intelligence To Enhance Marine Biosecurity, Marnie L. Campbell, Chi T.U. Le, Jumana Abu-Khalaf, Craig D.H. Sherman

Research outputs 2022 to 2026

Marine biosecurity stands at the crossroads of innovation and necessity, with artificial intelligence (AI) offering promising tools to enhance risk assessment, surveillance, and response strategies for invasive species management. Despite the rapid growth of AI applications in marine science, there has been no comprehensive overview of its potential role in enhancing and supporting marine biosecurity. Our literature review aims to fill this gap, showing that AI use in this field remains limited and underdeveloped. Through our literature analysis, we identify key opportunities for AI research and innovation across the marine biosecurity continuum, while also highlighting both general and domain-specific challenges. …


Safety And Effectiveness Of Behavioural Activation For Chronic Pain: A Protocol For A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Fangyuan Zheng, Laura Hynes, Richard J. Gray, Irene Ngune, Jacqueline Sin, Martin Jones Aug 2026

Safety And Effectiveness Of Behavioural Activation For Chronic Pain: A Protocol For A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Fangyuan Zheng, Laura Hynes, Richard J. Gray, Irene Ngune, Jacqueline Sin, Martin Jones

Research outputs 2022 to 2026

Background/Objectives: Chronic pain is a prevalent and complex condition associated with substantial physical, psychological, and social burden. Behavioural activation (BA), a structured psychological intervention originally developed for depression, may be relevant to chronic pain through its focus on reducing behavioural avoidance and increasing engagement in meaningful activities. Although BA has been applied in studies involving people with chronic pain, the safety and effectiveness of BA in this population have not been comprehensively synthesised. This systematic review and meta-analysis will examine the safety and effectiveness of BA for people with chronic pain.


The Reliability And Validity Of Manual Palpation To Assess Lower Limb Arterial Occlusion Pressure In Older Adults, For Application In Blood Flow Restriction Exercise, Michael Beere, Isaac Selva Raj, Jeremiah J. Peiffer, Keith D. Hill, Peter K. Edwards, Belinda Brown, Brendan R. Scott Aug 2026

The Reliability And Validity Of Manual Palpation To Assess Lower Limb Arterial Occlusion Pressure In Older Adults, For Application In Blood Flow Restriction Exercise, Michael Beere, Isaac Selva Raj, Jeremiah J. Peiffer, Keith D. Hill, Peter K. Edwards, Belinda Brown, Brendan R. Scott

Research outputs 2022 to 2026

(A) Investigate test-retest reliability of posterior tibial pulse palpation to determine arterial occlusion pressure (AOP) and examine validity against hand-held Doppler ultrasound. (B) Investigate the suitability of using 130% systolic brachial blood pressure for prescribing cuff inflation pressure for blood flow restriction (BFR) exercise. Repeated measures, crossover design. Lower limb AOP was assessed in 20 adults ≥ 60 years using hand-held Doppler ultrasound and posterior tibial pulse palpation. Brachial systolic blood pressure (bSBP) was measured to predict cuff inflation pressures (bSBP130%). On three occasions > 24 hours apart, three AOP measurements were recorded by the same blinded rater to determine intra-rater …


Validated Near-Infrared Spectroscopy And Chemometric Modelling For Rapid Quantification Of Essential Oil Yield And Α/Β-Santalol In Santalum Album L., Muhammad Hassnain, Muhammad Rizwan Azhar Aug 2026

Validated Near-Infrared Spectroscopy And Chemometric Modelling For Rapid Quantification Of Essential Oil Yield And Α/Β-Santalol In Santalum Album L., Muhammad Hassnain, Muhammad Rizwan Azhar

Research outputs 2022 to 2026

The sandalwood industry remains constrained by destructive, time-intensive assays for essential oil (EO) yield, composition, moisture content, and wood fraction, which limit real-time decision-making. We report a unified near-infrared spectroscopy-artificial intelligence (NIRS-AI) platform for non-destructive analytics across the Santalum album L. value chain. Reflectance and transmittance spectra from solid matrices (disks, logs, chips, and powders), oils, ethanol extracts, and CID-derived emulsions were acquired using benchtop (400–2500 nm) and portable (900–1700 nm) spectrometers and calibrated against hydrodistillation, gas chromatography, extraction, and moisture assays. Advanced chemometric modelling using AI-based machine learning techniques, including regularised regression, ensemble learning, boosting algorithms, and neural networks, …


Wevit: Weight-Entangled Vision Transformers With Class-Specific Attention For Weakly Supervised Semantic Segmentation, Narges Saeedizadeh, Seyed Mohammad Jafar Jalali, Burhan Khan, Shady Mohamed Aug 2026

Wevit: Weight-Entangled Vision Transformers With Class-Specific Attention For Weakly Supervised Semantic Segmentation, Narges Saeedizadeh, Seyed Mohammad Jafar Jalali, Burhan Khan, Shady Mohamed

Research outputs 2022 to 2026

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task in computer vision, as it relies on limited supervision to generate precise object localization maps, often using Class Activation Maps (CAMs). Traditional methods struggle with balancing localization accuracy and scalability due to their reliance on fixed network architectures and handcrafted strategies. Neural Architecture Search (NAS), despite its proven success in optimizing network designs across tasks, has not yet been explored in WSSS due to the need for efficient weight sharing. To address these limitations, we propose WEViT, a novel framework that integrates NAS with transformers to optimize network architectures and generate …


Experimental And Molecular Dynamic Simulation Assessment Of H2/Brine/Cement Interfacial Interactions During Underground Hydrogen Storage, Nurudeen Yekeen, Sikiru, Ahmed Al-Yaseri, Berihun Mamo Negash Aug 2026

Experimental And Molecular Dynamic Simulation Assessment Of H2/Brine/Cement Interfacial Interactions During Underground Hydrogen Storage, Nurudeen Yekeen, Sikiru, Ahmed Al-Yaseri, Berihun Mamo Negash

Research outputs 2022 to 2026

Cement is widely used as a structural and sealing material to ensure hydrogen containment in geological formations. However, the influence of H2–brine–cement wettability and H2–brine interfacial tension (IFT) on the integrity and sealing efficiency of cemented caprocks remains poorly understood. Furthermore, previous studies provide limited insights into hydrogen adsorption and sorption behavior under subsurface storage conditions. In this study, wettability and IFT of H2–brine–cement systems were experimentally measured at pressures of 500–1000 psi and temperatures of 25–50 °C to evaluate hydrogen migration, trapping, and the performance of cemented seals. Molecular dynamics simulations were conducted at pressures of 500–3000 psi and …


Characterising Manual Dexterity, Motor Cortex Neuroplasticity, And Intracortical Inhibition Long After Burn Injury, Grant S. Rowe, Alecia Wood, Mark Fear, Dale W. Edgar, Aleksandra Miljevic, Tyler Osborne, Natalie Morellini, Merrilee Needham, Ann Maree Vallence, Fiona Wood Aug 2026

Characterising Manual Dexterity, Motor Cortex Neuroplasticity, And Intracortical Inhibition Long After Burn Injury, Grant S. Rowe, Alecia Wood, Mark Fear, Dale W. Edgar, Aleksandra Miljevic, Tyler Osborne, Natalie Morellini, Merrilee Needham, Ann Maree Vallence, Fiona Wood

Research outputs 2022 to 2026

Purpose: Persistent motor dysfunction after burn injury may be due to altered motor cortex and corticospinal tract function. This study examined manual dexterity, motor cortex neuroplasticity, and intracortical inhibition in former burn patients 1–3 years after minor injury (<10% TBSA). Method: Thirty former burn patients (TBSA: 0.78 ± 1.08%) and 30 non-injured controls participated. Manual dexterity was assessed using the Purdue Pegboard. Transcranial magnetic stimulation (TMS) was used to measure motor cortex excitability (motor evoked potential [MEP] amplitude) and short- and long-interval intracortical inhibition (SICI, LICI) before and after paired-associative stimulation (PAS) to induce neuroplasticity. Results: Former burn patients performed worse than controls on the bimanual assembly subtest of the Purdue Pegboard. PAS did not induce changes in MEP amplitude but increased LICI in both burn patients and control participants. In burn patients, baseline LICI was related to bimanual performance differently than controls. Conclusions: These findings suggest poorer bimanual motor function persists after minor burns, and differences in the association between inhibition and bimanual dexterity between burn and control groups. Further research should explore whether targeting motor cortex inhibitory circuits can improve motor performance following burn injury