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To The Torus And Beyond: An X-Ray Study Of Agn Tori Morphology, Andrealuna Pizzetti

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Active Galactic Nuclei (AGN) are among the Universe's most energetic and powerful objects, fueled by an accreting supermassive black hole (SMBH) at the host galaxy's center, surrounded by a toroidal structure of dusty gas. Ultraviolet photons arising from the accretion disk get up-scattered to X-rays via inverse Compton scattering by hot electrons close to the accretion disk. Being produced in the very center of the AGN, X-ray photons are powerful messengers that probe the physics of the accretion system and the matter in the surroundings. The torus, formerly considered homogeneous, appears to be a more complex structure of clouds with …

Additive Manufacturing With Bioresorbable Polymers: Process-Structure-Property Relationships For Biomimetic Tissue Scaffolds, Clayton Joseph Culbreath

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Tissue engineering has a base requirement of scaffold structures to support cell growth, proliferation, and regeneration. However, attempts to use artificial scaffold structures have often fallen short of clinical needs to justify the change away from the established, biologic-based current standard of care. Based on the limited number of successful tissue scaffolds produced by material extrusion modes of additive manufacturing, fused filament 3d printing and electrospinning, critical design specifications for a tissue scaffold are six minimum requirements: 1) biocompatibility, 2) porosity, 3) mechanical properties, 4) bioresorbable medical grade materials, 5) bioactivity, and 6) appropriately scaled production methods compliant with medical …

Exploring Novel Nutrient Acquisition Mechanisms For Maintaining Energy Metabolism In Toxoplasma Gondii, Melanie Key

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Toxoplasma gondii is an infectious intracellular parasite that establishes infection within various mammalian hosts, including humans. Toxoplasma infects approximately one-third of the global population, making it an impactful pathogen of study. T. gondii is the causative agent of toxoplasmosis, an opportunistic infection that causes severe illness or fatality in immunocompromised individuals or pregnant women. The parasite possesses a very effective invasion strategy, allowing it to cross different tissue types to disseminate infection across the placental and blood-brain barrier. Although there are a few treatments for acute toxoplasmosis, these drugs can produce adverse side effects. These options are not effective against …

Machine Learning Assisted Discovery Of High-Performance Perovskites For Hydrogen Production, Ximei Zhai

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Hydrogen has significantly contributed to the global energy transition as a clean energy carrier. However, traditional hydrogen production involves energy-intensive processes with heavy carbon emissions. High-temperature water splitting to generate hydrogen has become a promising route for clean hydrogen production. Directly utilizing concentrated solar heat to perform solar thermochemical hydrogen (STCH) production is considered one of the most eco-friendly hydrogen production options. At the same time, high-temperature electrolysis in protonic ceramic electrolysis cells (PCECs) can efficiently utilize intermittent and cost-effective renewable electricity to produce hydrogen. Perovskite oxides with good redox capability and tolerance for oxygen deficiency are considered the most …

Volatile Crystalline Semiconductor Core Fibers, Thomasina Zaengle

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Optical fibers play critical roles across many facets of everyday life from communications to e-commerce to sensing and security. The ubiquity of optical fibers arises from their intrinsic clarity and, as glasses, their ability to be thermally drawn at high speeds over long distances when suitably heated about their glass transition temperature. Sixteen years ago, the first thermally drawn crystalline core fibers were fabricated using the molten core method, whereby a melt is confined within a glass capillary tube that is then drawn to fiber. This opened the door to crystalline semiconductor core fibers, which are now the backbone of …

Tin-Silver As A Novel Biodegradable Metallic Biomaterial, Charley Goodwin

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The Essure device is a non-hormonal, minimally-invasive, permanent female sterilization implant, removed from the market due to an increase in adverse events, hypothesized to be caused by corrosion of the Sn-Ag component of the implant. The goals of this dissertation were to first develop implant retrieval methods for Essure devices and surrounding tissue, documenting signs of degradation and metallic degradation products, then to characterize the electrochemical behavior of Sn-Ag in biologically representative environments and finally, to assess the biological interaction of Sn-Ag. Retrieval analyses developed successful methods, qualifying the degree of corrosion, primarily of the Sn-Ag component and finding Sn …

With Great Power: Using Comics To Facilitate Discussion Of Systemic Oppression In Higher Education Literature Classes, Keri Crist-Wagner

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Undergraduate student participation in general education classes constitutes a point of struggle for many educators, especially when it comes to lessons centered around systems of oppression like racism, sexism, or heterosexism. Using both constructivism and counter storytelling as theoretical frameworks, this multi-method phenomenological case study explored the experiences of undergraduate honors students in a semester long general education literature class. The purpose of this study was to 1) explore how comics can be used as a pedagogical tool in higher education classrooms to facilitate discussion of systems of oppression, 2) assess the ways in which students interacted with comics, and …

Inviting The Public Into Wildlife Research: Does Participation In Research Projects That Facilitate Interactions With Local Species Change Feelings Of Connection?, Seth Gibbons

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For many reasons, humans are less connected to nature. Research shows that people who feel more connected to nature are more likely to have pro-environmental intentions. One possible way to strengthen the human-nature connection is to involve the public in wildlife research, exposing them to local wildlife in a way that highlights science. This dissertation investigates two such projects, the 2019 Clemson Barred Owl Project and the Trout in the Classroom (TIC) program, to understand the effects of interacting with local species through wildlife research.

Interviews were conducted with participants and the lead researcher of the Clemson Barred Owl Project …

Essays On Environmental And Natural Resource Economics, Annaliese R. Winton

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This dissertation explores how markets and producers respond to environmental risks that are becoming more severe due to climate change. It is comprised of two essays that empirically quantify the economic impacts of two water-related risks: storm surge flooding and groundwater depletion. In the first chapter, I estimate the price differentials associated with single-family homes in hurricane evacuation zones in Miami-Dade County, Florida, using two near-miss hurricanes as a source of exogenous information. The second chapter estimates the impacts of groundwater depletion, as captured through declining well capacity, on irrigation decisions in the Colorado portion of the Republican River Basin.

Mammary Epithelial Cell Derived Extracellular Vesicles Influence Tumorigenic Phenotype Suppression In Her2-Positive Breast Cancer Cells, Brenda Okereke

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On a global scale, breast cancer remains the most commonly diagnosed cancer in the world. In 2020 alone, there were over 2.3 million new cases of breast cancer seen and a total of 685,000 deaths globally, this represents 16% or 1 in every 6 cancer deaths seen in women. By 2040 it is projected that the breast cancer burden will rise by over 40% to exceed 3 million new cases a year. Further understanding of the underlying biology and mechanisms behind tumor progression and breast cancers such as HER2+ breast cancer would allow for new therapeutic treatment targets to emerge. …

Mesenchymal Stromal Cell Response To Degenerated Intervertebral Disc-Like Ph, Kyle Cannon

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Intervertebral disc degeneration (IVDD) has become increasingly prevalent and is a common contributing factor to low back pain. There are currently no clinical treatment options for IVDD that alleviate the symptoms of IVDD while simultaneously promoting repair of IVD tissue. One treatment option being explored is intradiscal administration of mesenchymal stromal cells (MSCs). However, the microenvironment of the degenerating IVD places significant stress on both native IVD cells and implanted cells. There are several questions that need to be addressed which may help further inform the development of efficacious intradiscal MSC therapies for IVDD. These questions include: 1) Do MSCs …

Crystalline Colloidal Arrays: Exploring Light-Matter Interactions, Haley W. Jones

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Understanding and manipulating quantum light-matter interactions, especially in the context of nanostructured environments, is highly critical for technological progress and inventive solutions in the fields of telecommunications, energy-efficient lighting, and cutting-edge quantum computing technologies. The fundamental interactions of photons with a surrounding environment directly impact the performance and efficiency of devices such as lasers, light-emitting diodes (LEDs), and quantum computing elements, which leverage the unique properties of confined structured environments. Since the late 1980s, the connection between a structured environment and the decay kinetics of an embedded fluorophore has been a highly debated and unresolved topic in the literature. More …

Design, Fabrication, And Characterization Of Advanced High-Power Single-Mode 9xxnm Semiconductor Lasers, Xiaolei Zhao

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This thesis presents the comprehensive design, fabrication, and demonstration of advanced high-power, high-efficiency single-mode semiconductor lasers operating at a wavelength of 9xxnm. We begin with the design of the laser epitaxial structure, serving as the cornerstone for achieving high-power high-efficiency lasers. Our methodology integrates a semi-analytical calculation model, which accounts for Longitudinal Spatial Hole Burning (LSHB) and Two-Photon Absorption (TPA) effects, facilitating a thorough exploration of how design parameters influence output power and conversion efficiency. This approach offers an effective and time-efficient epitaxial structure optimization strategy compared to conventional full 3D simulation models.

Subsequently, we demonstrate high-power, high-efficiency ridge waveguide …

Understanding The Experiences Of Para-Collegiate Student- Athletes: A Mixed Methods Study, Derek Whaley

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Experiences are the impressions developed through gaining, using, fostering, and sometimes disposing of a service or product. Recent years have shown an ongoing emphasis placed on experiences and their impacts; one of particular interest for this study are the experiences of para-collegiate student-athletes. Using the Experience Type Framework (ETF) and the Extraordinary Impact Scale (EIS), the purpose of this study was to understand the experience of involvement in intercollegiate sports among adaptive student-athletes. This study employed an explanatory sequential mixed methods design, using quantitative and qualitative data to understand the adaptive student-athlete experience. Phase I (n = 30) used the …

Structure And Dynamics Of Complex Fluids Formed By Ionomers: Experimental-Computational Insight, Chathurika Kosgallana

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The current study focuses on understanding the effect of clustering on the structure, dynamics, and response of ionomers in melts and solutions using neutron scattering methods combined with atomistic large-scale molecular dynamics (MD) simulations.

Ionizable polymers are used in a wide range of applications, such as in clean energy and biotechnology, where ion transport is integral to the application. Ionizable groups drive cluster formation and often become the dominating force in determining the structure and dynamics of these polymers.

The work consists of five studies. The first study probes the structure of sulfonated polystyrene in toluene solutions tweaked by the …

Connecting Genotype And Phenotype: Investigating The Functional Morphology And Molecular Architecture That Influences Craniofacial Divergence Using Lake Malawi Cichlid Fishes, Leah Delorenzo

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Connecting genotype and phenotype to better understand how species evolve has been a goal of evolutionary developmental biologists over the last 50 years. This dissertation aims to connect genotype and phenotype of the craniofacial skeleton within the adaptive radiation of Lake Malawi cichlids to fortify our understanding of the functional, genetic, and epigenetic factors that contribute to craniofacial divergence. I start with a functional approach using 2D geometric morphometrics to assess craniofacial shape across the Lake Malawi cichlid radiation to bolster our knowledge of the bone phenotypes that are important to niche specialization and are functionally relevant. Next, I use …

Using Improvement Science And A Co-Teaching Model To Increase The Effects Of Evidence-Based Reading Intervention For High School Students Reading Below Grade Level Proficiency, Ashley Vaughn

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I conducted a single instrumental case study to address the problem of practice in which approximately one-third of students entering the ninth grade for the 2019-2020 school year in the study school district were reading below grade level proficiency. I chose an instrumental case study method because it allows for an in-depth examination of a situation within its real-life context. I opted for this approach because I sought to understand the problem of practice deeply and generate recommendations for practical application. By focusing on a single case, I could thoroughly explore the intricacies of the subject matter, providing valuable insights …

Electrode Engineering For Enhanced Performance And Low-Cost Redox Flow Batteries, Abena Williams

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Carbon "Quantum" Dots: Structures, Properties, And Issues, Weixiong Liang

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Carbon dots (CDots) are small carbon nanoparticles (CNPs) with effective surface passivation. The effective passivation has been achieved by the surface functionalization of pre-existing CNPs with organic molecules, mostly molecules containing primary or secondary amine moieties. In the studies highlighted in this dissertation, CNPs were functionalized by selected organic molecules, including especially the use of radical addition reactions, to generate CDots with strong absorption and bright fluorescence emissions. A good demonstration of the approach was the N-ethylcarbazole (NEC) radical addition to CNPs under microwave irradiation. Spectroscopy and microscopy methods were employed to characterize the resulting NEC-CDots, and the results …

State Crop Pest Committee Minutes, Clemson Board Of Trustees, 2024 April 17, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Student Affairs Committee, 2024 April 4, Clemson University Board Of Trustees

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No abstract provided.

Clemson University Board Of Trustees, Compensation Committee, 2024 April 5, Clemson University Board Of Trustees

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No abstract provided.

Clemson University Board Of Trustees, Breakfast Minutes, 2024 April 5, Clemson University Board Of Trustees

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Clemson University Board Of Trustees, Full Minutes, 2024 April 5, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Executive And Audit Committee, 2024 April 5, Clemson Univeristy Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Research And Economic Development Committee, 2024 April 4, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Institutional Advancement Committee, 2024 April 4, Clemson University Board Of Trustees

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No abstract provided.

Clemson University Board Of Trustees, Finance And Facilities Committee, 2024 April 4, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Educational Policy Committee, 2024 April 3, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Agriculture And Natural Resources Committee, 2024 April 3, Clemson University Board Of Trustees

Minutes

No abstract provided.