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The Tiger Vol. 106 Issue 5 2012-02-17, Clemson University

Tiger Newspapers

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The Tiger Vol. 106 Issue 4 2012-02-10, Clemson University

Tiger Newspapers

No abstract provided.

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Predicting The Physiological Performance Of Ectotherms In Fluctuating Thermal Environments, Michael W. Sears, A C. Niehaus, M J. Angilletta, C E. Franklin, R S. Wilson

Publications

Physiological ecologists have long sought to understand the plasticity of organisms in environments that vary widely among years, seasons and even hours. This is now even more important because human-induced climate change is predicted to affect both the mean and variability of the thermal environment. Although environmental change occurs ubiquitously, relatively few researchers have studied the effects of fluctuating environments on the performance of developing organisms. Even fewer have tried to validate a framework for predicting performance in fluctuating environments. Here, we determined whether reaction norms based on performance at constant temperatures (18, 22, 26, 30 and 34°C) could be …

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Analyzing Effects Of Naturally Occurring Missense Mutations, Zhe Zhang, Maria A. Miteva, Lin Wang, Emil Alexov

Publications

Single-point mutation in genome, for example, single-nucleotide polymorphism (SNP) or rare genetic mutation, is the change of a single nucleotide for another in the genome sequence. Some of them will produce an amino acid substitution in the corresponding protein sequence (missense mutations); others will not. This paper focuses on genetic mutations resulting in a change in the amino acid sequence of the corresponding protein and how to assess their effects on protein wild-type characteristics. The existing methods and approaches for predicting the effects of mutation on protein stability, structure, and dynamics are outlined and discussed with respect to their underlying …

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Bl Lacertae Objects Beyond Redshift 1.3 - Uv-To-Nir Photometry And Photometric Redshift For Fermi/Lat Blazars, A. Rau, P. Schady, J. Greiner, M. Salvato, M. Ajello, E. Bottacini, N. Gehrels, P.M. J. Afonso, J. Elliott, R Filgas, D A. Kann, S Klose, T Krühler, M Nardini, A Nicuesa Guelbenzu, F Olivares E., A Rossi, V Sudilovsky, A C. Updike, Dieter H. Hartmann

Publications

Context.Observations of the γ -ray sky with Fermi led to signiﬁcant advances towards understanding blazars, the most extreme classof Active Galactic Nuclei. A large fraction of the population detected by Fermi is formed by BL Lacertae (BL Lac) objects, whosesample has always suﬀ ered from a severe redshift incompleteness due to the quasi-featureless optical spectra.Aims.Our goal is to provide a signiﬁcant increase of the number of conﬁrmed high-redshift BL Lac objects contained in the 2 LACFermi/LAT cataloge.Methods.For 103 Fermi/LAT blazars, photometric redshifts using spectral energy distribution ﬁtting have been obtained. The pho-tometry includes 13 broad-band ﬁlters from the far ultraviolet …

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Cxom31 J004253.1+411422: The First Ultraluminous X-Ray Transient In M 31, A. Kaur, M. Henze, F. Haberl, W. Pietsch, J. Greiner, A. Rau, Dieter H. Hartmann, G. Sala, M. Hernanz

Publications

Context. We seek clariﬁcation of the nature of X-ray sources detected in M 31. Here we focus on CXOM31 J004253.1+411422, the brightness of which suggests that it belongs to the class of ultraluminous X-ray sources. Aims. We determine the X-ray properties of sources detected in the XMM-Newton/Chandra monitoring program. We investigate spectral properties and search for periodic or quasi-periodic oscillations. Methods. A multicomponent model was applied to the spectra obtained from XMM-Newton data to evaluate the relative contributions from thermal and nonthermal emission. The time dependence of this ratio was evaluated over a period of forty days. We simultaneously ﬁt …

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Ice Research News, Vol. 2, No. 1 - February 2012, Clemson University

ICE Research News (Biannual Newsletter)

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Nested Canalyzing Depth And Network Stability, Lori Layne, Elena Dimitrova, Matthew Macauley

Publications

We introduce the nested canalyzing depth of a function, which measures the extent to which it retains a nested canalyzing structure. We characterize the structure of functions with a given depth and compute the expected activities and sensitivities of the variables. This analysis quantifies how canalyzation leads to higher stability in Boolean networks. It generalizes the notion of nested canalyzing functions (NCFs), which are precisely the functions with maximum depth. NCFs have been proposed as gene regulatory network models, but their structure is frequently too restrictive and they are extremely sparse. We find that functions become decreasingly sensitive to input …

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The Tiger Vol. 106 Issue 2 2012-01-27, Clemson University

Tiger Newspapers

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4-H Science: Evaluating Across Sites To Critically Examine Training Of Adult Facilitators, Pamela Larson Nippolt

Journal of Youth Development

As 4-H Youth Development focuses on developing and delivering high quality STEM learning experiences, the issues related to the preparation of the adults who facilitate learning with youth are important to address. This paper outlines a five-state pilot project funded by the 3M Foundation to test a model for training adult facilitators. The findings from this study raise questions about how non-formal educational programs involve and mobilize adult facilitators to work with youth in STEM-related learning when the emphasis is not only on engaging young people, but also on deepening their thinking and learning about engineering phenomena, in this case …

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A Goal Setting Intervention Positively Impacts Adolescents’ Dietary Behaviors And Physical Activity Self-Efficacy, Mical Kay Shilts, Marilyn S. Townsend

Journal of Youth Development

The efficacy of a youth development intervention on improving eating and physical activity(PA) self-efficacy, goal attainment scaling, goal effort, and behaviors was examined in a repeated measures, quasi-experimental field trial. Ethnically diverse students (n=64) from a low-income middle school participated in the 10-session intervention driven by the Social Cognitive Theory with a Goal Setting Theory emphasis. Participants, 13-14 years old, made significant changes in dietary behaviors ( P=0.03) and PA self-efficacy (P=0.02) after receiving the intervention. Self-efficacy did not mediate dietary behavior change but did mediate the small changes made in PA. Goal effort was not a mediator of behavior …

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Common Data Set 2011-2012, Clemson University

Common Data Sets

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The Tiger Special Issue Spring 2012, Clemson University

Tiger Newspapers

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Loft: The Observatory For X-Ray Timing, M. Feroci, J. W. Den Herder, E. Bozzo, D. Barret, S. Brandt, M. Hernanz, M. Van Der Klis, M. Pohl, A. Santangelo, L Stella, A Watts, J Wilms, S Zane

Publications

The LOFT mission concept is one of four candidates selected by ESA for the M3 launch opportunity as Medium Size missions of the Cosmic Vision programme. The launch window is currently planned for between 2022 and 2024. LOFT is designed to exploit the diagnostics of rapid X-ray flux and spectral variability that directly probe the motion of matter down to distances very close to black holes and neutron stars, as well as the physical state of ultradense matter. These primary science goals will be addressed by a payload composed of a Large Area Detector (LAD) and a Wide Field Monitor …

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Measuring The Stellar Accretion Rates Of Herbig Ae/Be Stars, Brian Donehew, Sean D. Brittain

Publications

The accretion rate of young stars is a fundamental characteristic of these systems.While accretion onto T Tauri stars has been studied extensively, little work has been done on measuring the accretion rate of their intermediate-mass analogs, the Herbig Ae/Be stars. Measuring the stellar accretion rate of Herbig Ae/Bes is not straightforward both because of the dearth of metal absorption lines available for veiling measurements and the intrinsic brightness of Herbig Ae/Be stars at ultraviolet wavelengths where the brightness of the accretion shock peaks. Alternative approaches to measuring the accretion rate of young stars by measuring the luminosity of proxies such …

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Manufacturing Process Modeling And Application To Intelligent Control, M. Laine Mears, Parakshit Mehta, Mathew Kuttolamadom, Carlos Montes, Joshua Jones, Wesley Salandro, Drew Werner

Publications

This paper reviews the major findings and intellectual contributions made over the past five years through research in the laboratory of Dr. Laine Mears at Clemson University. The focus of the laboratory’s work is in modeling of traditional and novel manufacturing processes, and application of such models to process control through model-based control strategies. Introducing intelligence to the manufacturing process through physical descriptions of the phenomena being controlled allows for more precise control as compared with reactive systems or those with simple feed-forward control schemes. For traditional processes, new approaches to process characterization allow for more precise control. For novel …

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Wycinanki: Production Of A Non-Photorealistic Rendered Short Film, Irena Rindos

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Animals have traditionally occupied a special role in human culture and media, and are also often the focus of today's computer-animated films. The computer graphics (CG) short, Wycinanki, examines the human-animal bond through the story of a woman who rescues animals in Poland. Additionally, Wycinanki draws on the cultural history of its protagonist with its unique paper-cut render style. The goal of this film is to engage viewers and enhance the staying power of the film's message via a compelling story and visuals.
A significant amount of environment and character development and testing was necessary to translate the 2D art …

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Extending Origami Technique To Fold Forming Of Sheet Metal Products, Ala Qattawi

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This dissertation presents a scientific based approach for the analysis of folded sheet metal products. Such analysis initializes the examination in terms of topological exploration using set of graph modeling and traversal algorithms. The geometrical validity and optimization are followed by utilizing boundary representation and overlapping detection during a geometrical analysis stage, in this phase the optimization metrics are established to evaluate the unfolded sheet metal design in terms of its manufacturability and cost parameters, such as nesting efficiency, total welding cost, bend lines orientation, and maximum part extent, which aides in handling purposes. The proposed approach evaluates the design …

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Developing Hybrid Approaches To Predict Pka Values Of Ionizable Groups, Shawn Witham, Kemper Talley, Lin Wang, Zhe Zhang, Daquan Gao, Wei Yang, Emil Alexov

Publications

Accurate predictions of pKa values of titratable groups require taking into account all relevant processes associated with the ionization/deionization. Frequently, however, the ionization does not involve significant structural changes and the dominating effects are purely electrostatic in origin allowing accurate predictions to be made based on the electrostatic energy difference between ionized and neutral forms alone using a static structure. On another hand, if the change of the charge state is accompanied by a structural reorganization of the target protein, then the relevant conformational changes have to be taken into account in the pKa calculations. Here we report a hybrid …

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Progress In The Prediction Of Pka Values In Proteins, Emil Alexov, Ernest L. Mehler, Nathan Baker, Antonio Baptista, Yong Huang, Francesca Milletti, Jens Erik Nielsen, Damien Farrell, Tommy Carstensen, Mats H.M. Olsson, Jana K. Shen, Jim Warwicker, Sarah Williams, J Michael Word

Publications

The pK_a-cooperative aims to provide a forum for experimental and theoretical researchers interested in protein pK_a values and protein electrostatics in general. The first round of the pK_a-cooperative, which challenged computational labs to carry out blind predictions against pK_as experimentally determined in the laboratory of Bertrand Garcia-Moreno, was completed and results discussed at the Telluride meeting (July 6–10, 2009). This article serves as an introduction to the reports submitted by the blind prediction participants that will be published in a special issue of PROTEINS: Structure, Function and Bioinformatics. …

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Lithium In The Upper Centaurus Lupus And Lower Centaurus Crux Subgroups Of Scorpius-Centaurus, Eric J. Bubar, Marc Schaeuble, Jeremy R. King, Eric E. Mamajek, John R. Stauffer

Publications

We utilize spectroscopically derived model atmosphere parameters and the Li i λ6104 subordinate line and the λ6708 doublet to derive lithium abundances for 12 members of the Upper Centaurus Lupus and Lower Centaurus Crux subgroups of the Scorpius–Centaurus OB Association. The results indicate any intrinsic Li scatter in our 0.9–1.4 M stars is limited to ∼0.15 dex, consistent with the lack of dispersion in 1.0 M stars in the 100 Myr Pleiades and 30–50 Myr IC 2391 and 2602 clusters. Both ab initio uncertainty estimates and the derived abundances themselves indicate that the λ6104 line yields abundances with equivalent or …

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Clemson Commencement Program, December 2011, Clemson University

Clemson Commencement Programs

No abstract provided.

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An Investigation Of The Application Of Phase Change Materials In Practical Thermal Management Systems, David Ewing

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This work investigates the application of alternative cooling techniques to thermal management. In the first section, this work presents models and extensive simulation studies on an alternative cooling strategy based upon phase change materials (PCMs) for the thermal management system of a LED headlight assembly. These studies have shown that properly chosen PCMs, when suspended in metal foam matrices, increased the thermal conductivity of the PCM. The increased thermal conductivity can enhance the cooling characteristics of a practical thermal management system for a LED headlight system. To further enhance the advantages of using PCMs, nanoparticle enhanced fluids (nanofluids) are desirable …

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An Examination Of Variables Which Influence High School Students To Enroll In An Undergraduate Engineering Or Physical Science Major, Christopher Porter

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The purpose of this study was to examine the variables which influence a high school student to enroll in an engineering discipline versus a physical science discipline. Data was collected utilizing the High School Activities, Characteristics, and Influences Survey, which was administered to students who were freshmen in an engineering or physical science major at an institution in the Southeastern United States. A total of 413 students participated in the survey.
Collected data were analyzed using descriptive statistics, two-sample Wilcoxon tests, and binomial logistic regression techniques. A total of 29 variables were deemed significant between the general engineering and physical …

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A Formal Representation Of Mechanical Functions To Support Physics-Based Computational Reasoning In Early Mechanical Design, Chiradeep Sen

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The lack of computational support to the conceptual phase of mechanical engineering design is well recognized. Function-based modeling and thinking is widely recommended in design texts as useful means for describing design concepts and using them in tasks such as solution search, problem decomposition, and design archival. Graph-based function structure models that describe a product as a network of transformative actions of material, energy, and information, are discussed as a potential tool for this purpose, but in the current state of the art, function structures are not formalized as a computational representation. Consequently, no computer tool exists with which a …

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Computational Approaches To Understand Phenotypic Structure And Constitutive Mechanics Relationships Of Single Cells, Scott Wood

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The goal of this work is to better understand the relationship between the structure and function of biological cells by simulating their nonlinear mechanical behavior under static and dynamic loading using image structure-based finite element modeling (FEM). Vascular smooth muscle cells (VSMCs) are chosen for this study due to the strong correlation of the geometric arrangement of their structural components on their mechanical behavior and the implications of that behavior on diseases such as atherosclerosis.
VSMCs are modeled here using a linear elastic material model together with truss elements, which simulate the cytoskeletal fiber network that provides the cells with …

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Fluid Mud Underflows In Coastal Dredge Disposal, Mijanur Chowdhury

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This manuscript presents the results of a thorough theoretical and experimental investigation on fluid mud underflows generated in a typical coastal dredge disposal operation. The main goal of this investigation is to understand the propagation dynamics of fluid mud underflows that depends upon a number of factors, including: concentrations, rheological properties and released configurations of fluid mud. Laboratory experiments were conducted with different initial fluid mud concentrations in three different experimental set-ups: rectangular flume for constant volume release, rectangular flume for constant flux release, and a square pool for radial constant flux release of fluid mud. The experiments in the …

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Bases And Applications Of Riemann-Roch Spaces Of Function Fields With Many Rational Places, Justin Peachey

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Algebraic geometry codes are generalizations of Reed-Solomon codes, which are implemented in nearly all digital communication devices. In ground-breaking work, Tsfasman, Vladut, and Zink showed the existence of a sequence of algebraic geometry codes that exceed the Gilbert-Varshamov bound, which was previously thought unbeatable. More recently, it has been shown that multipoint algebraic geometry codes can outperform comparable one-point algebraic geometry codes. In both cases, it is desirable that these function fields have many rational places. The prototypical example of such a function field is the Hermitian function field which is maximal. In 2003, Geil produced a new family of …

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Mechanical And Modular Verification Condition Generation For Object-Based Software, Heather Harton

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The foundational goal of this work is the development of mechanizable proof rules and a verification condition generator based on those rules for modern software. The verification system will be modular so that it is possible to verify the implementation of a component relying upon only the specifications of underlying components that are reused. The system must enable full behavioral verification. The proof rules used to generate verification conditions (VCs) of correctness must be amenable to automation. While automation requires software developers to annotate implementations with assertions, it should not require assistance in the proofs. This research has led to …

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Modification And Characterization Of Fluorescent Conjugated Polymer Nanoparticles For Single Molecule Detection, Yueli Zheng

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Single molecule tracking using fluorescent dye or nanoparticle labels has emerged as a useful technique for probing biomolecular processes. Considerable interest arises in the development of nanoparticle labels with brighter fluorescence in order to improve the spatial and temporal resolution of single molecule detection and to facilitate the application of single molecule detection methods to a wider range of intracellular processes. The McNeill laboratory recently reported that conjugated polymer nanoparticles exhibit fluorescence cross-sections roughly 10-100 times higher than other luminescent nanoparticles of similar size, excellent photostability (2.2×108 photons emitted per nanoparticle prior to photobleaching), and saturated emission rates roughly 100 …

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Full-Text Articles in Entire DC Network

The Tiger Vol. 106 Issue 5 2012-02-17, Clemson University

Tiger Newspapers

The Tiger Vol. 106 Issue 4 2012-02-10, Clemson University

Tiger Newspapers

Predicting The Physiological Performance Of Ectotherms In Fluctuating Thermal Environments, Michael W. Sears, A C. Niehaus, M J. Angilletta, C E. Franklin, R S. Wilson

Publications

Analyzing Effects Of Naturally Occurring Missense Mutations, Zhe Zhang, Maria A. Miteva, Lin Wang, Emil Alexov

Publications

Publications

Cxom31 J004253.1+411422: The First Ultraluminous X-Ray Transient In M 31, A. Kaur, M. Henze, F. Haberl, W. Pietsch, J. Greiner, A. Rau, Dieter H. Hartmann, G. Sala, M. Hernanz

Publications

Ice Research News, Vol. 2, No. 1 - February 2012, Clemson University

ICE Research News (Biannual Newsletter)

Nested Canalyzing Depth And Network Stability, Lori Layne, Elena Dimitrova, Matthew Macauley

Publications

The Tiger Vol. 106 Issue 2 2012-01-27, Clemson University

Tiger Newspapers

4-H Science: Evaluating Across Sites To Critically Examine Training Of Adult Facilitators, Pamela Larson Nippolt

Journal of Youth Development

A Goal Setting Intervention Positively Impacts Adolescents’ Dietary Behaviors And Physical Activity Self-Efficacy, Mical Kay Shilts, Marilyn S. Townsend

Journal of Youth Development

Common Data Set 2011-2012, Clemson University

Common Data Sets

The Tiger Special Issue Spring 2012, Clemson University

Tiger Newspapers

Loft: The Observatory For X-Ray Timing, M. Feroci, J. W. Den Herder, E. Bozzo, D. Barret, S. Brandt, M. Hernanz, M. Van Der Klis, M. Pohl, A. Santangelo, L Stella, A Watts, J Wilms, S Zane

Publications

Measuring The Stellar Accretion Rates Of Herbig Ae/Be Stars, Brian Donehew, Sean D. Brittain

Publications

Manufacturing Process Modeling And Application To Intelligent Control, M. Laine Mears, Parakshit Mehta, Mathew Kuttolamadom, Carlos Montes, Joshua Jones, Wesley Salandro, Drew Werner

Publications

Wycinanki: Production Of A Non-Photorealistic Rendered Short Film, Irena Rindos

All Theses

Extending Origami Technique To Fold Forming Of Sheet Metal Products, Ala Qattawi

All Dissertations

Developing Hybrid Approaches To Predict Pka Values Of Ionizable Groups, Shawn Witham, Kemper Talley, Lin Wang, Zhe Zhang, Daquan Gao, Wei Yang, Emil Alexov

Publications

Progress In The Prediction Of Pka Values In Proteins, Emil Alexov, Ernest L. Mehler, Nathan Baker, Antonio Baptista, Yong Huang, Francesca Milletti, Jens Erik Nielsen, Damien Farrell, Tommy Carstensen, Mats H.M. Olsson, Jana K. Shen, Jim Warwicker, Sarah Williams, J Michael Word

Publications

Lithium In The Upper Centaurus Lupus And Lower Centaurus Crux Subgroups Of Scorpius-Centaurus, Eric J. Bubar, Marc Schaeuble, Jeremy R. King, Eric E. Mamajek, John R. Stauffer

Publications

Clemson Commencement Program, December 2011, Clemson University

Clemson Commencement Programs

An Investigation Of The Application Of Phase Change Materials In Practical Thermal Management Systems, David Ewing

All Dissertations

An Examination Of Variables Which Influence High School Students To Enroll In An Undergraduate Engineering Or Physical Science Major, Christopher Porter

All Dissertations

A Formal Representation Of Mechanical Functions To Support Physics-Based Computational Reasoning In Early Mechanical Design, Chiradeep Sen

All Dissertations

Computational Approaches To Understand Phenotypic Structure And Constitutive Mechanics Relationships Of Single Cells, Scott Wood

All Dissertations

Fluid Mud Underflows In Coastal Dredge Disposal, Mijanur Chowdhury

All Dissertations

Bases And Applications Of Riemann-Roch Spaces Of Function Fields With Many Rational Places, Justin Peachey

All Dissertations

Mechanical And Modular Verification Condition Generation For Object-Based Software, Heather Harton

All Dissertations

Modification And Characterization Of Fluorescent Conjugated Polymer Nanoparticles For Single Molecule Detection, Yueli Zheng

All Dissertations