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The Functional Implications Of Anuran Metamorphosis For Survival, Locomotor Performance, And Limb Bone Mechanical Properties, Chase Kinsey

All Dissertations

Many organisms must contend with navigating their environments from birth. An organism could be classified as – and is often studied – in the context of locomotion through a single habitat type. However, many organisms must contend with a wide variety of environmental obstacles and substrates. What’s more, a large group of animals, Lissamphibia, do so while undergoing drastic transformation of their morphology and locomotor appendages. This transformation, term metamorphosis, typically coincides with a movement from water as a tadpole, to land as a frog or salamander. Many studies have associated this transitionary period with decreased locomotor performance and worse …

Evaluation Of Bone And Muscle Quality In Laying Hens Using Quantitative, Radiographic, Computed Tomographic, Biomechanical, And Tissue Level Measures, Cerano Harrison

All Dissertations

Bone quality is an important measure of welfare in laying hens for researchers, veterinarians, and commercial producers who bear the responsibility of providing them with care. Breeding practices that have resulted in high egg productivity of laying hen strains have resulted in an increased susceptibility to developing osteoporosis. Osteoporosis, a decrease in mineralized bone, is accompanied by increased bone fragility that can lead to potentially painful bone fractures that can inhibit some aspects of the birds natural living, respiration and flight being two examples. Current methods of examining laying hen bone quality involve the implementation of diagnostic imaging and biomechanical …

Variability In Anesthesia And Its Implications For Improving Patient Safety, Joshua Michael Biro

All Dissertations

Improving patient safety in anesthesia has proven to be an arduous and challenging task. Despite the many strategies and interventions to improve patient safety that have been employed, patient harm in anesthesia remains a problem. The struggle to reduce patient harm in anesthesia is both attributable to and representative of the complexity of the anesthesia system. In navigating this complex system, anesthesia providers have different approaches to how they accomplish their work, which results in variability in anesthesia practice. This variability provides an immense challenge to designing and implementing efforts to improve patient safety, as rigid interventions are often met …

Protein A And Multimodal Anion-Exchange Membrane Adsorbers For Downstream Purification Of Therapeutic Biomolecules, Joshua Osuofa

All Dissertations

This dissertation explores development and characterization of membrane chromatography tools for downstream purification of therapeutic biomolecules. Convective technologies, particularly membrane chromatography, are emerging in the field of bioseparations as an alternative to resin chromatography due to their improved throughput capability. On the forefront of emerging membrane technologies are multimodal and Protein A membrane adsorbers. The overarching theme of this dissertation research was to investigate advances in these membrane chromatography tools. The primary objective was to develop and characterize novel Protein A membrane adsorbers. A secondary objective was to characterize newly commercialized Protein A and multimodal anion exchange membrane adsorbers.

Two …

Biology And Herbicide Resistance Characteristics Of Various Annual Bluegrass (Poa Annua L.) Biotypes From Across The United States, Jacob William Taylor

All Dissertations

Annual bluegrass (Poa annua L.) is one of the most problematic winter annual weeds in managed turfgrass systems, having rapidly adapted to different climates and management practices. Characteristics such as prolific seedhead production, clumped bunch-type growth habit, and lack of stress tolerance negatively impact turfgrass quality. Achieving adequate control can be difficult because annual bluegrass exhibits high levels of genetic diversity, the ability to germinate year-round, and has a high tendency for evolving herbicide resistance, currently resistant to at least nine different herbicide sites of action. Current management programs rely heavily on herbicides for control; however, frequent use without implementing …

Effect Of Authentic Kefir And Nigella Sativa On Broilers Challenged By Coccidia And Clostridium Perfringens, Julian E. Nixon

All Dissertations

Black seed oil concentrations of 0%, 0.1%, 1% and 5% were added to milk inoculated with kefir grains and incubated at 25°C for 22 h. The pH and microbial count indicated 1% black seed oil caused low inhibition (P > 0.05) of fermentation, but 5% black seed oil caused significant inhibition of the kefir microorganisms (P < 0.05).

Cobb 500 male chicks (n = 256) were distributed in a randomized block design and received one of four treatments: CTRL1 (Non-medicated, no kefir, no Clostridium perfringens), CTRL2 (Non-medicated, no kefir, C. perfringens inoculated), CTRL3 (BMD medicated, no kefir, C. perfringens inoculated), KTRT (Non-medicated, …

Unruly Periods: Reproductive Futurities And The Rhetorics Of Menstruation, Hannah Taylor

All Dissertations

“Unruly Periods: Reproductive Temporalities and the Rhetorics of Menstruations” argues that dominant rhetorics of shame and regulation around menstruation work to maintain strict reproductive temporalities that uphold heteropatriarchal norms. Specifically, I draw upon scholarship in queer studies and disability rhetorics to assert that sexual health texts (such as puberty books), menstrual care products (pads and tampons), and technologies of menstruation (period-tracking apps) function as a form of chronobiolitics—a teleological force that seeks to reinforce bodily normalcy. In doing so, these rhetorics of menstruation deny or elide the embodied experiences of diverse, queer, and disabled menstruators, limiting reproductive possibilities. Reproductive justice …

Coming Home: Challenges Of Reintegration For Returned Migrant Women In Northern Albania, Marsida Tafilica

All Dissertations

Return migration is the movement of people from host countries to their country of origin after spending a period of time abroad. The aim of this doctoral research is two-folded: Firstly, it aims to explore migration and return migration experiences of Albanian women in order to understand the difficulties experienced during and after migration and how they handled obstacles. Secondly, it analyzes how women migrants perceive successful reintegration.

Drawing on qualitative in-depth interviews of 19 Albanian women who returned to the city of Shkodra, the research seeks to answer the following questions: (1) Upon return, what are the perceptions of …

Improving Lignin Recovery From Paper Mill And Biorefinery Waste Streams Via Liquid-Phase Splitting, Carter Fitzgerald

All Dissertations

Lignin is an abundant biopolymer with significant promise due to its aromaticity. It has been targeted as a replacement for a number of petroleum-based products including adhesives, coatings, polyurethane foams, activated carbon, and carbon fibers. However, commercially available bulk lignins are too polydisperse, and contain too many residual metals from the pulping process that are detrimental to the properties of the final product.

The Sequential Liquid-lignin Recovery and Purification (SLRP) process was developed by Michael Lake and John Blackburn, in collaboration with Clemson, with the intention of creating a continuous method for recovering lignin from paper-mill black liquors. Thies and …

Mirna Regulation Of Skeletal Muscle Hypertrophy, Maslyn Greene

All Dissertations

Muscle tissue is vital to animal survival and economically essential to livestock producers. Reduced muscle growth can occur from various reasons, including genetics, nutrition, and the pre and postnatal environment. Understanding the mechanisms behind muscle growth can aid in developing strategies to increase muscle mass. Several methods to increase muscle mass in livestock animals are currently being pursued, including nutrition, hormonal therapy, and genetic selection. One newly developing avenue is using miRNA technologies to change the expression of protein-coding genes. miRNA are a type of RNA that regulate over half of protein-coding gene expression. Here we evaluate muscle characteristics such …

Investigating The Potential Of A Cell-Based Gene Editing Therapy For Inherited Metabolic Liver Disease, Ilayda Ates

All Dissertations

Inherited metabolic diseases (IMDs) affecting the liver are relatively rare but collectively have a prevalence of 1 in 800 live births. These diseases result from autosomal recessive single-gene mutations, leading to organ dysfunction and potentially fatal consequences if left untreated. One potential therapeutic strategy for IMDs of the liver involves using CRISPR-Cas9-induced loss of function mutations. However, translating this approach into the clinic is limited by the need for safe and effective CRISPR delivery methods. Adeno-associated viral vectors (AAVs), commonly used for CRISPR delivery, are associated with significant safety and efficacy concerns, including risks for immunogenicity, off-target mutagenesis, and genotoxicity …

Motion Synthesis And Control For Autonomous Agents Using Generative Models And Reinforcement Learning, Pei Xu

All Dissertations

Imitating and predicting human motions have wide applications in both graphics and robotics, from developing realistic models of human movement and behavior in immersive virtual worlds and games to improving autonomous navigation for service agents deployed in the real world. Traditional approaches for motion imitation and prediction typically rely on pre-defined rules to model agent behaviors or use reinforcement learning with manually designed reward functions. Despite impressive results, such approaches cannot effectively capture the diversity of motor behaviors and the decision making capabilities of human beings. Furthermore, manually designing a model or reward function to explicitly describe human motion characteristics …

Extensional Flows Of Polymer Solutions In Planar Microchannels, Mahmud Kamal Raihan

All Dissertations

Non-Newtonian fluids such as polymer solutions often flow under microscale extensional conditions in many natural and engineering flow fields such as in microfluidic chips, porous rocks, biological membranes and filters, printheads in additive manufacturing, etc. The changing cross sectional areas of the internal flow passages therein exert additional extension on the flow along with the shearing. Numerous studies have been dedicated to understanding the extensional flows of polymer solutions over the years. However, most of these studies only focused on flexible polymers exhibiting elasticity in their macroscopic rheology, whereas rigid polymers that portray shear-thinning but often elude elasticity in the …

Atom Economical Reactions Of Terpenoids And Post-Consumer Plastics With Sulfur, Charini Maladeniya

All Dissertations

The production of Ordinary Portland Cement (OPC) and its uses have a complicated environmental impact, which is influenced by infrastructure development and building operations as well as CO₂ emissions, which account for 7% of all worldwide CO₂ emissions. Due to the increasing population, production is still ongoing. The search for cement and construction materials produced with zero to low CO₂ emissions is therefore continuous. Finding recyclable, CO₂ gas-free biocomposites with high sulfur content that can rival the mechanical properties of popular building supplies like Portland cement is the primary objective of the research discussed in this …

Storytelling In Motion: Rhetorical Approaches To Autoethnography, Critical Pedagogy, And African Filmmaking, Sethunya Mokoko

All Dissertations

This dissertation exposes the marginalization in the education systems of my country Lesotho, South Africa, an injustice that still survives long after the plague of Apartheid. Drawing on the values in African epistemologies of storytelling, I describe and illustrate their principles, then show how storytelling can transform composition pedagogy and thus help eradicate the residue of colonization. The methodology draws from auto-ethnography, narrative, spoken word, traditional oral wisdom, and African filmmaking as counter-story and resistance to the ideologies plaguing the minds of colonized South Africans. The goal is to celebrate oral traditions while improving reading comprehension and writing. With an …

In Vitro And In Vivo Diabetic Models For Assessment Of Tissue Engineered Vascular Grafts, Juan Carlos Carrillo Garcia

All Dissertations

Diabetes has become one of the leading causes of lower-limb loss worldwide. Every 30 seconds, a person loses a limb due to diabetic-related vascular complications. About one-third of patients needing lower-limb bypass surgery have debilitated autologous vessels unsuitable for use, and no other good long-term options are available. These detrimental effects on the vasculature are caused mainly by the hyperglycemic and hyperlipidemic conditions derived from diabetes. Under these conditions, an increase in advanced glycation end products (AGEs) and reactive oxygen species leads to irreversible crosslinks of extracellular matrix proteins, accelerating vascular pathology through vascular stiffening, endothelial dysfunction, inflammation, atherosclerosis, fibrosis, …

Isolation Of Bovine Milk-Derived Exosomes Via A Polyester Capillary- Channeled Polymer (C-Cp) Fiber Stationary Phase, Jerisa Pimentel, Carolina Mata, R. Kenneth Marcus

Chemistry Summer Research Program

No abstract provided.

Chlorophyll A Predictions In A Piedmont Lake In Upstate South Carolina Using Machine-Learning Approaches, Ibrahim O. Busari, Debabrata Sahoo, Raghavendra Jana, Charles Privette

Journal of South Carolina Water Resources

Freshwater systems are often breeding grounds for harmful algal blooms (HABs), although they are more dominant in ponds and lakes due to the prevailing conditions in those bodies of water. Therefore, the monitoring, modeling, and management of HABs requires knowledge of the complex interrelationship between factors that influence HABs and their detrimental effect on the ecosystem. High concentrations of chlorophyll a are often used to measure algal blooms in bodies of water. Generally, water samples are collected from the field and the concentration of chlorophyll a is measured in a laboratory and compared to water quality standards in order to …

Full Issue - Volume 9, Issue 1

Journal of South Carolina Water Resources

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Workingwomen-Volcano-Slag And Virginia Woolf’S Queer Inhumanisms, Chen Rupeng

Virginia Woolf: Selected Papers

No abstract provided.

Why Look At Fish? Virginia Woolf’S Piscine Aesthetics, Marlene Dirschauer

Virginia Woolf: Selected Papers

No abstract provided.

Contemplating Reality: Unfolding The Ethics Of Attention In Mrs. Dalloway And To The Lighthouse, Krisztina Kitti Tóth

Virginia Woolf: Selected Papers

No abstract provided.

Daoist Attunement To The Nonhuman: The Mysticism Of Mundane Objects In Virginia Woolf’S To The Lighthouse, Xueying Zhou

Virginia Woolf: Selected Papers

No abstract provided.

Virginia Woolf & Ecologies: Selected Papers From The 32nd Annual International Conference On Virginia Woolf, Full Issue, Shilo Mcgiff, Laci Mattison

Virginia Woolf: Selected Papers

No abstract provided.

Ecologies Of Illness In The Voyage Out And Flush, Caylee Weintraub

Virginia Woolf: Selected Papers

No abstract provided.

Seaweeding With Virginia Woolf, Jeanne Dubino

Virginia Woolf: Selected Papers

No abstract provided.

Nonhuman Beings, Existential Anxiety, And Schopenhauer In Virginia Woolf’S Work, Yoshiki Tajiri

Virginia Woolf: Selected Papers

No abstract provided.

Ecologies Of Madness: Reading Virginia Woolf’S Life And Work Through Deleuze And Guattari, Kimberly Jackson

Virginia Woolf: Selected Papers

No abstract provided.

Speculating On Obscurity: Virginia Woolf’S Fictionalization Of Real Lives As An Alternative To Hegemonic Tellings Of History, Mariana Muniz Pivanti

Virginia Woolf: Selected Papers

No abstract provided.

Virginia Woolf And Deep Ecology, Kathryn Van Wert

Virginia Woolf: Selected Papers

No abstract provided.