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Articles 2731 - 2760 of 5973
Full-Text Articles in Entire DC Network
The Role Of Car And Pxr In Toxicant Sensitivity, Linda Mota
The Role Of Car And Pxr In Toxicant Sensitivity, Linda Mota
All Dissertations
The Constitutive Androstane Receptor (CAR) and the Pregnane X Receptor (PXR) are nuclear receptors of significant importance in the regulation of enzymes that metabolize, detoxify and eliminate compounds from the body. In this study we assessed the protective role of CAR and PXR in the basal and inducible regulation of Cytrochrome P450s (CYPs), and the potential of CAR and PXR to help protect individuals from the organophosphate, parathion and the plasticizer, nonylphenol, putatively due to improved metabolism and elimination. Knockout models of these receptors were used to model susceptible populations such as children that are known to have lower CAR …
An Exogenous Approach To Circumventing Demolition By Neglect: The Impact Of Agricultural Preservation On Historic Colonial Towns, Galen Newman
All Dissertations
The effects of city decentralization and counter-urbanization of the American landscape have resulted in simultaneous negative impacts on both historic structures and agricultural landscapes. Rapid conversion of farmland has helped to facilitate the relocation of both populations and commercial activities in communities across the United States, leaving inner cities replete with functionless, unused, and unmaintained heritage structures. As civic core areas have become shells of their former selves, many once-vital structures have been removed while others have been abandoned and left to decay--a process known as demolition by neglect. While historic preservation efforts have attempted to salvage these historic structures, …
An Examination Of Heritage Resource Internship Experiences And Land Management Agency's Role In Inspiring Emerging Leaders, Carin Vadala
An Examination Of Heritage Resource Internship Experiences And Land Management Agency's Role In Inspiring Emerging Leaders, Carin Vadala
All Dissertations
To address the shortage of people seeking to fill employment vacancies, the land management agencies are using the Student Conservation Association (SCA) and internships as a means of recruiting the next generation of leaders. Yet little research has been conducted on internships in cultural and natural heritage resource parks. This study used a two-phase linear exploratory method to investigate the experiences of cultural and natural heritage resource interns. Additionally, the study sought to determine if and how internships shape vocational, recreational, social and personal identities concerning parks and protected areas. Using significant life experiences, environmental socialization and emerging adulthood theories, …
Chemical Modification And Biological Activity Exploration Of The Natural Product-Gossypol, Juanjuan Yin
Chemical Modification And Biological Activity Exploration Of The Natural Product-Gossypol, Juanjuan Yin
All Dissertations
Gossypol is a naturally occurring, highly colored yellow pigment indigenous to the small intercellular pigment glands of the cotton plant genus Gossypium, which is proposed to be part of plant's defense system. Gossypol is characterized by wide contraceptive, antiviral, anticancer and antifungal properties. However, the relatively high toxicity of gossypol precludes its application in medical therapy. For this reason the syntheses and tests of gossypol derivatives, have been tried to enable their application as drugs. In our study, gossypol based methylation, glycosylation and nanoconjugate reactions were explored. The gossypol derivatives were all fully characterized by NMR, MS, FT-IR, UV spectrometry, …
Simulation And Mathematical Modeling To Support Community-Wide Evacuation Decisions For Multiple Population Groups, Jun Duanmu
All Dissertations
Evacuating a large population from an at-risk area has been the subject of extensive research over the past few decades. In order to measure trip completion and total evacuation times accurately, most researchers have implemented some combination of simulation and optimization methods to provide vehicular flow and congestion data. While the general at-risk population comprises the majority of travelers on the road network, there are often specific groups to consider when assessing the ability to evacuate an entire population. In particular, healthcare facilities (e.g., hospitals) may require evacuation, and the trip times may become an important health issue for patients …
Development Of Tissue Engineered Test Systems To Study Mammary Cell Interactions In Vitro, Cheryl Cass
Development Of Tissue Engineered Test Systems To Study Mammary Cell Interactions In Vitro, Cheryl Cass
All Dissertations
The work described in this dissertation was conducted in the interdisciplinary research environment of the Clemson University Institute for Biological Interfaces of Engineering. A note at the beginning of each chapter acknowledges, as relevant, collaborating doctoral students and reminds the reader where work from each chapter has been presented or published. The overall goal of this work was to develop tissue engineered test system methodologies to allow the study of mammary cell interactions in vitro. The background, as described in Chapter 1, was published in part in Philosophical Transactions of the Royal Society A in 2010. The studies were designed …
Essays In Contemporary Tax Law Changes, Arpita Biswas
Essays In Contemporary Tax Law Changes, Arpita Biswas
All Dissertations
In the first essay, I provide estimates of price and income elasticities of charitable contributions which reveal substantial differences in giving patterns across different income groups. The paper develops an intertemporal model of giving which predicts that lowering current income taxes induces substitution away from current giving towards giving in future periods. Cragg's Generalized Tobit model applied to Consumer Expenditure data from 1997-2006 provides estimates of income and price elasticities conditioned upon contribution, which range between 0.17 to 0.81 and −0.50 to −1.16 respectively. Empirical analysis shows substantial evidence of intertemporal substitution, implying that if the difference between future and …
Simulating And Assessing The Southern Pine Beetle Spot Growth On Management Scenarios Using Gis-Based Model And 3-D Landscape Visualization, Chiao-Ying Chou
Simulating And Assessing The Southern Pine Beetle Spot Growth On Management Scenarios Using Gis-Based Model And 3-D Landscape Visualization, Chiao-Ying Chou
All Dissertations
Models for simulating southern pine beetle (SPB), Dendroctonus frontalis Zimm., population dynamics and infestation risk are quite well developed. However, most of them are not spatially explicit models. In this study, a GIS-based model, SPBSPOT, is developed for simulating SPB spot growth using ArcGIS software with ArcObject and Visual Basic for Application. SPBSPOT is built by five subroutines. Individual interfaces are developed for each of them to allow users the flexibility to specify stand situations and design management scenarios based on their individual needs. Although integrated pest management systems are currently adopted, SPB management is still challenging because of diverse …
Using Fees And Charges To Fund Government, 2010 July, Holley Hewitt Ulbrich
Using Fees And Charges To Fund Government, 2010 July, Holley Hewitt Ulbrich
Publications
No abstract provided.
Cell-Mediated Elastic Matrix Regeneration Toward Regression Of Abdominal Aortic Aneurysms, Carmen Gacchina
Cell-Mediated Elastic Matrix Regeneration Toward Regression Of Abdominal Aortic Aneurysms, Carmen Gacchina
All Dissertations
Abdominal aortic aneurysms (AAAs) are typically fusiform (symmetric) dilations of the aortic wall most commonly arising below the renal arteries. The progression is typically associated with an activated smooth muscle cell (SMC) phenotype, diminished density of mature medial elastic fibers, and an elevated presence of matrix-degrading enzymes (e.g., matrix-metalloproteases; MMPs), which may ultimately lead to vessel rupture. Currently, no surgical or non-surgical methods are available to regress AAAs via regeneration of new elastin matrices to regain normal vessel contour, particularly due to the inherently poor elastin synthesis by adult vascular cells and absence of methods to stimulate the same. Previously, …
Methods Of Isolating Specific Compounds From Supramammary Lymph Node Tissue, Steven E. Ellis, Thomas R. Scott
Methods Of Isolating Specific Compounds From Supramammary Lymph Node Tissue, Steven E. Ellis, Thomas R. Scott
Clemson Patents
Methods of forming proteinaceous products such as cell culture supplement capable of supporting the growth and culturing of cells, tissue, and organs, are generally disclosed. One method generally provides for the collection of the internal tissue of an animal, such as a bovine, and the processing of the internal tissue to degrade and/or lyse the tissue components. A cell culture supplement or other proteinaceous product can be prepared from the processed tissue. A proteinaceous product can include, for example, a complete protein profile of the tissue or only certain biological factors extracted from the tissue. Collected internal tissue can be …
Clemson Commencement Program, May 2010, Clemson University
Clemson Commencement Program, May 2010, Clemson University
Clemson Commencement Programs
No abstract provided.
Analysis Of Egg-Lay Dates Of Bald Eagles As A Potential Indicator Of Global Climate Change, Jennifer Garrison
Analysis Of Egg-Lay Dates Of Bald Eagles As A Potential Indicator Of Global Climate Change, Jennifer Garrison
All Theses
The effects of climate change on many wildlife species is a new area of research. Long&ndashterm data sets on raptor populations may hold the key to documenting these impacts from local to ecosystem scales. The Michigan bald eagle (Haliaeetus leucocephalus) population has been monitored continuously since 1961, and virtually all reproductive outcomes are known since 1963. The bald eagle population at Voyageurs National Park, Minnesota has been monitored continuously since 1973. Though these data sets are extensive, little is known about the effects of climate change on egg laying dates in sea eagles (Haliaeetus spp). Understanding these effects could ultimately …
Growth And Hydrogen Production From Carbohydrates And Switchgrass By Thermotoga Neapolitana, Divya Dharshini Chandrasekaran
Growth And Hydrogen Production From Carbohydrates And Switchgrass By Thermotoga Neapolitana, Divya Dharshini Chandrasekaran
All Theses
Thermotoga neapolitana is an anaerobic thermophilic marine bacterium that has been reported to degrade cellulose. This hyperthermophilic bacterium grows at 77¡C and could be used in large scale applications because of its ability to withstand extreme conditions. The aim of this study was to analyze the growth and production of hydrogen by T. neapolitana when grown on various carbon sources including the bioenergy crop switchgrass. Switchgrass was provided by the Clemson University Pee Dee Research and Education Center and was milled to about 4mm in size. Switchgrass was then added to an anaerobic medium and inoculated with T. neapolitana . …
Establishment And Management Practices Of Two New Warm-Season Turfgrasses In The Southern Transition Zone, John Stiglbauer
Establishment And Management Practices Of Two New Warm-Season Turfgrasses In The Southern Transition Zone, John Stiglbauer
All Theses
Seashore paspalum (Paspalum vaginatum O. Swartz) is a turfgrass that has become increasingly popular in southern coastal regions of the US because of its ability to tolerate salt stress. Another reason that this turfgrass is increasing in popularity is its aesthetically appealing striping ability. Seashore paspalum could also be beneficial in areas where potable water cannot be used for irrigation. Information on this turfgrass is limited in literature, particularly on the topics of establishment, scalping, and growing this turfgrass on inland sites in the transition zone. A field experiment was conducted in Clemson, SC from May 2007 and 2008 to …
Why Jerusalem? Why Then?, Erin Larson
Why Jerusalem? Why Then?, Erin Larson
All Theses
One of the fascinating aspects of this research is how what individuals believe to be true leads to collective action as a society. Research for this paper will show the evolution of Christian theology from the early Christian rejection of the physical world to the medieval reliance on physical people, places and objects as a connection to heaven. This paper will also track the creation of penitential warfare as a way of entering heaven. This paper will prove that Jerusalem was important to medieval Europeans for three reasons: saving the city from the Muslims was an act of penance, the …
A Christmas Tree And Other Stories, Jillian Lang
A Christmas Tree And Other Stories, Jillian Lang
All Theses
The stories presented in this thesis are written mainly in the vein of literary minimalism and post-Modernism. The stories focus on a variety of themes, as related to human emotions and reactions. The thesis begins with A Christmas Tree, which focuses on the opinions and reactions of a mentally-handicapped man as he struggles with his desires to be an average, contributing member of society. The second story in the collection, The Little Red Schoolhouse, focuses on sexuality and how pride and dishonesty can ruin an otherwise successful relationship.A Learned Helplessness and Supper Club, stories three and four in the collection, …
The Scarf Club, Mari Ramler
The Scarf Club, Mari Ramler
All Theses
A novel comprises this creative thesis, which has been submitted in partial fulfillment for the degree of Master of Arts in English literature. This manuscript is the story of Lucy Merdock and how two major losses during her senior year of high school change the way she sees herself.
Biodegradable Polymer Blends And Composites From Proteins Produced By Animal Co-Product Industry, Bernice Nzioki
Biodegradable Polymer Blends And Composites From Proteins Produced By Animal Co-Product Industry, Bernice Nzioki
All Theses
ABSTRACT
Development of new green materials from by-products of animal rendering industries would provide a substantial economic return to animal rendering processors. Meat and bone meal (MBM), one of the products of the rendering industry, has potential for numerous bio-based applications. This research focuses on fabrication of plastics blends made of MBM (Meat and bone meal) and UHMWPE (ultra high molecular weight polyethylene). We investigated thermal, morphological, water absorption and mechanical properties of the plastics. The plastics were compression molded and their properties were examined.
DSC thermographs of the blends indicated that the thermal properties of UHMWPE did not change …
Making Rhetorical Scents: An Olfactory Grammar Of Motives Based On Kenneth Burke's Pentad, Janet Miller
Making Rhetorical Scents: An Olfactory Grammar Of Motives Based On Kenneth Burke's Pentad, Janet Miller
All Theses
Scent is inherently persuasive, but the language of scent is largely missing from rhetoric's vocabulary. This is because language cannot express the 'truth' of an odor. Identification of odor as substance is dependent on consubstantiality between the author and reader. We instead describe smells using metaphorical language, or by invoking episodic memories and emotional reactions. In this way, scent is dramatistic. In order to consider the possibility of a grammar of scent beyond metaphor, the author develops an olfactory pentad (Sniff, Context, Emanation, Odor Object, and Response) by applying the framework of Kenneth Burke's dramatistic pentad. In this way, scent …
The Effects Of Aerobic Exercise On Embryonic And Fetal Development In The Pregnant Mare, Jason Anton
The Effects Of Aerobic Exercise On Embryonic And Fetal Development In The Pregnant Mare, Jason Anton
All Theses
Horses are natural athletes and are commonly competed during early pregnancy. Because horses have singleton pregnancies and are conditioned to human interaction, they may prove to be a useful model in lending greater understanding of the numerous etiologies of intra-uterine growth restriction that is found in women and other mammals. Currently, there has been little research conducted to determine the effects that stress, in the form of aerobic exercise, has on early embryonic and fetal development in the horse. More research is needed to further understand the effects that stress has on early conceptus development in the mare.
The research …
Mult1e-Rgd Fusion Protein Drives Nk Cell-Mediated Anti-Tumor Response, Meg Steiner
Mult1e-Rgd Fusion Protein Drives Nk Cell-Mediated Anti-Tumor Response, Meg Steiner
All Theses
A growing body of evidence indicates that natural killer (NK) cells are paramount to the identification and elimination of cancerous and pre-cancerous cells during normal immunosurveillance. In addition, NK cells provide a vital link between the innate and adaptive immune systems during an anti-tumoral response. In the present study, a novel fusion protein was designed from the extracellular portion of mouse UL16-binding protein-like transcript 1 (MULT1), a ligand for the activating NKG2D receptor on NK cells, and a short arginine-glycine-aspartic acid (RGD) -containing peptide, which binds the integrin αvβ3 of tumor-specific neovasculature. In vitro studies showed that the fusion protein …
Examining The Behavioral Intentions Of Older Adults As Virtual Tourists In The Context Of A Second Life Destination, Dorinda Christian
Examining The Behavioral Intentions Of Older Adults As Virtual Tourists In The Context Of A Second Life Destination, Dorinda Christian
All Dissertations
ABSTRACT
Tourism opportunities are being promoted heavily on the web, yet one of the largest and most lucrative markets, older adults are least likely to use the internet. In an effort to explore barriers to and potential acceptance of technology for tourism experiences, this study followed closely ten older adults through a learning process with technology. Qualitative methodology was used to explore in-depth the experience of these older adults being exposed to online virtual world technology for the first time and exploring the process by which technology acceptance takes place. The findings indicate that online virtual world such as Second …
The Accuracy Of Observers' Estimates Of The Effect Of Glare On Nighttime Vision: Do We Exaggerate The Disabling Effects Of Glare?, Stacy Balk
All Dissertations
Designing headlights involves balancing two conflicting goals: maximizing visibility for the driver and minimizing the disabling effects of glare for other drivers. Complaints of headlight glare have increased recently. This project explored the relationship between subjective (discomfort and expected visual problems) and objective (actual visual problems) consequences of glare. Two experiments - a lab-based psychophysical study and a field study - quantified the accuracy of observers' estimates of the effects of glare on their acuity. In both experiments, participants over-estimated the extent to which glare degraded their ability to see a small high contrast target. Observers' estimates of the disabling …
Immunomodulatory Properties Of Noni (Morinda Citrifolia), Madhukar Lohani
Immunomodulatory Properties Of Noni (Morinda Citrifolia), Madhukar Lohani
All Theses
Noni (Morinda citrifolia) is a popular medicinal plant of family Rubiaceae. Its fruit is rich in various phytochemicals and polysaccharides. Anecdotal evidence indicates that it was used to stimulate the immune system and, thus, to fight various infections. Limited in vitro studies also support the immunomodulatory role of Noni, however only one study utilized an animal model. The purpose of this study was to examine the immunomodulatory properties of Noni fruit the broiler chicken.
Different concentrations of dietary Noni were added to diets and fed to day-old broiler chickens for 3 to 6 weeks. Gut tissue and blood were sampled …
Responses Of Problematic Algae To Algaecide Exposures, West Bishop
Responses Of Problematic Algae To Algaecide Exposures, West Bishop
All Theses
Excessive growths of algae can cause significant disruption of critical water resource usages including: drinking, irrigation, recreation as well as be aesthetically displeasing. Water resource managers are often compelled to take action to mitigate these nuisance algal infestations. Algaecides can be efficient and effective management options to rapidly suppress algal blooms and restore water usages. However, laboratory and field data are required to accurately predict responses to an application as well as potential risks to non-target organisms. Laboratory experiments were used to measure the responses of problematic algae to algaecide exposures and evaluate the margin of safety to sensitive, non-target …
Image-Based Modeling Techniques For Artistic Rendering, Bynum Murray Iii
Image-Based Modeling Techniques For Artistic Rendering, Bynum Murray Iii
All Theses
This thesis presents various techniques for recreating and enhancing two-dimensional paintings and images in three-dimensional ways. The techniques include camera projection modeling, digital relief sculpture, and digital impasto. We also explore current problems of replicating and enhancing natural media and describe various solutions, along with their relative strengths and weaknesses. The importance of artistic skill in the implementation of these techniques is covered, along with implementation within the current industry applications Autodesk Maya, Adobe Photoshop, Corel Painter, and Pixologic Zbrush. The result is a set of methods for the digital artist to create effects that would not otherwise be possible.
A Discounted Cash Flow Method Of Valuation For Single Trees And Urban Forests, Kristin Heffelfinger
A Discounted Cash Flow Method Of Valuation For Single Trees And Urban Forests, Kristin Heffelfinger
All Theses
Urban foresters need a consistent method for valuing single trees with specific non-timber values. There are several accepted methods to accomplish this; comparison of results across the methods ensures consistency. Discounted cash flow analysis (DCF) is one of these methods, but many appraisers or others valuing urban tree are reluctant to use it because it requires complex calculations and assumptions. However, DCF has the advantage of accounting for the time value of money and certain intangible benefits presented by urban trees. Current models are adapted to specific locations and species; a general method for urban tree valuation has not been …