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Upic Magazine, Issue 9, Center For Career And Professional Development

UPIC Magazine

Every semester, undergraduate students from every major and staff from every part of Clemson University join together through UPIC internships. These paid internships grant students real, on the job experience in professional fields and offer staff a chance to mentor some of Clemson’s most brilliant students.

To find out more about the UPIC Program, visit career.clemson.edu/internship_programs

UPIC is part of Clemson’s Center for Career and Professional Development

Coating Orthopedic Implants With An Epoxy Based Ph Sensitive Layer To Image Ph Changes On Implant Surface Through Tissue Using X-Ray Excited Luminescence Chemical Imaging, Unaiza Uzair, Chloe Johnson, Donald Benza, Shayesteh Beladi

Graduate Research and Discovery Symposium (GRADS)

Implant-associated infection is a leading cause of fixation failures and is often challenging to detect due to lack of symptoms and specific tests to detect localized infection. Low pH is believed to be associated with infection as bacteria and inflammatory responses cause a pH drop in the affected area. Previously we have developed a pH sensitive coating to detect these pH changes and thus indicate infection but it has been challenging to completely cover the implant surface using this coating. Herein we introduce a method to coat the entire orthopedic plate using an epoxy based coating. First step is to …

Toxicological Effects Of Tire Wear Particles On Mummichogs And Fathead Minnows, Stephanie B. Laplaca, Peter Van Den Hurk

Graduate Research and Discovery Symposium (GRADS)

Recent studies on the distribution of microplastics in the Charleston Harbor, SC, revealed that a large part of the microplastic particles that are found in the intertidal sediments are tire wear particles. These particles originate from the wear of tire treads on roadways, and wash into the estuary during rain events. The abundance of these particles has raised questions about potential toxicity to aquatic organisms that may ingest these particles. The synthetic rubber in car tires consist of a large variety of chemicals, which can vary between brands, but usually contains styrene-butadiene rubber, carbon black and zinc. To investigate the …

The Tiger Vol. 113 Issue 3 2019-03-11, Clemson University

Tiger Newspapers 2019

No abstract provided.

A Hybrid Experimental‐Computational Modeling Framework For Cardiovascular Device Testing, Ethan Kung, Masoud Farahmand, Akash Gupta

Publications

Significant advances in biomedical science often leverage powerful computational and experimental modeling platforms. We present a framework named physiology simulation coupled experiment (“PSCOPE”) that can capitalize on the strengths of both types of platforms in a single hybrid model. PSCOPE uses an iterative method to couple an in vitro mock circuit to a lumped-parameter numerical simulation of physiology, obtaining closed-loop feedback between the two. We first compared the results of Fontan graft obstruction scenarios modeled using both PSCOPE and an established multiscale computational fluid dynamics method; the normalized root-mean-square error values of important physiologic parameters were between 0.1% and 2.1%, …

The Tiger Vol. 113 Issue 18 2019-02-18, Clemson University

Tiger Newspapers 2019

No abstract provided.

Comprehensive Annual Financial Report 2018, Clemson University Controller's Office

Annual Comprehensive Financial Report

No abstract provided.

Supplemental Schedules For The Year Ended June 30, 2019, Clemson University Controller's Office

Supplemental Schedules

No abstract provided.

Modeling And Measuring Students' Computational Thinking Practices In Science, Golnaz Arastoopour Irgens, Sugat Dabolkar, Connor Bain, Philip Woods, Kevin Hall, Hillary Swanson, Michael Horn, Uri Wilensky

Publications

In recent decades, computational tools and methods have become pervasive in mathematical and scientific fields (National Research Council, 2010a). Tools such as mathematical and statistical models have expanded the range of phenomena that are explored and have become necessary for analyzing increasingly large data sets across disciplines (National Academy of Sciences, National Academy of Engineering, & Institute of Medicine, 2007). With these advances, entirely new fields such as computational statistics, neuroinformatics, and chemometrics have emerged. The varied applied uses of computational tools across these fields have shown that future scientists will not only need to know how to program, but …

Shattering The Crystal Goblet: Seeking A Pedagogy Of Visuality In Post - Typographic Expository Texts, David Reinking

Publications

This article synthesizes diverse theoretical perspectives toward developing a pedagogy that addresses the visuality of digital texts. To frame those perspectives and their implications, I use a well - known analogy that Beatrice Warde introduced to typographers in the 1930s: drinking wine from a golden cup or a crystal goblet. I briefly review the theory and research related to visual aspects of texts, generating pedagogical perspectives from several prominent theories and perspectives. I then discuss, illustrated with a few examples, how these pedagogical perspectives might be instantiated in curriculum and instruction and the issues and challenges of doing so. I …

Heuristics For Communicating Science, Risk, And Crisis, Katherine E. Rowan, Andrew S. Pyle

Publications

Scientific information about physical hazards is important and very easy to miscommunicate. Because science uses complex wording and sophisticated reasoning, many assume that sharing science with lay stakeholders is solely a matter of substituting simple words and sentences for unfamiliar terms and complex syntax. An additional frequent assumption is that ‘giving information’ or ‘educating’ are the only important goals when communicating with stakeholders about health and the environment. Indeed, one study shows that, among scientists who share science online with lay stakeholders, their principal goals when communicating with lay audiences are to ‘educate’ or ‘defend science’. Although these goals are …

Phylogenetic Origins For Severe Acetaminophen Toxicity In Snake Species Compared To Other Vertebrate Taxa, Peter Van Den Hurk, Harold M.I. Kerkkamp

Publications

While it has been known for a while that some snake species are extremely sensitive to acetaminophen, the underlying mechanism for this toxicity has not been reported. To investigate if essential detoxification enzymes are missing in snake species that are responsible for biotransformation of acetaminophen in other vertebrate species, livers were collected from a variety of snake species, together with samples from alligator, snapping turtle, cat, rat, and cattle. Subcellular fractions were analyzed for enzymatic activities of phenol-type sulfotransferase and UDP‑glucuronosyltransferase, total glutathione S‑transferase, and N‑acetyltransferase. The results showed that none of the snake species, together …

Sibling Sex, But Not Androgens, Shapes Phenotypes In Perinatal Common Marmosets (Callithrix Jacchus), Brett M. Frye, Lisa G. Rapaport, Michael W. Sears, Talia Melber, Suzette D. Tardif

Publications

When offspring share a womb, interactions among fetuses can impart lasting impressions on phenotypic outcomes. Such intrauterine interactions often are mediated by sex steroids (estrogens and androgens) produced by the developing fetuses. In many mammals, intrauterine interactions between brothers and sisters lead to masculinization of females, which can induce fitness consequences. Many litter-bearing primates, though, seem to escape androgen-mediated litter effects, begging why? Here, we investigated how the sex composition (i.e., same- or mixed-sex) of litters influences perinatal outcomes in the common marmoset monkey (Callithrix jacchus), using a combination of physiological, morphological, and behavioural assays. We hypothesized that …

Sibling Sex, But Not Androgens, Shapes Phenotypes In Perinatal Common Marmosets (Callithrix Jacchus), Brett M. Frye, Lisa G. Rapaport, Talia Melber, Michael W. Sears, Suzette D. Tardif

Publications

When offspring share a womb, interactions among fetuses can impart lasting impressions on phenotypic outcomes. Such intrauterine interactions often are mediated by sex steroids (estrogens and androgens) produced by the developing fetuses. In many mammals, intrauterine interactions between brothers and sisters lead to masculinization of females, which can induce fitness consequences. Many litter-bearing primates, though, seem to escape androgen-mediated litter effects, begging why? Here, we investigated how the sex composition (i.e., same- or mixed-sex) of litters influences perinatal outcomes in the common marmoset monkey (Callithrix jacchus), using a combination of physiological, morphological, and behavioural assays. We hypothesized that …

Key Habitat Features Facilitate The Presence Of Barred Owls In Developed Landscapes, Marion A. Clement, Kyle Barrett, Robert F. Baldwin

Publications

As urbanization continues to transform landscapes, it is imperative to find ways to conserve biodiversity within fragmented habitats. Forest interior dwelling birds are particularly vulnerable to development pressures because they require large tracts of forest to support their life cycles. Although Barred Owls (Strix varia) are frequently described as an obligate mature forest species, they have been found in urbanized landscapes. To determine if certain habitat characteristics, such as mature trees, facilitate the presence of Barred Owls in developed regions, we modeled Barred Owl occupancy probability along a development gradient in the Piedmont region of the southeastern United …

Sherwood Forest Book Club: Promoting Intrinsic Motivation For Life Long Learning, Megan Davis

ACA National Camp Research Forum Abstracts

No abstract provided.

College For Kids' 2018 Summer Camp: Improving Perceptions Of Science And Shaping Lifestyle Choices, Samuli M.O. Rauhalammi, Jamie C. Wolgast, Elissa F. Craig, Theresa M. Radke

ACA National Camp Research Forum Abstracts

No abstract provided.

Clemson Commencement Program,December 2018, Clemson University

Clemson Commencement Programs

No abstract provided.

Procedurally Generating Biologically Driven Bird And Non-Avian Dinosaur Feathers, Jessica Renee Baron

All Theses

A key element in computer-graphics research is representing the world around us, and immense inspiration may be found in nature. Algorithms and procedural models may be developed that can describe the three-dimensional shape of objects and how they interact with light. This thesis focuses particularly on bird and other dinosaur feathers and their structure. More specifically, it addresses the problem of procedurally generating biologically driven geometry for modeling feathers in computer graphics. As opposed to previously published methods for generated feather geometry, data is derived from a myriad of real-world specimens of feathers and used in creating graphical models of …

Exploring Purpose As A Resource For Promoting Youth Program Engagement, Anthony Burrow, Jennifer Agans, Nicolette Rainone

Journal of Youth Development

Recent evidence that reflecting on one’s purpose in life increases engagement with academic tasks inspires questions about whether purpose interventions might enhance learning engagement more broadly. This potential may be particularly fruitful for programs serving youth from a wide range of ages wherein sustaining engagement may be challenging. Here, we explored whether a brief purpose writing intervention would increase adolescents’ engagement in 4-H programs. Participants (N = 130) were randomly assigned to write about either their sense of purpose or a control topic prior to the first day of a program, and they reported their level of program engagement at …

Positive Interactions In Freshwater Systems, Samuel Clarence Silknetter

All Theses

The goals of this thesis are twofold, 1) to review the existing literature on positive interactions, and 2) to experimentally test the role of biotic context in a freshwater reproductive interaction. First, my co-authors and I have conducted a review of positive interactions in freshwaters to establish a direction for future research. By outlining case studies and causal mechanisms, we illustrate the diversity of positive interactions, and set the stage for a comprehensive look at the role of context in shaping interaction outcomes. Our research directive focuses on the value of both basic life history and experimental research, then using …

Tissue Engineering Platforms For Cardiac Pathology In Diabetes: In Vitro And In Vivo Studies, Laura Elizabeth Mccallum

All Dissertations

425 million people have diabetes worldwide, and by 2045 this number is estimated to increase to 629 million. The risk for cardiovascular diseases such as cardiomyopathy, hypertension, and atherosclerosis increase 5 and 2-fold for diabetic women and men respectively. Diabetic cardiomyopathy (DCMP) is a ventricular dysfunction that occurs in patients with diabetes independent of coronary artery disease, hypertension or valvular abnormalities. Hyperglycemia and dyslipidemia cause metabolic disturbances that adversely affect myocardial cells and extracellular matrix. These modifications alter overall myocardial structure and cardiac function, which can lead to heart failure.

As of now there is no specific marker for this …

Engineering Soft Tissue Replacements And The Development Of Novel Technologies To Heal These Wounds, Sarah Grace Dennis

All Dissertations

The primary focus of tissue engineering is to develop biological substitutes capable of restoring, maintaining, or improving native tissue function. This field advances an exciting array of solutions for organ repair and wound healing. In the United States alone over 6.5 million people are affected by chronic wounds every year, which account for over $25 billion of healthcare expenses. Vascularization and fast anastomosis with the host are essential in engineering cellular constructs that survive once implanted. In the last decade, there has been extensive investigation into fabrication techniques to create tissue replacements that are rapidly perfused post-implantation to address this …

Second Graders' Responses To And Application Of Word-Picture Relationships In Picturebooks: A Case Study, Koti Lee Hubbard

All Dissertations

Picturebooks are defined by the interaction of words and pictures to convey narrative (Bader, 1976; Kiefer, 1995; Sipe, 2011), referred to in this study as the word-picture relationship. This dissertation study extends on the work of others who investigated young children’s responses to picturebooks (e.g., Arizpe & Styles, 2016; Sipe, 2008a; Sipe & Bauer, 2001) and picturebook productions (e.g., Pantaleo 2017, 2018; Zapata, 2013) by placing word-picture relationships at the forefront of this study. This study employed an embedded, single-case study design to investigate second graders’ responses to word-picture relationships in contemporary realistic fiction and fantasy picturebooks during interactive read-alouds …

Models For Networks With Consumable Resources: Applications To Smart Cities, Hayato Montezuma Ushijima-Mwesigwa

All Dissertations

In this dissertation, we introduce different models for understanding and controlling the spreading dynamics of a network with a consumable resource. In particular, we consider a spreading process where a resource necessary for transit is partially consumed along the way while being refilled at special nodes on the network. Examples include fuel consumption of vehicles together with refueling stations, information loss during dissemination with error correcting nodes, consumption of ammunition of military troops while moving, and migration of wild animals in a network with a limited number of water-holes. We undertake this study from two different perspectives. First, we consider …

Association Of Drd2 Single Nucleotide Polymorphism And Fescue Toxicosis In Ruminants, Sarah Adams Wilbanks

All Dissertations

Fescue Toxicosis is a prevalent problem in the Southeastern, United States causing an estimated loss of one billion dollars per year to the livestock industry (Roberts & Andrae, 2010). There has been much research aimed at understanding the grass itself, the endophyte and the ergot alkaloids it produces, as well as its relationship and impacts on consuming animals. Many mitigation plans have been established and have been shown to control the amount of alkaloids subsequent animals are ingesting; however, research is at the tipping point of needing a genetic approach to fescue toxicosis. This research looked into the bovine genome …

On Some Environmental Applications Of Stochastic Processes, Liu Zhu

All Dissertations

This dissertation focuses on the study of some environmental applications of stochastic processes. In the first Chapter, we study an extreme value time series, where the extremes are derived using the block maxima/minima method. In extreme value analyses, the block maxima/minima are typically assumed to be statistically independent from block to block. However, extreme data arising from applications often present significant correlations. The main result of the chapter is to develop a simple and efficient method to estimate extreme model parameters and compute standard errors for them that account for correlation. More precisely, we develop a likelihood for sequences of …

Comparing The Therapeutic Efficacy Of Human Amniotic Membrane And Adipose-Derived Mesenchymal Stem Cells In Mitigation Of Osteoarthritis, Mackenzie Catherine Bowman

All Theses

Osteoarthritis (OA) is a leading cause of disability and pain to patients worldwide, and is characterized by abnormal subchondral bone remodeling, such as sclerosis and osteophyte formation, synovial tissue inflammation, and the destruction of articular cartilage, with limited capability for intrinsic repair. Currently, only palliative options are available to help treat the debilitating effects of the disease as there are no therapies authorized to halt or prevent the progression of OA. Due to the destructive nature of OA and a lack of current treatment options, there is an urgent need to develop novel therapies to mitigate the progression of OA. …

Evaluation Of Soybean Genotypes For Root Morphology, Hardpan Penetrability, Water Use Efficiency, And Yield, Harrison Gregory Fried

All Theses

Drought stress has been identified as the major environmental factor limiting soybean (Glycine max L. Merr.) yield in the United States and other parts of the world. Water use efficiency (WUE) that results in greater yield per unit of rainfall is an important parameter in determining crop yields in rain-fed production systems, and is often related with crop drought tolerance. Even though roots are major plant organs that perceive and respond to drought stress, their utility in improving soybean yield and WUE under different environmental and management conditions are largely unclear. The objectives of this research were to evaluate …

Do Open Spaces Provide Refuge For Anurans Within An Urban Matrix?, David Ruple Hutto

All Theses

Urbanization is among the largest threats to amphibian populations through habitat fragmentation, isolation, and outright destruction. Urban open spaces, such as parks and golf courses, have the potential to provide amphibians with suitable habitat within an urbanized matrix. During the spring and summer of 2018, I conducted dip net surveys and active call surveys to determine the presence and abundance of anurans at 51 wetland sites within the Piedmont ecoregion of South Carolina. Nearly one-third of these wetlands were located within urban open spaces, while the others were situated along a rural – urban gradient. Impervious surface and road density …