Digital Commons Network^™

Enhanced Transdermal Immunization Via Solid-In-Oil Nanodispersions Incorporating Dendritic Cell-Targeting Peptide, Md Samiul Islam, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie Wakabayashi, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto

Publications and Research

Transdermal immunization represents a promising needle-free alternative to conventional vaccination. However, efficient antigen delivery and robust immune activation remain major challenges. In this study, a solid-in-oil (S/O) nanodispersion system comprising a dendritic cell-targeting peptide (HR8), ovalbumin (OVA), and an adjuvant was developed for transdermal immunization. The HR8 peptide along with OVA was successfully incorporated into an S/O nanodispersion with an optimal hydrodynamic diameter of particles (< 200 nm) and exhibited stable physical properties for up to 90 days. In vitro and in vivo studies demonstrated enhanced antigen delivery with insignificant skin irritation in C57BL/6N mice. Moreover, in vivo transdermal immunization studies demonstrated that the addition of the HR8 peptide enhanced OVA-specific IgG responses (~1.5-fold). Notably, the HR8 peptide also promoted an approximately 2.5-fold increase in IgG2c levels, suggesting a shift toward a more T helper type 1-biased immune response, as reflected by an increased IgG2c/IgG1 ratio. Overall, these findings demonstrate that the incorporation of HR8 peptide into an S/O nanodispersion enables efficient transdermal antigen delivery and improved immunogenicity, highlighting its potential as a simple, non-invasive, and patient-friendly immunization strategy.

Social Psychology, Justin Storbeck, Justin Storbeck

Open Educational Resources

The document is a syllabus for a Social Psychology course. The course is designed as an introductory course to Social Psychology. The course consist of OER materials and designed to place no financial burden on the student. The major topics of social psychology will be covered using an OER textbook accompanied by lecture materials, assignments, videos, and learning objectives.

Math 141 Calculus I (Queens College), Anisha Clarke

Open Educational Resources

This syllabus provides the outline for a calculus one course using OpenStax Calculus Volume I and no graphing calculator.

Ai-Powered Knowledge Engines As Research Infrastructure For Systematic Knowledge Discovery, Gary Welz

Publications and Research

This paper proposes knowledge engines as a framework for understanding how intelligent systems — both human and artificial — systematically discover, integrate, and generate knowledge. We argue that history’s greatest scientific minds functioned as knowledge engines, processing information through iterative cycles of ingestion, analysis, synthesis, and communication, guided by curiosity and willingness to challenge established beliefs.

We propose a taxonomy of nine integrated capabilities — ingestion, digestion, analysis, calculation, comparison, connection, association, analogy, and multimodal communication — that any serious knowledge engine must combine systematically. The argument is deliberately integrative: achieving ambitious research goals requires orchestrating all nine capabilities within …

Climate Anxiety And Nurses’ Awareness, Motivation, And Behaviors In Addressing Climate-Related Health Risks, Sarah Kaplan

Theses and Dissertations

Background: Climate anxiety, the emotional distress associated with awareness of climate change and its consequences, is an emerging mental health concern that may influence how nurses perceive and respond to climate-related health risks. Climate change is largely driven by emissions of greenhouse gases which radiate and absorb heat. Human-caused climate change is leading to higher average global temperatures and increasing risk to health through poor air quality, changes in vector borne diseases, extreme weather events, and exacerbation and development of physical and mental illnesses. This study contributes to nursing science by examining climate anxiety and climate related health practices among …

Ecological Footprint Assessment, Santina Benincasa

Open Educational Resources

This handout guides students through a structured ecological footprint assessment using the online Footprint Calculator. By following a series of steps—selecting their location, entering detailed lifestyle information, and reviewing personalized results—students evaluate how many planets would be required if everyone lived with their same resource consumption patterns. The activity prompts learners to identify the largest contributors to their footprint, quantify their impact in global hectares, and explore scenario-based changes that could reduce their environmental demand. Through reflection, students consider how everyday human behaviors influence Earth’s productive capacity and resource availability. Overall, the exercise encourages critical thinking about sustainability and personal …

Notes From The Field - Conference Proceedings, Summer Fellows 2025, Center For Latin American, Caribbean, And Latino Studies (Clacls)

Center for Latin American, Caribbean, and Latino Studies

CLACLS presents proceedings papers from the third CLACLS Summer Fellows Showcase Conference, held on November 12, 2025.

The daylong event showcased the research endeavors of fourteen Summer Fellows, who offered succinct presentations on their projects funded by the CLACLS Summer fellowship. The included three panels: “Feminist and Queer Critical Perspectives”, “Language, Archive and Power”, “Social Movements and Political Imaginations.”

Signal And Substance: Why Methodological Sophistication Fails To Guarantee Inference, Aamir Rashid, Rizwana Rasheed

Publications and Research

Despite increasing analytical sophistication, empirical research in organization studies continues to suffer from fragile inference, uneven theoretical accumulation, and contested credibility. This paper seeks to explain why these problems persist by shifting attention from authors’ methodological choices to the evaluative dynamics of peer review. Adopting a conceptual and theory-analytic approach, the paper theorizes peer review as an inferential gatekeeping system. Drawing on research design, theory evaluation, and philosophy-of-science literatures, this study develops an analytical framework to examine how evaluative routines shape what constitutes empirical rigor during the review process. The analysis identifies five recurring reviewer blind spots: inferential scope inflation, …

Older Adults' Caregiving Expectations For The Future, Smita Ekka Dewan, Derek Tice-Brown, Janna C. Heyman, Henry J. Davis, Colette Phipps, Joanne Mcmahon, Laura Sutter, Ye Feng, Jacqueline Heyde

Publications and Research

The purpose of this cross-sectional study was to explore older adults' perception of caregiver stress and their anticipation of becoming a caregiver (N = 723). Bivariate analyses revealed that perceived caregiving stress was higher among older adults who were females, White/Non-Hispanics, with chronic health conditions, who had experienced prior physical and financial caregiving burdens and was lower among those with just a high school degree. Multivariate analyses revealed that perceived caregiving stress levels remained higher only for those with past experience with physical caregiving, those with chronic health conditions, older females and White/Non-Hispanic older adults. The overall model was …

The Double Attraction Paradox, Rem Jaen D. Krafft

Publications and Research

The Double Attraction Paradox is a podcast series that teaches adolescents how to navigate attraction through body language, limerence, and mirroring while understanding the psychology behind emotional connection. It is a manuscript that combines personal experience, observations, and research, inspired by Rem Jaen D. Krafft's high school crush. Not only does it provide a guide for teenagers and young adults, but it also encourages readers to better understand attraction, communication, and emotional development. The final chapter examines how peer pressure, traditional high school cliques, fear of rejection, and fear of intimacy may influence societal norms, emotional contagion, and relationship formation …

Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie

Publications and Research

The emergence of large language models has precipitated a fun damental disruption to higher education assessment. Conventional instruments are susceptible to AI-assisted completion, threatening construct validity across disciplines and institutional contexts. When submitted work reflects AI capability rather than student competency, the inferential chain from performance to qualifica tion is invalidated – a problem of design rather than detection. This systematic review makes two contributions. First, it theorises and grounds the distinction between AI-resistant assessment, which seeks to prevent or impede AI access through containment, and AI-resilient assessment, which assesses genuine human cogni tive performance of intrinsic educational value regardless …

Colonial Futures: Ngaio Marsh, War, And The End Of Empire, Heather M. Robinson

Publications and Research

Between the years of 1941 and 1945, Ngaio Marsh published three New Zealand-focused whodunnits; all three of these stories explore the impacts of the Second World War to some degree. What is curious is not that Marsh wrote about the war, but her sustained focus on New Zealand and New Zealanders, given that Marsh’s fiction usually took place in London or its surrounding counties. It marks the impact on Marsh of the global conflict that was changing the world, and shaking the foundations of colonialism and modernity as they had been known before 1939. In this essay, I explore how …

Assessment Of Information Literacy Instruction In Reference: Applying Vanscoy’S Conceptual And Procedural Framework In Practice, Vanessa Arce

Publications and Research

The instructional aspect of reference work has long been acknowledged, especially in academic libraries. The current RUSA guidelines include helping users develop information literacy as a goal of reference. In this context, investigating the presence and nature of information literacy instruction can be used to assess the quality of reference services. This study applied Amy VanScoy’s conceptual/procedural framework for point-of-need instruction to a sample of chat reference transcripts at Lehman College, City University of New York. One of the assessment’s goals was to determine the prevalence of instruction and type of knowledge addressed in reference interactions. Another goal was to …

Highly Confident But Slightly Uncertain: A Long Overdue Reinvention Of The School Scientific Method, Teaching - Volume 4, Stephen Demeo

Publications and Research

In Volume 4, the last book of the series, I continue the argument for greater parity between conceptual knowledge—the "what" of science—and methodological knowledge—the "how" of science—but in the context of teacher instruction. To this end, two literature reviews are presented: One on how students build confidence, specifically regarding the reliability or consistency of measurement or results, and the other on scientific uncertainty. Research studies focusing on student misconceptions are summarized and organized from the elementary to the college level. These literature reviews describe invaluable ways for teachers to improve their instruction, while providing examples of experiments that can be …

Math 119: Math For Elementary School Teachers Syllabus, Seth Lehman

Open Educational Resources

OER course syllabus for Math 119, Math for Elementary School Teachers, at Queens College

Math 119: Math For Elementary School Teachers Instructor Guide, Seth Lehman

Open Educational Resources

OER instructor guide for Math 119: Math for Elementary School Teachers at Queens College

His 127 Microhistories: A Lens Into The Past — Apartheid In South Africa Syllabus, Marta Millar

Open Educational Resources

The microhistory course introduces students to the study of history by exploring a particular event, individual, or issue, and its legacy. Students will read both primary source documents and modern texts to examine how the topic under consideration was shaped by, and in turn shaped contemporary culture.

This syllabus is for a course focusing on the history of apartheid in South Africa. Students will analyze the political, social, economic, and cultural aspects of the apartheid era. This includes understanding how segregationist policies developed in South Africa, what political transformations led to the implementation of the apartheid system, how different policies …

Highly Confident But Slightly Uncertain: A Long Overdue Reinvention Of The School Scientific Method, Uncertainty And Error - Volume 3, Stephen Demeo

Publications and Research

Volume 3 explores the essential roles of uncertainty and error in scientific experimentation. It distinguishes between scientific error and scientific uncertainty: Scientific error refers to the difference between an experimental value and an accepted literature value, as well as the difference between data points in an x-y scatter plot and a predicted trendline. Scientific uncertainty, on the other hand, is associated with doubt arising from instrument limitations, variability within a data set, and psychological factors. Human error is set apart as mistakes or blunders, not to be conflated with scientific error.

Of utmost importance to the scientific investigator is the …

Highly Confident But Slightly Uncertain: A Long Overdue Reinvention Of The School Scientific Method, The X - Volume 1, Stephen Demeo

Publications and Research

In Volume 1, I critique the traditional School Scientific Method—an oversimplified, underdeveloped, and short, stepwise process—and argue for a more authentic, detailed, and rigorous approach to experiment-based scientific inquiry in education. I briefly explain the historical roots of the School Scientific Method, its benefits in increasing the exposure of experimental science to the masses, and its limitations in fostering more authentic scientific thinking and experimental practice.

In place of this traditional and problematic method, I introduce a graphic organizer called sciXpsy to foster both big-picture and detailed scientific thinking. The heuristic combines scientific concepts and methodology with the psychology of …

Highly Confident But Slightly Uncertain: A Long Overdue Reinvention Of The School Scientific Method, Confidence - Volume 2, Stephen Demeo

Publications and Research

Focusing on the psychology of empirical science, Volume 2 is an in-depth exploration of how students can build confidence in scientific data. Central to the text are twelve Confidence Indicators, a comprehensive set of approachable strategies and methodologies that help investigators produce, evaluate, and argue for reliable and valid empirical data. They include:

Good (and Ethical) Laboratory Practices

Repetition

Peer Replication/Review

Secondary Tests

Comparisons with Standards

Plots and Patterns

Conceptual Support

External Data Sources

Precision

Accuracy

Checking Calculations

Redesign/What-If Ideas

This volume includes numerous school science experiments that demonstrate how these indicators are applied across a wide range of educational …

Syllabus: Engl 1010 English Composition I, Sarah C. Bonanno

Open Educational Resources

This is a syllabus for English Composition I (ENGL 1010 FYSA) taught at Brooklyn College during the Fall 2026 semester. This course teaches students concrete and transferable writing skills through the genres of literacy narrative, argumentative essays, and comparative writing.

Chi Meta-Project Ecosystem Overview - Spring 2026, David B. Smith

Publications and Research

This paper offers a high-level account of the Center for Holistic Integration’s (CHI) meta-project ecosystem as visualized in the included system map. CHI provides an organizational structure framed around persistent meta-projects that support and extend individual initiatives across curriculum, scholarly and applied research, infrastructure, artistic production, AI development, cultural inquiry, and external partnerships. Rather than presenting the map as a static inventory of projects, the paper examines how its core domains function as living systems through which knowledge, tools, documentation, participants, and collaborations can accumulate over time. It also considers how CHI-mediated connectivity, institutional integration, and external funding allow the …

Art History Zine, Estelle Artus

Open Educational Resources

Open Assignment

Laminarin-Loaded Solid-In-Oil Nanodispersion For Enhanced Non-Invasive Transdermal Immunization, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie C. Wakabayashi, Noriho J. Kamiya, Muhammad Moniruzzaman, Masahiro Goto

Publications and Research

Simple and non-invasive transdermal vaccination is an attractive alternative to conventional injection-based immunization. However, the effectiveness of transdermal vaccines is often constrained by the stratum corneum barrier. Although the use of solid-in-oil (S/O) nanodispersion technology has successfully facilitated skin permeation to induce an immunological response, the antibody titers remain suboptimal. Herein, a dectin-1 selective ligand, laminarin, was used as an immunostimulatory adjuvant to enhance the immune response. S/O nanodispersions loaded with laminarin and ovalbumin (OVA) were systematically developed and characterized in terms of particle size, in vitro OVA release behavior, and skin permeation performance using excised mouse skin. In vivo …

The Parent Trip, Jessie Daniels

Publications and Research

This one-hour solo show propels the audience from 1970s Texas to 1990s New York City. In this hilarious and heartbreaking story, Jessie Daniels tells what it means to be raised to become a 'nice white lady.' When she rejects that to embrace the magic of queerness under a disco ball, she decides to write about it, and nearly loses everything.

Past Present, & Future: Bushwick Inlet Redevelopment, Aaryan Nair

Publications and Research

This report examines how ecosystem structure, hydrology, and material flows in Williamsburg, Brooklyn have changed from pre-colonial conditions to the present and how they are expected to evolve under future climate change. Prior to European colonization, the landscape functioned as a forest–wetland mosaic with high infiltration capacity, slow water movement, and strong nutrient retention. These conditions supported stable aquatic ecosystems and minimized pollutant transport to the East River.

Modern urbanization has fundamentally altered this system. Impervious surfaces and engineered drainage systems have shifted hydrology from infiltration-dominated to runoff-dominated pathways, producing rapid “flashy” flows and reducing water residence time.

Storm events …

Balancing Our Capacity To Serve: A Phenomenological Exploration Of Black Women Navigating Personal, Professional, And Community Leadership Roles, Shemeka K. Brathwaite

Student Theses

This phenomenological study explores the lived experiences of Black women community leaders as they navigate a balance between their professional, personal, and community leadership roles. The research design uses the theoretical frameworks of Black Feminist Intersectionality and Role Theory, specifically addressing the cultural burdens imposed by the Strong Black Woman archetype, which adds additional role strain. The study began with a questionnaire completed by 54 Black women community leaders, followed by 20 in-depth, semi-structured interviews selected from this pool. The study’s key findings are illustrated in a Black Women’s Sustainable Community Leadership Framework. Black women community leaders exude high self-efficacy, …

Textbook Eco 2200: Principles Of Financial Management, Dorina Tila

Open Educational Resources

This is a full-length textbook project on ECO 2200: Principles of Financial Management. The textbook includes auxiliary materials, such as discussions, video lectures, multiple choice tests, as well as examples and case studies in excel with linked videos on showing the solution.

Making A Makerspace: The Innervate Lab As A Reimagined Technology Education Space, Raaghav Pandya, Euisuk Sung, Caroline Darin

Publications and Research

With the growing emphasis on creativity, collaboration, and reflective thinking in technology and design education, technology labs are expected to shift from technical priorities to open, collaborative spaces. Designed within an existing technology education facility, the paper explored what it means to “technology lab” that merges the technical with the reflective, the cultural with the material, and the innovative with the contemplative. This paper presents the intellectual and aesthetic journey of creating an innovative makerspace within a technology education context and explains how this work embodies a sustainable model for training future technology educators. Our approach was informed by the …

Open Materials For Ant-Psy 210, Sex And Culture, Melissa Zavala

Open Educational Resources

Sex and Culture explores the cultural construction of human sexuality from the framework of the individual in society. Students will examine the social learning of sexual behaviors, beliefs and practices. Analytic focus will include how culturally prescribed gender roles for men and women inform notions of right and wrong. Specific topics may include institutionalized gender inequality, marriage and the family, homophobia and other issues involved in the relationship between sex and culture. All topics will be considered from a historical and cross-cultural perspectives.