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A Novel Tcr Transgenic Model Reveals That Negative Selection Involves An Immediate, Bim-Dependent Pathway And A Delayed, Bim-Independent Pathway, Damian Kovalovsky, Mark Pezzano, Benjamin D. Ortiz, Derek B. Sant'angelo Jan 2010

A Novel Tcr Transgenic Model Reveals That Negative Selection Involves An Immediate, Bim-Dependent Pathway And A Delayed, Bim-Independent Pathway, Damian Kovalovsky, Mark Pezzano, Benjamin D. Ortiz, Derek B. Sant'angelo

Publications and Research

A complete understanding of negative selection has been elusive due to the rapid apoptosis and clearance of thymocytes in vivo. We report a TCR transgenic model in which expression of the TCR during differentiation occurs only after V(D)J-like recombination. TCR expression from this transgene closely mimics expression of the endogenous TCRα locus allowing for development that is similar to wild type thymocytes. This model allowed us to characterize the phenotypic changes that occurred after TCR-mediated signaling in self-reactive thymocytes prior to their deletion in a highly physiological setting. Self-reactive thymocytes were identified as being immature, activated and CD4loCD8lo. These cells …


Comprehensive Institutional Self-Study: For The Middle States Associations Of Colleges And Schools, Commission On Higher Education, February 2, 2010, Laguardia Community College Jan 2010

Comprehensive Institutional Self-Study: For The Middle States Associations Of Colleges And Schools, Commission On Higher Education, February 2, 2010, Laguardia Community College

Middle States

Includes Appendices to the Report.


Course Catalog 2010-2011, Laguardia Community College Jan 2010

Course Catalog 2010-2011, Laguardia Community College

Course Catalogs

No abstract provided.


Vigilante Justice: Prosecutor Misconduct In Capital Cases, Jeffrey Kirchmeier Jan 2010

Vigilante Justice: Prosecutor Misconduct In Capital Cases, Jeffrey Kirchmeier

Publications and Research

No abstract provided.


Legal Research As A Fundamental Skill: A Lifeboat For Students And Law Schools, Sarah Valentine Jan 2010

Legal Research As A Fundamental Skill: A Lifeboat For Students And Law Schools, Sarah Valentine

Publications and Research

No abstract provided.


Archives & Records In Armed Conflict: International Law And The Current Debate Over Iraqi Records And Archives, Douglas Cox Jan 2010

Archives & Records In Armed Conflict: International Law And The Current Debate Over Iraqi Records And Archives, Douglas Cox

Publications and Research

No abstract provided.


Legal Research As A Fundamental Skill: A Lifeboat For Students And Law Schools, Sarah Valentine Jan 2010

Legal Research As A Fundamental Skill: A Lifeboat For Students And Law Schools, Sarah Valentine

Publications and Research

No abstract provided.


Sex Education And Rape, Michelle Anderson Jan 2010

Sex Education And Rape, Michelle Anderson

Publications and Research

No abstract provided.


Medical Conscience And The Policing Of Parenthood, Richard Storrow Jan 2010

Medical Conscience And The Policing Of Parenthood, Richard Storrow

Publications and Research

No abstract provided.


When Your Attorney Is Your Enemy: Preliminary Thoughts On Ensuring Effective Representation For Queer Youth, Sarah Valentine Jan 2010

When Your Attorney Is Your Enemy: Preliminary Thoughts On Ensuring Effective Representation For Queer Youth, Sarah Valentine

Publications and Research

No abstract provided.


La Fábula Y La Vida: El Vigilante Rosendo Tello, Almudena Vidorreta Jan 2010

La Fábula Y La Vida: El Vigilante Rosendo Tello, Almudena Vidorreta

Graduate Student Publications and Research

No abstract provided.


Folk Concepts, Jay H. Bernstein Jan 2010

Folk Concepts, Jay H. Bernstein

Publications and Research

No abstract provided.


Introduction To Dominican Blackness, Silvio Torres-Saillant Jan 2010

Introduction To Dominican Blackness, Silvio Torres-Saillant

Publications and Research

This study is a reflection on the complexity of racial thinking and racial discourse in Dominican society.


Performance Management Process Report: John Jay College Goals & Targets 2010-2011, John Jay College Of Criminal Justice Jan 2010

Performance Management Process Report: John Jay College Goals & Targets 2010-2011, John Jay College Of Criminal Justice

Reports and Publications from John Jay College

No abstract provided.


The Trouble With Logins: The Challenges Of Online Identity, Steven Ovadia Jan 2010

The Trouble With Logins: The Challenges Of Online Identity, Steven Ovadia

Publications and Research

The article explores the challenges of multiple logins and discusses projects like OpenID and OAuth. It also discusses "Identity 3.0," the so-called next generation of identity management.


Navigating The Challenges Of The Cloud, Steven Ovadia Jan 2010

Navigating The Challenges Of The Cloud, Steven Ovadia

Publications and Research

The article discusses the advantages of cloud-based services as well as the issues presented when an institution does not have full control of its own data.


Finding Data Sets Online, Steven Ovadia Jan 2010

Finding Data Sets Online, Steven Ovadia

Publications and Research

The article reviews several Web sites including IPUMS, IPEDS, and Data.gov.


Realkeepen: Anglicisms In The German Hip-Hop Community, Matt Garley Jan 2010

Realkeepen: Anglicisms In The German Hip-Hop Community, Matt Garley

Publications and Research

No abstract provided.


Holocaust-Denial Literature: A Sixth Bibliography, John A. Drobnicki Jan 2010

Holocaust-Denial Literature: A Sixth Bibliography, John A. Drobnicki

Publications and Research

This bibliography is a supplement to five earlier ones that were published in the Bulletin of Bibliography. Holocaust denial is a body of literature that seeks to prove that the Jewish Holocaust did not happen. This bibliography includes both works about Holocaust denial and works of Holocaust denial.


Patterns Of Subnet Usage Reveal Distinct Scales Of Regulation In The Transcriptional Regulatory Network Of Escherichia Coli, Carsten Marr, Fabian J. Theis, Larry S. Liebovitch, Marc-Thorsten Hutt Jan 2010

Patterns Of Subnet Usage Reveal Distinct Scales Of Regulation In The Transcriptional Regulatory Network Of Escherichia Coli, Carsten Marr, Fabian J. Theis, Larry S. Liebovitch, Marc-Thorsten Hutt

Publications and Research

The set of regulatory interactions between genes, mediated by transcription factors, forms a species’ transcriptional regulatory network (TRN). By comparing this network with measured gene expression data, one can identify functional properties of the TRN and gain general insight into transcriptional control. We define the subnet of a node as the subgraph consisting of all nodes topologically downstream of the node, including itself. Using a large set of microarray expression data of the bacterium Escherichia coli, we find that the gene expression in different subnets exhibits a structured pattern in response to environmental changes and genotypic mutation. Subnets with fewer …


Ubiquitous Research: Integrating Library Resources Into Online Courses., Kate Lyons, Elisabeth Tappeiner Jan 2010

Ubiquitous Research: Integrating Library Resources Into Online Courses., Kate Lyons, Elisabeth Tappeiner

Publications and Research

Online learning is transforming the way colleges and universities offer credit bearing courses. Now students are able to finish some or all of a degree online, with courses and programs from the hard sciences to the humanities. Nevertheless, a college education is comprised of a variety of educational and social activities that extend beyond a discrete class. Classroom learning is enriched and supported by services across campus, from the writing center to tutoring services, to the library.

This article discusses the experience of librarians working in a small, urban community college in integrating library collections, reference services, and information literacy …


Lamar Hunt, John A. Drobnicki Jan 2010

Lamar Hunt, John A. Drobnicki

Publications and Research

Lamar Hunt was a founder of the American Football League, the owner of the Kansas City Chiefs, and a sports promoter who was inducted into three professional sports halls of fame.


Introductory Research For Inner-City Advanced Placement High School Students, Keith Muchowski Jan 2010

Introductory Research For Inner-City Advanced Placement High School Students, Keith Muchowski

Publications and Research

Instruction module:

Circumstances of the Instruction: This module is based on a collaborative effort between a college librarian working with two 11 111 grade Advanced Placement (AP) History and English teachers. Students are enrolled in both the English and History classes, making collaboration and curriculum coordination easier. An instructional librarian working in concert with classroom faculty is beneficial to students because many teachers are not fully aware of recent trends such as information storage and retrieval systems and Web-based search tools. Students taking this module are intelligent, score well on standardized aptitude tests, and receive better than average grades. Still, …


The Critical Aesthetics Of Disorder: A Porteña Crisis Of Size, Melissa Maldonado-Salcedo Jan 2010

The Critical Aesthetics Of Disorder: A Porteña Crisis Of Size, Melissa Maldonado-Salcedo

Publications and Research

In Argentina, contemporary notions of progress originate within the whitening projects of the nineteenth century. In this work I propose that the imprints of these Colonial modernization projects are still visible on the porteña body. For this reason I examine the Porteño fashion industry alongside the pervasive Barbie culture. I believe that Porteñas embody the national crisis of identity. I seek to pose the possibility — instead of arguing the fact — that the fashion industry's power over Porteñas (women who live in Buenos Aires Capital) toughened post the economic crisis of 2001. The reason for this is rooted in …


Review Of Forbidden Planet, Michael Adams Jan 2010

Review Of Forbidden Planet, Michael Adams

Publications and Research

Review of Fred McLeod Wilcox's Forbidden Planet: http://www.media-party.com/discland/2010/09/forbidden-planet-blu-ray.html


Review Of Flash Gordon, Michael Adams Jan 2010

Review Of Flash Gordon, Michael Adams

Publications and Research

Review of Mike Hodges' Flash Gordon: http://www.media-party.com/discland/2010/07/flash-gordon-bluray.html


Dilemmas In Contemporary Planning And State Of The Practice Of Ppgis, Laxmi Ramasubramanian Jan 2010

Dilemmas In Contemporary Planning And State Of The Practice Of Ppgis, Laxmi Ramasubramanian

Publications and Research

No abstract provided.


Performance Management Process Report: John Jay College Year End Results 2009-2010, John Jay College Of Criminal Justice Jan 2010

Performance Management Process Report: John Jay College Year End Results 2009-2010, John Jay College Of Criminal Justice

Reports and Publications from John Jay College

No abstract provided.


Arabic For Designers By Mourad Boutros, Saad D. Abulhab Jan 2010

Arabic For Designers By Mourad Boutros, Saad D. Abulhab

Publications and Research

No abstract provided.


The European Union Accession Process And Its Effects On Turkish Civil Society, Gulsah Senol Jan 2010

The European Union Accession Process And Its Effects On Turkish Civil Society, Gulsah Senol

Student Theses and Dissertations

No abstract provided.