Digital Commons Network^™

Development Of An Approach To Increase Drug Uptake To Bone Tumors Using Non-Invasive Mechanical Loading, Paolo E. Palacio

Dissertations and Theses

This thesis develops an approach to enhance drug delivery to bone tumors by implementing a non-invasive mechanical loading technique. An imaging protocol that characterizes the load-enhanced drug uptake is also presented. The long-term goal of this work is to develop a clinical protocol that enhances the delivery of therapeutic agents to bone tumors by utilizing load-bearing activity. This easy-to-implement approach could help increase drug uptake into the tumor interstitial fluid space as well as into tumor cells, thereby enhancing a drug's clinical effect while decreasing systemic drug dosage and unwanted side effects. This thesis details the process used to grow …

Effects Of Estrogen Loss On The Vascular Porosity In Rat Cortical Bone, Jessica D Levy

Dissertations and Theses

"Osteoporosis is a skeletal disease that currently affects 10 million Americans, and is characterized by low bone mass and increased skeletal fragility (National Osteoporosis Foundation, 2011). Estrogen loss, which begins during menopause, is the leading cause of osteoporosis in women. Recent research has focused on changes in cortical bone microporosity due to estrogen loss, which is important for bone health; load-induced interstitial fluid flow within the lacunar-canalicular porosity surrounding osteocytes is thought to play an important role in bone maintenance, while the vascular porosity provides a pressure relaxation mechanism for the fluid flow in the lacunar-canalicular porosity. Recent high-resolution micro-CT …

Transport Of Antibodies And Nanoparticles Across An In Vitro Blood-Brain Barrier, Lin Zhang

Dissertations and Theses

"The blood-brain barrier (BBB) is a dynamic interface between the blood circulation and the central nervous system (CNS). While it serves as a selective barrier to water and solutes to prevent the blood-borne toxins from entering into the brain tissue, it hinders the drug delivery to the CNS for the treatment of brain diseases. Recently therapeutic antibodies and a variety of drug-loaded nanoparticles (NPs) have been widely used to treat CNS disorders such as brain tumors, Alzheimer's disease and Parkinson's disease. To improve brain delivery efficacy of antibodies and NPs, it is necessary to quantify their transport parameters across the …

Towards A Better Monitoring Of Soil Moisture Using A Combination Of Estimates From Passive Of Microwave And Infrared Observations, Zulamet Z. Vega-Martinez

Dissertations and Theses

No abstract provided.

Usa Vs China; Energy Security Politics Challenges Of Peak-Oil And Climate Change, Tania Hoppe

Dissertations and Theses

"Energy is a critical basis for state survival. This thesis aims at examining the different energy-security strategies of the USA and China and the political means necessary to implement clean-energy development beyond marginal results. The success of China’s lead in its devotion to clean-energy production raises the question of what infrastructural and political challenges the US must overcome to further develop its clean energy industry. While China focuses on its competitive edge in the global energy market, can its domestic energy goals offset population density and addiction to coal? Despite economic competitiveness that comes with market globalization, society’s only means …

The Difficult Relationship Between Haiti And The Dominican Republic, Wilfred Morfa

Dissertations and Theses

No abstract provided.

The Implementation Of The Rights Of The Child; Transcending The Traditional Practice Of Child Marriage In Niger, Yemen, And Thailand, Evette Rivera

Dissertations and Theses

"Child marriage is a harmful traditional practice that affects approximately 60 million children around the globe. This thesis examines the different laws that protect children from this practice and analyzes its implementation in countries where traditional practices violate children’s rights. International provisions, such as the Convention on the Rights of the Child, charges state parties with the responsibility to protect their children. Each state has the capacity to transcend traditional practices and implement local laws that protect their children. This thesis claims that mobilization of advocacy groups is vital in promoting the well-being of children even when the norms established …

Mikhail Gorbachev And His Role In The Peaceful Solution Of The Cold War, Natalia Zemtsova

Dissertations and Theses

"The role of a political leader has always been important for understanding both domestic and world politics. The most significant historical events are usually associated in our minds with the images of the people who were directly involved and who were in charge of the most crucial decisions at that particular moment in time. Thus, analyzing the American Civil War, we always mention the great role and the achievements of Abraham Lincoln as the president of the United States. We cannot forget about the actions of such charismatic leaders as Adolf Hitler, Josef Stalin, Winston Churchill, and Franklin D. Roosevelt …

The Impact Of Domestic Politics On Foreign Policy Decision-Making In Turkish-American Relations, Sevda Ceren Ozgur

Dissertations and Theses

"This study is an analysis of the impact of public opinion on the foreign policy decisionmaking process in Turkish-American relations. The aim of the study is to understand the construction and the mobilization of public opinion, and its the impact on the decisionmakers. Turkey and the United States have a long history of friendship dating back to the late 18th century. Public opinion has had a substantial influence on Turkish-American relations. There are various actors, such as lobby groups and the media, involved in the construction and the mobilization of public opinion in both countries. Understanding how they work and …

State And Nation-Building, Stabilization, And Development In Afghanistan, Maedeh Asadzadeh Barzi

Dissertations and Theses

"Afghanistan is emerging from more than two decades of conflict, capped by a severe nationwide drought in 1999-2001, and faces a complex, interrelated set of political, administrative, economic, and social challenge. The objective of this study was to analyze Afghanistan's human development based on specific criteria such as economic inequality and poverty, corruption, public health and most specifically children and women's health. This thesis identifies Afghanistan's challenges and impediments to development and state-building in the past nine years. I further argue that Afghanistan was successful in economic and public health matters due to the institutions that were built at the …

Time Out Of Mind As Distant Past Beyond Memory; Bob Dylan And His "Late Style", Koji Matsudo

Dissertations and Theses

No abstract provided.

Synthesis And Characterization Of Pbte Quantum Dots, Faiza Anwar

Dissertations and Theses

No abstract provided.

Respectability And The Modern Jazz Quartet; Some Cultural Aspects Of Its Image And Legacy As Seen Through The Press, Carla Marie Rupp

Dissertations and Theses

"The Modern Jazz Quartet (MJQ) was a noted jazz ensemble whose original members—John Lewis (piano and director), Milt “Bags” Jackson (vibraphone), Ray Brown (bass) and Kenny “Klook” Clarke (drums)—first performed together in Dizzy Gillespie’s big band in 1946.1 Lewis (1920-2005), Jackson (1923-1999), Brown (1926- 2002), and Clarke (1914-1985) first recorded as a group, calling themselves the Milt Jackson Quartet, in 1951-2. By the time the first recordings of the group under the name Modern Jazz Quartet were released in 1952, Percy Heath (1923-2005) had already replaced Brown as bassist. By 1954, the group had begun performing regularly in nightclubs and …

Proteomic Analysis Of Human Mesenchymal Stem Cell Aging During Serial Sub-Culture, Pawan Kc

Dissertations and Theses

"Human mesenchymal stem cells (hMSCs) hold great potential for clinical applications in regenerative medicine. However, hMSCs occur at a very low frequency in bone marrow so the clinical use as cellular therapeutics requires suitable techniques for isolation and expansion. Furthermore, these cells can be expanded in vitro for only limited passage numbers before they reach a senescent state. Previous studies have shown that long term culture of hMSCs results in the decrease in proliferation rates, changes in genomic expressions, increase in cell sizes, and other morphological changes. Currently the mechanisms of hMSC aging and biomarkers associated with it have not …

Haitian Diaspora Impact On Haitian Socio-Political And Economic Development, Sharleen Rigueur

Dissertations and Theses

"There is a new perspective developing within the international community on Diasporas and their potential to assist in the development process of their country of origin. The discussion began from the realization that transnational flows of remittances from sending countries (core) to receiving countries (periphery) increasingly surpass donor contributions to developing countries. The argument further discusses different socio-economic strategies to use when diasporic communities residing in developed countries (core) are assisting their homeland (periphery). This paper will look at the Haitian Diaspora in the United States and its active transnational link to Haiti. Since the days of post-Duvalierism, the Haitian …

“‘Like A Helpless Animal"? Like A Cautious Woman: Joyce’S ‘Eveline,’ Immigration, And The Zwi Migdal In Argentina In The Early 1900s, M Laura Barberan Reinares

Publications and Research

No abstract provided.

Dominican Related Dissertations In The U.S.: An Analytical Approach (1939-2009), Sarah Aponte

Publications and Research

This article seeks to present an overview of Dominican-related dissertations produced in the United States from 1939 to 2009. All dissertations that are known to deal in any way with Dominican affairs have been included. Some factors explored include: 1) trends in the annual production of doctoral degrees; 2) characteristics of doctorate recipients, including race/ethnicity and gender; 3) significant topics, concepts, and institutions that have shaped this diverse list; and 4) the most popular fields of study and the most frequently attended institutions of higher education. Entries include highlights on seminal works, lesser-known important dissertations and feature essays that will …

Update On Cuba's Agricultural Sector, Mario A. Gonzalez-Corzo

Publications and Research

No abstract provided.

Personality Variables And Frequency Of Risk-Taking Across Five Domains, Yelena Khvatskaya

Student Theses and Dissertations

No abstract provided.

Review Of The Killing, Michael Adams

Publications and Research

Review of Stanley Kubrick's The Killing: http://www.media-party.com/discland/2011/10/the-killing-blu-ray.html

Reshaping To Serve Evolving Communities: Addressing Immigrant Needs In The Library, Jen Hoyer

Publications and Research

Libraries face evolving communities and must constantly reorient themselves to serve new needs. This article examines the impact of emerging immigrant communities on library services. It discusses the emergence of library services to immigrants and the diverse faces of these services, which may include foreign language collections, access to technology and connections with local services, as appropriately determined through community analysis. The Atwater Library and Computer Centre in Montréal, Québec is examined as a case study of community analysis informing service reorientation. This article will be useful for organizations working with immigrants or community service providers confronted with changing demographics.

The Cuny Academic Commons: Fostering Faculty Use Of The Social Web, Matthew K. Gold, George Otte

Publications and Research

This paper analyzes the implementation of an academic social network that connects faculty members, administrators, and graduate students in a multi-campus university system. Part of a new generation of university-sponsored virtual spaces that foreground social networking, the CUNY Academic Commons has fostered a growing community of members who use the site to collaborate with colleagues across the system. This paper describes the processes involved in creating the site and offers guidance to institutions considering similar projects.

Risk Clusters, Hotspots, And Spatial Intelligence: Risk Terrain Modeling As An Algorithm For Police Resource Allocation Strategies, Leslie W. Kennedy, Joel M. Caplan, Eric L. Piza

Publications and Research

The study reported here follows the suggestion by Caplan et al. (Justice Q, 2010) that risk terrain modeling (RTM) be developed by doing more work to elaborate, operationalize, and test variables that would provide added value to its application in police operations. Building on the ideas presented by Caplan et al., we address three important issues related to RTM that sets it apart from current approaches to spatial crime analysis. First, we address the selection criteria used in determining which risk layers to include in risk terrain models. Second, we compare the ‘‘best model’’ risk terrain derived from our analysis …

Digitizing Deliberation: Normative Concerns For The Use Of Social Media In Deliberative Democracy, Nicole M. Elias

Publications and Research

Deliberative democracy as a form of citizen engagement and social media as a means to achieving greater citizen engagement have both received considerable attention in recent years; however, little attention has been paid to the way deliberative democracy and social media function together. The central aim of this research is to highlight the normative considerations surrounding social media in a deliberative democratic process. To do this, the article uses Iris Marion Young's model of deliberative democracy that is rooted in inclusion, political equality, reasonableness, and publicity. Applying this model's normative values to the use of audience response systems demonstrates that …

Terrorism: A Guide To Resources, Karen Okamoto, Marta Bladek

Publications and Research

Prior to 9/11, terrorism was subject to political, scholarly, and media debates. A large body of literature on the topic reflected researchers’ long-standing interest in the topic. In the near decade since 9/11, terrorism and its threat have only gained urgency. This paper aims to provide a selected bibliography of resources, in print and electronic format, that focus on terrorism. Public and academic libraries have been providing access to terrorism-related resources, but no thematic bibliography has been published in professional journals since 2001. This guide aims to aid librarians in making decisions about developing and maintaining collections on the topic.

Learning Through Quests And Contests: Games In Information Literacy Instruction, Maura A. Smale

Publications and Research

Games-based learning is an innovative pedagogical strategy employed at all levels of education, and much research in education, psychology, and other disciplines supports its effectiveness in engaging and motivating students, as well as increasing student learning. Many libraries have incorporated games into their collections and program-ming. College and university libraries have begun to use games for information literacy and library instruction. Academic librarians use commercially-produced games, create their own games, and employ game principles and mechanics to enhance their tradi-tional instructional offerings. While there may be impediments to implementing games-based learning for information literacy, the promising benefits of this approach …

One Hand Does Not Catch A Buffalo: 50 Years Of Amazing Peace Corps Stories, Aaron Barlow

Publications and Research

Stories from Peace Corp workers based in Africa.

Getting Into Character: Cultivating Identities In A Teen-Theatre Peer-Education Program, Valerie A. Futch

Dissertations, Theses, and Capstone Projects

This study investigated the role of community theatre participation on adolescent and young adult identity development. The theatre program, known as The SOURCE, focuses on sex-education through a peer-education model. The experiences of young adults, who are now aged 18-34, were examined through interviews (N=20), identity maps (N=9), and a survey (N=64) in order to understand how participation in this group influenced their development. While much of the literature documents the successes of such programs while youth participate, few document the longer-term impacts of such participation (Saldaña, McCammon, Omasta, & Hines, 2011). Data reveal how such involvement informed the youths' …

Education Policy And The Mathematics Curriculum In New York City Middle Schools, 1958 To 2002, Joseph Valley

Dissertations, Theses, and Capstone Projects

This study investigates how mathematics education policy and curriculum in New York City changed over the period from 1958 through 2002. It looks at the events leading up to the 퉌new math era, the back to basics movement, and the Standards movement initiated by the National Council of Teachers of Mathematics (NCTM) in 1989. Since this period is bounded by two important pieces of legislation, the National Defense Education Act (NDEA),1958, and the No Child Left Behind Act (NCLB) 2001 an assessment of the arguments for and against the federal intervention in education is essential.

The research methodology used for …

Intergroup Dialogue: An Evaluation Of A Pedagogical Model For Teaching Cultural Competence Within A Framework Of Social Justice In Social Work Programs, Mayra Lopez-Humphreys

Dissertations, Theses, and Capstone Projects

A quasi-experimental, non-equivalent comparison group design with pre, post and follow-up survey data was used to evaluate the effectiveness of an intergroup dialogue intervention on bachelor of social work (BSW) students' levels of cultural competence and social justice behaviors. The sample of convenience consisted of 115 who identified as social-work majors and participated in diversity courses, 76 were intergroup dialogue participants (Site IGD) and 39 were not (Site non-IGD). Five specific questions were explored in the study.

All 115 participants completed Lum's (2007) Social Work Cultural Competencies Self-Assessment and the Confidence in Confronting Injustice Sub-Scale (Multi-University Intergroup Dialogue Research project …