Digital Commons Network^™

Which Biomarkers Reveal Neonatal Sepsis?, Kun Wang, Vineet Bhandari, Sofya Chepustanova, Greg Huber, Stephen O′Hara, Corey S. O′Hern, Mark D. Shattuck, Michael Kirby

Publications and Research

We address the identification of optimal biomarkers for the rapid diagnosis of neonatal sepsis. We employ both canonical correlation analysis (CCA) and sparse support vector machine (SSVM) classifiers to select the best subset of biomarkers from a large hematological data set collected from infants with suspected sepsis from Yale-New Haven Hospital's Neonatal Intensive Care Unit (NICU). CCA is used to select sets of biomarkers of increasing size that are most highly correlated with infection. The effectiveness of these biomarkers is then validated by constructing a sparse support vector machine diagnostic classifier. We find that the following set of five biomarkers …

Radical Cataloging: From Words To Action, Heather Lember, Suzanne Lipkin, Richard Jung Lee

Urban Library Journal

Radical cataloging seeks to give a voice to people and concepts that are difficult to access through library subject searches. This article will explore four areas of radical cataloging: cataloging rules and the inequities and hierarchical problems inherent in classification itself, the use of cataloging to further a cause, the challenges of language in subject headings; and cataloging efforts around unconventional collections, such as zines.

College Senate Minutes December 12, 2013, Bronx Community College Senate

BCC Governance Archives

Minutes for the meeting of the College Senate on December 12, 2013.

Can Financial Accounting Regulators And Standard Setters Get (And Stay) Ahead Of The Financial Engineers?, Jonathan Glover

Publications and Research

No abstract provided.

An Argument And Plan For Promoting The Teaching And Learning Of Neglected Tropical Diseases, Kevin M. Bonney

Publications and Research

Neglected tropical diseases constitute a significant public health burden, affecting over one billion people globally, yet this group of diseases is underrepresented in the appropriation of both monetary and intellectual capital for developing improved therapies and public health campaigns. The topic of neglected tropical diseases has been similarly marginalized in the biology classrooms of our nation’s high schools and colleges, despite offering an opportunity to teach and learn about a diverse area of microbiology with far-reaching public health, social, and economic implications. Discussed herein is an argument for increasing the representation of neglected tropical diseases in microbiology education as a …

Biome Q10 And Dryness, Chuixiang Yi, Daniel Ricciuto, George Hendrey

Publications and Research

Temperature sensitivity of soil respiration (Q₁₀) is a critical parameter in carbon cycle models with important implications for climate-carbon feedbacks in the 21st century. The common assumption of a constant Q₁₀, usually with a value of 2.0, was shown to be invalid by a previous model-data fusion study that reported biome-specific values of this parameter. We extend the previous analysis by demonstrating that these biome-level values of Q₁₀ also are a function of dryness (R² = 0.54). When tundra and cultivated lands are excluded, the correlation is much stronger (R² = 0.92). Therefore …

Microfluidic Generated Egf-Gradients Induce Chemokinesis Of Transplantable Retinal Progenitor Cells Via The Jak/Stat And Pi3kinase Signaling Pathways, Uchenna J. Unachukwu, Moira Sauane, Maribel Vazquez, Stephen Redenti

Publications and Research

A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is important to define the molecular and biochemical mechanisms guiding RPC motility. We have analyzed RPC expression of the epidermal growth factor receptor (EGFR) and evaluated whether exposure to epidermal growth factor (EGF) can coordinate motogenic activity in vitro. Using Boyden chamber analysis as an initial highthroughput screen, we determined that RPC motility was optimally stimulated by EGF concentrations in the range of 20-400ng/ml, with decreased stimulation …

Iterative Feature Removal Yields Highly Discriminative Pathways, Stephen O’Hara, Kun Wang, Richard A. Slayden, Alan R. Schenkel, Greg Huber, Corey S. O’Hern, Mark D. Shattuck, Michael Kirby

Publications and Research

Background We introduce Iterative Feature Removal (IFR) as an unbiased approach for selecting features with diagnostic capacity from large data sets. The algorithm is based on recently developed tools in machine learning that are driven by sparse feature selection goals. When applied to genomic data, our method is designed to identify genes that can provide deeper insight into complex interactions while remaining directly connected to diagnostic utility. We contrast this approach with the search for a minimal best set of discriminative genes, which can provide only an incomplete picture of the biological complexity. Results Microarray data sets typically contain far …

Dos Detection In Ieee 802.11 With The Presence Of Hidden Nodes, Joseph Soryal, Xijie Liu, Tarek Saadawi

Publications and Research

The paper presents a novel technique to detect Denial of Service (DoS) attacks applied by misbehaving nodes in wireless networks with the presence of hidden nodes employing the widely used IEEE 802.11 Distributed Coordination Function (DCF) protocols described in the IEEE standard [1]. Attacker nodes alter the IEEE 802.11 DCF firmware to illicitly capture the channel via elevating the probability of the average number of packets transmitted successfully using up the bandwidth share of the innocent nodes that follow the protocol standards. We obtained the theoretical network throughput by solving two-dimensional Markov Chain model as described by Bianchi [2], and …

Communication And Common Interest, Peter Godfrey-Smith, Manolo Martínez

Publications and Research

Explaining the maintenance of communicative behavior in the face of incentives to deceive, conceal information, or exaggerate is an important problem in behavioral biology. When the interests of agents diverge, some form of signal cost is often seen as essential to maintaining honesty. Here, novel computational methods are used to investigate the role of common interest between the sender and receiver of messages in maintaining cost-free informative signaling in a signaling game. Two measures of common interest are defined. These quantify the divergence between sender and receiver in their preference orderings over acts the receiver might perform in each state …

2114-2251_Nir_Gnirs, Michael C. Liu

Publications and Research

No abstract provided.

Assessing The Performance Of A Northern Gulf Of Mexico Tidal Model Using Satellite Imagery, Stephen C. Medeiros, Scott C. Hagen, Naira Chaouch, Jesse Feyen, Marouane Temimi, John F. Weishampel, Yuji Funakoshi, Reza Khanbilvardi

Publications and Research

Tidal harmonic analysis simulations along with simulations spanning four specific historical time periods in 2003 and 2004 were conducted to test the performance of a northern Gulf of Mexico tidal model. A recently developed method for detecting inundated areas based on integrated remotely sensed data (i.e., Radarsat-1, aerial imagery, LiDAR, Landsat 7 ETM+) was applied to assess the performance of the tidal model. The analysis demonstrates the applicability of the method and its agreement with traditional performance assessment techniques such as harmonic resynthesis and water level time series analysis. Based on the flooded/non-flooded coastal areas estimated by the integrated remotely …

0112+1703_Nir_Gnirs, Michael C. Liu

Publications and Research

No abstract provided.

An Apparent Angular Unconformity In Western Connecticut, Stanley Schleifer, Nazrul I. Khandaker, Adisa Charles, Hernando Martinez, Shirley Jackson, Chiemeka Ihebom

Publications and Research

The recent extension, to the north, of the U. S. Route 7 ‘superhighway’ in the town of Brookfield, Connecticut has involved the excavation of crystalline bedrock of lower Paleozoic to upper Proterozoic age in the area. The road cuts produced by this excavation have exposed some interesting features of structure and lithology. An outcrop, observed by the authors off the east side of route 7, at grid coordinates 41.482444 N, 73.415307 W is of particular interest. It appears, to the casual observer to be an angular unconformity. Maps and publications regarding this area of Western Connecticut support the likelihood of …

Predicting The Behavioral Impact Of Transcranial Direct Current Stimulation: Issues And Limitations, Archy O. De Berker, Marom Bikson, Sven Bestmann

Publications and Research

The transcranial application of weak currents to the human brain has enjoyed a decade of widespread use, providing a simple and powerful tool for non-invasively altering human brain function. However, our understanding of current delivery and its impact upon neural circuitry leaves much to be desired. We argue that the credibility of conclusions drawn with transcranial direct current stimulation (tDCS) is contingent upon realistic explanations of how tDCS works, and that our present understanding of tDCS limits the technique’s use to localize function in the human brain. We outline two central issues where progress is required: the localization of currents, …

A Primer For Mathematical Modeling, Marla A. Sole

Publications and Research

With the implementation of the National Council of Teachers of Mathematics recommendations and the adoption of the Common Core State Standards for Mathematics, modeling has moved to the forefront of K-12 education. Modeling activities not only reinforce purposeful problem-solving skills, they also connect the mathematics students learn in school with the mathematics they will use outside of school. Instructors have found mathematical modeling difficult to teach. To successfully incorporate modeling activities I believe that curricular changes should be accompanied by professional development for curriculum developers, classroom teachers, and higher education professionals. This article serves as an introduction to modeling by …

The American Association Of School Librarians (Aasl) Standards For The 21st Century Learner Lesson Plan Database, Christina Miller

Publications and Research

The American Association of School Librarians (AASL) Standards for the 21st Century Learner Lesson Plan Database (AASL Database) is a free, Open Access, interactive tool recently (2011) developed by the American Association of School Librarians, a division of the American Library Association, to assist librarians, teachers and other educators in implementing the AASL Standards for the 21st Century Learner (AASL Standards) and the Common Core State Standards. It is comprised of vetted, content-area lesson plans meant to provide excellent models to integrate AASL Standards across K-12 curricula; the platform also includes social networking features and a user portfolio. The AASL …

The Queer Dialectic Of Whitman’S Nation: "Let" In “Respondez”, Václav Paris

Publications and Research

This article considers Whitman's "Respondez" - perhaps his strangest poem. It seeks to explicate the poem by looking at his shifting use of the word "let." The article draws on studies of queer theory, nationalism, modernism, to reveal an unfamiliar and far more radical Whitman than we are familiar with.

Global Trends In Seasonality Of Normalized Difference Vegetation Index (Ndvi), 1982–2011, J. Ronald Eastman, Florencia Sangermano, Elia Axinia Machado, John Rogan, Assaf Anyamba

Publications and Research

A 30-year series of global monthly Normalized Difference Vegetation Index (NDVI) imagery derived from the Global Inventory Modeling and Mapping Studies (GIMMS) NDVI3g archive was analyzed for the presence of trends in changing seasonality. Using the Seasonal Trend Analysis (STA) procedure, over half (56.30%) of land surfaces were found to exhibit significant trends. Almost half (46.10%) of the significant trends belonged to three classes of seasonal trends (or changes). Class 1 consisted of areas that experienced a uniform increase in NDVI throughout the year, and was primarily associated with forested areas, particularly broadleaf forests. Class 2 consisted of areas experiencing …

Fast Quantitative Real-Time Pcr-Based Screening For Common Chromosomal Aneuploidies In Mouse Embryonic Stem Cells, Charlotte D'Hulst, Irena Parvanova, Delia Tomoiaga, Maria L. Sapar, Paul Feinstein

Publications and Research

Chromosomal integrity has been known for many years to affect the ability of mouse embryonic stem cells (mESCs) to contribute to the germline of chimeric mice. Abnormal chromosomes are generally detected by standard cytogenetic karyotyping. However, this method is expensive, time consuming, and often omitted prior to blastocyst injection, consequently reducing the frequency of mESC-derived offspring. Here, we show a fast, accurate, and inexpensive screen for identifying the two most common aneuploidies (Trisomy 8 and loss of chromosome Y) in genetically manipulated mESCs using quantitative real-time PCR (qPCR). Screening against these two aneuploidies significantly increases the fraction of normal mESC …

Wave Function For Time-Dependent Harmonically Confined Electrons In A Time-Dependent Electric Field, Yu-Qi Li, Xiao-Yin Pan, Viraht Sahni

Publications and Research

The many-body wave function of a system of interacting particles confined by a time-dependent harmonic potential and perturbed by a time-dependent spatially homogeneous electric field is derived via the Feynman path-integral method. The wave function is comprised of a phase factor times the solution to the unperturbed time-dependent Schrödinger equation with the latter being translated by a time-dependent value that satisfies the classical driven equation of motion. The wave function reduces to that of the Harmonic Potential Theorem wave function for the case of the time-independent harmonic confining potential.

Chimeric Rhinoviruses Displaying Mper Epitopes Elicit Anti-Hiv Neutralizing Responses, Guohua Yi, Mauro Lapelosa, Rachel Bradley, Thomas M. Mariano, Denise Elsasser Dietz, Scott Hughes, Terri Wrin, Chris Petropoulos, Emilio Gallicchio, Ronald M. Levy, Eddy Arnold, Gail Ferstandig Arnold

Publications and Research

Background: The development of an effective AIDS vaccine has been a formidable task, but remains a critical necessity. The well conserved membrane-proximal external region (MPER) of the HIV-1 gp41 glycoprotein is one of the crucial targets for AIDS vaccine development, as it has the necessary attribute of being able to elicit antibodies capable of neutralizing diverse isolates of HIV.

Methodology/Principle Findings: Guided by X-ray crystallography, molecular modeling, combinatorial chemistry, and powerful selection techniques, we designed and produced six combinatorial libraries of chimeric human rhinoviruses (HRV) displaying the MPER epitopes corresponding to mAbs 2F5, 4E10, and/or Z13e1, connected to an immunogenic …

Catalog 2013-2014, Kingsborough Community College

Course Catalogs

No abstract provided.

Transitions In Nirs-Type Denitrifier Diversity, Community Composition, And Biogeochemical Activity Along The Chesapeake Bay Estuary, Christopher A. Francis, Gregory D. O'Mullan, Jeffrey C. Cornwell, Bess B. Ward

Publications and Research

Chesapeake Bay, the largest estuary in North America, can be characterized as having steep and opposing gradients in salinity and dissolved inorganic nitrogen along the main axis of the Bay. In this study, the diversity of nirS gene fragments (encoding cytochrome cd1-type nitrite reductase), physical/chemical parameters, and benthic N2-fluxes were analyzed in order to determine how denitrifier communities and biogeochemical activity vary along the estuary salinity gradient. The nirS gene fragments were PCR-amplified, cloned, and sequenced from sediment cores collected at five stations. Sequence analysis of 96–123 nirS clones from each station revealed extensive overall diversity in this estuary, as …

Standards In Research And Academia: The Role Of Standards In Teaching Professional Skills At The City University Of New York, Angelo Lampousis

Publications and Research

Standards Developing Organizations (SDOs) are pairing up with academia to continue to break the barriers to standards education at the undergraduate level. In addition, SDOs are working with the research facilities of academic institutions in a public-private partnership to maintain standards technological relevancy and to find new opportunities to provide standardization to industry and government. This session provides several examples of relationships between SDOs, government, academic institutions, and SES, and describes the advances made from these relationships.

Tectonosedimentologic Significance Of The Upper Cretaceous Foreland Basin Siliciclastics: Western Interior, Usa, Nazrul I. Khandaker

Publications and Research

The Upper Cretaceous Frontier Formation exposed along the western margin of the western interior foreland basin is composed of clastic sediments that were deposited during the initial late Cretaceous transgressive-regressive phases of the Western Interior Seaway across Wyoming (Figure 1). Current study is aimed at providing attendees with the best practices associated with tectonic, lithofacies and sedimentologic interpretation of foreland basin sequences and emphasizing the need for utilizing field, structural, geochemical, and compositional data for reconstructing a viable scenario connected with foreland basin sedimentary packages. An attempt will be made to compare documented sedimentological findings with foreland basins located in …

Introduction To Gis Using Open Source Software, 4th Ed, Frank Donnelly

Open Educational Resources

This tutorial was created to accompany the GIS Practicum, a day-long workshop offered by the Newman Library at Baruch College CUNY that introduces participants to geographic information systems (GIS) using the open source software QGIS. The practicum introduces GIS as a concept for envisioning information and as a tool for conducting geographic analyses and creating maps. Participants learn how to navigate a GIS interface, how to prepare layers and conduct a basic geographic analysis, and how to create thematic maps. This tutorial was written using QGIS version 1.8 "Lisboa", a cross-platform (Windows, Mac, Linux) desktop GIS software package.

Remote Sensing Of Soil Moisture In Vineyards Using Airborne And Ground-Based Thermal Inertia Data, Aiman Soliman, Richard J. Heck, Alexander Brenning, Ralph Brown, Stephen Miller

Publications and Research

Thermal remote sensing of soil moisture in vineyards is a challenge. The grass-covered soil, in addition to a standing grape canopy, create complex patterns of heating and cooling and increase the surface temperature variability between vine rows. In this study, we evaluate the strength of relationships between soil moisture, mechanical resistance and thermal inertia calculated from the drop of surface temperature during a clear sky night over a vineyard in the Niagara region. We utilized data from two sensors, an airborne thermal camera (height ≈ 500 m a.g.l.) and a handheld thermal gun (height ≈ 1 m a.g.l.), to explore …

The Discrimination Power Of Structural Superindices, Matthias Dehmer, Abbe Mowshowitz

Publications and Research

In this paper, we evaluate the discrimination power of structural superindices. Superindices for graphs represent measures composed of other structural indices. In particular, we compare the discrimination power of the superindices with those of individual graph descriptors. In addition, we perform a statistical analysis to generalize our findings to large graphs.

Stochastic Dea With A Perfect Object And Its Application To Analysis Of Environmental Efficiency, Alexander Vaninsky

Publications and Research

The paper introduces stochastic DEA with a Perfect Object (SDEA PO). The Perfect Object (PO) is a virtual Decision Making Unit (DMU) that has the smallest inputs and greatest outputs. Including the PO in a collection of actual objects yields an explicit formula of the efficiency index. Given the distributions of DEA inputs and outputs, this formula allows us to derive the probability distribution of the efficiency score, to find its mathematical expectation, and to deliver common (group–related) and partial (object-related) efficiency components. We apply this approach to a prospective analysis of environmental efficiency of the major national and regional …