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Consequences Of Oxidative Dna Damage: Base-Pair Dissociation, Singlet Oxygenation And Dna-Protein Crosslinking, May Myat Moe Feb 2025

Consequences Of Oxidative Dna Damage: Base-Pair Dissociation, Singlet Oxygenation And Dna-Protein Crosslinking, May Myat Moe

Dissertations, Theses, and Capstone Projects

8-Oxo-2′-deoxyguanosine (OG) is a common DNA lesion resulting from oxidatively generated damage and pairs with complementary cytidine (C) in Watson Crick base-pairing within duplex DNA. The WC-OG·C lesion, if not recognized or repaired, not only leads to G⋅C→T⋅A transversion mutations (through Hoogsteen (HG) base pairing of OG⋅A), but also renders the base pair being more vlunerable to ionizing radiation and singlet oxygen (1O2) damage. Leveraging on our previous accomplishments on the study of gas-phase reactions of 1O2 with 2′-deoxyguanosine radical cations, my research thesis expanded to the investigation of reaction dynamics of 9-methyl-8-oxoguanine (9MOG) radical cations. The experiments of following …


Investigating Dna Damage Caused By Reactive Oxygen And Nitrogen Species Via Guided-Ion-Beam Scattering And Computational Techniques, Jonathan Benny Feb 2025

Investigating Dna Damage Caused By Reactive Oxygen And Nitrogen Species Via Guided-Ion-Beam Scattering And Computational Techniques, Jonathan Benny

Dissertations, Theses, and Capstone Projects

Among DNA nucleobases, guanine (G) is the primary target for one-electron ionization and oxidation, generating G●+ through various processes, including photooxidation, electrocatalytic oxidation, DNA-binding transition metals, ionizing radiation, and photolysis. This is due to the low adiabatic ionization potential and oxidation potential of guanine. Electron holes from other nucleobases can move to guanine, proving that G●+ production traps oxidative DNA damage. G●+ formation can exacerbate DNA damages and cause secondary reactions from reactive oxygen species (ROS) and reactive nitrogen species (RNS) during pathological processes. The following three projects were conducted using a customized electrospray ionization (ESI) guided-ion-beam tandem mass spectrometer, …


Myth, Mayhem, And Pseudo-Democracy: The Role Of Political Myths In Mobilizing Nationalist Populist Movements And Political Extremists, Stephon J. Boatwright Feb 2025

Myth, Mayhem, And Pseudo-Democracy: The Role Of Political Myths In Mobilizing Nationalist Populist Movements And Political Extremists, Stephon J. Boatwright

Dissertations, Theses, and Capstone Projects

This body of research analyzes the enduring impact of political myth in nationalist populism and extremist movements. The rise of Western nationalist parties and acts of terror in the early 21st century gave life to this project. The manuscript advances two theories regarding political myths and their relationship to far right radicalism. First, nationalist myths—sprawling political worldviews whose dogmatic tenets are resistant to empirical critique and rational refutation—function as ideological constructs. They fictionalize the causes of events and serve to recruit adherents to authoritarian causes. Myths are continually reworked to address factual inaccuracies, failed predictions, and evolving social developments, while …


A Benjaminian Rumination Of Grasses And Tomatoes In Contemporary Anatolian Film, Ceren Izci Feb 2025

A Benjaminian Rumination Of Grasses And Tomatoes In Contemporary Anatolian Film, Ceren Izci

Dissertations, Theses, and Capstone Projects

This thesis interprets the intersection of history, ecology, and politics through two contemporary Anatolian films: Nuri Bilge Ceylan’s About Dry Grasses and Murat Fıratoğlu’s One of These Days When Hemme Dies. We focus on the films’ portrayal of social relations and relationships to other living beings through interpreting the temporal layers and historical tensions present in the plots of the films. We introduce the paper by pondering over the question of whether these films are political. Drawing on Walter Benjamin’s concepts of “first nature” and “second nature”, the first chapter introduces the philosophical framework for understanding the connection between …


Comprehensive Data-Driven Analysis Of Nyc Real Estate Transactions: Insights Into Pricing Dynamics, Neighborhood Evolution, And Socioeconomic Influences, Ruiming Xu Feb 2025

Comprehensive Data-Driven Analysis Of Nyc Real Estate Transactions: Insights Into Pricing Dynamics, Neighborhood Evolution, And Socioeconomic Influences, Ruiming Xu

Dissertations, Theses, and Capstone Projects

This project provides a comprehensive analysis of New York City’s real estate market, focusing on its historical evolution, shifting demographics, and the significant impact of the COVID-19 pandemic on housing trends. Utilizing data from trusted sources like Zillow, the NYC Department of Finance, and the U.S. Census Bureau, the study investigates how property values have changed over time, highlights neighborhoods undergoing notable transformations, and identifies the economic, cultural, and social factors driving these changes. The research aims to reveal the complex forces shaping the market while offering insights into its future direction and the reasons behind current trends. A key …


A Prototype Online Platform For Exploring Post-Covid Academic Recovery In U.S. Public Schools: An Example From California Public Schools, Nicole Baz Feb 2025

A Prototype Online Platform For Exploring Post-Covid Academic Recovery In U.S. Public Schools: An Example From California Public Schools, Nicole Baz

Dissertations, Theses, and Capstone Projects

This project introduces a prototype online platform designed to analyze the effects of the COVID-19 pandemic on academic achievement in public schools and districts across the United States. Leveraging data from the Stanford Education Data Archive (SEDA) and the National Center for Education Statistics (NCES), the platform enables users to examine recovery rates as measured by standardized test scores. California serves as a proof-of-concept case study, demonstrating the platform's ability to explore recovery patterns in Reading Language Arts and Mathematics between 2019 and 2023. The platform provides interactive data visualizations and dashboards that facilitate analyses based on district size, resources, …


Differential Mechanisms Of Access In Working Memory: Comparing Global And Selective Retrieval, Jade M. Turbides Feb 2025

Differential Mechanisms Of Access In Working Memory: Comparing Global And Selective Retrieval, Jade M. Turbides

Dissertations, Theses, and Capstone Projects

Working memory (WM) is essential for numerous cognitive tasks, yet the mechanisms underlying selective access to specific subsets of its contents vs. global, nonselective access remain incompletely understood. Context-specific selection of individual items from WM has been found to be more time-consuming and error-prone than globally accessing all memory contents. This study investigates whether the performance costs of selective WM access arise primarily from demands on item-context binding memory. Previous research has suggested that only selective access relies on memory for item-context bindings whereas global access can solely rely on item memory. Across two experiments, we employed task paradigms that …


The Effects Of Irrelevant Parameters In Language Acquisition, Yukun Zhang Feb 2025

The Effects Of Irrelevant Parameters In Language Acquisition, Yukun Zhang

Dissertations, Theses, and Capstone Projects

This paper investigates the effects of sententially irrelevant syntactic information on language acquisition models and introduces a new variant of the variational learner (VL) called the early decision variational learner (EDVL). EDVL accelerates convergence by locking in parameter values once they reach a threshold, in contrast to VL’s continued adjustments until all parameter values reach threshold. Both learners are grounded in the generative approach to language acquisition. We examine both learners' responses when they only update their parameter values when the input contain the relevant information to determin the parameter value such as prepositions, wh-words, and auxiliary verbs. Chapter 1 …


The Psychophysiology Of Primary And Secondary Variants Of Psychopathic Traits In Youth, Ines Guariguata Feb 2025

The Psychophysiology Of Primary And Secondary Variants Of Psychopathic Traits In Youth, Ines Guariguata

Dissertations, Theses, and Capstone Projects

Psychopathy is a cluster of personality traits marked by a pervasive callousness, lack of shame or remorse, deceitfulness, a persona of confidence and charm, shallow emotional connection, general lack of insight into their actions, and an absence of anxiety (Glenn & Raine, 2014; Hare, 2003). Research suggests that there are distinct etiological pathways to the development of psychopathic traits and that their responses to treatment are different (Craig et al., 2021; Yildrim & Derksen, 2015; Fleming et al., 2023). Primary variants show a low-fear, low-anxiety profile during stress, and have a genetic basis (Craig et al., 2021; Yildrim & Derksen, …


Banking And The Wider Economy: Essays On Capital And Cross-Border Risks, Morgan Hunt Feb 2025

Banking And The Wider Economy: Essays On Capital And Cross-Border Risks, Morgan Hunt

Dissertations, Theses, and Capstone Projects

Chapter 1: This paper examines the impact of growth in the banking industry’s capital and assets on real output growth at both aggregate and industry levels using a short-run factor-augmented vector autoregression (FAVAR) model across 19 NAICS two-digit industries from 2007Q1 to 2019Q4. Results reveal that changes in capital growth significantly affect output growth in the Manufacturing and Finance industries, while changes in risk-weighted assets impact the Construction, Manufacturing, Real Estate, and Transportation industries. Conversely, output growth in the Manufacturing and Retail Trade industries influences capital growth, while Wholesale Trade output growth affects risk-weighted assets. These relationships are robust …


Advancing Structural And Textual Guidance In Medical Image Segmentation: A Journey From Fully Supervised To Weakly Supervised Learning, Jiaqi Yang Feb 2025

Advancing Structural And Textual Guidance In Medical Image Segmentation: A Journey From Fully Supervised To Weakly Supervised Learning, Jiaqi Yang

Dissertations, Theses, and Capstone Projects

Accurate segmentation of medical images is essential for clinical diagnosis, enabling precise measurement, monitoring, and analysis of anatomical structures. While advanced models have achieved impressive per-pixel performance under fully supervised settings, ensuring fine-scale structural completeness remains a challenge, particularly for complex biomedical structures where coherence and integrity are critical. Fully supervised methods also face inherent limitations due to their reliance on extensive pixel-level annotations. These annotations are labor-intensive, costly, and often suffer from low inter-expert agreement, especially in cases like OCT images where small lesions and unclear boundaries make precise labeling difficult. This underscores the challenge of acquiring large, high-quality …


Inherited Wounds: Generational Trauma In Postcolonial Film And Narrative Fiction Of The Global South, Sabrina Testi Melgarejo Feb 2025

Inherited Wounds: Generational Trauma In Postcolonial Film And Narrative Fiction Of The Global South, Sabrina Testi Melgarejo

Dissertations, Theses, and Capstone Projects

The theorization of trauma in literary studies emerged in the 1990s, evolving from its physiological origins to a multidisciplinary framework encompassing literature, psychology, and history. However, classical trauma theory, rooted in Western scholarship and focused on singular traumatic events, has been criticized for its limitations in addressing collective and ongoing trauma in non-Western contexts. This thesis responds to a call for a more inclusive approach to trauma studies, examining how multi-generational and cultural trauma is represented in non-Western postcolonial films and literature from the Global South, including works from the Philippines, Sri Lanka, Cuba, Angola, Mozambique, Vietnam, and Lebanon.

The …


Taming Biological Complexity Through The Use Of Symmetries, Luis A. Álvarez-García Feb 2025

Taming Biological Complexity Through The Use Of Symmetries, Luis A. Álvarez-García

Dissertations, Theses, and Capstone Projects

The study of biological systems is, inherently, the study of very complex systems. This is essentially due to the fact that they are made up of numerous, often very complicated, interactions between an extensive number of components. Often necessitating an abundance of quantitative parameters and details for a precise description. The human brain for ex- ample, consisting of ∼ 80 billion neurons with ∼ 800 to 100 trillion connections between them, each of them depending on a large set of parameters. Even simpler examples such as bacterial organisms, such as E. coli and B. subtilis, which we focus on …


Novel Alchemical Methodologies For Modeling Molecular Binding, Solmaz Azimi Feb 2025

Novel Alchemical Methodologies For Modeling Molecular Binding, Solmaz Azimi

Dissertations, Theses, and Capstone Projects

Molecular recognition is fundamental to all biological and biochemical processes. Understanding the interactions between molecules is the foundation for drug discovery and development, for understanding biological processes, and for the design of biosensors and nanomaterials. There is tremendous interest in the development of computer models to predict molecular association equilibria. In structure-based drug discovery enterprises, predicting the strength and selectivity of a small molecule to a biological target can advance target identification, aid ligand design, and accelerate high-throughput screening of drug compounds. This work focuses on free energy models, a class of computational methodologies grounded on the fundamental physical and …


Beauty Comes With A Price: But How Much Is It Worth It, Fabliha Afia Feb 2025

Beauty Comes With A Price: But How Much Is It Worth It, Fabliha Afia

Dissertations, Theses, and Capstone Projects

The global skincare market, valued at 104.24 billion dollars in the year 2022, is very heterogeneous, ranging from prestige brands to more drugstore types. Even when the same key ingredients are present, the latter often sells for much higher due to branding and packaging and the aura of prestige created. This capstone project entitled "Beauty comes with a price: but how much is it worth?" investigates if such higher costs are justified due to superior quality or are driven by non-functional factors. It systematically compared the high-end versus drugstore skincare products in categories like sunscreens, serums, and exfoliants with respect …


Quantifying The Individual Bilingual Experience Through A Lens Of Language Dominance, Leeann Stover Feb 2025

Quantifying The Individual Bilingual Experience Through A Lens Of Language Dominance, Leeann Stover

Dissertations, Theses, and Capstone Projects

This article-based dissertation addresses some of the issues regarding the multifaceted nature of bi/multilingualism, focusing on the significance of individual variation in the measurement of language dominance. While age of later-acquired languages has traditionally been used to classify bilingual speakers into early and late bilinguals, the construct of language dominance has emerged as an additional criterion of classification. However, despite its utility in capturing dimensions of language experience beyond age of acquisition, the construct of language dominance has its own challenges of measurement and individual variation.

This dissertation focuses on two open-ended challenges in the quantification of language dominance: how …


Guaqueras And Campesinas In Western Boyacá, Colombia, María F. Buitrago Feb 2025

Guaqueras And Campesinas In Western Boyacá, Colombia, María F. Buitrago

Dissertations, Theses, and Capstone Projects

Guaqueras and Campesinas in Western Boyacá (https://mariabuitsan.github.io/guaqueras-ycampesinas/) is a digital memory project chronicling the lives and labors of women residing in the emerald-producing municipalities of Colombia. The project explores women’s remarkable resilience amidst a historically extractive and patriarchal emerald economy by co-creating an online collection enriched with various sources such as interviews, photos of artifacts, and audio from fieldwork. The collection uses Dédalo, a free and open-source Cultural Heritage and Management System, to store, digitize, and index all the unedited material and presents a selection of these resources through a static website. The collection intends to illuminate and honor the …


Silver-Alloyed Cigs Thin-Film Solar Cells On Flexible Stainless-Steel Substrate, Zhi Huang Feb 2025

Silver-Alloyed Cigs Thin-Film Solar Cells On Flexible Stainless-Steel Substrate, Zhi Huang

Dissertations, Theses, and Capstone Projects

Our dissertation demonstrates the optimization of ACIGS (Ag-Cu-In-Ga-Se) thin-film solar cells, achieving an efficiency of 20.4% through the combined effects of silver incorporation and alkali metal post-deposition treatment (PDT). The incorporation of 2.8% Ag into the CIGS lattice enhanced crystal quality, reduced disorder, and widened the bandgap by 0.103 eV, as evidenced by a significant reduction in Urbach energy. These improvements resulted in stronger light absorption, increased carrier generation, and enhanced photovoltaic parameters, including a short-circuit current density Jsc of 35.31 mA/cm², an open-circuit voltage Voc of 0.74 V, and a fill factor (FF) of 75.8%. PDT using rubidium fluoride …


China And Russia In Africa: The Case Of Togo, Eli J. Messanh Feb 2025

China And Russia In Africa: The Case Of Togo, Eli J. Messanh

Dissertations, Theses, and Capstone Projects

This thesis examines the impacts of China and Russia’s influence in Africa and focuses on the case of Togo, looking into how the increase in China and Russia’s presence on the continent affects the latter, the similarities and differences of their engagements, and what Africans as well as Togolese think of the proliferation of China and Russia’s influence in their countries. Using a mixed-methods approach with discussions and in-depth literature reviews, the research concludes that China and Russia’s relations vis à vis African countries produce both positive and negative effects, however, the negative effects outweigh the positive. It is therefore …


Testing Toxicity: Two Approaches To Toxicity Detection, Nelson E. Jarrin Feb 2025

Testing Toxicity: Two Approaches To Toxicity Detection, Nelson E. Jarrin

Dissertations, Theses, and Capstone Projects

The current online environment is increasingly being polluted by polarization, echo chambers, and a lack of constructive dialogue between individuals with differing viewpoints. Social media algorithms, while intended to personalize user experiences and marketing areas, have been heavily criticized for inadvertently amplifying extremist content and contributing to the spread of toxic commentary. The current state of the internet hinders productive conversations, fuels misinformation, entices disinformation and contributes to online and offline societal division. This is fueled by algorithms that can create echo chambers and by the anonymity given by online platforms. While tools like the Perspective API exist to identify …


The Cuny Community Colleges Consortium: Workforce Development Transformation Through Systems Change, Daniel Matishek, Lori Conkling Jan 2025

The Cuny Community Colleges Consortium: Workforce Development Transformation Through Systems Change, Daniel Matishek, Lori Conkling

Open Educational Resources

In 2021, Queensborough Community College (QCC) was awarded a $5 million Strengthening Community Colleges (SCC) Training Grant from the United States Department of Labor to develop and oversee a Consortium of six community colleges – named the CUNY Community Colleges Consortium (CUNYCCC) - within the City University of New York (CUNY), with the goal of transforming the University’s workforce development programs and addressing the needs of unemployed New York City (NYC) residents impacted by Covid-19. CUNYCCC offered participants workforce pathways in the labor sectors of education, technology, and health. Each college enhanced their workforce training programs through a variety of …


Does College Guarantee Economic Mobility?: Incorporating Lost In-Kind Benefits Into The Calculation, Amy S. White Jan 2025

Does College Guarantee Economic Mobility?: Incorporating Lost In-Kind Benefits Into The Calculation, Amy S. White

Publications and Research

Average salaries of college graduates are higher than salaries of those without degrees. However, the experience of graduating and out-earning the income requirements for in-kind or entitlement benefits like Medicaid, public assistance, Supplemental Nutritional Assistance Plan, and/or Section 8 housing vouchers are not taken into consideration in any mobility calculation nor are students prepared to lose their benefits. Teaching at an urban commuter school in a financially disadvantage borough, I have identified a gap in the research literature and supportive services for these low-income students. This opinion piece further describes the problem and highlights areas for future action and research.


Minor Role Iii: Youth Under Age 18 And New York City Violence, Jeffrey A. Butts, Gina Moreno Jan 2025

Minor Role Iii: Youth Under Age 18 And New York City Violence, Jeffrey A. Butts, Gina Moreno

Publications and Research

Researchers at the John Jay College Research and Evaluation Center analyzed NYPD arrest data from 2006 to 2024 to assess trends in felony assault, felony robbery, and felony weapon offenses across age groups. The study examined whether New York’s “Raise the Age” law, which shifted most youth under 18 out of adult court, influenced violent crime patterns. Although arrests rose across all age groups following the COVID-19 pandemic, trends among youth under 18 generally mirrored those of older age groups. The findings suggest no clear evidence that the law caused a youth-specific increase in violent crime.


Centering Equity In An Ai-Generated Literacy Read Aloud Lesson Plan Brought To Life By Preservice Teachers, Denise Farrelly Jan 2025

Centering Equity In An Ai-Generated Literacy Read Aloud Lesson Plan Brought To Life By Preservice Teachers, Denise Farrelly

Open Educational Resources

This resource is a series of in-class activities geared toward preservice teachers (PSTs) focused on how to center equity in their instructional planning and lesson implementation. PSTs will be able to use a generative AI tool to select an appropriate read aloud book and create the framework for a literacy lesson plan that stems from their own students’ interests. While AI will generate the learning objectives, standards, and basic procedures for the lesson plan, the PSTs will integrate the student-centered and culturally-responsive elements such as meaningful and engaging questioning, activities, and assessments. PSTs will consider these factors as they revise …


Synergizing Tqm, Jit, And Green Supply Chain Practices: Strategic Insights For Enhanced Environmental Performance, Aamir Rashid, Rizwana Rasheed, Noor Aina Amirah Jan 2025

Synergizing Tqm, Jit, And Green Supply Chain Practices: Strategic Insights For Enhanced Environmental Performance, Aamir Rashid, Rizwana Rasheed, Noor Aina Amirah

Publications and Research

Background: This study examined the role of total quality management, just-in-time, and green supply chain management practices to improve environmental performance. Methods: Data from 207 manufacturing industry respondents from a developing economy were tested through a quantitative method using PLS-SEM with the help of SmartPLS to validate the measurement model. Results: The results show that just-in-time significantly impacts total quality management and green supply chain management practices. Similarly, total quality management significantly affects environmental performance. However, just-in-time insignificantly affects the environment. Likewise, total quality management is insignificant and negatively affects green supply chain practices. Conclusion: This research provides practical insight …


Transform A Library Corner Into A Social Learning Space, Junli Diao Jan 2025

Transform A Library Corner Into A Social Learning Space, Junli Diao

Open Educational Resources

This library project proposal outlines the essential steps to convert a library corner into a leisure reading space. The proposal includes opening narrative, justifications, work plan, outcome assessment, and budget estimation.


Gender Equity In Municipalities: Understanding Local Policy Priorities, Maria J. D’Agostino, Nicole M. Elias, Nicole Dimaria Jan 2025

Gender Equity In Municipalities: Understanding Local Policy Priorities, Maria J. D’Agostino, Nicole M. Elias, Nicole Dimaria

Publications and Research

The purpose of this research is to examine policy priorities of municipal legislation designed to promote gender equity. We ask the following research question: How does municipal policy address gender equity? To answer this question, we identify New York City legislation that targets gender equity passed under the DeBlasio administration (2014–2022). Using Atlas.TI, legislation is organized around The New York City Commission on Gender Equity’s goals to identify policy priorities. Our findings indicate that despite progressive policy efforts, policy priorities remain focused on gender stereotypes and long-standing issues, particularly sexual harassment and violence.


Cogenerative Dialogues: Let’S Talk Computational Thinking, Linda Noble, Malgorzata Powietrzynska, Gabrielle Figueroa Jan 2025

Cogenerative Dialogues: Let’S Talk Computational Thinking, Linda Noble, Malgorzata Powietrzynska, Gabrielle Figueroa

Open Educational Resources

As Associate Adjunct Professors we (Linda and Malgorzata) have been co-teaching with graduate students for over 10 years at Brooklyn College’s School of Education. Recently, as part of CUNY’s Computing Integrated Teacher Education (CITE) initiative, we embarked on integrating computational thinking (CT) into our SEED 7507 course (Sociocultural and Developmental Approaches to Teaching and Learning in Diverse Classrooms). The course aimed at exploring theories of social and emotional learning, interpersonal interaction, culture, race, gender, role of language and literacy with implications for teaching and learning practices, planning and assessment. Incorporating CT involved new terminology, tools, and ways of teaching. Consequently, …


Schlichting Hist 103 Syllabus, Kara M. Schlichting Jan 2025

Schlichting Hist 103 Syllabus, Kara M. Schlichting

Open Educational Resources

No abstract provided.


An Exploration Of Collaboration Between School Psychologists And School Administrators, Marian C. Fish, Nathalis Wamba, Tom Matuza, Julie Cooperstone Jan 2025

An Exploration Of Collaboration Between School Psychologists And School Administrators, Marian C. Fish, Nathalis Wamba, Tom Matuza, Julie Cooperstone

Publications and Research

Prior research has highlighted strong benefits from having a collaborative environment within schools. However, there has been limited research regarding factors that can promote a collaborative relationship between two key professionals within the school environment: school administrators and school psychologists. The first purpose of this study was to examine the nature of collaboration between school psychologists and school administrators. The second purpose was to explore ways to facilitate and improve this interprofessional collaboration within the school to promote safe, equitable, and supportive school climates and positive student outcomes. Using a qualitative methodology, we collected and analyzed data from three focus …