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High-Affinity Naloxone Binding To Filamin A Prevents Mu Opioid Receptor–Gs Coupling Underlying Opioid Tolerance And Dependence, Hoau-Yan Wang, Maya Frankfurt, Lindsay H. Burns Feb 2008

High-Affinity Naloxone Binding To Filamin A Prevents Mu Opioid Receptor–Gs Coupling Underlying Opioid Tolerance And Dependence, Hoau-Yan Wang, Maya Frankfurt, Lindsay H. Burns

Publications and Research

Ultra-low-dose opioid antagonists enhance opioid analgesia and reduce analgesic tolerance and dependence by preventing a G protein coupling switch (Gi/o to Gs) by the mu opioid receptor (MOR), although the binding site of such ultra-low-dose opioid antagonists was previously unknown. Here we show that with approximately 200-fold higher affinity than for the mu opioid receptor, naloxone binds a pentapeptide segment of the scaffolding protein filamin A, known to interact with the mu opioid receptor, to disrupt its chronic opioid-induced Gs coupling. Naloxone binding to filamin A is demonstrated by the absence of [3H]-and FITC-naloxone binding in the melanoma M2 cell …


The Ticker, February 4, 2008 Feb 2008

The Ticker, February 4, 2008

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.


The Ethics Of Interrogation And The American Psychological Association: A Critique Of Policy And Process, Brad Olson, Stephen Soldz, Martha Davis Jan 2008

The Ethics Of Interrogation And The American Psychological Association: A Critique Of Policy And Process, Brad Olson, Stephen Soldz, Martha Davis

Publications and Research

The Psychological Ethics and National Security (PENS) task force was assembled by the American Psychological Association (APA) to guide policy on the role of psychologists in interrogations at foreign detention centers for the purpose of U.S. national security. The task force met briefly in 2005, and its report was quickly accepted by the APA Board of Directors and deemed consistent with the APA Ethics Code by the APA Ethics Committee. This rapid acceptance was unusual for a number of reasons but primarily because of the APA's long-standing tradition of taking great care in developing ethical policies that protected anyone who …


Course Catalog 2008-2009, Laguardia Community College Jan 2008

Course Catalog 2008-2009, Laguardia Community College

Course Catalogs

No abstract provided.


Angels And Demons: Christina Rossetti’S Goblin Market As A Social Critique Of The Victorian Ideal Of The “Angel In The House” And The Pre-Raphaelites’ Response To That Ideal, Melissa Adams Jan 2008

Angels And Demons: Christina Rossetti’S Goblin Market As A Social Critique Of The Victorian Ideal Of The “Angel In The House” And The Pre-Raphaelites’ Response To That Ideal, Melissa Adams

Theses and Dissertations

Christina Rossetti’s poem Goblin Market presents a subversive critique on the socially constructed dichotomy of Angel versus Demon as depicted in Pre-Raphaelite artwork, Dante Gabriele Rossetti’s poetry, and Coventry Patmore’s poem Angel in the House. An analysis of Goblin Market in relation to Patmore’s poem and the Pre-Raphaelite paintings The Annunciation, Ophelia, Lady Lilith, Circe Offering the Cup to Ulysses, and Sibylla Palmifera and Dante Gabriele Rossetti’s poems “Soul’s Beauty” and “Body’s Beauty” illustrate the ways in which Rossetti presents a counter-image that breaks down this socially constructed dichotomy. This is additionally supported by an exploration …


Teaching Law In A Multicultural, Multilingual Context, Pamela Edwards, Raquel Gabriel, Donna Lee, David Nadvorney Jan 2008

Teaching Law In A Multicultural, Multilingual Context, Pamela Edwards, Raquel Gabriel, Donna Lee, David Nadvorney

Publications and Research

No abstract provided.


Tr-2008008: Schur Aggregation For Linear Systems And Determinants, V. Y. Pan, D. Grady, B. Murphy, G. Qian, R. E. Rosholt, A. D. Ruslanov Jan 2008

Tr-2008008: Schur Aggregation For Linear Systems And Determinants, V. Y. Pan, D. Grady, B. Murphy, G. Qian, R. E. Rosholt, A. D. Ruslanov

Computer Science Technical Reports

No abstract provided.


Tr-2008015: An Efficient Heuristic For The Tree Alignment Problem, Andrés Varón, Ward Wheeler, Amotz Bar-Noy Jan 2008

Tr-2008015: An Efficient Heuristic For The Tree Alignment Problem, Andrés Varón, Ward Wheeler, Amotz Bar-Noy

Computer Science Technical Reports

No abstract provided.


Tr-2008013: Content-Based 3d Mosaics For Large-Scale Dynamic Urban Scenes, Hao Tang, Zhigang Zhu Jan 2008

Tr-2008013: Content-Based 3d Mosaics For Large-Scale Dynamic Urban Scenes, Hao Tang, Zhigang Zhu

Computer Science Technical Reports

No abstract provided.


Tr-2008011: Contrast Transfer Function Correction In Electron Microscopy, Joanna Klukowska Jan 2008

Tr-2008011: Contrast Transfer Function Correction In Electron Microscopy, Joanna Klukowska

Computer Science Technical Reports

No abstract provided.


Tr-2008001: Public And Private Communication Are Different: Results On Relative Expressivity, Bryan Renne Jan 2008

Tr-2008001: Public And Private Communication Are Different: Results On Relative Expressivity, Bryan Renne

Computer Science Technical Reports

No abstract provided.


Tr-2008003: Unified Nearly Optimal Algorithms For Structured Integer Matrices And Polynomials, Victor Y. Pan, Brian Murphy, Rhys E. Rosholt Jan 2008

Tr-2008003: Unified Nearly Optimal Algorithms For Structured Integer Matrices And Polynomials, Victor Y. Pan, Brian Murphy, Rhys E. Rosholt

Computer Science Technical Reports

No abstract provided.


Tr-2008004: Additive Preconditioning For Matrix Computations, Victor Y. Pan, Dmitriy Ivolgin, Brian Murphy, Rhys Eric Rosholt, Yuqing Tang, Xiaodong Yan Jan 2008

Tr-2008004: Additive Preconditioning For Matrix Computations, Victor Y. Pan, Dmitriy Ivolgin, Brian Murphy, Rhys Eric Rosholt, Yuqing Tang, Xiaodong Yan

Computer Science Technical Reports

No abstract provided.


Tr-2008005: Weakly Random Additive Preconditioning For Matrix Computations, Victor Y. Pan, Dmitriy Ivolgin, Brian Murphy, Rhys Eric Rosholt, Yuqing Tang, Xiaodong Yan Jan 2008

Tr-2008005: Weakly Random Additive Preconditioning For Matrix Computations, Victor Y. Pan, Dmitriy Ivolgin, Brian Murphy, Rhys Eric Rosholt, Yuqing Tang, Xiaodong Yan

Computer Science Technical Reports

No abstract provided.


Nicholas Freudenberg: A Selected Bibliography To Accompany A Conversation On Health Law, Julie Graves Krishnaswami Jan 2008

Nicholas Freudenberg: A Selected Bibliography To Accompany A Conversation On Health Law, Julie Graves Krishnaswami

Publications and Research

No abstract provided.


Public School Governance And Democracy: Does Public Participation Matter?, Natalie Gomez-Velez Jan 2008

Public School Governance And Democracy: Does Public Participation Matter?, Natalie Gomez-Velez

Publications and Research

No abstract provided.


Servant Of One's Own: The Continuing Class Struggle In Feminist Legal Theories And Practices, Ruthann Robson Jan 2008

Servant Of One's Own: The Continuing Class Struggle In Feminist Legal Theories And Practices, Ruthann Robson

Publications and Research

No abstract provided.


Traditional Advocacy For Nontraditional Youth: Rethinking Best Interest For The Queer Child, Sarah Valentine Jan 2008

Traditional Advocacy For Nontraditional Youth: Rethinking Best Interest For The Queer Child, Sarah Valentine

Publications and Research

No abstract provided.


Tr-2008006: Additive Preconditioning, Eigenspaces, And The Inverse Iteration, Victor Y. Pan, Xiaodong Yan Jan 2008

Tr-2008006: Additive Preconditioning, Eigenspaces, And The Inverse Iteration, Victor Y. Pan, Xiaodong Yan

Computer Science Technical Reports

No abstract provided.


Tr-2008009: Solving Homogeneous Linear Systems With Weakly Randomized Additive Preprocessing, Victor Y. Pan, Guoliang Qian Jan 2008

Tr-2008009: Solving Homogeneous Linear Systems With Weakly Randomized Additive Preprocessing, Victor Y. Pan, Guoliang Qian

Computer Science Technical Reports

No abstract provided.


Tr-2008010: The Logic Of Justification, Sergei Artemov Jan 2008

Tr-2008010: The Logic Of Justification, Sergei Artemov

Computer Science Technical Reports

No abstract provided.


Tr-2008014: Why Do We Need Justification Logic?, Sergei Artemov Jan 2008

Tr-2008014: Why Do We Need Justification Logic?, Sergei Artemov

Computer Science Technical Reports

No abstract provided.


Our Existential Death Penalty: Judges, Jurors, And Terror Management, Jeffrey Kirchmeier Jan 2008

Our Existential Death Penalty: Judges, Jurors, And Terror Management, Jeffrey Kirchmeier

Publications and Research

No abstract provided.


Justice Sandra Day O’Connor: A Selected Annotated Bibliography, Julie Graves Krishnaswami Jan 2008

Justice Sandra Day O’Connor: A Selected Annotated Bibliography, Julie Graves Krishnaswami

Publications and Research

No abstract provided.


Sitting On A Tinderbox': Racial Conflict, Teacher Discretion And The Centralization Of Disciplinary Authority, Judith R. Kafka Jan 2008

Sitting On A Tinderbox': Racial Conflict, Teacher Discretion And The Centralization Of Disciplinary Authority, Judith R. Kafka

Publications and Research

The centralization of school discipline in the second half of the twentieth century is widely understood to be the inevitable result of court decisions granting students certain civil rights in school. This study examines the process by which school discipline became centralized in the Los Angeles City School District in the late 1960s and early 1970s, however, and finds that the locus of control over student discipline shifted from the school site to the centralized district largely in response to local pressures. Indeed, during a period of large-scale student unrest, and in an environment of widespread racial and cultural tensions, …


Measuring Knowledge Of Natural Selection: A Comparison Of The C.I.N.S., An Open-Response Instrument, And An Oral Interview, Ross Nehm, Irvin Sam Schonfeld Jan 2008

Measuring Knowledge Of Natural Selection: A Comparison Of The C.I.N.S., An Open-Response Instrument, And An Oral Interview, Ross Nehm, Irvin Sam Schonfeld

Publications and Research

Growing recognition of the central importance of fostering an in-depth understanding of natural selection has, surprisingly, failed to stimulate work on the development and rigorous evaluation of instruments that measure knowledge of it. We used three different methodological tools, the Conceptual Inventory of Natural Selection (CINS), a modified version of Bishop and Anderson's (Bishop and Anderson [1990] Journal of Research in Science Teaching 27: 415-427) open-response test that we call the Open Response Instrument (ORI), and an oral interview derived from both instruments, to measure biology majors' understanding of and alternative conceptions about natural selection. We explored how these instruments …


Dominican Women Across Three Generations: Educational Dreams, Goals And Hopes, Rosie M. Soy, Stefan Bosworth Jan 2008

Dominican Women Across Three Generations: Educational Dreams, Goals And Hopes, Rosie M. Soy, Stefan Bosworth

Publications and Research

This study explores the struggle of Dominican women to access formal education and the impact of such access in their lives and on their own perceptions of their experiences. The essay captures the voices of female members of three generations of Dominican immigrant families in New York City.


Graduate Bulletin 2008-2009, John Jay College Of Criminal Justice Jan 2008

Graduate Bulletin 2008-2009, John Jay College Of Criminal Justice

College Bulletins

No abstract provided.


Removing Long-Term Errors From The Avhrr Observation Based On Normalized Difference Vegetation Index (Ndvi), Md Zahidur Rahman, Leonid Roytman, Atiqur Rahman, Felix Kogan, Runa Jesmin Jan 2008

Removing Long-Term Errors From The Avhrr Observation Based On Normalized Difference Vegetation Index (Ndvi), Md Zahidur Rahman, Leonid Roytman, Atiqur Rahman, Felix Kogan, Runa Jesmin

Publications and Research

This paper investigates Normalized Difference Vegetation Index (NDVI) stability in the NOAA/NESDIS Global Vegetation Index (GVI) data during 1982-2003. Advanced Very High Resolution Radiometer (AVHRR) weekly data for the five NOAA afternoon satellites for the China dataset is studied, for it includes a wide variety of different ecosystems represented globally. It was found that data for the years 1988, 1992, 1993, 1994, 1995 and 2000 are not stable enough compared to other years because of satellite orbit drift, and AVHRR sensor degradation. It is assumed that data from NOAA-7 (1982, 1983), NOAA-9 (1985, 1986), NOAA-11 (1989, 1990), NOAA-14 (1996, 1997), …


Advocate, January 2008, Vol. [19], No. [3], Gc Advocate Jan 2008

Advocate, January 2008, Vol. [19], No. [3], Gc Advocate

The Advocate

TABLE OF CONTENTS:

Plan Colombia and the American War on Drugs in Latin America. Michael Busch (p. 1)

Are Hunter’s Graduate Students Paying to Teach? Unpaid Assistantships Spark Controversy on Campus (p. 1)

From the Editor’s Desk: The Rhetoric of Demonization (p. 2)

Graduate Center Technology: Windows Live Email Move on Hold (p. 3)

Dispatches from the Front: In the Classroom of the Critical Mind. Lynne DeSilva-Johnson (p. 4)

Grad Life: Wanted: Wealthy Patron(s) to Fund My Last Year of Dissertation Work. Lindsay Sarah Krasnoff (p. 5)

Adjuncting: The Adjunct Project: Who Are We, What Are We Doing, and How …