Digital Commons Network^™

Drosophila Parasitoids Go To Space: Unexpected Effects Of Spaceflight On Hosts And Their Parasitoids, Jennifer Chou, Johnny R. Ramroop, Amanda M. Saravia-Butler, Brian Wey, Matthew P. Lera, Medaya L. Torres, Mary Ellen Heavner, Janani Iyer, Siddhita D. Mhatre, Sharmila Bhattacharya, Shubha Govind

Publications and Research

While fruit flies (Drosophila melanogaster) and humans exhibit immune system dysfunction in space, studies examining their immune systems’ interactions with natural parasites in space are lacking. Drosophila parasitoid wasps modify blood cell function to suppress host immunity. In this study, naive and parasitized ground and space flies from a tumor-free control and a blood tumor-bearing mutant strain were examined. Inflammation-related genes were activated in space in both fly strains. Whereas control flies did not develop tumors, tumor burden increased in the space-returned tumor-bearing mutants. Surprisingly, control flies were more sensitive to spaceflight than mutant flies; many of their …

Reorganization Of Dopamine Circuitry In The Anterior Corpus Callosum Between Early Adolescence And Adulthood In The Mouse, Megan Caldwell, Josue Criollo Mendoza, Xin Yan Zhu Jiang, Colin Alarcon, Vanessa Ayo-Jibunoh, Shelby Louis, Daniel Maronna, Rania Darwish, Jaquelyn Tomaio, Susana Mingote, Leora Yetnikoff

Advanced Science Research Center

The maturation of forebrain dopamine circuitry occurs over multiple developmental periods, extending from early postnatal life until adulthood, with the precise timing of maturation defined by the target region. We recently demonstrated in the adult mouse brain that axon terminals arising from midbrain dopamine neurons innervate the anterior corpus callosum and that oligodendrocyte lineage cells in this white matter tract express dopamine receptor transcripts. Whether corpus callosal dopamine circuitry undergoes maturational changes between early adolescence and adulthood is unknown but may be relevant to understanding the dramatic micro- and macro-anatomical changes that occur in the corpus callosum of multiple species …

An Accidental Sociologist Learns The Power Of Listening, Jessie Daniels

Publications and Research

A personal essay by a white sociologist describes her experience with becoming a sociologist and unlearning racism through a qualitative research project in which she had to transcribe interviews with middle-class Black Americans.

Be: Fall/Winter 2023–2024 Issue, Be: A Journal Of Black Experimental And Interdisciplinary Work

Publications and Research

Our fall/winter issue explores, with a cool and objective eye, memory and history; it may give you some necessary de ja vu, as we think of family, books, and films we want to preserve. This is our interview/review issue, and we’ve spoken to people or reviewed work that seems necessary for building better futures. Our interview with Amos White argues for the preservation of life-giving and life-affirming trees. We’ve also included reviews of heart-opening books — Tara Christina’s “More than a Drop” and Caron Knauer’s “American Slavery on Film” — that reinforce the significance of familial and collective memory. And …

Information Behavior And Hiv/Aids/Sti Awareness Among Bangladeshi Female Sex Workers: Do Informational Programs Help?, Nafiz Z. Shuva, Radia Taisir, Parvez Sazzad Mallick

Publications and Research

Using de Certeau's concepts of “tactics” and “strategies,” this study explores the everyday information seeking behavior of female sex workers (FSWs) in Bangladesh. This study also examined the effectiveness of informational programs on HIV/AIDS and STI in empowering FSWs to negotiate condom use during sex. A mixed method research design was employed in this study, which included face-to-face surveys with 116 female sex workers (FSWs) and four focus group discussions (FGDs) with 23 street based FSWs. The study finds that Bangladeshi female sex workers use “tactics” in meeting their information needs. They reported rarely using formal information sources such as …

"A Special Cause Of Corrupting Their Youth": The Long History Of Censorship, Hysteria, And The Representation Of Queer Desire In Literature, Kenia Torres

Student Theses and Dissertations

This thesis will focus on queer representation in literature, going all the way back to the works of Milton and Shakespeare and include an exploration of contemporary text Gender Queer by Maia Kobabe. I will trace queer representation back to these authors from the canon to show that queer representation in literature and societies’ hysterical reaction to it are neither new nor emergent. Chapter 1 addresses the trending outrage towards books that include LGBTQ+ representation, framing it as a “new” and “emergent” occurrence. Chapter 2 refutes the claims that LGBTQ+ representation is either of those things by introducing Milton’s angels— …

From Doormats To Three-Dimensions: The Evolution Of Female Characters In Anime’S Action Genre, Sajina Shrestha

Capstones

Strong female characters have always been an outlier and not the trend in the action genre of anime. However, new writers are bringing fleshed-out female characters to the forefront, making for better viewing.

https://docs.google.com/document/d/1p3FROe7uFQNNTR0rwrnwlTlmXzqpvqCvQotshTUZMxs/edit?usp=sharing

Erasing Race, Emily Swanson

Capstones

Since the murder of George Floyd, the Minneapolis Police Department has increasingly lagged in its reporting of race data.

Neurodivergent Artists In Nyc, Brianna R. Poulos

Capstones

Workplaces, classrooms, and creative studios are just a few examples of everyday spaces that are largely designed with neurotypical norms in mind. Creating, sharing, and funding a creative vision is difficult for any artist, but these struggles are amplified for artists with intellectual disabilities who may have been overlooked or not given the same opportunities.

Over the last 18 months, journalist Brianna Rebecca Poulos has worked with neurodivergent artists in New York City and non-profits already working to serve this community of creatives. Brianna created a landing page to help neurodivergent artists in New York City access important information about …

Improving Disability Inclusion Through Professional Development, Carli Spina

Urban Library Journal

Building a shared understanding of the importance of disability inclusion and the concrete steps everyone at the library can take towards this goal, is an important first step towards improving services for disabled patrons and the work environment for disabled employees. Offering training on these specific topics can jumpstart this activity at virtually any library. Guided by existing research in the field, this article offers concrete guidance on creating and offering this training at libraries to improve disability inclusion in the community.

At Noon: (Post)Nihilistic Temporalities In The Age Of Machine-Learning Algorithms That Speak, Talha Issevenler

Publications and Research

This article recapitulates and develops the attempts in the Nietzschean traditions to address and overcome the proliferation of nihilism that Nietzsche predicted to unfold in the next 200 years (WP 2). Nietzsche approached nihilism not merely as a psychology but as a labyrinthic and pervasive historical process whereby the highest values of culture and founding assumptions of philosophical thought prevented the further flourishing of life. Therefore, he thought nihilism had to be encountered and experienced on many, often opposing, fronts to be fully consumed and left behind. Thus, just as Nietzsche captured the subtle reinventions of nihilism in new forms …

The Information Literacy Class As Theatrical Performance: A Qualitative Study Of Academic Librarians’ Understanding Of Their Teacher Identity, Mark Aaron Polger

Publications and Research

This qualitative study examines how academic librarians understand, conceptualize, and describe their teacher identity. The role of the academic librarian has greatly changed due to the advent of information technology. Traditionally, they were generalists, who were responsible for selecting and maintaining library collections. Academic librarian roles have evolved into web developers, information literacy (IL) instructors, emerging technology innovators, marketing and outreach coordinators, open education resources (OER) advocates, and scholarly communication experts. This research investigates the academic librarian as teacher phenomenon, how they describe their professional identity as teachers, the skills, knowledge, and competencies they teach, and their beliefs of how …

The Impact Of International Technology Education Standards On The Development Of A National Curriculum: A Case Study In Korea, Euisuk Sung, Yuhuyn Choi, Ji Suk Kim, Eunsang Lee, Yunjin Lim

Publications and Research

South Korea has mandated technology education as a general education subject since 1954. However, recent educational trends, such as the emergence of computer education; artificial intelligence; Science, Technology, Engineering, and Mathematics (STEM); and K-12 engineering education call for considerable change in Korean technology education. The authors translated and published Standards for Technological and Engineering Literacy (STEL) in Korean to introduce the new standards to Korean educators in response to these challenges. This case study will review the history of Korean technology education from its inception in the 1960s and discuss the potential impacts of STEL on the Korean technology education …

Carolyn Williams Collection, 1983-2012, Allen Thomas, Cynthia Tobar

Finding Aids

Finding aid for the Carolyn Williams collection prepared by Bronx Community College Archives.

The Influence Of Nature On Well-Being During The Covid-19 Pandemic: Views From New England Island Residents, Nicole Kras, Jennifer Keenan

New Community College

Researchers are beginning to explore the impact of the COVID-19 pandemic on island populations, but little is known about the experiences of the residents of Nantucket and Martha’s Vineyard in the Northeast region of the United States. In this study, islanders (N=41) provide insight into how spending time in nature influenced their well-being, especially their mental well-being, during this unprecedented time. For the majority of participants, the influence of nature on their well-being increased during the pandemic. Additionally, participants shared benefits of island living such as isolation from the mainland, as well as challenges such as food and supply shortages. …

Insights Into The Molecular Roles Of Foxr2 In The Pathology Of Primary Pediatric Brain Tumors, Rajendra Gharbaran

Publications and Research

Forkhead box gene R2 (FOXR2) belongs to the family of FOX genes which codes for highly conserved transcription factors (TFs) with critical roles in biological processes ranging from development to organogenesis to metabolic and immune regulation to cellular homeostasis. A number of FOX genes are associated with cancer development and progression and poor prognosis. A growing body of evidence suggests that FOXR2 is an oncogene. Studies suggested important roles for FOXR2 in cancer cell growth, metastasis, and drug resistance. Recent studies showed that FOXR2 is overexpressed by a subset of newly identified entities of embryonal tumors. This review discusses the …

Balanced Blended Space: Proposing A Universal Theoretical Framework For Combinative Reality, David Smith, Frederick Bianchi

Publications and Research

In today's fragmented societies, a unified framework for communication and collaboration across different realities is crucial. We introduce Balanced Blended Space (BBS) as a framework for describing combinative reality, encompassing virtual, physical, and conceptual realms, all intrinsically connected. Interactions within these environments shape our perceptual space. This paper outlines key axiomatic assumptions, criteria for a universal framework, and fundamental terminology. We identify deep symmetries enabling the BBS framework, including Cognitive and Computational Symmetry, Physical and Virtual Symmetry, Mediation Pathway Symmetry, Space-Time Symmetry, and Sensory Symmetry. We propose tests to determine its viability, emphasizing virtual intelligence as a collaborative partner. We …

Proceedings Of The Cuny Games Conference 9.0, Robert O. Duncan, Grace L. Axler-Diperte, Joseph Bisz, Christina Boyle, Devorah Kletenik, Carolyn Stallard

Publications and Research

The CUNY Games Network is an organization dedicated to encouraging research, scholarship and teaching in the developing field of games-based learning. We connect educators from every campus and discipline at CUNY and beyond who are interested in digital and non-digital games, simulations, and other forms of interactive teaching and inquiry-based learning.

Diminazene Aceturate-Induced Cytotoxicity Is Associated With The Deregulation Of Cell Cycle Signaling And Downregulation Of Oncogenes Furin, C-Myc, And Foxm1 In Human Cervical Carcinoma Hela Cells, Rajendra Gharbaran

Publications and Research

Diminazene aceturate (DIZE) is an FDA‐listed small molecule known for thetreatment of African sleeping sickness. In vivo studies showed that DIZE may bebeneficial for a range of human ailments. However, there is very limited informationon the effects of DIZE on human cancer cells. The current study aimed to investigatethe cytotoxic responses of DIZE, using the human carcinoma Hela cell line. WST‐1cell proliferation assay showed that DIZE inhibited the viability of Hela cells in adose‐dependent manner and the observed response was associated with thedownregulation of Ki67 and PCNA cell proliferation markers. DIZE‐treated cellsstained with acridine orange‐ethidium and JC‐10 dye revealed cell …

Antología Vol. Iii Crónica, Cuento, Microrrelato, Poesía Y Relato, Jose Higuera Lopez, Dejanira Alvarez Cardenas

CUNY Mexican Studies Institute

Creada por iniciativa del Instituto de Estudios Mexicanos de CUNY,

la Feria Internacional del Libro de la Ciudad de Nueva York es el espacio

por antonomasia de la promoción del español en la ciudad más

vibrante y cosmopolita de los Estados Unidos. Un español que se

mantiene vivo y cambiante por las muchas migraciones que componen

el entramado de la metrópoli y cuya vitalidad se ve reflejada en

la expresión escrita de la lengua; no solo en el terreno de la literatura

sino también en los de la academia y el periodismo.

La literatura producida en español en la ciudad …

Collect Cosmic Dust, Make It Into Bright Stars: The Use Of Temporal Data In Regeneration Of Life Space And Time Via A Construction Of The Political-Sociological Theory Of Justice, Yi Wang

Dissertations, Theses, and Capstone Projects

This thesis argues for an argument-counterargument approach to the atypical classics of Franz Kafka and Emily Dickinson. This approach to the literature is useful for a construction of the political-sociological theory of justice, which claims that the state of a just world is each individual’s lifetime moving in a dialectic-of-anti-violence-and-non-violence manner.

Wanting Under Surveillance: A Critical Analysis Of Young Women’S Sexual Desire, Jennifer Chmielewski

Dissertations, Theses, and Capstone Projects

The negotiation of sexual desire is argued to be a vital part of the development of women’s sense of agency and well-being. Whereas desire is a concept that is widely used, measured, and diagnosed, women’s experiences of desire are poorly understood. Heeding the calls of feminist psychologists for conceptual analysis, and the need to examine desire within the multiple intimate and sociopolitical contexts in which sexuality develops, my dissertation is a critical feminist analysis of young women’s desire, centered on their subjective and embodied experiences. Moving beyond questions of what women desire or how much desire they have, I explore …

The Confounding Body: Female Corporeality, Androgyny, And Disgust In The Work Of Virginia Woolf And Zinaida Gippius, Yelizaveta Shapiro

Dissertations, Theses, and Capstone Projects

The Confounding Body: Female Corporeality, Androgyny, and Disgust in the Work of Virginia Woolf and Zinaida Gippius examines how the discourses of degeneration, eugenics, and sexology shaped representations of women’s bodies in British and Russian modernist literature. Focusing on the writing of Zinaida Gippius (1869-1945) and Virginia Woolf (1882-1941), I challenge the longstanding argument that both authors attempted to escape the material body by resorting to androgynous tropes. I argue that the material female body takes center stage in both Gippius’s and Woolf’s work and functions as a powerfully paradoxical entity: one that generates disgust and enables oppression while housing …

Expanding The Role Of The Temporal Dimension In Ecological Niche Models: A Study On Mexican Montane Small Mammals, Gonzalo E. Pinilla Buitrago

Dissertations, Theses, and Capstone Projects

Ecological niche models (ENMs) are commonly used to estimate the potential geographic distributions of species and have various uses, such as predicting invasive species' potential distribution, assessing vulnerability to climate change, or estimating paleodistributions. However, ENM developments have primarily focused on solving spatially related issues, underemphasizing the temporal dimensionality of occurrence and environmental data collected over the last century. One limitation of ENMs is the common practice of using recent environmental averages that fail to capture the gradual environmental change over the time span of the occurrence records and can hide trends in environmental variables, a critical piece of information …

Changes In The Epigenetic Landscape Of Oligodendrocyte Progenitor Cells With Time, David K. Dansu

Dissertations, Theses, and Capstone Projects

Most neonatal oligodendrocyte progenitors (nOPCs) give rise to myelinating oligodendrocytes during development, while a proportion are retained as proliferative undifferentiated cells in the adult brain (aOPCs). Previous studies have reported distinct properties for those two populations but the molecular mechanisms underlying these intrinsic differences are not well understood. Using RNA-sequencing and unbiased histone proteomics analysis, we identify transcripts and histone marks that are higher in aOPCs than nOPCs. The genome-wide ChIP-sequencing analysis of chromatin from aOPCs compared to nOPCs detects greater occupancy of the H4K8ac mark at loci corresponding to the higher transcript levels of oligodendrocyte-specific transcription factors and lipid …

Posthuman Lessons For Writing And Well-Being: Reparative Practices, Anna A. Larsson

Dissertations, Theses, and Capstone Projects

The influence of post-humanist interdisciplinary theories on Writing Studies has displaced its conventional preoccupation with the cultivation and management of subjects via First-Year Writing (FYC), to productive but at times artificially divisive ends. This project aims at an inclusive, anti-racist first-year writing ecology through theories of networked consciousness and digital “making.” I reread and recuperate earlier variants of posthumanist writing theory and draw from feminist materialism and mindfulness studies to establish a vision of well-being that I call networked reparative practices. To bring the abstract into the tangible, an often-valued endeavor in a field historically defined by teaching, I introduce …

Out-Of-Distribution Generalization Of Deep Learning To Illuminate Dark Protein Functional Space, Tian Cai

Dissertations, Theses, and Capstone Projects

Dark protein illumination is a fundamental challenge in drug discovery where majority human proteins are understudied, i.e. with only known protein sequence but no known small molecule binder. It's a major road block to enable drug discovery paradigm shift from single-targeted which looks to identify a single target and design drug to regulate the single target to multi-targeted in a Systems Pharmacology perspective. Diseases such as Alzheimer's and Opioid-Use-Disorder plaguing millions of patients call for effective multi-targeted approach involving dark proteins. Using limited protein data to predict dark protein property requires deep learning systems with OOD generalization capacity. Out-of-Distribution (OOD) …

The Archival Impulse: English Family Record Keeping And Archives, Ca. 1450–1700, Maura Kenny

Dissertations, Theses, and Capstone Projects

England in the fifteenth through seventeenth centuries witnessed a proliferation of documents arising from a growth in literacy and an expansion of state administrative offices. Scholarship on the archival history of this period has grown recently but it has focused mainly on institutional and state archives. Very little has been written about family or personal archives and the uses made of them. Based on modern archival theory and extensive archival research, this dissertation seeks to fill this gap by addressing the creation of family records and archives as a whole, exploring early modern English families as a “community of records.” …

A Novel Therapeutic Strategy For Alzheimer’S Disease: Sex-Dependent Mechanisms Altered By The Hdac Inhibitor Rg2833 In A Transgenic Rat Model, Kelechi Ndukwe

Dissertations, Theses, and Capstone Projects

Alzheimer’s disease (AD) is the most common cause of dementia. In the United States, AD affects about 6.2 million Americans and is projected to reach 13.8 million by 2050. Currently, there are no effective therapies for AD and therapies targeting epigenetic mechanisms have shown to be effective in improving cognitive performance in animal models of AD. However, until now no study has reported sex-dependent mechanisms leading to differential expression of genes that contribute to changes in AD pathology. From our in silico studies, we identified an FDA-approved drug, RG2833 (N-[6-(2-aminoanilino)-6-oxohexyl]-4-methylbenzamide) that penetrates the blood brain barrier and can potentially ameliorate …

The Role Of Nuclear Quantum Effects In Supercooled Water And Amorphous Ice, Ali H. Eltareb

Dissertations, Theses, and Capstone Projects

Water is one of the most important substances on Earth and plays a fundamental role in numerous scientific and engineering applications. Interestingly, water behaves much differently than other liquids. For example, water shows an anomalous density maximum at 277 K, the solid phase (ice) is less denser than the liquid, and its thermodynamic response functions, such as the specific heat C_P and isothermal compressibility κ_T, also increase anomalously upon cooling. In the glassy state, water can exist in two different forms, low-density and high-density amorphous ice (LDA and HDA). While water has been scrutinized for many centuries, …