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Comparative Genomics Of The Family Vibrionaceae Reveals The Wide Distribution Of Genes Encoding Virulence-Associated Proteins, Timothy G. Lilburn, Jianying Gu, Hong Cai, Yufeng Wang

Publications and Research

Background Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important role in the emergence of new pathogenic strains within this family. Data from the sequenced genomes of strains in this family could show how the genes encoded by all these strains, known as the pangenome, are distributed. Information about the core, accessory and panproteome of this family can show how, for example, genes encoding virulence-associated proteins are distributed and help us understand how virulence emerges. Results We deduced the …

¡Escriba! ¡Write! Volume 8, June 2010, Hostos Community College Library

¡Escriba!

No abstract provided.

Neural Substrates Of Reliability-Weighted Visual-Tactile Multisensory Integration, Michael S. Beauchamp, Siavash Pasalar, Tony Ro

Publications and Research

As sensory systems deteriorate in aging or disease, the brain must relearn the appropriate weights to assign each modality during multisensory integration. Using blood-oxygen level dependent functional magnetic resonance imaging of human subjects, we tested a model for the neural mechanisms of sensory weighting, termed “weighted connections.” This model holds that the connection weights between early and late areas vary depending on the reliability of the modality, independent of the level of early sensory cortex activity. When subjects detected viewed and felt touches to the hand, a network of brain areas was active, including visual areas in lateral occipital cortex, …

Newborn Infants Learn During Sleep, William P. Fifer, Dana L. Byrd, Michelle Kaku, Inge-Marie Eigsti, Joseph R. Isler, Jillian Grose-Fifer, Amanda R. Tarullo, Peter D. Balsam

Publications and Research

Newborn infants must rapidly adjust their physiology and behavior to the specific demands of the novel postnatal environment. This adaptation depends, at least in part, on the infant’s ability to learn from experiences. We report here that infants exhibit learning even while asleep. Bioelectrical activity from face and scalp electrodes was recorded from neonates during an eye movement conditioning procedure in which a tone was followed by a puff of air to the eye. Sleeping newborns rapidly learned the predictive relationship between the tone and the puff. Additionally, in the latter part of training, these infants exhibited a frontally maximum …

Interactive Kinds, Muhammad Ali Khalidi

Publications and Research

This paper examines the phenomenon of 'interactive kinds' first identified by Ian Hacking. An interactive kind is one that is created or significantly modified once a concept of it has been formulated and acted upon in certain ways. Interactive kinds may also 'loop back' to influence our concepts and classifications. According to Hacking, interactive kinds are found exclusively in the human domain. After providing a general account of interactive kinds and outlining their philosophical significance, I argue that they are not confined to the human realm, but that they can also occur elsewhere. Hence, I conclude by arguing that interactive …

Induction Of Neuro-Protective/Regenerative Genes In Stem Cells Infiltrating Post-Ischemic Brain Tissue, Gokhan Yilmaz, J Steven Alexander, Cigdem Erkuran Yilmaz, D Neil Granger

Publications and Research

Background- Although the therapeutic potential of bone marrow-derived stromal stem cells (BMSC) has been demonstrated in different experimental models of ischemic stroke, it remains unclear how stem cells (SC) induce neuroprotection following stroke. In this study, we describe a novel method for isolating BMSC that infiltrate postischemic brain tissue and use this method to identify the genes that are persistently activated or depressed in BMSC that infiltrate brain tissue following ischemic stroke. Methods- Ischemic strokes were induced in C57BL/6 mice by middle cerebral artery occlusion for 1 h, followed by reperfusion. BMSC were isolated from H-2 Kb-tsA58 (immortomouse™) mice, and …

Estimated Birth Weight And Adult Cardiovascular Risk Factors In A Developing Southern Chinese Population: A Cross Sectional Study, C. Mary Schooling, C. Q. Jiang, T. H. Lam, B. J. Cowling, S. L. Yeung, W. S. Zhang, K. K. Cheng, G. M. Leung

Publications and Research

Background: Birth weight is negatively associated with cardiovascular diseases and diabetes, but the associations are less well-established in developing populations where birth weight is often unavailable. We studied the association of birth weight and cardiovascular risk, using birth rank as an instrumental variable, in Southern China.

Methods: We used published data on birth weight by birth rank from an appropriate population and baseline data from the Guangzhou Biobank Cohort Study phases 2 & 3 (2005-8) to examine the adjusted associations, using instrumental variable analysis, of birth weight with clinically measured cardiovascular risk factors and the metabolic syndrome in older …

Interactions Of Host Proteins With The Murine Leukemia Virus Integrase, Barbara Studamire, Stephen P. Goff

Publications and Research

Retroviral infections cause a variety of cancers in animals and a number of diverse diseases in humans such as leukemia and acquired immune deficiency syndrome. Productive and efficient proviral integration is critical for retroviral function and is the key step in establishing a stable and productive infection, as well as the mechanism by which host genes are activated in leukemogenesis. Host factors are widely anticipated to be involved in all stages of the retroviral life cycle, and the identification of integrase interacting factors has the potential to increase our understanding of mechanisms by which the incoming virus might appropriate cellular …

The Ticker, May 3, 2010

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

Hsp110 Chaperones Control Client Fate Determination In The Hsp70–Hsp90 Chaperone System, Atin K. Mandal, Patrick A. Gibney, Nadinath B. Nillegoda, Maria A. Theodoraki, Avrom J. Caplan, Kevin A. Morano

Publications and Research

The Hsp110 family of protein chaperones was known to promote maturation of Hsp90 client proteins. The yeast Hsp110 ortholog Sse1 is now shown to influence the decision to fold or degrade substrates of the Hsp70–Hsp90 chaperone system when maturation is compromised.

Excitability Changes In The Sciatic Nerve And Triceps Surae Muscle After Spinal Cord Injury In Mice, Zaghloul Ahmed, Robert Freedland, Andrzej Wieraszko

Publications and Research

Background From the onset to the chronic phase of spinal cord injury (SCI), peripheral axons and muscles are subjected to abnormal states of activity. This starts with very intense spasms during the first instant of SCI, through a no activity flaccidity phase, to a chronic hyperactivity phase. It remains unclear how the nature of this sequence may affect the peripheral axons and muscles. Methods We set out to investigate the changes in excitability of the sciatic nerve and to characterize the properties of muscle contractility after contusive injury of the mouse thoracic spinal cord. Results The following changes were observed …

Exercise As An Intervention For The Age-Related Decline In Neural Metabolic Support, Brenda J. Anderson, Shayri J. Greenwood, Daniel Mccloskey

Publications and Research

To identify interventions for brain aging, we must first identify the processes in which we hope to intervene. Brain aging is a period of decreasing functional capacity and increasing vulnerability, which reflect a reduction in morphological organization and perhaps degeneration. Since life is ultimately dependent upon the ability to maintain cellular organization through metabolism, this review explores evidence for a decline in neural metabolic support during aging, which includes a reduction in whole brain cerebral blood flow, and cellular metabolic capacity. Capillary density may also decrease with age, although the results are less clear. Exercise may be a highly effective …

Tyrannobdella Rex N. Gen. N. Sp. And The Evolutionary Origins Of Mucosal Leech Infestations, Anna J. Phillips, Renzo Arauco-Brown, Alejandro Oceguera-Figueroa, Gloria P. Gomez, María Beltrán, Yi-Te Lai, Mark E. Siddall

Publications and Research

Background: Leeches have gained a fearsome reputation by feeding externally on blood, often from human hosts. Orificial hirudiniasis is a condition in which a leech enters a body orifice, most often the nasopharyngeal region, but there are many cases of leeches infesting the eyes, urethra, vagina, or rectum. Several leech species particularly in Africa and Asia are well known for their propensity to afflict humans. Because there has not previously been any data suggesting a close relationship for such geographically disparate species, this unnerving tendency to be invasive has been regarded only as a loathsome oddity and not a unifying …

The Communicator, April 12, 2010, Bronx Community College

The Communicator

The Communicator newspaper published on April 12, 2010.

The Lethal Giant Larvae Tumour Suppressor Mutation Requires Dmyc Oncoprotein To Promote Clonal Malignancy, Francesca Froldi, Marcello Ziosi, Flavio Garoia, Andrea Pession, Nicola A. Grzeschik, Paola Bellosta, Dennis Strand, Helena E. Richardson, Annalisa Pession, Daniela Grifoni

Publications and Research

Background Neoplastic overgrowth depends on the cooperation of several mutations ultimately leading to major rearrangements in cellular behaviour. Precancerous cells are often removed by cell death from normal tissues in the early steps of the tumourigenic process, but the molecules responsible for such a fundamental safeguard process remain in part elusive. With the aim to investigate the molecular crosstalk occurring between precancerous and normal cells in vivo, we took advantage of the clonal analysis methods that are available in Drosophila for studying the phenotypes due to lethal giant larvae (lgl) neoplastic mutation induced in different backgrounds and tissues. Results We …

Touchstone Volume 3.1 (Spring 2010), Hostos Community College

Touchstone

No abstract provided.

From The Classroom To The Concourse: Studying The Grand Concourse To Discover One's Community, Elyse Zucker, William A. Casari

Touchstone

Walt Whitman’s poem, “I Hear America Singing” inspired the 13 murals painted on the walls of the Grand Concourse U.S. post office located across the street from Hostos Community College. Visited last fall by Professor Zucker’s Reading class (English 92) these looming murals helped students more fully appreciate how art enhances the Grand Concourse and, by extension, education illuminates everyday life. The 1860 poem itself celebrates America and its diversity, which 150 year later, still holds relevance for students.

Collaboration In The Design Classroom, Rees E. E. Shad

Touchstone

No abstract provided.

The Communicator, March 12, 2010, Bronx Community College

The Communicator

The Communicator newspaper published on March 12, 2010.

Catalog Addendum Spring 2010, Kingsborough Community College

Course Catalogs

No abstract provided.

John Jay Sentinel Volume 2, No 3, John Jay College Of Criminal Justice

Student Newspapers

No abstract provided.

Dkk1 Mediated Inhibition Of Wnt Signaling In Postnatal Mice Leads To Loss Of Tec Progenitors And Thymic Degeneration, Masako Osada, Logan Jardine, Ruth Misir, Thomas Andl, Sarah E. Millar, Mark Pezzano

Publications and Research

Background Thymic epithelial cell (TEC) microenvironments are essential for the recruitment of T cell precursors from the bone marrow, as well as the subsequent expansion and selection of thymocytes resulting in a mature self-tolerant T cell repertoire. The molecular mechanisms, which control both the initial development and subsequent maintenance of these critical microenvironments, are poorly defined. Wnt signaling has been shown to be important to the development of several epithelial tissues and organs. Regulation of Wnt signaling has also been shown to impact both early thymocyte and thymic epithelial development. However, early blocks in thymic organogenesis or death of the …

A Novel Tcr Transgenic Model Reveals That Negative Selection Involves An Immediate, Bim-Dependent Pathway And A Delayed, Bim-Independent Pathway, Damian Kovalovsky, Mark Pezzano, Benjamin D. Ortiz, Derek B. Sant'angelo

Publications and Research

A complete understanding of negative selection has been elusive due to the rapid apoptosis and clearance of thymocytes in vivo. We report a TCR transgenic model in which expression of the TCR during differentiation occurs only after V(D)J-like recombination. TCR expression from this transgene closely mimics expression of the endogenous TCRα locus allowing for development that is similar to wild type thymocytes. This model allowed us to characterize the phenotypic changes that occurred after TCR-mediated signaling in self-reactive thymocytes prior to their deletion in a highly physiological setting. Self-reactive thymocytes were identified as being immature, activated and CD4loCD8lo. These cells …

Course Catalog 2010-2011, Laguardia Community College

Course Catalogs

No abstract provided.

“They Use It Like Candy”: How The Use Of Psychotropic Drugs On State-Involved Children In The United States Violates International Law, Angela Burton

Publications and Research

No abstract provided.

Deplete Locally, Impact Globally: Environmental History Of Shore-Whaling In Barbados, W.I, Aldemaro Romero Jr., Joel E. Creswell

Publications and Research

No abstract provided.

Folk Concepts, Jay H. Bernstein

Publications and Research

No abstract provided.

The Future Of Natural Selection Knowledge Measurement: A Reply To Anderson Et Al. (2010), Ross Nehm, Irvin Sam Schonfeld

Publications and Research

The development of rich, reliable, and robust measures of the composition, structure, and stability of student thinking about core scientific ideas (such as natural selection) remains a complex challenge facing science educators. In their recent article (Nehm & Schonfeld 2008), the authors explored the strengths, weaknesses, and insights provided by a detailed exploration of three commonly used measures of student thinking about natural selection in a large sample of underrepresented minority students. One of their core findings was that all of the tools they studied--including the CINS--have strengths and weaknesses that must be carefully taken into consideration by those …

Hostos Community College Academic Bulletin 2009-2010, Hostos Community College

College Bulletins

This is the official college catalog for 2009-2010. It contains course descriptions as well as information on degree programs, college resources and services, financial aid, admissions, and the academic calendar.

Down On The Farm: A Photo Essay Of The Indiana Farmer, Elizabeth Schaible

Publications and Research

No abstract provided.