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Water Condensation And Protein Adsorption On Hybrid Superhydrophobic-Hydrophilic Surfaces, Bikash Mondal

Dissertations, Theses, and Capstone Projects

This thesis describes the study of protein adsorption and water condensation on hybrid superhydrophobic-hydrophilic surfaces for various technological applications such as diagnostics, artificial organs and medical devices, water collection, and heat transfer.

In the chapter 1, a general introduction to wetting theories, superhydrophobic surface, and hybrid surfaces is given. In chapter 2, design and fabrication of a hybrid superhydrophobic surface for studying dropwise condensation and heat transfer is discussed. Effect of surface chemistry and wettability on protein adsorption is discussed in the chapter 3. Finally, in chapter 4, the protein adsorption study on hybrid superhydrophobic surfaces made by 3D-printing and …

Deciphering The Role Of Gfi1b Gene Target Rgs18 In Erythro-Megakaryocytic Lineage Divergence, Ananya Sengupta

Dissertations, Theses, and Capstone Projects

The molecular programs that govern the specification of erythroid and megakaryocytic lineages remain incompletely defined. Gene targeting experiments have shown the transcriptional repressor Gfi (Growth factor independence) 1b to be essential for the generation of both erythroid and megakaryocyte cells. Transcriptional repression of Gfi1b target genes is mediated mainly by the cofactors LSD (lysine demethylase) 1 and CoREST/Rcor1 (REST corepressor 1) or other Rcor factors. To understand the mechanism of Gfi1b action, its target genes were identified by chromatin immunoprecipitation (ChIP on Chip) screens. In this study we present the role of Rgs18 (Regulator of G protein signaling 18), a …

The Fictions Of Whiteness: Transatlantic Race Science, Gender, Nationalism, And The Construction Of Race In Nineteenth-Century American Fiction (1823-1867), Philip E. Kadish

Dissertations, Theses, and Capstone Projects

Fictions of Whiteness argues that political beliefs preceded and determined the race science theories which nineteenth century American white novelists applied or invoked in their work, the inverse of the current critical consensus. For issues ranging from Indian removal to slavery and Reconstruction, and utilizing theories from of Condorcet, Buffon, Camper, Louis Agassiz, James Pritchard, Johannes Blumenbach, and George Borrow these authors shifted allegiances to divergent race theories between and within works, applied those theories selectively to white, black, and Indians characters, and applied the same scientific race theories to politically divergent rhetorical ends. By analyzing shifting application of different …

Response And Responsibility: The War Veterans’ Art Center At The Museum Of Modern Art (1944–48), Laurel Humble

Dissertations, Theses, and Capstone Projects

From 1944–48 the Museum of Modern Art, New York (MoMA) offered free art classes to World War II veterans through an experimental educational initiative called the War Veterans’ Art Center. This project was run by Victor D’Amico, who served as the museum’s first Director of Education from 1937–69. Building on an existing institutional ethos of experimentation and civil service, D’Amico and his colleagues explored the role of creative engagement in facilitating the transition from military service to civilian life. As they experimented with new pedagogical approaches, they also worked to articulate and share their innovative methods with other professionals and …

When Human-Leopard Conflict Turns Deadly: A Cross-Country Situational Analysis, Julie S. Viollaz

Dissertations, Theses, and Capstone Projects

Habitat destruction and pollution are two of the main causes for the decline of the planet’s biodiversity. Yet environmentalists are now recognizing that illegal wildlife killings, both poaching and retaliatory killings due to human-wildlife conflict, are perhaps the next major threat. Biologists have researched illegal killings and their effect on species conservation, but few researchers have applied criminological principles of crime reduction to them. This research will explore the situational factors that drive retaliatory leopard killings in parts of South Africa, Kenya, and India. These factors, human and environmental, include local expectations from wildlife, sensitivity to environmental issues, communication between …

Ceasing To Run Underground: 20th-Century Women Writers And Hydro-Logical Thought, Annie M. Cranstoun

Dissertations, Theses, and Capstone Projects

Starting from two central ecopoetic convictions—the constitutive role of environment in human experience (and vice versa), and text’s ability to connect with the world—this dissertation then moves in a different direction from most ecocritical projects. Instead of looking at the ways literary representation flows back into nature in the forms of attitude, praxis, and policy, this study focuses on the earlier part of the loop: the emergence of text from environment, particularly its aquatic parts, via the faculty of the imagination. In its scrutiny of images that spring directly from matter and its faith in the concept of a personal …

Healthy Beginnings: Exploring The Impact Of Parental Stress And Relationship Quality On Birth Outcomes, Anna A. Divney

Dissertations, Theses, and Capstone Projects

This dissertation consists of three studies exploring the effects of maternal and paternal experiences of stress and perceptions of relationship quality on length of gestation and birth weight. The first study assessed the association of parental relationship quality with the baby’s length of gestation and birth weight among 2,072 families in the Fragile Families and Child Wellbeing study. Romantic relationships can be a substantial source of social support as well as stress, and have been shown to influence many health outcomes. Beyond crude relationship characteristics, however, few studies have assessed the association of other dimensions of relationship quality, such as …

The Evolution Of The Viral Rna Sensor Oas1 In Old World Monkeys And Cetartiodactyls, Ian Fish

Dissertations, Theses, and Capstone Projects

Animals produce an array of sensors patrolling the intracellular environment poised to detect and respond to viral infection. The oligoadenylate synthetase family of enzymes comprises a crucial part of this innate immune response, directly signaling endonuclease activity responsible for inhibiting viral replication. Oligoadenylate synthetase 1 plays a vital role in animal susceptibility to pathogens including flaviviruses such as dengue, West Nile, and hepatitis c virus. This thesis includes a population level analysis of OAS1 diversity within macaque and baboon species followed by a broader survey of the gene in nineteen Old World monkeys. My research found that at the species …

Let Fall: Hysteria And The Psychoanalytic Act, Matthew W. Oyer

Dissertations, Theses, and Capstone Projects

This text proposes to examine the contemporary crisis of psychoanalysis by taking seriously feminist critiques of the theory’s phallocentrism, but arguing that the phallus cannot be metaphorically or metonymically replaced by any substitutive term, as most revisionist theories of psychoanalysis have sought to do. Castration is the central psychoanalytic concept, though the theory always seeks to cover it over. In order to develop a psychoanalysis that can confront this castration that is always repressed and yet, in its persistent return, continuously disrupts the continuity of psychoanalytic theory, a detour is proposed, returning to the origins of psychoanalysis and taking hysteria …

An Exploration Of Target Event Encoding In A Predictive Learning Task With Humans: Integrated Or Separable Processing?, Natasha B. Nadler

Dissertations, Theses, and Capstone Projects

A major theme in the study of Pavlovian learning explores how attributes of a predicted event are represented and encoded. In Pavlovian conditioning, the conditioned stimulus (CS) is frequently assumed to associate with one or more of the various attributes of a motivationally significant unconditioned stimulus (US, e.g. it’s hedonic, motivational, and/or sensory features). The present research asks whether humans learn to predict and encode different aspects of motivationally neutral target events, namely, their specific sensory and temporal features in a separable or integrated manner. This question of how target events are encoded has implications for associative and timing models …

Speaking Of Consequences: Contemporary Music For Political Discourse, Elizabeth Adams

Dissertations, Theses, and Capstone Projects

This dissertation reads politically works by Georges Aperghis, Rick Burkhardt, Mark Enslin, and Elizabeth Hoffman. Chapter 1 argues that suspending intelligibility stimulates the audience to imagine alternative meanings and ways the music might go, in an orientation that is politically desirable. Synthesizing theorizations by Herbert Brün, Joseph Dubiel, Shoshana Felman, and Enslin, it catalogues four techniques for suspending intelligibility, and analyses Enslin’s Sonata Quijada. Chapter 2 suggests that we read politically metaphors of agency and power sharing in chamber textures, and translate those metaphors into our social and political lives. It draws on Elisabeth Le Guin’s reading of Boccherini, …

Toward A Kripkean Concept Of Number, Oliver R. Marshall

Dissertations, Theses, and Capstone Projects

Saul Kripke once remarked to me that natural numbers cannot be posits inferred from their indispensability to science, since we’ve always had them. This left me wondering whether numbers are objects of Russellian acquaintance, or accessible by analysis, being implied by known general principles about how to reason correctly, or both. To answer this question, I discuss some recent (and not so recent) work on our concepts of number and of particular numbers, by leading psychologists and philosophers. Special attention is paid to Kripke’s theory that numbers possess structural features of the numerical systems that stand for them, and to …

The Moving Image In Public Art: U.S. And U.K., 1980–Present, Annie Dell'aria

Dissertations, Theses, and Capstone Projects

This dissertation examines the work of artists who use moving images in contemporary public art. Specifically, these works are understood through their interactions with spectators and the practices of media consumption and public interaction these passersby negotiate when they encounter a work of moving image-based public art. To this end, I argue, through an analysis of public art, that screen spectatorship is an inherently situated experience.

The project of this dissertation is two-fold. First, I outline a typology of moving image-based public art by dividing significant practices into three categories—the enchanting spectacle, the ludic interface, and the illumination of place. …

The Effect Of The Long Anchor Duration On Performance In The Temporal Bisection Procedure, Sho Araiba

Dissertations, Theses, and Capstone Projects

The present study investigated the determinants of the location of the bisection point (BP) in the temporal bisection procedure. Interest in the study of temporal perception emerged from the finding of the scalar property such as Weber’s law for time and the ratio rule in behavior under Pavlovian and instrumental conditioning. One method to investigate temporal perception in both non-human animals and humans is the temporal bisection procedure. The primary dependent variable of this procedure is the BP, which has been taken as the subjective midpoint between two durations. The ratio similarity rule (Gibbon, 1981) hypothesizes that the location of …

Can People Successfully Return To Nature?, Nicholas A. Sollogub

Dissertations, Theses, and Capstone Projects

Throughout the course of human history, people have not only survived but thrived through their intimate knowledge of the land that they occupy. This not only includes the ability to procure food and the materials to build a shelter or tools, but it also contains the information that kept them safe from predators and other natural elements that surrounded them. The Industrial Revolution brought about many changes. People began to leave their rural lifestyles and migrate to cities in large numbers. With technologies and urbanization increasing, people became more and more distant from food production activities. Basic necessities, such as …

Autobiographical Poetry To Plays: Taking Memoir To A Theatrical Level, Ryan P. Tofil

Dissertations, Theses, and Capstone Projects

Pulitzer prize winning playwright John Patrick Shanley wrote, “Theatre is a safe place to do the unsafe things that need to be done.” For my Capstone Project, I have compiled my autobiographical poetry, prose, and performance monologues into a theatrical manuscript to be used as the basis for a play. The final Capstone Project is a manuscript of an anticipated theatrical production based on the grieving process surrounding my brother's suicide, as well as an exploration of my sexuality and the relationships I developed during the years surrounding his death.

The Capstone Project’s theatrical manuscript is also accompanied by a …

Interfictional Identities: Transformation And Dissimulation In The Early Modern Period, Yael Nezer Lavender-Smith

Dissertations, Theses, and Capstone Projects

Interfictional Identities develops the concept of interfictional transformations. In these transformations, characters in early modern texts adopt new identities rooted in previous literature. Specifically, Interfictional Identities explores how four early modern moments of interfictional transformation—of Nick Bottom in Shakespeare’s A Midsummer Night’s Dream, of Pyrocles in Sidney’s New Arcadia, of Uriel da Costa in A Specimen of Human Life, and of Don Quixote in Cervantes’ novel—produce both literary and literal hybridity. One wonders why, in these works, writers and playwrights such as Shakespeare, Sidney, Da Costa, and Cervantes favor interfictional transformations over mere allusions to classical literature, …

Neighborhood Matters: The Impact Of Hispanic Ethnic Density On Future Depressive Symptoms 1-Year Following An Acs Event Among Hispanic Patients, Ellen-Ge Denton, Jonathan Shaffer, Carmela Alcantara, Esteban Cadermil

Publications and Research

The Ethnic Density hypothesis posits that living around others from similar ethnic backgrounds reduces the risk of adverse mental health outcomes such as depression. Contrary to this hypothesis, previous work has shown that Hispanic ethnic density is cross-sectionally associated with increased depressive symptom severity among patients hospitalized with an acute coronary syndrome (ACS; myocardial infarction or unstable angina pectoris). To date, no study has examined the prospective association of Hispanic ethnic density on long-term depressive symptom severity following an acute medical event. We prospectively assessed the impact of Hispanic ethnic density on depressive symptoms, 1-year following an ACS event, among …

Neurodevelopmental Defects Associated With Gestational Exposure To Low Levels Of Dbp In Mice, Françoise Sidime

Dissertations, Theses, and Capstone Projects

The etiology of autism is thought to involve the complex interplay among genetic and environmental factors. Patterns of inheritance suggest an epigenetic component to the development of autism. A variety of environmental risk factors are known to induce epigenetic changes in DNA, affecting many genes including those autism-associated genes (AAG). The plasticizer dibutyl phthalate (DBP; CAS 84-74-2) is a developmental and reproductive toxin that causes a broad range of birth defects resulting in neurological impairments.

To date, although the effect of DBP as an endocrine and a reproductive disruptor are established, there are only few studies that address the effects …

Export / Import: The Promotion Of Contemporary Italian Art In The United States, 1935–1969, Raffaele Bedarida

Dissertations, Theses, and Capstone Projects

Export / Import examines the exportation of contemporary Italian art to the United States from 1935 to 1969 and how it refashioned Italian national identity in the process. I do not concentrate on the Italian art scene per se, or on the American reception of Italian shows. Through a transnational perspective, instead, I examine the role of art exhibitions, publications, and critical discourse aimed at American audiences. Inaugurated by the Fascist regime as a form of political propaganda, this form of cultural outreach to the United States continued after WWII as Italian museums, dealers, and critics aimed to vaunt the …

Wandering In Contemporary Literature: A Narrative Theory Of Cognition, Hillel E. Broder

Dissertations, Theses, and Capstone Projects

This study offers a theory of wandering cognition as an animating feature of western literature, in general, and of contemporary literature, in particular. Unlike existing theories of peripatetic bodies and minds in fiction that focus primarily on political critiques, cultural practices, or pleasures of digression, this theory of wandering offers an aesthetic philosophy and ethical critique of representing cognition, memory, and narrative identity that finds affinities in the political, phenomenological, and ethical thought of Walter Benjamin, Emmanuel Levinas, and Giorgio Agamben.

Unlike existing cognitive theories of literature that apply cognitive theory to literary study (or vice versa), this study develops …

Unidentified Verbal Objects: Contemporary French Poetry, Intermedia, And Narrative, Eric Lynch

Dissertations, Theses, and Capstone Projects

This dissertation examines the vital experimental French poetry of the 1980s to the present. Whereas earlier twentieth century poets often shunned common speech, poets today seek instead to appropriate, adapt, and reorganize a wide variety of contemporary discourses. Narrative also reemerges both in hybridized writing fusing prose and verse and in sequences of digressions and anecdotes. Poetic form becomes specific to a given text as poets adapt techniques from other fields, such as the visual arts, and integrate a wide array of media into literary works. In recent pieces, poets such as Emmanuel Hocquard and Olivier Cadiot incorporate new media …

Messenger Rna Transport And Translation Regulated By The 3' Utrs Of Dendritic Mrnas And Abnormal Alternative Splicing Of Neuroligin1 In The Fmr1 Ko Mouse Hippocampus, Tianhui Zhu

Dissertations, Theses, and Capstone Projects

Fragile X Syndrome (FXS) is one of the most commonly inherited mental retardations. It is caused by the loss of functional fragile X mental retardation protein (FMRP). Loss of functional FMRP is the most widespread single-gene cause of autism. The most prominent phenotype of FXS patients is an IQ ranging from 20 to 70. FMRP is an RNA binding protein, widely expressed in almost all tissues and highly expressed in brain. As a RNA binding protein, 85-90 % of FMRP in the brain is associated with polyribosomes. Approximately 4 % of total mRNA is associated with FMRP, which functions in …

Role Of Bec-1/Beclin 1 And Autophagy Genes In C.Elegans Germline Cell Proliferation, Kristina Ames

Dissertations, Theses, and Capstone Projects

Autophagy is an evolutionary conserved process involved in the cellular adaptation to stress and basal levels of autophagy are crucial for cellular metabolism and homeostasis. Cellular recycling by autophagy is characterized by the formation of distinctive double-membrane vesicles (autophagosomes) that engulf unnecessary cytoplasmic components, such as organelles and long-lived proteins. Failure to remove protein aggregates and/or damaged organelles, via autophagy, has been implicated in various medical conditions such as liver disease, neurodegenerative diseases and cancer. Autophagy may suppress or promote cellular proliferation in tumors, depending on the type and metabolic state of the cell, where autophagy is generally believed to …

Effect Of Temporal Onset Of Mechanical Loading On Tendon To Bone Healing, Determined With A Novel In-Vivo Device, Mark E. Stasiak

Dissertations, Theses, and Capstone Projects

Background: Exposure to tensile loading has been shown to maintain tendon/ligament homeostasis, with the tensile modulus of the tissue increasing in response to greater loading frequency, and even decreasing in the absence of load. However after injury or surgical repair the effect of tensile load is controversial, with many studies implicating mechanical loading with impaired healing. It is currently unknown when the tensile loading imparted during rehabilitation exercise, can be safely reintroduced after surgical tendon repair or ligament reconstruction, and at what time point it can most benefit the remodeling process. To investigate the effect of tensile loading protocols on …

The Lived Experience Of Aging Black Women With Diabetes Nurse-Person Relationships, Deidra G. Brown

Dissertations, Theses, and Capstone Projects

The lived experience of the nurse-person relationship may have meaning for Black women with diabetes as they grow older. However, insufficient nursing research has been conducted in this area. This hermeneutic phenomenological study was designed to provide insight into the experiences of older Black women with diabetes as they transition through the aging process and to elucidate their perceptions of the nurse-person relationship. In-depth semi-structured interviews were conducted to explore the lived experience and perceptions of these women, and data was collected for developing a deeper understanding of this phenomenon. The method used to conduct this research was Max van …

Hydrodynamic Loading In Concomitance With Exogenous Cytokine Stimulation Modulates Differentiation Of Bovine Mesenchymal Stem Cells Towards Osteochondral Lineages, Stephen M. Goldman, Gilda A. Barabino

Publications and Research

Background: Mesenchymal stem cells (MSCs) are viewed as a having significant potential for tissue engineering and regenerative medicine therapies. Clinical implementation of MSCs, however, demands that their preparation be stable and reproducible. Given that environmental and bioprocessing parameters such as substrate stiffness, seeding densities, culture medium composition, and mechanical loading can result in undirected differentiation of the MSC population, the objective of this study was to systematically investigate how hydrodynamic loading influences the differentiation of bone marrow-derived mesenchymal stem cells (MSCs) towards the osteochondral lineages both in the presence and absence of exogenous, inductive factors.

Methods: Expanded bovine MSCs were …

Millets From The Margins: Value, Knowledge And The Subaltern Practice Of Biodiversity In Uttarakhand, India, Priya R. Chandrasekaran

Dissertations, Theses, and Capstone Projects

Millets from the Margins: Value, Knowledge and the Subaltern Practice of Biodiversity in Uttarakhand, India analyzes what is at stake for small-scale, predominantly women, farmers as local varieties of rainfed food grains such as finger millet are being newly commodified and valued as a biodiversity resource. With support from a Doctoral Dissertation Improvement Grant from the National Science Foundation, I conducted seventeen months of ethnographic research with farmers, activists, scientists, NGO leaders, government officials, transnational functionaries and agribusiness representatives in segregated yet interconnected realms ranging from a village in the Himalayan foothills to transnational institutions in Rome.

This work demonstrates …

Status Signaling And The Characterization Of A Chirp-Like Signal In The Weakly Electric Fish Steatogenys Elegans, Caitlin E. Field

Dissertations, Theses, and Capstone Projects

Sensory systems are critical to both exploratory and communicatory processes, the study of which is critical to our understanding of how animals perceive and respond to their environments. In weakly electric fishes the electrosensory system is utilized for both of these purposes. One type of communication, status signaling, is widespread across taxa and frequently hormonally modulated. This hormonal modulation keeps the signal honest, wherein the status of the sender and the production of the status signal itself are both hormone dependent. We investigated exploratory and communicatory strategies of the electromotor system in pulse-type gymnotiforms, with a focus on status communication …

Animal Performance In Big-Time Vaudeville, Catherine M. Young

Dissertations, Theses, and Capstone Projects

Animal vaudevillians have been neglected by academic accounts of vaudeville. Drawing on the rapidly proliferating and highly interdisciplinary field of animal studies, this dissertation combines archival research and cultural theory to fill an important gap in our understanding of how animal bodies and images circulated during the vaudeville era. Taking up Nicole Shukin’s notion of animal capital as both animal “signs and substances” circulating in cultures of capital, I argue that vaudeville animal acts theatricalized animal capital for US citizen-consumers and often circulated animalized capital via racist ideologies and performance modes.

Theatre bookers balanced their reliance on animal acts …