Digital Commons Network^™

Theatres Of Reality, Fiction, And Temporality: Vegard Vinge And Ida Müller’S Ibsen-Saga (2006 - 2015), Andrew L. Friedman

Dissertations, Theses, and Capstone Projects

This dissertation examines the influence of modernist aesthetics and ideologies on contemporary, European and U.S. experimental theatre. I argue that modernist and contemporary experimental theatres offer competing notions of reality, fiction, and temporality, which I interrogate through Vegard Vinge and Ida Müller’s Ibsen-Saga. I illuminate this tension by reading current modes of performance against the Saga’s productions and work practices, as well as their aesthetic and ideological foundation in three modernist sources: the artificiality of Ibsen’s realism, the utopianism and totality of Richard Wagner’s Gesamtkunstwerk, and the temporal provocations of the historical avant-gardes. I contend that the …

Effect Of Cntf Derived Peptide, P021 On Cognition And Pathology In 3xtg-Ad Mouse Model Of Alzheimer's Disease, Narjes Baazaoui

Dissertations, Theses, and Capstone Projects

Studies described in this thesis deal with the preventive effects of a neurogenic/neurotropic peptidergic compound, P021, on neurogenesis and synaptic deficits, neurodegeneration, cognitive impairment, and Ab and tau pathologies in a 3xTg-AD mouse model of Alzheimer’s disease (AD).

Background: AD is a chronic progressive neurodegenerative disease. Its multifactorial nature and the heterogeneity make its treatment especially challenging. Although it is a major burden in society, at present there is no drug that can stop or slow down the progression of the disease. Currently, the only available treatments are symptomatic and for mild to severe stages. The development of a drug …

A Systematic Review Of Dual-Sensory Impairment In Older Adults, Abby F. Malawer

Dissertations, Theses, and Capstone Projects

The elderly population (ages 65 years and older) in the United States is estimated to double between 2000 and 2030 to approximately 72 million people. Among this population, sensory impairment is a chronic disability. The combination of both hearing and vision impairment, referred to as dual-sensory impairment (DSI) is a chronic condition on the rise. The prevalence of DSI ranges from a low of 1.6% to as high as 22.5% depending on the population (Appollonio et al., 1995). Higher prevalence rates tend to emerge in populations receiving rehabilitative and hospital care. DSI impacts independent physical function and verbal communication, along …

Breaking Cover: Confronting Crisis And Displacement In Timbuktu, Mali, Andrew Hernann

Dissertations, Theses, and Capstone Projects

In Spring 2012, a loose alliance of ethnic Tuareg nationalist and Jihadi-Salafist militant groups occupied Mali’s northern regions, forcibly displacing nearly 300,000 residents and ultimately imposing their harsh interpretation of shari’a among those who remained. Later, in January 2013, as these groups began marching towards southern Mali, the French army suddenly intervened, “liberating” urban centers in the North as the militants fled into the Sahara Desert and across the Algerian border. My research examines this period of occupation, displacement and intervention, which most Malians have come to term “the crisis.” Specifically, I analyze the cultural and religious frameworks through which …

Tradition And Transition: American Orthodox Jewish Women Preparing And Becoming Sexually Active Within Marriage, Shoshannah D. Frydman

Dissertations, Theses, and Capstone Projects

The purpose of this project is to expand knowledge about the lived experience of married Orthodox Jewish women’s preparation and transition into sexual activity in marriage. When Orthodox women get married, they are undergoing a significant shift, for many, this is their first experience having a sexual relationship. In addition to the prohibition of premarital sexual behavior, the Orthodox Jewish community has a number of rituals, laws, and practices specifically related to menstruation and sexual relations within marriage. These laws, taharat hamishpacha, or family purity, are a set of laws and practices that regulate sex within marriage for both …

Modulating The Semantic System: The Role Of Bilateral Anterior Temporal Lobes In Confrontation Naming- A Combined Tdcs And Eye-Tracking Study, Sameer Ashaie

Dissertations, Theses, and Capstone Projects

Confrontation naming is a complex process that involves multiple stages and can be initiated through multiple modalities. Models of confrontation naming have implicated areas such as the anterior temporal lobe (ATL) and temporo-parietal junction (TPJ) for the semantic stage of naming. Transcranial direct current stimulation (tDCS) was used to modulate neural excitability in the bilateral ATLs and the TPJs to understand brain-behavior relationships involved in the semantic stage of confrontation naming. Effects of tDCS are often very small or non-existent when measured by reaction times and accuracy. Therefore the present study used more sensitive eye-tracking measures (first fixation duration and …

Christ The Queer: Gender And Sexuality In Scorsese's "The Last Temptation Of Christ", Stephen Barnett

Dissertations, Theses, and Capstone Projects

Although great strides have been made since the landmark 1969 Stonewall Riots in liberating queer equal rights, both politically and societally, there are still prevalent belief systems in strong opposition to those human rights of gender and sexuality. Biblical religion, through its various monotheistic faiths and denominations, continues to condemn queer as a sin against God because, they argue, God, (through the text of the Bible written solely by men), defines queer as an abomination. Yet, the Book of Genesis queers human gender and sexuality through its narrative of Adam and Eve in the Garden of Eden. Nevertheless, the first …

Life Experience: Freddy Got Fingered As Neo-Surrealist Masterpiece, Frank Koshel

Dissertations, Theses, and Capstone Projects

The late Roger Ebert was known for his entertainingly harsh reviews. The review he wrote of the 2001 film Freddy Got Fingered is one notable example. "The day may come when 'Freddy Got Fingered' is seen as a milestone of neo-surrealism. The day may never come when it is seen as funny," wrote Ebert in his April 20, 2001 review of the film. Humor is subjective and there is no accounting for taste but this thesis will prove that the much-maligned film Freddy Got Fingered is a milestone of neo-surrealism. Freddy Got Fingered director Tom Green has a …

Saving Animals: Everyday Practices Of Care And Rescue In The Us Animal Sanctuary Movement, Elan L. Abrell

Dissertations, Theses, and Capstone Projects

This multi-sited ethnography of the US animal sanctuary movement is based on 24 months of research at a range of animal rescue facilities, including a companion animal shelter in Texas, exotic animal sanctuaries in Florida and Hawaii, and a farm animal sanctuary in New York. In the last three decades, animal welfare activists have established hundreds of sanctuaries across the United States in an attempt to save tens of thousands of animals from factory farms, roadside zoos, and other sites of contested animal treatment. These facilities function as laboratories where activists conceive and operationalize new models for ethical relationships with …

On The Syntax/Semantics Of Korean Nominal Particles, Han-Byul Chung

Dissertations, Theses, and Capstone Projects

In this dissertation, I investigate the structural positions of i/ka-marked DPs and un/nun-marked DPs in the light of Kratzer (1988; 1995) and Diesing (1990; 1992). In Korean, unlike German (and English in part), vP-external subjects and vP-internal subjects are not distinguishable at the surface. However, by adopting Kratzer (1988; 1995) and Diesing (1990; 1992), we are able to distinguish between vP-external DPs and vP-internal DPs in Korean.

According to Kratzer and Diesing, syntactic position of a DP has affect in the interpretation of the DP itself, as well as the interpretation of the sentence …

Queering By Example: Sex Education In The Age Of Vlogging, Zoe M. Simpson

Dissertations, Theses, and Capstone Projects

The 1990s saw the rise of third wave feminism, queer theory and the digital age. This paper looks at how the three come together in YouTube video bloggers’ promotion of queer sex-positive ideology. Sex positivism is the belief that all safe, consensual sex is healthy, while queer theory emphasizes the diversity and instability of sex and gender identities. YouTube vloggers engaged in life-streaming profit from the entertainment value of revealing personal sexual information while framing their sexual revelations as healthy, shame-free sex positivism. In doing so, they also put their unique and sometimes changing sexualities on public display, in effect …

Neighborhood And Community Change In Brooklyn's Sunset Park, Anthony G. Aggimenti

Dissertations, Theses, and Capstone Projects

Significant demographic changes within New York City’s neighborhoods have served as an impetus for civil strife, community activism, and political debate. While much attention has been dedicated toward the gentrification occurring in Harlem or Williamsburg, emerging trends indicate that the Brooklyn waterfront neighborhood of Sunset Park is also undergoing a shift. Drawing upon the theoretical frameworks of human ecology, the urban growth machine, and gentrification, the paper posits that Sunset Park is a neighborhood in transition. A three pronged quantitative, historical, and qualitative analysis examines major demographic changes in Sunset Park including the increase in Chinese and Mexican ethnic immigrant …

Kongo To Kings County, Marcus Alan Watson

Dissertations, Theses, and Capstone Projects

This dissertation aims to provide evidence to support the hypothesis that the artifact assemblage found in 1998 under the garret room floor in the attic of the Lott Farmstead is an extension of Kongo-descended cultural practices. This connection is shown by the presence of several artifacts that taken together, invoke a Kongo Cosmogram called the diKenga, alongside artifacts arranged in what is believed to be a Kongo N’Kisi, or spiritual container, that also originates in Kongo ideology. The ceramic found in the kitchen house with an incised X indicates a reverence to this diKenga symbol. Similar symbols have been found …

Hearing Aid Use And Cognitive Function: A Systematic Review, Hershel Korngut

Dissertations, Theses, and Capstone Projects

This systematic review analyzed the research relating the use of hearing aids to cognitive function. Hearing aid use was examined to see if wearing hearing aids improves cognitive function, if the length of time hearing aids are worn impacts cognitive ability, if the type of hearing aid used has any impact on cognitive function, and if hearing aid use slows down cognitive decline. Ten studies met the criteria for this review. An analysis of the research revealed some evidence to support wearing hearing aids improves cognitive function, however, there is substantial evidence that shows no impact between wearing hearing aids …

Mechanisms Of Immune Activation And Suppression By Parasitic Wasps Of Drosophila, Johnny R. Ramroop

Dissertations, Theses, and Capstone Projects

Drosophila melanogaster has served as an excellent model organism to study the molecular processes of innate immunity. Flies essentially lack adaptive immunity and the innate immune system is often divided into the humoral and cellular responses (Lemaitre and Hoffmann 2007). The humoral arm involves the production of antimicrobial peptides, secreted from the fat body, to combat bacterial and fungal infections. The cellular response involves the production of hemocytes (blood cells: crystal cells, plasmatocytes, and lamellocytes) in the larval lymph gland, in the sessile pools, and in circulation (Gold and Bruckner 2014). Microbial pathogens are phagocytosed by plasmatocytes whereas larger parasites …

Provisional Capital: National And Urban Identity In The Architecture And Planning Of Bonn, 1949-1979, Samuel L. Sadow

Dissertations, Theses, and Capstone Projects

This dissertation explores the physical transformation of Bonn in the postwar period, with a particular focus on the 1960s and 1970s, as the city accommodated the West German federal government. Bonn’s long campaign in the 1960s to redraw its municipal borders and the federal government’s construction of several high-rises in the city and its neighbor, Bad Godesberg, were the most concrete markers of Bonn’s evolution as a capital city in this period. The complex political processes and sometimes bitter conflicts behind each of these developments paralleled the gradual and successful entrenchment of democracy in the Federal Republic of Germany. At …

Becoming Serpent: Mapping Coils Of Paranoia In A Neocolonial Security State, Rachel J. Liebert

Dissertations, Theses, and Capstone Projects

What follows is a feminist, decolonial experiment to map the un/settling circulation of paranoia – how it is done, what it does, what it could do – within contemporary conditions of US white supremacy. Drawing on participant observation, interviewing, scientific artifacts, reflexive journaling, and a public art project, I enter white supremacy through a burgeoning form of pre-emptive psy to capture ‘the prodrome’ – a stage-cum-population-cum-figure at the center of a transnational program of research to identify and intervene on ‘pre-psychosis’. I argue that this nascent, contested, and accelerating movement is enacting a contemporary transition from …

Mccarthyism And The Id: "Forbidden Planet" (1956) As A Veiled Criticism Of Mccarthyism In 1950s America, William Lorenzo

Dissertations, Theses, and Capstone Projects

Many American science fiction films of the 1950s served as political allegories commenting on the post-war fears of the nation. One major fear was the fear of communist infiltration: the Red Scare. In films of this era, the enemy walks as one of us. In most of these films, the alien other, the monster from without, takes on a familiar form. But at the height of all these fears comes the fear of the enemy from within, an enemy that winds up destroying us from the inside out, as can be seen in Forbidden Planet (1956). In this film, a …

Data-Driven Synthesis And Evaluation Of Syntactic Facial Expressions In American Sign Language Animation, Hernisa Kacorri

Dissertations, Theses, and Capstone Projects

Technology to automatically synthesize linguistically accurate and natural-looking animations of American Sign Language (ASL) would make it easier to add ASL content to websites and media, thereby increasing information accessibility for many people who are deaf and have low English literacy skills. State-of-art sign language animation tools focus mostly on accuracy of manual signs rather than on the facial expressions. We are investigating the synthesis of syntactic ASL facial expressions, which are grammatically required and essential to the meaning of sentences. In this thesis, we propose to: (1) explore the methodological aspects of evaluating sign language animations with facial expressions, …

Saving: Stem Cell Science, Christian Adoption, And Frozen Embryo Potential In The United States, Risa Cromer

Dissertations, Theses, and Capstone Projects

This dissertation examines the controversial fates of frozen human embryos left over from in vitro fertilization procedures and frozen for future in the United States at the turn of the twenty-first century. Stem cell researchers covet human embryos as wellsprings of biovalue for curing human diseases and generating new forms of wealth. At the same time, pro-life Christians target excess embryos for rescue as adoptable orphans and mobilize the frozen unborn within legal strategies to redefine personhood. As a comparative ethnography, this dissertation reveals what these putatively opposing solutions share in common by examining why and how frozen reproductive remainders …

Traditional Chinese Medicine: A Survey To Assess Inclusion In Dpt Curricula In The United States, Michael Erickson, Paul Nasri, David Perrotto

Dissertations, Theses, and Capstone Projects

The objective of this study is to assess the current level of inclusion of Traditional Chinese Medicine (TCM) in Doctor of Physical Therapy curricula in the United States. This survey provides self-reported data regarding the challenges associated with incorporating TCM into the curriculum. All 228 CAPTE (Commission on Accreditation in Physical Therapy Education) accredited Doctor of Physical Therapy (DPT) programs were included in this survey instrument. A College of Staten Island (CSI) Human & Animal Protection Office (HARPPO) approved survey was e-mailed to the chairperson of each DPT program and respondent data was stored via a secure Survey Monkey® online …

"Follow The Bodies": (Re)Materializing Difference In The Era Of Neoliberal Multiculturalism, Briana Grace Brickley

Dissertations, Theses, and Capstone Projects

This dissertation examines a transnational literary archive in addition to analyzing shifting U.S. American cultural and political landscapes, and shows how critically attending to the various terms, figures, and valences of corporeality opens generative avenues for addressing the contemporary historical conjuncture, often referred to as the neoliberal capitalist era. Neoliberal capitalism, understood here to be a complex, diffuse ideology that manifests in part as a number of broadsweeping economic changes—including widespread deregulation and privatization, the increasing influence of international financial organizations, governmental cuts in social spending, and structural adjustment programs for the formerly colonized nations of the global south—operates in …

Biosynthesis And Roles Of Virulence Conferring Cell Wall Associated Dimycocerosate Esters In Mycobacterium Marinum, Poornima Mohandas

Dissertations, Theses, and Capstone Projects

Mycobacterial species include a variety of obligate and opportunistic pathogens that cause several important diseases affecting mankind such as tuberculosis and leprosy. The most unique feature of these bacteria is their intricate cell wall that poses a permeability barrier to antibiotics and contributes to their pathogenicity and persistence within the host. The cell wall hosts several complex lipids such as dimycocerosate esters (DIMs), which are found in many clinically relevant pathogenic species of mycobacteria. DIMs have been implicated in the virulence of mycobacteria and play a major role in helping the bacteria evade host immune responses. It is therefore crucial …

Circular Oligodeoxynucleotides (Coligos) As Chemically Synthesized, Promoter-Independent Small Rna Expression Vectors, Lodoe Lama

Dissertations, Theses, and Capstone Projects

Small RNAs (sRNA) such as microRNA (miRNA), small interfering RNA (siRNA), and other types of RNA have been found to play many important biological roles in regulation of different cellular process leading to their possible use as therapeutics. However, one of the biggest hurdles in exploiting these sRNAs in therapeutics has been the difficulty in delivering them safely and stably into human tissues. Many delivery approaches have been undertaken to deliver these sRNA, albeit with many shortcomings in terms of cost, stability, and side effects, necessitating the need for alternative approaches. We are exploring an entirely different approach for conveying …

Claiming Time: Thomas Hobbes, John Locke, And Adam Smith On Freedom And Futurity, Jennifer Corby

Dissertations, Theses, and Capstone Projects

This dissertation engages the philosophy of Thomas Hobbes, John Locke, and Adam Smith through the lens of time. By first analyzing their earlier works on the nature of self-consciousness, it demonstrates that each offers a theory of subjectivity that, despite important differences, shares a singular point of distinction from those that typified early modern thought. Against the predominant view that human freedom necessitates immaterial agency, each theorizes a materialist agent that is able to overcome the determinism of the material world by way of the temporal nature of subjectivity. Each understands self-consciousness to be constituted by an extension of memory …

Mechanism Of Action And Applications Of Interleukin 24 In Immunotherapy, Leah Persaud, Dayenny De Jesus, Oliver Brannigan, Maria Richiez-Paredes, Jeannette Huaman, Giselle Alvarado, Linda Riker, Gissete Mendez, Jordan Dejoie, Moira Sauane

Publications and Research

Interleukin 24 (IL-24) is an important pleiotropic immunoregulatory cytokine, whose gene is located in human chromosome 1q32-33. IL-24’s signaling pathways have diverse biological functions related to cell differentiation, proliferation, development, apoptosis, and inflammation, placing it at the center of an active area of research. IL-24 is well known for its apoptotic effect in cancer cells while having no such effect on normal cells. IL-24 can also be secreted by both immune and non-immune cells. Downstream effects of IL-24, after binding to the IL-20 receptor, can occur dependently or independently of the JAK/STAT signal transduction pathway, which is classically involved in …

The Relationship Between Lexical Performance And Regional Gray Matter Volumes: A Longitudinal Study Of Cognitively Healthy Elderly, Jungmoon Hyun

Dissertations, Theses, and Capstone Projects

This study investigated the longitudinal relationship among aging, performance on lexical tasks, and regional gray matter volumes over 2-7 years. A total of 137 older participants who remained cognitively normal were administered four lexical tasks at each time point: the Boston Naming Test (BNT), Vocabulary Test, Semantic- and Phonemic-Fluency task. In addition, they underwent repeated magnetic resonance imaging (MRI) scanning acquired within two months of the lexical tasks. The average interval between time points was 2.36 years (range 1.50-7.64) and the average number of time points was 2.65 times (range 2-5).

Results indicated that age differentially affects lexical task performance …

Animate Impossibilities: On Asian Americanist Critique, Racialization, And The Humanities, Frances H. Tran

Dissertations, Theses, and Capstone Projects

This dissertation works from and through the field of Asian American studies, drawing on Asian Americanist cultural critique and minority discourse, to investigate the relationship among race, the politics of knowledge, and the epistemic function of the humanities. Proliferating discourses on “post-race” and “colorblindness” characterizing the present moment posit a progressive movement beyond racial division, towards recognizing and incorporating minority difference into the academy. However, even as issues like “diversity” have gained visibility as institutional objectives, I contend that this heightened visibility occludes the structural conditions that allow racialization to persist. In this project, I follow the work of thinkers …

Mir-1207-3p Is A Novel Prognostic Biomarker Of Prostate Cancer, Dibash K. Das, Joseph R. Osborne, Hui-Yi Lin, Jong Y. Park, Olorunseun O. Ogunwobi

Publications and Research

MicroRNAs (miRNAs) have been found to be dysregulated in prostate cancer (PCa). In this study, we investigated if miR-1207-3p is capable of distinguishing between indolent and aggressive PCa and if it contributes to explaining the disproportionate aggressiveness of PCa in men of African ancestry (moAA). A total of 404 patients with primary adenocarcinoma of the prostate were recruited between 1988 and 2003 at the Moffitt Cancer Center, Tampa, FL, USA. Patient clinicopathological features and demographic characteristics such as race were identified. RNA samples from 404 postprostatectomy prostate tumor tissue samples were analyzed by real-time quantitative reverse transcription polymerase chain reaction …

Rogues In The Postcolony: The New Picaresque And The Making Of Modern India, Stacey Balkan

Dissertations, Theses, and Capstone Projects

Rogues in the Postcolony looks at Indian picaresque novels that respond to and productively complicate dominant historical narratives by adapting formal conventions of the picaresque novel and by foregrounding the experiences of historically obscured figures, or “rogues.” The project is structured in such a way as to read colonial and postcolonial India through the lens of marginalized persons such as poppy farmers and, more recently, the citizens of Bhopal who continue to struggle with the toxic legacy of the Union Carbide fertilizer factory in their city. I argue that the unreliable narration and non-teleological structure of the picaresque form parody …