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From Half-Free To Property: The Evolution Of Slavery In Dutch New Netherland And English New York, 1621-1712, Sarah E. Hendrickson

Theses and Dissertations

Between 1621 and 1712, Dutch and English colonists imported African slaves to present-day New York to help create a profitable colony. This thesis explores why the Dutch created a society with slavery and how the English transformed New York into a slave society during this period.

Changes In Histone H3 Acetylation On Lysine 9 Accompany Aβ 1-40 Overexpression In An Alzheimer’S Disease Yeast Model, Muna M. Hugais, Samantha N. Cobos, Seth A. Bennett, Jailene Paredes, Genevieve Foran, Mariana P. Torrente

Publications and Research

Alzheimer’s Disease (AD), the most common type of dementia, is a neurodegenerative disease characterized by plaques of amyloid-beta (Aβ) peptides found in the cerebral cortex of the brain. The pathological mechanism by which Aβ aggregation leads to neurodegeneration remains unknown. Interestingly, genetic mutations do not explain most AD cases suggesting that other mechanisms are at play. Epigenetic mechanisms, such as histone post-translational modifications (PTMs), may provide insight into the development of AD. Here, we exploit a yeast Aβ overexpression model to map out the histone PTM landscape associated with AD. We find a modest decrease in the acetylation levels on …

Late Pleistocene And Early Holocene Sea-Level History And Glacial Retreat Interpreted From Shell-Bearing Marine Deposits Of Southeastern Alaska, Usa, James F. Baichtal, Alia J. Lesnek, Risa J. Carlson, Nicholas S. Schmuck, Jane L. Smith, Dennis J. Landwehr, Jason P. Briner

Publications and Research

We leverage a data set of >720 shell-bearing marine deposits throughout southeastern Alaska (USA) to develop updated relative sea-level curves that span the past ~14,000 yr. This data set includes site location, elevation, description when avail-able, and 436 14C ages, 45 of which are published here for the first time. Our sea-level curves suggest a peripheral forebulge developed west of the retreating Cordilleran Ice Sheet (CIS) margin between ca. 17,000 and 10,800 calibrated yr B.P. By 14,870 ± 630 to 12,820 ± 340 cal. yr B.P., CIS mar-gins had retreated from all of southeastern Alaska’s fjords, channels, and passages. At …

We Are Each Other’S Breath: Tracing Interdependency Through Critical Poetic Inquiry, Karen Zaino, Jordan Bell

Publications and Research

In this paper, we utilize poetic methods that seek to surface, but not overdetermine, the unanticipated relational excess produced through literacy practices. Karen, a queer white woman, and Jordan, a cis-gendered heterosexual Black man, wrote a series of letters to one another throughout the Spring 2020 semester. We turned to critical poetic inquiry to analyze the letters, interested in poetry’s capacity to highlight literacy’s critical power and its emergent potential. We found ourselves implicated in each other’s lives in new ways; we found our relationship both strengthened and tested. Such relational indeterminacy creates methodological challenges in literacy research. We found …

Teaching Artificial Intelligence In Technology And Engineering Education, Euisuk Sung

Publications and Research

No abstract provided.

Cryo-Em Structure Of Mechanosensitive Channel Ynai Using Sma2000: Challenges And Opportunities, Claudio Catalano, Danya Ben-Hail, Weihua Qiu, Paul Blount, Amedee Des Georges, Youzhong Guo

Publications and Research

Mechanosensitive channels respond to mechanical forces exerted on the cell membrane and play vital roles in regulating the chemical equilibrium within cells and their environment. Highresolution structural information is required to understand the gating mechanisms of mechanosensitive channels. Protein-lipid interactions are essential for the structural and functional integrity of mechanosensitive channels, but detergents cannot maintain the crucial native lipid environment for purified mechanosensitive channels. Recently, detergent-free systems have emerged as alternatives for membrane protein structural biology. This report shows that while membrane-active polymer, SMA2000, could retain some native cell membrane lipids on the transmembrane domain of the mechanosensitive-like YnaI channel, …

Dietary Diversity And Nutrient Intake Of Han And Dongxiang Smallholder Farmers In Poverty Areas Of Northwest China, Zhuo Wang, Youhai Chen, Shihua Tang, Siqi Chen, Shaoqing Gong, Xinyin Jiang, Liang Wang, Ying Zhang

Publications and Research

This study aimed to evaluate the status of dietary diversity and nutrient intake among Han and Dongxiang smallholder farmers in poor rural areas of northwest China. In this cross-sectional study, dietary intake was assessed in 499 smallholder farmers aged 18–75 years from two nationally designated impoverished counties in Gansu Province, China, using three consecutive 24 h dietary recalls. The dietary diversity score (DDS) and nutrient adequacy ratio (NAR) were adopted to assess dietary diversity and micronutrient adequacy, respectively. The mean DDS (range from 1 to 9) in participants was relatively low (3.81 ± 1.01). Consumption of grains was excessive, while …

Dataset Of Concurrent Eeg, Ecg, And Behavior With Multiple Doses Of Transcranial Electrical Stimulation, Nigel Gebodh, Zeinab Esmaeilpour, Abhishek Datta, Marom Bikson

Publications and Research

We present a dataset combining human-participant high-density electroencephalography (EEG) with physiological and continuous behavioral metrics during transcranial electrical stimulation (tES). Data include within participant application of nine High-Definition tES (HD-tES) types, targeting three cortical regions (frontal, motor, parietal) with three stimulation waveforms (DC, 5 Hz, 30 Hz); more than 783 total stimulation trials over 62 sessions with EEG, physiological (ECG, EOG), and continuous behavioral vigilance/alertness metrics. Experiment 1 and 2 consisted of participants performing a continuous vigilance/alertness task over three 70-minute and two 70.5-minute sessions, respectively. Demographic data were collected, as well as self-reported wellness questionnaires before and after each …

Crossing The Great Divide: Bridging The Researcher–Practitioner Gap To Maximize The Utility Of Remote Sensing For Invasive Species Monitoring And Management, Kelsey Parker, Arthur Elmes, Peter Boucher, Richard A. Hallett, John E. Thompson, Zachary Simek, Justin Bowers, Andrew B. Reinmann

Advanced Science Research Center

Invasive species are increasingly present in our ecosystems and pose a threat to the health of forest ecosystems. Practitioners are tasked with locating these invasive species and finding ways to mitigate their spread and impacts, often through costly field surveys. Meanwhile, researchers are developing remote sensing products to detect the changes in vegetation health and structure that are caused by invasive species, which could aid in early detection and monitoring efforts. Although both groups are working towards similar goals and field data are essential for validating RS products, these groups often work independently. In this paper, we, a group of …

Communication During A Crisis: Keeping Our Patrons Informed During The Covid-19 Pandemic, John P. Delooper, Michelle Ehrenpreis

Urban Library Journal

This article discusses the Leonard Lief Library’s communications strategy to keep its patrons informed during the COVID-19 crisis. The Leonard Lief Library at Lehman College (CUNY) made use of its website, social media, and research guides to effectively convey timely information about service changes, library resources, and to improve outreach activities to our patron community while the library’s physical building was closed to its students, faculty, and staff.

Expression, Purification And Refolding Of A Human Na V 1.7 Voltage Sensing Domain With Native-Like Toxin Binding Properties, Ryan V. Schroder, Leah S. Cohen, Ping Wang, Joekeem D. Arizala, Sébastien F. Poget

Publications and Research

The voltage-gated sodium channel NaV1.7 is an important target for drug development due to its role in pain perception. Recombinant expression of full-length channels and their use for biophysical characterization of interactions with potential drug candidates is challenging due to the protein size and complexity. To overcome this issue, we developed a protocol for the recombinant expression in E. coli and refolding into lipids of the isolated voltage sensing domain (VSD) of repeat II of NaV1.7, obtaining yields of about 2 mg of refolded VSD from 1 L bacterial cell culture. This VSD is known to be involved in the …

A Systematic Review Of Diet Quality Index And Obesity Among Chinese Adults, Isma'il Kadam, Sudeep Neupane, Jingkai Wei, Lee Ann Fullington, Tricia Li, Ruopeng An, Li Zhao, Amy Ellithorpe, Xinyin Jiang, Liang Wang

Publications and Research

Diet quality scores are designed mainly based on Western-style dietary patterns. They were demonstrated to be good indicators of obesity in developed but not developing countries. Several diet quality scores were developed based on the Chinese dietary guidelines, yet no systematic review exists regarding how they were related to obesity. We searched research articles published between 2000 and 2021 in PubMed, CINAHL, and Scopus databases. Both cross-sectional and prospective studies that examined the relationship between a diet quality score and weight, body mass index, obesity, or waist circumference conducted in a Chinese population were selected. From the 602 articles searched, …

Medieval Bodies, Elizabeth Mazzola

Open Educational Resources

A reading list for my Spring 2022 undergraduate seminar on Medieval Literature entitled "Medieval Bodies"

"Writing Unspeakable Things: Speechlessness, Abjection, And The Ethics/Aesthetics Of (Not) Representing Sexual Violence In Three Korean American "Comfort Women' Novels", M Laura Barberan Reinares

Publications and Research

This article analyzes “comfort women” novels by the Korean American authors Therese Park, Nora Okja Keller, and Chang-rae Lee in terms of the ethics and aesthetics of representing sexual violence through language. I specifically look at these authors’ stylistic strategies to describe rape in writing and how they (more or less successfully) avoid voyeuristic portrayals of the “comfort women” by controlling the narrative point of view and relying on traumatic “speechlessness” and abjection. Building on relevant notions from the fields of photography, cinematography, philosophy, and psychoanalysis, this analysis suggests that in-progress representations of rape in language become a futile project …

Deism Defined And Defended, Carlo Alvaro

Publications and Research

No abstract provided.

Career And Calling: Designing Your Self In Society, David Crismond

Open Educational Resources

Syllabus for FIQWS 10008 Career and Calling: Designing Your Self in Society

Black Sound Matter(S): The Sonic Soundscape Of Black Auditory Liberation, Todd Craig

Publications and Research

In an attempt to embody the practices of DJ rhetoric as it relates to sound studies as well as sonic composing, Todd Craig will not speak with his own voice. Instead, this entire SonicText will serve as documentation of a live composition that engages with the theme of "Black Sound Matter(s)." Deploying the concept of sonic lineage (Craig, forthcoming; Polson, 2019), this piece aims to radically transform this intellectual space through sonic and DJ rhetorical practices. Thus, Todd Craig's voice is inconsequential; instead, what is most critical is his collaborators: historical scholars and organic intellectual-musicologists starring as Black Musician-Griots. The …

Urgent Need For Integrated Pandemic Policies On Pathogen Spillover, Pallavi A. Kache, Sonila Cook, Nigel Sizer, Lee Hannah, Neil M. Vora

Publications and Research

No abstract provided.

Reports And Commands: Deciphering A Health Exhibition Using The Speaking Mnemonic, David H. Lee

Publications and Research

The Amazing You exhibition at the Tampa Museum of Science and Industry had over 400 different multimedia health exhibits. Visitors walked through life stages, from conception through death, the exhibits at first showcasing developmental milestones, then diseases and chronic conditions associated with ageing. Museum executives described the exhibition as a public health intervention that stressed disease prevention, screening and behaviour change. This piece considers the question: What makes an exhibition be a health intervention? To describe complexities of the communication environment I use a mnemonic device called SPEAKING, an acronym for ‘Scene/Setting, Participants, Ends, Act Sequence, Key, Instrumentalites, Norms and …

“Los Programadores Debieron Pensarse Como Dos Veces”: Exploring The Intersections Of Language, Power And Technology With Bi/Multilingual Students, Sara Vogel

Publications and Research

Critical computing approaches to K-12 Computer Science (CS) education aim to promote justice in computing and the wider world. Despite being intertwined with inequitable power dynamics in computing, issues of linguistic (in)justice have received less attention in critical computing. In this article, I draw on theoretical ideas from sociolinguistics and critical computing to analyze qualitative data collected in computing and technology-integrated language and humanities classes serving emergent bi/multilingual middle school students. Conversations about language, technology, and power were close at hand in focal classrooms, and surfaced in moments when students acted as users and critics of, and tinkerers with digital …

Conjunctional Concepts: The Conceptual Teaching Technique In Biology Classes, Igor V. Zaitsev

Publications and Research

Conceptual teaching relies on concepts in conjunction with a bigger conceptual category (or categories). Revealing and using conceptual conjunctions in the science classroom means teaching conceptually. To make conceptual teaching more accessible to biology instructors, a three-concept model was described to be used during a lecture. This model has allowed the author to develop a relatively simple method that starts with an active concept or concepts, then introduces conjunctional and supporting concepts to relate the content to other concepts and relevant real-world applications. This method is intended to help instructors in preparing to teach biological concepts conceptually, in order to …

Intergenerational Differences In Dietary Acculturation Among Ghanaian Immigrants Living In New York City: A Qualitative Study, Margrethe F. Horlyck-Romanovsky, Terry T.-K Huang, Ramatu Ahmed, Sandra E. Echeverria, Katarzyna Wyka, May May Leung, Anne E. Sumner, Melissa Fuster

Publications and Research

Dietary acculturation may explain the increasing risk of diet-related diseases among African immigrants in the United States (US). We interviewed twenty-five Ghanaian immigrants (Youth n 13, Age (Mean ± SD) 20 y±5⋅4, Parents (n 6) and Grandparents (n 6) age 58⋅7± 9⋅7) living in New York City (NYC) to (a) understand how cultural practices and the acculturation experience influence dietary patterns of Ghanaian immigrants and (b) identify intergenerational differences in dietary acculturation among Ghanaian youth, parents and grandparents. Dietary acculturation began in Ghana, continued in NYC and was perceived as a positive process. At the interpersonal level, parents encouraged youth …

Leveraging High-Resolution 7-Tesla Mri To Derive Quantitative Metrics For The Trigeminal Nerve And Subnuclei Of Limbic Structures In Trigeminal Neuralgia, Judy Alper, Alan C. Seifert, Gaurav Verma, Kuang-Han Huang, Yael Jacob, Ameen Al Qadi, John W. Rutland, Sheetal Patel, Joshua Bederson, Raj K. Shrivastava, Bradley N. Delman, Priti Balchandani

Publications and Research

Background: Trigeminal Neuralgia (TN) is a chronic neurological disease that is strongly associated with neurovascular compression (NVC) of the trigeminal nerve near its root entry zone. The trigeminal nerve at the site of NVC has been extensively studied but limbic structures that are potentially involved in TN have not been adequately characterized. Specifically, the hippocampus is a stress-sensitive region which may be structurally impacted by chronic TN pain. As the center of the emotion-related network, the amygdala is closely related to stress regulation and may be associated with TN pain as well. The thalamus, which is involved in the trigeminal …

Police Officers’ Best Friend?: An Exploratory Analysis Of The Effect Of Service Dogs On Perceived Organizational Support In Policing, Kenneth M. Quick, Eric L. Piza

Publications and Research

This study explored the effectiveness of a novel technique for police departments to support their officers and promote wellness: the use of service dogs. We evaluated officer perceptions in two mid-sized, municipal police departments that have wellness programs with a service dog that is permanently assigned to a full-time police officer handler: Groton and Naugatuck, Connecticut. We assessed 6 factors believed to influence police officer wellness including: operational and organizational stress using the Police Stress Questionnaire (McCreary & Thompson, 2006); topical stressors including those related to the COVID-19 pandemic, police use of force and community relations, and police reform efforts; …

Editorial: Pathogens, Pathobionts, And Autoimmunity, Linda A. Spatz, Gregg J. Silverman, Judith A. James

Publications and Research

No abstract provided.

The Naked Truth: A Comprehensive Clarification And Classification Of Current ‘Myths’ In Naked Mole‐Rat Biology, Rochelle Buffenstein, Vincent Amoroso, Blazej Andziak, Stanislav Avdieiev, Jorge Azpurua, Alison J. Barker, Nigel C. Bennett, Miguel A. Brieño‐Enríquez, Gary N. Bronner, Clive Coen, Martha A. Delaney, Christine M. Dengler‐Crish, Yael H. Edrey, Chris G. Faulkes, Daniel Frankel, Gerard Friedlander, Patrick A. Gibney, Vera Gorbunova, Christopher Hine, Melissa M. Holmes, Jennifer U. M. Jarvis, Yoshimi Kawamura, Nobuyuki Kutsukake, Cynthia Kenyon, Walid T. Khaled, Takefumi Kikusui, Joseph Kissil, Samantha Lagestee, John Larson, Amanda Lauer, Leonid A. Lavrenchenko, Angela Lee, Jonathan B. Levitt, Gary R. Lewin, Kaitlyn N. Lewis Hardell, Tzuhua D. Lin, Matthew J. Mason, Dan Mccloskey, Mary Mcmahon, Kyoko Miura, Kazutaka Mogi, Vikram Narayan, Timothy P. O'Connor, Kazuo Okanoya, M. Justin O'Riain, Thomas J. Park, Ned J. Place, Katie Podshivalova, Matthew E. Pamenter, Sonja J. Pyott, Jane Reznick, J. Graham Ruby, Adam B. Salmon, Joseph Santos‐Sacchi, Diana K. Sarko, Andrei Seluanov, Alyssa Shepard, Megan Smith, Kenneth B. Storey, Xiao Tian, Emily N. Vice, Mélanie Viltard, Akiyuki Watarai, Ewa Wywial, Masanori Yamakawa, Elena D. Zemlemerova, Michael Zions, Ewan St. John Smith

Publications and Research

The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but also because of unusual protective features (e.g. its tolerance of variable oxygen availability), which may be pertinent to several human disease states, including ischemia/reperfusion injury and neurodegeneration. A recent article entitled ‘Surprisingly long survival of premature conclusions about naked mole‐rat biology’ described 28 ‘myths’ which, those authors claimed, are a ‘perpetuation of beautiful, but falsified, hypotheses’ and impede our understanding of this enigmatic mammal. Here, we re‐examine each of …

Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

Publications and Research

Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of transcriptome, chromatin immunoprecipitation sequencing (CHIP-seq), Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq), proteomic and metabolite screening followed by carbon tracing and extracellular flux analyses we show that genetic and pharmacological AURKA inhibition elicits metabolic reprogramming mediated by inhibition of MYC targets and concomitant activation of Peroxisome Proliferator Activated Receptor Alpha (PPARA) signaling. While glycolysis is suppressed by AURKA inhibition, we note an increase in the oxygen consumption rate fueled by enhanced fatty acid oxidation (FAO), which was …

The Psychological Allure Of Alford: Why Innocents Plead Guilty, Johanna Hellgren

Dissertations, Theses, and Capstone Projects

The Alford plea allows defendants to maintain their innocence while accepting a plea. Although this plea is more prevalent than jury trials, it is largely unknown to both lay people and researchers (Redlich & Özdoğru, 2009). Legal scholars have argued that the Alford plea may present an undue influence on innocent defendants who may not otherwise accept a plea, while other assert that the Alford plea is a beneficial alternative for defendants who want to preserve their reputation (Ronis, 2009; Ward, 2004). However, no research to date has explored either of these assumptions.

The goals of the current research were …

Redlining, Neighborhood Decline, And Violence: How Discriminatory Government Policies Created Violent American Inner Cities, Richard Powell

Dissertations, Theses, and Capstone Projects

Background – The practice of redlining involved the US government categorizing certain communities, often those inhabited by people of color, as too risky for private investment. Because of the resulting disinvestment, many of those neighborhoods deteriorated throughout the latter half of the 20^th Century. It also fostered conditions in redlined neighborhoods, such as high concentrations of poverty, joblessness, and racial segregation that the criminological theory of Social Disorganization identifies as correlates of violent crime.

Research Objectives – This study sought to determine whether redlining influenced levels of social disorganization operationalized as high levels of poverty, unemployment, family disruption, and …

Teaching For Transformation: Developing Agency And Solidarity Consciousness In A Critical-Transdisciplinary, Garden-Based Urban Environmental Studies Program, Pieranna Pieroni

Dissertations, Theses, and Capstone Projects

This dissertation focuses on “Community Roots,” an instantiation of urban, garden-based environmental education that employs a “critical-transdisciplinary” design framework and pedagogies. The “crit-trans” construct, articulated by the Urban Environmental Studies Research Coven (Strong et. al., 2016) is offered as both a generative approach to liberatory (environmental) pedagogies with applications across the curriculum and as a form of resistance to neoliberal logics shaping educational (and other) settings. After situating Community Roots in its socio-environmental, institutional, historical and theoretical contexts, a detailed description of the course’s instantiation of crit-trans pedagogy is offered. Additionally, reflections of 14 youth and adult participants are analyzed, …