Digital Commons Network^™

Systemic Resilience: Covid-19 And Healthcare Quality In Acute Myocardial Infarction At Tertiary Medical Centers – A Nationwide Study From Taiwan, Shih-An Liu, Sheng-Hui Hung, Chih-Hung Ku, Yan-Ru Wang, Ching-I Chang, Pa-Chun Wang

Journal of Health Research

Background: The COVID-19 was a pandemic once in a century. This study aimed to review the quality of acute myocardial infarction (AMI) care during the COVID-19 pandemic from a national perspective.

Methods: A retrospective analysis was conducted using Joint Commission of Taiwan (JCT)’s national Taiwan Clinical Performance Indicator (TCPI) system AMI care data, in correlation with Taiwan Centers for Disease Control COVID-19 epidemiological information. The time frames of the current study were categorized into four periods, based on the four levels of epidemic prevention and response established by the Central Epidemic Command Center (CECC). Quality indicators among different periods were …

Factors Related To The Health Service Seeking Behaviors Of Buddhist Monks In Chiang Mai, Thailand, Nutthakit Sangkhan, Sineenart Chautrakarn, Waraporn Boonchieng, Surasak Saokaew, Pallop Siewchaisakul

Journal of Health Research

Background: Buddhist monks are considered a vulnerable population in terms of health; however, their health-seeking behaviors (HSB), and associated factors remain underexplored in Thailand. This study aims to investigate HSB and its determinants among Thai Buddhist Monk.

Methods: A cross-sectional study was conducted between February and March 2023 using a self-administered questionnaire. Stratified random sampling was applied. The questionnaire was based on an established HSB model. Multinomial logistic regression was used to identify factors associated with HSB across different levels of illness severity.

Results: A total of 385 monks surveyed, most preferred popular health care for mild illnesses and professional …

Risk Factors For Tuberculosis (Tb) Treatment Interruption Among New And Retreatment Tb Patients In West Kalimantan Province, Indonesia: A Retrospective Cohort Study, Agus Fitriangga, Alex Alex, Rita Aryati

Journal of Health Research

Background: Treatment adherence in tuberculosis (TB) remains a major public health challenge in Indonesia. In West Kalimantan, high treatment interruption rates are driven by geographic, socioeconomic, and healthcare factors. This study identifies the risk factors linked to treatment interruption in the province.

Methods: A retrospective cohort study was using the System Information of Tuberculosis (SITB) database from 2019 to 2022 (n = 12,052). We used Kaplan-Meier analysis and Cox regression to identify treatment interruption risk factors, considering patient characteristics and geographic disparities.

Results: The overall treatment interruption rate was 6.62 % among new patients and 2.87 % among retreatment …

Exploring Workplace Mental Health And Counseling Needs In Open University Staff: A Mixed-Methods Study, Pathanin Sangaroon, Oranuch Kanjanaprakorn, Araya Prasertchai, Worrawit Nakpan

Journal of Health Research

Background: Workplace mental health is a growing concern in higher education, especially in open and distance learning (ODL) settings, where staff face unique stressors. This study examines the mental health and counseling needs of academic and support staff at Sukhothai Thammathirat Open University (STOU), Thailand, using a biopsychosocial lens.

Methods: An explanatory sequential mixed-methods design was used. In the quantitative phase, 332 staff completed a questionnaire on mental health and biopsychosocial factors. Twelve participants then took part in interviews to explore their experiences and counseling preferences. Quantitative data were analyzed using stepwise regression, and qualitative data through thematic analysis. …

Happiness Among Socially Active Older Adults In Northern Thailand In The Post-Covid-19 Era, Manashakorn Pichaijumpol, Orathai Katkhaw, Taweewun Srisookkum, Tienthong Takaew, Sunanta Wongrattanakamon, Kannikar Chulong

Journal of Health Research

Background: Happiness is crucial for healthy aging, particularly in the post-COVID-19 context, as older adults face evolving social and psychological challenges. This study investigates the key factors influencing happiness among socially active older adults in Northern Thailand, focusing on income, regular physical exercise, and depressive symptoms as primary predictors.

Methods: A cross-sectional study was conducted with 798 socially active older adults, selected through purposive sampling. Data were collected between June and July 2024 using a self-administered questionnaire, which included the Thai Geriatric Depression Scale (TGDS) and the Gross National Happiness (GNH) Questionnaire. Multiple regression analysis using the enter …

Dermatological Primary Health Care Services For Older Adults In Thailand, Chinmanat Lekhavat, Jiruth Sriratanaban

Journal of Health Research

Background: The increasing population aging worldwide poses challenges to accessibility to dermatological care, especially in rural areas with limited dermatologist availability. Establishing dermatological primary health care (PHC) services for older adults is crucial for improving access, efficiency, and equity. However, no study has systematically explored such a system.

Method: This mixed-methods study employed a participatory action research (PAR) model to identify structural and procedural requirements, patient journeys, health needs, and expectations. Data were collected through focus groups, in-depth interviews, and surveys. Design thinking workshops, guided by PAR principles, were used to develop dermatological PHC services. A survey was conducted across …

Effects Of A Mobile Application-Based Self-Management Program On Health Knowledge, Health Behaviors, And Glycemic Control In Patients With Type 2 Diabetes Mellitus, Prapada Watcharanat

Journal of Health Research

Background: Managing diabetes in the elderly is challenging due to limited access to health education and support. While mHealth tools have improved self-management and glycaemic control, evidence in older populations is limited. This study evaluated the impact of a mobile app and telephone follow-up on diabetes knowledge, health behaviours, and HbA1C levels in elderly individuals with diabetes.

Methods: A quasi-experimental study with a non-equivalent control group design was conducted. A total of 210 elderly individuals with diabetes were recruited and assigned to one of three groups: a mobile application group, a telephone follow-up group, and a control group (70 participants …

Efficiency And Clinical Outcomes Of Platelet-Rich Plasma Therapy On Canine Coxofemoral Osteoarthritis, Patama Arunrattanakul, Kumpanart Soontornvipart

The Thai Journal of Veterinary Medicine

The purpose of this study was to find out the optimal technique to prepare plasma with the highest platelet concentration in platelet rich plasma (PRP), as well as determine the result of autologous PRP from the dogs with osteoarthritis (OA) condition. It was shown that the PRP could reduce inflammation, cell regeneration and enhance angiogenesis to support the injured tissue. This study was composed of two phases; the first phase aimed to find the best centrifugation speed and time that could be able to produce the plasma with the highest platelet concentration by conducting the experiment from a total of …

การกำหนดบทลงโทษทางปกครองและทางอาญาร่วมกันในกรณีความประมาทเลินเล่อของ ภาระผูกพันหลังการทำเหมืองขององค์กร: กรณีศึกษาเปรียบเทียบกฎระเบียบการทำเหมืองแร่ของประเทศอินโดนีเซีย ไทย และแอฟริกาใต้ (A Combined Imposition Of Administrative And Criminal Sanctions For Negligence Of Corporate Post-Mining Obligations: A Comparative Study Of Indonesian, Thailand, And South African Mining Regulations), Fachrian Rizki

Chulalongkorn University Law Journal

วิธีการทางกฎหมายอันเหมาะสมและบทบัญญัติของกฎหมายที่เพียงพอต่อการลงโทษนิติบุคลคลซึ่งละเลยหน้าที่อันต้องกระทำการหลังการขุดเหมืองแร่นั้นถือเป็นประเด็นในทางกฎหมายที่หลายประเทศทั่วโลกไม่ได้ให้ความสนใจเท่าไรนัก นอกจากการละเว้นหน้าที่ดังกล่าวโดยประมาทจะส่งผลร้ายทั้งทางตรงและทางอ้อมต่อสิ่งแวดล้อมและชุมชน บริเวณรอบพื้นที่แล้ว การกระทำดังกล่าวยังส่งผลเสียต่อตัวนิติบุคคลด้วย ในอินโดนีเซียมีผู้เห็นว่าการบังคับใช้มาตรการบังคับทางปกครองเพียงอย่างเดียวก็สามารถป้องปรามการกระทำดังกล่าวได้อย่างเพียงพอ แต่อย่างไรก็ตาม เมื่อได้ศึกษาเปรียบเทียบกฎหมายของอินโดนีเซียกับประเทศไทยและแอฟริกาใต้แล้ว พบว่ามีการใช้มาตรการทางอาญาควบคู่ไปกับมาตรการบังคับทางปกครอง ดังนั้น กรณีดังกล่าวจึงนำมาสู่ปัญหาของงานวิจัยฉบับนี้ว่า การบังคับใช้มาตรการทางอาญาควบคู่ไปกับมาตรการบังคับทางปกครองต่อความผิดฐานละเลยหน้าที่ที่พึงต้องกระทำหลังการขุดเหมืองแร่โดยประมาทจะมีผลสัมฤทธิ์มากกว่าการใช้มาตรการบังคับทางปกครองเพียงอย่างเดียวหรือไม่ และการใช้โทษทางอาญาในความผิดฐานดังกล่าวนั้นขัดต่อหลักความได้สัดส่วนและหลักการกำหนดความผิดในทางอาญาหรือไม่ บทความวิจัยนี้จึงมุ่งศึกษาปัญหาดังกล่าวโดยเน้นการวิเคราะห์หลักเกณฑ์ทางทฤษฎีที่เกี่ยวข้อง และเปรียบเทียบกฎหมายของประเทศไทยและแอฟริกาใต้

ความรับผิดทางแพ่งของบริษัทแม่ต่อผู้เสียหายที่ได้รับผลกระทบจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก (Parent Company’S Civil Liability To Victims Affected By A Subsidiary’S Hazardous Substance Contaminated Site), Patthanith Promarak

Chulalongkorn University Law Journal

งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาความรับผิดทางแพ่งของบริษัทแม่ต่อผู้เสียหายที่ได้รับผลกระทบจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก โดยเป็นการศึกษาวิจัยเอกสารจากบทบัญญัติกฎหมาย คำพิพากษาศาล หนังสือตำรา และบทความเชิงวิชาการที่เกี่ยวข้อง ทั้งในประเทศและต่างประเทศ ผลการศึกษาพบว่า ปัจจุบันพระราชบัญญัติส่งเสริมและรักษาคุณภาพสิ่งแวดล้อมแห่งชาติ พ.ศ. 2535 ยังไม่มีบทบัญญัติให้บริษัทแม่เข้ามารับผิดชอบในความเสียหายจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก หากบริษัทแม่มีส่วนร่วมในแหล่งกำเนิดมลพิษหรือกำกับดูแลบริษัทลูก แต่ขาดการยึดถือแหล่งกำเนิดมลพิษทางกายภาพหรือเจตนาเพื่อตนอย่างใดอย่างหนึ่งไป อันไม่ครบองค์ประกอบของการเป็นผู้ครอบครองที่ต้องรับผิดตามมาตรา 96 หากบริษัทแม่มีการกระทำที่ไม่คำนึงถึงความเป็นนิติบุคคลของบริษัทลูกที่ไม่ใช่การกระทำละเมิด หากแต่เป็นการใช้โครงสร้างความเป็นนิติบุคคลของบริษัทลูกในทางมิชอบ อันได้แก่ การใช้นิติบุคคลเป็นเครื่องมือเพื่อหลบเลี่ยงหรือรับหน้าที่หรือความรับผิด และการมีทรัพย์สินปะปนกัน ดังนั้น จึงสมควรกำหนดบทบัญญัติที่เกี่ยวกับความรับผิดของบริษัทแม่ภายใต้พระราชบัญญัติดังกล่าว เพื่อให้ผู้เสียหายในคดีมลพิษจะได้รับความเป็นธรรมในการเยียวยา

ปัญหาของการตีความข้อยกเว้นด้านความมั่นคงตามมาตรา Xxi(B) ขององค์การการค้าโลก (Issues With The Interpretation Of Security Exceptions Under Article Xxi(B) Of The World Trade Organization), Nitinun Leethanakul

Chulalongkorn University Law Journal

บทความวิจัยนี้ศึกษาพัฒนาการของการตีความมาตรา XXI(b) ขององค์การการค้าโลก (WTO) เกี่ยวกับข้อยกเว้นด้านความมั่นคง ตั้งแต่ยุค GATT จนถึงปัจจุบัน โดยวิเคราะห์แนวปฏิบัติและคำวินิจฉัยในการยกอ้างข้อยกเว้นนี้ ผลการศึกษาพบว่า ในยุค GATT และ WTO ตอนต้น การตีความมาตรา XXI ยังขาดความชัดเจน โดยมีการอ้างอิงข้อยกเว้นนี้น้อยมาก และในกรณีที่มีการอ้างอิง ส่วนใหญ่มักยุติด้วยการเจรจา ตกลงกันโดยไม่ผ่านกระบวนการวินิจฉัยที่จะก่อให้เกิดบรรทัดฐานหรือแนวปฏิบัติ อย่างไรก็ตาม นับตั้งแต่ยุคสงครามการค้า การอ้างอิงข้อยกเว้นนี้ตามมาตรา XXI(b) ได้แพร่หลายมากขึ้น และคณะกรรมการวินิจฉัยข้อพิพาทแห่ง WTO ได้แสดงแนวโน้มที่ชัดเจนยิ่งขึ้นในหลายประเด็น เช่น การให้รัฐใช้ดุลพินิจในส่วนของบทนำและเป็นอำนาจพิจารณาของคณะกรรมการวินิจฉัยข้อพิพาทในบทเฉพาะ การแบ่งองค์ประกอบของบทบัญญัติและการตีความ “ผลประโยชน์สำคัญในด้านความมั่นคง” แต่ยังคงมีประเด็นที่ไม่ชัดเจน โดยเฉพาะในเรื่องการตีความ “สถานการณ์ฉุกเฉินในความสัมพันธ์ระหว่างประเทศ” และขอบเขตการใช้ดุลพินิจของรัฐที่จะถูกตรวจสอบโดยคณะกรรมการวินิจฉัยข้อพิพาท

Antiplatelet Effects Of Angelica Dahurica Root Extract Without Gastric Lesion Formation In Rats, Pitiphat Srisom, Kasem Rattanapinyopituk, Uthai Sotanaphun, Rataya Luechapudiporn

The Thai Journal of Pharmaceutical Sciences

Background: Platelet aggregation plays a crucial role in hemostasis; however, excessive platelet activation can lead to thrombus formation, contributing to cardiovascular diseases. While aspirin (acetylsalicylic acid [ASA]) is commonly used as an antiplatelet agent, its longterm use is associated with gastrointestinal side effects. Angelica dahurica (AD), a traditional herbal remedy, has shown in vitro antiplatelet activity and cyclooxygenase enzyme inhibition. However, its in vivo effects on platelet aggregation and gastric safety remain unclear.

Objectives: This study aimed to investigate whether Angelica dahurica root extract (ADE) could inhibit platelet aggregation and prevent aspirin-induced gastric lesions.

Materials and Methods: AD was extracted …

Bone-Sparing Effects Of Pueraria Mirifica Extract On Bone Loss In Androgen-Deficient Cynomolgus Macaques (Macaca Fascicularis), Thaweechai Saetae, Taratorn Kemthong, Sukanya Jaroenporn, Suchinda Malaivijitnond

The Thai Journal of Pharmaceutical Sciences

Background: Synthetic estrogens provide remarkable benefits for bone health in men; however, they also present several drawbacks after long-term use. Pueraria mirifica, a phytoestrogen-rich herb, has garnered attention due to its positive effects and minimal adverse side effects on bone in females. Most research on bone health has been conducted on rodents; however, bone architecture and remodeling in rodents differ from those in humans, making it challenging to apply the results to clinical trials.
Objectives: Thus, this study assessed the bonesparing effects of P. mirifica extract (PME) in androgen-deficient male cynomolgus macaques.

Materials and Methods: Adult male macaques were divided …

Quality By Design Approach To Method Development And Validation For Quantitative Estimation Of Dapagliflozin And Linagliptin In Pharmaceutical Tablet Dosage Forms, Prechha Shrestha, Ashwinee Kumar Shrestha, Rajan Shrestha, Barsha Thapa

The Thai Journal of Pharmaceutical Sciences

Objectives: The present study utilizes a quality by design approach to develop a simple, robust, and stability-indicating high-performance liquid chromatography method for quantifying dapagliflozin (DAPA) and linagliptin (LINA) in a fixed-dose combination and validate it according to the ICH-Q2 (R1) guidelines.

Materials and Methods: The effect of critical method parameters (CMPs), namely percentage of acetonitrile (ACN), pH of the buffer, and flow rate, on critical quality attributes (CQAs) such as retention time, area, tailing factor, and theoretical plates was studied using Box–Behnken design (BBD). Response optimizer was utilized to optimize the experimental conditions. The mobile phase (MP) consisted of ACN …

Cytotoxic And Anti-Inflammatory Activities Of Extracts Of Pra-Sa-Ka-Phrao Remedy And Its Plant Components, Theeraphong Ninlaor, Arunporn Itharat, Srisopa Ruangnoo, Pakakrong Thongdeeying, Sunita Makchuchit, Pranporn Kuropakornpong, Settakul Boonyasakseree, Chadchom Choockong, Ninnart Intharit, Neal M. Davies

The Thai Journal of Pharmaceutical Sciences

Background: Pra-Sa-Ka-Phrao (PSKP) is a traditional Thai remedy recognized in the National List of Essential Herbal Medicines of Thailand. It is traditionally used for treating flatulence and colic pain. It consists of eight components derived from plants with Ocimum tenuiflorum leaves as a main ingredient. However, there are no reports regarding the biological activities and chemical composition of PSKP.

Objectives: This study aimed to investigate cytotoxic activities, using cell lines related to the gastrointestinal (GI) system, and anti-inflammatory activities, along with chemical composition, of the PSKP complete formula (PSKPC) and a modified incomplete formula (PSKPIC).

Materials and Methods: Two extraction …

Continuous Glucose Monitoring Versus Self-Monitoring For Patients With Type 1 Diabetes: A Systematic Review And Meta-Analysis, Prayuth Poowaruttanawiwit, Kwanchai Rattanamanee, Nonnachanok Chaiyot, Saranpreeya Srisinroongruang

The Thai Journal of Pharmaceutical Sciences

Background: Patients with type 1 diabetes mellitus (T1DM) require intensive glucose monitoring to achieve optimal glycemic control and prevent complications. While self-monitoring of blood glucose (SMBG) has long been the standard approach, continuous glucose monitoring (CGM) offers real-time data and trend analysis that may enhance clinical decision-making.

Objective: This study aimed to evaluate whether CGM provides superior glycemic outcomes compared with SMBG in individuals with T1DM.

Materials and Methods: A systematic review and meta-analysis were conducted following preferred reporting items for systematic reviews and meta-analyses guidelines. Four randomized controlled trials involving T1DM patients using either CGM or SMBG were included. …

Isocratic Reversed-Phase High-Performance Liquid Chromatography Approach To Quantify Flutamide In Pharmaceuticals, Siddaraju Chikkalingaiah, Prathima Chikkegowda, Rajendraprasad Nagaraju

The Thai Journal of Pharmaceutical Sciences

Background: A non-steroidal antiandrogen, flutamide (FA), has been used often to treat advanced prostate cancer. It blocks testosterone’s tendency to bind to androgen receptors inside cells in some of the target organs, such as hair follicles, the prostate gland, skin, and testicles.

Objective: The main focus of the work is to produce an economical and reliable reversed-phase high-performance liquid chromatography technique for the quantitative study of FA in bulk materials and pharmaceuticals.

Materials and Methods: The elution of FA was done by running a mobile phase prepared by mixing 10 mM ammonium formate-formic acid buffer (pH-4) with methanol in the …

Screening And Evaluation Of Thai Herbal Plants As Multifunctional Agents For Targeting Amyloid Β Pathogenesis In Alzheimer's Disease, Ruedeemars Yubolphan, Suchinda Malaivijitnond, Sukanya Jaroenporn

The Thai Journal of Pharmaceutical Sciences

Background: Alzheimer's disease (AD) is a neurodegenerative disorder driven by complex pathophysiological processes. Current therapeutic strategies emphasize the development of multifunctional agents, particularly those derived from natural sources, to target multiple stages of the amyloid β (Aβ) cascade, a central contributor to AD pathology.

Objectives: This study aimed to investigate the anti-Aβ activity of nine Thai herbs and evaluate their potential as multifunctional agents for AD treatment.

Methods: Nine Thai herbs—Caesalpinia sappan (CS), Thunbergia laurifolia (TL), Rhinacanthus nasutus (RN), Tabernaemontana divaricata (TD), Cyperus rotundus (CR), Terminalia chebula (TC), Azadirachta indica (AI), Piper retrofractum (PR), and Asparagus racemosus (AR)—were screened …

Hematologic And Serum Biochemical Reference Intervals For Formosan Sika Deer (Cervus Nippon Taiouanus) From A Semi-Free-Ranging Population In Taiwan, Chen-Wei Wang, Ke-Lun Chen, Hung-Yi Wu, Chia-Ying Lin

The Thai Journal of Veterinary Medicine

The Formosan sika deer (Cervus nippon taiouanus), an endemic Taiwanese subspecies, holds a pivotal role in local conservation. This study addresses a significant knowledge gap by establishing population-specific reference intervals (RIs) for this species, as existing RIs are based on limited captive populations and may not accurately reflect the health of semi-free-ranging cohorts. We analyzed 632 sampling events from 232 healthy adult deer within Kenting National Park over 12 years (2013–2024). This study adhered to ASVCP guidelines, establishing instrument-specific RIs and employing linear mixed-effects models (LMMs) to evaluate the complex interactions among analytical instruments, sex, and body weight. …

Innovative Glycerin Impregnation Of Female Livestock Genital Organs And Satisfaction Assessment For Veterinary Anatomy Education In Thailand, Paisan Tienthai, Jantima Intarapanya, Pawana Chuesiri

The Thai Journal of Veterinary Medicine

Veterinary anatomy education faces several challenges, including increasing student enrollment, regulatory restrictions on animal use, and limitations of traditional preservation methods. Formalin preservation poses health risks, while plastination is costly and lacks flexibility. The conventional and modified Elnady Techniques present a safer and more cost-effective alternative, offering soft and flexible specimens; however, the adverse features still appear, and some steps require expensive equipment. This study aims to refine these Elnady Techniques, called ‘innovative glycerin impregnation’ for preserving female reproductive organs by reducing costs and simplifying the process using basic equipment. Additionally, veterinary students' satisfaction with glycerin-preserved specimens was compared to …

Blood Glucose Concentration In Highly Prolific Sows Before Farrowing: Its Relationship With Parity And Litter Size, Preechaphon Taechamaeteekul, Silvia Comencini, Fabio De Rensis, Roberta Saleri, Padet Tummaruk

The Thai Journal of Veterinary Medicine

Farrowing is an energy-demanding period for prolific sows, with blood glucose levels serving as key indicators affecting farrowing outcomes and piglet survival. This study aimed to evaluate blood glucose levels in prolific sows prior to farrowing, assess the prevalence of hypoglycemia in late gestation, and investigate the relationship between blood glucose levels, parity, and litter size under tropical conditions. A total of 67 Danish Landrace × Yorkshire sows were grouped based on litter size (6–14, 15–17, or ≥18 piglets) and parity (2–4 and 5–6). To determine glucose levels, blood samples were collected at 115.8 ± 1.6 days of gestation, at …

Bacterial Identification And Antibiotic Sensitivity Profiles From Captive Birds At Taipei Zoo, Younjung Chang, I-Li Liu, Jane-Fang Yu, Lih-Chiann Wang

The Thai Journal of Veterinary Medicine

Bacterial infections are common in zoo birds. They may be caused by pathogenic bacteria or opportunistic bacteria due to trauma or stress-induced immune compromise. Improper use of antibiotics contributes to the development of resistant bacteria, making treatment complicated or ineffective. However, comprehensive clinical investigations into bacterial prevalence and antibiotic susceptibility in zoo-captive birds remain limited. This study identified the bacterial species present in captive diseased birds at the zoo and conducted a 12-year analysis of their antibiotic susceptibility profiles. The specimens from 48 birds at Taipei Zoo from 2006 to 2017 were submitted to a commercial reference laboratory for bacterial …

Assessing Market Potential And Swot-Based Strategies For Betong Chicken In Pattani, Yala, And Narathiwat Provinces Of Southern Thailand, Talerngsak Angkuraseranee, Chaiyawan Wattanachan, Kettawan Boonthep

The Thai Journal of Veterinary Medicine

This study aimed to evaluate market opportunities and formulate strategic pathways for the sustainable growth of Betong chicken, an indigenous premium poultry breed in southern Thailand known for its distinctive meat quality. Recent declines in the Betong chicken population and productivity have created a supply–demand imbalance, threatening the Betong chicken’s long-term economic viability. Using a mixed-methods design, data were collected from 280 stakeholders—farmers, processors, retailers, and consumers—in Pattani, Yala, and Narathiwat provinces. SWOT and Internal–External (IE) matrix analyses were applied to identify internal strengths and weaknesses and external opportunities and threats. The External Factor Evaluation (EFE) score of 2.773 indicated …

Computed Tomography Features For Differentiating Mast Cell Tumors And Soft Tissue Sarcomas In Subcutaneous Masses In Dogs, Seri Hong, Daji Noh, Kija Lee, Hojung Choi, Youngwon Lee, Sooyoung Choi

The Thai Journal of Veterinary Medicine

This study aimed to investigate the computed tomography (CT) features of mast cell tumors (MCTs) and soft tissue sarcomas (STSs) in subcutaneous masses of dogs and to identify distinguishing characteristics between these two tumor types. This retrospective, multicenter study included 22 dogs with subcutaneous masses diagnosed as MCTs (n = 11) or STSs (n = 11) via fine needle aspiration or excisional biopsy. The CT features were evaluated based on four categories: location, morphological characteristics (including shape, margin, capsulation, size, and long axis to short axis (L/S) ratio of the lesion), internal parenchymal characteristics (including cavitation, vascularization, mineralization, homogeneity and …

Possible Cross-Resistance And Horizontal Gene Transfer Associated With Halquinol In Escherichia Coli And Salmonella Enterica Isolated From Pigs, Nisit Chansong, Songsak Srisanga, Nutthavut Mahawatthanaunkul, Rungtip Chuanchuen

The Thai Journal of Veterinary Medicine

The aims of this study were to determine the possible cross-resistance and horizontal gene transfer associated with halquinol in Escherichia coli and Salmonella spp. from pigs. Two of each E. coli and Salmonella isolates exhibiting low halquinol MIC (8 and 16 µg/ml, respectively) and susceptible to antibiotics tested were selected for in vitro stepwisehalquinol exposure experiment. Another E. coli (n=19) and Salmonella (n=6) isolates with high halquinol MICs (16-64 and 32-64 µg/ml, respectively) containing plasmids were used for transferability testing of halquinol resistanceencoding gene(s) using filter mating method. In vitro exposure to subinhibitory concentrations of halquinol promoted neither resistance to …

Fetal Losses Associated With Prrsv, Ppv, And Pcv2 Detection, Em-On Olanratmanee, Pachara Pearodwong, Duangkamol Lewchalermwong, Padet Tummaruk

The Thai Journal of Veterinary Medicine

This study aimed to investigate the prevalence of porcine reproductive and respiratory syndrome virus (PRRSV), porcine parvovirus (PPV), and porcine circovirus type 2 (PCV2) infections associated with fetal losses in 10 commercial swine herds in Thailand. Samples were collected from 100 sows and included 25 aborted fetuses, 35 mummified fetuses, and 40 stillborn piglets. The average parity number of the sows was 2.8 ± 2.4, ranging from 0 to 11. Fetal age was determined based on either the day of abortion or estimated using crown-rump length, and categorized as ≥70 days. Organs from each case were pooled, homogenized, and tested …

Preliminary Study Of A Support System For Noninvasive Pneumonia Detection Using Breath Sound Analysis In Calves, Yasuhiro Morita, Seiji Inoue, Satoshi Ohkura

The Thai Journal of Veterinary Medicine

Pneumonia in calves is caused by a complex association between host, pathogen, and environmental factors, and it is challenging to detect the subclinical stages. Therefore, it is crucial to accurately and rapidly identify calves with pneumonia on farms to provide appropriate treatment in a timely manner. In the present study, we focused on the frequency components of lung sounds to distinguish calves with and without pneumonia, without the need for veterinary expertise. In addition, we evaluated the pathogenesis of pneumonia by clarifying the relationship between the frequency components of lung sounds and lung ultrasound findings in calves. Although further case …

Paediatric Fixed Drug Eruption: A Case Report Of Ofloxacin As The Culprit, Ambika Nand Jha, Varsha Ratan Gaikwad, Rabia Alam, Shivanshu Sharma, Ashok Kumar Gupta

Chulalongkorn Medical Journal

Ofloxacin, a second-generation fluoroquinolone, is a relatively rare but documented cause of fixed drug eruption (FDE), a localized cutaneous hypersensitivity reaction marked by recurrent, well-demarcated erythematous patches or macules that may develop into blisters upon re-exposure to the offending agent. The underlying mechanism is immune-mediated, involving T-cell activation, cytokine release, and keratinocyte apoptosis. A 5-year-old boy weighing 15 kg was prescribed Ofloxacin syrup (7.5 ml twice daily) and Paracetamol suspension (5 ml twice daily) for suspected enteric fever. Within two days, he developed several annular erythematous lesions on his hands and back, associated with intense itching, raising suspicion of a …

Neutrophil-To-Lymphocyte, Monocyte-To-Lymphocyte, And Platelet-To-Lymphocyte Ratio In Acute Hospitalized Patients With Schizophrenia, Apichan Dangrungroj, Mayteewat Chiddaycha

Chulalongkorn Medical Journal

Background: Schizophrenia has been increasingly linked to inflammation. The neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) have emerged as potential indicators of systemic inflammation.

Objectives: The objectives are to compare NLR, MLR, and PLR between patients with schizophrenia and healthy controls, and to investigate the factors associated with NLR. Methods: This retrospective study included 102 sex- and age-matched patients hospitalized with schizophrenia and control subjects. NLR, MLR, and PLR were calculated from the Complete Blood Count (CBC) results and compared between groups. Sociodemographic data and clinical characteristics were analyzed using multiple linear regression to identify …

Comparison Of Blood And Urinary Ketamine Profiles Among Different Causes Of Death In Thai Postmortem Cases, Supanida Leungsukjaroen, Sunitda Khawthong, Peerayuht Phuangphung

Chulalongkorn Medical Journal

Background: Ketamine is a substance that is commonly abused, especially in young adults. Blood and urinary ketamine profiles are important for the interpretation of causes of death. Objective: To compare blood and urinary ketamine profiles between different causes of death in Thai postmortem cases.

Methods: A cross-sectional study was conducted in 40 Thai postmortem cases whose urine samples tested positive for ketamine. Sex, age, cause of death, manner of death, blood alcohol concentration (BAC), and concomitant drugs found with ketamine in subjects were recorded for each case. Blood and urinary ketamine and its two metabolites (norketamine and dehydronorketamine …