Digital Commons Network^™

"Mawlum" Performance As A Diabetes Health Communication Intervention In Northeastern Thailand: A Concept Paper, Prathurng Hongsrangon, Rachan Huaysai, Vachira Ruttanapet, Monthalee Nooseisai, Samlee Plianbangchang

Journal of Demography

No abstract provided.

Influences Of Standard Of Living, Fertility And Health On Saving: Empirical Evidence From Five Asean Countries, Supachet Chansam

Journal of Demography

No abstract provided.

Causal Relationship Among Wealth, Health And Fertility In Thailand, Supachet Chansam

Journal of Demography

No abstract provided.

Marital Status And Self-Assessed Health Of Elderly Thais, Wiraporn Pothisiri, Pataporn Sukontamarn, Vipan Prachaubmah

Journal of Demography

No abstract provided.

A New Demographic Strategy For Point-Of-Need Medical Testing: Linking Health Resource Scores, Poverty Levels, And Care Paths, Gerald Joseph Kost, Pratheep Katip, Anan Kanokslip, Daniel M. Mecozzi

Journal of Demography

No abstract provided.

Resource And Financial Management For Cities And Health, Kua Wongboonsin, Kaemthong Indaratna

Journal of Demography

No abstract provided.

Planning And Public Health, Adit Laixuthai, Tom Connelly

Journal of Demography

No abstract provided.

Effects Of Ball Milling Duration And Sintering Temperature On Mechanical Alloying Fe3si, Varistha Chobpattana, Chakansin Phoomkong, Peerawat Nutnual, Kritsada Thaengthong, Wanchai Pijitrojana

Journal of Metals, Materials and Minerals

Fe3Si is under interest as a ferromagnetic electrode of magnetic tunneling junctions (MTJs). Its crystalline structure is important for achieving high device efficiency. This work focuses on mechanical alloying of 3:1 ratio of 99% pure Fe and Si powder mixtures by ball milling and sintering. The mixtures were ball-milled for various durations up to 20 h. Then, they were sintered from 400°C  to 800°C for 4 h in Ar.  SEM images and particle size analysis show significant reduction in average particle size of the mixtures after ball milling for 20 h. The longer duration of ball milling process promotes powder …

A Combination Of Hyoscyamine And Theophylline For Treatment Of Sick Sinus Syndrome In A Dog, Uraiwan Saengkieo, Arisara Kiatsilapanan, Suwanakiet Sawangkoon

The Thai Journal of Veterinary Medicine

A-12-year-old female West Highland White Terrier presented with a history of cardiac syncope. Physical examination revealed bradycardia. Sick sinus syndrome (SSS) was diagnosed with electrocardiography and 24-hour Holter monitoring. However, the owner made the decision to receive the pharmacological therapy. Therefore, a combination of hyoscyamine sulfate and theophylline was prescribed. Following two adjustments of drug dosage and frequency within a year, the total number of heartbeats increased from 58,091 to 73,686 beats, and the mean heart rate increased from 44 to 59 bpm. After the treatment, the dog became stable and no syncopal episodes were detected, despite the presence of …

Sertoli Cell Tumor In A Boar: Pathological And Immunohistochemical Comparison With Canine Cases, Anurak Tibboo, Hataitip Changchum, Nuttiya Saengrueng, Panvard Unjai, Natchanon Dumniem, Kasem Rattanapinyopituk, Komkrich Teankum

The Thai Journal of Veterinary Medicine

Sertoli cell tumors (SCTs) are sex cord–stromal tumors of the testis that are common in dogs but rare in boars. This study characterized the pathological features of an SCT in a boar and compared its immunohistochemical profile with that of canine SCTs. Testicular tissues from boars (SCT, n = 1; normal testes, n = 2) and dogs (SCT, n = 3; normal testes, n = 5) were evaluated by histopathology and immunohistochemistry for proliferating cell nuclear antigen (PCNA), vimentin, and cytokeratin. Gross examination revealed a solitary, well-circumscribed nodule in the left testis of the boar, accompanied by severe bilateral testicular …

Exploratory Concurrent Associations Between K-Kyphometer And Flexicurve-Derived Kyphosis Measures (Kyphosis Index And Kyphosis Angle): Preliminary Study, Pimonpan Taweekarn, Kunavut Vannajak

Journal of Health Research

Background: Quantifying thoracic kyphosis is essential in musculoskeletal and rehabilitation practice. Although radiographic Cobb angle is commonly treated as a reference standard, repeated imaging is limited by cost and radiation exposure. Therefore, clinicians frequently use non-radiographic tools such as inclinometers and flexicurve rulers, which have shown acceptable reliability and variable levels of validity in different populations. The objective of this study was examine Pearson correlations between a patented K-Kyphometer (Utility Patent No. 23366) and two flexicurve-derived measures—Kyphosis Index (KI) and Kyphosis Angle (K angle).

Methods: In this cross-sectional correlation study (N=28), thoracic kyphosis was assessed using the K-Kyphometer and …

Effectiveness Of An Integrated Activity-Based And Tele-Monitoring Intervention On Mental Health Literacy And Resilience Among Urban Older Adults In Thailand: A Quasi-Experimental Study, Khunatpakorn Makkabphalanon, Pramote Thangkratok, Jutamast Wongjan, Natchaya Palacheewa

Journal of Health Research

Background: Mental health problems among older adults are a growing public health concern, particularly in urban areas. Mental health literacy can enhance problem recognition, self-help, and help-seeking. This study examined changes in mental health literacy and resilience among urban older adults following an integrated activity-based and tele-monitoring intervention.

Methods: A one-group quasi-experimental repeated-measures study was conducted among 30 adults aged 60 years and older in urban communities in Thailand. Participants received a structured 3-hour activity-based mental health literacy intervention followed by 1 month of tele-monitoring support. Data were collected at baseline, immediately after the intervention, and at 1-month follow-up. Changes …

Effect Of A Plant-Based Sweet Potato And Almond Snack Bar, High Intensity Interval Training, And Mindfulness Therapy On Blood Glucose Control Among Patients With Type 2 Diabetes Mellitus In Medan Selayang District, Medan, Indonesia, Henny Arwina Bangun, Ermi Girsang, Santi Deasy Siregar, Rapael Ginting, Putranto Manalu, Yenni Gustiani Tarigan, Baxter Hepburn Kachingwe

Journal of Health Research

Background: Integrated lifestyle interventions combining nutritional, physical, and psychological strategies may improve glycemic control in individuals with type 2 diabetes mellitus (T2DM). However, evidence regarding the combined effects of high-fiber functional foods, high-intensity interval training (HIIT), and mindfulness therapy remains limited, particularly in low- and middle-income countries. This study evaluated the effects of a multimodal lifestyle intervention on glycemic responses among individuals with T2DM and non-diabetic adults.

Methods: A quasi-experimental pilot study was conducted among 30 female participants (15 with T2DM and 15 non-diabetic controls) in Medan, Indonesia. Fasting (pre-prandial) and post-prandial blood glucose concentrations were measured repeatedly throughout the …

การกำหนดนับอายุความหมิ่นประมาทออนไลน์: ศึกษาหลัก Single Publication Rule (Limitation Periods For Online Defamation: A Study Of The Single Publication Rule), Warut Songsujaritkul

Chulalongkorn University Law Journal

การเผยแพร่ข้อมูลบนสื่อออนไลน์มีลักษณะคงอยู่อย่างถาวรและสามารถเข้าถึงได้ตลอดเวลา เมื่อข้อความอันอาจเป็นการหมิ่นประมาทถูกเผยแพร่ผ่านแพลตฟอร์มดิจิทัล ปัญหาทางกฎหมายจึงเกิดขึ้นว่าควรเริ่มนับอายุความเมื่อใด เนื่องจากภายใต้หลักการเผยแพร่หลายครั้ง (Multiple Publication Rule) การเข้าถึงเนื้อหาแต่ละครั้งอาจถูกตีความว่าเป็นการกระทำความผิดใหม่ ส่งผลให้อายุความถูกขยายออกไปอย่างไม่มีที่สิ้นสุด ทำให้ผู้เผยแพร่ต้องเผชิญความเสี่ยงทางกฎหมายอย่างไม่มีกำหนด อันก่อให้เกิดผลกระทบเชิงยับยั้ง (chilling effect) ต่อเสรีภาพในการแสดงความคิดเห็น และเกิดความไม่สมดุลระหว่างเสรีภาพในการแสดงความคิดเห็นกับสิทธิในชื่อเสียงของบุคคล บทความวิจัยนี้ศึกษาวิเคราะห์มิติปัญหาทางกฎหมายว่าด้วยการกำหนดจุดเริ่มต้นการนับอายุความของความผิดฐานหมิ่นประมาทที่กระทำผ่านสื่อออนไลน์ โดยมีขอบเขตการศึกษาครอบคลุมถึงแนวคิดว่าด้วยการสร้างดุลยภาพระหว่างเสรีภาพในการแสดงความคิดเห็นกับการคุ้มครองชื่อเสียง การตรวจสอบหลักเกณฑ์การนับอายุความตามประมวลกฎหมายอาญาและประมวลกฎหมายแพ่งและพาณิชย์ของไทย และการศึกษาเปรียบเทียบพัฒนาการ บรรทัดฐานคำพิพากษา และบทบัญญัติทางกฎหมายของประเทศอังกฤษและสหรัฐอเมริกาที่นำหลัก Single Publication Rule มาปรับใช้ ผลการศึกษาพบว่า การปรับใช้หลักการนับอายุความแบบเดิมที่ถือว่าการเผยแพร่ซ้ำแต่ละครั้งเป็นความผิดใหม่ไม่สอดคล้องกับลักษณะของสื่อออนไลน์ และก่อให้เกิดภาระเกินสมควรแก่ผู้เผยแพร่ จึงควรนำหลัก Single Publication Rule มาใช้ โดยถือว่าการเผยแพร่เนื้อหาที่มีสาระสำคัญเดียวกันเป็นการกระทำเพียงครั้งเดียวและเริ่มนับอายุความนับแต่วันที่เผยแพร่ครั้งแรก เว้นแต่การเผยแพร่ครั้งหลังจะมีความแตกต่างอย่างมีนัยสำคัญจึงจะถือเป็นการเผยแพร่ใหม่ อย่างไรก็ดี การนำหลักดังกล่าวมาใช้ควรกำหนดรายละเอียดและกลไกทางกฎหมายเพิ่มเติม อาทิ การให้ดุลพินิจแก่ศาลในการขยายอายุความ การกำหนดขอบเขตระยะเวลาและการนับอายุความจากวันที่เผยแพร่ครั้งแรกให้ชัดเจน ตลอดจนมาตรการที่ใช้บังคับกับคลังข้อมูล แพลตฟอร์ม และผู้เผยแพร่ เพื่อสร้างความสมดุลระหว่างเสรีภาพในการแสดงความคิดเห็นกับสิทธิในชื่อเสียง ให้สอดคล้องกับบริบทของสังคมดิจิทัล

แนวทางการคุ้มครองสิทธิอนามัยเจริญพันธุ์สตรีและผู้ที่มีความหลากหลายทางเพศในบริบทของประเทศไทย (The Protection Of Reproductive Health Rights Of Women And Lgbtqian+ Persons In The Context Of Thailand), Chattrika Napatanapong, Nichakorn Khonthong

Chulalongkorn University Law Journal

บทความนี้มุ่งศึกษาถึงการคุ้มครองสิทธิอนามัยเจริญพันธุ์ของสตรีและผู้มีความหลากหลายทางเพศในบริบทประเทศไทย ภายใต้พันธกรณีระหว่างประเทศด้านสิทธิมนุษยชน เช่น อนุสัญญาว่าด้วยการขจัดการเลือกปฏิบัติต่อสตรีในทุกรูปแบบ (CEDAW) หลักการยอกยาการ์ตา และเป้าหมายการพัฒนาที่ยั่งยืนข้อที่ 5 ซึ่งต่างยืนยันถึงสิทธิในการเข้าถึงสุขภาพทางเพศและอนามัยเจริญพันธุ์อย่างเสมอภาคและปราศจากการเลือกปฏิบัติ จากการศึกษาพบว่า แม้ประเทศไทยจะมีความก้าวหน้าในเชิงกฎหมายและนโยบาย แต่ยังคงเผชิญอุปสรรคสำคัญ อาทิ อคติจากผู้ให้บริการ ความเหลื่อมล้ำทางเศรษฐกิจและภูมิศาสตร์ ตลอดจนข้อจำกัดทางกฎหมายที่ยังไม่สอดคล้องกับมาตรฐานสิทธิมนุษยชนสากล การศึกษาวิจัยนี้จึงมุ่งศึกษาพัฒนาการและปัญหาทางกฎหมายและนโยบายของประเทศไทยที่เกี่ยวข้อง เช่น การยุติการตั้งครรภ์ การขยายสิทธิประโยชน์ด้านการคุมกำเนิด การบริการอนามัยเจริญพันธุ์ รวมถึงสิทธิในการเข้าถึงบริการยาฮอร์โมนและการยืนยันเพศสภาพ โดยศึกษาเปรียบเทียบกับการคุ้มครองสิทธิอนามัยเจริญพันธุ์ในสหราชอาณาจักร เยอรมนี และอินเดีย อันเป็นตัวอย่างการพัฒนากลไกกฎหมายและนโยบายที่ช่วยลดความเหลื่อมล้ำและสร้างระบบบริการที่เป็นมิตร เพื่อยกระดับกลไกทางกฎหมายและนโยบายสาธารณะของไทยให้สามารถส่งเสริมและสนับสนุนสิทธิอนามัยเจริญพันธุ์เกิดขึ้นจริง ภายใต้พันธกรณีระหว่างประเทศด้านสิทธิมนุษยชน และบรรลุเป้าหมายการพัฒนาอย่างยั่งยืนได้ต่อไป

Presumptive Feline Infectious Peritonitis-Associated Uveitis With Posterior Segment Mass-Like Lesions On Ultrasonography, Hyun-Wook Kim, Danbee Kwon, Joon Young Kim

The Thai Journal of Veterinary Medicine

5-year-old neutered male domestic shorthair cat was presented with unilateral anterior uveitis and ocular pain in the left eye without systemic signs. Ophthalmic examination revealed a superficial corneal ulcer, keratic precipitates, and aqueous flare. Ocular ultrasonography identified ciliary body thickening and a nodular mass-like lesion posterior to the ciliary body. Despite systemic corticosteroid treatment after corneal ulcer healing, no clinical improvement was observed. Computed tomography revealed contrast-enhancing thickening of the ciliary body and uveoscleral region. Enucleation and histopathology demonstrated pyogranulomatous inflammation without evidence of neoplasia or detectable infectious organisms. Immunohistochemistry for feline coronavirus antigen was not performed at that time. …

Expression Of Follicle Stimulating And Luteinizing Hormone Receptors In Porcine Testes After Timing The First Vaccination For Immunocastration, Sayamon Srisuwatanasagul, Rungrueang Yodsheewan, Amornthep Archawakulathep, Suvaluk Seesupa, Kongkiat Srisuwatanasagul, Atthaporn Roongsitthichai, Siriluck Juntautsa

The Thai Journal of Veterinary Medicine

This study aimed to examine the expression of follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHR) in the testes of male fattening pigs based on the timing of the first immunocastration dose. A total of 24 male pigs were randomly assigned to 3 groups: C (n=8) consisted of only intact pigs, T1 (n=8) contained those immunocastrated at 15 and 19 weeks of age, and T2 (n=8) was composed of those immunocastrated at 9 and 19 weeks of age. The expression of FSHR and LHR was evaluated using H-score from immunohistochemistry and protein band intensity from Western blotting. Immunohistochemistry …

Literacy And Competency In Thai Education : A Crosswalk Framework For Curriculum Design And Assessment, Wichai Sawekngam

Journal of Education Studies

This article aims to analyze and position the relationship between literacy and competency in the context of Thai education. It employs conceptual analysis and purposive document synthesis based on relevant international and Thai frameworks, including PIAAC, PISA/OECD, UNESCO, ACRL, the Council of the European Union, DigComp, UNESCO-UNEVOC, PISA Thailand, and CBE Thailand materials on core competencies and learning assessment. The analysis indicates that literacy and competency are related but cannot be used interchangeably. Literacy emphasizes domain-specific abilities to understand, evaluate, use, create, or communicate texts, data, media, symbols, or information in meaningful contexts. Competency, on the other hand, emphasizes the …

Guidelines For Inclusive Education Management For Students With Special Needs At Secondary Level In Physical Education, Nuttapad Sornprasan, Piyanan Jooronsiriphong, Suthana Tingsabhat

Journal of Education Studies

This research aimed to 1) examine the conditions and problems of inclusive physical education management for students with special needs at the secondary school level, and 2) propose appropriate guidelines for inclusive physical education management for students with special needs in secondary schools. Samples were 95 schools, the informants consisted of 3 groups, including heads of the Health and Physical Education Department, physical education teachers, and special education teachers. Multi-stage sampling and stratified sampling based on the four geographical regions of Thailand were used to recruit the samples. The research instrument was a questionnaire concerning inclusive physical education management for …

Holding The Line: Teacher Resilience And Engagement In Myanmar’S Conflict-Affected, Non-State Schools, Lugyi No, Hilary Lustick

Journal of Education Studies

This qualitative study explores teacher resilience, professional engagement, and informal leadership in community-led schools located in conflict-affected areas of Myanmar. The study draws on two online focus group discussions with 14 high school teachers selected through purposive sampling. The research instrument was a semi-structured focus group discussion protocol. The discussions were conducted in the Myanmar language, and the data were analyzed using inductive thematic analysis. The findings indicate that teachers sustain resilience through moral purpose, professional commitment, and strong relational ties with students, peers, and local communities. In the absence of formal governance structures, teachers assume informal leadership roles by …

Eco-Literacy As The Foundation Of Transformative Education: Integrating Theory, Practice, And Sustainable Development, Siriping Deedoo, Omsin Jatuporn

Journal of Education Studies

Eco-literacy has been widely recognized as a crucial body of knowledge and a key competency for citizens in the 21st century, as it forms the foundation for understanding the complex interrelationships among humans, nature, and society. This article has three main objectives, namely: 1) describe the theoretical foundations of Eco-literacy, 2) examine its development from past to present and 3) discuss the educational roles of integrating this concept into curricula and teaching practices. The review of literature shows that the development of the concept revealed that eco-literacy has evolved from an early emphasis on providing environmental science data to a …

Bmi-Perception Discordance And School Health Communication Profiles Among Us High School Students: Evidence From The 2023 Youth Risk Behavior Survey, Hoang Thanh Thu, Nguyen Khac Toan

Journal of Health Research

Background: Body mass index (BMI) screening is commonly used in schools to identify students at risk of overweight or obesity, but BMI alone may not adequately guide counselling when students’ perceived weight differs from BMI-based status.

Method: This cross-sectional secondary analysis used 2023 US Youth Risk Behavior Survey data from 17,814 students in grades 9–12. Survey-weighted estimates and logistic regression examined overweight or obesity, underestimation among students with overweight or obesity, and excessive concern among students without overweight or obesity.

Results: Overall, 30.63% of students had overweight or obesity. Among students reporting perceived weight, 53.04% were concordant, …

An Mhealth Application For The Rehabilitation Of Community-Dwelling Individuals With Chronic Mental Health Conditions: A Randomized Controlled Trial, Pornpat Hengudomsub, Pornpun Sudjai, Pornprasert Kaewkham, Kiattisak Raihinthaung

Journal of Health Research

Background: Developing a nursing service system to promote rehabilitation among individuals with chronic mental health conditions is essential for maintaining self-care and social functioning. This study examined the effectiveness of the BUU True Friends mobile application (mHealth) in enhancing rehabilitation and reducing relapse risk.

Methods: A two-arm, pretest–posttest randomized controlled trial (RCT) was conducted with 80 participants (aged 20–59) recruited from an outpatient service in Eastern Thailand. Participants were randomly assigned to an intervention group (n=40) receiving standard care plus the mHealth app, or a control group (n=40). Outcomes were assessed at baseline and after an eight-week intervention. Data were …

Preliminary Clinical Evaluation Of Inhalation Aromatherapy With Blended Essential Oils On Sleep Quality In Adults With Sleep Disturbance, Punyanut Amorndoljai, Laddawan Choothong, Surachai Techaoei, Em-On Chaiprateep

Journal of Health Research

Background: Sleep disturbances impact cognition and physiology. While individual essential oils are documented, a gap remains in how multi-component blends can target multiple pathways. This study evaluated a blended essential oil (BEO) systematically guided by Thai Traditional medicine (TTM) principles to balance the "Wind" element (Tard Lom) alongside modern neurobiological validation.

Methods: A one-group pretest–posttest quasi-experimental study was conducted in adults (aged ≥ 20 years, n = 38) with sleep disturbances (PSQI > 5). The BEO formulation consisting of orange (2.5% w/w), lavender (1.0% w/w), ylang-ylang (1.5% w/w), geranium (0.5% w/w), cedarwood (2.0% w/w), and rosewood (2.0% w/w) in 95% ethanol …

Latent Profile Analysis Of Physical And Cognitive Leisure Activity Level Among Chinese Middle-Aged And Older Adults: A Cross-Sectional Study, Zhenying Liang, Pankaew Tantirattanakulchai, Nuchanad Hounnaklang

Journal of Health Research

Background: The global aging trend has accelerated. This study tried to identify the factors related to different patterns of physical and cognitive leisure activities among Chinese middle-aged and older adults.

Method: Latent Profile Analysis was conducted to classify 12,480 participants aged 45 and above, followed by logistic regression to understand associations between activity profiles and related factors.

Results: Physical activity (n = 2,269) and cognitive leisure activity groups (n = 10,211) were identified according to their different levels of physical activity and cognitive leisure activity engagement. Middle-aged individuals (aOR = 1.42, 95% CI: 1.29–1.56), rural residents (aOR = 1.38, 95% …

Efficacy Of A Mouthwash Containing Standardized Centella Asiatica Extract (Eca 233) In Patients With Gingivitis: A Randomized Double-Blind Placebo-Controlled Trial, Alisa Awapark, Wanchai Chongcharoen, Mayuree H. Tantisira, Nattapon Rotpenpian

The Thai Journal of Pharmaceutical Sciences

Background: Gingivitis is the earliest and most reversible stage of periodontal disease, characterized by inflammation of the gingiva caused by the accumulation of plaque. In addition to removing plaque, mouthwash containing antiseptic or anti-inflammatory could be used as an adjunct therapy.
Objectives: The objective of this study is to evaluate the efficacy of a 0.10% standardized Centella asiatica extract (ECa 233) mouthwash compared to 0.12% chlorhexidine and placebo mouthwashes in individuals with gingivitis.
Materials and Methods: A randomized, double-blind, placebo-controlled clinical trial was conducted in 75 patients assigned equally to ECa 233, chlorhexidine, or placebo groups. Participants used the assigned …

Cost Analysis Of Integrated Genderaffirming And Sexual Health Services For Transgender Women In Thailand: Evidence From The Tangerine Clinic, Braprut Sawatwipachai, Kunncadah Anuwong, Nittaya Phanuphak, Rena Janamnuaysook, Kritima Samitpol, Sujin Nitadpakorn

The Thai Journal of Pharmaceutical Sciences

Background: Transgender women experience a disproportionate burden of human immunodeficiency virus (HIV) globally and in Thailand. Integrating gender-affirming care into sexual health services may improve uptake of HIV and sexually transmitted infections (STIs) testing, treatment, and prevention. Cost data are essential to inform program planning and policy decisions regarding inclusion of such services within Thailand’s Universal Health Coverage (UHC) system.
Objectives: To estimate the full and unit costs of trans-led, integrated gender-affirming and sexual health services along the HIV care cascade.
Methods: Costs of Tangerine Clinic services in 2021 were assessed from the provider perspective, using standard and activity-based costing …

Surgical And Transcatheter Pulmonary Valve Replacement In Patients With Congenital Heart Disease, Who Have A History Of Right Ventricular Outflow Tract Remodeling, Indonesia: A Model-Based Economic Evaluation, Andi Nurul Annisa, Puree Anantachoti, Radityo Prakoso, Dafsah A. Juzar, Osot Nerapusee

The Thai Journal of Pharmaceutical Sciences

Background: Patients with congenital heart disease who have previously undergone right ventricular outflow tract (RVOT) surgery frequently require repeat valve replacement later in life. While transcatheter pulmonary valve replacement (TPVR) offers less invasive reintervention compared with surgery, its high device cost raises concerns about affordability under Indonesia’s National Health Insurance Program (Jaminan Kesehatan Nasional).
Objectives: To compare the cost-effectiveness of surgical pulmonary valve replacement (SPVR) versus TPVR in post-RVOT surgery patients, and to estimate the TPVR price threshold for cost-effectiveness from a societal perspective.
Methods: A Markov model simulated a hypothetical cohort of 15-year-old patients with prior RVOT surgery over …

Anti-Diabetic Activity Of Combination Of Aloe Vera, Allium Sativum, Selenium, And Chromium Picolinate In Alloxaninduced Diabetic Rats, Satyajit Mangate, Syed Ayaz Ali, Zainab Shabbir Shaikh, Mohd Mukhtar Khan, Subur Wadood Khan

The Thai Journal of Pharmaceutical Sciences

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by deleterious effects on multiple organs. Existing remedial strategies highlight the advancement of herbal and mineral agents to target multiple mechanisms controlling the pathology of DM.
Objectives: This study aims to investigate the hypoglycemic and organ-protective effects of poly-herbal poly-mineral combinations for DM treatment.
Materials and Methods: Five groups of Wistar rats comprising 6 rats in each group were treated with vehicle (sterile water) to control group, alloxan (150 mg/kg, i.p.) to all the groups except the vehicle control group, sitagliptin (40 mg/kg, p.o.) as standard drug treatment, polyherbal polymineral combination …

Comparative Potency Testing Of Diphtheria Toxoid In Guinea Pigs And Mice For In-House Diphtheria-Tetanus-Pertussis And Diphtheria-Tetanus Vaccines, Wanlop Leeden, Supanee Ummalukacholk, Orawin Mangkhaladul, Eakachai Prompetchara

The Thai Journal of Pharmaceutical Sciences

Background: Diphtheria remains endemic in parts of Thailand and continues to threaten unvaccinated populations. To strengthen vaccine self-sufficiency, the Government Pharmaceutical Organization has developed in-house diphtheria–tetanus–pertussis (DTP) and diphtheria– tetanus (dT) vaccines. Potency testing of diphtheria toxoid is traditionally performed in guinea pigs; however, limitations in animal availability, cost, and logistics have prompted evaluation of alternative models.
Objectives: To compare diphtheria toxoid potency estimates of in-houseproduced DTP and dT vaccines using guinea pigs and mice, followed by a Vero cell-based toxin neutralization assay, and to assess the suitability of mice as an alternative model for potency testing.
Materials and Methods: …