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Articles 10561 - 10590 of 17394
Full-Text Articles in Entire DC Network
Quantitative Analysis Of “Tee Ka Tuk” Formulation Using Tlc-Densitometric Method, Maneekran Napakraw, Thitima Lhinhatrakool, Prasan Tanguenyongwatana
Quantitative Analysis Of “Tee Ka Tuk” Formulation Using Tlc-Densitometric Method, Maneekran Napakraw, Thitima Lhinhatrakool, Prasan Tanguenyongwatana
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Author Index, N/A
Floating And Mucoadhesive System Of Furosemide: Development And In Vitro Evaluation, Krunal Takarkhede, Dilesh Jagdish, Shagufta Khan, Pramod Yeole
Floating And Mucoadhesive System Of Furosemide: Development And In Vitro Evaluation, Krunal Takarkhede, Dilesh Jagdish, Shagufta Khan, Pramod Yeole
The Thai Journal of Pharmaceutical Sciences
Furosemide is poorly soluble in acidic pH and absorbed from the upper part of the Gl tract. We, therefore, aimed to develop a sustained release gastroretentive beads containing furosemide inclusion complex. The different formulations of floating beads we...
Influence Of Ephx1 Polymorphism And Clinical Factors On Carbamazepine Resistant Epilepsy, Khanistha Tuanthaisong, Yotin Chinvarun, Mayuree H. Tantisira, Pornpimol Kijsanayotin
Influence Of Ephx1 Polymorphism And Clinical Factors On Carbamazepine Resistant Epilepsy, Khanistha Tuanthaisong, Yotin Chinvarun, Mayuree H. Tantisira, Pornpimol Kijsanayotin
The Thai Journal of Pharmaceutical Sciences
The treatment outcomes of carbamazepine (CBZ) vary widely among patients. Single nucleotide polymorphisms (SNPs) in genes involved in pharmacokinetics and pharmacodynamics of CBZ may influence patients’ response to CBZ. We aimed to investigate the asso...
Simultaneous Spectrophotometric Determination Of Difloxacin And Enrofloxacin In Urine Samples By Partial Least Squares Regression (Pls) And Direct Orthogonal Signal Correction-Partial Least Squares Regression (Disc-Ols) Methods, Kuldeep Kaur, Ashok Kumar Malik, Baldev Singh, M. Godarzi
Simultaneous Spectrophotometric Determination Of Difloxacin And Enrofloxacin In Urine Samples By Partial Least Squares Regression (Pls) And Direct Orthogonal Signal Correction-Partial Least Squares Regression (Disc-Ols) Methods, Kuldeep Kaur, Ashok Kumar Malik, Baldev Singh, M. Godarzi
The Thai Journal of Pharmaceutical Sciences
Simultaneous determination of difloxacin and enrofloxacin using two chemometric methods, partial least squares regression (PLS) and direct orthogonal signal correction-partial least squares regression (DOSC-PLS) is described in this paper. The simultaneous determination of these drugs is difficult due to spectral interferences. The calibration graphs were linear in the range of 1-10 μg mL-1 and 1-9 μg mL-1 with detection limits of 0.52 and 0.15 μg mL-1 for difloxacin and enrofloxacin, respectively. The experimental calibration matrix was designed with 25 mixtures of these drugs. The PLS and DOSC-PLS were used for multivariate calibration of spectrophotometric data. The root mean square error …
Facile Derivative Uv Spectroscopy Method: Simultaneous Estimation Of Tinidazole And Fluconazole In Combined Tablet Dosage Form, Saurabh Pandey, Preeti Pandey, Shaifali Dubey, Udisha Chaturvedi, Awani K. Rai
Facile Derivative Uv Spectroscopy Method: Simultaneous Estimation Of Tinidazole And Fluconazole In Combined Tablet Dosage Form, Saurabh Pandey, Preeti Pandey, Shaifali Dubey, Udisha Chaturvedi, Awani K. Rai
The Thai Journal of Pharmaceutical Sciences
Two derivative spectrophotometric methods have been developed for simultaneous determination of tinidazole and fluconazole in pharmaceutical formulations. The first method depends on utilization of first derivative UV spectrophotometry, with zero-crossing and peak-to-base measurement at 260.57 & 264.23 nm for fluconazole and 263.86 & 318.85 nm for tinidazole. The second method, compensation technique depends on first derivative of the ratio-spectra by measurements of the amplitudes for tinidazole and fluconazole. Calibration graphs were established for tinidazole and fluconazole in the range of 10-100 μg ml-1 and 2-20 μg ml-1, respectively. All proposed methods have been extensively validated. The results were found to …
Simultaneous Estimation Of Cefixime And Cloxacillin In Human Plasma By Reversed Phase-Hplc With Uv Detection, Sommath D. Bhinge, Sharangouda M. Malipatil, Lalit V. Sonawane
Simultaneous Estimation Of Cefixime And Cloxacillin In Human Plasma By Reversed Phase-Hplc With Uv Detection, Sommath D. Bhinge, Sharangouda M. Malipatil, Lalit V. Sonawane
The Thai Journal of Pharmaceutical Sciences
An accurate, rapid and simple reversed-phase high performance liquid chromatography (RP-HPLC) method was developed and validated for simultaneous estimation of cefixime, cloxacillin and for chloramphenicol (internal standard) in human plasma. Chromatographic separation was accomplished using CAPCELL PAK C8 (4.6 mm Ó 250 mm, 5 μm) analytical column using phosphate buffer, methanol and acetonitrile (40:45:15) as eluent. Detection and quantification were performed by UV/Vis detection at 225 nm. The lower limit of detection and quantification were 0.01 μg†mL-1 and 0.25 μg†mL-1 for cefixime, 0.03 μg†mL-1 and 0.39 μg†mL-1 for cloxacillin. The calibration curves were linear over the concentration range 0.5 to …
Thrombolytic Activity Of Some Spices And Plants Available In Bangladesh, Md. Rakib Ai-Manun, Nabiha Amrin, Jahura Begum, Md. Abdul Mazid
Thrombolytic Activity Of Some Spices And Plants Available In Bangladesh, Md. Rakib Ai-Manun, Nabiha Amrin, Jahura Begum, Md. Abdul Mazid
The Thai Journal of Pharmaceutical Sciences
Thrombolytic activities of some plants, namely Tamarindus indica (Fabaceae), Flemingia congesta (Fabaceae), Lawsonia inermis (Lythraceae), Mesua nagassarium (Clusiaceae, and spices, namely Coriandrum sativum (Apiaceae), Curcuma longa (Zingiberaceae), Cinnamomum tamala (Lauraceae), Nigella sativa (Ranunculaceae), Eugenia aromaticum (Myrtaceae), available in Bangladesh, were evaluated using an in vitro model. The thrombolytic activity in terms of percentage of weight loss of in vitro formed clots were found as C. sativum 43.25 ± 7.18%, C. longa 53.32 ± 4.96%, C. tamala 22.10 ± 3.18%, N. sativa 28.49 ± 3.72%, E. aromaticum 32.18 ± 3.10%, T. indica 28.91 ± 2.29%, F. congesta 35.27 ± 7.35%, L. …
Lactobacillus Plantarum T23/3 As A Potential Probiotic Strain Isolated From Faces, Titpawan Nakpheng, Rosainee Kha, Neelam Balekar, Sanae Kaewnopparat, Teerapol Srichana
Lactobacillus Plantarum T23/3 As A Potential Probiotic Strain Isolated From Faces, Titpawan Nakpheng, Rosainee Kha, Neelam Balekar, Sanae Kaewnopparat, Teerapol Srichana
The Thai Journal of Pharmaceutical Sciences
The present study was undertaken to evaluate the properties of Lactobacillus plantarum T23/3 isolated from the feces of healthy elderly volunteer. The L. plantarum T23/3 showed better tolerance property to bile acid, simulated gastric fluid (SGF) and simulated intestinal fluid (SIF), and exhibited antimicrobial activity against tested enteropathogens. It formed macroscopic granules with surface hydrophobicity and co-aggregated with tested microbial strain. It was resistant to some antibiotics used for treatment of diarrhea so there is possibility to co-administer L. plantarum as probiotic with antidiarrheal therapy. Furthermore, adhesion and significant potential for decreasing adhesion of pathogens (E. coli 2601 and V. …
Application Of A Stability-Indicating Hptlc Method For Simultaneous Determination Of Chloramphenicol And Dexamethasone Sodium Phosphate In Eye Drop, Yimer Seid, Araya Hymete, Adnan A. Bekhit
Application Of A Stability-Indicating Hptlc Method For Simultaneous Determination Of Chloramphenicol And Dexamethasone Sodium Phosphate In Eye Drop, Yimer Seid, Araya Hymete, Adnan A. Bekhit
The Thai Journal of Pharmaceutical Sciences
A high performance thin layer chromatography (HPTLC) method was developed and validated for the simultaneous quantification of dexamethasone sodium phosphate and chloramphenicol in eye drop. The HPTLC separation was achieved on an aluminum-backed layer of silica gel 60F254 using acetonitrile: water: ammonia (10:3:0.5 v/v/v), pH adjusted to 7.8 with 1M HCl, as a mobile phase. The densitometric determination of dexamethasone phosphate and chloramphenicol was carried out at 262 nm. Calibration curves for dexamethasone phosphate and chloramphenicol were linear in the range of 80-300 ng and 400-1400 ng, respectively. The method was validated according to International Conference on Harmonization (ICH) guidelines …
Enhancement Of Wttability And In Vitro Dissoution Properties Of Lercanidipine Hydrochloride By Solid Dispersion Technique, Suneel Pandey, Ekunkumar Chandekar, Amarnath Wattamwar, Sachin Pandit, Hemant Joshee, Arun Patil
Enhancement Of Wttability And In Vitro Dissoution Properties Of Lercanidipine Hydrochloride By Solid Dispersion Technique, Suneel Pandey, Ekunkumar Chandekar, Amarnath Wattamwar, Sachin Pandit, Hemant Joshee, Arun Patil
The Thai Journal of Pharmaceutical Sciences
The aim of the present study was to improve lercanidipine HCl solubility and in vitro dissolution rate by preparing solid dispersion with polyethylene glycol (PEG) 6000 using the solvent evaporation technique. Solid dispersions with PEG 6000 (as carriers) were prepared in drug: carrier (1:1, 1:5 and 1:10) ratios along with the corresponding physical mixtures. Analytical techniques, FT-IR spectroscopy, differential scanning calorimetry (DSC) and X-ray diffraction (XRD) were used to characterize the drug in the physical mixtures and solid dispersions. The solubility and wettability studies of solid dispersions as well as physical mixtures showed greater improvement compared to the pure drug. …
ภาวะอักเสบกับผู้ป่วยที่เข้ารับการผ่าตัด, วัชริน สินธวานนท์
ภาวะอักเสบกับผู้ป่วยที่เข้ารับการผ่าตัด, วัชริน สินธวานนท์
Chulalongkorn Medical Journal
No abstract provided.
Acute Effects Of Aquatic Exercise On Trunk Flexibility And Low Back Muscle Strength In Healthy Thai Subjects, T Janyacharoen, S Sa-Nguanram, P Sarasuk, P Kaewlamul, L. Mato
Acute Effects Of Aquatic Exercise On Trunk Flexibility And Low Back Muscle Strength In Healthy Thai Subjects, T Janyacharoen, S Sa-Nguanram, P Sarasuk, P Kaewlamul, L. Mato
Chulalongkorn Medical Journal
Background : Aquatic exercise can increase the degree of movements of various joints, resulting in nimbleness and flexibility. Previous studies were carried out on long-term programs of aquatic exercise. There has not been any research work on acute effects of aquatic exercise. Objectives : To study the acute effects of aquatic exercise on the change of the trunk flexibility and strength of the lower back muscles of healthy subjects. Setting : Faculty of Associate Medical Sciences, Khon Kaen University. Design : Experimental research. Methodology : Ninety-eight healthy Thai persons who were divided into two groups: control and experimental. The control …
Preliminary Study Of Factors That Influence The Length Of Stays In Intensive Care Unit And Hospital After Open Heart Surgery With Cardiopulmonary Bypass At King Chulalongkorn Memorial Hospital, P Thaweechaiyapak, P Pulsawat, W. Sindhvananda
Preliminary Study Of Factors That Influence The Length Of Stays In Intensive Care Unit And Hospital After Open Heart Surgery With Cardiopulmonary Bypass At King Chulalongkorn Memorial Hospital, P Thaweechaiyapak, P Pulsawat, W. Sindhvananda
Chulalongkorn Medical Journal
Background : Factors indicated length of intensive care unit and hospital might be useful for improving ICU management. Objective : To identify factors that influence ICU and hospital stays after open heart surgery with cardiopulmonary bypass at King Chulalongkorn Memorial Hospital. Design : Retrospective descriptive study. Methods : Adult patients who underwent elective open heart surgery with cardiopulmonary bypass in 2009 were recruited population. Medical records were reviewed in terms of pre-operative conditions (patient characteristics, underlying diseases and laboratory data) and intraoperative events (type of operation, anesthetic technique, cardiopulmonary bypass time and aortic cross-clamp time). Multiple regressions were analyzed for …
Surgical And Anesthetic Managements Of An Adult Patient With A Giant Mediastinal Mass, W Sindhvananda, K. Luengtaviboon
Surgical And Anesthetic Managements Of An Adult Patient With A Giant Mediastinal Mass, W Sindhvananda, K. Luengtaviboon
Chulalongkorn Medical Journal
A 22-year-old male with a giant anterior mediastinal mass underwent general anesthesia and tumor removal through Clamshell incision. The mass (approximately 4 kg) that occupied the plural cavity with retarded venous drainage of the chest caused the symptoms and signs of SVC obstruction. Due to no sign of upper thoracic airway obstruction, the operation plan was not included CPB standby. Anesthesia in this case was difficult from the beginning. However, it was smoothed out with subsequent intravenous thiopental induction, followed by atracurium and sevoflurane in maintenance of the anesthesia. During the operation, accidental tear of the right atrium occurred; controls …
The Efficacy Of Dermal Extracted - Bone Powder Scaffold On The Healing Of Rat 'S Calvarial Bone Defects, A Hanworawong, T. Bunaprasert
The Efficacy Of Dermal Extracted - Bone Powder Scaffold On The Healing Of Rat 'S Calvarial Bone Defects, A Hanworawong, T. Bunaprasert
Chulalongkorn Medical Journal
Background : The bone substitute materials are expensive and imported. Objective : This study aimed to study the properties of the human dermalextracted solution mixed with bone powder shaped into scaffold on the healing of rat’s calvarial bone defects which are determined by radiopaque area in computed tomography (CT scan) and new bone formation in histological study. Design : Experimental study. Materials and Methods : Dermal-extracted solution, dermal-extracted solution mixed with bone powder, bovine collagen type I, and bovine collagen type I mixed with bone powder were structured into scaffolds and embedded into 24 female rats, aged between 12 - …
Skin Irritation Study Of Two Patented Mix Extracts From Emblica, Ma-Khwaen And Khanun, Sareeya Reungpatthanaphong, Tuanta Sematong, Buppachart Potduang, Phanukit Kunhachan, Cholticha Niwaspragrit
Skin Irritation Study Of Two Patented Mix Extracts From Emblica, Ma-Khwaen And Khanun, Sareeya Reungpatthanaphong, Tuanta Sematong, Buppachart Potduang, Phanukit Kunhachan, Cholticha Niwaspragrit
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Moisturizing Gel Formulation Containing Pueraria Mirifica Extracts As An Anti-Wrinkle Agent, Thanachod Thammachat, Sompoch Tubcharoen, Sitthiphong Soradech, Somnuk Promdang
Moisturizing Gel Formulation Containing Pueraria Mirifica Extracts As An Anti-Wrinkle Agent, Thanachod Thammachat, Sompoch Tubcharoen, Sitthiphong Soradech, Somnuk Promdang
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Quercetin And Derivatives As Butyrylcholinesterase Inhibitors, Siriluk Sontadsakul, Anchisa Prakongsantikul, Worawan Kitphati, Jaturong Pratuangdejkul, Veena Nukoolkam
Quercetin And Derivatives As Butyrylcholinesterase Inhibitors, Siriluk Sontadsakul, Anchisa Prakongsantikul, Worawan Kitphati, Jaturong Pratuangdejkul, Veena Nukoolkam
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Biological Activities Of A Patented Mix Extract From Fruits Of Phyllanthus Emblica And Zanthoxylumlimonella, Buppachart Potduang, Bundit Fungsin, Isara Keeta, Natthachest Ketmanee, Anintitha Intharungsri, Sitthiphong Soradech, Cholticha Niwaspragrit, Sayan Tanpanich
Biological Activities Of A Patented Mix Extract From Fruits Of Phyllanthus Emblica And Zanthoxylumlimonella, Buppachart Potduang, Bundit Fungsin, Isara Keeta, Natthachest Ketmanee, Anintitha Intharungsri, Sitthiphong Soradech, Cholticha Niwaspragrit, Sayan Tanpanich
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Anti-Periodontal Bacterial Activity Of Oxyresveratrol, Waranvoo Phoolcharoen, Sireerat Sooampon, Boonchoo Sritularak, Kittisak Likhitvitayawuid, Jintakom Kuvatanasuchati, Prasit Pavasant
Anti-Periodontal Bacterial Activity Of Oxyresveratrol, Waranvoo Phoolcharoen, Sireerat Sooampon, Boonchoo Sritularak, Kittisak Likhitvitayawuid, Jintakom Kuvatanasuchati, Prasit Pavasant
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Microemulsion Formulation Of Angelica Sinensis Root Extract On Clove Oil /Nonionic Surfactant/ Water Mixture, Pichaya Ukosaramik, Prasan Tangyuenyongwatana, Rathapon Asasutjarit
Microemulsion Formulation Of Angelica Sinensis Root Extract On Clove Oil /Nonionic Surfactant/ Water Mixture, Pichaya Ukosaramik, Prasan Tangyuenyongwatana, Rathapon Asasutjarit
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Factors Associated With 1-Year Mortality Of Patients Undergoing Coronary Artery Bypass Grafting At King Chulalongkorn Memorial Hospital, K Phisaiphun, O. Kyokong
Factors Associated With 1-Year Mortality Of Patients Undergoing Coronary Artery Bypass Grafting At King Chulalongkorn Memorial Hospital, K Phisaiphun, O. Kyokong
Chulalongkorn Medical Journal
Objective : This study was conducted to investigate predictors of mortality after isolated coronary artery bypass grafting (CABG). Design : Retrospective study Setting : King Chulalongkorn Memorial Hospital. Methods : Retrospective single-institutional data on risk factors and mortality were collected from 196 patients who underwent isolated CABG by the same group of surgeons from November 2007-October 2008. The relationship between risk factors and outcome was assessed using univariate and multivariate analyses. Results : The mean age of the patients (30.1% women and 69.9% men) was 61.1 +/- 9 years. Hypertension was the most common comorbidity factor (82.7%), followed by diabetes …
Validation Of Thai Version Of The Urogenital Distress Inventory And Incontinence Impact Questionnaires, T Manchana, S. Bunyavejchevin
Validation Of Thai Version Of The Urogenital Distress Inventory And Incontinence Impact Questionnaires, T Manchana, S. Bunyavejchevin
Chulalongkorn Medical Journal
Objective : To validate the Thai version of the Urogenital Distress Inventory (UDI) and Incontinence Impact Questionnaire (IIQ) for Thai women. Materials and Methods : The UDI and IIQ have been translated into Thai. Test - retest reliability and internal consistency were tested. Two hundred and eighteen patients who visited the urogynecologic clinic at King Chulalongkorn Memorial Hospital between March 2008 and April 2010 completed the Thai version of UDI and IIQ. A higher score indicates a greater impairment on the quality of life (QOL) but a lower score indicates a better QOL. Results : There were 86 asymptomatic and …
Esophageal Necrosis After Resection Of Descending Thoracic Aorta Aneurysm: A Case Of Successful Treatment, K Luengtaviboon, W. Sindhvananda
Esophageal Necrosis After Resection Of Descending Thoracic Aorta Aneurysm: A Case Of Successful Treatment, K Luengtaviboon, W. Sindhvananda
Chulalongkorn Medical Journal
Esophageal necrosis is a rare complication of treatment of the descending thoracic or thoraco-abdominal aortic aneurysm. It is almost always fatal. Sepsis and bleeding secondary to dehiscence of the aortic- graft suture line are main mechanisms of death. However, these patients can be saved by aggressive medical and surgical treatment. A 40-year-old male was transferred to this hospital because of severe epigastric pain secondary to concealed rupture of a descending aortic aneurysm. Urgent aneurysmectomy and bypass graft was done using "clamp-and-go technique". He was in septic conditions approximately a week later. An abscess around the graft was confirmed by CT …
Forensic Aspects Of Injuries Resulting From Cardiopulmonary Resuscitation, W. Charaschaisri
Forensic Aspects Of Injuries Resulting From Cardiopulmonary Resuscitation, W. Charaschaisri
Chulalongkorn Medical Journal
In 1960, Kouwenhoven observed that forceful compressions on the chest could produce an arterial pulse. Over the following years, cardiopulmonary resuscitation (CPR) became continuously advanced. Currently, experts at the conference on International Guidelines 2010 strongly recommend development of in-school CPR programs as a primary educational strategy to ensure wide-spread learning of CPR. During CPR the physician always gives priority to dealing with the life-threatening condition first. While CPR can save lives, it may also expose a high risk of injury to the patient. As a result, forensic pathologists often find CPR-related injuries during autopsies that are unrelated to the patients' …
Identification Of Forensically Important Blowflies In Thailand Based On The Second Internal Transcribed Spacer Region Of Ribosomal Dna And The Nadh Dehydrogenase Subunit 5 Gene, R Jantorn, P Siriyasatien, A Tawatsin, U Thavara, K. Preativatanyou
Identification Of Forensically Important Blowflies In Thailand Based On The Second Internal Transcribed Spacer Region Of Ribosomal Dna And The Nadh Dehydrogenase Subunit 5 Gene, R Jantorn, P Siriyasatien, A Tawatsin, U Thavara, K. Preativatanyou
Chulalongkorn Medical Journal
Problem/Background: Estimation of postmortem interval (PMI) is essential for supporting justice especially in legal cases. At early stage of death, the PMI can be evaluated using data from physical changes of the corpses. In case of the corpses that have died more than 48 hours, the physical change may be less accurate for prediction. The species identification of blowflies, early found on corpses, as well as the specific developmental stage are required for PMI estimation. However, it is not yet practical for morphological identification. To surpass these problems, DNAbased identification is preferentially applied.
Effects Of Mental Health Promotion Program On Mathayom 5 Students Of Triam Udom Suksa School, S Petkum, N. Pityarstian
Effects Of Mental Health Promotion Program On Mathayom 5 Students Of Triam Udom Suksa School, S Petkum, N. Pityarstian
Chulalongkorn Medical Journal
Objective : To study the effect of mental health promotion program on Mathayom 5 students of Triam Udom Suksa School. Design : This is an experimental research: before-after-experimental with one control group that will also receive mental health promotion programs after the completion of the trial. Setting : Mathayom 5 (Grade5) students of Triam Udom Suksa School, Phaya Thai, Bangkok, academic year 2552 (AD 2009). Materials and Methods : This research is aimed to study the effect of mental health promotion program on Mathayom 5 (Grade5) students. Tools used in this study were divided into 3 parts: 1) Questionnaire of …
The Effect Of N-Trans-P-Coumaroyl Tyramine On Indomethacin-/Diclofenac-Mediated-Cytotoxicity In Breast Cancer Cells., Angkana Wongsakul
The Effect Of N-Trans-P-Coumaroyl Tyramine On Indomethacin-/Diclofenac-Mediated-Cytotoxicity In Breast Cancer Cells., Angkana Wongsakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Indomethacin (INDO) and diclofenac (DIC) are non-steroidal anti-inflammatory (NSAIDs) have been reported their anticancer potential. Their cytotoxicity could be increased when combining with certain natural compounds such as piperine in Piper plants. N-trans-p-coumaroyltyramine (TCT) (a coumaric acid derivative) was also found at significant amount in these plants and other commonly used in traditional medicine. This study determined the potentiative effect of TCT on NSAIDs (INDO and DIC) induced cytotoxicity in MCF-7 breast cancer cells, and the underlying mechanisms. Combination of TCT with either NSAIDs or various ER stressors at their non-cytotoxic concentrations were able to reduce cell viability in MCF-7 …
Toxicity Test Of Kameng (Eclipta Prostrate Linn.) And Kradhuawean (Spilanthes Acmella (Linn.) Murr.) To Early Life Stage Of Zebrafish (Danio Rerio) Aranya, Aranya Ponpornpisit, Nopadon Pirarat, Wanwipa Suthikrai, Anong Binwihok
Toxicity Test Of Kameng (Eclipta Prostrate Linn.) And Kradhuawean (Spilanthes Acmella (Linn.) Murr.) To Early Life Stage Of Zebrafish (Danio Rerio) Aranya, Aranya Ponpornpisit, Nopadon Pirarat, Wanwipa Suthikrai, Anong Binwihok
The Thai Journal of Veterinary Medicine
The toxicity of Kameng (Eclipta prostrate Linn.) and Kradhuawean (Spilanthes acmella (Linn.) Murr.) onzebrafish (Danio rerio) embryos was investigated. An aqueous crude extract of the leaves of each plant was tested withnewly spawned embryos in 96 well plates. The observed effect was based on the toxicity endpoint composed of lethal,sublethal and malformation effects appearing at 24, 48 and 144 hours post-fertilization (hpf). The results suggest thatthe lowest observed effect concentrations (LOEC) for a lethal and sublethal effect of Eclipta prostrate Linn. at 48 hpfwere 1% and 0.1% while the no observed effect concentrations (NOEC) for the lethal and sublethal effects …