Digital Commons Network^™

Thyroid Hormone Regulation Of Mrnas Encoding Thyrotropin Β-Subunit, Glycoprotein Α-Subunit, And Thyroid Hormone Receptors Α And Β In Brain, Pituitary Gland, Liver, And Gonads Of An Adult Teleost, Pimephales Promelas, Sean C. Lema, Jon T. Dickey, Irvin R. Schultz, Penny Swanson

Biological Sciences

Thyroid hormones (THs) regulate growth, morphological development, and migratory behaviors in teleost fish, yet little is known about the transcriptional dynamics of gene targets for THs in these taxa. Here, we characterized TH regulation of mRNAs encoding thyrotropin subunits and thyroid hormone receptors (TRs) in an adult teleost fish model, the fathead minnow (Pimephales promelas). Breeding pairs of adult minnows were fed diets containing 3,5, 3^,-triiodo-_L-thyronine (T₃) or the goitrogen methimazole for 10 days. In males and females, dietary intake of exogenous T₃ elevated circulating total T₃, while methimazole …

Theoretical Analysis Of Alendronate And Risedronate Effects On Canine Vertebral Remodeling And Microdamage, Xiang Wang, Antonia M. Erickson, Matthew R. Allen, David B. Burr, R. Bruce Martin, Scott J. Hazelwood

Biomedical Engineering

Bisphosphonates suppress bone remodeling activity, increase bone volume, and significantly reduce fracture risk in individuals with osteoporosis and other metabolic bone diseases. The objectives of the current study were to develop a mathematical model that simulates control and 1 year experimental results following bisphosphonate treatment (alendronate or risedronate) in the canine fourth lumbar vertebral body, validate the model by comparing simulation predictions to 3 year experimental results, and then use the model to predict potential long term effects of bisphosphonates on remodeling and microdamage accumulation. To investigate the effects of bisphosphonates on bone volume and microdamage, a mechanistic biological model …

Incremental Validation Of Formal Specifications, Paul S. Corwin

Master's Theses

This thesis presents a tool for the mechanical validation of formal software specifications. The tool is based on a novel approach to incremental validation. In this approach, small-scale aspects of a specification are validated, as part of the stepwise refinement of a formal model.

The incremental validation technique can be considered a form of "lightweight" model checking. This is in contrast to a "heavyweight" approach, wherein an entire large-scale model is validated en masse.

The validation tool is part of a formal modeling and specification language (FMSL), used in software engineering instruction. A lightweight, incremental approach to validation is beneficial …

Agricultural Buffer Criteria For The City Of Arroyo Grande, Laura A. Pennebaker

Master's Theses

The conservation of agricultural land is an important and challenging part of local and regional planning. Prime agricultural soils and viable agricultural operations serve as a vital part of California’s identity and economy. The conversion of land from farming to non-agricultural use significantly increases the potential for conflict between adjoining land uses and intensifies the pressure to develop adjacent farmland. Agricultural buffers serve as a tool to mitigate potential conflict between adjacent non-compatible land uses and protect both farming operations and residents from nuisance complaints. The City of Arroyo Grande has agricultural buffer policies which apply to development taking place …

Evaluation Of Herbicide Efficacy As Influenced By Adjuvant And Nozzle Type, Catherine L. (Grissom) Ansolabehere

Master's Theses

White clover (Trifolium repens) is a common and difficult weed to control in turfgrass as it is a highly visible and unsightly weed that disrupts the uniformity of the turfgrass surface. This weed is a serious problem in the turfgrass industry in California and there is a need for better methods of control. With more regulations on pesticides and less information about efficient application techniques, controlling white clover with available herbicides can be difficult.

Compatibility trials were conducted during the summer of 2005 to determine the compatibility of the herbicides and adjuvants planned for use in subsequent greenhouse and field …

Development Of An In-Vitro Tissue Engineered Blood Vessel Mimic Using Human Large Vessel Cell Sources, Dimitri E. Delagrammaticas

Master's Theses

Tissue engineering is an emerging field that offers novel and unmatched potential medical therapies and treatments. While the vast aim of tissue engineering endeavors is to provide clinically implantable constructs, secondary applications have been developed to utilize tissue-engineered constructs for in-vitro evaluation of devices and therapies. Specifically, in-vitro blood vessel mimics (BVM) have been developed to create a bench-top blood vessel model using human cells that can be used to test and evaluate vascular disease treatments and intravascular devices. Previous BVM work has used fat derived human microvascular endothelial cells (EC) sodded on an ePTFE scaffold. To create a more …

Implementation Of Physiologic Flow Conditions In A Blood Vessel Mimic Bioreactor System For The Evaluation Of Intravascular Devices, Marc Cody Dawson

Master's Theses

The prevalence and devastating nature of cardiovascular diseases has led to many advancements in the therapies used to treat the millions of patients that suffer as a result of these conditions. As coronary artery disease (CAD) is the most common of these cardiovascular conditions, it is a major focus of research among the medical industry. Although lifestyle changes and drug therapies can treat early CAD, more advanced cases often require more definitive interventions. In conjunction with angioplasty, stenting of an occluded vessel has shown significant success in preventing restenosis. However, as with nearly every therapeutic process in the medical field, …

Mustang Daily, April 30, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Executive Committee - Agenda, 4/28/2009, Academic Senate

Academic Senate Agendas

No abstract provided.

Mustang Daily, April 27, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Mustang Daily, April 24, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

April 22, 2009 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Mustang Daily, April 22, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Dynamics Simulation And Malfunction Diagnosis Of Heavy Machinery Using Msc Adams, Dewen Kong, Jim M. Meagher, Xi Wu

Mechanical Engineering

No abstract provided.

Mustang Daily, April 20, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Mustang Daily, April 17, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Mustang Daily, April 16, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Mustang Daily, April 15, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Executive Committee - Agenda, 4/7/2009, Academic Senate

Academic Senate Agendas

No abstract provided.

Passings: Prominent Orange County Developer, Cal Poly Benefactor Richard J. O'Neill, Public Affairs Office

Press Releases

No abstract provided.

Cal Poly Students Lend A Hand In New Orleans Over Spring Break, Public Affairs Office

Press Releases

No abstract provided.

Culturally Speaking: Raw Milk Quality, Phillip S, Tong

Dairy Science

No abstract provided.

Engineering Advantage, Spring 2009, College Of Engineering

Engineering Advantage

No abstract provided.

Cal Poly Magazine, Spring 2009

Cal Poly Magazine

No abstract provided.

Focus: Journal Of The City And Regional Planning Department, Volume 6

Focus

No abstract provided.

Growth Hormone Alters The Proteome Of Differentiated Mac-T Cells, Tasha Lynn Johnson, Daniel G. Peterson

Animal Science

Growth Hormone (GH) improves growth and lactation in many species. Mammary epithelium is responsive to GH though the mechanism of these effects has not yet been fully characterized. Bovine Mammary Alveolar Cell-T (MAC-T) cells uniformly differentiate and secrete casein proteins in response to dexamethasone, insulin and prolactin (DIP) and are a widely used ruminant mammary cell model. We have found significant changes in triacyglycerol, cholesterol and phospholipid distribution in MAC -T cells stimulated with 10 ng/ml GH. To characterize these direct effects of GH on a proteomic level, total protein was isolated from MAC-T cells after differentiation for seven days …

A Mean, Green Energy Machine, Mary Mcnally

Cal Poly Magazine

No abstract provided.

A Trans-Holocene Archaeological Record Of Guadalupe Fur Seals (Arctocephalus Townsendi) On The California Coast, Torben C. Rick, Robert L. Delong, Jon M. Erlandson, Todd J. Braje, Terry L. Jones, Douglas J. Kennett, Thomas A. Wake, Phillip L. Walker

Social Sciences

No abstract provided.

Agriview, Spring 2009, College Of Agriculture, Food, And Environmental Sciences: California Polytechnic University - San Luis Obispo

AGRIVIEW

No abstract provided.

The Benefit Of Foliar Applied Copper Fertilizer On Romaine Lettuce Grown In Low Copper Soils Of The Coastal Santa Maria, California, Emmy R. Williams

Master's Theses

The importance of trace elements nutrients to vegetable crops has received more attention in recent years. Accordingly this experiment investigated the benefit of foliar applied copper fertilizer on romaine lettuce (Lactuca Sativa Longifolia) grown in low soil Copper (Cu) concentration in the coastal Santa Maria, California. The various rates of Cu fertilizer applied include untreated (control), 100, 200, 400 and 800 grams per acre of CuSO4.5H 2O, using a one time and a split application methods. Three consecutive individual experimental fields were established starting in late spring through the fall of 2008. The soil texture was a loam in all …