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Scanning Electron Microscopy And Histology Imaging And Analysis Of Decellularized Porcine Vessel, Evans Moc, Jimmy Thai

Biomedical Engineering

No abstract provided.

Esem Analysis Of Mice Femurs With Varying Sost Levels, Patrick K. Mcclay

Biomedical Engineering

This project’s goal was to analyze the properties of the cortical femur on 100 mice bones from Lawrence Livermore National Laboratory. Analysis was limited to imaging which determined the ratio of bone volume to total volume (BV/TV) and osteocyte lacunae density. Mice were altered to knock out their SOST gene: a negative regulator of bone formation. Twelve groups were created to differentiate their treatment, duration, and phenotype. Transgenic (TG) mice had an overexpression of the SOST gene: they carried a bacterial artificial chromosome. Mice with limb defects (DEF) were the offspring of two TG mice and carried twice the amount …

Sustainable Agriculture, Charlene Mills

Social Sciences

This paper is about sustainable agriculture and how we can strive to achieve it. It discusses what is wrong with our food system today and how we can go about changing that. It incorporates Geography and Anthropology while discussing different issues around the world.

The Invasion Of California Grasslands: Past, Present, And Future Implications, Danielle Simone Caziarc

Social Sciences

No abstract provided.

Yoga Swell: A Stepping Stone Toward The Promotion Of Personal Revolution, Heather Wicks

Communication Studies

No abstract provided.

Corrosion Of Stainless Steel 316l And Astm F75 Cobalt Chromium Alloy During Immersion Testing In Silver Salt Solutions, Meagan Higgins

Materials Engineering

This study evaluates the potential effects of silver salts on biocompatible metals used for prostheses during the chemical reduction process to produce a silver antimicrobial layer on the metal’s surface. Samples of two biocompatible metals were obtained: Stainless Steel 316L and ASTM F75 Cobalt Chromium Alloy. Three different silver salts were also acquired: silver nitrate, silver sulfadiazine, and silver chloride. Specimens of each metal were cut to size using a 4-1/2 inch aluminum oxide, 40 grit, cut off wheel for metal, attached to a Dewalt Angle Grinder. The biocompatible metal samples were then subject to either Solution 1, water with …

An Analysis Of Coastal Marine Impacts Caused By Prehistoric And Historic Fishing Practices In Morro Bay, Ca, Darin Schmicking

Social Sciences

No abstract provided.

Reducing The Enviromental Impact Of Horse Keeping, Amanda R. Shere

Social Sciences

No abstract provided.

Articulating Sexuality: A Critical History Of Gay And Lesbian Anthropology, Carly Fox

Social Sciences

The purpose of this paper is to explore anthropological discourses regarding sexuality and relate them to the lived experiences of individuals. The paper is divided into two interrelated sections: historical and theoretical. Section one identifies a subfield within anthropology, gay and lesbian anthropology, most prominently represented by The Society of Lesbian and Gay Anthropologists (SOLGA), and traces its emergence within the wider discipline of anthropology. It highlights the foundational scholars and theoretical shifts that have been crucial in defining the subfield as it is today and looks at how early anthropologists approached sexuality in general, and same- sex sexuality in …

The Effects Of Concentration, Stir Rate, And Processing Temperature On The Iridescence Of Polymethyl Methacrylate Nanoparticles, David Baruela

Materials Engineering

Synthetic opals were synthesized by creating polymethyl methacrylate (PMMA) nanospheres in order to determine which conditions would create the best iridescent samples. The factors affecting the iridescence were nanosphere concentration, stir rate, and processing temperature. PMMA solutions were made by adding 17 mg of granular azobis to a solution of 16 mL of distilled water with 3 mL of methyl methacrylate (MMA). The solution was stirred at different rates, slow and fast, and different temperatures, 70 °C and 90 °C, under a constant flow of nitrogen gas for 40 minutes until the polymerization reaction was complete. Glass substrates were prepared …

Wine Tasting Through Typography, Dayna Goldman

Graphic Communication

The purpose of this study is to find the connection, if any, between the design and typography of wine labels with the flavor attributes of the wine itself. If there is a lacking connection, wineries can use this information to better market their wines so that consumers know more about the wines they are purchasing and can make a more informed decision. This allows these wineries to better market themselves and differentiate from their competitors.

The research focuses mainly on smaller, local wineries because these are the businesses that need more assistance or direction in creating and marketing their brand. …

The Role Of Html5 And Flash In Web Design, Kaela Soohoo

Graphic Communication

The purpose of this study was to determine whether HTML5 will replace Flash in the web design industry. Using the information taken from the study, the researcher made a prediction to answer the former question.

The researcher looked further into these programs and find information to determine what it is that makes each of these programs unique and possibly replaceable. The researcher also interviewed and surveyed those who used these programs to design or view online websites to gain insight on practicality and current trends in the web design industry.

Through research and experimentation, the researcher decided that HTML5 may …

Preserving Wildlife In San Luis Obispo City By Way Of San Luis Obispo Creek, Sydni Nicolici

Liberal Arts and Engineering Studies

The effectiveness of San Luis Obispo wildlife easements and city open space utilized to preserve species of concern is correlated to the health and maintenance of the San Luis Obispo Creek. I propose that the health of the Creek be addressed before more open space is added to the green belt surrounding the city. This bottom-up approach to preservation will ensure all steps of habitat will function as they should.

San Luis Obispo Entrepreneur's Market: Translating The Successful Aspects Of Slo's Farmer's Market Into A Model For A Talent Marketplace, Emily Swift

Liberal Arts and Engineering Studies

Details design elements of a physical space created for the purpose of economic and community development, where the guiding principles of design enable self-organizing sustainable systems for developing commerce, enterprise, business, and talent to work streams. The primary assumption is that if individuals in the community know their talent and are able to connect that talent to work with passion, meaning, and purpose, the community will thrive.

Small-Scale Solar Central Receiver System Design And Analysis, Daniel Murray

Master's Theses

This thesis develops an analytical model of a small-scale solar central receiver power plant located at the California Polytechnic State University in San Luis Obispo, California at 35.28° N, 120.66° W. The model is used to analyze typical energy output at any time during the year. The power plant is designed to produce an output of 100 kW electrical power, and is supplemented by the combustion of natural gas. Methodologies for determining the proper size and layout of heliostats, optimal tower height, receiver size, and turbine engine selection are developed. In this specific design, solar shares of up to 73.2% …

Growing Gardens: Botanical Gardens, Public Space And Conservation, Terra Celeste Colburn

Master's Theses

This thesis examines the history of botanical gardens and their evolution

from ancient spaces to the modern gardens of the 20th century. I provide a brief

overview of botanical gardens, with a focus on the unique intersection of public

participation and scientific study that started to occur within garden spaces during

the 20th century, which still continues today. I reveal the history of gardens that

influenced the uses of gardens today, with a focus on: the first ancient gardens

and the dependency societies had on them, the influence of science in gardens

starting in the Enlightenment period, the shift away …

Application Of A Heuristic Method To A Water Distribution System For Determining Optimal Water Quality Monitoring Locations, Lawrence David Johnson

Master's Theses

Although regulations and requirements for water quality source monitoring have increased, drinking water distribution systems can still be considered vulnerable to purposeful or accidental contamination.

This study analyzes the transport of the hypothetical contaminant Cryptosporidium through the distribution system of a city with a population of 30,000 to 50,000 in an attempt to locate the optimal monitoring locations in the distribution system. Cryptosporidium was selected due to its resistance to chlorine and it’s conservative properties for vulnerability assessments. The method for selecting the optimal monitoring locations was taken from Chastain (2004) which developed and examined the method for a virtual …

Hapss, Hybrid Aircraft Propulsion System Synthesis, Michael W. Green

Master's Theses

Hybrid Aircraft Propulsion System Synthesis (HAPSS) is a computer program that sizes and analyzes pure-series hybrid electric propulsion systems for aircraft. The development of this program began during a NASA SBIR contract, in conjunction with Empirical Systems Aerospace (ESAero), with the creation of a propulsion fan design tool. Since the completion of this contract in July 2010, the HAPSS program has been expanded to combine the many aspects of a hybrid propulsion system such as the propulsive fans, electric motors, generators, and controllers, and the internal combustion engines.

This thesis describes the benefits and drawbacks of aircraft hybrid propulsion systems …

Preparation And Characterization Of Electrospun Poly(D, L-Lactide-Co-Glycolide) Scaffolds For Vascular Tissue Engineering And The Advancement Of An In Vitro Blood Brain Barrier Model, Deven Chandrakant Patel

Master's Theses

Developing an in vitro Blood Brain Barrier model that will replicate the physiological, anatomical, and functional characteristics of the native BBB has gained significant attention. Such a model would enable prediction of the penetration of CNS targeting drug candidates across the BBB, allow pre-screening and optimization strategies to be developed for new drugs and gene delivery formulations, and permit research groups to further understand how a dysfunctional BBB is involved in the pathogenesis of several neurological diseases.

The Tissue Engineering laboratory at the California Polytechnic State University, San Luis Obispo is currently in the process of developing a dynamic in …

A Proteomic Analysis Of Differentiation In The Mammary Epithelium, Laura Therese Strand

Master's Theses

While a great deal is known about the changing hormonal environment and the structural development of the mammary gland from pregnancy to lactation, very little is known about the molecular mechanisms governing differentiation of the mammary epithelium into a milk-secreting phenotype. It is important to acknowledge the diversity among the mammary glands of different species in order to better understand applications in human health and the dairy industry. In this study, we examined global protein expression during two states of differentiation in mammary epithelial cells from two species: in vitro proliferating and differentiated MAC-T cells (a bovine immortal cell-line), and …

Seasonal Food Habits Of Burrowing Owls (Athene Cunicularia) In Human-Altered Landscapes, Carie Marie Wingert

Master's Theses

In 2004, I initiated a year-long study to investigate the food habits of burrowing owls (Athene cunicularia). Burrowing owls have been found in a variety of human-altered landscapes; however, little is known about burrowing owl food habits in urban landscapes. Burrowing owl food habits during the non-breeding season are also largely undocumented, despite increasing concern over the survival of overwintering burrowing owls. Differences in prey consumption between reproductive and non-reproductive owls during the breeding season have not yet been examined. I collected pellets over a 12 month period at four study sites affected by different levels of human …

Effects Of Ovariectomy, Seasonal Changes, And Anatomical Position On The Compact Bone Remodeling As Seen In The Adult Ovine Model, Erica Wong

Master's Theses

The purpose of this study is to characterize the compact bone remodeling of the ovariectomized ewe and its effectiveness as an animal model for studies of postmenopausal osteoporosis. The use of animal models is a beneficial way to evaluate the effectiveness of medical devices and therapeutic agents for treating diseases. The ovine model is an attractive option because of its large size and similar bone remodeling to humans. However, this species, like most animals, does not undergo a natural menopause, making an ovariectomy necessary for studies of estrogen depletion. The OVX (ovariectomized) sheep has been widely accepted as a model …

Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham

Biomedical Engineering

No abstract provided.

Development Of A Blood Flow Measurement Protocol Using Particle Image Velocimetry, Jennifer Chi-Ying Go

Biomedical Engineering

Peripheral Arterial Occlusive Disease (PAOD) is an acquired inflammatory disease where a peripheral artery becomes occluded due to the buildup of atherosclerotic plaques. In patients that possess collateral arteries, an occlusion can lead to shear induced outward remodeling, arteriogenesis, of these collaterals, partially restoring blood flow. However, newly remodeled collaterals exhibit reduced functional vasodilation, which may impair normal activity, such as ambulation. To model chronic ischemia and arteriogenesis in collaterals, a femoral artery ligation in a murine hindlimb is commonly performed. Previous efforts by our group involved measurements of collateral artery diameter to assess the impact of arteriogenesis on functional …

Development And Characterization Of Plga And Eptfe Blood Vessel Mimics Using Gene Expression Analysis, Michael Gibbons, Sarah Ur

Biomedical Engineering

Tissue engineered blood vessels (TEBV’s) have the potential to act not only as a replacement for diseased vessels, but also as a testing platform for intravascular devices such as stents. To this end, the goal of this study was to develop protocols for the construction of TEBV’s composed of human vascular cells and either expanded polytetrafluoroethylene (ePTFE) or poly-lactic-co-glycolic acid (PLGA), as well as a protocol for gene expression in those TEBV’s. Initial experiments involved only human umbilical vein endothelial cells (HUVEC’s), but after low cell confluency and spreading in single-sodded vessels a second cell type, human umbilical vein smooth …

May 30, 2012 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Approaches To Control Nitrate Pollution In The San Joaquin Watershed, Misgana K. Muleta, Stephen Clayton

Civil and Environmental Engineering

No abstract provided.

Approaches To Control Nitrate Pollution In The San Joaquin Watershed, Misgana K. Muleta, Stephen Clayton

Physics

Modeling of the San Joaquin valley using SWAT can give a comprehensive overview of hydrologic traits of the San Joaquin River and its tributaries, specifically for nutrients like nitrate. The San Joaquin valley is a site of intense modeling interest and policy making, as the San Joaquin River joins the Sacramento River to feed into the Delta. The environmental impact of dissolved oxygen on aquatic life on the Delta is a particularly key concern (Quinn 2000). The San Joaquin watershed also represents considerable investment in agriculture on the valley floor and has been studied for nitrate, sediment, and salinity concerns …

Executive Committee - Agenda, 5/15/2012, Academic Senate

Academic Senate Agendas

No abstract provided.

Formulating The Next Generation Of Cultured Dairy Foods, Phillip S. Tong

Dairy Science

No abstract provided.