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Differential Binding Of Host Cell Proteins By Vpr Mutant R77q Compared With Wild Type Vpr, Madison C. Wagley Apr 2025

Differential Binding Of Host Cell Proteins By Vpr Mutant R77q Compared With Wild Type Vpr, Madison C. Wagley

Theses and Dissertations

HIV Viral protein R (Vpr) is a multifunctional accessory protein which plays a role in nuclear import of the pre-integration complex, transactivation of HIV LTR promoter, cell cycle arrest, and apoptosis during HIV infection. R77Q is an HIV Vpr mutant which is associated with long-term non-progressor phenotypes, and which has previously been connected to higher levels of apoptosis compared to wild type Vpr in vitro. There are observable differences in host binding partners with HIV Vpr between wild type and R77Q strains as shown via coimmunoprecipitation and mass spectrometry. In one run R77Q samples showed binding to histone 1.2, 1.3, …

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A Novel Approach To Detect Shapes Of Constant Width, Ian D. Monk Apr 2025

A Novel Approach To Detect Shapes Of Constant Width, Ian D. Monk

Theses and Dissertations

Bodies of constant width have been studied mathematically since Euler and have found various applications in engineering and other areas. In this paper, we seek to develop novel tools to gain deeper insights into these shapes and to better be able to analyze them. The idea which motivates the development in this paper is as follows: a body has constant width if and only if the chord connecting the intersections of the boundary of the body with each pair of parallel hyper planes which lie tangent to a body lies perpendicular to the hyper planes.This is a known fact and …

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Development Of Raman Spectroscopic Methods To Analyze Chemical, Biological, And Physical Constituents For Food Safety And Quality, Hannah C. Broadbent Apr 2025

Development Of Raman Spectroscopic Methods To Analyze Chemical, Biological, And Physical Constituents For Food Safety And Quality, Hannah C. Broadbent

Theses and Dissertations

Ensuring food safety and quality is crucial for consumer health, satisfaction, and regulatory compliance. This study aims to develop rapid, reliable methods for detecting food constituents (i.e. lactose), pathogens (i.e. Listeria monocytogenes), and contaminants (i.e. micro- and nano-plastics) using Raman spectroscopy. With advantages like high specificity, minimal sample preparation, and fast analysis, Raman spectroscopy offers a promising alternative to traditional methods. This research explores its application in assessing chemical, biological, and physical properties of food to enhance safety and quality monitoring. Lactose-free products are increasingly popular due to the global prevalence of lactose intolerance, creating a need for effective verification …

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Partial Replication Of The Severe Outcome Questionnaire (S-Oq): Determining Benchmarks Using Ecologically Valid Data, Joshua J. Allen Apr 2025

Partial Replication Of The Severe Outcome Questionnaire (S-Oq): Determining Benchmarks Using Ecologically Valid Data, Joshua J. Allen

Theses and Dissertations

Background: The Severe Outcome Questionnaire (S-OQ) is a self-report tool whose most recent manual was published in 2008. It measures the treatment progress of the seriously mentally ill (SMI). Objective: 1). Partially replicate the outpatient and inpatient admission, change, and internal consistency data. 2). Provide a manual extension including admission and change data for new settings of care and include treatment modality benchmarks. Method: OQ Measures provided an archival data set drawn from six different community mental health organizations from around the United States covering 101 different clinics (N = 25,511; Male = 11,524, Female = 13,987). We constructed normative …

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Frost Heave Of Clayey Soils Treated With Cement Or Lime, Ammon K. Hymas Apr 2025

Frost Heave Of Clayey Soils Treated With Cement Or Lime, Ammon K. Hymas

Theses and Dissertations

The objective of this research was to measure and compare the effects of portland cement and lime at low, medium, and high concentrations on the frost-heave susceptibility of multiple clayey soils with varying plasticity indices. The scope of work included laboratory frost-heave testing of three clayey soils sampled from Monticello, Utah; Bloomington, Indiana; and San Antonio, Texas. Each soil was tested with two stabilizers, cement or lime, at three concentrations, as well as with no treatment. Two replicate samples were prepared for each combination, for a total of 42 specimens. The frost-heave testing procedures for this research involved preparing specimen …

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Hydrologic Decision Support In The Nile Basin: Creating Status And Outlook Products From The Geoglows Hydrologic Model, Rachel Huber Apr 2025

Hydrologic Decision Support In The Nile Basin: Creating Status And Outlook Products From The Geoglows Hydrologic Model, Rachel Huber

Theses and Dissertations

Decision makers and stakeholders need information about current and future streamflow to make informed decisions and we show how the GEOGLOWS Hydrologic Model, known as River Forecast System (RFS), can be used to provide hydrologic status and outlook products to inform these decisions. We examine a specific use case of RFS in the Nile River Basin and how RFS is used to provide users with hydrologic status products. We work with stakeholders at the Nile Basin Initiative to assess their needs for this information. We use basic low flow calculations to compute the Standardized Streamflow Index (SSI) and the 95th …

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Human Passion In The City And The Jungle: Translating Horacio Quiroga’S “Dieta De Amor,” “El Simún,” And “Polea Loca”, Washington C. Pearce Apr 2025

Human Passion In The City And The Jungle: Translating Horacio Quiroga’S “Dieta De Amor,” “El Simún,” And “Polea Loca”, Washington C. Pearce

Theses and Dissertations

Horacio Quiroga, Uruguayan-Argentine writer who is often considered analogous to Edgar Allan Poe, is notable for his contributions to the development of South American Modernismo and his status as a precursor to the Latin American "Boom" period. My project presents a translation of three previously untranslated short stories: "Dieta de Amor," "El Simún," and "Polea Loca." As a preface to these translations I articulate my translation theory and give examples of that theory in practice. I draw upon Jorge Luis Borges, Lawrence Venuti, and Friedrich Schleiermacher as translation scholars who have influenced my work.

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Systematic Analysis On The Applications Of Infrastructure Asset Management In Utah, Kelvin Kozakevitch Apr 2025

Systematic Analysis On The Applications Of Infrastructure Asset Management In Utah, Kelvin Kozakevitch

Theses and Dissertations

Public infrastructure is essential to a region’s economic stability and quality of life, especially its rural infrastructure where most consumable and essential goods derive from. Given the high capital investment required for infrastructure development and maintenance, asset management plans (IAM) are critical. Even though academic research exists on the problems rural infrastructure management face, little is known about the actual state, barriers and causes for the challenges IAM faces in rural Utah. This study examines the current challenges and barriers in IAM among rural communities in Utah. Employing a grounded theory approach, data was collected through a two-phase methodology: phase …

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"Peace [That] Could Only Be Amazement, Too": Narrativizing Wonder And Strangeness In Marilynne Robinson's Lila, Tricia Cope Apr 2025

"Peace [That] Could Only Be Amazement, Too": Narrativizing Wonder And Strangeness In Marilynne Robinson's Lila, Tricia Cope

Theses and Dissertations

Set against the backdrop of the mid-twentieth century American Midwest, Marilynne Robinson's Lila is a profound story of loss and redemption told through the perspective of a young woman who emerges from a childhood of trauma and neglect and begins a new life in the quiet town of Gilead, Iowa. This paper examines the novel as a narrative meditation on the theological and ontological dimensions of wonder. While its fragmented structure and bleak subject matter have led some critics to interpret the novel as emotionally fractured or pessimistic, I argue that its recursive form and narrative disorientation are deliberate formal …

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Learning Stations As A Dialogical Teaching Strategy In English Language Arts, Kaylee Smedley Apr 2025

Learning Stations As A Dialogical Teaching Strategy In English Language Arts, Kaylee Smedley

Theses and Dissertations

Researchers and teachers advocating for dialogical teaching in secondary English language arts classrooms value dialogical strategies because they offer flexible approaches to comprehension and learning (Wilkinson & Son, 2011). While research on dialogic pedagogy recognizes strategies that privilege student talk, connect reading and writing to students' life experiences, and value multiple perspectives as beneficial, research about learning stations--where students rotate through a series of learning activities in small, collaborative groups (Aydogmus & Senturk, 2019)--and their role in fostering dialogical learning remains limited. This article explores how learning stations supported the application of dialogical principles through an inquiry-based literature unit and …

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The Crystal Ball Is Cloudy: Teacher Preparation Programs' Challenges In Predicting Effective Teaching From Teacher Characteristics, Benjamin Pacini Apr 2025

The Crystal Ball Is Cloudy: Teacher Preparation Programs' Challenges In Predicting Effective Teaching From Teacher Characteristics, Benjamin Pacini

Theses and Dissertations

Teacher preparation programs (TPPs) stand to benefit if they can reliably link pre-service teacher characteristics with later teaching quality--for example, by better supporting underperformers and spotting high-potential candidates early. In this study, I use data from a university in the Mountain West to analyze the relationships between pre-college student characteristics and teaching evaluation scores during student teaching, as scored on Danielson's Framework for Teaching (FFT) rubric. My findings suggest that no significant relationship exists between FFT scores and demographic characteristics such as age, sex, marital status, or poverty. Pre-college academic variables (i.e., GPA and standardized test scores) show small but …

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Pilot Study For Examining The Physiological Effects Of Sustained Attention In A Structured Online Mindfulness-Based Course, Eve Barton Apr 2025

Pilot Study For Examining The Physiological Effects Of Sustained Attention In A Structured Online Mindfulness-Based Course, Eve Barton

Theses and Dissertations

Mindfulness-based interventions (MBI's) and courses have emerged as widely recognized approaches for promoting mental health, improving cognitive functioning, and fostering overall well-being. This pilot study explored the effects of a 15-session, online, structured mindfulness course on sustained attention and subjective well-being, utilizing both objective and subjective measures. The study aimed to determine whether participants' sustained attention, assessed via a smooth pursuit eye movement (SPEM) task, improved after completing the online course. Subjective attention was measured using the Attentional Control Scale (ACS) and a single item from the Adult ADHD Self-Report Scale (ASRS), while subjective well-being was assessed using the Survey …

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Wordsworth's Literary Signposts: Writings On Epitaphs And Tourism, 1807-1835, Matthew W. Rudy Apr 2025

Wordsworth's Literary Signposts: Writings On Epitaphs And Tourism, 1807-1835, Matthew W. Rudy

Theses and Dissertations

This paper explores the intersection of epitaphic language and tourism in the works of William Wordsworth from 1807-1835. Compared to his earlier, more literal epitaphs, works such as "Yarrow Unvisited" (1807) and "Elegiac Stanzas" (1807) demonstrate a shift towards broader epitaphic language that foregrounds the ability of epitaphic texts to invite the reader to pause and make their own connection with the inscribed site. With the publication of "Essay upon Epitaphs" (1810) he further established his theory on the ideal epitaph as text capable of anticipating and connecting anonymous readers to the site and subject, whether inscribed on a headstone …

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Enabling Next-Generation Microfluidics Through Advances In High-Resolution 3d Printing, Matthew S. Viglione Apr 2025

Enabling Next-Generation Microfluidics Through Advances In High-Resolution 3d Printing, Matthew S. Viglione

Theses and Dissertations

This dissertation advances the field of microfluidic device fabrication through the development and application of high-resolution 3D printing technologies. The convergence of stereolithography (SLA) with digital light processing (DLP) has created unprecedented opportunities for microfluidic device fabrication, enabling truly three-dimensional structures with feature sizes approaching the single-micron scale. Building upon foundational work in custom 3D printer development, this research addresses critical limitations in 3D printing that have historically constrained microfluidic innovation, spanning multiple generations of custom 3D printers and technical innovations that have enabled the fabrication of increasingly complex microfluidic devices while enhancing resolution, repeatability, speed, and accessibility. A comprehensive …

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A Complete Guide To Multi-Fidelity No-U-Turn Sampling With Application To An Inverse Wave Problem, Paul Smith Apr 2025

A Complete Guide To Multi-Fidelity No-U-Turn Sampling With Application To An Inverse Wave Problem, Paul Smith

Theses and Dissertations

We employ a Bayesian framework to solve an inverse problem that aims to identify the initial condition distribution of wave propagation, given a limited set of observable data. To optimize sampling efficiency, we introduce a multi-fidelity No-U-Turn Sampler (MF-NUTS) with an adaptive mass matrix. Maximizing sampling efficiency is crucial, as our ultimate goal is to extend this methodology to a large-scale inverse problem to identify the source parameters of historical tsunami-generating earthquakes. The forward model for tsunami propagation (GeoClaw) requires over 20 minutes of supercomputer time on 24 cores to evaluate each sample for a triple-fault rupture, necessitating a strategy …

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Reading "Particularized Worlds": Apocalypse, The Postsecular, And Postcritique In Toni Morrison's A Mercy, Eli Phillips Apr 2025

Reading "Particularized Worlds": Apocalypse, The Postsecular, And Postcritique In Toni Morrison's A Mercy, Eli Phillips

Theses and Dissertations

Toni Morrison’s 2008 novel A Mercy uses the concepts of world and apocalypse to explore a tension between individual perception (what Morrison calls “particularized worlds”) and larger social systems. In so doing, A Mercy reveals the nuanced networks of relationships that define worlds of belief and culture. By exploring its treatment of worlds and apocalypse and its attitudes toward the characters who experience them, this paper argues that Morisson’s work demonstrates a novel and timely readerly disposition, one that provides a more ethical approach to reading literature within the postcritical and postsecular landscape.

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Deliberate Practice For Multicultural Orientation Training Novice Undergraduates, Eduardo E. Duran Apr 2025

Deliberate Practice For Multicultural Orientation Training Novice Undergraduates, Eduardo E. Duran

Theses and Dissertations

This study explores the efficacy of Multicultural Orientation (MCO) and Motivational Interviewing (MI) frameworks in enhancing undergraduates' ability to address cultural dynamics in therapeutic contexts through deliberate practice. Using a randomized control trial design, 59 participants were assigned to either an MCO as the experimental group or an MI workshop as the control group, each involving pre- and post-workshop video simulations and self-reported assessments. The workshops incorporated deliberate practice exercises with feedback to improve participants' responses to culturally rich client scenarios. Findings indicated significant improvements in cultural humility, comfort, and opportunities for the MCO group compared to the MI group. …

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A Low-Cost Micro Actuator Driven By Electrowetting-On-Dielectric, Behzad Parsi Apr 2025

A Low-Cost Micro Actuator Driven By Electrowetting-On-Dielectric, Behzad Parsi

Theses and Dissertations

Microfluidic techniques have been shown to address limitations of reconfigurable radio frequency (RF) antennas and filters in efficiency, power handling capability, cost, and frequency tuning. However, the current devices suffer from significant integration challenges associated with packaging, actuation, and control. Recent advances in reconfigurable microfluidics that utilize the motion of a selectively metalized plate (SMP) for RF tuning have demonstrated promising RF capabilities but have exposed a need for an accurate fluid actuation model. This research presents models for the dynamics of plate actuation under multiple scenarios. In the first phase, the mechanical motion of a moving plate (e.g. SMP) …

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Intervention Strategies To Overcome Hpv Vaccine Hesitancy Among Hispanic Immigrants In The Usa: A Video-Based Ap-Proach, Jamie Jensen Apr 2025

Intervention Strategies To Overcome Hpv Vaccine Hesitancy Among Hispanic Immigrants In The Usa: A Video-Based Ap-Proach, Jamie Jensen

ScholarsArchive Data

These data come from a nationwide survey administered by Qualtrics testing a video intervention to help Hispanic Immigrants overcome barriers to HPV vaccination.

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Studies Evaluating Practices For Water Conservation: In-Situ Sensors For Determining Soil Field Capacity And Water Application Savings From Rebate-Driven Residential Landscape Transformations, Madison E. Martini Apr 2025

Studies Evaluating Practices For Water Conservation: In-Situ Sensors For Determining Soil Field Capacity And Water Application Savings From Rebate-Driven Residential Landscape Transformations, Madison E. Martini

Theses and Dissertations

Water conservation is a critical issue that requires solutions to address growing water scarcity. In both agricultural and urban settings, targeting conservation efforts is essential for lasting progress as well as protection of communities and ecosystems. This research focuses on identifying practical means to reduce water use by studying separate conservation strategies in urban and agricultural contexts. Given their interdependence, addressing water use in both sectors is essential for achieving meaningful and lasting conservation outcomes. Agricultural water conservation relies on efficient irrigation practices, which depend on accurately determining soil field capacity (FC)--the amount of water soil can retain after excess …

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Ledger Lines And Lines Of Flight: Borges, Deleuze, And Music, Kaitlyn Thiriot Morin Apr 2025

Ledger Lines And Lines Of Flight: Borges, Deleuze, And Music, Kaitlyn Thiriot Morin

Theses and Dissertations

This paper discusses the purpose of musical inclusions within several of Jorge Luis Borges’s short stories through Deleuzian lines of flight. The common consideration of music in Borges’s works focuses primarily on his usage of the tango and milonga due to Borges’s own personal interests. This paper argues that Borges utilizes not only the tango but also other styles of music as a pathway of transcendence, temporarily allowing characters to surpass the limitations of mortality. The paper will first analyze Deleuze and Guattari’s formula on escaping organization, and the relationship between the rhizome, lines of flight, deterritorialization, and the body …

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Associations Between Linguistic Factors And Vaccine Attitudes In A Hispanic Immigrant Population In The United States, Jamie Jensen Apr 2025

Associations Between Linguistic Factors And Vaccine Attitudes In A Hispanic Immigrant Population In The United States, Jamie Jensen

ScholarsArchive Data

Data are results of a nationwide survey administered by Qualtrics to Hispanic Immigrants concerning HPV vaccine uptake and hesitancy factors.

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Optimizing Aircraft Taxi Processes: A Novel Cost-Minimizing Queue Discipline For The Pushback To Runway Process, Kevin James Apr 2025

Optimizing Aircraft Taxi Processes: A Novel Cost-Minimizing Queue Discipline For The Pushback To Runway Process, Kevin James

Theses and Dissertations

Optimization of the aircraft taxi process can significantly decrease operating costs for air carriers, especially at major airports where congestion on the ramp is a primary contributor to taxi times. To improve the efficiency of this process, we propose a novel queue discipline which mitigates pushback delays through a dynamic reordering of clearance deliveries. As an alternative to FIFO, the proposed discipline accounts for aircraft delays at the gate before the aircraft enters the queueing system. Our proposed system implements pushback control to allow for controller-imposed variability in runway queueing. To validate our proposed queue discipline, we provide a computational …

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Heavy Ion Testing Of Versal Acap Ai Engines, Caleb S. Price Apr 2025

Heavy Ion Testing Of Versal Acap Ai Engines, Caleb S. Price

Theses and Dissertations

With recent developments in artificial intelligence (AI), there has been an ever increasing need for computation power in space. These AI models are traditionally implemented on GPUs. However, these units come at a high cost in terms of weight and power usage. Due to these limitations, many organizations are turning to the Versal ACAP device, a system on chip (SOC) with hundreds of AI engines. This option delivers more computation per watt than a traditional GPU. The desire to use Versal ACAP in space has created a need to perform radiation testing on the device. Extensive testing has been performed …

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Gnss-Denied Navigation Using Lte Signals Of Opportunity On Low-Cost, Low-Swap Hardware, Tyler Sweat Apr 2025

Gnss-Denied Navigation Using Lte Signals Of Opportunity On Low-Cost, Low-Swap Hardware, Tyler Sweat

Theses and Dissertations

Global navigation satellite system (GNSS) navigation is crucial in the operation of unmanned aerial vehicles (UAV). GNSS signals are susceptible to jamming, spoofing, multipath, and urban canyons and may provide incorrect position information or may not be available at all. For autonomous missions, a backup for GNSS is desirable in the event that it is unavailable. Terrestrial cellular signals are a promising option for navigation because they are continuously transmitted at higher power levels. Optimizing hardware size, weight, and power (SWaP) is critical for UAVs to maximize endurance, payload capacity, and operational efficiency. We present a system that uses long-term …

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Understanding Dialogic Interactions In Online Religious Education, Isaac Munoz Moreno Apr 2025

Understanding Dialogic Interactions In Online Religious Education, Isaac Munoz Moreno

Theses and Dissertations

In this study, I explored how Latter-day Saint higher education professors experienced and facilitated dialogic interactions in online religion courses. Seven instructors who taught synchronous and asynchronous virtual courses at Brigham Young University participated in semi-structured interviews focused on their pedagogical approaches, relational practices, and perceptions of student engagement. Guided by hermeneutic phenomenology and drawing on principles of dialogic pedagogy, I explored how religion instructors cultivated dialogue in virtual classrooms grounded in doctrinal instruction. The findings revealed how professors created a relational presence, navigated institutional constraints, and fostered deep learning and spiritual growth environments. While some participants viewed online dialogue …

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The Role Of Positive Psychology Within Professional Athletes’ Performance, Jasmine C. Olsen Apr 2025

The Role Of Positive Psychology Within Professional Athletes’ Performance, Jasmine C. Olsen

ScholarsArchive Data

This literature review delves into the influence of these practice such as mental resilience, coach-to-athlete relationships, and satisfaction in performance within athletes. It’s aim is to voice any needed changes within such research for future studies.

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Measuring The Effects Of The Leaves On Stalk Strength And Dynamic Response In Maize, Grant C. Ogilvie Apr 2025

Measuring The Effects Of The Leaves On Stalk Strength And Dynamic Response In Maize, Grant C. Ogilvie

Theses and Dissertations

Maize is one of the most widely cultivated grains in the world, making it crucial to world food security and important economically. One major problem in maize production is stalk lodging (greensnap), which results in billions of dollars in lost harvests annually for maize farmers in the US alone. Understanding the mechanical properties of maize plants is crucial to addressing this problem. Previous studies have suggested that the leaf blades and leaf sheaths affect maize mechanical properties. The objectives of this thesis are twofold: to present measurement techniques for the stalk bending strength, damping ratio, and natural frequency of maize …

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A Novel Wrench Decomposition And Development Of A Large-Scale Soft Robot For Displacement-Based Human-Robot Collaborative Manipulation, Dallin Cordon Apr 2025

A Novel Wrench Decomposition And Development Of A Large-Scale Soft Robot For Displacement-Based Human-Robot Collaborative Manipulation, Dallin Cordon

Theses and Dissertations

This work represents an examination of various facets of physical human-robot collaborative manipulation and the implementation of compliant, soft-robotic manipulators. A survey of physical human-human interaction and haptic communication is presented, alongside an investigation into the decomposition of force and torque components that enable effective human-robot collaboration. To address the inconsistent terminology found in previous literature, a standardized framework for force decomposition is proposed. A new taxonomy is introduced to categorize the force components involved in collaborative manipulation tasks. This taxonomy clarifies the role of each component in an agent's applied force during task execution and provides a structured framework …

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Testing And Modeling Of Nonlinearities In Riveted And Bolted Structures, Joshua E. Blackham Apr 2025

Testing And Modeling Of Nonlinearities In Riveted And Bolted Structures, Joshua E. Blackham

Theses and Dissertations

Joints are difficult to model because of various small-scale and nonlinear features, such as local geometry, preload, friction and contact. These features cause a local change in stiffness and energy dissipation which result in changes in the effective natural frequency and damping of the whole structure. Past studies have found good success using nonlinear Iwan elements as whole joint models for bolted joints in a few different structures. In Chapter 3, a similar approach is proposed for modeling riveted joints, which seeks to capture the vibrational response of a test structure including changes in the effective modal frequency and damping …

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