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Innovations In Sample Handling Automation To Increase Accessibility Of Sample-Limited Proteomics, Nathaniel Ben Axtell Apr 2025

Innovations In Sample Handling Automation To Increase Accessibility Of Sample-Limited Proteomics, Nathaniel Ben Axtell

Theses and Dissertations

Innovation is the vehicle that drives scientific research forward in virtually every field. Advances in genome sequencing propelled the human genome project to completion in 2003 and set the stage for the era of proteomics. Now decades of innovation in liquid chromatography (LC) and mass spectrometry (MS) have improved sensitivity sufficiently to enable single-cell proteomics and other sample-limited studies. Single-cell proteomics reveal patterns of gene expression that are often obscured by bulk-scale proteomics, leading to the identification of new protein biomarker candidates. Sensitive targeted proteomics is the key to successful translation of low-abundance protein assays into clinical applications. With a …

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Exploring The Associations Between Young Adults' Autistic Traits And Parental Differential Treatment, Madelyn Winder Bennett Apr 2025

Exploring The Associations Between Young Adults' Autistic Traits And Parental Differential Treatment, Madelyn Winder Bennett

Theses and Dissertations

The current study sought to identify autistic traits that may elicit parental differential treatment (PDT). Understanding these links are important because numerous studies have shown PDT to have negative implications for healthy development. Participants (recruited via Amazon Mechanical Turk) completed a survey assessing their experiences of parental differential treatment and their own autistic traits using the Autism Quotient (AQ) measure (Baron-Cohen et al., 2001). Participants were young adults ages 18-29 (M age = 25.4; 57% Female, 43% Male; 73% White, n = 739) who resided in the U.S. and had at least one living sibling. Using regression analysis, we examined …

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Influence Of The Duchesne Fault Zone On Oil Production In The Uinta Basin, Utah, Alan Matthew Ketring Apr 2025

Influence Of The Duchesne Fault Zone On Oil Production In The Uinta Basin, Utah, Alan Matthew Ketring

Theses and Dissertations

The Duchesne Fault Zone (DFZ) is a series of east-west trending en echelon faults that developed synchronously above the neutral surface of the Duchesne Anticline during the Laramide Orogeny. The Duchesne Graben (DG) formed by decrease in displacement downward toward the neutral surface. Lake Canyon, a region that exposes the subsurface geology on the western portion of the DFZ, serves as an analog for fold formation within the saline facies of the lower Green River Formation, while Indian Canyon, an area created from the dip-slip faulting of the DG, provides clear exposures of the faulting within the sandstone-limestone facies of …

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Mythology Of Autism: Pop Culture, Rhetoric, And Vaccines, Makenzi Strate Apr 2025

Mythology Of Autism: Pop Culture, Rhetoric, And Vaccines, Makenzi Strate

Theses and Dissertations

Myths are stories told to provide an explanation for the unknown, reflect cultural beliefs of populations that hold them, and lack scientific evidence to support these stories. Some myths, such as the myth that vaccines cause autism, are harmful toward the groups that they target. Popularized in 1998 with the publication of the Wakefield study, the myth that vaccines cause autism continues to spread and thrive today. To understand the widespread nature and detriments of belief in harmful myths such as this, I implement mythology rhetoric to examine how celebrity Jenny McCarthy utilizes elements of myth to persuade others to …

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Advancing Global Flood Inundation Mapping From Srtm To Fabdem, Taylor James Miskin Apr 2025

Advancing Global Flood Inundation Mapping From Srtm To Fabdem, Taylor James Miskin

Theses and Dissertations

This study evaluates how elevation and hydrography inputs influence flood extent accuracy using ARC (Automated Rating Curve), a raster-based flood inundation model. It focuses on how spatial resolution and vertical accuracy, reflecting the satellite mission from which each dataset was derived, and bare-earth processing of the DEM affect the accuracy of predicted flood extents. The assessment compares four dataset combinations--FABDEM with GEOGLOWS River Forecasting System Version 1(RFS1), FABDEM with GEOGLOWS River Forecasting System Version 2(RFS2), SRTM with RFS1, and SRTM with RFS2--across five study locations: the Suncook River in New Hampshire, North Fork Kentucky River in Kentucky, Nimishillen Creek in …

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Teaching Information Synthesis In First-Year Writing: A Replication And Extension Study, Rachel M. Terry Apr 2025

Teaching Information Synthesis In First-Year Writing: A Replication And Extension Study, Rachel M. Terry

Theses and Dissertations

This study investigates the challenges and strategies associated with teaching information synthesis to first-year college students. Synthesis, a higher-order cognitive skill described as "knowledge-transforming," is critical for academic success and informed engagement in an information-saturated society. However, many students enter college with underdeveloped foundational reading and writing skills, compounded by declining literacy rates and the prevalence of fragmented digital content consumption. This study builds on prior research in composition, education, and information literacy to address three key questions: (1) How do students understand synthesis? (2) What strategies do students employ when attempting to synthesize information? (3) What instructional implications arise …

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Language Choice And Russian Course Enrollment Among University Students, Emma Calderwood Apr 2025

Language Choice And Russian Course Enrollment Among University Students, Emma Calderwood

Theses and Dissertations

University Russian enrollments have been steadily declining in the United States since 2009 (MLA, 2023). No research has been done to examine student motivation for studying Russian since long before the 2022 increase in conflict between Russia and Ukraine. This study surveys two groups of students at the university level: students enrolled in BYU 101-level language classes, and students enrolled in Russian classes at six universities in the United States. The findings report that the most common reasons students choose to take university Russian classes is because they have a general interest in the language, they want to travel to …

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Studying Cultural Change With Transhistorical Semantic Directions, Travis Daichi Ashby Apr 2025

Studying Cultural Change With Transhistorical Semantic Directions, Travis Daichi Ashby

Theses and Dissertations

This study advances the use of diachronic word embeddings in cultural sociology, contributing both methodologically and substantively. Methodologically, it synthesizes best practices for constructing semantic directions and addresses challenges arising from diachronic embeddings, including missing data and semantic drift. Substantively, it examines historical changes in schemas and conceptual metaphors related to "processing." By analyzing the changing associations between processing-related words (e.g., "raw" and "refined") and evaluative categories like authenticity, valence, and aesthetics, the study examines whether word-level changes amongst schematically-related words indicate deeper cultural shifts at the schematic level. Findings indicate a growing association between processed states and inauthenticity, a …

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Inquiry-Style Planetarium Activities, Emma Rasmussen Groberg Apr 2025

Inquiry-Style Planetarium Activities, Emma Rasmussen Groberg

Theses and Dissertations

Introductory astronomy students often face challenges in exploring their own ideas and investigating astronomical phenomena due to the limitations of nighttime observation and weather conditions. Planetariums overcome these barriers by simulating the night sky, making it accessible during class sessions regardless of external conditions. This provides an opportunity to engage students in inquiry-based activities, where they are presented with a scenario and encouraged to use their own reasoning to reach conclusions. In this study, we implemented inquiry-based activities in PHSCS 127 using the planetarium as an investigative tool. We developed four activities designed to help students explore their ideas and …

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Reconstruction Of Cad Models Into Single Trimmed Surfaces, Rebecca Rasmussen Apr 2025

Reconstruction Of Cad Models Into Single Trimmed Surfaces, Rebecca Rasmussen

Theses and Dissertations

Classical methods by which computer-aided design (CAD) geometries are represented for both design and analysis involve meshing. However, the current process of converting a CAD model into an analysis-suitable surface mesh for the automotive industry takes a significant amount of time and labor, results in a faceted representation of the original smooth geometry, and generates representations that are prohibitively expensive for use in high-order explicit dynamics computations. This research focuses on accurately and efficiently rebuilding given CAD surfaces or meshes, such as shell-like components of automotive vehicles, into smooth, single trimmed spline surface approximations (rather than typical piecewise-linear approximations), making …

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Modeling The Kepler Systems With Multiple Transiting Planets, Daniel Kempton Jones Apr 2025

Modeling The Kepler Systems With Multiple Transiting Planets, Daniel Kempton Jones

Theses and Dissertations

As the study of exoplanets, planets not in our solar system, has developed, new observational constraints have illuminated the formation and evolution of planetary systems. Among these observations, the true distributions of planetary mass, radius, and density are at the forefront. NASA's Kepler Space Telescope has provided an enormous wealth of data on the exoplanet radius distribution as well as a significant fraction of mass measurements through the detection of planet-planet dynamical interactions. The best method for studying these exoplanetary systems is with a photodynamical model which combines an n-body integrator with lightcurve model to generate synthetic lightcurves. To support …

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The Influence Of Leaders And Managers In Commercial Construction, Samuel F. Merrill Apr 2025

The Influence Of Leaders And Managers In Commercial Construction, Samuel F. Merrill

Theses and Dissertations

This research explores how the distinct traits of leadership and management influence supervisory effectiveness and employee experiences in Utah's commercial construction sector. While leadership and management are often conflated, this study draws on foundational literature that defines leadership as people-centered, visionary, and empowering. In contrast, management is characterized as results-driven, process-oriented, and focused on control. Using survey data from 95 individuals working in commercial construction, the study evaluates how supervisors with leadership or managerial characteristics are perceived by their teams. Supervisors were categorized based on observable behaviors selected by respondents, distinguishing leadership traits from managerial traits. Supervisors identified as leaders …

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Reclaiming Identity: Miné Okubo's Self-Portraiture And Authorship In Citizen 13660, Caroline E. Johnson Apr 2025

Reclaiming Identity: Miné Okubo's Self-Portraiture And Authorship In Citizen 13660, Caroline E. Johnson

Theses and Dissertations

In this thesis, I argue that Miné Okubo's repeated self-portraiture in Citizen 13660 asserts her authority of the soul author of the text, forcing her reader to acknowledge the perspective in which the story is being told. Through the images of herself, she makes clear the fact that the story is filtered through her personal experience, rather than the widely accepted understanding that the novel is a universal story. While the written account strives for a sense of objectivity, the images of Okubo, especially when analyzed through the context of her contemporaries, including comics and photographers, shows how her work …

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Organismal Classification And The Phylogenetic Tree: Improving Its Teaching Using Decision-Based Learning, Melissa Cavan Apr 2025

Organismal Classification And The Phylogenetic Tree: Improving Its Teaching Using Decision-Based Learning, Melissa Cavan

Theses and Dissertations

For a lot of students, learning biology is like learning a new language. There are new terms and concepts that a lot of new students have never heard of. Evolution is the cornerstone for understanding biology, yet it is one of the more misunderstood topics. In combination with learning new terms and concepts some students come in with preconceived ideas about evolution or misunderstandings about how evolution and the phylogenetic tree work. The research indicates instructors attempting active learning techniques to increase understanding of the phylogenetic tree with mixed results, where there appears to be some improvement but nothing significant. …

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"The Things I Hate": Romans 7 And The Construction Of Self, Nicole Francis Apr 2025

"The Things I Hate": Romans 7 And The Construction Of Self, Nicole Francis

Theses and Dissertations

The construction of the self has been a central topic of discussion throughout Graeco-Roman history and continues to shape modern theoretical debate. This paper situates Paul’s construction of self in Romans 7 within these ongoing conversations, engaging both ancient and modern perspectives. While many scholars have written books on the topic of the Hellenistic and Roman constructions of self that include thinkers such as Plato, Aristotle, Cicero, Seneca, Epictetus, and others, none of these extant works have explored Paul’s contribution to this discourse. Acknowledging the historical interests and the academic conversations about the historical Paul, this paper seeks to add …

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The Value Of Alternative Credentials To Earners And Employers, Daniel O. Young Apr 2025

The Value Of Alternative Credentials To Earners And Employers, Daniel O. Young

Theses and Dissertations

Between the rising cost of education and the oft-mentioned skills gap, current and potential students are pursuing alternatives to expensive 4-year degrees. This has contributed to the rapid rise of alternative credentials over the past 10 years. However, these alternatives still struggle with public awareness, questions of validity, and familiarity and acceptance by employers. This dissertation focuses on understanding the research surrounding alternative credentials and specifically looks at whether those credentials have perceived or actual value for gaining or improving an individual's career. To better understand this topic, I looked to the literature for context, and used data gathered from …

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Differential Binding Of Host Cell Proteins By Vpr Mutant R77q Compared With Wild Type Vpr, Madison C. Wagley Apr 2025

Differential Binding Of Host Cell Proteins By Vpr Mutant R77q Compared With Wild Type Vpr, Madison C. Wagley

Theses and Dissertations

HIV Viral protein R (Vpr) is a multifunctional accessory protein which plays a role in nuclear import of the pre-integration complex, transactivation of HIV LTR promoter, cell cycle arrest, and apoptosis during HIV infection. R77Q is an HIV Vpr mutant which is associated with long-term non-progressor phenotypes, and which has previously been connected to higher levels of apoptosis compared to wild type Vpr in vitro. There are observable differences in host binding partners with HIV Vpr between wild type and R77Q strains as shown via coimmunoprecipitation and mass spectrometry. In one run R77Q samples showed binding to histone 1.2, 1.3, …

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Development Of Raman Spectroscopic Methods To Analyze Chemical, Biological, And Physical Constituents For Food Safety And Quality, Hannah C. Broadbent Apr 2025

Development Of Raman Spectroscopic Methods To Analyze Chemical, Biological, And Physical Constituents For Food Safety And Quality, Hannah C. Broadbent

Theses and Dissertations

Ensuring food safety and quality is crucial for consumer health, satisfaction, and regulatory compliance. This study aims to develop rapid, reliable methods for detecting food constituents (i.e. lactose), pathogens (i.e. Listeria monocytogenes), and contaminants (i.e. micro- and nano-plastics) using Raman spectroscopy. With advantages like high specificity, minimal sample preparation, and fast analysis, Raman spectroscopy offers a promising alternative to traditional methods. This research explores its application in assessing chemical, biological, and physical properties of food to enhance safety and quality monitoring. Lactose-free products are increasingly popular due to the global prevalence of lactose intolerance, creating a need for effective verification …

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Partial Replication Of The Severe Outcome Questionnaire (S-Oq): Determining Benchmarks Using Ecologically Valid Data, Joshua J. Allen Apr 2025

Partial Replication Of The Severe Outcome Questionnaire (S-Oq): Determining Benchmarks Using Ecologically Valid Data, Joshua J. Allen

Theses and Dissertations

Background: The Severe Outcome Questionnaire (S-OQ) is a self-report tool whose most recent manual was published in 2008. It measures the treatment progress of the seriously mentally ill (SMI). Objective: 1). Partially replicate the outpatient and inpatient admission, change, and internal consistency data. 2). Provide a manual extension including admission and change data for new settings of care and include treatment modality benchmarks. Method: OQ Measures provided an archival data set drawn from six different community mental health organizations from around the United States covering 101 different clinics (N = 25,511; Male = 11,524, Female = 13,987). We constructed normative …

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Gender Differences In Food Parenting, Lily Arrowood Apr 2025

Gender Differences In Food Parenting, Lily Arrowood

Student Works

Children’s food behavior can be determined by food parenting practices, which can differ between mother and father. This review aims to present the most current research on the difference in parenting styles between fathers and mothers and the influences on children’s food behavior. Searches were conducted through EBSCO database and the National Library of Medicine database to produce 10 peer-reviewed articles that were empirical studies. Findings about nutritional risk and nutrition education were inconclusive. A relationship exists between fathers and coercive food parenting strategies. There are inconclusive findings about children’s environment, but mothers contributed to more foodwork and used supportive …

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Hydrologic Decision Support In The Nile Basin: Creating Status And Outlook Products From The Geoglows Hydrologic Model, Rachel Huber Apr 2025

Hydrologic Decision Support In The Nile Basin: Creating Status And Outlook Products From The Geoglows Hydrologic Model, Rachel Huber

Theses and Dissertations

Decision makers and stakeholders need information about current and future streamflow to make informed decisions and we show how the GEOGLOWS Hydrologic Model, known as River Forecast System (RFS), can be used to provide hydrologic status and outlook products to inform these decisions. We examine a specific use case of RFS in the Nile River Basin and how RFS is used to provide users with hydrologic status products. We work with stakeholders at the Nile Basin Initiative to assess their needs for this information. We use basic low flow calculations to compute the Standardized Streamflow Index (SSI) and the 95th …

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Human Passion In The City And The Jungle: Translating Horacio Quiroga’S “Dieta De Amor,” “El Simún,” And “Polea Loca”, Washington C. Pearce Apr 2025

Human Passion In The City And The Jungle: Translating Horacio Quiroga’S “Dieta De Amor,” “El Simún,” And “Polea Loca”, Washington C. Pearce

Theses and Dissertations

Horacio Quiroga, Uruguayan-Argentine writer who is often considered analogous to Edgar Allan Poe, is notable for his contributions to the development of South American Modernismo and his status as a precursor to the Latin American "Boom" period. My project presents a translation of three previously untranslated short stories: "Dieta de Amor," "El Simún," and "Polea Loca." As a preface to these translations I articulate my translation theory and give examples of that theory in practice. I draw upon Jorge Luis Borges, Lawrence Venuti, and Friedrich Schleiermacher as translation scholars who have influenced my work.

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Systematic Analysis On The Applications Of Infrastructure Asset Management In Utah, Kelvin Kozakevitch Apr 2025

Systematic Analysis On The Applications Of Infrastructure Asset Management In Utah, Kelvin Kozakevitch

Theses and Dissertations

Public infrastructure is essential to a region’s economic stability and quality of life, especially its rural infrastructure where most consumable and essential goods derive from. Given the high capital investment required for infrastructure development and maintenance, asset management plans (IAM) are critical. Even though academic research exists on the problems rural infrastructure management face, little is known about the actual state, barriers and causes for the challenges IAM faces in rural Utah. This study examines the current challenges and barriers in IAM among rural communities in Utah. Employing a grounded theory approach, data was collected through a two-phase methodology: phase …

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Wordsworth's Literary Signposts: Writings On Epitaphs And Tourism, 1807-1835, Matthew W. Rudy Apr 2025

Wordsworth's Literary Signposts: Writings On Epitaphs And Tourism, 1807-1835, Matthew W. Rudy

Theses and Dissertations

This paper explores the intersection of epitaphic language and tourism in the works of William Wordsworth from 1807-1835. Compared to his earlier, more literal epitaphs, works such as "Yarrow Unvisited" (1807) and "Elegiac Stanzas" (1807) demonstrate a shift towards broader epitaphic language that foregrounds the ability of epitaphic texts to invite the reader to pause and make their own connection with the inscribed site. With the publication of "Essay upon Epitaphs" (1810) he further established his theory on the ideal epitaph as text capable of anticipating and connecting anonymous readers to the site and subject, whether inscribed on a headstone …

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Enabling Next-Generation Microfluidics Through Advances In High-Resolution 3d Printing, Matthew S. Viglione Apr 2025

Enabling Next-Generation Microfluidics Through Advances In High-Resolution 3d Printing, Matthew S. Viglione

Theses and Dissertations

This dissertation advances the field of microfluidic device fabrication through the development and application of high-resolution 3D printing technologies. The convergence of stereolithography (SLA) with digital light processing (DLP) has created unprecedented opportunities for microfluidic device fabrication, enabling truly three-dimensional structures with feature sizes approaching the single-micron scale. Building upon foundational work in custom 3D printer development, this research addresses critical limitations in 3D printing that have historically constrained microfluidic innovation, spanning multiple generations of custom 3D printers and technical innovations that have enabled the fabrication of increasingly complex microfluidic devices while enhancing resolution, repeatability, speed, and accessibility. A comprehensive …

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Associations Between Linguistic Factors And Vaccine Attitudes In A Hispanic Immigrant Population In The United States, Jamie Jensen Apr 2025

Associations Between Linguistic Factors And Vaccine Attitudes In A Hispanic Immigrant Population In The United States, Jamie Jensen

ScholarsArchive Data

Data are results of a nationwide survey administered by Qualtrics to Hispanic Immigrants concerning HPV vaccine uptake and hesitancy factors.

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Optimizing Aircraft Taxi Processes: A Novel Cost-Minimizing Queue Discipline For The Pushback To Runway Process, Kevin James Apr 2025

Optimizing Aircraft Taxi Processes: A Novel Cost-Minimizing Queue Discipline For The Pushback To Runway Process, Kevin James

Theses and Dissertations

Optimization of the aircraft taxi process can significantly decrease operating costs for air carriers, especially at major airports where congestion on the ramp is a primary contributor to taxi times. To improve the efficiency of this process, we propose a novel queue discipline which mitigates pushback delays through a dynamic reordering of clearance deliveries. As an alternative to FIFO, the proposed discipline accounts for aircraft delays at the gate before the aircraft enters the queueing system. Our proposed system implements pushback control to allow for controller-imposed variability in runway queueing. To validate our proposed queue discipline, we provide a computational …

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Heavy Ion Testing Of Versal Acap Ai Engines, Caleb S. Price Apr 2025

Heavy Ion Testing Of Versal Acap Ai Engines, Caleb S. Price

Theses and Dissertations

With recent developments in artificial intelligence (AI), there has been an ever increasing need for computation power in space. These AI models are traditionally implemented on GPUs. However, these units come at a high cost in terms of weight and power usage. Due to these limitations, many organizations are turning to the Versal ACAP device, a system on chip (SOC) with hundreds of AI engines. This option delivers more computation per watt than a traditional GPU. The desire to use Versal ACAP in space has created a need to perform radiation testing on the device. Extensive testing has been performed …

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Understanding Dialogic Interactions In Online Religious Education, Isaac Munoz Moreno Apr 2025

Understanding Dialogic Interactions In Online Religious Education, Isaac Munoz Moreno

Theses and Dissertations

In this study, I explored how Latter-day Saint higher education professors experienced and facilitated dialogic interactions in online religion courses. Seven instructors who taught synchronous and asynchronous virtual courses at Brigham Young University participated in semi-structured interviews focused on their pedagogical approaches, relational practices, and perceptions of student engagement. Guided by hermeneutic phenomenology and drawing on principles of dialogic pedagogy, I explored how religion instructors cultivated dialogue in virtual classrooms grounded in doctrinal instruction. The findings revealed how professors created a relational presence, navigated institutional constraints, and fostered deep learning and spiritual growth environments. While some participants viewed online dialogue …

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Testing And Modeling Of Nonlinearities In Riveted And Bolted Structures, Joshua E. Blackham Apr 2025

Testing And Modeling Of Nonlinearities In Riveted And Bolted Structures, Joshua E. Blackham

Theses and Dissertations

Joints are difficult to model because of various small-scale and nonlinear features, such as local geometry, preload, friction and contact. These features cause a local change in stiffness and energy dissipation which result in changes in the effective natural frequency and damping of the whole structure. Past studies have found good success using nonlinear Iwan elements as whole joint models for bolted joints in a few different structures. In Chapter 3, a similar approach is proposed for modeling riveted joints, which seeks to capture the vibrational response of a test structure including changes in the effective modal frequency and damping …

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